Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3573 produits trouvés pour "Nucléosides"
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5'-O-DMT-2'-O-methyl-5-iodouridine 3'-CE-phosphoramidite
5'-O-DMT-2'-O-methyl-5-iodouridine 3'-CE-phosphoramidite is a novel nucleoside, which has been synthesized by the activation of 5'-O-DMT-2'-O-methyluridine 3'-CE with phosphorous tribromide. It has been tested for antiviral and anticancer activities, as well as its ability to inhibit HIV replication in vitro. This compound is also useful for the synthesis of other nucleosides.Degré de pureté :Min. 95%5-(2-Fluorovinyl)-2'-Deoxyuridine
CAS :5-(2-Fluorovinyl)-2'-Deoxyuridine is a hydrophobic analogue of acyclovir that has potent activity against herpes simplex virus type 1. It inhibits the synthesis of viral DNA, and thus prevents the formation of plaques in tissue culture. This drug also inhibits cell proliferation and viral production by l1210 cells as well as lung fibroblasts. 5-(2-Fluorovinyl)-2'-Deoxyuridine has shown inhibitory effects against uninfected cells, but not against cells infected with herpes simplex virus type 2.Formule :C11H13FN2O5Degré de pureté :Min. 95%Masse moléculaire :272.23 g/mol2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine
CAS :2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a purine nucleoside where the purine base has a 2-amino group at position 2 and a chlorine at position 6. The sugar is 2'-deoxy, meaning it is like the sugar found in DNA, lacking the 2'-hydroxyl group that is present in RNA. The amino and chloro groups on the purine base modify how this molecule behaves in biological systems making it useful in research applications.Formule :C10H12ClN5O3Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :285.69 g/mol2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine
CAS :2'-Deoxy-2'-fluoro-N2-isobutyrylguanosine is a modified nucleoside analog for research applicationsFormule :C14H18FN5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :355.33 g/molFialuridine - Bio-X ™
CAS :This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C9H10FIN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :372.09 g/mol2'-Deoxy-6-thioguanosine - Bio-X ™
CAS :This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Formule :C10H13N5O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.31 g/mol9-(b-D-Arabinofuranosyl)-8-chloroadenine
CAS :9-(b-D-arabinofuranosyl)-8-chloroadenine is a deoxyribonucleoside that is structurally related to adenosine. It has antiviral properties and has been shown to be active against herpes virus, influenza A virus, and cytomegalovirus. 9-(b-D-Arabinofuranosyl)-8-chloroadenine is an activator of cellular DNA polymerase δ and has been shown to inhibit the replication of HIV in human T lymphocytes. 9-(b-D-Arabinofuranosyl)-8-chloroadenine also inhibits the proliferation of tumor cells and is being investigated as a potential chemotherapeutic agent for cancer treatment.
Degré de pureté :Min. 95%N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-tritylcytidine 3-CE phosphoramidite
N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-tritylcytidine 3-CE phosphoramidite is an antiviral, anticancer, and activator molecule that is a monophosphate. It has been shown to be active against DNA viruses such as herpes simplex virus type 1, hepatitis B virus, and human immunodeficiency virus type 1. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-tritylcytidine 3-CE phosphoramidite can also be used in the synthesis of deoxyribonucleosides or ribonucleosides. This molecule has novel and modified structures that make it useful in the synthesis of nucleoside analogues with improved pharmacokinetics.Formule :C50H62N5O7PSiDegré de pureté :Min. 95%Masse moléculaire :904.14 g/molN1-Methylpseudouridine-5'-triphosphate trisodium
Please enquire for more information about N1-Methylpseudouridine-5'-triphosphate trisodium including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C10H14N2Na3O15P3Masse moléculaire :564.11 g/mol2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine
2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine is an antiviral nucleoside that is chemically synthesized from 5-methoxyuridine. It has been shown to inhibit the replication of HIV in cell cultures and animal models. This drug can be used as a phosphoramidite for the synthesis of oligonucleotides. 2’,3’-Bis-O-tert-butyldimethylsilyl-5-methoxyuridine is a novel nucleoside that has not been previously reported in the chemical literature.Degré de pureté :Min. 95%N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine
CAS :Produit contrôléN4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine is a nucleoside that is modified by the attachment of an acetyl group at the 2' position. It is used as a component in the synthesis of oligonucleotides and can also be used in antiviral and anticancer applications. N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine is synthesized by reacting 4,5′-dihydroxybenzoic acid with 4-(dimethylamino)pyridine and diisopropylethylamine to form an intermediate, which reacts with cytosine to produce the desired product. This process requires high purity, which can be achieved through high quality production methods.Formule :C22H31N3O6SiDegré de pureté :Min. 95%Masse moléculaire :461.58 g/mol5-O-Benzoyl-1,2-O-isopropylidene-3-O-methyl-a-D-xylofuranose
5-O-Benzoyl-1,2-O-isopropylidene-3-O-methyl-a-D-xylofuranose is a modified nucleoside that belongs to the category of deoxyribonucleosides. It is an antiviral agent that has been shown to be active against Herpes simplex virus type 1. 5-O-Benzoyl-1,2,3,4,5,6 -hexahydrobenzo[e]pyrazine (BENZOPYR) is a potent activator of DNA synthesis and phosphorylation in mammalian cells. The modification of this nucleoside allows for its use as a monophosphate in the synthesis of DNA or RNA. 5ODAP is also used as a substrate for phosphoramidite chemistry in the preparation of oligodeoxynucleotides for use in DNA sequencing and other biotechnological applications.Degré de pureté :Min. 95%5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine
5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside that can be used as an antiviral and anticancer agent. It has shown to be more potent than other nucleosides in inhibiting the synthesis of viral DNA and RNA, which makes it a potential candidate for treating HIV infection and cancer. This drug can also act as an activator by stimulating the production of deoxyribonucleotides and ribonucleotides. 5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine has been shown to have high purity and quality, making it a good candidate for use in various fields of research.
Formule :C11H13F2N3O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :305.23 g/molN6-Benzoyl-2'-deoxy-2'-fluoroadenosine
CAS :N6-Benzoyl-2'-deoxy-2'-fluoroadenosine is an oligonucleotide that can be used to modulate the expression of survivin. It inhibits the expression of this protein by binding to its mRNA and preventing translation. N6-Benzoyl-2'-deoxy-2'-fluoroadenosine has shown potential for use in cancer treatment due to its ability to inhibit tumor growth and metastasis. It may also be used in the treatment of autoimmune diseases, such as rheumatoid arthritis, where it can inhibit the production of inflammatory cytokines.
Formule :C17H16FN5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :373.34 g/mol5'-O-DMT-thymidine 3'-CE phosphoramidite
CAS :5'-O-DMT-thymidine 3'-CE phosphoramidite is a building block for the introduction of thymidine units into oligonucleotides. 5'-O-DMT-thymidine 3'-CE phosphoramidite is utilised in a broad range of applications, including the synthesis of natural and unnatural DNA and RNA strands. Phosphoramidites are the reagent class of choice for oligonucleotide synthesis as they contain readily removable orthogonal protecting groups and can be produced at reasonable scales. The diisopropylamino leaving group is readily cleaved upon exposure to an azole catalyst allowing for a highly efficient coupling reaction with a free hydroxyl group on the growing oligonucleotide and oxidation of the subsequent phosphite triester, followed by beta-elimination of the cyanoethyl group affords the stable phosphodiester linkage.Formule :C40H49N4O8PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :744.83 g/molN4-Acetyl-2'-deoxy-5'-O-tritylcytidine
CAS :N4-Acetyl-2'-deoxy-5'-O-tritylcytidine is a novel nucleoside that is synthesized by modifying cytidine to form an acetylated nucleotide. It has been found to be an effective inhibitor of DNA synthesis and antiviral agent.Formule :C30H29N3O5Degré de pureté :Min. 95%Masse moléculaire :511.57 g/mol5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It is an activator that can be used in the synthesis of oligonucleotide analogues, such as ribonucleosides and deoxyribonucleosides. 5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite has shown anticancer activity.Formule :C30H40N7O7PDegré de pureté :Min. 95%Masse moléculaire :641.67 g/molPalmitoyl coenzyme A potassium salt
CAS :Palmitoyl coenzyme A potassium salt is a novel, modified nucleoside that has antiviral and anticancer activities. It is a phosphoramidite with a phosphate group at one end and a palmitoyl group at the other. The phosphate group is attached to the 5' position of the sugar, while the palmitoyl group is attached to the 3' position of the sugar. Palmitoyl coenzyme A potassium salt can be used in DNA synthesis.Formule :C37H65N7O17P3SKDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :1,044.03 g/mol2'-Chloro-2'-deoxycytidine
CAS :2'-Chloro-2'-deoxycytidine is a synthetic nucleoside analog. It is a modified deoxycytidine with a chlorine atom at the 2'-position of the deoxyribose sugar. This molecule can be used in research applicationsFormule :C9H12ClN3O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :261.66 g/molN4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite
CAS :Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides. Using a chemical approach rather than an enzymatic one allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Differently from the enzymatic synthesis, the chemically synthesised oligonucleotide sequence is typically constructed in a 3’ to 5’ direction. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite, also called 5-Me-DMT-2'-O-MOE-C(Bz)-CEP, has been used in the synthesis of oligonucleotides which are specifically hybridizable with nucleic acids encoding multidrug resistant-associated protein (MRP). The antisense oligonucleotide ISIS 13041 gave almost complete removal of resistance to vincristine, a chemotherapy drug.Formule :C50H60N5O10PDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :922.01 g/mol
