Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.539 produits)
- Apoptose(5.812 produits)
- Cycle cellulaire/point de contrôle(4.460 produits)
- Chromatine/Épigénétique(2.245 produits)
- Signalisation du cytosquelette(1.381 produits)
- Altération de l'ADN/réparation de l'ADN(2.829 produits)
- Endocrinologie/Hormones(3.517 produits)
- Enzyme(3.640 produits)
- GPCR/G-Protéine(8.357 produits)
- Immunologie et Inflammation(3.538 produits)
- Virus de la grippe(296 produits)
- Signalisation JAK/STAT(405 produits)
- Signalisation MAPK(1.203 produits)
- Transporteur membranaire/Canal ionique(2.806 produits)
- Métabolisme(9.456 produits)
- Microbiologie/Virologie(6.998 produits)
- Neuroscience(9.938 produits)
- Autres inhibiteurs(37.853 produits)
- Oxydation-Réduction(40 produits)
- Signalisation PI3K/Akt/mTOR(1.399 produits)
- Protéases/Protéasome(1.600 produits)
- Cellules souche et Dérivés(831 produits)
- Tyrosine Kinase/Adaptateurs(2.016 produits)
- Ubiquitination(1.650 produits)
Affichez 16 plus de sous-catégories
66626 produits trouvés pour "Inhibiteurs"
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Myxothiazol
CAS :<p>Myxothiazol blocks mitochondrial complex III and triggers SESN2, a gene important for stress response.</p>Formule :C25H33N3O3S2Couleur et forme :SolidMasse moléculaire :487.68KDOAM-25 citrate
CAS :<p>KDOAM-25 citrate inhibits KDM5A/B/C/D (IC50: 71, 19, 69, 69 nM); boosts H3K4 methylation, hinders MM1S cell growth. [1]</p>Formule :C21H33N5O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :499.51AK-295
CAS :<p>AK 295, also known as CX 295, is a dipeptide inhibitor of alpha-ketoamide calpain.</p>Formule :C26H40N4O6Couleur et forme :SolidMasse moléculaire :504.62Antioxidant agent-8
<p>Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation & promotes disaggregation; it's neuroprotective & BBB permeable.</p>Formule :C13H12O5Couleur et forme :SolidMasse moléculaire :248.235-HT6/5-HT2AR antagonist-1
<p>Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.</p>Formule :C21H26N6SCouleur et forme :SolidMasse moléculaire :394.54PF-07054894
CAS :<p>PF-07054894: potent CCR6 antagonist, targets GPCR, for inflammatory bowel disease research.</p>Formule :C24H30N6O4Couleur et forme :SolidMasse moléculaire :466.53ZLMT-12
<p>ZLMT-12: tacrine derivative, inhibits CDK2/CDK9, weak on AChE/BuChE, anti-proliferative, low toxicity, blocks S/G2/M phase, induces apoptosis.</p>Formule :C26H31ClN6OCouleur et forme :SolidMasse moléculaire :479.02EB-0150
<p>EB-0150 inhibits ER α-Glu I/II (IC50: 0.73/0.0337 μM), is an N-substituted valerian with antiviral effects, and has drug discovery potential.</p>Formule :C19H30N6O7Couleur et forme :SolidMasse moléculaire :454.48AChE-IN-5
<p>AChE-IN-5: oral, crosses blood-brain barrier, targets AChE/5-HT1A/SERT, potent with 2.29 nM IC50.</p>Formule :C38H45N5OCouleur et forme :SolidMasse moléculaire :587.8ODN 2088
CAS :<p>ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.</p>Couleur et forme :SolidKDOAM-25 trihydrochloride (2230731-99-2 free base)
<p>KDOAM-25 trihydrochloride, a selective KDM5 inhibitor (IC50: 19-71 nM), boosts H3K4 methylation and hinders MM1S cell growth.</p>Formule :C15H28Cl3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.77Nipradolol
CAS :<p>Nipradolol blocks alpha-1-adrenergic receptors, lowers IOP in rabbits, and reduces NA-induced muscle contraction and dog artery vasodilation.</p>Formule :C15H22N2O6Couleur et forme :SolidMasse moléculaire :326.35Carumonam Sodium
CAS :<p>Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials.</p>Formule :C12H12N6Na2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.37Exicorilant
CAS :<p>Exicorilant is a selective oral GR antagonist (Ki: 7 nM) that may reduce obesity, glucose intolerance, & dyslipidemia.</p>Formule :C26H23F4N7O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :589.56SGK1-IN-3
<p>SGK1-IN-3: Potent oral inhibitor of SGK1, may target osteoarthritis.</p>Formule :C23H20Cl2N6O3SCouleur et forme :SolidMasse moléculaire :531.41SB-612111
CAS :<p>SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.</p>Formule :C24H29Cl2NOCouleur et forme :SolidMasse moléculaire :418.40KH-259
<p>KH-259: potent, selective CNS-penetrant HDAC6 inhibitor with 0.26 μM IC50; shows antidepressant effects in mice.</p>Formule :C20H25N3O2Couleur et forme :SolidMasse moléculaire :339.43Latrunculins A
CAS :Latrunculins A is a novel marine toxin, disrupts microfilament organization in cultured cells.Formule :C22H31NO6SCouleur et forme :SolidMasse moléculaire :437.55BGC-638
CAS :<p>BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)–overexpressing tumors.</p>Formule :C32H33N5O9Couleur et forme :SolidMasse moléculaire :631.63Adiaft
CAS :<p>Adiaftis a bioactive chemical.</p>Formule :C10H11IN2O4Couleur et forme :SolidMasse moléculaire :350.11PARP7-IN-12
CAS :<p>PARP7-IN-12, a potent inhibitor targeting PARP7, exhibits an IC50 of 7.836 nM. This compound is applicable in cancer research.</p>Formule :C23H27ClF3N5O5Couleur et forme :SolidMasse moléculaire :545.94Dopamine D3 receptor antagonist-1
<p>Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic</p>Formule :C31H35Cl2N3O3Couleur et forme :SolidMasse moléculaire :568.53F 14679
CAS :<p>F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.</p>Formule :C21H25ClF2N4ODegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :422.9Elacestrant S enantiomer
<p>Elacestrant S enantiomer is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively.</p>Formule :C30H38N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.63DNA gyrase B-IN-1
<p>DNA gyrase B-IN-1, a potent inhibitor of P. aeruginosa DNA gyrase B, has IC50 of 2.2 μM with high affinity and stability.</p>Formule :C23H18ClF3N6O4SCouleur et forme :SolidMasse moléculaire :566.94DC41SMe
CAS :<p>DC41SMe, a DC1 derivative and CC-1065 analogue, targets cancer with 18-25 pM IC50 against Ramos, Namalwa, HL60/s cells.</p>Formule :C38H36ClN5O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :726.31Laulimalide
CAS :<p>Microtubule stabilizer; halts cancer cell growth (IC50: 3-30 nM); arrests cells in prometaphase; prevents bipolar spindle formation.</p>Formule :C30H42O7Couleur et forme :SolidMasse moléculaire :514.65BTK-IN-10
CAS :<p>BTK-IN-10 is a potent inhibitor of BTK, acting on wild-type BTK (IC50<5 nM) or mutant BTK (C481S) (IC50<5 nM).</p>Formule :C25H24F2N4O2Couleur et forme :SolidMasse moléculaire :450.48TS010
<p>TS010 is a highly potent inhibitor of GLO-I, with an IC50 value of 0.57 μM. It holds significant promise for advancements in cancer research [1].</p>Formule :C16H12N4O4SCouleur et forme :SolidMasse moléculaire :356.36Antimalarial agent 9
<p>Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.</p>Formule :C28H32BrN3O2Couleur et forme :SolidMasse moléculaire :522.48PI3Kα-IN-8
<p>PI3Kα-IN-8 is a selective inhibitor of PI3Kα (IC50: 0.012 μM).</p>Formule :C26H27BrN4O2Couleur et forme :SolidMasse moléculaire :507.42NTU281
CAS :<p>NTU281 inhibits transglutaminase-2, lowers creatinine in diabetic rats, reduces proteinuria, and fights glomerulosclerosis.</p>Formule :C25H31N2O6SCouleur et forme :SolidMasse moléculaire :487.59CYP2C1/CYP2C19-IN-2
<p>CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.</p>Formule :C27H28N2O6SCouleur et forme :SolidMasse moléculaire :508.59IDO1-IN-13
<p>IDO1-IN-13 is a potent IDO1 inhibitor (IC50: 61.6 nM, EC50: 30 nM in HeLa) that reduces kyn/trp ratio by 51% in SK-OV-3 tumors.</p>Formule :C20H16BrN5O2SCouleur et forme :SolidMasse moléculaire :470.34NF-κB-IN-4
<p>NF-κB-IN-4 (compound 17) is a potent inhibitor of NF-κB pathway which can cross blood brain barrier (BBB).</p>Formule :C18H15FN4OCouleur et forme :SolidMasse moléculaire :322.34rel-MDM2/4-p53-IN-2
<p>Potent dual MDM2/MDM4 inhibitor & p53 activator; IC50: 70.7 nM (MDM2), 81.4 nM (MDM4); regulates cell cycle, triggers apoptosis, anti-cancer.</p>Formule :C25H17Cl3FN3O3Couleur et forme :SolidMasse moléculaire :532.78BMS-681
CAS :<p>BMS-681 is a CCR2 antagonist blocking chemokine binding, aiding control of inflammatory and neurodegenerative diseases.</p>Formule :C26H36F3N5OCouleur et forme :SolidMasse moléculaire :491.59Pelecopan
CAS :<p>Pelecopan (BCX9930), an oral complement factor D inhibitor, prevents hemolysis in PNH (IC50=14.3 nM).</p>Formule :C23H19FN2O4Couleur et forme :SolidMasse moléculaire :406.41RAD51-IN-5
CAS :<p>RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)</p>Formule :C26H38N4O5S2Couleur et forme :SolidMasse moléculaire :550.73Cilobamine mesylate
CAS :<p>Cilobamine mesylate is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects.</p>Formule :C18H27Cl2NO4SCouleur et forme :SolidMasse moléculaire :424.38SARS-CoV-2-IN-24
<p>SARS-CoV-2-IN-24 blocks PLpro, altering its shape and stopping virus replication—useful for SARS-CoV-2 research.</p>Formule :C27H30N4O5Couleur et forme :SolidMasse moléculaire :490.55C-di-IMP
CAS :<p>Cyclic-di-IMP (C-di-IMP), a STING agonist, serves as a research tool in tumor studies.</p>Formule :C20H22N8O14P2Couleur et forme :SolidMasse moléculaire :660.38TLR7/8 antagonist 1
<p>Compound 16c, an imidazoquinoline, is a TLR7/8 agonist; IC50: 3.91 μM (TLR7), 2.19 μM (TLR8); targets TLR-2050 for disease treatment.</p>Formule :C24H27N5O2Couleur et forme :SolidMasse moléculaire :417.5Mevidalen HBA
CAS :<p>Mevidalen (LY3154207), a potent D1 positive allosteric modulator, is in clinical trials for Lewy body dementia.</p>Formule :C31H35Cl2NO6Couleur et forme :SolidMasse moléculaire :588.52Eprociclovir Na
CAS :<p>Eprociclovir Na (A-5021) is 15x stronger than acyclovir at inhibiting herpesviruses, showing promise for EHV1 and herpetic keratitis treatment.</p>Formule :C11H14N5NaO3Couleur et forme :SolidMasse moléculaire :287.25AM-3189
CAS :<p>AM-3189: potent, selective GPR40 agonist with low CNS penetration, good pharmacokinetics, and efficacy mirroring AMG 837.</p>Formule :C27H25ClN2O3Couleur et forme :SolidMasse moléculaire :460.95LTD4 antagonist 1
CAS :<p>LTD4 antagonist 1 is a potent and orally active antagonist of leukotriene D4 (LTD4; Ki: 0.57 nM).</p>Formule :C31H32F3N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :615.66SPR719
CAS :<p>SPR719 is an inhibitor of gyrase B, has bactericidal activity.</p>Formule :C21H25FN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.46BACE1-IN-4
CAS :<p>BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.</p>Formule :C21H23F2N5O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.57Carbonic anhydrase inhibitor 5
<p>Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.</p>Formule :C24H20ClN3O3SCouleur et forme :SolidMasse moléculaire :465.95Kallikrein-IN-1
CAS :<p>Kallikrein-IN-1 (Formula A) is an inhibitor of the kinin-releasing enzyme Kallikrein.</p>Formule :C28H26FN5O4Couleur et forme :SolidMasse moléculaire :515.54PF-00446687
CAS :PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).Formule :C28H36F2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.59Tubulin polymerization-IN-4
CAS :<p>Tubulin polymerization-IN-4: inhibits tubulin (IC50=4.6 μM), blocks G2/M phase, induces apoptosis, hinders cell cloning/migration, damages vasculature.</p>Formule :C21H21ClN2O4Couleur et forme :SolidMasse moléculaire :400.86Antiviral agent 15
<p>Compound 15f, a Clofazimine derivative, inhibits rabies (EC50: 1.45 μM) and SARS-CoV-2 (EC50: 14.6 μM).</p>Formule :C27H24FN5OCouleur et forme :SolidMasse moléculaire :453.51CDK1-IN-4
<p>CDK1-IN-4 inhibits CDK1 (IC50: 44.52 nM), CDK2/CDK5 less potently, impacts cell cycle, used in cancer studies.</p>Formule :C26H24ClN5SCouleur et forme :SolidMasse moléculaire :474.02cSPM
<p>cSPM (Cyclic spermine) is an Aβ42 inhibitor. cSPM inhibits the aggregation of three different peptides, Aβ42, tryptophan and insulin, and reduces cytotoxicity.</p>Formule :C27H57N7Couleur et forme :SolidMasse moléculaire :479.79NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Formule :C14H9IN2O3SCouleur et forme :SolidMasse moléculaire :412.2Antiangiogenic agent 2
<p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>Formule :C26H26FN3O4Couleur et forme :SolidMasse moléculaire :463.5ORP-101
CAS :<p>ORP-101: large, stable molecule with partial μ agonist, full κ antagonist properties.</p>Formule :C60H84N2O8Couleur et forme :SolidMasse moléculaire :961.32Bcl-2-IN-6
<p>Bcl-2-IN-6 suppresses Bcl-2, upregulates p53/Bax/caspase-7, arrests cell cycle, and induces MCF-7 apoptosis; IC50s: MCF-7 20.91 μM, others <48 μM.</p>Formule :C25H24N4O5S2Couleur et forme :SolidMasse moléculaire :524.6116(R)-Iloprost
CAS :<p>Iloprost, a potent prostacyclin analog, binds IP & EP1 receptors (Ki 11 nM), contains 16(S/R) isomers, and inhibits platelets (IC50 65 nM).</p>Formule :C22H32O4Couleur et forme :SolidMasse moléculaire :360.49PARP10/15-IN-2
CAS :<p>PARP10/15-IN-2 (Compound 8h) blocks PARP10/15, has IC50s: 0.15μM/0.37μM, cell-permeable, prevents apoptosis.</p>Formule :C15H11FN2O3Couleur et forme :SolidMasse moléculaire :286.26Antibacterial agent 118
<p>Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.</p>Formule :C19H21N5O2SCouleur et forme :SolidMasse moléculaire :383.47APJ receptor agonist 3
CAS :<p>APJ receptor agonist 3 is a highly effective and orally administerable agonist of the APJ receptor, demonstrating a potent EC50 value of 0.027 nM.</p>Formule :C26H29ClN4O5Couleur et forme :SolidMasse moléculaire :512.98Ro 24-4383
CAS :<p>Ro 24-4383 is a carbamate-linked dual-action antibacterial agent.</p>Formule :C32H31FN8O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :770.76(Rac)-Plevitrexed
CAS :<p>(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).</p>Formule :C26H25FN8O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.53LSD1-IN-22
<p>LSD1-IN-22: potent LSD1 inhibitor, K_i 98 nM, curbs cancer cell growth.</p>Formule :C9H8BrF2NCouleur et forme :SolidMasse moléculaire :248.07Dyrk1A-IN-2
<p>Dyrk1A-IN-2 is a DYRK1A inhibitor (EC50: 37 nM). dyrk1A-IN-2 exhibits efficient promotion of human β-cell replication, as well as low cytotoxicity.</p>Formule :C27H32N6O4Couleur et forme :SolidMasse moléculaire :504.58NMDA receptor antagonist-3
<p>NMDA antagonist-3: recovery rate 40% at 100 μM, low toxicity in SH-SY5Y, human stem cells.</p>Formule :C13H19N3O6Couleur et forme :SolidMasse moléculaire :313.31MA242 free base
CAS :<p>MA242 free base is a dual MDM2/NFAT1 inhibitor that triggers apoptosis in pancreatic cancer cells.</p>Formule :C24H20ClN3O3SCouleur et forme :SolidMasse moléculaire :465.95ATM Inhibitor-4
<p>ATM Inhibitor -4: selective, potent (IC50: 0.32 nM), inhibits PI3K family, stable, stops mTOR at 1 μM.</p>Formule :C26H29FN6O3Couleur et forme :SolidMasse moléculaire :492.55Sucistil
<p>Sucistil is an active biochemical. hemoglobin sucistil (bovine) is an oxygen carrier [1].</p>Formule :C9H15NO4SCouleur et forme :SolidMasse moléculaire :233.28Glyphosate-trimesium
CAS :<p>Glyphosate-trimesium is a herbicide.</p>Formule :C6H16NO5PSCouleur et forme :SolidMasse moléculaire :245.23Oncopterin
CAS :<p>Oncopterin is found in urine from patients with solid and blood cancers.</p>Formule :C12H18N6O3Couleur et forme :SolidMasse moléculaire :294.31Antibacterial synergist 1
<p>Compound 20P is a potent antibacterial, inhibits biofilms with IC50 4.5 μM, and reduces pyocyanin at IC50 8.6 μM.</p>Formule :C19H24N2O4Couleur et forme :SolidMasse moléculaire :344.4BRL-42715
CAS :<p>BRL-42715 is an effective inhibitor of bacterial beta-lactamases.</p>Formule :C10H7N4NaO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :286.24Cryptopleurine
CAS :<p>Cryptopleurine is an inhibitor of gene products associated with cell proliferation, survival, invasion and angiogenesis. It acts by targeting the NF-κB pathway.</p>Formule :C24H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48Homopteroic Acid
CAS :<p>Homopteroic Acid, a precursor to Homofolic Acid, inhibits L1210 mouse leukemia growth by targeting folate uptake.</p>Formule :C15H14N6O3Couleur et forme :SolidMasse moléculaire :326.31L 668411
CAS :L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.Formule :C19H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.44CCR1 antagonist 11 hydrochloride
<p>Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.</p>Couleur et forme :SolidSB 204070 hydrochloride
CAS :<p>SB 204070 hydrochloride is an inhibitor of beta-lactamase, it is isolated from Spondias mombin.</p>Formule :C19H27ClN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.88DAD
<p>DAD is an ion channel blocker (blocks voltage-gated potassium channels) and is a third generation photoelectric switch that responds to visible light.</p>Formule :C26H40N6OCouleur et forme :SolidMasse moléculaire :452.64KR-67607
CAS :<p>KR-67607, or NTX-101, is a novel 11β-HSD1 inhibitor that protects against eye injury by reducing cortisol and preserving eye structures.</p>Formule :C24H29Cl2F3N4O4SCouleur et forme :SolidMasse moléculaire :597.48ZK159222
CAS :<p>ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.</p>Formule :C32H48O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.72VEGFR-2-IN-15
<p>VEGFR-2-IN-15 (Compound 14b) is a potent inhibitor of VEGFR-2. VEGFR-2-IN-15 inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.</p>Formule :C23H18ClN3O4SCouleur et forme :SolidMasse moléculaire :467.92ADP-2341
<p>ADP-2341 is a soluble analog of FiVe1.</p>Formule :C24H29Cl2N5O3Couleur et forme :SolidMasse moléculaire :506.43AL 6598
CAS :<p>AL 6598, a prodrug of PGD2 agonist AL 6556, reduces IOP by 53% at 1μg twice daily in monkeys; binds DP receptors with Ki of 3.2μM.</p>Formule :C23H39ClO5Couleur et forme :SolidMasse moléculaire :431.01AD013
<p>AD013 is a selective ACE inhibitor and NEP inhibitor with potential anti-hypertensive and cardioprotective benefits.</p>Formule :C24H28N2O5Couleur et forme :SolidMasse moléculaire :424.49MB725
CAS :<p>MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.</p>Formule :C18H21IN4O2SCouleur et forme :SolidMasse moléculaire :484.35(R)-ZG197
<p>(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.</p>Formule :C28H35F3N4O3Couleur et forme :SolidMasse moléculaire :532.6J-113397
CAS :J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).Formule :C24H37N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.57DS69910557
<p>DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.</p>Formule :C32H33Cl2FN4O3Couleur et forme :SolidMasse moléculaire :611.53AKR1C3-IN-8
<p>AKR1C3-IN-8 (Compound 5) is an effective and selective AKR1C3 inhibitor (IC50=0.069 μM). AKR1C3-IN-8 has antitumor activity.</p>Formule :C23H20N4O3Couleur et forme :SolidMasse moléculaire :400.43Antifungal agent 16
<p>Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.</p>Formule :C27H21N5O2SCouleur et forme :SolidMasse moléculaire :479.55CAII-IN-2
<p>CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.</p>Formule :C18H19BrN4SCouleur et forme :SolidMasse moléculaire :403.34KCa2 channel modulator 2
Compound 2q is a potent, subtype-selective K/Ca 2 modulator, effective on human K Ca 2.3 and rat K Ca 2.2a with EC50s of 0.60 μM and 0.64 μM.Formule :C16H15ClFN5Couleur et forme :SolidMasse moléculaire :331.78SS-RJW100
<p>SS-RJW100 is an enantiomer of RJW100 targeting LRH-1, SF-1, enhances Tif2 interaction, and disrupts LRH-1 networks with lowered stability.</p>Formule :C28H34OCouleur et forme :SolidMasse moléculaire :386.57PDHK-IN-3
<p>PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].</p>Formule :C17H16N2O2Couleur et forme :SolidMasse moléculaire :280.32HIV-1 inhibitor-13
<p>HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).</p>Formule :C30H32N6O3Couleur et forme :SolidMasse moléculaire :524.61Antibiotic MA 144M2
CAS :<p>Antibiotic MA 144M2, an anthracycline glycoside, targets gram-positive bacteria and tumors, derived from Streptomyces and aclacinomycin A conversion.</p>Formule :C42H55NO16Couleur et forme :SolidMasse moléculaire :829.88
