Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.849 produits)
- Apoptose(6.366 produits)
- Cycle cellulaire/point de contrôle(4.907 produits)
- Chromatine/Épigénétique(2.624 produits)
- Signalisation du cytosquelette(1.585 produits)
- Altération de l'ADN/réparation de l'ADN(2.872 produits)
- Endocrinologie/Hormones(3.759 produits)
- Enzyme(3.673 produits)
- GPCR/G-Protéine(9.051 produits)
- Immunologie et Inflammation(3.945 produits)
- Virus de la grippe(300 produits)
- Signalisation JAK/STAT(417 produits)
- Signalisation MAPK(1.259 produits)
- Transporteur membranaire/Canal ionique(3.162 produits)
- Métabolisme(10.149 produits)
- Microbiologie/Virologie(7.672 produits)
- Neuroscience(10.549 produits)
- Autres inhibiteurs(35.858 produits)
- Oxydation-Réduction(41 produits)
- Signalisation PI3K/Akt/mTOR(1.435 produits)
- Protéases/Protéasome(1.693 produits)
- Cellules souche et Dérivés(734 produits)
- Tyrosine Kinase/Adaptateurs(1.991 produits)
- Ubiquitination(1.743 produits)
Affichez 16 plus de sous-catégories
66517 produits trouvés pour "Inhibiteurs"
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RET-IN-7
CAS :RET-IN-7 exhibits strong inhibitory effects against RET kinase in vitro and shows significant efficacy in treating RET-driven tumor xenografts in mice throughFormule :C22H24ClFN6O2Couleur et forme :SolidMasse moléculaire :458.92Elacestrant S enantiomer dihydrochloride
Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.Formule :C30H40Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.56LSD1-IN-19
LSD1-IN-19 is a potent, selective LSD1 inhibitor with Ki of 0.108 μM and 72h IC50 values of 0.17-0.40 μM.Formule :C33H42N6O2Couleur et forme :SolidMasse moléculaire :554.73nNOS-IN-25
CAS :nNOS-IN-25 is an effective, selective, and cell-permeable inhibitor of neuronal nitric oxide synthase.Formule :C21H22N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :330.43Pim-1 kinase inhibitor 3
CAS :Pim-1 kinase inhibitor 3 (Compound H5) is a potent inhibitor of Pim-1 kinase, demonstrating an inhibitory concentration (IC50) of 35.13 nM [1].Formule :C20H25N3O2Couleur et forme :SolidMasse moléculaire :339.43MtTMPK-IN-3
CAS :MtTMPK-IN-3 inhibits Mycobacterium tuberculosis kinase with IC50 0.12μM, MIC 12.5μM on Mtb, cytotoxic EC50 12.5μM on MRC-5 cells.Formule :C23H23Cl2N3O3Couleur et forme :SolidMasse moléculaire :460.35Plumbemycin B
CAS :Plumbemycin B is isolated from Streptomyces plumbeus; an L-threonine antagonist.Formule :C12H21N4O8PCouleur et forme :SolidMasse moléculaire :380.29LpxA-IN-1
CAS :LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosaFormule :C21H11D7F3N5O3Couleur et forme :SolidMasse moléculaire :452.44MDK6465
CAS :MDK6465 (PCSK9-IN-8b), CAS#1900686-46-5, is a liver-targeted PCSK9 synthesis inhibitor.Formule :C27H29ClFN9O4Couleur et forme :SolidMasse moléculaire :598.03DIDS
CAS :DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.Formule :C16H10N2O6S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.52BAY-850 HCl
BAY-850 is a selective probe targeting Atad2A's bromine domain, displacing acetylated H4 peptides and detaching ATAD2 from chromatin at 1μm.Formule :C38H48Cl5N5O3Couleur et forme :SolidMasse moléculaire :800.08Steroid sulfatase-IN-4
Steroid sulfatase-IN-4 irreversibly inhibits human STS with a 25 nM IC50, useful for endometriosis research.Formule :C19H17ClN2O5SCouleur et forme :SolidMasse moléculaire :420.87Lometrexol disodium
CAS :Lometrexol disodium: Inhibits hSHMT1/2 and GARFT, anticancer by blocking purine synthesis, induces apoptosis and cell cycle arrest.Formule :C21H23N5Na2O6Couleur et forme :SolidMasse moléculaire :487.424Urease-IN-1
Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).Formule :C17H12BrFN4O2SCouleur et forme :SolidMasse moléculaire :435.27HDAC6-IN-9
CAS :HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.Formule :C19H16N2O3Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :320.34ONL-1204
CAS :ONL-1204 is a small molecule, CD95 antigen inhibitor (Fas inhibitor) being developed by ONL Therapeutics for the treatment of retinal detachment.Formule :C71H100N18O16Couleur et forme :SolidMasse moléculaire :1461.66PF-00446687
CAS :PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).Formule :C28H36F2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.59Aplaviroc hydrochloride
CAS :Aplaviroc, a potent CCR5 inhibitor, binds selectively, blocking HIV entry and specific monoclonal antibody attachment in vitro.Formule :C33H44ClN3O6Couleur et forme :SolidMasse moléculaire :614.17AMXI-5001 hydrochloride
AMXI-5001 hydrochloride, an oral inhibitor of PARP1/2 and microtubules, shows greater potency and selective anti-cancer effects.Formule :C25H21ClFN5O3Couleur et forme :SolidMasse moléculaire :493.92AKR1C3-IN-5
AKR1C3-IN-5 inhibits AKR1C3, key in prostate/breast cancers, with MCF-7 cell IC50 of 9.6 μM.Formule :C34H44N2O7Couleur et forme :SolidMasse moléculaire :592.72Tzc 5665
CAS :Tzc 5665 is a pyridazinone derivative with vasodilatory and beta-adrenergic blocking activities and type III phosphodiesterase inhibitory action.Formule :C31H38ClN5O7Couleur et forme :SolidMasse moléculaire :628.12TRPV1 antagonist 3
TRPV1 antagonist 3 (7q) strongly blocks TRPV1 at 2.66 nM IC50, is selective, 60% bioavailable, and crosses the blood-brain barrier.Formule :C23H25N3OSCouleur et forme :SolidMasse moléculaire :391.53JAK3/BTK-IN-3
CAS :JAK3/BTK-IN-3: strong dual JAK3/BTK suppressor, promising for autoimmune disease research.Formule :C22H28N8OCouleur et forme :SolidMasse moléculaire :420.51EP-7041 HCl
CAS :EP-7041 is a novel, potent, and selective Factor XIa inhibitor.Formule :C19H27ClN4O4Couleur et forme :SolidMasse moléculaire :410.89LSD1-IN-17
LSD1-IN-17, a potent LSD1/CoREST/MAO inhibitor, IC50: 0.005/0.028/0.820 μM; hinders LNCaP prostate cancer cell growth, IC50: 17.2 μM.Formule :C20H18N2OSCouleur et forme :SolidMasse moléculaire :334.43ATR-IN-17
CAS :ATR-IN-17 is a potent inhibitor of ATR kinase with good anti-cancer effects in LoVo cells (IC50: 1 nM).Formule :C22H28N6O2SCouleur et forme :SolidMasse moléculaire :440.56MRS2179 tetrasodium hydrate
MRS2179 blocks turkey P2Y1 receptor (Kb 102 nM, pA2 6.99), affects platelet aggregation, and has varying IC50s on P2 receptors.Formule :C11H15N5Na4O10P2Couleur et forme :SolidMasse moléculaire :576.21SDM25N hydrochloride
CAS :δ receptor antagonistFormule :C26H27ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :450.96SARS-CoV-2 nsp14-IN-1
SARS-CoV-2 nsp14-IN-1 inhibits Nsp14 Mtase with an IC50 of 0.061 μM, affecting multiple substrates.Formule :C20H20N6O5SCouleur et forme :SolidMasse moléculaire :456.48PARP-1-IN-1
PARP-1-IN-1: Selective, oral PARP-1 inhibitor with 0.96 nM IC50; well-tolerated and effective in single-dose MDA-MB-436 model.Formule :C23H25FN4OCouleur et forme :SolidMasse moléculaire :392.47Refametinib R enantiomer
CAS :Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used
Formule :C19H20F3IN2O5SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :572.34CE-2072
CAS :CE-2072 is a synthetic host serine proteases inhibitor.Formule :C33H41N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.71Dyrk1A/α-synuclein-IN-2
Dyrk1A/α-synuclein-IN-2 (Compound b20) is a dual inhibitor of Dyrk1A and α-synuclein aggregation that acts on α-synuclein (IC50: 7.8 μM).Formule :C21H16N4O4SCouleur et forme :SolidMasse moléculaire :420.44Squalamine lactate
CAS :Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.Formule :C37H71N3O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :718.04Calpain Inhibitor-2
CAS :Calpain Inhibitor-2: Lipophilic, moderates growth of A-375, B-16F1, PC-3 cancers, and hinders 80% DU-145 cell invasion.Formule :C26H33N3O5SCouleur et forme :SolidMasse moléculaire :499.62NITD-688
CAS :NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.Formule :C25H32N4O3S2Couleur et forme :SolidMasse moléculaire :500.68KRAS inhibitor-13
CAS :KRAS inhibitor-13 blocks KRAS G12C (IC50: 0.883 μM) and p-ERK in some cancer cells; promising for pancreatic, colorectal, lung cancer research.Formule :C25H19ClFN3O2SCouleur et forme :SolidMasse moléculaire :479.95FP0429
CAS :FP0429 is an agonist of mGlu4.Formule :C10H12N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :272.21AKR1C3-IN-7
AKR1C3-IN-7 (Compound 13) is an effective and selective AKR1C3 inhibitor (IC50=0.19 μM). AKR1C3-IN-7 has antitumor activity.Formule :C24H20N2O4Couleur et forme :SolidMasse moléculaire :400.43Antibacterial agent 87
Antibacterial agent 87 is an effective antibacterial agent that acts on MRSA (MIC: 0.125 μg/ml), MRSE (MIC: 0.0625 μg/ml) and S. aureus (MIC: 0.0625 μg/ml).Formule :C31H46N2O6SCouleur et forme :SolidMasse moléculaire :574.77Omaciclovir
CAS :Omaciclovir (ABT-091) is a herpesvirus herpesvirus replication inhibitor with antiviral activity that is used in the study of herpesvirus infections.Formule :C10H15N5O3Degré de pureté :99.46% - 99.46%Couleur et forme :SolidMasse moléculaire :253.26L 702007
CAS :L 702007 is an inhibitor of HIV-1 reverse transcriptase.Formule :C18H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.41Leukotriene F-4 sulfone
CAS :Leukotriene F-4 sulfone induces vascular permeability changes.Formule :C28H44N2O10SCouleur et forme :SolidMasse moléculaire :600.72K-14585
CAS :K-14585 blocks PAR(2), reduces NFkappaB activity, and IL-8 response, but alone can boost IL-8.Formule :C51H56Cl2N8O4Couleur et forme :SolidMasse moléculaire :915.95PPARγ agonist 2
PPARγ agonist 2 is a highly effective compound that acts as a partial agonist for PPARγ.Formule :C24H20O5Couleur et forme :SolidMasse moléculaire :388.41MK-8970
MK-8970 is an acetal carbonate prodrug of raltegravir with enhanced colonic absorption.Formule :C25H29FN6O8Couleur et forme :SolidMasse moléculaire :560.54Minnelide
CAS :Minnelide is a prodrug of triptolide,and shows potent antitumor activity in a number of tumor types.Formule :C21H25Na2O10PDegré de pureté :98.49% - 99.59%Couleur et forme :SolidMasse moléculaire :514.37RX 809055AX
CAS :RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.Formule :C29H29ClN2O4Couleur et forme :SolidMasse moléculaire :505Revexepride
CAS :Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.Formule :C21H32ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :425.95PI3K-IN-35
CAS :PI3K-IN-35 (6l) selectively inhibits PI3K-α, β, δ (IC50: 13.98, 7.22, 10.94 μM), blocks G2/M phase, induces apoptosis, and is useful in leukemia research.Formule :C25H23N7O2Couleur et forme :SolidMasse moléculaire :453.5ORP-101
CAS :ORP-101: large, stable molecule with partial μ agonist, full κ antagonist properties.Formule :C60H84N2O8Couleur et forme :SolidMasse moléculaire :961.32SZ1676
CAS :SZ1676 is a derivative of SZ1677, which is an agent of neuromuscular blocking.Formule :C37H59BrN2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :707.78Carboxylesterase-IN-3
CAS :Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.
Formule :C11H6Cl2N4OSDegré de pureté :97.49% - 98.47%Couleur et forme :SolidMasse moléculaire :313.16Antibacterial agent 75
Antibacterial agent 75 re-sensitizes VRSA to vancomycin.Formule :C22H28N6OCouleur et forme :SolidMasse moléculaire :392.5α-Glucosidase-IN-15
α-Glucosidase-IN-15 (Compound 14B) exhibits potent inhibitory activity against α-glucosidase, with an IC50 value of 3.34 μM.Formule :C24H24N2SCouleur et forme :SolidMasse moléculaire :372.53SphK2-IN-2
SphK2-IN-2 (21g) is a potent and selective inhibitor of SphK2 (IC50: 0.23 μM).Formule :C21H25ClN10OCouleur et forme :SolidMasse moléculaire :468.94AS2575959
CAS :AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion.Formule :C32H35NaO7Couleur et forme :SolidMasse moléculaire :554.6148Dexnebivolol
CAS :Dexnebivolol (R67138), a ß-adrenergic antagonist, is Nebivolol's enantiomer with β1 blocking and vasodilation properties.Formule :C22H25F2NO4Couleur et forme :SolidMasse moléculaire :405.43HIV-IN-3
HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.Formule :C21H32ClN7O3Couleur et forme :SolidMasse moléculaire :465.98Antiproliferative agent-8
Compound 5a, an anticancer agent, enhances P53 and has antiproliferative effects.Formule :C22H16ClN3O3Couleur et forme :SolidMasse moléculaire :405.83DAD
DAD is an ion channel blocker (blocks voltage-gated potassium channels) and is a third generation photoelectric switch that responds to visible light.Formule :C26H40N6OCouleur et forme :SolidMasse moléculaire :452.644α-PDD
CAS :4alpha-PDD activates transient receptor potential vanilloid 4 (TRPV4) channels and is inactive for signaling through PKC.Formule :C40H64O8Couleur et forme :SolidMasse moléculaire :672.93CCR5 antagonist 1
CAS :CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.Formule :C39H46ClF2N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :738.33SARS-CoV-2-IN-6
SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with the IC 50 value of 73 nM.Formule :C17H13ClN2O2Couleur et forme :SolidMasse moléculaire :312.75RGB-286638
CAS :RGB-286638 inhibits multiple CDKs and GSK-3β, TAK1, Jak2, MEK1 with IC50s as low as 1-54 nM.Formule :C29H37Cl2N7O4Couleur et forme :SolidMasse moléculaire :618.55SSTR4 agonist 4
CAS :SSTR4 agonist 4, potent in pain research, shows promise in rodent pain models, with potential for Alzheimer's due to hippocampus activity.Formule :C19H26N4OCouleur et forme :SolidMasse moléculaire :326.44BMT-052
CAS :BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).Formule :C30H17D9F4N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :635.61Haspin-IN-1
Haspin-IN-1 blocks haspin (IC50: 119 nM) and inhibits CLK1, DYRK1A, CDK9 with potential as an anticancer drug.Formule :C12H8N4O2SCouleur et forme :SolidMasse moléculaire :272.28Fabimycin
CAS :Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.Formule :C23H25ClN4O3Couleur et forme :SolidMasse moléculaire :440.92Tofacitinib Prodrug-1
Tofacitinib Prodrug-1: an oral prodrug reducing Tofacitinib's side effects, treats ulcerative colitis in mice effectively with low toxicity.Formule :C36H39ClN10O7Couleur et forme :SolidMasse moléculaire :759.21DH376
CAS :DH376 inhibits DAGLα in a time and dose dependent manner in mouse brain. DH376 shows picomolar activity.Formule :C31H28F2N4O3Couleur et forme :SolidMasse moléculaire :542.58BAY-091
CAS :BAY-091 is a novel potent and highly selective PIP4K2A kinase inhibitor.Formule :C26H21FN4O2Degré de pureté :97.66% - 99.23%Couleur et forme :SoildMasse moléculaire :440.47Ref: TM-T60147
500mgÀ demander1mg78,00€5mg168,00€1mL*10mM (DMSO)178,00€10mg269,00€25mg427,00€50mg610,00€100mg820,00€ACT-281959
CAS :ACT-281959, a prodrug of ACT-246475, is a potent P2Y12 antagonist, better than Clopidogrel, effective orally, and in human trials.Formule :C38H55N6O14PCouleur et forme :SolidMasse moléculaire :850.85MAO-B-IN-10
MAO-B-IN-10: Potent, selective MAO-B inhibitor; crosses blood-brain barrier; IC50 5.3 μM; reduces Aβ aggregation 58.2%, disaggregates 43.3%.Formule :C23H26N2O4Couleur et forme :SolidMasse moléculaire :394.46GPR81 agonist 2
CAS :GPR81 agonist 2 is a potent agonist targeting the GPR81 receptor, demonstrating EC50 values of 0.023 µM for hGPR81 and 0.123 µM for hGPR109A, respectively.Formule :C26H27ClN6O5S2Couleur et forme :SolidMasse moléculaire :603.11MEIS-IN-3
MEIS-IN-3 is a potent inhibitor of MEIS.Formule :C25H26N2O4Couleur et forme :SolidMasse moléculaire :418.48BXL0124
CAS :BXL0124 is a gemini vitamin D analog which targets CD44-STAT3 signaling and inhibits breast cancer invasion.Formule :C32H44F6O4Couleur et forme :SolidMasse moléculaire :606.68KOS-1584
CAS :KOS-1584, a safer, more effective epothilone, inhibits cell division by stabilizing microtubules and evading P-gp.Formule :C27H39NO5SCouleur et forme :SolidMasse moléculaire :489.67Top/HDAC-IN-2
Top/HDAC-IN-2 (45b) is a dual inhibitor of Top and HDAC that induces apoptosis and exhibits significant anti-tumour effects.Formule :C30H32N8O4Couleur et forme :SolidMasse moléculaire :568.63DS88790512
CAS :DS88790512, IC50 at 11 nM, is an effective, selective, oral bioeffective TRPC6 inhibitor.Formule :C22H29N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.4820S Proteasome-IN-4
CAS :20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.Formule :C20H18ClF2N3O3Couleur et forme :SolidMasse moléculaire :421.83Chitinase-IN-5
Chitinase-IN-5 (8i) blocks OfChi-h (IC50: 0.051 μM), has insecticidal qualities, useful for eco-friendly pest control.Formule :C20H21ClFN7Couleur et forme :SolidMasse moléculaire :413.88Bizelesin
CAS :Bizelesin, a synthetic antineoplastic agent, binds DNA, disrupts replication, triggers cell-cycle arrest, and induces senescence.Formule :C43H36Cl2N8O5Couleur et forme :SolidMasse moléculaire :815.7Dinordrin
CAS :Dinordrin is an implantation inhibitor and hormone.Formule :C27H36O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.57LSD1-IN-16
LSD1-IN-16 (4b) inhibits LSD1, MAO-A/B; IC50: 0.015-0.366 μM. Halts prostate cancer cell growth; IC50: 15.2 μM.Formule :C20H18N2OSCouleur et forme :SolidMasse moléculaire :334.43AQX-435
CAS :AQX-435 activates SHIP1, inhibits PI3K in BCR signaling, induces apoptosis in B cells, and slows lymphoma growth.Formule :C27H34N2O4Couleur et forme :SolidMasse moléculaire :450.57PI3K-IN-27
CAS :PI3K-IN-27 is a potent PI3K inhibitor, relevant for cancer and immune disease research. See patent WO2021233227A1.Formule :C30H26F2N6O2SCouleur et forme :SolidMasse moléculaire :572.63TP-030-1
CAS :TP-030-1, RIPK1 inhibitor: K(i) hRIPK1 at 3.9nM, IC50 mRIPK1 at 4.2μM; targets inflammation, neurodegeneration research.Formule :C23H22N4O3Couleur et forme :SolidMasse moléculaire :402.45ATR-IN-14
CAS :ATR-IN-14: potent ATR kinase inhibitor; 98.03% inhibition at 25 nM; IC50 of 64 nM in LoVo cells.Formule :C20H20FN7OCouleur et forme :SolidMasse moléculaire :393.42Dup-714
CAS :Dup-714 is a thrombin inhibitor.Formule :C21H33BN6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.33YEATS4 binder-1
YEATS4 binder-1(4e) is an effective and selective compound that targets the KAc recognition site within the YEATS structural domain, exhibiting a bindingFormule :C23H34N4O3Couleur et forme :SolidMasse moléculaire :414.54BRD4-BD1/2-IN-2
CAS :BRD4-BD1/2-IN-2 inhibits BRD4 BD1/BD2 with IC50 <300 nM/<0.5 nM (WO2021233371A1).Formule :C30H33N5O4Couleur et forme :SolidMasse moléculaire :527.61(±)-J 113397
CAS :(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).Formule :C24H37N3O2Couleur et forme :SolidMasse moléculaire :399.57PD-1/PD-L1-IN-16
PD-1/PD-L1-IN-16 is a potent inhibitor of PD-1/PD-L1 (IC50: 53.2 nM) and has shown research potential for tumour immunotherapy.Formule :C34H30N4O4Couleur et forme :SolidMasse moléculaire :558.63LSD1/ER-IN-1
LSD1/ER-IN-1 inhibits ER & LSD1 (IC50: 1.55 μM), and fights MCF-7 breast cancer (IC50: 8.79 μM).Formule :C23H18FNO6SCouleur et forme :SolidMasse moléculaire :455.46BMS-986118
CAS :BMS-986118 is a GPR40 full agonist targeting type II diabetes, prompting insulin release without hypoglycemia risk.Formule :C25H28ClF3N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.96Avibactam sodium dihydrate
Avibactam sodium dihydrate (NXL-104) is a reversible covalent inhibitor for CTX-M-15 and TEM-1 β-lactamases with IC50s of 5 nM and 8 nM.Formule :C7H14N3NaO8SCouleur et forme :SolidMasse moléculaire :323.26Cicaprost
CAS :Cicaprost (ZK 96480) is an IP agonist with artery relaxing effects; EC50 is 5.8 nM.Formule :C22H30O5Couleur et forme :SolidMasse moléculaire :374.47L-2'-Fd4C
CAS :L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].Formule :C9H10FN3O3Couleur et forme :SolidMasse moléculaire :227.19BET-IN-8
BET-IN-8 (Compound 27) is a potent inhibitor of BET (Ki: 0.83 μM, Kd: 0.571 μM), which ameliorates LPS-induced sepsis in vivo.BET-IN-8 has shown potential inFormule :C22H21N3O4SCouleur et forme :SolidMasse moléculaire :423.48
