Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.523 produits)
- Apoptose(5.792 produits)
- Cycle cellulaire/point de contrôle(4.449 produits)
- Chromatine/Épigénétique(2.238 produits)
- Signalisation du cytosquelette(1.383 produits)
- Altération de l'ADN/réparation de l'ADN(2.825 produits)
- Endocrinologie/Hormones(3.507 produits)
- Enzyme(3.640 produits)
- GPCR/G-Protéine(8.333 produits)
- Immunologie et Inflammation(3.526 produits)
- Virus de la grippe(296 produits)
- Signalisation JAK/STAT(404 produits)
- Signalisation MAPK(1.202 produits)
- Transporteur membranaire/Canal ionique(2.790 produits)
- Métabolisme(9.448 produits)
- Microbiologie/Virologie(6.981 produits)
- Neuroscience(9.926 produits)
- Autres inhibiteurs(37.926 produits)
- Oxydation-Réduction(41 produits)
- Signalisation PI3K/Akt/mTOR(1.400 produits)
- Protéases/Protéasome(1.597 produits)
- Cellules souche et Dérivés(831 produits)
- Tyrosine Kinase/Adaptateurs(2.016 produits)
- Ubiquitination(1.650 produits)
Affichez 16 plus de sous-catégories
66641 produits trouvés pour "Inhibiteurs"
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JAK3-IN-7
CAS :<p>JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction after</p>Formule :C17H20N6ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :324.38TP-030-2
CAS :<p>TP-030-2 is a RIPK1 inhibitor (human K i =0.43 nM ; mouse IC 50 =100 nM) .</p>Formule :C23H21BrN4O3Couleur et forme :SolidMasse moléculaire :481.345-Iminodaunorubicin hydrochloride
CAS :<p>5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.</p>Formule :C27H31ClN2O9Couleur et forme :SolidMasse moléculaire :563.00AG-7404
CAS :<p>AG-7404: strong protease inhibitor, fights poliovirus, EC50 0.080-0.674 μM, effective on V-073-resistant strains.</p>Formule :C26H29N5O7Couleur et forme :SolidMasse moléculaire :523.54RhlR antagonist 1
<p>RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.</p>Formule :C12H10F2OCouleur et forme :SolidMasse moléculaire :208.2Methysergide maleate
CAS :<p>Methysergide prevents migraines/cluster headaches; treats serotonin syndrome, carcinoid-induced diarrhea; risk of fibrosis limits use.</p>Formule :C25H31N3O6Degré de pureté :98%Couleur et forme :White To Off-WhiteMasse moléculaire :469.54SCO-792
<p>SCO-792: potent, reversible oral enteropeptidase inhibitor, with slow in vitro dissociation and in vivo protein digestion blocking.</p>Formule :C22H22N4O8·xH2OCouleur et forme :SolidSoyacerebroside II
CAS :<p>Soyacerebroside II is a Ca2+ ionophore; both I and II inhibit IL-18 in PBMCs and modulate immune responses.</p>Formule :C40H75NO9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :714.02HG-12-6
CAS :<p>HG-12-6 is a type II IRAK4 inhibitor, targeting its inactive form with an IC50 of 165 nM, and is used in autoimmunity and inflammation.</p>Formule :C29H27F3N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :580.62HP590
CAS :<p>HP590: potent oral STAT3 inhibitor, IC50=27.8 nM, blocks ATP, IC50=24.7 nM, hinders gastric cancer growth, triggers cell death.</p>Formule :C29H24F6N4O3Couleur et forme :SolidMasse moléculaire :590.52(S)-3-Hydroxy Midostaurin
CAS :<p>(S)-3-Hydroxy Midostaurin is a potent inhibitor of kinases(IC50 of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et)).</p>Formule :C35H30N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.64ChE/Aβ1-42-IN-1
<p>ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability.</p>Formule :C19H24N2O3Couleur et forme :SolidMasse moléculaire :328.41XY153
<p>XY153 (8l) is a BD2 selective BET inhibitor targeting BRD4, 3 & 2 with IC50s: 0.79, 5.31 & 5.09 nM, useful in acute myeloid leukemia & cancer research.</p>Formule :C33H34FN3O4Couleur et forme :SolidMasse moléculaire :555.64HMG499
CAS :<p>HMG499 inhibits HMG-CoA reductase (IC50: 0.41μM), reduces statin-induced HMGCR, lowers cholesterol, and lessens atherosclerosis.</p>Formule :C33H54O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.78Aspochalasin M
CAS :<p>Aspochalasin M shows moderate activity on HL-60 cells (IC50=20.0 μ M). Aspochalasin M has research potential in leukemia diseases.</p>Formule :C24H35NO4Couleur et forme :SolidMasse moléculaire :401.5420S Proteasome-IN-4
CAS :<p>20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.</p>Formule :C20H18ClF2N3O3Couleur et forme :SolidMasse moléculaire :421.83Fonsartan free acid
CAS :<p>Fonsartan: Angiotensin receptor blocker, halts angiotensin II effects on rat vascular cells.</p>Formule :C26H32N4O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :544.69SHP2-IN-9
<p>SHP2-IN-9: Potent SHP2 inhibitor, IC50=1.174 μM, 85x SHP1 selectivity, crosses blood-brain barrier, hampers cancer growth.</p>Formule :C20H20FN3O2SCouleur et forme :SolidMasse moléculaire :385.46CBP/p300-IN-18
<p>CBP/p300-IN-18 (compound 8) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.056 μM) and LK2 H3K27 (IC50: 0.46 μM).</p>Formule :C25H27FN4O3Couleur et forme :SolidMasse moléculaire :450.51GR 83895
CAS :<p>GR 83895 is an antagonist of prototype fibrinogen receptor.</p>Formule :C29H39N9O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :673.74BI 703704
CAS :<p>BI 703704, a soluble guanylate cyclase (sGC) activator, inhibits the progression of diabetic nephropathy in the ZSF1 rat [1].</p>Formule :C32H37N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :559.72KRAS G12D inhibitor 1
CAS :<p>KRAS G12D inhibitor 1 (example 243) is an inhibitor of KRAS G12D with an IC 50 of 0.8 nM for KRAS G12D-mediated ERK phosphorylation [1].</p>Formule :C33H32F2N6O2Couleur et forme :SolidMasse moléculaire :582.64NVP-CGM097 sulfate
CAS :<p>NVP-CGM097 sulfate is a potent and selective inhibitor of MDM2 (hMDM2, IC50 of 1.7±0.1 nM).</p>Formule :C38H49ClN4O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :757.34AVE-1330A free acid
CAS :<p>AVE-1330A free acid is a broad-spectrum non-beta-lactam beta-lactamase inhibitor.</p>Formule :C7H11N3O6SCouleur et forme :SolidMasse moléculaire :265.24Saprisartan potassium
CAS :<p>Saprisartan potassium is an Angiotensin II Type 1 receptor antagonist and antihypertensive agent.</p>Formule :C25H21BrF3KN4O4SCouleur et forme :SolidMasse moléculaire :649.52Nikkomycin Z
CAS :<p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>Formule :C20H25N5O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.44Rubropunctatin
CAS :<p>Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.</p>Formule :C21H23NO4Couleur et forme :SolidMasse moléculaire :353.41HSV-TK substrate
CAS :<p>HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells.</p>Formule :C11H15N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :281.27CHF-6366
CAS :<p>CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.</p>Formule :C42H48N6O8Couleur et forme :SolidMasse moléculaire :764.876-trans-12-epi-Leukotriene B4
CAS :<p>6-trans-12-epi-Leukotriene B4, a metabolite of arachidonic acid, serves as a potent anti-inflammatory agent.</p>Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47Antifungal agent 25
<p>Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.</p>Couleur et forme :SolidTRPC4/5-IN-1
<p>TRPC4/5-IN-1, a TRPC5/4 inhibitor with IC50s 0.54 μM/2.06 μM, targets skin inflammation and proteinuric kidney diseases.</p>Formule :C21H21N3OCouleur et forme :SolidMasse moléculaire :331.41LPM4870108
<p>LPM4870108: Potent, oral pan-Trk inhibitor, selective over ALK, with anti-tumor effects. TrkC IC50=0.2nM, TrkA IC50=2.4nM.</p>Formule :C20H19FN6O3Couleur et forme :SolidMasse moléculaire :410.4Cacospongionolide B
CAS :<p>Cacospongionolide B from Fasciospongia cavernosa inhibits secretory phospholipase A2, curbing inflammation.</p>Formule :C25H36O4Couleur et forme :SolidMasse moléculaire :400.55CTX-712
CAS :<p>CTX-712 is a potent inhibitor of cdc2-like kinase ( CLK ). CTX-712 inhibits inhibits cancer survival and cancer cell growth.</p>Formule :C19H17FN8O2Couleur et forme :SolidMasse moléculaire :408.39KRAS G12C inhibitor 56
CAS :<p>KRAS G12C inhibitor 56, a powerful inhibitor of SOS1 with an inhibitory concentration (IC50) of 1.6 nM, holds promise for use in cancer research.</p>Formule :C32H39N7O4SCouleur et forme :SolidMasse moléculaire :617.76AMD-7049
CAS :<p>AMD-7049 is a biochemical.</p>Formule :C25H39N5Couleur et forme :SolidMasse moléculaire :409.61LRRK2-IN-3
CAS :<p>LRRK2-IN-3: potent, selective oral LRRK2 blocker, BBB-penetrant, IC50 of 0.6 nM in hPBMCs, for Parkinson's research.</p>Formule :C25H29ClF2N6O2Couleur et forme :SolidMasse moléculaire :518.99Bometolol Hydrochloride
CAS :<p>Bometolol Hydrochloride is a beta-adrenergic blocking compound used for the treatment of cardiovascular disease.</p>Formule :C25H33ClN2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.99DSP-1053 benzenesulfonate
CAS :<p>DSP-1053: Benzylpiperidine-based, potent SERT inhibitor (Ki=1.02nM), partial 5-HT1A receptor agonist (Ki=5.05nM), antidepressant.</p>Formule :C32H38BrNO7SCouleur et forme :SolidMasse moléculaire :660.62ATM Inhibitor-2
<p>ATM Inhibitor -2 is a potent and selective inhibitor of ATM (IC50<1 nM).</p>Formule :C26H31N7O3Couleur et forme :SolidMasse moléculaire :489.57ZBH-1205
CAS :<p>ZBH-1205, a camptothecin derivative, shows strong antitumor effects via apoptosis, outperforming cpt-11 and sn38 in topoisomerase-1 inhibition.</p>Formule :C29H31N3O8Couleur et forme :SolidMasse moléculaire :549.57Artemisiane E
CAS :<p>Artemisiane E is a potent PI3K/AKT pathway inhibitor with an IC 50 of 8.9 μM .</p>Formule :C20H22O5Couleur et forme :SolidMasse moléculaire :342.39Aurora B inhibitor 1
CAS :<p>Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 uM) with potential anticancer activity for cancer research.</p>Formule :C25H26ClF2N7O2Degré de pureté :98.37%Couleur et forme :SolidMasse moléculaire :529.97Canosimibe
CAS :<p>Canosimibe is a cholesterol absorption inhibitor</p>Formule :C44H60FN3O10Couleur et forme :SolidMasse moléculaire :809.96AM-6494
CAS :<p>AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).</p>Formule :C22H21F2N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.5PDHK-IN-3
<p>PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].</p>Formule :C17H16N2O2Couleur et forme :SolidMasse moléculaire :280.32FMK-MEA
CAS :<p>FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.</p>Formule :C21H26FN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.46BI-1388
CAS :<p>BI-1388 is a potent HCV NS3 protease inhibitor; halts replication across genotypes, including D168V/R155K mutants.</p>Formule :C41H53N7O9SCouleur et forme :SolidMasse moléculaire :819.97Anti-inflammatory agent 9
<p>Benzimidazothiazole-derived Compound 28 from tilomisole targets COX-2, has potent anti-inflammatory effects & is orally bioavailable.</p>Formule :C18H15N5O2SCouleur et forme :SolidMasse moléculaire :365.41ZK 93426 hydrochloride
CAS :<p>benzodiazepine receptor antagonist,competitive</p>Formule :C18H21ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.82Acetylpepstatin
CAS :<p>Acetylpepstatin is an inhibitor of HIV-1 protease, HIV-2 protease, aspartyl protease.</p>Formule :C33H61N5O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :703.875TD-0212
CAS :TD-0212: Oral dual antagonist for AT1 (pKi 8.9) & NEP inhibitor (pIC50 9.2).Formule :C28H34FN3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.65FXIa-IN-8
<p>FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.</p>Couleur et forme :Solid5(S),6(R)-DiHETE
CAS :<p>5(S),6(R)-DiHETE is a dihydroxy fatty acid from LTA4 hydrolysis and weak LTD4 agonist with ED50 of 1.3 μM for guinea pig ileum contraction.</p>Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47Uprosertib hydrochloride
CAS :<p>Uprosertib hydrochloride is a potent and selective inhibitor of pan-Akt (IC50: 180/328/38 nM for Akt1/Akt2/Akt3, respectively).</p>Formule :C18H17Cl3F2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :465.71DG013A
CAS :<p>DG013A inhibits ERAP1 & ERAP2 (IC50: 33 nM & 11 nM) to research autoimmune diseases & cancer.</p>Formule :C27H37N4O4PCouleur et forme :SolidMasse moléculaire :512.58HER2-IN-6
CAS :<p>HER2-IN-6, a potent HER2 inhibitor, may target wild/mutant EGFR and HER2-mediated tumors. (Patent WO2021164697A1, compound 11)</p>Formule :C26H32N8O3Couleur et forme :SolidMasse moléculaire :504.58CDK8-IN-11 hydrochloride
<p>CDK8-IN-11 HCl: potent, selective CDK8 inhibitor (IC50: 46 nM), blocks WNT/β-catenin pathway, used in colon cancer research.</p>Formule :C19H16ClF3N4O2Couleur et forme :SolidMasse moléculaire :424.8XIAP/cIAP1 antagonist-1
<p>Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.</p>Couleur et forme :SolidWW437
<p>WW437 is a histone deacetylase (HDAC) inhibitor that exhibits potent anti-breast cancer activity both in vitro and in vivo.</p>Formule :C23H27N5O4Couleur et forme :SolidMasse moléculaire :437.49(Rac)-Plevitrexed
CAS :<p>(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).</p>Formule :C26H25FN8O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.53Udifitimod
CAS :<p>Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.</p>Formule :C25H33NO2Couleur et forme :SolidMasse moléculaire :379.54Anti-inflammatory agent 10
<p>Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.</p>Formule :C17H13BrN4O3S2Couleur et forme :SolidMasse moléculaire :465.34CL656
CAS :<p>CL656 is a stimulator of interferon genes (STING) activator.</p>Formule :C20H21F2N9O9P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :695.51Oleuroside
CAS :<p>Oleuroside can protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing.</p>Formule :C25H32O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.51KDOAM-25 trihydrochloride
<p>KDOAM-25 trihydrochloride selectively inhibits KDM5 enzymes, boosts H3K4 methylation, and suppresses MM1S cell growth.</p>Formule :C15H28Cl3N5O2Couleur et forme :SolidMasse moléculaire :416.77Fusarochromanone
CAS :<p>Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium oxysporum with potent antiangiogenic, anticancer and antimalarial activities.</p>Formule :C15H20N2O4Degré de pureté :95.31% - 96%Couleur et forme :SolidMasse moléculaire :292.33RET-IN-11
<p>RET-IN-11 selectively inhibits RET (IC50: 6.20 nM), promotes apoptosis, and hinders cell proliferation and migration.</p>Formule :C27H30FN9OCouleur et forme :SolidMasse moléculaire :515.59Cryptopleurine
CAS :<p>Cryptopleurine is an inhibitor of gene products associated with cell proliferation, survival, invasion and angiogenesis. It acts by targeting the NF-κB pathway.</p>Formule :C24H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48Isoleucyl tRNA synthetase-IN-2
CAS :<p>Isoleucyl tRNA synthetase-IN-2 is a selective and potent inhibitor (Ki: 114 nM) that targets isoleucyl tRNA synthetase (IleRS).</p>Formule :C22H33N5O8SCouleur et forme :SolidMasse moléculaire :527.59PARP10/15-IN-3
<p>Compound 8a, a dual PARP10 & PARP15 inhibitor, has IC50s: PARP10 at 0.14μM & PARP15 at 0.40μM; it's cell-permeable & anti-apoptotic.</p>Formule :C12H12N2O3Couleur et forme :SolidMasse moléculaire :232.24Mopivabil
<p>Mopivabil is the angiotensin II receptor antagonist[1].</p>Formule :C14H20O3Couleur et forme :SolidMasse moléculaire :236.31CB30865
CAS :<p>CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.</p>Formule :C26H22BrN5O2Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :516.39SSR-241586
CAS :<p>SSR-241586: Neurokinin antagonist, treats depression, schizophrenia, urinary issues, emesis, IBS.</p>Formule :C32H42Cl2N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :601.61Glutamate-5-kinase-IN-1
<p>Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.</p>Formule :C20H18N2OCouleur et forme :SolidMasse moléculaire :302.37T-3764518
CAS :<p>T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).</p>Formule :C20H17F6N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.37NNC-11-1585
CAS :<p>NNC-11-1585 is an M(1) and M(2) muscarinic acetylcholine receptor (mAChR) agonist.</p>Formule :C18H19N3OSCouleur et forme :SolidMasse moléculaire :325.43(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formule :C14H10ClN3S2Couleur et forme :SolidMasse moléculaire :319.83PI3K-IN-26
CAS :<p>PI3K-IN-26 is an effective PI3K inhibitor. PI3K-IN-26 inhibits the proliferation of SU-DHL-6 cells, IC50= 36 nM.</p>Formule :C21H18N6OSCouleur et forme :SolidMasse moléculaire :402.47HBV-IN-31
CAS :<p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>Formule :C23H18ClNO6Couleur et forme :SolidMasse moléculaire :439.85MRGPRX1 agonist 3
<p>Compound 1f, a potent MRGPRX1 agonist, has an EC50 of 0.22 μM, useful for neuropathic pain studies.</p>Formule :C14H11FN2OSCouleur et forme :SolidMasse moléculaire :274.31BMS-986339
CAS :<p>BMS-986339: oral, potent FXR agonist; binds to His298/ASN287; for PBC, PSC, NASH, anti-fibrosis research.</p>Formule :C35H41F4N3O4Couleur et forme :SolidMasse moléculaire :643.71Tribenuron
CAS :<p>Tribenuron, a slow acting sulfonylurea herbicide, controls broadleaf weed.</p>Formule :C14H15N5O6SCouleur et forme :SolidMasse moléculaire :381.365-cis Carbaprostacyclin
CAS :<p>5-cis Carbaprostacyclin: a PGI2 stable analog; poor human platelet aggregation inhibitor (IC50: 2.8 μM); weakens rabbit artery relaxation (EC50: 104 μM).</p>Formule :C21H34O4Couleur et forme :SolidMasse moléculaire :350.49Antibacterial agent 69
<p>Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 μM).</p>Formule :C24H19N3O4SCouleur et forme :SolidMasse moléculaire :445.49DNA-PK-IN-6
CAS :<p>DNA-PK-IN-6 inhibits DNA-PKcs, disrupting tumor DNA repair and triggering apoptosis; enhances radiotherapy and targets various tumors (WO2021197159A1).</p>Formule :C19H21N7OCouleur et forme :SolidMasse moléculaire :363.42Combretastatin A1 phosphate
CAS :<p>Combretastatin A1 phosphate: potent anti-angiogenic and tumor vascular disruptor, with research potential in pancreatic neuroendocrine tumors.</p>Formule :C18H22O12P2Couleur et forme :SolidMasse moléculaire :492.31Polvitolimod
CAS :<p>Polvitolimod is a TLR7 agonist used to treat infectious disease and cancer.</p>Formule :C13H14FN5O4Couleur et forme :SolidMasse moléculaire :323.28SS-RJW100
<p>SS-RJW100 is an enantiomer of RJW100 targeting LRH-1, SF-1, enhances Tif2 interaction, and disrupts LRH-1 networks with lowered stability.</p>Formule :C28H34OCouleur et forme :SolidMasse moléculaire :386.57LGB-321 HCl
CAS :<p>LGB-321: potent, selective PIM kinase inhibitor, active against PIM2, halts diverse blood cancers' growth, orally effective in mice.</p>Formule :C23H23ClF3N5O2Couleur et forme :SolidMasse moléculaire :493.91Nedocromil sodium
CAS :<p>Nedocromil sodium is a pharmacologic stabilizer of mast cells, has been shown to normalize cytokine levels and attenuate cardiac remodeling.</p>Formule :C19H17NNaO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :394.335Pelecopan
CAS :<p>Pelecopan (BCX9930), an oral complement factor D inhibitor, prevents hemolysis in PNH (IC50=14.3 nM).</p>Formule :C23H19FN2O4Couleur et forme :SolidMasse moléculaire :406.41M826
<p>M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity in</p>Formule :C28H45N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.7Menin-MLL inhibitor 26
CAS :<p>Menin-MLL inhibitor 26: Active reference, inhibits cell growth, used in leukemia research.</p>Formule :C27H29F3N6O3SCouleur et forme :SolidMasse moléculaire :574.62GPX100 HCl
CAS :<p>GPX-100, a non-cardiotoxic doxorubicin analog, intercalates DNA and inhibits replication, repair, and protein synthesis.</p>Formule :C27H32ClNO10Couleur et forme :SolidMasse moléculaire :566NTPDase-IN-2
CAS :<p>NTPDase-IN-2 inhibits h-NTPDase-2/-8 (IC50: 0.04, 2.27 µM), non-competitive for h-NTPDase-1/-2 (Km: 74 µM); useful in cancer, immune, bacterial research.</p>Formule :C24H20FN3OS2Couleur et forme :SolidMasse moléculaire :449.56KAG-308
CAS :<p>KAG-308: selective EP4 agonist; Ki: 2.57 nM, EC50: 17 nM; suppresses colitis, promotes mucosal healing, inhibits TNF-α.</p>Formule :C24H30F2N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.52CAII-IN-2
<p>CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.</p>Formule :C18H19BrN4SCouleur et forme :SolidMasse moléculaire :403.34(S)-Seco-Duocarmycin SA
CAS :<p>(S)-Seco-Duocarmycin SA is a DNA alkylating agent and antibiotic with potent antitumor activity that can be used to synthesize ADC compounds.</p>Formule :C25H24ClN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.93
