Inhibiteurs

SK-575-NEG is a methylated form of SK-575, binds PARP1 (IC50: 2.64 nM), but doesn't induce PARP1 degradation up to 1 μM in cells.

SIAIS164018, a PROTAC-derived ALK/EGFR degrader from Brigatinib, has IC50s of 2.5 & 6.6 nM; it hinders cancer cell movement and promotes apoptosis.

Compound 32a: PROTAC BRD4 Degrader-6, IC50 = 2.7 nM, degrades BRD4, halts BxPC3 pancreatic cancer cell growth, induces apoptosis for research.

1-Oleoyl Lysophosphatidic Acid (1-Oleoyl LPA) is a biologically active phospholipid that can be used to study cancer and atherosclerosis.

VH032-PEG3-acetylene: a VHL ligand-linker for PROTACs, combines VH032 with PEG3-acetylene.

FGFR-IN-1 targets FGFR1-3 with IC50 <100 nM. (US20130338134A1, ex 219)

Anticancer agent 11 suppresses angiogenesis and induces DNA cross-links for broad-spectrum efficacy.

Elamipretide acetate (MTP 131), a small tetrapeptide, targets mitochondria to reduce toxic species and stabilize cardiolipin.

α-conotoxin GI, a conopeptide isolated from the venom of the cone snail Conus geographus, is a competitive antagonist of the muscle-type nicotinic acetylcholine

Mouse IgG3 kappa Isotype Control is a monoclonal antibody serving as an isotype control specifically for mouse IgG3κ antibodies.