Inhibiteurs

Spiratisanin A is a natural product from Spiraea japonica.

SHP2 degrader-1: highly efficient, induces SHP2 degradation & cell apoptosis, shows promise in SHP2-related disease research.

Contezolid acefosamil (MRX-4), oral prodrug of Contezolid (MRX-I), treats multidrug-resistant Gram-positive bacteria, including MRSA.

Nutlin carboxylic acid is a Nutlin 3-based MDM2 ligand; used with a linker to create PROTACs.

HJM-561 is a potent and selective EGFR PROTAC with oral bioavailability, capable of overcoming osimertinib-resistant EGFR triple mutations and demonstrating

Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).

NT 2 Toxin is a useful organic compound for research related to life sciences. The catalog number is T124258 and the CAS number is 76348-84-0.

(5R)-Platyphyllone has a wide range of applications in life science related research.

IDO1-IN-20 is an enzyme that catalyzes the oxidative metabolism of tryptophan. It can immunosuppress tumors in the tumor microenvironment.

Microcystin-LY, from Microcystis aeruginosa, is a heptapeptide toxin that triggers oxidative stress by activating the Nrf2 pathway, most effective at 3μM.

PROTAC MDM2 Degrader-3 uses PROTAC tech to efficiently break down MDM2 with a potent inhibitor and E3 ligase ligand.