Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.657 produits)
- Apoptose(6.058 produits)
- Cycle cellulaire/point de contrôle(4.657 produits)
- Chromatine/Épigénétique(2.354 produits)
- Signalisation du cytosquelette(1.460 produits)
- Altération de l'ADN/réparation de l'ADN(2.908 produits)
- Endocrinologie/Hormones(3.601 produits)
- Enzyme(3.655 produits)
- GPCR/G-Protéine(8.703 produits)
- Immunologie et Inflammation(3.737 produits)
- Virus de la grippe(298 produits)
- Signalisation JAK/STAT(403 produits)
- Signalisation MAPK(1.227 produits)
- Transporteur membranaire/Canal ionique(2.922 produits)
- Métabolisme(9.881 produits)
- Microbiologie/Virologie(7.303 produits)
- Neuroscience(10.209 produits)
- Autres inhibiteurs(36.770 produits)
- Oxydation-Réduction(42 produits)
- Signalisation PI3K/Akt/mTOR(1.430 produits)
- Protéases/Protéasome(1.669 produits)
- Cellules souche et Dérivés(828 produits)
- Tyrosine Kinase/Adaptateurs(2.042 produits)
- Ubiquitination(1.681 produits)
Affichez 16 plus de sous-catégories
66609 produits trouvés pour "Inhibiteurs"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
IRE1α kinase-IN-4
CAS :<p>IRE1α kinase-IN-4 (compound 6) is a potent inhibitor of IRE1α, exhibiting a Ki value of 140 nM. It acts as an ATP-competitive ligand for IRE1α [1].</p>Formule :C29H31N7O2Couleur et forme :SolidMasse moléculaire :509.6PTP1B-IN-21
PTP1B-IN-21 inhibits PTP1B (IC50=1.56μM) selectively over TCPTP, a type 2 diabetes target.Formule :C22H22O11Couleur et forme :SolidMasse moléculaire :462.4HDAC-IN-9
HDAC-IN-9, a dual tubulin/HDAC inhibitor, impedes A549 cell invasion/migration and shows strong anti-tumor/angiogenic effects.Formule :C33H38N2O4Couleur et forme :SolidMasse moléculaire :526.67FtsZ-IN-4
<p>FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).</p>Formule :C21H16ClF2NO2Couleur et forme :SolidMasse moléculaire :387.81Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formule :C21H19F2N7O3S2Couleur et forme :SolidMasse moléculaire :519.55Antitrypanosomal agent 5
Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).Formule :C30H30N6O4SCouleur et forme :SolidMasse moléculaire :570.66SphK1-IN-1
<p>SphK1-IN-1: SphK1 ATPase inhibitor, IC50=2.48 μM, potential for cancer research.</p>Formule :C22H22N6O2Couleur et forme :SolidMasse moléculaire :402.45Triphen diol
CAS :Triphen diol, a phenol diol, fights pancreatic cancer & cholangiocarcinoma, inducing apoptosis via caspase-dependent & -independent paths.Formule :C22H20O4Couleur et forme :SolidMasse moléculaire :348.39Marizomib
CAS :Marizomib is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L, CT-T-laspase-like, and trypsin-like 20S proteasomes.Cost-effective and quality-assured.Formule :C15H20ClNO4Degré de pureté :98.03% - 99.41%Couleur et forme :SolidMasse moléculaire :313.78Anticancer agent 35
Compound 10, a sulfonylurea, inhibits A549, A431, PACA2 cells with IC50s: 18.1, 4.0, 18.9 μg/mL.Formule :C15H13N3O3S3Couleur et forme :SolidMasse moléculaire :379.48MsbA-IN-2
<p>MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).</p>Formule :C23H19Cl2NO3Couleur et forme :SolidMasse moléculaire :428.31α-Amylase-IN-1
CAS :α-Amylase-IN-1 is an α-Amylase inhibitor (IC50: 0.5509 μM).Formule :C18H18N2O3Degré de pureté :99.92%Couleur et forme :SoildMasse moléculaire :310.35Plm IV inhibitor-2
CAS :"Plm IV inhibitor-2: Potent for Plm IV (IC50=24nM), affects Plm II/Plm I; malaria research compound."Formule :C39H54N4O4Couleur et forme :SolidMasse moléculaire :642.87ERRγ agonist-1
ERRγ agonist-1 can be used in neuropsychological disorders research.Formule :C17H21N5OCouleur et forme :SolidMasse moléculaire :311.38ZK 93426 hydrochloride
CAS :benzodiazepine receptor antagonist,competitiveFormule :C18H21ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.82PXS-5153A monohydrochloride
CAS :<p>PXS-5153A is an oral, fast-acting LOXL2/3 inhibitor with IC50 <40 nM for LOXL2 and 63 nM for LOXL3, potentially treating fibrosis.</p>Formule :C20H25Cl2FN4O2SDegré de pureté :98%Couleur et forme :Odour SolidMasse moléculaire :475.41Hoe 892
CAS :<p>Hoe 892 is a stable thia-thimo-analogue of prostacyclin and acts as a platelet aggregation inhibitor.</p>Formule :C20H33NO4SCouleur et forme :SolidMasse moléculaire :383.55Aplaviroc hydrochloride
CAS :<p>Aplaviroc, a potent CCR5 inhibitor, binds selectively, blocking HIV entry and specific monoclonal antibody attachment in vitro.</p>Formule :C33H44ClN3O6Couleur et forme :SolidMasse moléculaire :614.17Glycyl H-1152 hydrochloride
CAS :<p>Glycyl-H-1152 is a potent ROCK-II inhibitor (IC50=11.8 nM) with high selectivity over CaMKII, PKG, Aurora A, PKA, and PKC. Better than Y-27632 and HA-1077.</p>Formule :C18H26Cl2N4O3SCouleur et forme :SolidMasse moléculaire :449.39Anticancer agent 29
<p>Compound E/Z-6f, anticancer, IC50: CDK2 (0.054 μM), CDK1 (0.127 μM), CDK4 (0.129 μM), CDK6 (0.396 μM).</p>Formule :C22H15ClFNOCouleur et forme :SolidMasse moléculaire :363.81SHR0687
CAS :<p>SHR0687: potent KOR agonist, selective, favorable PK, effective in rat pain model, minimal BBB penetration, less CNS side effects.</p>Formule :C39H60N8O5Couleur et forme :SolidMasse moléculaire :720.94Human enteropeptidase-IN-2
<p>Human enteropeptidase-IN-2 is a potent inhibitor of enteropeptidase (enteropeptidase) and can be used in anti-obesity studies.</p>Formule :C20H19F3N4O7Couleur et forme :SolidMasse moléculaire :484.38CXCR2 antagonist 4
<p>CXCR2 antagonist 4 inhibits CXCR2 (IC50: 0.13 μM) and CXCL8-induced calcium rise (IC50: 27 μM), promising for cancer research.</p>Formule :C15H14F2N4OS2Couleur et forme :SolidMasse moléculaire :368.42CBR Agonist-2
<p>CBR Agonist-2: CB1 receptor agonist, EC50 - 960 nM, Ki - 970 nM, useful for hCB1R-related disease research.</p>Formule :C27H27FN4OCouleur et forme :SolidMasse moléculaire :442.53SARS-CoV-2-IN-23
SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].Formule :C21H22N2OCouleur et forme :SolidMasse moléculaire :318.41Urease-IN-1
<p>Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).</p>Formule :C17H12BrFN4O2SCouleur et forme :SolidMasse moléculaire :435.27AKR1C3-IN-5
<p>AKR1C3-IN-5 inhibits AKR1C3, key in prostate/breast cancers, with MCF-7 cell IC50 of 9.6 μM.</p>Formule :C34H44N2O7Couleur et forme :SolidMasse moléculaire :592.72URAT1 inhibitor 2
<p>URAT1 inhibitor 2: oral URAT1/CYP blocker, IC50 of 1.36μM (URAT1), 16.97μM (CYP1A2), 5.22μM (CYP2C9); potential gout treatment.</p>Formule :C21H18BrN3O2SCouleur et forme :SolidMasse moléculaire :456.36Epiderstatin
CAS :<p>Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.</p>Formule :C15H20N2O4Couleur et forme :SolidMasse moléculaire :292.33AAA-10 formic
<p>AAA-10 formic is an orally active inhibitor of intestinal bacterial bile salt hydrolase (BSH) against B.</p>Formule :C26H43FO7SCouleur et forme :SolidMasse moléculaire :518.68MCTR3
CAS :MCTR3, derived from DHA via maresin 1 in macrophages, hastens tissue healing and reduces inflammation and eicosanoids post-E. coli infection in mice.Formule :C25H37NO5SCouleur et forme :SolidMasse moléculaire :463.63Elacestrant S enantiomer
<p>Elacestrant S enantiomer is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively.</p>Formule :C30H38N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.63Sargachromanol E
CAS :<p>Sargachromanol E is a compound isolated from the marine brown alga, Sargassum horneri. It has been studied for its inhibitory effect on skin ageing.</p>Formule :C27H40O4Couleur et forme :SolidMasse moléculaire :428.6PF 03709270
CAS :PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.Formule :C19H27NO7S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.61WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Formule :C24H23F6N5O5Degré de pureté :99.52%Couleur et forme :SoildMasse moléculaire :575.46PAIR2
CAS :PAIR2 is a selective IRE1α RNase partial antagonist, blocking its ATP site and preventing KIRA from hindering XBP1 splicing.Formule :C27H26F4N6O3SCouleur et forme :SolidMasse moléculaire :590.59Triciferol
CAS :<p>Triciferol is a VDR agonist and HDAC antagonist with 1,25D-like potency, affecting gene targets and tubulin, and shows anti-cancer effects in vitro. IC50=87nM.</p>Formule :C26H39NO4Couleur et forme :SolidMasse moléculaire :429.591NPR-C activator 1
CAS :NPR-C activator 1 is an activator of the natriuretic peptide receptor C (NPR-C), which can be used to study cardiovascular diseases.Formule :C18H24N6O3Degré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :372.42WM382
CAS :<p>WM382, a potent dual PMIX/X inhibitor, has IC50s of 1.4 nM/0.03 nM and effective against various malaria stages.</p>Formule :C29H36N4O4Couleur et forme :SolidMasse moléculaire :504.62ETP-47037
CAS :ETP-47037: strong PI3Kα inhibitor (IC50: 0.99 nM), also targets PI3Kβ, δ, γ; may protect telomeres.Formule :C20H27N9O3SCouleur et forme :SolidMasse moléculaire :473.5518-Deoxyherboxidiene
CAS :<p>18-Deoxyherboxidiene (RQN-18690A) inhibits angiogenesis, targeting SF3b in U2 snRNP spliceosome, affects HUVEC, useful for cancer research.</p>Formule :C25H42O5Couleur et forme :SolidMasse moléculaire :422.615(R)-Lipoxin A4
CAS :<p>Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and</p>Formule :C20H32O5Couleur et forme :SolidMasse moléculaire :352.47Exicorilant
CAS :Exicorilant is a selective oral GR antagonist (Ki: 7 nM) that may reduce obesity, glucose intolerance, & dyslipidemia.Formule :C26H23F4N7O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :589.56NOS-IN-2
<p>NOS-IN-2: potent, selective imidamide NOS inhibitor, IC50=20μM for iNOS, spares eNOS, low toxicity, useful in inflammation research.</p>Formule :C18H20F3N3O2Couleur et forme :SolidMasse moléculaire :367.37CJ-887
CAS :<p>CJ-887 is a STAT3 inhibitor.</p>Formule :C34H45N6O10PCouleur et forme :SolidMasse moléculaire :728.73SR121566A
CAS :SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).Formule :C20H25N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.51J-104132
CAS :J-104132: potent human ETA/B antagonist; Ki: ETA=0.034nM, ETB=0.104nM; prevents ET-1 effects, ED50 i.v.=0.045mg/kg, p.o.=0.35mg/kg.Formule :C31H33NO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.60Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Formule :C20H18N2OCouleur et forme :SolidMasse moléculaire :302.37ICA-105665
CAS :ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.Formule :C19H15F2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.34LY 178210
CAS :LY 178210 is a 5-hydroxytryptamine receptor agonist.Formule :C18H25N3OCouleur et forme :SolidMasse moléculaire :299.41RET-IN-11
RET-IN-11 selectively inhibits RET (IC50: 6.20 nM), promotes apoptosis, and hinders cell proliferation and migration.Formule :C27H30FN9OCouleur et forme :SolidMasse moléculaire :515.59hTrkA-IN-2
<p>hTrkA-IN-2 is a selective hTrkA metamorphosis inhibitor (IC50: 3.9 nM).</p>Formule :C24H22F3N5O3Couleur et forme :SolidMasse moléculaire :485.46TGR5 Receptor Agonist 3
CAS :<p>TGR5 Receptor Agonist 3 is a GPBAR1 agonist with EC50 of 16.4 nM (hTGR5) & 209 nM (mTGR5), ensures gallbladder safety and reduces filling.</p>Formule :C29H27N3O6Couleur et forme :SolidMasse moléculaire :513.54Leukotriene B4 dimethyl amide
CAS :LTB4 dimethyl amide: inhibits human neutrophil degranulation and rat lysozyme release; antagonizes LTB4 receptor on guinea pig lung membranes (Ki = 130 nM).Formule :C22H37NO3Couleur et forme :SolidMasse moléculaire :363.53Antiproliferative agent-4
<p>Antiproliferative agent-4 suppresses cancer cell growth with low toxicity, inhibits tumors in mice, and induces apoptosis in EC109 cells.</p>Formule :C29H35ClO8Couleur et forme :SolidMasse moléculaire :547.04KMN-80
CAS :<p>KMN-80 is a potent, selective EP4 agonist with IC50 3 nM, spurring osteoblast differentiation, and showing in vivo bone repair efficacy.</p>Formule :C21H33NO4Couleur et forme :SolidMasse moléculaire :363.49Mesulergine
CAS :<p>Mesulergine is metabolized into dopaminergic agonists.</p>Formule :C18H26N4O2SCouleur et forme :SolidMasse moléculaire :362.49CS-003 HCl
CAS :<p>CS-003 HCl is a TNRA - triple neurokinin receptor antagonist.</p>Formule :C34H39Cl3N2O6SCouleur et forme :SolidMasse moléculaire :710.1IT-066 HCl
CAS :<p>IT-066 HCl is a histamine H2 receptor antagonist.</p>Formule :C19H25ClN4O3Couleur et forme :SolidMasse moléculaire :392.88MEIS-IN-2
MEIS-IN-2 is an inhibitor of MEIS1. MEIS-IN-2 can be used in studies of cardiac regeneration and haematopoietic stem cell (HSC) regulation.Formule :C23H21ClN2O4Couleur et forme :SolidMasse moléculaire :424.88MEIS-IN-3
MEIS-IN-3 is a potent inhibitor of MEIS.Formule :C25H26N2O4Couleur et forme :SolidMasse moléculaire :418.48GSK-3β inhibitor 7
GSK-3β inhibitor 7 is a GSK-3β inhibitor (IC50: 5.25 μM).Formule :C27H23BrN4O2SCouleur et forme :SolidMasse moléculaire :547.47Minnelide free acid
CAS :Minnelide treats pancreatic cancer, hinders androgen-related prostate growth, shrinks tumors, and improves survival.Formule :C21H27O10PCouleur et forme :SolidMasse moléculaire :470.41CE-2072
CAS :CE-2072 is a synthetic host serine proteases inhibitor.Formule :C33H41N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.71RGT-068A
CAS :RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .Formule :C17H16ClN9O2Couleur et forme :SolidMasse moléculaire :413.82PARP1/BRD4-IN-2
PARP1/BRD4-IN-2, a potent inhibitor of PARP1 and BRD4, halts cell cycle, triggers apoptosis, and has antitumor effects on TNBC.Formule :C25H20N4O4Couleur et forme :SolidMasse moléculaire :440.45Lobaric acid
CAS :<p>Lobaric acid, from Stereocaulon lichen, has antioxidant and anticancer properties, inhibits PTP1B and 12(S)-LOX, and reduces TMV lesions in plants.</p>Formule :C25H28O8Couleur et forme :SolidMasse moléculaire :456.48DJT06001
CAS :DJT06001 is a selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding.Formule :C21H20ClN3O5SCouleur et forme :SolidMasse moléculaire :461.92Deltasonamide 2 hydrochloride
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.Formule :C30H40Cl2N6O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :683.71Tzc 5665
CAS :<p>Tzc 5665 is a pyridazinone derivative with vasodilatory and beta-adrenergic blocking activities and type III phosphodiesterase inhibitory action.</p>Formule :C31H38ClN5O7Couleur et forme :SolidMasse moléculaire :628.12OUN58101
CAS :<p>OUN58101, also MDK-8101/BI-D, is an RSV L-protein inhibitor with no formal name, first reported in patent WO 2005042530.</p>Formule :C32H36N6O6Couleur et forme :SolidMasse moléculaire :600.66Murizatoclax
CAS :AMG 397 is an oral MCL1 inhibitor .Formule :C42H57ClN4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :765.44DH376
CAS :<p>DH376 inhibits DAGLα in a time and dose dependent manner in mouse brain. DH376 shows picomolar activity.</p>Formule :C31H28F2N4O3Couleur et forme :SolidMasse moléculaire :542.58Samuraciclib hydrochloride hydrate
<p>Samuraciclib (CT7001) is a potent oral CDK7 inhibitor (IC50: 41 nM) with anti-breast cancer properties.</p>Formule :C22H35ClN6O3Couleur et forme :SolidMasse moléculaire :521.7MsbA-IN-4
<p>MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).</p>Formule :C23H18Cl2FN5OCouleur et forme :SolidMasse moléculaire :470.33Anticancer agent 28
Anticancer agent 28 is 50x more potent than Oridonin, IC50 of 0.09 μM against K562; effective in H22 mouse tumors.Formule :C28H33NO6Couleur et forme :SolidMasse moléculaire :479.56Hit 1
<p>Hit 1 is an activator of insulin-degrading enzymes (IDE) (EC50: 5.5 μM) and reduces glucose-stimulated insulin secretion.</p>Formule :C22H24N4O3S2Couleur et forme :SolidMasse moléculaire :456.58Homodestcardin
CAS :<p>Homodestcardin: cyclic depsipeptide from T. roseum with immunosuppressant properties; inhibits mouse T cell proliferation.</p>Formule :C32H55N5O7Couleur et forme :SolidMasse moléculaire :621.81TH-6
TH-6, a potent HDAC inhibitor (IC50: HDAC1-0.115, 2-0.135, 3-0.242, 6-0.138, 8-2.120 μM), blocks cell migration, invasion, and has anti-tumor properties.Formule :C22H24FN3O5Couleur et forme :SolidMasse moléculaire :429.44H 218-54
CAS :<p>H 218-54 is a renin inhibitor.</p>Formule :C37H56N2O5SCouleur et forme :SolidMasse moléculaire :640.92Cathepsin K inhibitor 2
CAS :Cathepsin K inhibitor 2 targets CTSK gene, may treat osteoporosis and osteoarthritis, detailed in patent WO2021147882A1.Formule :C30H33F4N5O3Couleur et forme :SolidMasse moléculaire :587.61L-365260 hemihydrate
<p>L-365260 hemihydrate: selective oral CCK-B/gastrin blocker, Ki=1.9/2.0 nM, competes with guinea pig receptors.</p>Formule :C24H24N4O3Couleur et forme :SolidMasse moléculaire :407.47Cav 3.2 inhibitor 2
Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.Formule :C32H37F2N3OCouleur et forme :SolidMasse moléculaire :517.65PF-06380101
CAS :<p>PF-06380101, a potent auristatin analog and Dolastatin 10 derivative, shows strong anti-tumor activity and unique ADME attributes.</p>Formule :C39H62N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :743.01ZIKV-IN-5
ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.Formule :C36H45NO4SiCouleur et forme :SolidMasse moléculaire :583.83Acyline
CAS :<p>Acyline, a GnRH antagonist, suppresses gonadotropins and testosterone in animals and maintains the effect for 2 weeks in men with one dose.</p>Formule :C80H102ClN15O14Couleur et forme :SolidMasse moléculaire :1533.21hCAII-IN-5
CAS :hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].Formule :C29H18N2O7Couleur et forme :SolidMasse moléculaire :506.46TP-030-2
CAS :<p>TP-030-2 is a RIPK1 inhibitor (human K i =0.43 nM ; mouse IC 50 =100 nM) .</p>Formule :C23H21BrN4O3Couleur et forme :SolidMasse moléculaire :481.34COX-2-IN-29
<p>COX-2-IN-29 is a selective inhibitor of orally active COX-2 (IC50: 0.005 μM).</p>Formule :C22H23FN2O6S2Couleur et forme :SolidMasse moléculaire :494.56(S)-MALT1-IN-5
CAS :<p>(S)-MALT1-IN-5: Potent MALT1 protease inhibitor, may help in abnormal T/B-cell signalling and MALT1-linked diseases.</p>Formule :C17H17ClF2N6O3Couleur et forme :SolidMasse moléculaire :426.80ALK-IN-23
ALK-IN-23 inhibits ALK (IC50: 1.6-0.71 nM), hinders cancer cell spread, forms colonies in vitro, and reduces tumors in mice with low toxicity.Formule :C26H29ClN8O3SCouleur et forme :SolidMasse moléculaire :569.08Antitubercular agent-15
Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.Formule :C21H29FN2Couleur et forme :SolidMasse moléculaire :328.47BPTF-IN-BZ1
<p>BPTF-IN-BZ1 is a BPTF inhibitor that possesses a high potency with a Kd of 6.3 nM.</p>Formule :C13H15ClN4OCouleur et forme :SolidMasse moléculaire :278.74AKT-IN-10
CAS :AKT-IN-10, a potent AKT inhibitor, has potential for breast and prostate cancer research, impacting cell growth and survival pathways.Formule :C26H34ClN5O2Couleur et forme :SolidMasse moléculaire :484.03MMSET-IN-1
CAS :MMSET-IN-1 is an inhibitor of multiple myeloma SET domain (MMSET, aka NSD2/WHSC1) .Formule :C18H29N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :423.47Antiangiogenic agent 2
<p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>Formule :C26H26FN3O4Couleur et forme :SolidMasse moléculaire :463.5GSK340
<p>GSK340 is a BET inhibitor.</p>Formule :C26H31N3O2Couleur et forme :SolidMasse moléculaire :417.55KR-67607
CAS :KR-67607, or NTX-101, is a novel 11β-HSD1 inhibitor that protects against eye injury by reducing cortisol and preserving eye structures.Formule :C24H29Cl2F3N4O4SCouleur et forme :SolidMasse moléculaire :597.48BMS-901715
CAS :BMS-901715 is an effective and selective inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50: 3.3 nM).Formule :C22H28N10ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.52EGFR-IN-35
CAS :EGFR-IN-35, an acrylamide-based EGFR inhibitor, shows promise for EGFR mutation-related cancers like NSCLC.Formule :C25H24ClN7O2Couleur et forme :SolidMasse moléculaire :489.96ATUX-1215
CAS :<p>ATUX-1215, a protein phosphatase 2A (PP2A) activator, diminishes the phosphorylation of ERK, p38, JNK, and Akt, as well as decreases the secretion of IL-12p70,</p>Formule :C27H24F5NO4SCouleur et forme :SolidMasse moléculaire :553.54MEIS-IN-1
CAS :<p>MEIS-IN-1 is a potent MEIS inhibitor that induces the expansion of hematopoietic stem cells in mice and humans.</p>Formule :C24H21F3N2O4Couleur et forme :SolidMasse moléculaire :458.43EGFR/HER2-IN-4
EGFR/HER2-IN-4: oral, irreversible dual EGFR inhibitor (IC50: 0.6 nM), targets L858R/T790M mutations, potent anti-lung cancer effects in vivo.Couleur et forme :SolidCAII-IN-1
CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.Formule :C19H21FN4SCouleur et forme :SolidMasse moléculaire :356.46AG-7404
CAS :AG-7404: strong protease inhibitor, fights poliovirus, EC50 0.080-0.674 μM, effective on V-073-resistant strains.Formule :C26H29N5O7Couleur et forme :SolidMasse moléculaire :523.54Methysergide maleate
CAS :Methysergide prevents migraines/cluster headaches; treats serotonin syndrome, carcinoid-induced diarrhea; risk of fibrosis limits use.Formule :C25H31N3O6Degré de pureté :98%Couleur et forme :White To Off-WhiteMasse moléculaire :469.54SCO-792
SCO-792: potent, reversible oral enteropeptidase inhibitor, with slow in vitro dissociation and in vivo protein digestion blocking.Formule :C22H22N4O8·xH2OCouleur et forme :SolidCryptopleurine
CAS :Cryptopleurine is an inhibitor of gene products associated with cell proliferation, survival, invasion and angiogenesis. It acts by targeting the NF-κB pathway.Formule :C24H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48CLK1/4-IN-1
CLK1/4-IN-1 inhibits Clk1/4 (IC50: 9.7/6.6 nM), curbing T24 cell growth (GI50: 1.1 μM). Potential cancer research tool.Formule :C18H14ClNO4SCouleur et forme :SolidMasse moléculaire :375.83Homopteroic Acid
CAS :Homopteroic Acid, a precursor to Homofolic Acid, inhibits L1210 mouse leukemia growth by targeting folate uptake.Formule :C15H14N6O3Couleur et forme :SolidMasse moléculaire :326.31LPM4870108
<p>LPM4870108: Potent, oral pan-Trk inhibitor, selective over ALK, with anti-tumor effects. TrkC IC50=0.2nM, TrkA IC50=2.4nM.</p>Formule :C20H19FN6O3Couleur et forme :SolidMasse moléculaire :410.4Pibrozelesin
CAS :Pibrozelesin, a water-soluble duocarmycin B2 derivative, binds AT-rich DNA, blocking replication and inducing cell death.Formule :C32H36BrN5O8Couleur et forme :SolidMasse moléculaire :698.56CYP2C19-IN-1
<p>CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.</p>Formule :C26H26N2O6SCouleur et forme :SolidMasse moléculaire :494.56MK-2748
CAS :MK-2748 is an inhibitor of NS3 protease, hepatitis C virus.Formule :C42H56N6O10SCouleur et forme :SolidMasse moléculaire :836.99KRAS G12D inhibitor 12
KRAS G12D inhibitor 12 targets Ras protein for cancer research. (Patent WO2021108683A1, Compound 134)Formule :C23H21ClFN5O3Couleur et forme :SolidMasse moléculaire :469.9FTO-IN-4
CAS :FTO-IN-4 is a potent and selective inhibitor of adiposity and obesity-associated protein (FTO).Formule :C22H16Cl2N6O6Couleur et forme :SolidMasse moléculaire :531.31Apoptosis inducer 5
<p>Apoptosis Inducer 5, a lignan enantiomer extracted from Crataegus pinnatifida, demonstrates cytotoxic properties through inducing apoptosis and autophagy in</p>Formule :C23H26O7Couleur et forme :SolidMasse moléculaire :414.45NA 0362
CAS :NA 0362 is a derivative of SF 2370 that inhibits smooth muscle contraction.Formule :C28H26N4O4Couleur et forme :SolidMasse moléculaire :482.53AVE-1330A free acid
CAS :AVE-1330A free acid is a broad-spectrum non-beta-lactam beta-lactamase inhibitor.Formule :C7H11N3O6SCouleur et forme :SolidMasse moléculaire :265.24PF-446687
CAS :PF-446687 is a highly selective MC4 receptor (MC4R) agonist.Formule :C28H37ClF2N2O2Couleur et forme :SolidMasse moléculaire :507.06PTP1B-IN-19
<p>PTP1B-IN-19, a benzimidazole, selectively inhibits protein tyrosine phosphatase 1B with a Ki of 23.3 μM, potential for type 2 diabetes research.</p>Formule :C26H19N3O4SCouleur et forme :SolidMasse moléculaire :469.51EGFR-IN-23
CAS :EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.Formule :C36H44BrN10O3PCouleur et forme :SolidMasse moléculaire :775.68Gougerotin
CAS :Gougerotin is an inhibitor of protein synthesis.Formule :C16H25N7O8Couleur et forme :SolidMasse moléculaire :443.41PRMT5-IN-18
CAS :PRMT5-IN-18 (Compound 002) is a potent inhibitor of PRMT5 and can be used in the study of PRMT5-mediated diseases, such as tumours.Formule :C32H42N4O4Couleur et forme :SolidMasse moléculaire :546.70HBV-IN-18
HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).Formule :C17H15F6N5O2Couleur et forme :SolidMasse moléculaire :435.32PTP1B-IN-17
PTP1B-IN-17, a benzimidazole derivative, inhibits PTP1B (Ki: 30.2 μM) and may help study type 2 diabetes.Formule :C26H19N3O4SCouleur et forme :SolidMasse moléculaire :469.51Ivaltinostat formic
Ivaltinostat (CG-200745) is an oral panHDAC inhibitor, inducing apoptosis and enhancing cancer drug sensitivity.Formule :C25H35N3O6Couleur et forme :SolidMasse moléculaire :473.56EBOV-GP-IN-1
EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).Formule :C25H40ClN3O2Couleur et forme :SolidMasse moléculaire :450.06Ibafloxacine
CAS :Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect againstFormule :C15H14FNO3Degré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :275.27Colistin adjuvant-2
Colistin adjuvant-2 is a compound that acts as a potentiation agent for colistin, effectively enhancing its activity against Gram-negative bacteria [1].Formule :C14H7Cl2F3N2OCouleur et forme :SolidMasse moléculaire :347.12VEGFR-2-IN-14
VEGFR-2-IN-14 (Compound 5) is a potent inhibitor of VEGFR-2, which inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.Formule :C24H23N3O3SCouleur et forme :SolidMasse moléculaire :433.52BDZ-h
CAS :<p>BDZ-h inhibits both closed/open states of all 4 homomeric & 2 GluA2R-complex AMPA receptors.</p>Formule :C21H21N5O3SCouleur et forme :SolidMasse moléculaire :423.49CHK1-IN-2
CAS :CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).Formule :C20H22N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.48PPARγ agonist 1
<p>PPARγ agonist 1 is a potent agonist of PPARγ that efficiently activates hPPARγ without causing full agonism, thereby avoiding adverse effects.</p>Formule :C34H39NO3Couleur et forme :SolidMasse moléculaire :509.68FLT3-IN-13
<p>FLT3-IN-13 inhibits topoisomerase II/FLT3 in leukemia with IC50 of 2.26 μM, causes G2/M arrest, and promotes apoptosis.</p>Formule :C20H14N4O2Couleur et forme :SolidMasse moléculaire :342.35HBV-IN-19 TFA
CAS :<p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>Formule :C26H31F3N2O8Couleur et forme :SolidMasse moléculaire :556.5317β-HSD1-IN-1
17β-HSD1-IN-1 (Compound 1) can be used in the non-small cell lung cancer (NSCLC) research.Formule :C21H21NO3Couleur et forme :SolidMasse moléculaire :335.4NCATS-SM4487
CAS :NCATS-SM4487 is a highly selective inhibitor of GALK1 (IC50: 0.05 μM).Formule :C25H24ClFN8O2Couleur et forme :SolidMasse moléculaire :522.96DNA crosslinker 3 dihydrochloride
CAS :<p>Compound 1: a DNA minor groove binder with 1.4°C ΔTm; useful in cancer research.</p>Formule :C15H22Cl2N8OCouleur et forme :SolidMasse moléculaire :401.29Riminkefon
CAS :<p>Riminkefon is a kappa opioid receptor agonist .</p>Formule :C38H57N7O6Couleur et forme :SolidMasse moléculaire :707.9PDHK-IN-3
PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].Formule :C17H16N2O2Couleur et forme :SolidMasse moléculaire :280.32KRAS G12D inhibitor 3
CAS :KRAS G12D Inhibitor 3, a compound targeting the KRAS G12D mutation, demonstrates potent antitumor efficacy with an inhibitory concentration (IC50) of less thanFormule :C34H31ClF3N5O2Couleur et forme :SolidMasse moléculaire :634.09(R)-FL118
CAS :FL118 inhibits human survivinion expression and activates tumor suppressor p53 as a MOA in p53 wild-type cancer cells.Formule :C21H16N2O6Couleur et forme :SolidMasse moléculaire :392.36PI4KIIIbeta-IN-11
CAS :PI4KIIIbeta-IN-11 is a PI4KIIIβ inhibitor (mean pIC50=9.1) that can be used to study diseases caused by RNA viruses and Plasmodium falciparum.Formule :C33H39N7O3Couleur et forme :SolidMasse moléculaire :581.71Cas9-IN-1
Cas9-IN-1 is a potent inhibitor of Cas9 with an IC50 value of 7.02 μM. Cas9-IN-1 acts by binding apo-Cas9 and blocking the formation of the Cas9:gRNA complex.Formule :C17H11Cl2F3N2O3SCouleur et forme :SolidMasse moléculaire :451.25FXIa-IN-8
FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.Couleur et forme :SolidHIV-1 protease-IN-6
HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.Formule :C27H31FN2O6SCouleur et forme :SolidMasse moléculaire :530.61Topoisomerase I inhibitor 8
CAS :<p>Topoisomerase I inhibitor 8, a hexacyclic analogue of camptothecin, is also a potent inhibitor of topoisomerase I and is toxic to tumour cells.</p>Formule :C24H21FN2O4Couleur et forme :SolidMasse moléculaire :420.43VVD-118313
CAS :VVD-118313 (5a) is a potent JAK1 inhibitor targeting allosteric cysteine, blocking cytokine signaling for cancer research.Formule :C19H22Cl2N2O3SCouleur et forme :SolidMasse moléculaire :429.364-Bromo A23187
CAS :4-Bromo A23187 is a halogenated analog of the calcium ionophore A-23187. 4-Bromo A23187 is a calcium modulator and induces apoptosis in different cells.Formule :C29H36BrN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :602.52NLRP3-IN-4
NLRP3-IN-4 is an effective, oral NLRP3 inflammasome inhibitor with potent anti-inflammatory effects on colitis.Formule :C22H22N2O5Couleur et forme :SolidMasse moléculaire :394.42CI-1029
CAS :CI-1029: HIV protease inhibitor, combats mutant strains, high efficacy, good bioavailability in animals.Formule :C28H37NO4SCouleur et forme :SolidMasse moléculaire :483.66GSK789
CAS :<p>GSK789 is a selective inhibitor of the first bromodomains (BD1) of the bromo and extra terminal domain (BET) proteins.</p>Formule :C26H33N5O3Couleur et forme :SolidMasse moléculaire :463.57Freselestat quarterhydrate
ONO-6818 quarterhydrate: oral neutrophil elastase inhibitor, Ki 12.2 nM; >100x less effective on other proteases; strong anti-inflammatory.Formule :C23H30N6O5Couleur et forme :SolidMasse moléculaire :457.03CB2 receptor antagonist 1
CAS :Compound 29 is a potent, CB2-selective antagonist/reverse agonist. Derivatives 23 & 24 offer antinociception; 24 activates cannabinoid/TRPV1 receptors.Formule :C28H47NO3Couleur et forme :SolidMasse moléculaire :445.68Acetylpepstatin
CAS :<p>Acetylpepstatin is an inhibitor of HIV-1 protease, HIV-2 protease, aspartyl protease.</p>Formule :C33H61N5O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :703.875CRS-3123
CAS :CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections.Formule :C19H19Br2N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.25Tubulin inhibitor 19
Tubulin inhibitor 19 (9b), a potent indole chalcone, strongly blocks tubulin, valuable in cancer studies.Formule :C21H23NO5Couleur et forme :SolidMasse moléculaire :369.41RmlA-IN-2
RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).Formule :C22H26BrN5O4SCouleur et forme :SolidMasse moléculaire :536.44RXR antagonist 2
RXR antagonist 2 is a potent antagonist of RXR (Ki: 0.391 μM, Kd: 0.281 μM). RXR antagonist 2 has shown research potential for RXR-related diseases.Formule :C29H35F3N2O3Couleur et forme :SolidMasse moléculaire :516.6Enantiomer of Sofosbuvir
Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.Formule :C22H29FN3O9PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.45S1PR1 agonist 2
CAS :S1PR1 agonist 2 is potent for autoimmune research (from WO2021175225A1).Formule :C25H25N5O4Couleur et forme :SolidMasse moléculaire :459.50Xylarianaphthol-1
CAS :<p>Xylarianaphthol-1 is an activator of p21 promoter in a p53-independent manner.</p>Formule :C16H20BrFN2O2Couleur et forme :SolidMasse moléculaire :371.24CHK1 inhibitor
CAS :CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.Formule :C17H21BrN4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.28Salvinorin A Propionate
CAS :Salvinorin A propionate: partial KOR agonist, Ki=32.6 nM, EC50=4.7 nM; ignores μ/δ/ORL-1, non-opioid receptors; less potent analgesic vs. salvinorin A.Formule :C24H30O8Couleur et forme :SolidMasse moléculaire :446.49FGFR-IN-6
CAS :<p>FGFR-IN-6 (Compound 5) is an FGFR inhibitor.</p>Formule :C23H22N6O3Couleur et forme :SolidMasse moléculaire :430.46NLRP3-IN-8
CAS :NLRP3-IN-8, orally active inflammasome blocker, IC50 of 1.23μM, stable (t1/2 = 138.63min), non-toxic (IC50 >100μM).Formule :C23H20N2O6Couleur et forme :SolidMasse moléculaire :420.41rel-SB-612111 hydrochloride
CAS :<p>NOP receptor antagonist</p>Formule :C24H30Cl3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.86TDI-11861
CAS :TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.Formule :C22H25ClF2N6O3Couleur et forme :SolidMasse moléculaire :494.92HIV-1 inhibitor-17
HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).Formule :C32H32N4O5SCouleur et forme :SolidMasse moléculaire :584.69TRK-IN-12
CAS :TRK-IN-12 (9e), a macrocyclic TRK inhibitor (G595R IC50=13.1 nM), outperforms LOXO-101 in Ba/F3-NTRK1 cells.Formule :C18H19ClFN5O3SCouleur et forme :SolidMasse moléculaire :439.89PF-5177624
CAS :PF-5177624 is a selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells.Formule :C25H25FN8O2Couleur et forme :SolidMasse moléculaire :488.52HCV-IN-40
CAS :<p>HCV-IN-39 is a potent oral drug inhibiting HCV, effective on GT1a (EC50: 0.259μM), GT1b (EC50: 0.434μM), GT1b CES1 (EC50: 0.069μM) replicons.</p>Formule :C21H26BrFN3O9PCouleur et forme :SolidMasse moléculaire :594.32CDK2-IN-9
<p>CDK2-IN-9: potent CDK2 inhibitor (IC50: 0.63 μM), anti-proliferative, arrests S/G2M cell cycle, induces apoptosis, promising for melanoma study.</p>Formule :C21H16ClN3O4SCouleur et forme :SolidMasse moléculaire :441.89HDAC-IN-35
HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.Formule :C17H13ClF3N3O3Couleur et forme :SolidMasse moléculaire :399.75DS01080522
DS01080522: PRKACA inhibitor, IC50: kinase 0.8 nM, CREB 66 nM; potential for cancer research.Formule :C23H20Cl2N4O3Couleur et forme :SolidMasse moléculaire :471.34Ambuic acid
CAS :Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.Formule :C19H26O6Couleur et forme :SolidMasse moléculaire :350.41Antibacterial agent 63
CAS :<p>Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to a</p>Formule :C35H43N9O14S2Couleur et forme :SolidMasse moléculaire :877.9Piceid 6″-O-azelaic acid ester
Piceid 6″-O-azelaic acid ester exhibited strong intracellular tyrosinase inhibition and decolorization activity.Formule :C24H36O10Couleur et forme :SolidMasse moléculaire :484.54GLS1 Inhibitor-6
GLS1 Inhibitor-6: IC50=68nM, 220x more selective for GLS2, has anti-tumor and pro-apoptosis effects.Formule :C37H52N6O3SCouleur et forme :SolidMasse moléculaire :660.91GSK-1264
CAS :<p>GSK-1264: allosteric HIV integrase inhibitor, halts viral replication & abnormal protein multimerization.</p>Formule :C26H28FNO5Couleur et forme :SolidMasse moléculaire :453.5Cilobamine mesylate
CAS :Cilobamine mesylate is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects.Formule :C18H27Cl2NO4SCouleur et forme :SolidMasse moléculaire :424.38Calphostin B
CAS :Calphostins, PKC inhibitors from Cladosporium fungus, include A, B, C, D, I; C is most potent.Formule :C37H34O11Couleur et forme :SolidMasse moléculaire :654.66CXCR7 antagonist-1 hydrochloride
CAS :CXCR7 antagonist-1 hydrochloride blocks SDF-1 and I-TAC from CXCR7; may prevent cancer and inflammation.Formule :C21H20ClFN6OCouleur et forme :SolidMasse moléculaire :426.87Mf 268
CAS :<p>Mf 268 is a pseudo-reversible carbamate-type inhibitor which interacts with the catalytic and regulatory anionic site of the enzyme.</p>Formule :C28H46N4O3Couleur et forme :SolidMasse moléculaire :486.69Bafilomycin C1
CAS :vacuolar H+-ATPases (V-ATPases) inhibitorFormule :C39H60O12Degré de pureté :98%Couleur et forme :Light Tan SolidMasse moléculaire :720.89CXCR2 antagonist 5
<p>CXCR2 antagonist 5 (compound 25) binds strongly (IC50=0.013μM) and mobilizes calcium (IC50=0.1μM).</p>Formule :C15H14F2N4O2SCouleur et forme :SolidMasse moléculaire :352.36Npc 12626
CAS :Npc 12626 is a N-methyl-D-aspartate receptor antagonist; NPC 17742, the (2R,4R,5S)-isomer, is the most potent isomer in the mixture NPC 12626.Formule :C11H22NO5PCouleur et forme :SolidMasse moléculaire :279.27TLR7/8 antagonist 1
Compound 16c, an imidazoquinoline, is a TLR7/8 agonist; IC50: 3.91 μM (TLR7), 2.19 μM (TLR8); targets TLR-2050 for disease treatment.Formule :C24H27N5O2Couleur et forme :SolidMasse moléculaire :417.5Antitumor agent-58
<p>Antitumor agent-58 suppresses tumor growth, colony formation, cell migration, and induces mitochondrial dysfunction in MGC-803 cells.</p>Formule :C27H28F3N9SCouleur et forme :SolidMasse moléculaire :567.63MCB-3681
CAS :MCB-3681, active against gram-positive bacterium, is the antibacterial Oxaquin's active substance.Formule :C31H32F2N4O8Couleur et forme :SolidMasse moléculaire :626.6Glutaminyl cyclases-IN-1
<p>Glutaminyl cyclase inhibitor IsoQC-IN-1: IC50=12 nM for QC, 73 nM for isoQC; blocks CD47/SIRPα; boosts THP-1, U937 macrophage phagocytosis.</p>Formule :C25H30N6O2SCouleur et forme :SolidMasse moléculaire :478.61Tubulin polymerization-IN-6
Compound 5f, a potent tubulin polymerization inhibitor (IC50 = 1.09 μM), blocks cell migration, tube formation, and has anti-angiogenic effects.Formule :C19H21NO7Couleur et forme :SolidMasse moléculaire :375.37BW-10
CAS :<p>BW-10 potently inhibits bombesin evoked release of gastrointestinal hormones in vitro and in vivo.</p>Formule :C57H72N14O8Couleur et forme :SolidMasse moléculaire :1081.27GW311616
CAS :GW-311616 is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).Formule :C19H31N3O4SCouleur et forme :SolidMasse moléculaire :397.53CD73-IN-13
CD73-IN-13, a potent CD73 inhibitor, may be developed for tumor-related disease treatment.Formule :C13H11F3N4O2Couleur et forme :SolidMasse moléculaire :312.25Antifungal agent 42
Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.Formule :C22H20Cl2N4Se2Couleur et forme :SolidMasse moléculaire :569.25microRNA-21-IN-1
CAS :<p>microRNA-21-IN-1: microRNA inhibitor, curbs HeLa/HCT-116 growth (IC50: 5.5/2.8 μM), induces HeLa apoptosis, elevates PTEN/EGR1/SLIT2, for cancer research.</p>Formule :C30H37FN6O3Couleur et forme :SolidMasse moléculaire :548.65SCP1-IN-2
<p>SCP1-IN-2: potent, selective SCP1 inhibitor; induces REST degradation, hinders its activity, may study REST-driven glioblastoma growth.</p>Formule :C19H17F3N2O6S2Couleur et forme :SolidMasse moléculaire :490.47MRK003
CAS :MRK003, a γ-secretase inhibitor, induces apoptosis, halts cell growth in myeloma/NHL, and affects notch signaling and PI3K/Akt pathway.Formule :C25H31F6N3O2SCouleur et forme :SolidMasse moléculaire :551.59
