Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.542 produits)
- Apoptose(5.816 produits)
- Cycle cellulaire/point de contrôle(4.466 produits)
- Chromatine/Épigénétique(2.252 produits)
- Signalisation du cytosquelette(1.381 produits)
- Altération de l'ADN/réparation de l'ADN(2.830 produits)
- Endocrinologie/Hormones(3.518 produits)
- Enzyme(3.640 produits)
- GPCR/G-Protéine(8.362 produits)
- Immunologie et Inflammation(3.540 produits)
- Virus de la grippe(296 produits)
- Signalisation JAK/STAT(405 produits)
- Signalisation MAPK(1.201 produits)
- Transporteur membranaire/Canal ionique(2.809 produits)
- Métabolisme(9.462 produits)
- Microbiologie/Virologie(7.003 produits)
- Neuroscience(9.942 produits)
- Autres inhibiteurs(37.827 produits)
- Oxydation-Réduction(40 produits)
- Signalisation PI3K/Akt/mTOR(1.399 produits)
- Protéases/Protéasome(1.598 produits)
- Cellules souche et Dérivés(830 produits)
- Tyrosine Kinase/Adaptateurs(2.012 produits)
- Ubiquitination(1.651 produits)
Affichez 16 plus de sous-catégories
66618 produits trouvés pour "Inhibiteurs"
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KRAS G12D inhibitor 16
CAS :<p>KRAS G12D inhibitor 16 targets KRAS G12D with IC50 of 0.7 nM and mutant form at 0.35 μM, useful in various cancer studies.</p>Formule :C32H39IN6O3Couleur et forme :SolidMasse moléculaire :682.59PI3K-IN-29
CAS :<p>PI3K-IN-29: Strong PI3K block, inhibits Akt phosphorylation. IC50: U87MG 0.264µM, HeLa 2.04µM, HL60 1.14µM.</p>Formule :C27H22ClN7O3SCouleur et forme :SolidMasse moléculaire :560.03Antibacterial agent 82
<p>Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].</p>Formule :C22H18N2O2Couleur et forme :SolidMasse moléculaire :342.39CH-38083
CAS :<p>CH-38083 is a selective and effective alpha-2 adrenoceptors antagonist.</p>Formule :C18H24ClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :337.84Bafilomycin C1
CAS :<p>vacuolar H+-ATPases (V-ATPases) inhibitor</p>Formule :C39H60O12Degré de pureté :98%Couleur et forme :Light Tan SolidMasse moléculaire :720.89SOS1-IN-9
<p>SOS1-IN-9 is a potent inhibitor of SOS1 that acts on KRAS G12C-SOS1 (IC50: 116.5 nM).</p>Formule :C22H28F3N5OCouleur et forme :SolidMasse moléculaire :435.49LSD1-IN-21
<p>LSD1-IN-21: potent LSD1 inhibitor, crosses blood-brain barrier, IC50 of 0.956 μM; lowers TNF-α, anti-cancer, anti-inflammatory.</p>Formule :C24H25N5O2SCouleur et forme :SolidMasse moléculaire :447.55Holothurinogenin
CAS :<p>Holothurinogenin, as a lanosterol derivative, has toxic to nerve tissue.</p>Formule :C30H46O4Couleur et forme :SolidMasse moléculaire :470.68SLC4011540
<p>SLC4011540 is a potent and selective SphK1/2 dual inhibitor with Ki value of 120 nM and 90 nM respectively.</p>Formule :C24H23ClF3N7OSCouleur et forme :SolidMasse moléculaire :550PAIR2
CAS :<p>PAIR2 is a selective IRE1α RNase partial antagonist, blocking its ATP site and preventing KIRA from hindering XBP1 splicing.</p>Formule :C27H26F4N6O3SCouleur et forme :SolidMasse moléculaire :590.59NNC 55-0396
CAS :<p>NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.</p>Formule :C30H40Cl2FN3O2Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :564.56U 80215
CAS :<p>U 80215 is an enzyme-competitive inhibitor.</p>Formule :C42H60N8O6SCouleur et forme :SolidMasse moléculaire :805.04Valbenazine tosylate
CAS :<p>Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no</p>Formule :C38H54N2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :762.97OP-5244
CAS :<p>OP-5244 has comparable potency to bisphosphonic acid series and targets CD73.</p>Formule :C19H29ClN5O9PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :537.8915-keto-Prostaglandin E2
CAS :<p>15-keto-Prostaglandin E2, an endogenous metabolite, inhibits STAT3 activation through binding to Cys259 and regulates breast cancer cell growth and progression.</p>Formule :C20H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.45RWJ-56110
CAS :<p>protease-activated receptor-1 (PAR1) antagonist</p>Formule :C41H43Cl2F2N7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :790.73OICR-9429-N-C2-NH2
CAS :<p>OICR-9429-N-C2-NH2, a ligand for WDR5, intermediate 2, serves as a crucial compound in the synthesis of PROTACs.</p>Formule :C31H38F3N7O2Couleur et forme :SolidMasse moléculaire :597.687RS 12254
CAS :<p>RS 12254 is a dopamine agonist and antihypertensive agent.</p>Formule :C28H40N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.63LRRK2-IN-3
CAS :<p>LRRK2-IN-3: potent, selective oral LRRK2 blocker, BBB-penetrant, IC50 of 0.6 nM in hPBMCs, for Parkinson's research.</p>Formule :C25H29ClF2N6O2Couleur et forme :SolidMasse moléculaire :518.99PS-519
CAS :<p>PS-519 is a human tissue plasminogen activator and proteasome inhibitor.</p>Formule :C12H19NO4Couleur et forme :SolidMasse moléculaire :241.28Aplaviroc
CAS :<p>Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.</p>Formule :C33H43N3O6Degré de pureté :97.98% - 98.26%Couleur et forme :SolidMasse moléculaire :577.71G-744
CAS :<p>G-744 is a selective and orally active inhibitor of Btk (IC50: 2 nM).</p>Formule :C29H29N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.64Hoe 892
CAS :<p>Hoe 892 is a stable thia-thimo-analogue of prostacyclin and acts as a platelet aggregation inhibitor.</p>Formule :C20H33NO4SCouleur et forme :SolidMasse moléculaire :383.55NTPDase-IN-2
CAS :<p>NTPDase-IN-2 inhibits h-NTPDase-2/-8 (IC50: 0.04, 2.27 µM), non-competitive for h-NTPDase-1/-2 (Km: 74 µM); useful in cancer, immune, bacterial research.</p>Formule :C24H20FN3OS2Couleur et forme :SolidMasse moléculaire :449.56trans-Doxercalciferol
CAS :<p>trans-Doxercalciferol is an isomer of Doxercalciferol. Doxercalciferol is an activator of the Vitamin D receptor and prevents renal disease.</p>Formule :C28H44O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.65Isoleucyl tRNA synthetase-IN-2
CAS :<p>Isoleucyl tRNA synthetase-IN-2 is a selective and potent inhibitor (Ki: 114 nM) that targets isoleucyl tRNA synthetase (IleRS).</p>Formule :C22H33N5O8SCouleur et forme :SolidMasse moléculaire :527.59NSC381467
CAS :<p>NSC381467: Potent, oral EGFR-TK inhibitor with strong antiproliferative effects, promising for cancer research.</p>Formule :C20H16O7Couleur et forme :SolidMasse moléculaire :368.34Diguanosine 5′-triphosphate lithium
<p>Diguanosine 5′-triphosphate (Gp3G) lithium is a dinucleoside triphosphate and a virus-specific oligonucleotide.Diguanosine 5′-triphosphate lithium is required</p>Formule :C20H27N10O18P3·xLiCouleur et forme :Solid(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formule :C14H10ClN3S2Couleur et forme :SolidMasse moléculaire :319.83Azonafide-PEABA
CAS :<p>Azonafide-PEABA is a drug moiety with cytotoxic [1].</p>Formule :C32H33N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :551.64Taprostene
CAS :<p>Taprostene (CG-4203), a stable Prostacyclin analogue, protects endothelium and myocardium post-ischemia in cats, with minimal hemodynamic impact.</p>Formule :C24H30O5Couleur et forme :SolidMasse moléculaire :398.49DIDS
CAS :<p>DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.</p>Formule :C16H10N2O6S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.52BF-168
CAS :<p>BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).</p>Formule :C18H17FN2O2Couleur et forme :SolidMasse moléculaire :312.34A1AR antagonist 1
<p>Compound 18g, a potent A1AR blocker with Ki: 2.08 nM (hA1), 6.91 nM (hA2A), 31.2 nM (hA2B).</p>Formule :C18H14N4OCouleur et forme :SolidMasse moléculaire :302.33α-Glucosidase-IN-18
<p>α-Glucosidase-IN-18 (7B) is an orally active inhibitor of α-glucosidase, displaying an IC 50 value of 3.96 μM.</p>Formule :C23H19NO2SCouleur et forme :SolidMasse moléculaire :373.47ZLM-66
<p>ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.</p>Couleur et forme :SolidBI-207524
CAS :<p>BI-207524 is a novel NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection.</p>Formule :C35H36ClN5O5Couleur et forme :SolidMasse moléculaire :642.14LY2934747
CAS :<p>LY2934747 is a novel, potent, and systemically bioavailable mGlu2/3 receptor agonist, exhibiting both antipsychotic and analgesic properties in vivo.</p>Formule :C10H13NO4Couleur et forme :SolidMasse moléculaire :211.21HER2-IN-11
<p>HER2-IN-11 is a psoralen derivative that induces apoptosis. HER2-IN-11 shows light-activated cytotoxicity and also exhibits anti-breast cancer activity [1].</p>Formule :C17H11NO6Couleur et forme :SolidMasse moléculaire :325.27Anticancer agent 26
<p>Anticancer agent 26 is a promising candidate for cancer therapy and deserves further development.</p>Formule :C28H33NO5Couleur et forme :SolidMasse moléculaire :463.57ND-654
CAS :<p>ND-654 is an acetyl CoA carboxylase inhibitor.</p>Formule :C29H33N3O8SCouleur et forme :SolidMasse moléculaire :583.65GNE-886
CAS :<p>GNE-886 has a wide range of applications in life science related research.</p>Formule :C28H30N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.59Indinavir monohydrate
CAS :<p>Indinavir monohydrate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.</p>Formule :C36H49N5O5Couleur et forme :SolidMasse moléculaire :631.82NLRP3/AIM2-IN-1
<p>NLRP3/AIM2-IN-1 is an inhibitor of thermal sepsis (IC50 = 3.136 ± 0.7667 μM).</p>Formule :C15H16BNO4Couleur et forme :SolidMasse moléculaire :285.1Atorvastatin 3-Deoxyhept-2E-Enoic Acid
CAS :Atorvastatin 3-Deoxyhept-2E-Enoic Acid, an impurity in Atorvastatin, lowers blood lipids as an HMG-CoA reductase inhibitor.Formule :C33H33FN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.62Ganciclovir monophosphonate
CAS :<p>Ganciclovir monophosphate treats CMV, inhibiting replication in human/animal strains (IC50: 0.01μM).</p>Formule :C10H16N5O6PCouleur et forme :SolidMasse moléculaire :333.24IRAK4-IN-19
<p>IRAK4-IN-19, an IRAK4 inhibitor (IC50: 4.3 nM), hampers IL23 synthesis and arthritis progression.</p>Formule :C25H26F2N8OCouleur et forme :SolidMasse moléculaire :492.52A4B17
<p>A4B17 is an inhibitor of androgen receptor N-terminal with potential for androgen-responsive prostate cancer treatment.</p>Formule :C14H7F4NSCouleur et forme :SolidMasse moléculaire :297.27Ribocil-C R enantiomer
<p>Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor.</p>Formule :C21H21N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.5WDR5-IN-5
CAS :<p>WDR5-IN-5: Selective oral inhibitor for WDR5's WIN site with high affinity (Ki<0.02 nM) and anti-cancer properties. Good pharmacokinetics.</p>Formule :C29H29F3N6OCouleur et forme :SolidMasse moléculaire :534.58JAK3-IN-7
CAS :<p>JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction after</p>Formule :C17H20N6ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :324.38YCW-E11
CAS :<p>YCW-E11 is an antiapoptotic Bcl-2 family proteins inhibitor.</p>Formule :C25H21Cl2N3O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.49IACS-8779
CAS :<p>IACS-8779 is a potent STING agonist that efficiently stimulates interferon gene activity and exhibits strong systemic antitumor effects.</p>Formule :C21H25N9O10P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :689.55FLT3-IN-13
<p>FLT3-IN-13 inhibits topoisomerase II/FLT3 in leukemia with IC50 of 2.26 μM, causes G2/M arrest, and promotes apoptosis.</p>Formule :C20H14N4O2Couleur et forme :SolidMasse moléculaire :342.35AD5075
CAS :<p>AD5075 is a bioactive chemical.</p>Formule :C22H20N2O5SCouleur et forme :SolidMasse moléculaire :424.47EGFR-IN-45
<p>EGFR-IN-45: Strong EGFR/CDK2 inhibitor (IC50s: 0.4 & 1.6 μM), halts cancer cell cycle pre-G1, prompts apoptosis, also targets Topo I/II.</p>Formule :C28H23N7OCouleur et forme :SolidMasse moléculaire :473.53FGI-106
CAS :<p>FGI-106 combats Ebola, Rift Valley, Dengue Fever, HCV, and HIV-1; EC50s range from 100-900 nM.</p>Formule :C28H38N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.64ICA-105665
CAS :ICA-105665 is an orally active Kv7.2/7.3/7.5 channel opener, CNS-penetrant with antiseizure effects, and low hepatocyte cytotoxicity.Formule :C19H15F2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.34Stauprimide
CAS :<p>Stauprimide inhibits MYC by blocking NME2, reducing MYC transcription in ESCs.</p>Formule :C35H28N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :584.62Adecypenol
CAS :<p>Adecypenol is a unique adenosine deaminase inhibitor. It shows effective inhibitory activity against calf intestinal adenosine deaminase.</p>Formule :C12H16N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :280.28SJG-136
CAS :SJG-136 is a DNA cross-linking agent (XL50: 45 nM for pBR322 DNA).Formule :C31H32N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.61ALK-IN-23
<p>ALK-IN-23 inhibits ALK (IC50: 1.6-0.71 nM), hinders cancer cell spread, forms colonies in vitro, and reduces tumors in mice with low toxicity.</p>Formule :C26H29ClN8O3SCouleur et forme :SolidMasse moléculaire :569.08Antitubercular agent-15
<p>Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.</p>Formule :C21H29FN2Couleur et forme :SolidMasse moléculaire :328.47CLK1/4-IN-1
<p>CLK1/4-IN-1 inhibits Clk1/4 (IC50: 9.7/6.6 nM), curbing T24 cell growth (GI50: 1.1 μM). Potential cancer research tool.</p>Formule :C18H14ClNO4SCouleur et forme :SolidMasse moléculaire :375.83FTI-2148
CAS :<p>FTI-2148 blocks RAS-related FT-1 & GGT-1; IC50: 1.4 nM & 1.7 μM.</p>Formule :C24H28N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.57DC41
CAS :<p>DC41 is a CC-1065-based cancer drug, an antibody-linked DNA alkylator.</p>Formule :C37H34ClN5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :680.22FTO-IN-4
CAS :<p>FTO-IN-4 is a potent and selective inhibitor of adiposity and obesity-associated protein (FTO).</p>Formule :C22H16Cl2N6O6Couleur et forme :SolidMasse moléculaire :531.31PD 135158
CAS :PD 135158 is a CCK2 receptor antagonist.Formule :C42H61N5O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :811.96NPR-C activator 1
CAS :<p>NPR-C activator 1 is an activator of the natriuretic peptide receptor C (NPR-C), which can be used to study cardiovascular diseases.</p>Formule :C18H24N6O3Degré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :372.42Detajmium
CAS :Detajmium is an anti-arrhythmia compound. It is an Na(+)-channel-blocking drug with an extremely long recovery from use-dependent sodium channel block.Formule :C27H42N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :456.64AZD 2066 hydrate
<p>AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].</p>Formule :C19H18ClN5O3Couleur et forme :SolidMasse moléculaire :386.33Antibiotic LL Z1640-2
CAS :<p>Antibiotic LL Z1640-2 is an inhibitor against the TAK1 activity.</p>Formule :C19H22O7Couleur et forme :SolidMasse moléculaire :362.38BRD2879
CAS :<p>BRD2879 is a potent and cell-active inhibitor of IDH1-R132H (IC50 = 50 nM).</p>Formule :C30H38FN3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :571.70WEHI-9625
CAS :<p>WEHI-9625 is a tricyclic sulfone small molecule apoptosis inhibitor (EC50: 69 nM).</p>Formule :C34H27NO5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.71COX-2-IN-7
<p>COX-2-IN-7: potent, orally active COX-2 inhibitor with higher selectivity than Celecoxib, IC50 6.585 uM, anti-inflammatory, low ulcer risk.</p>Formule :C15H13N3O2S2Couleur et forme :SolidMasse moléculaire :331.41J-104132
CAS :<p>J-104132: potent human ETA/B antagonist; Ki: ETA=0.034nM, ETB=0.104nM; prevents ET-1 effects, ED50 i.v.=0.045mg/kg, p.o.=0.35mg/kg.</p>Formule :C31H33NO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.60VVD-118313
CAS :<p>VVD-118313 (5a) is a potent JAK1 inhibitor targeting allosteric cysteine, blocking cytokine signaling for cancer research.</p>Formule :C19H22Cl2N2O3SCouleur et forme :SolidMasse moléculaire :429.36Anti-inflammatory agent 6
<p>Anti-inflammatory agent 6 blocks IKKα/β, IκBα, and NF-κB p65 phosphorylation, key to controlling inflammation.</p>Formule :C22H20O12Couleur et forme :SolidMasse moléculaire :476.39Freselestat quarterhydrate
<p>ONO-6818 quarterhydrate: oral neutrophil elastase inhibitor, Ki 12.2 nM; >100x less effective on other proteases; strong anti-inflammatory.</p>Formule :C23H30N6O5Couleur et forme :SolidMasse moléculaire :457.03FLT3/TrKA-IN-1
<p>FLT3/TrKA-IN-1: Potent dual kinase inhibitor for FLT3 & TrKA, promising for AML research.</p>Formule :C28H30N4O2Couleur et forme :SolidMasse moléculaire :454.56PRMT5-IN-1 hydrochloride
<p>PRMT5 IN-1 hydrochloride is a potent PRMT5 inhibitor (IC50: 11 nM), forms covalent adduct with C449, and converts to an aldehyde in vivo.</p>Formule :C19H20Cl2N4O5Couleur et forme :SolidMasse moléculaire :455.29Pulvomycin
CAS :<p>Pulvomycin is a protein biosynthesis inhibitor preventing ternary complex formation between elongation factor Tu, GTP, and aminoacyl-tRNA.</p>Formule :C47H66O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :839.032BMS-986339
CAS :<p>BMS-986339: oral, potent FXR agonist; binds to His298/ASN287; for PBC, PSC, NASH, anti-fibrosis research.</p>Formule :C35H41F4N3O4Couleur et forme :SolidMasse moléculaire :643.71Tubulin inhibitor 19
<p>Tubulin inhibitor 19 (9b), a potent indole chalcone, strongly blocks tubulin, valuable in cancer studies.</p>Formule :C21H23NO5Couleur et forme :SolidMasse moléculaire :369.41Esorubicin
CAS :<p>Esorubicin, a doxorubicin derivative, intercalates DNA, inhibits topoisomerase II, has less cardiotoxicity, but more myelosuppression.</p>Formule :C27H29NO10Couleur et forme :SolidMasse moléculaire :527.52RXR antagonist 2
<p>RXR antagonist 2 is a potent antagonist of RXR (Ki: 0.391 μM, Kd: 0.281 μM). RXR antagonist 2 has shown research potential for RXR-related diseases.</p>Formule :C29H35F3N2O3Couleur et forme :SolidMasse moléculaire :516.6CXCR7 modulator 2
CAS :CXCR7 modulator 2 is a 7-type C-X-C chemokine receptor (CXCR7) modulator with a Ki of 13 nM.Formule :C29H42N6O3Couleur et forme :SolidMasse moléculaire :522.68DNDI-8219
CAS :<p>DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.</p>Formule :C13H10F3N3O5Couleur et forme :SolidMasse moléculaire :345.23FT001
CAS :<p>FT001: Oral BET Bromodomain inhibitor, IC50=0.46μM, suppresses MYC, anti-cancer, effective in vitro/vivo.</p>Formule :C25H29N3O4SDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :467.58O-Desmethyl Midostaurin
CAS :O-Desmethyl Midostaurin is the active Midostaurin metabolite via cytochrome P450 liver enzyme metabolism.Formule :C34H28N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.61DBCO-Sulfo-Link-biotin
CAS :DBCO-Sulfo-Link-biotin is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].Formule :C31H35N5O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :653.77Kahweol linoleate
CAS :<p>Kahweol linoleate, a semi-synthetic from coffee, blocks osteoclast creation, fights cancerous cells, prevents DNA damage, and reduces oxidative stress.</p>Formule :C38H56O4Couleur et forme :SolidMasse moléculaire :576.85hCAII-IN-5
CAS :<p>hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].</p>Formule :C29H18N2O7Couleur et forme :SolidMasse moléculaire :506.46GLS1 Inhibitor-6
<p>GLS1 Inhibitor-6: IC50=68nM, 220x more selective for GLS2, has anti-tumor and pro-apoptosis effects.</p>Formule :C37H52N6O3SCouleur et forme :SolidMasse moléculaire :660.91RS 61756-007
CAS :<p>RS 61756-007 is a selective thromboxane receptor (TP) agonist.</p>Formule :C23H28O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.47GP-1681
CAS :<p>GP-1681, a G-protein coupled receptor (GPCR) agonist, is used potentially for the treatment of influenza infection.</p>Formule :C24H30NaO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.48LY 235959
CAS :<p>LY 235959 is a NMDA receptor antagonist.</p>Formule :C11H20NO5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :277.25SphK2-IN-2
<p>SphK2-IN-2 (21g) is a potent and selective inhibitor of SphK2 (IC50: 0.23 μM).</p>Formule :C21H25ClN10OCouleur et forme :SolidMasse moléculaire :468.94Anticancer agent 54
<p>Anticancer agent 54 blocks cell cycle in G0/G1, induces apoptosis, and fights cancer via DNA embedding and ROS.</p>Formule :C33H36N6Couleur et forme :SolidMasse moléculaire :516.68Revamilast
CAS :<p>Revamilast, also known as GRC4039, is a phosphodiesterase IV inhibitor for potentially treating of asthma and rheumatoid arthritis</p>Formule :C18H9Cl2F2N3O4Couleur et forme :SolidMasse moléculaire :440.18DNA crosslinker 2 dihydrochloride
CAS :<p>Potent DNA crosslinker 2 binds minor groove, increases Tm by 1.2°C, and inhibits NCI-H460, A2780, MCF-7 cancer cells.</p>Formule :C15H22Cl2N8OCouleur et forme :SolidMasse moléculaire :401.29HSP90-IN-10
<p>HSP90-IN-10 is a potent HSP90 inhibitor, targeting HCC1954 cells (IC50: 6 μM) and inducing apoptosis, sparing normal cells.</p>Formule :C30H26FN3O6Couleur et forme :SolidMasse moléculaire :543.54Tubulin inhibitor 13
CAS :<p>Tubulin inhibitor 13 (E27), IC50 16.1 μM, blocks tubulin polymerization, cancer cell migration, and invasion, induces apoptosis.</p>Formule :C25H21N3O4Couleur et forme :SolidMasse moléculaire :427.45L-I-OddU
CAS :<p>L-I-OddU: Selective anti-EBV, halts virus DNA/protein synthesis. EC50: 0.03 µM, low toxicity (CC50: 1000 nM).</p>Formule :C8H9IN2O5Couleur et forme :SolidMasse moléculaire :340.07GSK3527497 HCl
CAS :<p>GSK3527497: potent TRPV4 inhibitor, IC50=12 nM, targets heart/respiratory issues, for oral/IV use, low-dose effective.</p>Formule :C17H17Cl2FN4O4SCouleur et forme :SolidMasse moléculaire :463.3054DI-404
CAS :<p>DI-404: Potent DCN1-UBC12 inhibitor, selectivity blocks cullin 3 neddylation, Kd=6.9 nM.</p>Formule :C35H45ClN6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :713.29MIV-150
CAS :MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).Formule :C19H17FN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.36Aniline-MPB-amino-C3-PBD
CAS :<p>Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised of the non-alkylating group. It is a sequence-selective DNA minor-groove binding agent.</p>Formule :C42H46N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :758.86SARS-CoV-2-IN-22
CAS :<p>SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus inhibitor (IC50: 16.96 μM).</p>Formule :C27H24N2O3SCouleur et forme :SolidMasse moléculaire :456.56Aβ42-IN-1
CAS :<p>Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).</p>Formule :C29H27ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :499Aurora inhibitor 1
CAS :<p>Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).</p>Formule :C23H25N9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.57α-Glucosidase-IN-15
<p>α-Glucosidase-IN-15 (Compound 14B) exhibits potent inhibitory activity against α-glucosidase, with an IC50 value of 3.34 μM.</p>Formule :C24H24N2SCouleur et forme :SolidMasse moléculaire :372.53Leualacin
CAS :<p>Leualacin is a novel calcium blocker from Hapsidospora irregularis.</p>Formule :C31H47N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.72Zurletrectinib
CAS :<p>Zurletrectinib is a tyrosine kinase inhibitor with potential as an antineoplastic agent.</p>Formule :C19H19F2N7O2Couleur et forme :SolidMasse moléculaire :415.4Udifitimod
CAS :<p>Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.</p>Formule :C25H33NO2Couleur et forme :SolidMasse moléculaire :379.54KU-32
CAS :<p>KU-32 is a novel and novobiocin-based Hsp90 inhibitor. It can protect against neuronal cell death.</p>Formule :C20H25NO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.41SR121566A
CAS :SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).Formule :C20H25N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.51CEP-14083
CAS :<p>CEP-14083: potent ALK inhibitor, effective in NPM/ALK T-cell lymphoma, binds ATP site; IC50=11 nmol/L, also inhibits insulin receptor, preclinical efficacy.</p>Formule :C31H30N6O2Couleur et forme :SolidMasse moléculaire :518.61Enprostil
CAS :<p>Enprostil: synthetic PGE2 analog, reduces gastric acid, protects mucosa, lowers post-meal gastrin, treats ulcers effectively and safely.</p>Formule :C23H28O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.46LY210073
CAS :<p>LY210073 is an antagonist of the Leukotriene B4 (LTB4) receptor (IC50: 6.2 nM).</p>Formule :C30H28O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :516.54NRX-2663
CAS :<p>NRX-2663 boosts β-catenin binding to E3 ligase SCFβ-TrCP (Kd: 54.8 nM, EC50: 22.9 nM).</p>Formule :C20H13F3N2O5Couleur et forme :SolidMasse moléculaire :418.32MDK-3298
CAS :MDK-3298 is a reversible covalent inhibitor of Mcl-1, a target of protein-protein interaction (PPI).Formule :C35H32BN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :617.46Homodestcardin
CAS :<p>Homodestcardin: cyclic depsipeptide from T. roseum with immunosuppressant properties; inhibits mouse T cell proliferation.</p>Formule :C32H55N5O7Couleur et forme :SolidMasse moléculaire :621.81PRMT5-IN-1
CAS :<p>PRMT5-IN-1 is a covalent inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50 of 11 nM for PRMT5/MEP50).</p>Formule :C19H19ClN4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :418.83MCTR3
CAS :<p>MCTR3, derived from DHA via maresin 1 in macrophages, hastens tissue healing and reduces inflammation and eicosanoids post-E. coli infection in mice.</p>Formule :C25H37NO5SCouleur et forme :SolidMasse moléculaire :463.63EB-0156
<p>EB-0156: potent ER α-glucosidase inhibitor, IC50 of 0.0479/ <0.001 μM, N-substituted valerian, broad-spectrum antiviral potential.</p>Formule :C21H32N6O7Couleur et forme :SolidMasse moléculaire :480.51FAAH/MAGL-IN-2
CAS :<p>FAAH/MAGL-IN-2: potent, reversible, oral FAAH & MAGL inhibitor, IC50: 11/36 nM, may research neuropathic pain, no locomotion issue.</p>Formule :C15H13Cl2N3O3SCouleur et forme :SolidMasse moléculaire :386.25Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Formule :C22H20Cl2N4SeCouleur et forme :SolidMasse moléculaire :490.29EGFR/HER2-IN-4
<p>EGFR/HER2-IN-4: oral, irreversible dual EGFR inhibitor (IC50: 0.6 nM), targets L858R/T790M mutations, potent anti-lung cancer effects in vivo.</p>Couleur et forme :SolidJAK3/BTK-IN-4
CAS :<p>JAK3/BTK-IN-4, a dual inhibitor for JAK3/BTK, shows synergy in autoimmune disease treatment. (Patent WO2021147953A1, compound 003)</p>Formule :C21H25ClN8OCouleur et forme :SolidMasse moléculaire :440.93Ambelline
CAS :<p>Ambelline has antitumor activity.</p>Formule :C18H21NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.36Pomaglumetad methionil
CAS :<p>Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.</p>Formule :C12H20N2O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.43Antitumor agent-48
<p>Antitumor agent-48, a 2,3-dehydrosilybin derivative, exhibits cytotoxicity on MCF-7, NCI-H1299, HepG2, HT29 cells; IC50 ranging 8.06-16.51 µM.</p>Formule :C35H34N2O14Couleur et forme :SolidMasse moléculaire :706.65Purine phosphoribosyltransferase-IN-1
<p>Compound (S,R)-48 inhibits Pf, Pv, & Tbr PRT with Ki of 50, 20, 2 nM.</p>Formule :C11H15N5Na4O10P2Couleur et forme :SolidMasse moléculaire :531.17(Rac)-OSMI-1
<p>(Rac)-OSMI-1, a racemate, inhibits OGT (IC50: 2.7 μM) affecting O-GlcNAcylation without changing surface glycans.</p>Formule :C28H25N3O6S2Couleur et forme :SolidMasse moléculaire :563.64BRD0418
CAS :<p>BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.</p>Formule :C29H32N2O5Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :488.57JNJ-1250132
CAS :<p>JNJ-1250132 is a steroidal progesterone receptor modulator that inhibits binding of the receptor to DNA in vitro.</p>Formule :C33H41NO4Couleur et forme :SolidMasse moléculaire :515.68nNOS-IN-25
CAS :nNOS-IN-25 is an effective, selective, and cell-permeable inhibitor of neuronal nitric oxide synthase.Formule :C21H22N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :330.43Antiallergic agent-1
<p>Antiallergic agent-1, an Src family kinase inhibitor, is a new and valuable lead compound with potential as an anti-allergic agent.</p>Formule :C27H19F6N5OCouleur et forme :SolidMasse moléculaire :543.46Homomoschatoline
CAS :Homomoschatoline is an antibacterial isolated from Artabotrys crassifolius.Formule :C19H15NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :321.33Antibacterial agent 118
<p>Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.</p>Formule :C19H21N5O2SCouleur et forme :SolidMasse moléculaire :383.47FTO-IN-6
CAS :<p>FTO-IN-6 is a selective inhibitor of fat mass and obesity associated protein (FTO).</p>Formule :C14H12N4O6Couleur et forme :SolidMasse moléculaire :332.27HIV-1 inhibitor-44
<p>HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).</p>Formule :C23H26N2O4SCouleur et forme :SolidMasse moléculaire :426.53LP 12 hydrochloride hydrate
<p>LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.</p>Formule :C32H39N3O·HCl·xH2OCouleur et forme :SolidTuvatidine
CAS :<p>Tuvatidine is a histamine 2 receptor antagonist.</p>Formule :C10H17N9O2S3Couleur et forme :SolidMasse moléculaire :391.5GLPG0492 (R enantiomer)
CAS :GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, a novel selective androgen receptor modulator.Formule :C19H14F3N3O3Couleur et forme :SolidMasse moléculaire :389.33ATUX-1215
CAS :<p>ATUX-1215, a protein phosphatase 2A (PP2A) activator, diminishes the phosphorylation of ERK, p38, JNK, and Akt, as well as decreases the secretion of IL-12p70,</p>Formule :C27H24F5NO4SCouleur et forme :SolidMasse moléculaire :553.54Triphen diol
CAS :<p>Triphen diol, a phenol diol, fights pancreatic cancer & cholangiocarcinoma, inducing apoptosis via caspase-dependent & -independent paths.</p>Formule :C22H20O4Couleur et forme :SolidMasse moléculaire :348.39MRS4458
CAS :<p>MRS4458 is an effective inhibitor of the P2Y14 Receptor.</p>Formule :C24H20F3N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :515.515α-reductase-IN-1
CAS :<p>5α-reductase-IN-1 is a potent inhibitor of the enzyme 5α-reductase.</p>Formule :C31H37NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :503.63Dopamine D3 receptor antagonist-1
<p>Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic</p>Formule :C31H35Cl2N3O3Couleur et forme :SolidMasse moléculaire :568.53Epolactaene
CAS :<p>Epolactaene: neuritogenic, inhibits mammalian DNA polymerases & human DNA topoisomerase II.</p>Formule :C21H27NO6Couleur et forme :SolidMasse moléculaire :389.44Iralukast (CGP 45715A)
CAS :<p>Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.</p>Formule :C38H37F3O8SCouleur et forme :SolidMasse moléculaire :710.76AY 17,605
CAS :<p>AY 17,605 is an inhibitor of bovine heart and rat brain nucleoside-3',5'- monophosphate phosphodiesterase.</p>Formule :C25H36O5Couleur et forme :SolidMasse moléculaire :416.55Anticancer agent 68
CAS :<p>Compound 12, an anticancer agent, halts G2/M phase, triggers cell death, and activates p53 & PTEN for tumor suppression.</p>Formule :C20H18ClNO5Couleur et forme :SolidMasse moléculaire :387.81PF-07202954
CAS :<p>PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM against</p>Formule :C22H23FN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.45GSK579289A
CAS :<p>GSK579289A is an inhibitor of benzimidazole thiophene.</p>Formule :C26H27ClN4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.04PD-149163
CAS :<p>PD-149163: brain-penetrating, selective NTR1 agonist; shows pro-cognitive, anti-psychotic, anxiolytic effects.</p>Formule :C42H71N9O6Couleur et forme :SolidMasse moléculaire :798.07DNA-PK-IN-6
CAS :<p>DNA-PK-IN-6 inhibits DNA-PKcs, disrupting tumor DNA repair and triggering apoptosis; enhances radiotherapy and targets various tumors (WO2021197159A1).</p>Formule :C19H21N7OCouleur et forme :SolidMasse moléculaire :363.42ADH-6
CAS :<p>ADH-6, a tripyridylamide, disrupts mutant p53 aggregates in cancer cells, reviving its function and inducing apoptosis.</p>Formule :C29H36N8O9Couleur et forme :SolidMasse moléculaire :640.64TRβ agonist 1
CAS :<p>TRβ Agonist 1, a selective and mutation-sensitive thyroid hormone receptor β (TRβ) agonist, demonstrates an EC50 value of 21 nM.</p>Formule :C29H25FN2O8Couleur et forme :SolidMasse moléculaire :548.52Hesperadin hydrochloride
<p>Hesperadin hydrochloride is an ATP-competitive indolone inhibitor of Aurora A and B, with an IC50 value of 250 nM for Aurora B.</p>Formule :C29H33ClN4O3SCouleur et forme :SolidMasse moléculaire :553.12BTK-IN-15
<p>BTK-IN-15: Oral BTK inhibitor, IC50 0.7 nM, induces cancer cell apoptosis, selective with anti-tumor effects.</p>Formule :C28H24FN5O2Couleur et forme :SolidMasse moléculaire :481.52(±)-ANAP hydrochloride
CAS :<p>'(±)-ANAP hydrochloride, an unnatural amino acid analog of prodan, serves as a fluorescent probe with enhanced environmental sensitivity.'</p>Formule :C15H17ClN2O3Couleur et forme :SolidMasse moléculaire :308.76DMP 728
CAS :<p>DMP 728 is an antagonist of Glycoprotein IIb-IIIa.</p>Formule :C26H40N8O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :656.71Iroxanadine hydrobromide
CAS :Iroxanadine hydrobromide is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.Formule :C14H21BrN4OCouleur et forme :SolidMasse moléculaire :341.25Dinordrin
CAS :Dinordrin is an implantation inhibitor and hormone.Formule :C27H36O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.57Flurandrenolone Acetate
CAS :<p>Flurandrenolone Acetate, a synthetic glucocorticoid derived from Flurandrenolide, is used to study skin issues like eczema and psoriasis.</p>Formule :C26H35FO7Couleur et forme :SolidMasse moléculaire :478.55Tubulin polymerization-IN-4
CAS :<p>Tubulin polymerization-IN-4: inhibits tubulin (IC50=4.6 μM), blocks G2/M phase, induces apoptosis, hinders cell cloning/migration, damages vasculature.</p>Formule :C21H21ClN2O4Couleur et forme :SolidMasse moléculaire :400.86Quinagolide hydrochloride
CAS :Quinagolide hydrochloride is a selective agonist of dopamine D2 receptor.Formule :C20H34ClN3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.02TRPA1 Antagonist 1
CAS :<p>TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate prodrug which converts to its active parent drug.</p>Formule :C24H20F6N5Na2O7PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :713.45HIF-2α-IN-5
CAS :<p>HIF-2α-IN-5 is a potent HIF-2α inhibitor with an IC 50 of < 50 nM [1].</p>Formule :C15H12F4O3S2Couleur et forme :SolidMasse moléculaire :380.389-cis-β-Carotene
CAS :<p>9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal.</p>Formule :C40H56Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :536.87TAK-828F
CAS :<p>TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.</p>Formule :C28H32FN3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.57EGFR-IN-35
CAS :<p>EGFR-IN-35, an acrylamide-based EGFR inhibitor, shows promise for EGFR mutation-related cancers like NSCLC.</p>Formule :C25H24ClN7O2Couleur et forme :SolidMasse moléculaire :489.96MA242 free base
CAS :<p>MA242 free base is a dual MDM2/NFAT1 inhibitor that triggers apoptosis in pancreatic cancer cells.</p>Formule :C24H20ClN3O3SCouleur et forme :SolidMasse moléculaire :465.95MtTMPK-IN-9
<p>MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.</p>Formule :C25H26N6O7Couleur et forme :SolidMasse moléculaire :522.51Novokinin
CAS :<p>Angiotensin AT2 receptor agonist</p>Formule :C39H61N11O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :795.97ddCTP trisodium
<p>ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.</p>Formule :C9H13N3Na3O12P3Couleur et forme :SolidMasse moléculaire :517.1FNC-TP trisodium
<p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>Formule :C9H11FN6Na3O13P3Couleur et forme :SolidMasse moléculaire :592.112R,4R-Sacubitril
CAS :2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.Formule :C24H29NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.49CB-7646
CAS :<p>CB-7646 is a stable trimelamol (TM) analogue, which is an antitumor agent.</p>Formule :C8H16N6O2Couleur et forme :SolidMasse moléculaire :228.25JAK3-IN-13
<p>JAK3-IN-13: Oral JAK3 inhibitor, selective & potent. Acts on NK1, JNK2, JNK3, Tyk2. Anti-tumor. IC50: JNK3, 8 nM; Tyk2, 365 nM; JNK2, 2039 nM; NK1, 4728 nM.</p>Formule :C25H33ClN6O5Couleur et forme :SolidMasse moléculaire :533.02KMH-233
CAS :<p>KMH-233 effectively blocks LAT1, inhibiting L-leucine uptake and cell growth, boosting betastatin and cisplatin efficacy at 25 μM.</p>Formule :C32H25N7O5Couleur et forme :SolidMasse moléculaire :587.58Marizomib
CAS :Marizomib is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L, CT-T-laspase-like, and trypsin-like 20S proteasomes.Cost-effective and quality-assured.Formule :C15H20ClNO4Degré de pureté :98.03% - 99.41%Couleur et forme :SolidMasse moléculaire :313.78BI-1388
CAS :<p>BI-1388 is a potent HCV NS3 protease inhibitor; halts replication across genotypes, including D168V/R155K mutants.</p>Formule :C41H53N7O9SCouleur et forme :SolidMasse moléculaire :819.97Calphostin A
CAS :<p>Calphostins, from Cladosporium fungus, inhibit PKC; calphostin C is most potent, used as a biochemical tool.</p>Formule :C44H38O12Couleur et forme :SolidMasse moléculaire :758.77A-9758
CAS :<p>A-9758: RORγt selective inverse agonist, IC50 5nM, inhibits IL-17A, Th17, and treats psoriasis.</p>Formule :C25H23Cl2F3N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.36AZD0424
CAS :<p>AZD0424: oral Src/Abl kinase inhibitor; potential anticancer; induces apoptosis, cell cycle arrest in lymphoma.</p>Formule :C25H29ClN6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :528.99AMG-548 hydrochloride
<p>AMG-548 hydrochloride: orally active, p38α inhibitor (Ki=0.5 nM), 1000x less for p38γ/δ, also blocks TNFα (IC50=3 nM) & inhibits casein kinase 1 δ/ε.</p>Formule :C29H28ClN5OCouleur et forme :SolidMasse moléculaire :498.02Anti-inflammatory agent 18
<p>Anti-inflammatory agent 18: NO activity blocker (IC50: 15.94 μM), hampers HMGB1-induced inflammation, potential for COVID-19, sepsis study.</p>Formule :C30H50O6Couleur et forme :SolidMasse moléculaire :506.71JTZ-951 HCl
CAS :<p>JTZ-951 is a potent and orally active inhibitor of hypoxia inducible factor prolyl hydroxylase (PHD).</p>Formule :C17H17ClN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.79SIK1 activator 1
CAS :<p>SIK1 activator 1 boosts SIK1 phosphorylation, reduces type 2 diabetes hyperglycemia, and inhibits liver gluconeogenesis.</p>Formule :C23H32O6Couleur et forme :SolidMasse moléculaire :404.50EGFR-IN-24
<p>EGFR-IN-24 is a potent inhibitor of EGFR and inhibits EGFR (del19/T790M/C797S) and EGFR (L858R/T790M/C797S).</p>Formule :C30H35FN6O3Couleur et forme :SolidMasse moléculaire :546.64Thalicarpine
CAS :<p>Thalicarpine, a natural anticancer alkaloid, inhibits p-glycoprotein and induces DNA damage, arresting cell cycle.</p>Formule :C41H48N2O8Couleur et forme :SolidMasse moléculaire :696.83FXIa-IN-8
<p>FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.</p>Couleur et forme :SolidCap-dependent endonuclease-IN-6
CAS :<p>Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.</p>Formule :C23H21N3O3SCouleur et forme :SolidMasse moléculaire :419.5Acyline
CAS :<p>Acyline, a GnRH antagonist, suppresses gonadotropins and testosterone in animals and maintains the effect for 2 weeks in men with one dose.</p>Formule :C80H102ClN15O14Couleur et forme :SolidMasse moléculaire :1533.21Ici D1542
CAS :Ici D1542: potent TXS inhibitor & TXA2 receptor antagonist, effective thromboxane blocker in vitro.Formule :C25H30N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.51JH295 hydrate
<p>JH295 hydrate: potent, irreversible Nek2 inhibitor (IC50 = 770 nM), selective, doesn't target Cdk1, Aurora B or Plk1.</p>Formule :C18H18N4O3Couleur et forme :SolidMasse moléculaire :338.36
