Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.542 produits)
- Apoptose(5.816 produits)
- Cycle cellulaire/point de contrôle(4.466 produits)
- Chromatine/Épigénétique(2.252 produits)
- Signalisation du cytosquelette(1.381 produits)
- Altération de l'ADN/réparation de l'ADN(2.830 produits)
- Endocrinologie/Hormones(3.518 produits)
- Enzyme(3.640 produits)
- GPCR/G-Protéine(8.362 produits)
- Immunologie et Inflammation(3.540 produits)
- Virus de la grippe(296 produits)
- Signalisation JAK/STAT(405 produits)
- Signalisation MAPK(1.201 produits)
- Transporteur membranaire/Canal ionique(2.809 produits)
- Métabolisme(9.462 produits)
- Microbiologie/Virologie(7.003 produits)
- Neuroscience(9.942 produits)
- Autres inhibiteurs(37.827 produits)
- Oxydation-Réduction(40 produits)
- Signalisation PI3K/Akt/mTOR(1.399 produits)
- Protéases/Protéasome(1.598 produits)
- Cellules souche et Dérivés(830 produits)
- Tyrosine Kinase/Adaptateurs(2.012 produits)
- Ubiquitination(1.651 produits)
Affichez 16 plus de sous-catégories
66618 produits trouvés pour "Inhibiteurs"
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LH secretion antagonist 1
CAS :<p>LH secretion antagonist 1 is an antagonist of luteinizing hormone secretion with analgesic activity.</p>Formule :C18H24ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :321.84NLRP3/AIM2-IN-1
<p>NLRP3/AIM2-IN-1 is an inhibitor of thermal sepsis (IC50 = 3.136 ± 0.7667 μM).</p>Formule :C15H16BNO4Couleur et forme :SolidMasse moléculaire :285.1LRRK2-IN-3
CAS :<p>LRRK2-IN-3: potent, selective oral LRRK2 blocker, BBB-penetrant, IC50 of 0.6 nM in hPBMCs, for Parkinson's research.</p>Formule :C25H29ClF2N6O2Couleur et forme :SolidMasse moléculaire :518.99FGI-106
CAS :<p>FGI-106 combats Ebola, Rift Valley, Dengue Fever, HCV, and HIV-1; EC50s range from 100-900 nM.</p>Formule :C28H38N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.64DS17701585
<p>DS17701585: Oral EP300/CBP inhibitor; potent on CBP, EP300, H3K27, & SOX2; useful for cancer research.</p>Formule :C24H26N4O5SCouleur et forme :SolidMasse moléculaire :482.55GNE-886
CAS :<p>GNE-886 has a wide range of applications in life science related research.</p>Formule :C28H30N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.59Gabaculine HCl
CAS :<p>Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.</p>Formule :C7H10ClNO2Couleur et forme :SolidMasse moléculaire :175.61GSK065
CAS :<p>GSK065 is a potent inhibitor of kynurenine-3-monooxygenase (KMO).</p>Formule :C17H15ClN2O4Couleur et forme :SolidMasse moléculaire :346.77Enprostil
CAS :<p>Enprostil: synthetic PGE2 analog, reduces gastric acid, protects mucosa, lowers post-meal gastrin, treats ulcers effectively and safely.</p>Formule :C23H28O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.46PRMT5-IN-1
CAS :<p>PRMT5-IN-1 is a covalent inhibitor of protein arginine methyltransferase 5 (PRMT5)(IC50 of 11 nM for PRMT5/MEP50).</p>Formule :C19H19ClN4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :418.83Topo I-IN-1
<p>Topo I-IN-1 (14d) is a powerful Topo I inhibitor with antitumor effects and DNA intercalation, inducing apoptosis.</p>Formule :C20H14BrN3O2Couleur et forme :SolidMasse moléculaire :408.25MDL-28050
CAS :<p>MDL-28050 is a synthetic analog of hirudin 55-65 C-terminal fragment and a peptide inhibitor.</p>Formule :C61H88N10O23Couleur et forme :SolidMasse moléculaire :1329.4Homodestcardin
CAS :<p>Homodestcardin: cyclic depsipeptide from T. roseum with immunosuppressant properties; inhibits mouse T cell proliferation.</p>Formule :C32H55N5O7Couleur et forme :SolidMasse moléculaire :621.81Elocalcitol
CAS :<p>Elocalcitol is a calcitriol analog for inhibition of prostate cell growth.</p>Formule :C29H43FO2Couleur et forme :SolidMasse moléculaire :442.65Steroid sulfatase-IN-4
<p>Steroid sulfatase-IN-4 irreversibly inhibits human STS with a 25 nM IC50, useful for endometriosis research.</p>Formule :C19H17ClN2O5SCouleur et forme :SolidMasse moléculaire :420.87RMI-18341
CAS :<p>RMI-18341 is a Testosterone 5 alpha reductase inhibitor.</p>Formule :C22H34N2O2Couleur et forme :SolidMasse moléculaire :358.52SIK1 activator 1
CAS :<p>SIK1 activator 1 boosts SIK1 phosphorylation, reduces type 2 diabetes hyperglycemia, and inhibits liver gluconeogenesis.</p>Formule :C23H32O6Couleur et forme :SolidMasse moléculaire :404.50DMP 728
CAS :<p>DMP 728 is an antagonist of Glycoprotein IIb-IIIa.</p>Formule :C26H40N8O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :656.71(S)-MALT1-IN-5
CAS :<p>(S)-MALT1-IN-5: Potent MALT1 protease inhibitor, may help in abnormal T/B-cell signalling and MALT1-linked diseases.</p>Formule :C17H17ClF2N6O3Couleur et forme :SolidMasse moléculaire :426.80Urease-IN-1
<p>Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).</p>Formule :C17H12BrFN4O2SCouleur et forme :SolidMasse moléculaire :435.27YKL-1-116
CAS :<p>YKL-1-116 is an effective, selective, and covalent CDK7 inhibitor.</p>Formule :C34H38N8O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :606.72Pociredir
CAS :<p>Pociredir (FTX-6058), a potent EED inhibitor (KD=0.163 nM), may help in SCD research.</p>Formule :C22H18FN5O2Couleur et forme :SolidMasse moléculaire :403.41Nolpitantium besilate
CAS :<p>Nolpitantium besilate is a neurokinin-1 receptor antagonist.</p>Formule :C43H50Cl2N2O5SCouleur et forme :SolidMasse moléculaire :777.84URAT1 inhibitor 3
<p>URAT1 inhibitor 3: potent oral URAT1 blocker, IC50=0.8 nM, for gout/hyperuricemia study.</p>Formule :C14H8Cl2N2O2Couleur et forme :SolidMasse moléculaire :307.13Cbl-b-IN-2
CAS :<p>Cbl-b-IN-2 is an oral E3 enzyme inhibitor for immune-modulated diseases and cancer research.</p>Formule :C29H30F5N5O2Couleur et forme :SolidMasse moléculaire :575.57MEIS-IN-1
CAS :<p>MEIS-IN-1 is a potent MEIS inhibitor that induces the expansion of hematopoietic stem cells in mice and humans.</p>Formule :C24H21F3N2O4Couleur et forme :SolidMasse moléculaire :458.43KT5926
CAS :<p>KT5926 selectively inhibits myosin light chain kinase and NGF-dependent neurite growth; it's a K-252a analogue.</p>Formule :C30H27N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :525.55Sekikaic Acid
CAS :<p>Sekikaic acid, a phenolic lichen metabolite in H. obscurata, has antioxidant and antiviral properties, inhibiting MLL1-CBP.</p>Formule :C22H26O8Couleur et forme :SolidMasse moléculaire :418.44BAY-3153
CAS :<p>BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) .</p>Formule :C25H29Cl2N3O4Couleur et forme :SolidMasse moléculaire :506.42Vanin-1-IN-3
<p>Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC 50 of 0.038 μM [1].</p>Formule :C17H22F3NO5Couleur et forme :SolidMasse moléculaire :377.36LX2761
CAS :<p>LX2761 is a stable inhibitor for SGLT1/2 with IC50s of 2.2/2.7 nM; it targets SGLT1 in the GI tract.</p>Formule :C32H47N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :601.80PI4KIIIbeta-IN-11
CAS :<p>PI4KIIIbeta-IN-11 is a PI4KIIIβ inhibitor (mean pIC50=9.1) that can be used to study diseases caused by RNA viruses and Plasmodium falciparum.</p>Formule :C33H39N7O3Couleur et forme :SolidMasse moléculaire :581.71MAO-B-IN-5
CAS :<p>MAO-B-IN-5: potent, selective oral MAO-B inhibitor, IC50=0.204μM, potential for Parkinson's research.</p>Formule :C19H21FN2O2Degré de pureté :97.68%Couleur et forme :SolidMasse moléculaire :328.38PRMT5-IN-19
PRMT5-IN-19 is a potent, selective PRMT5 inhibitor with IC50 of 23.9 nM and 47 nM, showing anti-cancer activity by inducing apoptosis.Formule :C25H24N4OCouleur et forme :SolidMasse moléculaire :396.48LY2934747
CAS :<p>LY2934747 is a novel, potent, and systemically bioavailable mGlu2/3 receptor agonist, exhibiting both antipsychotic and analgesic properties in vivo.</p>Formule :C10H13NO4Couleur et forme :SolidMasse moléculaire :211.21RO5461111
CAS :<p>RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.</p>Formule :C27H24F6N4O4SCouleur et forme :SolidMasse moléculaire :614.56(S)-JDQ-443
CAS :<p>(S)-JDQ-443, an isomer of JDQ-443, is a selective, potent oral KRAS G12C inhibitor with antitumor properties.</p>Formule :C29H28ClN7OCouleur et forme :SolidMasse moléculaire :526.03CYP2C19-IN-1
<p>CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.</p>Formule :C26H26N2O6SCouleur et forme :SolidMasse moléculaire :494.56Akt/NF-κB/JNK-IN-1
<p>Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signalling pathways.Akt/NF-κB/JNK-IN-1 exhibits an inhibitory effect on nitric oxide</p>Formule :C22H22N2O6Couleur et forme :SolidMasse moléculaire :410.42OP-5244 sodium
<p>OP-5244 sodium: potent oral CD73 inhibitor (IC50: 0.25 nM), potential in cancer research by hindering adenosine, reversing immunosuppression.</p>Formule :C19H28ClN5NaO9PCouleur et forme :SolidMasse moléculaire :559.87PF-07202954
CAS :<p>PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM against</p>Formule :C22H23FN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.45Quinagolide Free Base
CAS :<p>Quinagolide Free Base is a non-ergot dopamine D(2)-agonist.</p>Formule :C20H33N3O3SCouleur et forme :SolidMasse moléculaire :395.56AM Toxin II
CAS :<p>AM Toxin II is a Cyclic tetradepsipeptide isolated from Alternaria mali.</p>Formule :C22H29N3O5Couleur et forme :SolidMasse moléculaire :415.49HDAC-IN-37
<p>HDAC-IN-37 inhibits HDACs 1, 3, 8, & 6, induces histone acetylation, halts G1 to S phase, and triggers early apoptosis.</p>Formule :C23H24ClN7OCouleur et forme :SolidMasse moléculaire :449.94BMS-681
CAS :<p>BMS-681 is a CCR2 antagonist blocking chemokine binding, aiding control of inflammatory and neurodegenerative diseases.</p>Formule :C26H36F3N5OCouleur et forme :SolidMasse moléculaire :491.59NI-Pano
<p>NI-Pano (CH-03) is a novel hypoxia-activated KDAC inhibitor capable of O2-dependent release of the compound panobinostat.</p>Formule :C26H28N6O4Couleur et forme :SolidMasse moléculaire :488.54CD73-IN-2
<p>CD73-IN-2 is a potent inhibitor of CD73 (IC50: 0.09 nM).</p>Formule :C17H25ClN5O7PCouleur et forme :SolidMasse moléculaire :477.84ZK-Thiazolidinone
CAS :<p>ZK-Thiazolidinone (TAL), ATP-competitive PLK1 inhibitor, disrupts cell division processes in vitro and in vivo, targeting human/mouse tumors.</p>Formule :C23H26F3N5O2SCouleur et forme :SolidMasse moléculaire :493.55BChE-IN-2
<p>BChE-IN-2, a pyrimidine/pyridine derivative, potently inhibits BChE (Ki 0.099 μM) and shows promise in AD research.</p>Formule :C22H31N5Couleur et forme :SolidMasse moléculaire :365.52FK-3657
CAS :<p>FK-3657 is a non-peptide antagonist of bradykinin (BK)-B2 receptor.</p>Formule :C30H27Cl2N5O4Couleur et forme :SolidMasse moléculaire :592.47Amdinocillin methylacetate
CAS :<p>Amdinocillin methylacetate is a Synthetic penicillin.</p>Formule :C18H27N3O4SCouleur et forme :SolidMasse moléculaire :381.49IL-17 modulator 1 disodium
CAS :<p>Potent, orally active IL-17 Modulator 1 (disodium) from patent WO 2020127685, used in psoriasis and arthritis research.</p>Formule :C28H37N6NaO6PCouleur et forme :SolidMasse moléculaire :607.604WF-47-JS03
<p>WF-47-JS03: RET kinase inhibitor, crosses blood-brain barrier, 500x more selective for KDR, IC50: 1.7 nM in Ba/F3 cells, 5.3 nM in LC-2/ad lung cancer cells.</p>Formule :C30H38N6O2Couleur et forme :SolidMasse moléculaire :514.66Gemilukast
CAS :<p>Gemilukast (ONO-6950) is a cysteinyl leukotriene 1 and 2 receptor inhibitor that inhibits bronchoconstriction and is used in the treatment of asthma.</p>Formule :C36H37F2NO5Degré de pureté :98.27% - 99.5%Couleur et forme :SolidMasse moléculaire :601.68MRS4738
<p>MRS4738 is a potent antagonist with high affinity for the P2Y14R receptor. It demonstrates in vivo anti-hyperallodynic and antiasthmatic activity [1].</p>Formule :C30H24F3NO2Couleur et forme :SolidMasse moléculaire :487.51BAY-899
CAS :<p>BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.</p>Formule :C25H19F2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.45RGB-286638
CAS :<p>RGB-286638 inhibits multiple CDKs and GSK-3β, TAK1, Jak2, MEK1 with IC50s as low as 1-54 nM.</p>Formule :C29H37Cl2N7O4Couleur et forme :SolidMasse moléculaire :618.55GPR84 antagonist 3
CAS :<p>Potent GPR84 antagonist 3 (compound 42), pIC50 8.28, inhibits GTPγS, with good pharmacokinetics.</p>Formule :C29H27N5OCouleur et forme :SolidMasse moléculaire :461.56cis-4-Br-2,5-F2-PCPA
<p>cis-4-Br-2,5-F2-PCPA (S1024) blocks LSD1/LSD2 (Ki: 94 nM/8.4 μM), hinders cancer stem cell growth, raises H3K4me2 in CCRF-CEM cells.</p>Formule :C9H8BrF2NCouleur et forme :SolidMasse moléculaire :248.07PPARα/γ agonist 1
<p>PPARα/γ agonist 1 is a potent and dual PPARα/γ partial agonist which is a promising prototype for the research of dyslipidemia and diabetes.</p>Formule :C18H19NO2Couleur et forme :SolidMasse moléculaire :281.35Keap1-Nrf2-IN-1 TFA
<p>Keap1-Nrf2-IN-1 TFA (compound35) is a potent inhibitor (IC50: 43 nM) protecting against acetaminophen liver damage.</p>Formule :C26H25F3N2O9SCouleur et forme :SolidMasse moléculaire :598.54Carbonic anhydrase inhibitor 4
<p>CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.</p>Formule :C21H18N2O4SCouleur et forme :SolidMasse moléculaire :394.44CB 30900
CAS :<p>CB30900 is a novel and effective thymidylate synthase inhibitor.</p>Formule :C31H32FN5O9Couleur et forme :SolidMasse moléculaire :637.61BET-IN-1
<p>BET-IN-1 is a potent inhibitor of BET, exhibiting good brain permeability and a reasonable metabolic stability.</p>Formule :C23H24ClFN4O3SCouleur et forme :SolidMasse moléculaire :490.98AZD4625
<p>AZD4625 (Compound 21) is a selective, potent, orally active, covalent and mutagenic mutant GTPaseKRASG12C inhibitor.</p>Formule :C24H21ClF2N4O3Couleur et forme :SolidMasse moléculaire :486.9PCSK9-IN-17
CAS :<p>PCSK9-IN-17 is a PCSK9 inhibitor utilized in the research of cholesterol metabolism.</p>Formule :C16H19N5OSCouleur et forme :SolidMasse moléculaire :329.42FNDR-20123
<p>FNDR-20123: First safe, effective anti-malarial HDAC inhibitor for Plasmodium (IC50: 31 nM) & human HDACs, with nanomolar potency across several subtypes.</p>Formule :C21H24ClN5O2Couleur et forme :SolidMasse moléculaire :413.9Revexepride
CAS :<p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>Formule :C21H32ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :425.95Antibacterial agent 69
<p>Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 μM).</p>Formule :C24H19N3O4SCouleur et forme :SolidMasse moléculaire :445.49DNA crosslinker 4 dihydrochloride
CAS :<p>DNA Crosslinker 4 binds DNA's minor groove, inhibits NCI-H460, A2780, MCF-7 cancer cells, and is used in cancer research.</p>Formule :C16H24Cl2N8OCouleur et forme :SolidMasse moléculaire :415.32GSK5852
<p>GSK5852, an HCV NS5B inhibitor, has IC50 of 50 nM; potently fights HCV with EC50 of 3.0 nM for GT1a and 1.7 nM for GT1b.</p>Formule :C27H27BF2N2O6SCouleur et forme :SolidMasse moléculaire :556.39Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Formule :C21H27N3SCouleur et forme :SolidMasse moléculaire :353.52U 80215
CAS :<p>U 80215 is an enzyme-competitive inhibitor.</p>Formule :C42H60N8O6SCouleur et forme :SolidMasse moléculaire :805.04Domitroban
CAS :<p>Domitroban, also known as S-145, is a thromboxane (Tx) A2-receptor antagonist with partial agonistic activity in vascular smooth muscle.</p>Formule :C20H27NO4SCouleur et forme :SolidMasse moléculaire :377.5TAK-828F
CAS :<p>TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.</p>Formule :C28H32FN3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.57A1AR antagonist 1
<p>Compound 18g, a potent A1AR blocker with Ki: 2.08 nM (hA1), 6.91 nM (hA2A), 31.2 nM (hA2B).</p>Formule :C18H14N4OCouleur et forme :SolidMasse moléculaire :302.33Human carbonic anhydrase II-IN-1
<p>Compound S-13: Potent hCA II inhibitor, Kis 4.4, 9.2, 480.2, 14.7 nM for hCA II, I, IV, IX. Used in glaucoma research.</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5AChE-IN-22
<p>AChE-IN-22 (10q) selectively inhibits AChE (IC50: 0.88 μM), less on BuChE (IC50: 10 μM), targets CAS and PAS, useful in Alzheimer's research.</p>Formule :C21H20N4O5SCouleur et forme :SolidMasse moléculaire :440.47Carazostatin
CAS :<p>Carazostatin is an antioxidant, free radical scavenger, and potent lipid peroxidation inhibitor.</p>Formule :C20H25NODegré de pureté :98%Couleur et forme :Pale Yellow SolidMasse moléculaire :295.42JTZ-951 HCl
CAS :<p>JTZ-951 is a potent and orally active inhibitor of hypoxia inducible factor prolyl hydroxylase (PHD).</p>Formule :C17H17ClN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.79Serlopitant
CAS :<p>Serlopitant is a selective antagonist of Neurokinin-1 (NK-1) receptor.</p>Formule :C29H28F7NO2Couleur et forme :SolidMasse moléculaire :555.53MRTX-EX185
<p>MRTX-EX185 inhibits GDP-KRAS/G12D; IC50=90 nM on G12D. It also binds GDP-HRAS.</p>Formule :C33H33FN6O2Couleur et forme :SolidMasse moléculaire :564.65CaMKIIα-IN-1
<p>CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.</p>Formule :C14H11ClO4Couleur et forme :SolidMasse moléculaire :278.69Cyclic-di-GMP sodium
<p>c-di-GMP sodium: STING activator, regulates bacteria biofilm, motility, virulence.</p>Formule :C20H24N10NaO14P2Couleur et forme :SolidMasse moléculaire :713.0846412(S)-HETE
CAS :<p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47Purine phosphoribosyltransferase-IN-1
<p>Compound (S,R)-48 inhibits Pf, Pv, & Tbr PRT with Ki of 50, 20, 2 nM.</p>Formule :C11H15N5Na4O10P2Couleur et forme :SolidMasse moléculaire :531.17HIF-1/2α-IN-1
<p>HIF-1/2α-IN-1, an orally active compound, functions as an inhibitor of HIF-2α.</p>Formule :C17H16N6O4Couleur et forme :SolidMasse moléculaire :368.35PF-06751979
CAS :PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).Formule :C18H19F2N5O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.5C-di-IMP
CAS :<p>Cyclic-di-IMP (C-di-IMP), a STING agonist, serves as a research tool in tumor studies.</p>Formule :C20H22N8O14P2Couleur et forme :SolidMasse moléculaire :660.38GDC-6036-NH
CAS :<p>GDC-6036-NH is a precursor of compound 17a /b, which is a RAS inhibitor that can be used in cancer research.</p>Formule :C26H30ClF4N7ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :568.01VEGFR-2-IN-14
<p>VEGFR-2-IN-14 (Compound 5) is a potent inhibitor of VEGFR-2, which inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.</p>Formule :C24H23N3O3SCouleur et forme :SolidMasse moléculaire :433.52Marizomib
CAS :Marizomib is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L, CT-T-laspase-like, and trypsin-like 20S proteasomes.Cost-effective and quality-assured.Formule :C15H20ClNO4Degré de pureté :98.03% - 99.41%Couleur et forme :SolidMasse moléculaire :313.78Iralukast (CGP 45715A)
CAS :<p>Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.</p>Formule :C38H37F3O8SCouleur et forme :SolidMasse moléculaire :710.76DNA crosslinker 3 dihydrochloride
CAS :<p>Compound 1: a DNA minor groove binder with 1.4°C ΔTm; useful in cancer research.</p>Formule :C15H22Cl2N8OCouleur et forme :SolidMasse moléculaire :401.29BMT-052
CAS :<p>BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).</p>Formule :C30H17D9F4N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :635.61KY-02327 acetate
<p>KY-02327 acetate inhibits Dvl-CXXC5, stabilizes Wnt/β-catenin signaling, and enhances osteoblast differentiation.</p>Formule :C22H31N3O6Couleur et forme :SolidMasse moléculaire :433.5UK-432097
CAS :<p>UK 432097 is an adenosine A2A agonist.</p>Formule :C40H47N11O6Couleur et forme :SolidMasse moléculaire :777.8711-Oxahomoaminopterin
CAS :<p>11-Oxahomoaminopterin exhibits antifolate activity against two folate-requiring microorganisms and inhibited Lactobacillus casei DHFR.</p>Formule :C20H21N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.42CS-0777
CAS :<p>CS-0777 is a potent, selective, and orally active S1P1 agonist (sphingosine 1-phosphate receptor modulator).</p>Formule :C21H31N2O5PCouleur et forme :SolidMasse moléculaire :422.45Lasonolide A
CAS :<p>Lasonolide A, an anticancer compound from Forcepia sponge, shows nanomolar growth inhibition and unique cytotoxicity in the NCI 60-cell-line screen.</p>Formule :C41H60O9Couleur et forme :SolidMasse moléculaire :696.91AM8936
<p>AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.</p>Formule :C25H33NO3Couleur et forme :SolidMasse moléculaire :395.53RAD51-IN-6
CAS :<p>RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)</p>Formule :C27H40N3O5PSCouleur et forme :SolidMasse moléculaire :549.66Ceclazepide
CAS :<p>Ceclazepide is an antagonist of cholecystokinin receptor.</p>Formule :C30H32N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.61P-gp inhibitor 2
CAS :<p>Potent P-gp inhibitor 2 reverses Doxorubicin resistance in colorectal carcinoma cells with IC50 of 0.22 µM.</p>Formule :C29H26N2O6Couleur et forme :SolidMasse moléculaire :498.53Pelecopan
CAS :<p>Pelecopan (BCX9930), an oral complement factor D inhibitor, prevents hemolysis in PNH (IC50=14.3 nM).</p>Formule :C23H19FN2O4Couleur et forme :SolidMasse moléculaire :406.41XN methyl pyrazole
<p>XN methyl pyrazole exhibits beneficial effects on diet-induced obesity and enhances energy expenditure in mice fed with a high-fat diet [1].</p>Formule :C22H24N2O4Couleur et forme :SolidMasse moléculaire :380.44Oral antiplatelet agent 1
CAS :<p>Oral antiplatelet agent 1 is a potent antiplatelet agent with an IC50 of 2.94 μM in vitro.</p>Formule :C23H24N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.53ent-8-iso-15(S)-Prostaglandin F2α
CAS :<p>Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid.</p>Formule :C20H34O5Couleur et forme :SolidMasse moléculaire :354.48AChE/GSK-3β-IN-1
CAS :<p>AChE/GSK-3β-IN-1 is a potent dual AChE/GSK-3β inhibitor that crosses the blood-brain barrier and acts on hAChE (IC50: 1.2 nM), hBChE (IC50: 149.8 nM) and hGSK-</p>Formule :C31H35N7O3SCouleur et forme :SolidMasse moléculaire :585.72Guraxetan
<p>Guraxetan can be used in the synthesis of the antitumour drug Lutetium (177Lu) zadavotide Guraxetan.</p>Formule :C20H34N4O9Couleur et forme :SolidMasse moléculaire :474.51Alpibectir
CAS :<p>Alpibectir has antibacterial activity [1].</p>Formule :C12H14F6N2O2Couleur et forme :SolidMasse moléculaire :332.24TRK-IN-12
CAS :<p>TRK-IN-12 (9e), a macrocyclic TRK inhibitor (G595R IC50=13.1 nM), outperforms LOXO-101 in Ba/F3-NTRK1 cells.</p>Formule :C18H19ClFN5O3SCouleur et forme :SolidMasse moléculaire :439.89PF-5177624
CAS :<p>PF-5177624 is a selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells.</p>Formule :C25H25FN8O2Couleur et forme :SolidMasse moléculaire :488.52C-11
CAS :C-11 is a tubulin inhibitor and acts as an ADC cytotoxin with cytotoxicity for carcinoma cell lines.Formule :C38H58N6O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :742.97DNA-PK-IN-2
CAS :<p>DNA-PK-IN-2 is an inhibitor of the DNA-PK enzyme complex, useful in cancer research.</p>Formule :C20H23N5O3Couleur et forme :SolidMasse moléculaire :381.43HDAC-IN-35
<p>HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.</p>Formule :C17H13ClF3N3O3Couleur et forme :SolidMasse moléculaire :399.75Ambuic acid
CAS :<p>Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.</p>Formule :C19H26O6Couleur et forme :SolidMasse moléculaire :350.41BMS-751324
CAS :<p>BMS-751324: p38α MAPK inhibitor with carbamyl-methyl, esters, phosphate from HPA. Reduces rat arthritis swelling and TNFα.</p>Formule :C32H35N6O10PCouleur et forme :SolidMasse moléculaire :694.63EGFR-IN-45
<p>EGFR-IN-45: Strong EGFR/CDK2 inhibitor (IC50s: 0.4 & 1.6 μM), halts cancer cell cycle pre-G1, prompts apoptosis, also targets Topo I/II.</p>Formule :C28H23N7OCouleur et forme :SolidMasse moléculaire :473.53Zorubicin
CAS :<p>Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.</p>Formule :C34H35N3O10Couleur et forme :SolidMasse moléculaire :645.66PD-1/PD-L1-IN-13
<p>PD-1/PD-L1-IN-13 is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM for PD-1/PD- L1 interaction.PD-1/PD-L1-IN-13 promotes CD8+ T-</p>Formule :C36H34ClF2N3O9Couleur et forme :SolidMasse moléculaire :726.12Antimalarial agent 3
<p>Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.</p>Formule :C15H16BrN3O2Couleur et forme :SolidMasse moléculaire :350.21ST362
CAS :<p>ST362, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.</p>Formule :C25H21NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.5MY-875
<p>MY-875 inhibits microtubule formation, binds like colchicine (IC50: 0.92 μM), activates Hippo pathway, and induces apoptosis with anticancer properties.</p>Formule :C21H25NO6Couleur et forme :SolidMasse moléculaire :387.43Tilpisertib fosmecarbil
CAS :<p>Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.</p>Formule :C35H36ClN8O7PCouleur et forme :SolidMasse moléculaire :747.14Ro 31-8472
CAS :<p>Ro 31-8472 is an angiotensin-converting enzyme (ACE) inhibitor and an analog of cilazaprilat.</p>Formule :C20H27N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.44DLK-IN-1
CAS :DLK-IN-1: Oral DLK (MAP3K12) inhibitor, Ki=3nM, effective in Alzheimer's model, CNS permeable, well-tolerated with sustained brain levels.Formule :C20H24F3N5O2Couleur et forme :SolidMasse moléculaire :423.43Aβ-IN-2
<p>Aβ-IN-2 is a peptide inhibitor of Aβ1-42.</p>Formule :C37H51NOCouleur et forme :SolidMasse moléculaire :525.81Dehydrocrenatidine
CAS :<p>Dehydrocrenatidine (Kumujian G) is an inhibitor of JAK and induces cell apoptosis.</p>Formule :C15H14N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :254.28Anti-Aβ agent 1A
<p>Anti-Aβ agent 1A is a potent anti-amyloid-β agent.</p>Formule :C35H49NO4Couleur et forme :SolidMasse moléculaire :547.77YM-60828 dihydrochloride
CAS :<p>YM-60828 dihydrochloride is a Factor Xa (FXa) inhibitor and anticoagulant used in the treatment of venous thromboembolic disease.</p>Formule :C27H33Cl2N5O5SCouleur et forme :SolidMasse moléculaire :610.55Tubulin polymerization-IN-6
<p>Compound 5f, a potent tubulin polymerization inhibitor (IC50 = 1.09 μM), blocks cell migration, tube formation, and has anti-angiogenic effects.</p>Formule :C19H21NO7Couleur et forme :SolidMasse moléculaire :375.37PD-149163
CAS :<p>PD-149163: brain-penetrating, selective NTR1 agonist; shows pro-cognitive, anti-psychotic, anxiolytic effects.</p>Formule :C42H71N9O6Couleur et forme :SolidMasse moléculaire :798.07QPX7728 methoxy acetoxy methy ester
CAS :QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.Formule :C14H14BFO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.07Kaitocephalin
CAS :<p>Kaitocephalin: naturally occurring, non-selective antagonist blocking glutamate receptors, made by Eupenicillium shearii fungus.</p>Formule :C18H21Cl2N3O9Couleur et forme :SolidMasse moléculaire :494.28SCP1-IN-2
<p>SCP1-IN-2: potent, selective SCP1 inhibitor; induces REST degradation, hinders its activity, may study REST-driven glioblastoma growth.</p>Formule :C19H17F3N2O6S2Couleur et forme :SolidMasse moléculaire :490.47(±)-ANAP hydrochloride
CAS :<p>'(±)-ANAP hydrochloride, an unnatural amino acid analog of prodan, serves as a fluorescent probe with enhanced environmental sensitivity.'</p>Formule :C15H17ClN2O3Couleur et forme :SolidMasse moléculaire :308.76NLRP3-IN-7
<p>NLRP3-IN-7 (Compound 36) is a selective inhibitor of the NLRP3 inflammasome and is able to assemble the NLRP3 inflammasome.</p>Formule :C18H15ClN2O4S3Couleur et forme :SolidMasse moléculaire :454.97DC1SMe
CAS :<p>DC1, a CC-1065-like ADC cytotoxin, is used in cancer-targeting antibody-drug conjugates. DC1Sme, a derivative, has IC50s: 22-250 pm in various cancer cells.</p>Formule :C35H30ClN5O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :684.23DN-F01
<p>DN-F01 exhibits a potent calcium-dependent inhibitory effect on cardiac myofibrillar ATPase activity, with an IC50 of 11 ± 4 nmol/L.</p>Formule :C22H16N2O2Couleur et forme :SolidMasse moléculaire :340.37Cap-dependent endonuclease-IN-7
CAS :<p>Cap-dependent endonuclease-IN-7, a potent CEN inhibitor, blocks viral mRNA synthesis and virus spread, with research use for influenza A, B, C.</p>Formule :C36H28FN3O7SCouleur et forme :SolidMasse moléculaire :665.69GSK2945 hydrochloride
<p>GSK2945 HCl is a specific Rev-erbα antagonist, EC50: 21.5 μM (mouse), 20.8 μM (human), increases cholesterol 7α-hydroxylase.</p>Formule :C20H19Cl3N2O2SCouleur et forme :SolidMasse moléculaire :457.8K027
<p>K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer's disease.</p>Formule :C15H18Br2N4O2Couleur et forme :SolidMasse moléculaire :446.14PX-316
CAS :<p>PX-316: AKT inhibitor, reduces Akt activity by 78% in HT-29 xenografts, effective against MCF-7 and HT-29 cancers, well-tolerated intravenously.</p>Formule :C28H57O10PCouleur et forme :SolidMasse moléculaire :584.72GW-597901 cinnamate
CAS :<p>GW-597901 cinnamate is a long-acting beta(2)-agonist.</p>Formule :C34H46N2O8SCouleur et forme :SolidMasse moléculaire :642.80AMG-222 tosylate
CAS :<p>AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.</p>Formule :C39H47N9O6SCouleur et forme :SolidMasse moléculaire :769.91Asukamycin
CAS :<p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>Formule :C31H34N2O7Couleur et forme :SolidMasse moléculaire :546.61ONO-AE1-259 lysine
CAS :<p>ONO-AE1-259 is a highly selective agonist of prostaglandin e2 receptor (ep2)</p>Formule :C28H49ClN2O6Couleur et forme :SolidMasse moléculaire :545.15Quorum Sensing-IN-1
<p>Quorum Sensing-IN-1 is a small-molecule inhibitor of quorum sensing.</p>Formule :C13H10N2O2S2Couleur et forme :SolidMasse moléculaire :290.36Anti-inflammatory agent 23
<p>Anti-inflammatory agent 23 blocks LPS-induced NO (IC50: 0.449 μM) and binds p65 well.</p>Formule :C34H49NO6Couleur et forme :SolidMasse moléculaire :567.76Metocurine chloride
CAS :<p>Metocurine: a muscle relaxant, not for kidney failure patients as it's kidney-excreted.</p>Formule :C40H48Cl2N2O6Couleur et forme :SolidMasse moléculaire :723.72Antifungal agent 38
<p>Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.</p>Formule :C8H12N2S2Couleur et forme :SolidMasse moléculaire :200.3216,16-Dimethyl prostaglandin E2
CAS :<p>16,16-Dimethyl prostaglandin E2 regulates hematopoietic stem cells via EP2/EP4 and Wnt, taken orally.</p>Formule :C22H36O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.52P7170
CAS :<p>P7170 is an anti-cancer agent active as an mTORC1/C2 and activin receptor-like kinase 1 (ALK1) inhibitor.</p>Formule :C21H16F3N9Couleur et forme :SolidMasse moléculaire :451.42MB-07344 sodium
<p>"MB-07344 sodium is a TR-β agonist with a 2.17 nM Ki, boosts Atorvastatin's cholesterol-lowering effects in various animals."</p>Formule :C19H25NaO5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.36Steroid sulfatase/17β-HSD1-IN-4
<p>Steroid sulfatase/17β-HSD1-IN-4 (compound 37) is a potent dual inhibitor of steroid sulfatase ( STS ) and 17β-hydroxysteroid dehydrogenase type 1 ( 17β HSD1 ).</p>Formule :C18H17N3O4S2Couleur et forme :SolidMasse moléculaire :403.48AKR1C3-IN-7
<p>AKR1C3-IN-7 (Compound 13) is an effective and selective AKR1C3 inhibitor (IC50=0.19 μM). AKR1C3-IN-7 has antitumor activity.</p>Formule :C24H20N2O4Couleur et forme :SolidMasse moléculaire :400.43Aβ42-IN-1
CAS :<p>Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).</p>Formule :C29H27ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :499SH498
CAS :<p>SH498 is a novel Bmi-1-mediated anti-tumor agent with significant anti-proliferative effects.</p>Formule :C27H25F3N2O4Couleur et forme :SolidMasse moléculaire :498.49LSD1-IN-15
<p>LSD1-IN-15 inhibits LSD1, MAO-A/B with IC50s: 0.149, 0.028, 0.327 μM; arrests LNCaP cancer cell growth, IC50 9.9 μM.</p>Formule :C22H20N2OCouleur et forme :SolidMasse moléculaire :328.418-Deazafolic acid
CAS :8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.Formule :C20H20N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.41ACT-672125
CAS :<p>ACT-672125: Potent CXCR3 blocker, may treat autoimmunity, safe with dose-dependent efficacy in lung inflammation.</p>Formule :C25H25F3N10O2SCouleur et forme :SolidMasse moléculaire :586.59TLR4/NF-κB/MAPK-IN-1
CAS :<p>TLR4/NF-κB/MAPK-IN-1 is a novel antineuroinflammatory agent that functions by inhibiting the TLR4/NF-κB/MAPK pathways.</p>Formule :C19H25BrO6Couleur et forme :SolidMasse moléculaire :429.3BET-IN-6
CAS :<p>BET-IN-6: Potent BRD2/4 inhibitor and ligand for PROTAC BRD2/BRD4 degrader-1 synthesis.</p>Formule :C22H20N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.47Anti-inflammatory agent 16
<p>Compound 14 is a peptidomimetic that significantly lowers TNFα, NO, CD40, and CD86, showcasing strong anti-inflammatory effects.</p>Formule :C21H23N5O3Couleur et forme :SolidMasse moléculaire :393.44Cortistatin A
CAS :<p>Cortistatin A is a potent and selective mediator-associated kinase CDK8 and its paralogue CDK19 inhibitor.</p>Formule :C30H36N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :472.62STING agonist-20
CAS :<p>STING agonist-20: potent, aids in XMT-2056 synthesis, used as a cancer vaccine adjuvant.</p>Formule :C36H39N11O8Couleur et forme :SolidMasse moléculaire :753.76Y1 receptor antagonist 1
CAS :<p>Y1 receptor antagonist 1 is an antagonist of neuropeptide Y1 receptor.</p>Formule :C28H33N5O3Degré de pureté :98.17%Couleur et forme :SolidMasse moléculaire :487.59MA242
CAS :<p>MA242 is a nuclear factor of activated T cells 1 (NFAT1) for Pancreatic Cancer Therapy and dual inhibitor of murine double minute 2 (MDM2).</p>Formule :C26H21ClF3N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :579.98Anticancer agent 143
CAS :<p>Anticancer Agent 143 (Compound 369), a potent dual inhibitor targeting PTPN2 and PTP1B, exhibits IC50 values below 2.5 nM.</p>Formule :C19H15BrF2N3O6PS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.34Bleomycin Free Base
CAS :<p>Bleomycin Free Base, a glycopeptide antibiotic, halts DNA function and treats solid tumors.</p>Formule :C55H84N17O21S3Couleur et forme :SolidMasse moléculaire :1415.55ATR-IN-7
CAS :<p>ATR-IN-7 is a potent inhibitor of ATR.</p>Formule :C21H22FN7OCouleur et forme :SolidMasse moléculaire :407.44BAY-693
CAS :<p>BAY-693 is a ERK5 negative control agent with IC50 (ERK5) = 6400 nM. Its analog, BAY-885, is a potent and selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM</p>Formule :C26H30F3N7O2Couleur et forme :SolidMasse moléculaire :529.56Sulprostone
CAS :<p>EP3 and EP1 receptor agonist</p>Formule :C23H31NO7SDegré de pureté :98%Couleur et forme :White To Off-White SolidMasse moléculaire :465.56FAK inhibitor 6
CAS :<p>Compound 26F: potent enzyme inhibitor (IC50=28.2nM), low cytotoxicity (IC50=3.32μM), induces dose-dependent apoptosis in MDA-MB-231, blocks G0/G1 phase.</p>Formule :C25H24FN5O2SCouleur et forme :SolidMasse moléculaire :477.55Bizelesin
CAS :<p>Bizelesin, a synthetic antineoplastic agent, binds DNA, disrupts replication, triggers cell-cycle arrest, and induces senescence.</p>Formule :C43H36Cl2N8O5Couleur et forme :SolidMasse moléculaire :815.7USP7-IN-6
CAS :<p>USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM).</p>Formule :C41H43N7O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :729.89CB2 receptor antagonist 1
CAS :<p>Compound 29 is a potent, CB2-selective antagonist/reverse agonist. Derivatives 23 & 24 offer antinociception; 24 activates cannabinoid/TRPV1 receptors.</p>Formule :C28H47NO3Couleur et forme :SolidMasse moléculaire :445.68Chitin synthase inhibitor 12
<p>Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.</p>Formule :C23H21ClFN3O5Couleur et forme :SolidMasse moléculaire :473.88CYP2C1/CYP2C19-IN-2
<p>CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.</p>Formule :C27H28N2O6SCouleur et forme :SolidMasse moléculaire :508.59SML-10-70-1
CAS :<p>SML-10-70-1 is a Novel Active Site Inhibitor of Oncogenic K-Ras G12C.</p>Formule :C25H42ClN7O13P2Couleur et forme :SolidMasse moléculaire :746.04Leukotriene F-4 sulfone
CAS :<p>Leukotriene F-4 sulfone induces vascular permeability changes.</p>Formule :C28H44N2O10SCouleur et forme :SolidMasse moléculaire :600.72AZD-4121
CAS :<p>AZD-4121 is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.</p>Formule :C36H39F2N3O7SCouleur et forme :SolidMasse moléculaire :695.77Cas9-IN-1
<p>Cas9-IN-1 is a potent inhibitor of Cas9 with an IC50 value of 7.02 μM. Cas9-IN-1 acts by binding apo-Cas9 and blocking the formation of the Cas9:gRNA complex.</p>Formule :C17H11Cl2F3N2O3SCouleur et forme :SolidMasse moléculaire :451.25Henagliflozin
CAS :<p>Henagliflozin (SHR3824): an oral, selective SGLT2 inhibitor, weak on SGLT1.</p>Formule :C22H24ClFO7Couleur et forme :SolidMasse moléculaire :454.87(Rac)-Nebivolol
CAS :<p>(Rac)-Nebivolol, a racemic β1-adrenergic blocker (IC50=0.8 nM), has vasodilatory properties and mitigates ethanol-induced cardiac harm.</p>Formule :C22H25F2NO4Couleur et forme :SolidMasse moléculaire :405.432-Methylsorbinol
CAS :<p>2-Methylsorbinol is a bioactive chemical.</p>Formule :C12H11FN2O3Couleur et forme :SolidMasse moléculaire :250.23Triciferol
CAS :<p>Triciferol is a VDR agonist and HDAC antagonist with 1,25D-like potency, affecting gene targets and tubulin, and shows anti-cancer effects in vitro. IC50=87nM.</p>Formule :C26H39NO4Couleur et forme :SolidMasse moléculaire :429.591Anti-inflammatory agent 12
<p>Pentacyclic triterpene, anti-inflammatory agent 12, inhibits LPS inflammation (IC50: 2.22 μM). May benefit inflammatory disease studies.</p>Formule :C30H50O4Couleur et forme :SolidMasse moléculaire :474.72Desacetylravidomycin
CAS :<p>Desacetylravidomycin is a new inhibitor of IL-4 signal transduction, produced by Streptomyces sp. WK-6326.</p>Formule :C29H31NO8Couleur et forme :SolidMasse moléculaire :521.56PRN694
CAS :<p>PRN694 is a potent, irreversible ITK/RLK inhibitor with IC50s: 0.3/1.4 nM; offers lasting effector cell suppression.</p>Formule :C28H35F2N5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :543.675-HT7R antagonist 1
<p>5-HT7R antagonist 1 is a G protein-biased antagonist with Ki of 6.5 nM for 5-HT 7R.</p>Formule :C14H18Cl2N4Couleur et forme :SolidMasse moléculaire :313.23B026
CAS :<p>B026: Oral p300/CBP HAT inhibitor, IC50: p300 1.8 nM, CBP 9.5 nM; targets AR+ prostate cancer cells.</p>Formule :C27H23F4N5O4Couleur et forme :SolidMasse moléculaire :557.5NB-216
CAS :<p>NB-216 is a macrocyclic peptidic BACE-1 inhibitor.</p>Formule :C35H45N3O4Couleur et forme :SolidMasse moléculaire :571.75Protease-Activated Receptor-1 antagonist 1
<p>Compound 13 is a PAR-1 antagonist with a 3 nM IC50, useful for thrombosis and heart disease research.</p>Formule :C25H24F2N2O3Couleur et forme :SolidMasse moléculaire :438.47Tubulin inhibitor 14
<p>Tubulin inhibitor 14 blocks NQO2 and microtubule formation, disrupts blood vessels, and may target tumors; IC50 of 1.0 μM.</p>Formule :C15H9F2NOCouleur et forme :SolidMasse moléculaire :257.23MsbA-IN-3
<p>MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).</p>Formule :C24H22Cl2N2O4SCouleur et forme :SolidMasse moléculaire :505.41K252d
CAS :<p>K252d: indolocarbazole alkaloid in Nocardiopsis; inhibits PKC in rat brain and bovine heart phosphodiesterase.</p>Formule :C26H23N3O5Couleur et forme :SolidMasse moléculaire :457.48mPGES-1-IN-1
<p>MPGES-1, potential anti-inflammatory drug target, has IC50 of 0.03 μM with mPGES-1-IN-1.</p>Formule :C21H14N4O2SCouleur et forme :SolidMasse moléculaire :386.43Metoquizine
CAS :<p>Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.</p>Formule :C22H27N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48
