Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.539 produits)
- Apoptose(5.812 produits)
- Cycle cellulaire/point de contrôle(4.460 produits)
- Chromatine/Épigénétique(2.245 produits)
- Signalisation du cytosquelette(1.381 produits)
- Altération de l'ADN/réparation de l'ADN(2.829 produits)
- Endocrinologie/Hormones(3.517 produits)
- Enzyme(3.640 produits)
- GPCR/G-Protéine(8.357 produits)
- Immunologie et Inflammation(3.538 produits)
- Virus de la grippe(296 produits)
- Signalisation JAK/STAT(405 produits)
- Signalisation MAPK(1.203 produits)
- Transporteur membranaire/Canal ionique(2.806 produits)
- Métabolisme(9.456 produits)
- Microbiologie/Virologie(6.998 produits)
- Neuroscience(9.938 produits)
- Autres inhibiteurs(37.853 produits)
- Oxydation-Réduction(40 produits)
- Signalisation PI3K/Akt/mTOR(1.399 produits)
- Protéases/Protéasome(1.600 produits)
- Cellules souche et Dérivés(831 produits)
- Tyrosine Kinase/Adaptateurs(2.016 produits)
- Ubiquitination(1.650 produits)
Affichez 16 plus de sous-catégories
66626 produits trouvés pour "Inhibiteurs"
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LXR antagonist 2
<p>LXR antagonist 2 inhibits adipogenesis, downregulates LXR genes, and reduces lipids in hyperlipidemic mice (LXRβ IC50: 0.36μM, LXRα IC50: 2.25μM).</p>Formule :C34H40N2O5SCouleur et forme :SolidMasse moléculaire :588.76CAII-IN-1
<p>CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.</p>Formule :C19H21FN4SCouleur et forme :SolidMasse moléculaire :356.46Sagopilone
CAS :Sagopilone: synthetic epothilone, inhibits cell division and induces apoptosis, effective in MDR tumors, not P-gp substrate.Formule :C30H41NO6SCouleur et forme :SolidMasse moléculaire :543.71EGFR-IN-17
<p>EGFR-IN-17: potent, selective EGFR inhibitor, IC50 of 0.2 nM, overcomes C797S drug resistance.</p>Formule :C27H31ClN7O3PCouleur et forme :SolidMasse moléculaire :568.01SphK1-IN-2
<p>SphK1-IN-2: SphK1 inhibitor, IC50: 19.81 nM; less effective on SphK2. Induces apoptosis, hinders cancer cell growth.</p>Formule :C27H30BrNO4SCouleur et forme :SolidMasse moléculaire :544.5Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Formule :C14H11N5O4S2Couleur et forme :SolidMasse moléculaire :377.4Antioxidant agent-8
<p>Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation & promotes disaggregation; it's neuroprotective & BBB permeable.</p>Formule :C13H12O5Couleur et forme :SolidMasse moléculaire :248.23KT2-962
CAS :<p>KT2-962 is a TXA2/prostaglandin endoperoxide receptor antagonist.</p>Formule :C23H27ClNNaO5S2Couleur et forme :SolidMasse moléculaire :520.04hCA IX-IN-1
<p>hCA IX-IN-1 inhibits human carbonic anhydrases I, II, IX, and XII with Ki values of 331.4, 28.4, 9.4, 17.8 nM and exhibits anticancer properties.</p>Formule :C19H18N2O3SCouleur et forme :SolidMasse moléculaire :354.42OP-2507
CAS :<p>OP-2507, a prostacyclin agonist, is used potentially for the treatment of hepatic insufficiency and hypertension.</p>Formule :C25H41NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.6SB-612111
CAS :<p>SB-612111: potent ORL-1 antagonist, Ki=0.33 nM; μ-, κ-, δ-receptor Ki=57.6, 160.5, 2109 nM; blocks nociceptin's pain effect.</p>Formule :C24H29Cl2NOCouleur et forme :SolidMasse moléculaire :418.40TBK1/IKKε-IN-1
CAS :<p>TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).</p>Formule :C28H26N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.53Enprostil
CAS :<p>Enprostil: synthetic PGE2 analog, reduces gastric acid, protects mucosa, lowers post-meal gastrin, treats ulcers effectively and safely.</p>Formule :C23H28O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.46Laninamivir trifluoroacetate
CAS :<p>Laninamivir trifluoroacetate, a long-acting antiviral, treats and prevents Influenza A and B via nasal spray.</p>Formule :C15H23F3N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.363BRD7539
CAS :<p>BRD7539B: PfDHODH inhibitor, IC50 0.033μM; selective vs HsDHODH, IC50 >50μM.</p>Formule :C23H22FN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :391.44MRTX849 ethoxypropanoic acid
CAS :<p>MRTX849 is a KRAS G12C ligand and PROTAC linker for creating potent LC-2, degrading KRAS G12C with DC50 of 0.25-0.76 μM.</p>Formule :C37H43ClFN7O5Couleur et forme :SolidMasse moléculaire :720.24GSK2945 hydrochloride
<p>GSK2945 HCl is a specific Rev-erbα antagonist, EC50: 21.5 μM (mouse), 20.8 μM (human), increases cholesterol 7α-hydroxylase.</p>Formule :C20H19Cl3N2O2SCouleur et forme :SolidMasse moléculaire :457.8Teslexivir
CAS :Teslexivir is a topical antiviral agent that is an effective and selective inhibitor of the interaction between two essential viral proteins, E1 and E2.Formule :C35H36BrN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :642.58Fipravirimat
CAS :<p>Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.</p>Formule :C43H67FN2O4SCouleur et forme :SolidMasse moléculaire :727.07TrxR-IN-2
<p>TrxR-IN-2 is a potential thioredoxin reductase (TrxR) inhibitor. TrxR-IN-2 has research value in the chemotherapy of drug-resistant hepatocellular carcinoma.</p>Formule :C22H22N4O4Couleur et forme :SolidMasse moléculaire :406.43JTP-117968
CAS :<p>JTP-117968: Non-steroidal SGRM, glucocorticoid receptor modulator, IC50 = 6.8 nM, offers better inhibitory/activatory balance.</p>Formule :C31H31F3N2O2Couleur et forme :SolidMasse moléculaire :520.59HIV-1 inhibitor-52
CAS :<p>HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.</p>Formule :C46H72FNO5SCouleur et forme :SolidMasse moléculaire :770.13Osanetant HCl
CAS :<p>Osanetant HCl is the (R)-enantiomer; neurokinin-3 receptor antagonist</p>Formule :C35H42Cl3N3O2Couleur et forme :SolidMasse moléculaire :643.09S-1033
CAS :<p>S-1033 is an FP receptor agonist.</p>Formule :C20H33NaO4Couleur et forme :SolidMasse moléculaire :360.4698SMCypI C31
<p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>Formule :C27H30N4O2SCouleur et forme :SolidMasse moléculaire :474.62D18
CAS :<p>D18: Dual agonist for TLR7/8, boosts PD-L1, aids tumor sensitivity to PD-1/PD-L1 inhibitors, and is a cytotoxin for ADC HE-S2.</p>Formule :C21H28N6Couleur et forme :SolidMasse moléculaire :364.49Valopicitabine
CAS :<p>Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic</p>Formule :C15H24N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.37Human carbonic anhydrase II-IN-1
<p>Compound S-13: Potent hCA II inhibitor, Kis 4.4, 9.2, 480.2, 14.7 nM for hCA II, I, IV, IX. Used in glaucoma research.</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5nAChR antagonist 1
CAS :<p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>Formule :C19H22N4O2Couleur et forme :SolidMasse moléculaire :338.4Antimalarial agent 2
<p>Antimalarial agent 2 is an orally active, novel antimalarial agent that exhibits rapid in vitro killing effects.</p>Formule :C27H25N3O5Couleur et forme :SolidMasse moléculaire :471.5NBTIs-IN-5
CAS :<p>NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.</p>Formule :C24H25F3N4O2Couleur et forme :SolidMasse moléculaire :458.48ERK2 IN-1
CAS :<p>ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM.</p>Formule :C36H34FN7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :647.76Ciluprevir
CAS :<p>Ciluprevir is a selective HCV NS3 protease inhibitor, effective against non-genotype-1 HCV; less potent for genotypes 2/3.</p>Formule :C40H50N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :774.93Cap-dependent endonuclease-IN-5
CAS :<p>Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.</p>Formule :C27H21F2N3O4S2Couleur et forme :SolidMasse moléculaire :553.60EP4 receptor antagonist 2
CAS :<p>EP4 receptor antagonist 2 (compound 2-13) is a potent agonist of the EP4 receptor (IC50: 7.8 nM) and has antitumour effects.</p>Formule :C27H29N3O5Couleur et forme :SolidMasse moléculaire :475.54FGFR4-IN-6
<p>FGFR4-IN-6: covalent, reversible FGFR4 blocker, 5.4 nM IC50, good oral bioavailability, reduces Hep3B2.1-7 tumors in mice, low toxicity.</p>Formule :C31H33N7O4Couleur et forme :SolidMasse moléculaire :567.64Vanin-1-IN-3
<p>Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC 50 of 0.038 μM [1].</p>Formule :C17H22F3NO5Couleur et forme :SolidMasse moléculaire :377.36Tribenuron
CAS :<p>Tribenuron, a slow acting sulfonylurea herbicide, controls broadleaf weed.</p>Formule :C14H15N5O6SCouleur et forme :SolidMasse moléculaire :381.36CI 992
CAS :<p>CI 992 is a novel potent inhibitor of primate renin.</p>Formule :C33H52N6O7S2Couleur et forme :SolidMasse moléculaire :708.93BAY-7598
CAS :<p>BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).</p>Formule :C28H31N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.56PptT-IN-1
<p>PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.</p>Formule :C18H29N5O2Couleur et forme :SolidMasse moléculaire :347.46Tubulosine
CAS :<p>Tubulosine is an anticancer agent that inhibits cancer cell growth.</p>Formule :C29H37N3O3Couleur et forme :SolidMasse moléculaire :475.62HIV-1 inhibitor-8
<p>HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.</p>Formule :C25H21N5OSCouleur et forme :SolidMasse moléculaire :439.53TMC353121
CAS :TMC353121 is an effective inhibitor of respiratory syncytial virus fusion (pEC50: 9.9).Formule :C32H42N6O3Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :558.71ODN 2088
CAS :<p>ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.</p>Couleur et forme :SolidAntibacterial agent 78
<p>Antibacterial agent 78 (compound 30) is an antibacterial agent with improved cytotoxicity profile[1].</p>Formule :C16H23N3S2Couleur et forme :SolidMasse moléculaire :321.5JBJ-02-112-05
CAS :<p>JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC 50 of 15 nM for EGFR L858R/T790M [1].</p>Formule :C27H20N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.54Lipoxin A5
CAS :<p>LXA5 is made from EPA by leukocytes, contracts guinea pig lungs like LXA4/LXB4, but doesn't dilate aorta.</p>Formule :C20H30O5Couleur et forme :SolidMasse moléculaire :350.45CP-481715
CAS :<p>CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases.</p>Formule :C26H31FN4O4Couleur et forme :SolidMasse moléculaire :482.55SLN124
<p>SLN124, a GalNAc-siRNA targeting TMPRSS6, may normalize iron balance by restoring ferroregulation.</p>Couleur et forme :SolidR-96544 hydrochloride
CAS :<p>5-HT2 receptor antagonist</p>Formule :C22H29NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.47LY 235959
CAS :<p>LY 235959 is a NMDA receptor antagonist.</p>Formule :C11H20NO5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :277.25Gemilukast
CAS :<p>Gemilukast (ONO-6950) is a cysteinyl leukotriene 1 and 2 receptor inhibitor that inhibits bronchoconstriction and is used in the treatment of asthma.</p>Formule :C36H37F2NO5Degré de pureté :98.27% - 99.5%Couleur et forme :SolidMasse moléculaire :601.683'-Hydroxy Repaglinide
CAS :<p>'3'-Hydroxy Repaglinide, a CYP2C8 metabolite of Repaglinide, treats type II diabetes.</p>Formule :C27H36N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.59Porphobilinogen
CAS :<p>Porphobilinogen act as a phytotoxin, a metabotoxin, and a neurotoxin.</p>Formule :C10H14N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :226.23eIF4A3-IN-4
<p>eIF4A3-IN-4 is a novel inhibitor of eIF4A (IC50: 8.6 μM).</p>Formule :C24H20N2O5Couleur et forme :SolidMasse moléculaire :416.43HPK1-IN-16
CAS :<p>HPK1-IN-16, a potent HPK1 inhibitor, useful for cancer research and treatment.</p>Formule :C28H27FN4OCouleur et forme :SolidMasse moléculaire :454.549-O-Demethyltrigonostemone
CAS :<p>9-O-Demethyltrigonostemone is a natural IDO1 inhibitor, cytotoxic and antiplasmodial agent from the Roots of Strophioblachia fimbricalyx.</p>Formule :C19H20O4Couleur et forme :SolidMasse moléculaire :312.36PARP7-IN-12
CAS :<p>PARP7-IN-12, a potent inhibitor targeting PARP7, exhibits an IC50 of 7.836 nM. This compound is applicable in cancer research.</p>Formule :C23H27ClF3N5O5Couleur et forme :SolidMasse moléculaire :545.94EGFR-IN-45
<p>EGFR-IN-45: Strong EGFR/CDK2 inhibitor (IC50s: 0.4 & 1.6 μM), halts cancer cell cycle pre-G1, prompts apoptosis, also targets Topo I/II.</p>Formule :C28H23N7OCouleur et forme :SolidMasse moléculaire :473.53Valbenazine tosylate
CAS :<p>Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no</p>Formule :C38H54N2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :762.97AL 8810
CAS :<p>AL-8810 is an 11β-fluoro analog of PGF 2α with selective antagonist effects at the PGF 2α receptor (FP receptor) [1].</p>Formule :C24H31FO4Couleur et forme :SolidMasse moléculaire :402.5ODN 21158
CAS :<p>ODN 21158 is a potent, non-cytotoxic inhibitor of G-modified TLR3 and TLR9. ODN 21158 dose-dependently inhibits IFN-α secretion.</p>Couleur et forme :SolidBefiradol hydrochloride
CAS :<p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>Formule :C20H23Cl2F2N3ODegré de pureté :99.1%Couleur et forme :SolidMasse moléculaire :430.32GW311616
CAS :<p>GW-311616 is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).</p>Formule :C19H31N3O4SCouleur et forme :SolidMasse moléculaire :397.53ONL-1204
CAS :<p>ONL-1204 is a small molecule, CD95 antigen inhibitor (Fas inhibitor) being developed by ONL Therapeutics for the treatment of retinal detachment.</p>Formule :C71H100N18O16Couleur et forme :SolidMasse moléculaire :1461.66Seco-Duocarmycin SA
CAS :<p>Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.</p>Formule :C25H24ClN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.93PD 134922
CAS :PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation.Formule :C37H61N5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :719.97CBP/p300-IN-16
<p>CBP/p300-IN-16 (compound 1) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.61 μM) and LK2 H3K27 (IC50: 2.24 μM).</p>Formule :C26H31N3O4Couleur et forme :SolidMasse moléculaire :449.54Hsp90-IN-16
<p>Hsp90-IN-16, a selective HSP90 inhibitor, targets HER2+ cancers with 6 μM IC50 in HCC1954 cells, blocking client proteins and inducing apoptosis.</p>Formule :C30H26FN3O6Couleur et forme :SolidMasse moléculaire :543.54Serlopitant
CAS :<p>Serlopitant is a selective antagonist of Neurokinin-1 (NK-1) receptor.</p>Formule :C29H28F7NO2Couleur et forme :SolidMasse moléculaire :555.53MrgprX2 antagonist-6
<p>MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.</p>Formule :C24H23F3N6O3Couleur et forme :SolidMasse moléculaire :500.47Dopamine D3 receptor ligand-1
<p>Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:</p>Formule :C27H29N5OCouleur et forme :SolidMasse moléculaire :439.55ZLWT-37
<p>ZLWT-37: Oral CDK inhibitor, CDK9 IC50=0.002 µM, CDK2 IC50=0.054 µM; halts HCT116 cells at G2/M, induces apoptosis.</p>Formule :C26H30ClN5OCouleur et forme :SolidMasse moléculaire :464PDE4B/7A-IN-2
CAS :<p>5-HT1A/5-HT7 antagonist; 5-HT1A Ki=8 nM, 5-HT7 Ki=451 nM; PDE4B IC50=80.4 μM, PDE7A IC50=151.3 μM; stronger than escitalopram.</p>Formule :C25H35N3O2Couleur et forme :SolidMasse moléculaire :409.56JTZ-951 HCl
CAS :<p>JTZ-951 is a potent and orally active inhibitor of hypoxia inducible factor prolyl hydroxylase (PHD).</p>Formule :C17H17ClN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.79KY-02327 acetate
<p>KY-02327 acetate inhibits Dvl-CXXC5, stabilizes Wnt/β-catenin signaling, and enhances osteoblast differentiation.</p>Formule :C22H31N3O6Couleur et forme :SolidMasse moléculaire :433.5TIY-7
<p>TIY-7 is a selective, orally active inhibitor of the promyosin receptor kinase (TRK) enzyme. TIY-7 exhibited anti-tumour effects in a mouse xenograft model.</p>Couleur et forme :SolidPF-06263276
CAS :<p>PF-06263276 selectively inhibits pan-JAK with IC50: JAK1 (2.2 nM), JAK2 (23.1 nM), JAK3 (59.9 nM), TYK2 (29.7 nM).</p>Formule :C31H31FN8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :566.63Azotomycin
CAS :Azotomycin is an antagonist of L-glutamine and may be used as an immunosuppressant.Formule :C17H23N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.41TP-030-1
CAS :<p>TP-030-1, RIPK1 inhibitor: K(i) hRIPK1 at 3.9nM, IC50 mRIPK1 at 4.2μM; targets inflammation, neurodegeneration research.</p>Formule :C23H22N4O3Couleur et forme :SolidMasse moléculaire :402.45GNE684
CAS :GNE684 inhibits RIP1; Ki app: 21 nM (human), 189 nM (mouse), 691 nM (rat).Formule :C23H24N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.48L 689065
CAS :L 689065 is a 5-lipoxygenase inhibitor.Formule :C35H33ClN2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :597.17AS2575959
CAS :<p>AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion.</p>Formule :C32H35NaO7Couleur et forme :SolidMasse moléculaire :554.6148CEP-14083
CAS :<p>CEP-14083: potent ALK inhibitor, effective in NPM/ALK T-cell lymphoma, binds ATP site; IC50=11 nmol/L, also inhibits insulin receptor, preclinical efficacy.</p>Formule :C31H30N6O2Couleur et forme :SolidMasse moléculaire :518.61Netupitant metabolite Monohydroxy Netupitant
CAS :Monohydroxy Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.Formule :C30H32F6N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.59Antibacterial agent 66
<p>Compound 6q, a trifluoromethylpyridine oxadiazole, targets Xanthomonas oryzae with EC50 of 7.2 μg/mL.</p>Formule :C17H10ClF6N3O2SCouleur et forme :SolidMasse moléculaire :469.79BMS-741672
CAS :<p>BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.</p>Formule :C25H33F3N6O2Couleur et forme :SolidMasse moléculaire :506.56LY 292728
CAS :<p>LY 292728 is a highly potent antagonist of leukotriene B4 receptor.</p>Formule :C34H29FO9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :600.59CGP 22979
CAS :<p>CGP 22979 is a renal selective vasodilator prodrug.</p>Formule :C16H24N4O4Couleur et forme :SolidMasse moléculaire :336.39STA 2
CAS :<p>STA 2 is an analogue of TXA2, a thromboxane receptor in the colonic epithelium.</p>Formule :C21H34O3SCouleur et forme :SolidMasse moléculaire :366.56Imidocarb dihydrochloride monohydrate
<p>Imidocarb dihydrochloride monohydrate is an effective antiprotozoal agent against the parasite B. bovis (IC50: 87 μg/ml).</p>Formule :C19H24Cl2N6O2Couleur et forme :SolidMasse moléculaire :439.34HDAC-IN-9
<p>HDAC-IN-9, a dual tubulin/HDAC inhibitor, impedes A549 cell invasion/migration and shows strong anti-tumor/angiogenic effects.</p>Formule :C33H38N2O4Couleur et forme :SolidMasse moléculaire :526.67eIF4A3-IN-6
CAS :<p>eIF4A3-IN-6 is a potent eIF4A inhibitor, potentially used for treating eIF4A-related diseases like cancer. (US20170145026A1)</p>Formule :C26H25N3O5Couleur et forme :SolidMasse moléculaire :459.49Zetomipzomib
CAS :<p>KZR-616: Immunoproteasome inhibitor targeting LMP7 (IC50: 39/57 nM) & LMP2 (IC50: 131/179 nM), potential in autoimmune disease research.</p>Formule :C30H42N4O8Couleur et forme :SolidMasse moléculaire :586.68NB-216
CAS :<p>NB-216 is a macrocyclic peptidic BACE-1 inhibitor.</p>Formule :C35H45N3O4Couleur et forme :SolidMasse moléculaire :571.75Mesulergine hydrochloride
CAS :<p>5-HT2A and 2C receptor antagonist</p>Formule :C18H27ClN4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.95L-threo-Sphingosine C-18
CAS :<p>L-threo-Sphingosine C-18 is a protein kinase C inhibitor.</p>Formule :C18H37NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.49Top/HDAC-IN-2
<p>Top/HDAC-IN-2 (45b) is a dual inhibitor of Top and HDAC that induces apoptosis and exhibits significant anti-tumour effects.</p>Formule :C30H32N8O4Couleur et forme :SolidMasse moléculaire :568.63LRRK2-IN-6
<p>LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).</p>Formule :C23H24F2N4O2SCouleur et forme :SolidMasse moléculaire :458.52Antibacterial agent 99
CAS :<p>Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.</p>Formule :C27H27BrN2Couleur et forme :SolidMasse moléculaire :459.42GNE-203
CAS :<p>GNE-203 is a Met inhibitor.</p>Formule :C30H29Cl2F3N8O3Couleur et forme :SolidMasse moléculaire :677.50MDL-27788
CAS :<p>MDL-27788 is a tricyclic inhibitor.</p>Formule :C24H26N2O5SCouleur et forme :SolidMasse moléculaire :454.54VHL Ligand 8
CAS :<p>VHL Ligand 8, a VHL ligand essential for synthesizing ARD-266, acts as a highly potent VHL E3 ligase-based androgen receptor (AR) PROTAC degrader.</p>Formule :C23H29N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.49Lometrexol disodium
CAS :<p>Lometrexol disodium: Inhibits hSHMT1/2 and GARFT, anticancer by blocking purine synthesis, induces apoptosis and cell cycle arrest.</p>Formule :C21H23N5Na2O6Couleur et forme :SolidMasse moléculaire :487.424JAK-2/3-IN-3
<p>JAK-2-/3-IN-3 (ST4j) is a potent JAK2/3 inhibitor for leukemia research, with IC50s: JAK2, 13 nM; JAK3, 14.86 nM; induces apoptosis.</p>Formule :C13H10Cl2N4O2Couleur et forme :SolidMasse moléculaire :325.15HDAC1-IN-5
<p>HDAC1-IN-5 inhibits HDAC1 (IC50=15 nM) & HDAC6 (IC50=20 nM), promotes apoptosis, damages chromatin, and reduces tumor growth in mice.</p>Formule :C20H21N3O2SCouleur et forme :SolidMasse moléculaire :367.46(2R,3S)-Azelaprag
CAS :<p>(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist</p>Formule :C25H29N7O4SDegré de pureté :97.47% - >99.99%Couleur et forme :SoildMasse moléculaire :523.61PI3K-IN-37
CAS :<p>PI3K-IN-37 inhibits PI3K α/β/δ (IC50: 6/8/4 nM) and mTOR (IC50: 4 nM).</p>Formule :C25H26N6O2Couleur et forme :SolidMasse moléculaire :442.51RMG8-8
<p>RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).</p>Formule :C41H78N8O5Couleur et forme :SolidMasse moléculaire :763.11GSK268
<p>GSK268 is a BET inhibitor.</p>Formule :C26H27N5O3Couleur et forme :SolidMasse moléculaire :457.53CVN636
CAS :<p>CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human</p>Formule :C19H20FNO4SCouleur et forme :SolidMasse moléculaire :377.43MNK1/2-IN-6
<p>MNK1/2-IN-6: Strong, selective MNK1/2 inhibitor; IC50s: MNK1 at 2.3 nM, MNK2 at 3.4 nM; triggers dose-dependent apoptosis.</p>Formule :C27H24N6OCouleur et forme :SolidMasse moléculaire :448.52BET-IN-6
CAS :<p>BET-IN-6: Potent BRD2/4 inhibitor and ligand for PROTAC BRD2/BRD4 degrader-1 synthesis.</p>Formule :C22H20N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.472R,4S-Sacubitril
CAS :<p>2R,4S-Sacubitril (Sacubitril Enantiomer) is the impurity of Sacubitril which is a neprilysin inhibitor.</p>Formule :C24H28NO51CaDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.49L-365260 hemihydrate
<p>L-365260 hemihydrate: selective oral CCK-B/gastrin blocker, Ki=1.9/2.0 nM, competes with guinea pig receptors.</p>Formule :C24H24N4O3Couleur et forme :SolidMasse moléculaire :407.47H 218-54
CAS :<p>H 218-54 is a renin inhibitor.</p>Formule :C37H56N2O5SCouleur et forme :SolidMasse moléculaire :640.92TH-6
TH-6, a potent HDAC inhibitor (IC50: HDAC1-0.115, 2-0.135, 3-0.242, 6-0.138, 8-2.120 μM), blocks cell migration, invasion, and has anti-tumor properties.Formule :C22H24FN3O5Couleur et forme :SolidMasse moléculaire :429.44PPI-2458
CAS :<p>PPI-2458, a fumagillin derivative, irreversibly blocks MetAP2, hindering abnormal cell growth and angiogenesis with improved toxicity.</p>Formule :C22H36N2O6Couleur et forme :SolidMasse moléculaire :424.53KFA1982
CAS :<p>KFA1982 is a novel and potent factor Xa inhibitor.</p>Formule :C28H34ClN3O9S2Couleur et forme :SolidMasse moléculaire :656.17β-Glucuronidase/hCAII-IN-2
<p>β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.</p>Formule :C31H23NO8Couleur et forme :SolidMasse moléculaire :537.52Pegcantratinib
CAS :<p>Pegcantratinib is a tropomyosin receptor kinase inhibitor for treatment for inherited CYLD defective skin tumours.</p>Formule :C32H28N4O7Couleur et forme :SolidMasse moléculaire :580.59Trilobolide
CAS :<p>Trilobolide is a natural counterpart of thapsigargin and an activator of cytokine secretion.</p>Formule :C27H38O10Couleur et forme :SolidMasse moléculaire :522.58KRAS G12D inhibitor 1
CAS :<p>KRAS G12D inhibitor 1 (example 243) is an inhibitor of KRAS G12D with an IC 50 of 0.8 nM for KRAS G12D-mediated ERK phosphorylation [1].</p>Formule :C33H32F2N6O2Couleur et forme :SolidMasse moléculaire :582.64PRMT5-IN-21
<p>PRMT5-IN-21 (compound 1) is a potent inhibitor of cyclonucleoside PRMT5.</p>Formule :C18H18F2N6O3Couleur et forme :SolidMasse moléculaire :404.37LAF-153
CAS :<p>LAF-153 is a reversible Methionine Aminopeptidase‑2 (MetAP-2) Inhibitor.</p>Formule :C18H32N2O7Couleur et forme :SolidMasse moléculaire :388.46SB 243213 dihydrochloride
CAS :<p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>Formule :C22H21Cl2F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.33BIIE-0246 HCl
CAS :<p>BIIE-0246: A potent, non-peptide Y2 receptor antagonist; >650-fold more selective than Y1, Y4, Y5.</p>Formule :C49H59Cl2N11O6Couleur et forme :SolidMasse moléculaire :968.97MS8815
CAS :<p>MS8815 is a selective EZH2 PROTAC degrader with IC50 of 8.6 nM, used in triple-negative breast cancer research.</p>Formule :C65H87N9O8SCouleur et forme :SolidMasse moléculaire :1154.51PARP1-IN-12
<p>PARP1-IN-12: potent PARP1 inhibitor, IC50 2.99 nM, triggers cell apoptosis, G2/M arrest, induces DSBs in BRCA-deficient cells.</p>Formule :C43H56FN5O5Couleur et forme :SolidMasse moléculaire :741.93Ep vinyl quinidine
CAS :<p>3-Epiquinine is a Quinidine stereoisomer, used in malaria, antiarrhythmic, inhibits P450db, and blocks K+ channels, IC50: 19.9 μM.</p>Formule :C20H24N2O2Couleur et forme :SolidMasse moléculaire :324.42FXIa-IN-6
CAS :<p>FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.</p>Formule :C31H29ClF2N4O4Couleur et forme :SolidMasse moléculaire :595.04Macitentan (n-butyl analogue)
CAS :Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.Formule :C20H21Br2N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.29MB725
CAS :<p>MB725 is a strong and selective inducer of viability reduction in several cancer cell lines containing the oncogenic p53-Y220C mutation.</p>Formule :C18H21IN4O2SCouleur et forme :SolidMasse moléculaire :484.35BChE-IN-3
<p>BChE-IN-3: Selective, pseudo-irreversible BChE inhibitor (IC50: 56.9 nM); borderline reversible AChE inhibitor.</p>Formule :C26H41N3O2Couleur et forme :SolidMasse moléculaire :427.62Hexedine
CAS :<p>Hexedine is a biochemical.</p>Formule :C22H45N3Couleur et forme :SolidMasse moléculaire :351.61hMAO-B/MB-COMT-IN-1
<p>Dual hMAO-B/MB-COMT inhibitor, IC50: 2.5 μΜ (hMAO-B), 3.84 μΜ (MB-COMT); potential in Parkinson's research.</p>Formule :C16H19NO3Couleur et forme :SolidMasse moléculaire :273.33Anti-inflammatory agent 13
<p>Pentacyclic triterpene, Anti-inflammatory 13 inhibits DAMP/PAMP inflammation models.</p>Formule :C30H48O4Couleur et forme :SolidMasse moléculaire :472.7Kolavenic acid analog
CAS :<p>KAA, an anticancer compound, inhibits centrosome clustering and targets HSET+ yeast and cancer cells.</p>Formule :C25H38O4Couleur et forme :SolidMasse moléculaire :402.57GSK-2878175
CAS :<p>GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formule :C27H23BClFN2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.81ent-8-iso-15(S)-Prostaglandin F2α
CAS :<p>Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid.</p>Formule :C20H34O5Couleur et forme :SolidMasse moléculaire :354.48CDK4/6-IN-10
<p>CDK4/6-IN-10: Oral CDK4 (IC50: 22 nM) & CDK6 (IC50: 10 nM) inhibitor with anti-cancer potential for MM research.</p>Couleur et forme :SolidNTU281
CAS :<p>NTU281 inhibits transglutaminase-2, lowers creatinine in diabetic rats, reduces proteinuria, and fights glomerulosclerosis.</p>Formule :C25H31N2O6SCouleur et forme :SolidMasse moléculaire :487.59Carbonic anhydrase inhibitor 9
<p>Carbonic anhydrase inhibitor 9 targets hCA II and IX with Ki of 56.4 and 56.9 nM respectively; shows antiproliferative activity.</p>Formule :C22H20BrN5O4SCouleur et forme :SolidMasse moléculaire :530.39Antitumor agent-51
<p>Antitumor agent-51 targets osteosarcoma with 21.9 nM IC50, high selectivity, and low toxicity.</p>Formule :C23H25N5O2SCouleur et forme :SolidMasse moléculaire :435.54FAK-IN-4
<p>FAK-IN-4 (Compound 7d) has anticancer activities that can induce cell apoptosis. FAK-IN-4 is potential inhibitor of FAK [1].</p>Formule :C20H22N4OCouleur et forme :SolidMasse moléculaire :334.41AAA-10 formic
<p>AAA-10 formic is an orally active inhibitor of intestinal bacterial bile salt hydrolase (BSH) against B.</p>Formule :C26H43FO7SCouleur et forme :SolidMasse moléculaire :518.68B-3852
CAS :<p>B-3852 is a Bradykinin inhibitor.</p>Formule :C55H74F3N15O11Couleur et forme :SolidMasse moléculaire :1178.27DL-Buthionine-(S,R)-sulfoximine hydrochloride
DL-Buthionine-(S,R)-sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent and specific glutamylcysteine synthetase biosynthesis inhibitorFormule :C8H19ClN2O3SCouleur et forme :SolidMasse moléculaire :258.77Cacospongionolide B
CAS :<p>Cacospongionolide B from Fasciospongia cavernosa inhibits secretory phospholipase A2, curbing inflammation.</p>Formule :C25H36O4Couleur et forme :SolidMasse moléculaire :400.55Nolpitantium besilate
CAS :<p>Nolpitantium besilate is a neurokinin-1 receptor antagonist.</p>Formule :C43H50Cl2N2O5SCouleur et forme :SolidMasse moléculaire :777.84RO5101576
CAS :<p>RO5101576 is a potent antagonist of LTB4 receptor.</p>Formule :C36H38O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :630.75FGFR1 inhibitor-6
<p>FGFR1 inhibitor-6, IC50: 16.31 nM, blocks cell cycle at pro-G1/G2/M and induces apoptosis.</p>Formule :C27H19N5O4S2Couleur et forme :SolidMasse moléculaire :541.6DS88790512
CAS :<p>DS88790512, IC50 at 11 nM, is an effective, selective, oral bioeffective TRPC6 inhibitor.</p>Formule :C22H29N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.48TLR4/NF-κB/MAPK-IN-1
CAS :<p>TLR4/NF-κB/MAPK-IN-1 is a novel antineuroinflammatory agent that functions by inhibiting the TLR4/NF-κB/MAPK pathways.</p>Formule :C19H25BrO6Couleur et forme :SolidMasse moléculaire :429.3K027
<p>K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer's disease.</p>Formule :C15H18Br2N4O2Couleur et forme :SolidMasse moléculaire :446.14IRAK4-IN-15
CAS :<p>IRAK4-IN-15: selective IRAK4 inhibitor, IC50 0.002 μM, good PK, low clearance, synergizes with Acalabrutinib in MyD88/CD79 mutant ABC-DLBCL.</p>Formule :C25H29FN10Couleur et forme :SolidMasse moléculaire :488.56L-97-1
CAS :<p>L-97-1 is an antagonist of the adenosine A1 receptor.</p>Formule :C29H38N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :518.65SPR719
CAS :<p>SPR719 is an inhibitor of gyrase B, has bactericidal activity.</p>Formule :C21H25FN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.46PF-06273340
CAS :<p>PF-06273340 是一种口服具有活力的、具有选择性的外周限制性Trk 泛抑制剂。</p>Formule :C23H22ClN7O3Degré de pureté :98% - 98.00%Couleur et forme :SolidMasse moléculaire :479.92N-methyl Leukotriene C4
CAS :<p>N-methyl LTC4 is a stable synthetic analog of LTC4 and a selective CysLT2 agonist, useful in studying leukotriene pharmacology.</p>Formule :C31H49N3O9SCouleur et forme :SolidMasse moléculaire :639.8Equisetin
CAS :<p>Equisetin: a QSI from Fusarium equiseti, curbs P. aeruginosa virulence, fights Gram-positive bacteria & HIV-1 integrase; not antibacterial to Gram-negative.</p>Formule :C22H31NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.49FGFR4-IN-7
<p>FGFR4-IN-7 is a covalent, reversible FGFR4 inhibitor (IC50: 0.42 μM) that blocks the FGFR4 signaling pathway, thereby inducing apoptosis.</p>Formule :C26H25Cl2N5O3Couleur et forme :SolidMasse moléculaire :526.41Tonapofylline
CAS :<p>Tonapofylline, orally active, selectively blocks A1 adenosine receptor (Ki: 7.4 nM), used in heart failure research.</p>Formule :C22H32N4O4Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :416.51Antitumor agent-74
<p>Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.</p>Formule :C26H23FN6Couleur et forme :SolidMasse moléculaire :438.5PCSK9-IN-16
CAS :<p>PCSK9-IN-16, holds potential for research into hypercholesterolemia and other cardiovascular diseases [1].</p>Formule :C16H20N6O2S3Couleur et forme :SolidMasse moléculaire :424.56DMP 728
CAS :<p>DMP 728 is an antagonist of Glycoprotein IIb-IIIa.</p>Formule :C26H40N8O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :656.71PF-06463922 acetate
CAS :<p>PF-06463922 acetate: ALK/ROS1 inhibitor, brain- penetrable, active vs crizotinib-resistant mutants, in NSCLC trials.</p>Formule :C23H23FN6O4Couleur et forme :SolidMasse moléculaire :466.46GABAA receptor agonist 2
<p>Compound 4c, a potent GABAA agonist with anti-depressive effects in mouse FST/TST, shows promise in depression research.</p>Formule :C22H36O5Couleur et forme :SolidMasse moléculaire :380.52LSD1/2-IN-4
<p>LSD1/2-IN-4, a PCPA derivative, inhibits LSD1 (Ki 0.11 μM) & LSD2 (Ki 130 μM), potentially useful in T-cell leukemia research.</p>Formule :C9H8BrF2NCouleur et forme :SolidMasse moléculaire :248.07Tyk2-IN-3
CAS :<p>Tyk2-IN-3 is an inhibitor of Tyk2 pseudokinase (IC50: 485 nM).</p>Formule :C25H24N6O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.63Chitin synthase inhibitor 1
<p>Potent, selective CHS inhibitor with 0.12 mM IC50; effective against drug-resistant fungi.</p>Formule :C22H20ClN3O3Couleur et forme :SolidMasse moléculaire :409.87Topoisomerase II inhibitor 6
<p>Topoisomerase II inhibitor 6, a potent tryptanthrin derivative, blocks G2 phase in CCRF-CEM cells, induces DNA breaks, and may be used for cancer research.</p>Formule :C19H18N4O2Couleur et forme :SolidMasse moléculaire :334.37PF-06372222
CAS :<p>PF-06372222: a small-molecule that modulates GCGR and antagonizes GLP-1R, affecting insulin and glucagon.</p>Formule :C26H28F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :515.53BAY-3153
CAS :<p>BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) .</p>Formule :C25H29Cl2N3O4Couleur et forme :SolidMasse moléculaire :506.42BGC-638
CAS :<p>BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)–overexpressing tumors.</p>Formule :C32H33N5O9Couleur et forme :SolidMasse moléculaire :631.63DS89002333
<p>DS89002333: oral PRKACA inhibitor with 0.3 nM IC50, effective against FL-HCC with DNAJB1-PRKACA fusion in xenografts.</p>Formule :C22H20ClF2N3O3Couleur et forme :SolidMasse moléculaire :447.86Norbinaltorphimine dihydrochloride
CAS :<p>Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.</p>Formule :C40H45Cl2N3O6Degré de pureté :98.17% - 99.88%Couleur et forme :SolidMasse moléculaire :734.71D4R antagonis-2
<p>Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.</p>Formule :C21H23ClF2N2O2Couleur et forme :SolidMasse moléculaire :408.87MraY-IN-2
<p>MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.</p>Formule :C16H23N3O9Couleur et forme :SolidMasse moléculaire :401.3712(S)-HETE
CAS :<p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47PF1070A
CAS :<p>PF1070A is a natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothionein</p>Formule :C31H44N4O6Couleur et forme :SolidMasse moléculaire :568.7DNA gyrase B-IN-1
<p>DNA gyrase B-IN-1, a potent inhibitor of P. aeruginosa DNA gyrase B, has IC50 of 2.2 μM with high affinity and stability.</p>Formule :C23H18ClF3N6O4SCouleur et forme :SolidMasse moléculaire :566.94CB30865
CAS :CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.Formule :C26H22BrN5O2Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :516.39KPH2f
CAS :<p>KPH2f: dual URAT1/GLUT9 inhibitor, orally active, IC50: 0.24μM (URAT1), 9.37μM (GLUT9), minimal OAT1/ABCG2 impact.</p>Formule :C24H16N3NaO2SCouleur et forme :SolidMasse moléculaire :433.46Henagliflozin
CAS :<p>Henagliflozin (SHR3824): an oral, selective SGLT2 inhibitor, weak on SGLT1.</p>Formule :C22H24ClFO7Couleur et forme :SolidMasse moléculaire :454.87Anti-inflammatory agent 12
<p>Pentacyclic triterpene, anti-inflammatory agent 12, inhibits LPS inflammation (IC50: 2.22 μM). May benefit inflammatory disease studies.</p>Formule :C30H50O4Couleur et forme :SolidMasse moléculaire :474.72CXCR2 antagonist 7
<p>CXCR2 antagonist 7 is a powerful blocker with IC50s: 0.044 μM for binding, 0.66 μM for calcium mobilization.</p>Formule :C14H14F2N6OSCouleur et forme :SolidMasse moléculaire :352.36LY3325656
CAS :<p>LY3325656, a GPR142 agonist with anti-diabetic properties, progresses to phase 1 trials for Type 2 diabetes.</p>Formule :C21H23F3N6O2Couleur et forme :SolidMasse moléculaire :448.44Bleomycin Free Base
CAS :<p>Bleomycin Free Base, a glycopeptide antibiotic, halts DNA function and treats solid tumors.</p>Formule :C55H84N17O21S3Couleur et forme :SolidMasse moléculaire :1415.55Niravoline
CAS :<p>Niravoline is a kappa-opioid agonist.</p>Formule :C22H25N3O3Couleur et forme :SolidMasse moléculaire :379.45AX15910
<p>AX15910 is a potent inhibitor of BRD4 and ERK5.</p>Formule :C32H38N6O3Couleur et forme :SolidMasse moléculaire :554.7MRS2179 tetrasodium hydrate
<p>MRS2179 blocks turkey P2Y1 receptor (Kb 102 nM, pA2 6.99), affects platelet aggregation, and has varying IC50s on P2 receptors.</p>Formule :C11H15N5Na4O10P2Couleur et forme :SolidMasse moléculaire :576.21NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Formule :C14H9IN2O3SCouleur et forme :SolidMasse moléculaire :412.2ORP-101
CAS :<p>ORP-101: large, stable molecule with partial μ agonist, full κ antagonist properties.</p>Formule :C60H84N2O8Couleur et forme :SolidMasse moléculaire :961.32Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Formule :C31H44N2O6SCouleur et forme :SolidMasse moléculaire :572.76THR-β agonist 4
CAS :<p>THR-β agonist 4 is a potent agonist of THR-β.</p>Formule :C16H11Cl2F2N5O6SCouleur et forme :SolidMasse moléculaire :510.26N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
<p>N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].</p>Formule :C11H9FN4OCouleur et forme :SolidMasse moléculaire :232.21EED ligand 1
<p>EED ligand 1: potent PRC2 inhibitor targeting EED subunit.</p>Formule :C19H19FN8OCouleur et forme :SolidMasse moléculaire :394.41MRS4458
CAS :<p>MRS4458 is an effective inhibitor of the P2Y14 Receptor.</p>Formule :C24H20F3N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :515.51
