Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.524 produits)
- Apoptose(5.793 produits)
- Cycle cellulaire/point de contrôle(4.452 produits)
- Chromatine/Épigénétique(2.242 produits)
- Signalisation du cytosquelette(1.382 produits)
- Altération de l'ADN/réparation de l'ADN(2.826 produits)
- Endocrinologie/Hormones(3.507 produits)
- Enzyme(3.640 produits)
- GPCR/G-Protéine(8.333 produits)
- Immunologie et Inflammation(3.527 produits)
- Virus de la grippe(296 produits)
- Signalisation JAK/STAT(404 produits)
- Signalisation MAPK(1.203 produits)
- Transporteur membranaire/Canal ionique(2.792 produits)
- Métabolisme(9.449 produits)
- Microbiologie/Virologie(6.981 produits)
- Neuroscience(9.926 produits)
- Autres inhibiteurs(37.921 produits)
- Oxydation-Réduction(41 produits)
- Signalisation PI3K/Akt/mTOR(1.400 produits)
- Protéases/Protéasome(1.597 produits)
- Cellules souche et Dérivés(830 produits)
- Tyrosine Kinase/Adaptateurs(2.015 produits)
- Ubiquitination(1.650 produits)
Affichez 16 plus de sous-catégories
66639 produits trouvés pour "Inhibiteurs"
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Antiviral agent 6
<p>Antiviral agent 6 showed excellent anti-TSWV effects in vivo (EC50: 188 mg/L).</p>Formule :C23H27BrN2O3S2Couleur et forme :SolidMasse moléculaire :523.51L 365209
CAS :<p>L 365209 is an oxytocin antagonist.</p>Formule :C40H50N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :738.88Oral antiplatelet agent 1
CAS :<p>Oral antiplatelet agent 1 is a potent antiplatelet agent with an IC50 of 2.94 μM in vitro.</p>Formule :C23H24N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.53Topoisomerase I/II inhibitor 3
<p>Topoisomerase I/II inhibitor 3 suppresses cell growth and induces apoptosis in liver cancer by blocking PI3K/Akt/mTOR.</p>Formule :C24H24N2O4Couleur et forme :SolidMasse moléculaire :404.46DG013A
CAS :<p>DG013A inhibits ERAP1 & ERAP2 (IC50: 33 nM & 11 nM) to research autoimmune diseases & cancer.</p>Formule :C27H37N4O4PCouleur et forme :SolidMasse moléculaire :512.58Musettamycin
CAS :<p>Musettamycin triggers erythroid differentiation in blood cells, acts like anthracycline antibiotics, but only inhibits gram-positive bacteria.</p>Formule :C36H45NO14Couleur et forme :SolidMasse moléculaire :715.745-Ph-IAA-AM
<p>5-Ph-IAA-AM, eggshell-permeable analog of 5-Ph-IAA, boosts protein degradation in embryos, useful for studying proteins in C. elegans.</p>Formule :C19H17NO4Couleur et forme :SolidMasse moléculaire :323.342-Methylsorbinol
CAS :<p>2-Methylsorbinol is a bioactive chemical.</p>Formule :C12H11FN2O3Couleur et forme :SolidMasse moléculaire :250.23BRD-K25923209
CAS :<p>BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.</p>Formule :C29H36N4O3Couleur et forme :SolidMasse moléculaire :488.62APN/AKT-IN-1
<p>APN/AKT-IN-1, a dual APN (IC50=0.21μM) & AKT (IC50=0.27μM) inhibitor, hinders GSK3β phosphorylation.</p>Formule :C18H27N7O3Couleur et forme :SolidMasse moléculaire :389.45LY 190388
CAS :<p>LY 190388 is a penicillamine-containing enkephalin analog used as an mu receptor agonist with analgesia activity.</p>Formule :C30H41N5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :615.74Teslexivir hydrochloride
CAS :<p>Teslexivir (BTA074) HCl inhibits HPV 6/11 by blocking E1-E2 protein interaction, vital for DNA replication. Used in condyloma research.</p>Formule :C35H37BrClN3O4Couleur et forme :SolidMasse moléculaire :679.04Dehatrine
CAS :<p>Dehatrine: alkaloid from Beilschmiedia madang, inhibits Plasmodium falciparum K1 growth.</p>Formule :C37H38N2O6Couleur et forme :SolidMasse moléculaire :606.71Antioxidant agent-3
<p>Antioxidant agent-3 shows strong DPPH and ABTS+ radical scavenging (IC50: 26.58, 30.31 μM). Boosts ROS, SOD, GSH; lowers LDH in H2O2-exposed HepG2 cells.</p>Formule :C18H14O8Couleur et forme :SolidMasse moléculaire :358.3Fostriecin (free base)
CAS :<p>Fostriecin inhibits PP2A/PP4 (IC50s = 3.2/3 nM), weakly affects topoisomerase II/PP1 (IC50s = 40/131 μM), doesn't inhibit PP2B, and may modify epigenetics.</p>Formule :C19H27O9PCouleur et forme :SolidMasse moléculaire :430.39T-2513 hydrochloride
CAS :<p>T-2513 hydrochloride: selective topoisomerase I inhibitor, binds DNA complex, halts DNA/RNA synthesis, causes cell death.</p>Formule :C25H28ClN3O5Couleur et forme :SolidMasse moléculaire :485.96O-GlcNAcase-IN-1
<p>O-GlcNAcase-IN-1 is a potent and novel inhibitor of O-GlcNAcase(OGA) with an IC 50 value of 46 nM.</p>Formule :C15H22N6Couleur et forme :SolidMasse moléculaire :286.38β-Secretase Inhibitor III
<p>β-Secretase Inhibitor III is a highly selective inhibitor of BACE1 with a Ki value of 0.13 nM.</p>Formule :C20H20F2N4O3SCouleur et forme :SolidMasse moléculaire :434.46HDAC-IN-27
<p>HDAC-IN-27 is a potent and orally active inhibitor of HDAC Class I (0.43 nM - 3.01 nM for HDAC1-3).</p>Formule :C20H22N4O2Couleur et forme :SolidMasse moléculaire :350.41Tasidotin hydrochloride
CAS :<p>Tasidotin hydrochloride, a dolastatin 15 analog, inhibits microtubule assembly and dynamics.</p>Formule :C32H59ClN6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :643.30Nonsteroidal aromatase inhibitor 1
<p>Compound 13h, a nonsteroidal aromatase inhibitor, has a potent IC50 of 0.09 nM against CYP19A1, showing promise for breast cancer research.</p>Formule :C22H16N4O2Couleur et forme :SolidMasse moléculaire :368.39Anticancer agent 64
CAS :<p>Anticancer agent 64 (5m) induces apoptosis, has IC50 2.4μM in CCRF-CEM, activates caspases, cleaves PARP, affects mitochondria.</p>Formule :C31H46N2O2SCouleur et forme :SolidMasse moléculaire :510.77MAP855
CAS :<p>MAP855: potent, selective, oral MEK1/2 inhibitor; IC50=3 nM, pERKEC50=5 nM; effective on wild-type/mutant MEK1/2.</p>Formule :C28H23ClF2N6O3Couleur et forme :SolidMasse moléculaire :564.97CYP2C9/CYP2C19-IN-1
<p>CYP2C9/CYP2C19-IN-1 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.</p>Formule :C27H28N2O6SCouleur et forme :SolidMasse moléculaire :508.59Tovinontrine
CAS :<p>Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment.</p>Formule :C21H26N6O2Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :394.47BMS-741672
CAS :<p>BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.</p>Formule :C25H33F3N6O2Couleur et forme :SolidMasse moléculaire :506.56iMDK quarterhydrate
<p>iMDK quarterhydrate, PI3K inhibitor, blocks MDK growth; suppresses NSCLC safely with MEK inhibitor.</p>Formule :C21H15FN2O3SCouleur et forme :SolidMasse moléculaire :380.91VEGFR-2-IN-17
<p>VEGFR-2-IN-17 (15a) is a potent VEGFR-2 inhibitor with an IC50 of 67.25 nM, showing significant antitumor effects.</p>Formule :C21H14ClN3O2Couleur et forme :SolidMasse moléculaire :375.81ONO-AE1-259 lysine
CAS :<p>ONO-AE1-259 is a highly selective agonist of prostaglandin e2 receptor (ep2)</p>Formule :C28H49ClN2O6Couleur et forme :SolidMasse moléculaire :545.15AS2575959
CAS :<p>AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion.</p>Formule :C32H35NaO7Couleur et forme :SolidMasse moléculaire :554.6148Terpendole E
CAS :<p>Terpendole E is an atypical L5 site inhibitor.</p>Formule :C28H39NO3Couleur et forme :SolidMasse moléculaire :437.61TIY-7
<p>TIY-7 is a selective, orally active inhibitor of the promyosin receptor kinase (TRK) enzyme. TIY-7 exhibited anti-tumour effects in a mouse xenograft model.</p>Couleur et forme :SolidNPEC-caged-(S)-3,4-DCPG
CAS :<p>mGlu8a agonist</p>Formule :C19H16N2O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.34Anticancer agent 78
<p>Anticancer agent 78: anti-aromatase (IC50=0.9 μM), cytotoxic, potential in breast cancer research.</p>Formule :C19H14BrNO4Couleur et forme :SolidMasse moléculaire :400.22CP-199330
CAS :<p>CP-199330: non-toxic alternative to Zafirlukast & Pranlukast, blocks cysteyl LT1 receptors.</p>Formule :C28H24ClF3N2O6SCouleur et forme :SolidMasse moléculaire :609.01LY 235959
CAS :<p>LY 235959 is a NMDA receptor antagonist.</p>Formule :C11H20NO5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :277.25GP-1681
CAS :<p>GP-1681, a G-protein coupled receptor (GPCR) agonist, is used potentially for the treatment of influenza infection.</p>Formule :C24H30NaO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.48EGFR-IN-47
<p>EGFR-IN-47: strong oral EGFRL858R/T790M/C797S blocker, induces cell death; promising for NSCLC research. IC50: 0.01 μM.</p>Formule :C29H35N7Couleur et forme :SolidMasse moléculaire :481.64TP-030-1
CAS :<p>TP-030-1, RIPK1 inhibitor: K(i) hRIPK1 at 3.9nM, IC50 mRIPK1 at 4.2μM; targets inflammation, neurodegeneration research.</p>Formule :C23H22N4O3Couleur et forme :SolidMasse moléculaire :402.45sEH inhibitor-2
<p>SEH inhibitor-2 is an orally active sEH blocker (IC50=0.9 nM) with predicted 71.2-88.4% absorption, potentially aiding cardiovascular health.</p>Formule :C23H18N4O3Couleur et forme :SolidMasse moléculaire :398.41CXCR4 antagonist 3
<p>CXCR4 antagonist 3, aka compound 12a, has 11 nM IC50, shares TIQ15 traits, and is promising in HIV research.</p>Formule :C22H31N5Couleur et forme :SolidMasse moléculaire :365.52GNE-431
CAS :<p>GNE-431: potent, selective noncovalent Btk inhibitor, IC50=3.2 nM; effective against C481R, T474I, T474M mutants, may counter ibrutinib resistance.</p>Formule :C30H32N10O2Couleur et forme :SolidMasse moléculaire :564.64DNDI-8219
CAS :<p>DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.</p>Formule :C13H10F3N3O5Couleur et forme :SolidMasse moléculaire :345.23Flusoxolol
CAS :<p>Flusoxolol is a beta-adrenoceptor partial agonist.</p>Formule :C22H30FNO4Couleur et forme :SolidMasse moléculaire :391.48J-104871
CAS :<p>J-104871 (UNII-6137X5QNJF) is an FTase inhibitor that inhibits tumor growth in nude mice transplanted with activated H-ras-transformed NIH3T3 cells.</p>Formule :C38H32N2O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :708.67MCB-3681
CAS :<p>MCB-3681, active against gram-positive bacterium, is the antibacterial Oxaquin's active substance.</p>Formule :C31H32F2N4O8Couleur et forme :SolidMasse moléculaire :626.6CDK9-IN-13
<p>CDK9-IN-13 is a potent and selective CDK inhibitor (IC50<3 nM). CDK9-IN-13 has a very short half-life in rodents.</p>Formule :C27H35N5O2Couleur et forme :SolidMasse moléculaire :461.6TAM&Met-IN-1
CAS :<p>TAM&Met-IN-1 inhibits AXL, MER, TYRO3 with IC50s 6.1, 13.2, 21.6 nM, respectively, for cancer research.</p>Formule :C29H27F2N7O5Couleur et forme :SolidMasse moléculaire :591.57Terguride
CAS :<p>Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.</p>Formule :C20H28N4OCouleur et forme :SolidMasse moléculaire :340.46Carbonic anhydrase inhibitor 8
<p>R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5PARP-1/HDAC-IN-1
CAS :<p>PARP-1/HDAC-IN-1 is a PARP-1 and HDAC6 inhibitor with anticancer, antimigratory, and antiangiogenic activities and is used in tumor research.</p>Formule :C22H18N4O4Degré de pureté :95.94%Couleur et forme :SolidMasse moléculaire :402.4GSK-3036656 free base
CAS :<p>GSK656 (GSK3036656) inhibits Mtb LeuRS with IC50 of 0.20 μM, promising for tuberculosis treatment.</p>Formule :C10H13BClNO4Couleur et forme :SolidMasse moléculaire :257.48EGFR/HER2-IN-7
<p>EGFR/HER2-IN-7: Potent, selective dual inhibitor for MCF-7 cancer; IC50: EGFR 0.18μM, HER2 0.146μM, DHFR 0.907μM.</p>Formule :C19H21N3O2SCouleur et forme :SolidMasse moléculaire :355.45Amrubicin HCl
CAS :<p>Amrubicin (SM-5887), an anthracycline, treats lung cancer by inhibiting DNA replication and topoisomerase II, with less cardiac toxicity.</p>Formule :C25H25NO9Couleur et forme :SolidMasse moléculaire :483.47Barixibat
CAS :<p>Barixibat is a bile acid transport inhibitor.</p>Formule :C42H55N5O8Couleur et forme :SolidMasse moléculaire :757.91Vibegron
CAS :<p>Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).</p>Formule :C26H28N4O3Couleur et forme :SolidMasse moléculaire :444.53Dictyostatin
CAS :<p>Dictyostatin: potent microtubule stabilizer & anticancer agent with antiproliferative effects; researched for tauopathies.</p>Formule :C32H52O6Couleur et forme :SolidMasse moléculaire :532.75LT-850-166
<p>LT-850-166 is a potent inhibitor of FLT3 and has shown efficacy in overcoming a wide range of FLT3 mutations.</p>Formule :C30H29Cl2N7OCouleur et forme :SolidMasse moléculaire :574.5Antibacterial agent 110
<p>Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).</p>Formule :C22H21N5O4SCouleur et forme :SolidMasse moléculaire :451.5Anti-inflammatory agent 19
<p>Anti-inflammatory agent 19: NO inhibitor (IC50: 36μM), blocks HMGB1, for late-stage inflammation, relevant for COVID-19, sepsis.</p>Formule :C30H50O7Couleur et forme :SolidMasse moléculaire :522.71WAY-855
CAS :<p>WAY-855 is an EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake.</p>Formule :C9H11NO4Couleur et forme :SolidMasse moléculaire :197.19M-89 MLL inhibitor
CAS :<p>M-89, a potent Menin-MLL blocker: Kd 1.4 nM, IC50 25 nM for MV4;11 cells, 55 nM for MOLM-13, >100x selective over HL-60.</p>Formule :C37H47N5O4SCouleur et forme :SolidMasse moléculaire :657.87PDE-I2
CAS :<p>PDE-I2 is a parasite schizogony inhibitor.</p>Formule :C25H23N5O8Couleur et forme :SolidMasse moléculaire :521.48SSTR5 antagonist 2 hydrochloride
<p>SSTR5 antagonist 2 hydrochloride: potent, oral SSTR5 blocker with potential in type 2 diabetes research.</p>Formule :C32H36ClFN2O5Couleur et forme :SolidMasse moléculaire :583.09YW3-56
CAS :<p>YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.</p>Formule :C27H32ClN5O2Couleur et forme :SolidMasse moléculaire :494.03JAK-IN-23
<p>"JAK-IN-23: oral dual JAK/STAT & NF-κB inhibitor; JAK1 (IC50: 8.9 nM), JAK2 (15 nM), JAK3 (46.2 nM); for IBD research."</p>Formule :C23H22Cl2N4OCouleur et forme :SolidMasse moléculaire :441.35Cas9-IN-1
<p>Cas9-IN-1 is a potent inhibitor of Cas9 with an IC50 value of 7.02 μM. Cas9-IN-1 acts by binding apo-Cas9 and blocking the formation of the Cas9:gRNA complex.</p>Formule :C17H11Cl2F3N2O3SCouleur et forme :SolidMasse moléculaire :451.25Chitin synthase inhibitor 5
<p>Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.</p>Formule :C23H22BrN3O5Couleur et forme :SolidMasse moléculaire :500.34Triciferol
CAS :<p>Triciferol is a VDR agonist and HDAC antagonist with 1,25D-like potency, affecting gene targets and tubulin, and shows anti-cancer effects in vitro. IC50=87nM.</p>Formule :C26H39NO4Couleur et forme :SolidMasse moléculaire :429.591AEP-IN-1
<p>APE-IN-1, a potent AEP inhibitor (IC50: 89 nM), aids Alzheimer's diagnosis and drug research.</p>Formule :C18H27N3O3Couleur et forme :SolidMasse moléculaire :333.43Demethoxyviridin
CAS :<p>Demethoxyviridin inhibits mammalian Ptdlns 3-kinase (p110) and is antifungal.</p>Formule :C19H14O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.31KRAS G12C inhibitor 33
CAS :<p>KRAS G12C inhibitor 33 is a KRAS G12C inhibitor that can be used to study cancer.</p>Formule :C30H33N7O3Couleur et forme :SolidMasse moléculaire :539.63AChE/GSK-3β-IN-1
CAS :<p>AChE/GSK-3β-IN-1 is a potent dual AChE/GSK-3β inhibitor that crosses the blood-brain barrier and acts on hAChE (IC50: 1.2 nM), hBChE (IC50: 149.8 nM) and hGSK-</p>Formule :C31H35N7O3SCouleur et forme :SolidMasse moléculaire :585.72ART615
<p>ART615 is a related isomer of ART558. ART615 inhibits Polθ by <10% at 12 μM and is able to act as a control for ART558 (IC50:7.9 nM).</p>Formule :C21H21F3N4O2Couleur et forme :SolidMasse moléculaire :418.41MsbA-IN-2
<p>MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).</p>Formule :C23H19Cl2NO3Couleur et forme :SolidMasse moléculaire :428.31Zanapezil fumarate
CAS :<p>Zanapezil is an acetylcholinesterase (AChE) inhibitor. Zanapezil increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.</p>Formule :C29H36N2O5Couleur et forme :SolidMasse moléculaire :492.61Multi-kinase-IN-1
CAS :<p>Multi-kinase-IN-1, a powerful kinase inhibitor, exhibits antitumor properties by inducing cell apoptosis.</p>Formule :C35H36F2N6O6SCouleur et forme :SolidMasse moléculaire :706.76hDHODH-IN-10
<p>hDHODH-IN-10: selective oral inhibitor of hDHODH (IC50: 10.9 nM); blocks cancer cell growth, aids cancer research.</p>Formule :C21H15ClF4N2O4Couleur et forme :SolidMasse moléculaire :470.8Pamiparib maleate
CAS :<p>Pamiparib (BGB-290) is a selective PARP inhibitor that blocks DNA repair and promotes apoptosis.</p>Formule :C44H42F2N8O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :944.859Antitumor agent-76
CAS :<p>Antitumor agent-76 is a water-soluble, orally active, rapid-release prodrug of Triptolide that exhibits anticancer effects.</p>Formule :C28H36ClNO10Couleur et forme :SolidMasse moléculaire :582.04FY-56
<p>FY-56: potent, selective LSD1/KDM1A inhibitor (IC50=42nM); differentiates MOLM-13/MV4-11 cells; promising for AML research.</p>Formule :C23H19FN2O3Couleur et forme :SolidMasse moléculaire :390.41G092
<p>G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter protein. G092 has potential for antibacterial drug research.</p>Formule :C23H20Cl2N2O3Couleur et forme :SolidMasse moléculaire :443.32Minnelide
CAS :<p>Minnelide is a prodrug of triptolide,and shows potent antitumor activity in a number of tumor types.</p>Formule :C21H25Na2O10PDegré de pureté :98.49% - 99.59%Couleur et forme :SolidMasse moléculaire :514.37Tezampanel hydrate
CAS :<p>Tezampanel is used for the treatment of migraine, neuropathic pain.</p>Formule :C13H23N5O3Couleur et forme :SolidMasse moléculaire :297.35Samuraciclib
CAS :<p>Samuraciclib (CT7001) is an oral CDK7 inhibitor with 41 nM IC50, notable for its high selectivity and potency against breast cancer cells.</p>Formule :C22H30N6OCouleur et forme :SolidMasse moléculaire :394.51PD-1-IN-17
CAS :<p>PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.</p>Formule :C13H22N6O7Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :374.35SLC4011540
<p>SLC4011540 is a potent and selective SphK1/2 dual inhibitor with Ki value of 120 nM and 90 nM respectively.</p>Formule :C24H23ClF3N7OSCouleur et forme :SolidMasse moléculaire :550BMS-824
CAS :<p>BMS-824: potent HCV NS5A inhibitor, IC50 ~5 nM, therapeutic index >10,000, specific to HCV.</p>Formule :C27H25F3N4O5Couleur et forme :SolidMasse moléculaire :542.51RET-IN-14
CAS :<p>RET-IN-14 inhibits RET (IC50: <0.51-9.3 nM) & BTK (C481S) (IC50: 9.2-15 nM), promising for tumor research.</p>Formule :C24H23FN8O4Couleur et forme :SolidMasse moléculaire :506.49MT-134
<p>MT-134 is a SkMII -specific inhibitor and has excellent exposure in muscles.</p>Formule :C19H16N4O3Couleur et forme :SolidMasse moléculaire :348.36SK&F 108361
CAS :<p>SK&F 108361 is a symmetric diol that binds HIV-1 protease symmetrically.</p>Formule :C24H48N6O6Couleur et forme :SolidMasse moléculaire :516.67Oiligodendrocyte differentiation promoter 1
CAS :<p>Oiligodendrocyte differentiation promoter 1 is a promoter of oiligodendrocyte differentiation .</p>Formule :C25H25Cl2NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.38CGC 11144
CAS :<p>CGC 11144 is a Polyamine analogue inhibit tumor growth in vitro and in vivo.</p>Formule :C40H100Cl10N10Couleur et forme :SolidMasse moléculaire :1075.82PF-07202954
CAS :<p>PF-07202954, a weakly basic diacylglycerol O-acyltransferase 2 (DGAT2) inhibitor, exhibits an inhibition concentration half-maximum (IC50) of 10 nM against</p>Formule :C22H23FN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.45WW437
<p>WW437 is a histone deacetylase (HDAC) inhibitor that exhibits potent anti-breast cancer activity both in vitro and in vivo.</p>Formule :C23H27N5O4Couleur et forme :SolidMasse moléculaire :437.49IRE1α kinase-IN-4
CAS :<p>IRE1α kinase-IN-4 (compound 6) is a potent inhibitor of IRE1α, exhibiting a Ki value of 140 nM. It acts as an ATP-competitive ligand for IRE1α [1].</p>Formule :C29H31N7O2Couleur et forme :SolidMasse moléculaire :509.6AKR1C3-IN-7
<p>AKR1C3-IN-7 (Compound 13) is an effective and selective AKR1C3 inhibitor (IC50=0.19 μM). AKR1C3-IN-7 has antitumor activity.</p>Formule :C24H20N2O4Couleur et forme :SolidMasse moléculaire :400.43Mu opioid receptor antagonist 3
<p>Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.</p>Formule :C25H28N2O4SCouleur et forme :SolidMasse moléculaire :452.57VEGFR-2-IN-14
<p>VEGFR-2-IN-14 (Compound 5) is a potent inhibitor of VEGFR-2, which inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.</p>Formule :C24H23N3O3SCouleur et forme :SolidMasse moléculaire :433.52MRS2179 tetrasodium hydrate
<p>MRS2179 blocks turkey P2Y1 receptor (Kb 102 nM, pA2 6.99), affects platelet aggregation, and has varying IC50s on P2 receptors.</p>Formule :C11H15N5Na4O10P2Couleur et forme :SolidMasse moléculaire :576.21ORIC-101
CAS :<p>ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity.</p>Formule :C34H47NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.74Antileishmanial agent-4
<p>Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].</p>Formule :C17H18N4O4Couleur et forme :SolidMasse moléculaire :342.35LASSBio-1632
<p>LASSBio-1632: Novel anti-asthmatic, blocks PDE4A/D, reduces AHR & lung TNF-α, crosses BBB.</p>Formule :C18H20N2O6SCouleur et forme :SolidMasse moléculaire :392.43AMXI-5001 hydrochloride
<p>AMXI-5001 hydrochloride, an oral inhibitor of PARP1/2 and microtubules, shows greater potency and selective anti-cancer effects.</p>Formule :C25H21ClFN5O3Couleur et forme :SolidMasse moléculaire :493.92Axl-IN-3
<p>Axl-IN-3 is a selective, potent and orally active inhibitor of AXL kinase (IC50: 41.5 nM) and has a low inhibitory effect on other kinases.</p>Formule :C24H25ClN6O2Couleur et forme :SolidMasse moléculaire :464.95BGC-638
CAS :<p>BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)–overexpressing tumors.</p>Formule :C32H33N5O9Couleur et forme :SolidMasse moléculaire :631.63Mimocine
CAS :<p>Mimosine, a plant amino acid, is known to act as a normoxic inducer of hypoxia-inducible factor (HIF).</p>Formule :C15H14N2O5Couleur et forme :SolidMasse moléculaire :302.28Saphenamycin
CAS :<p>Saphenamycin is an antibiotic from a strain of Streptomyces.</p>Formule :C23H18N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.40CXCR4 modulator-1
CAS :<p>CXCR4 modulator-1 (ZINC72372983) is potent (EC50=100nM) with uses in anti-inflammatory, anticancer, and anti-HIV research.</p>Formule :C23H27N5O2Couleur et forme :SolidMasse moléculaire :405.49N-methyl Leukotriene C4
CAS :<p>N-methyl LTC4 is a stable synthetic analog of LTC4 and a selective CysLT2 agonist, useful in studying leukotriene pharmacology.</p>Formule :C31H49N3O9SCouleur et forme :SolidMasse moléculaire :639.8FTI-2153 TFA
<p>FTI-2153 TFA inhibits farnesyltransferase with high selectivity (IC50: 1.4 nM), over 3000x more than Rap1A processing.</p>Formule :C27H31F3N4O5SCouleur et forme :SolidMasse moléculaire :580.62ARG1-IN-1
CAS :<p>ARG1-IN-1 is a human arginase 1 inhibitor with an IC 50 of 29 nM.</p>Formule :C11H21BN2O4Couleur et forme :SolidMasse moléculaire :256.11BAY-3153
CAS :<p>BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) .</p>Formule :C25H29Cl2N3O4Couleur et forme :SolidMasse moléculaire :506.42Unoprostone isopropyl
CAS :<p>Unoprostone isopropyl, a prostanoid and synthetic docosanoid, is approved for the treatment of ocular hypertension and open-angle glaucoma.</p>Formule :C25H44O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.61LpxA-IN-1
CAS :<p>LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa</p>Formule :C21H11D7F3N5O3Couleur et forme :SolidMasse moléculaire :452.44Orvepitant
CAS :<p>Orvepitant is a potent and selective NK1 antagonist, which may be potentially useful for patients with major depressive disorder (MDD), anxiety and insomnia.</p>Formule :C31H35F7N4O2Couleur et forme :SolidMasse moléculaire :628.62(R)-FL118
CAS :<p>FL118 inhibits human survivinion expression and activates tumor suppressor p53 as a MOA in p53 wild-type cancer cells.</p>Formule :C21H16N2O6Couleur et forme :SolidMasse moléculaire :392.36Sacibertinib
CAS :<p>Sacibertinib inhibits Trk, targeting EGFR-TK (EC50 110 nM) & HER2 (EC50 244 nM), with anticancer properties.</p>Formule :C32H31ClN6O4Couleur et forme :SolidMasse moléculaire :599.08J-104118
CAS :<p>J-104118 potentially inhibits squalene synthase.</p>Formule :C28H26Cl2FNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :546.41BACE-1 inhibitor 2
CAS :<p>BACE-1 Inhibitor 2 is a potent, CNS-permeable inhibitor of BACE-1, exhibiting an IC50 value of 1.5 nM in enzymatic assays [1].</p>Formule :C21H21F4N5O3Couleur et forme :SolidMasse moléculaire :467.42MraY-IN-1
<p>MraY-IN-1 inhibits MraY (IC50: 140μM), fights E. coli K12, B. subtilis W23, P. fluorescens (MIC50: 7-46μg/ml), for antimicrobial research.</p>Formule :C35H46N3O5Couleur et forme :SolidMasse moléculaire :588.76Norbinaltorphimine dihydrochloride
CAS :<p>Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.</p>Formule :C40H45Cl2N3O6Degré de pureté :98.17% - 99.88%Couleur et forme :SolidMasse moléculaire :734.71CHK1-IN-2
CAS :<p>CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).</p>Formule :C20H22N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.48BMS-986034
CAS :<p>BMS-986034 is a GPR119 agonist.</p>Formule :C24H24Cl2N6O4Couleur et forme :SolidMasse moléculaire :531.39EED ligand 1
<p>EED ligand 1: potent PRC2 inhibitor targeting EED subunit.</p>Formule :C19H19FN8OCouleur et forme :SolidMasse moléculaire :394.41RdRP-IN-5
CAS :<p>RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].</p>Formule :C23H21N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.43FGFR4-IN-7
<p>FGFR4-IN-7 is a covalent, reversible FGFR4 inhibitor (IC50: 0.42 μM) that blocks the FGFR4 signaling pathway, thereby inducing apoptosis.</p>Formule :C26H25Cl2N5O3Couleur et forme :SolidMasse moléculaire :526.41CDK1-IN-5
<p>CDK1-IN-5 is a selective inhibitor for CDK1 (IC50: 42.19 nM), CDK2, CDK5, halting cancer cell growth.</p>Formule :C27H26ClN5OSCouleur et forme :SolidMasse moléculaire :504.05VEGFR2-IN-1
CAS :<p>VEGFR2-IN-1 is a VEGFR2 inhibitor with antitumor activity used in the study of breast cancer.</p>Formule :C22H18N6SDegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :398.48WQ3810
CAS :<p>WQ3810 is an orally active fluoroquinolone, has potent antibacterial activities.</p>Formule :C22H22F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.44UNC7467
CAS :<p>UNC7467, potent IP6K2/1/6 inhibitor (4.9/8.9/1320 nM); lowers inositol pyrophosphates, minimal impact on other inositol phosphates; for obesity research.</p>Formule :C20H13NO3Degré de pureté :98.28% - 98.64%Couleur et forme :SoildMasse moléculaire :315.32Foroxymithine
CAS :<p>Foroxymithine is an inhibitor of angiotensin-converting enzyme.</p>Formule :C22H37N7O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.57Serlopitant
CAS :<p>Serlopitant is a selective antagonist of Neurokinin-1 (NK-1) receptor.</p>Formule :C29H28F7NO2Couleur et forme :SolidMasse moléculaire :555.53Anticancer agent 69
<p>Anticancer agent 69 targets PC3 cells (IC50=26 nM), raises ROS, lowers EGFR, and induces apoptosis.</p>Formule :C19H26N8SCouleur et forme :SolidMasse moléculaire :398.53MS8815
CAS :<p>MS8815 is a selective EZH2 PROTAC degrader with IC50 of 8.6 nM, used in triple-negative breast cancer research.</p>Formule :C65H87N9O8SCouleur et forme :SolidMasse moléculaire :1154.51PKCiota-IN-1
CAS :<p>PKCiota-IN-1: Strong PKC-ι inhibitor (IC50=2.7 nM); also blocks PKC-α/ε (IC50s=45/450 nM).</p>Formule :C25H22FN5OCouleur et forme :SolidMasse moléculaire :427.47HDAC-IN-9
<p>HDAC-IN-9, a dual tubulin/HDAC inhibitor, impedes A549 cell invasion/migration and shows strong anti-tumor/angiogenic effects.</p>Formule :C33H38N2O4Couleur et forme :SolidMasse moléculaire :526.67VEGFR-2-IN-26
CAS :<p>VEGFR-2-IN-26 inhibits VEGFR-2 (IC50: 15.5 nM), combating various cancers' cell growth.</p>Formule :C24H19F3N6O2Couleur et forme :SolidMasse moléculaire :480.44PTP1B-IN-16
<p>PTP1B-IN-16: selective benzimidazole inhibitor of PTP1B, Ki: 12.6 μM, potential for type 2 diabetes research.</p>Formule :C26H18ClN3O4SCouleur et forme :SolidMasse moléculaire :503.96AZD 4407
CAS :<p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>Formule :C19H21NO3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :375.5NI-Pano
<p>NI-Pano (CH-03) is a novel hypoxia-activated KDAC inhibitor capable of O2-dependent release of the compound panobinostat.</p>Formule :C26H28N6O4Couleur et forme :SolidMasse moléculaire :488.54FTI-2628
CAS :<p>FTI-2628 is a novel inhibitor of protein farnesyltransferase (FT), inhibiting the growth of P. falciparum in red blood cells and suppressing parasitemia.</p>Formule :C31H34N4O3SCouleur et forme :SolidMasse moléculaire :542.69LPA5 antagonist 2
<p>LPA5 antagonist 2, compound 65, water-soluble, reduces nociception, for inflammatory/neuropathic pain study.</p>Formule :C26H25FN2O4SCouleur et forme :SolidMasse moléculaire :480.55STAT3-IN-9
<p>STAT3-IN-9 hinders STAT3 at Tyr705, doesn't affect STAT1 Tyr701, induces apoptosis, and arrests cells in G2/M phase.</p>Formule :C22H21N3O4Couleur et forme :SolidMasse moléculaire :391.42HDAC8-IN-2
<p>HDAC8-IN-2 (5o) inhibits both smHDAC8 and hHDAC8 with IC50s of 0.27 μM, 0.32 μM, kills schistosome larvae, and lowers egg laying.</p>Formule :C21H16N2O5Couleur et forme :SolidMasse moléculaire :376.36Hoe 892
CAS :<p>Hoe 892 is a stable thia-thimo-analogue of prostacyclin and acts as a platelet aggregation inhibitor.</p>Formule :C20H33NO4SCouleur et forme :SolidMasse moléculaire :383.55BMS-986163
CAS :<p>BMS-986163, a prodrug, quickly becomes BMS-986169, a GluN2B inhibitor (Ki=4 nM, IC50=24 nM).</p>Formule :C23H28FN2O5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.45Glycotriosyl glutamine
CAS :<p>Glycotriosyl glutamine is a nephritogenoside analog.</p>Formule :C23H40N2O18Couleur et forme :SolidMasse moléculaire :632.57NTPDase-IN-3
CAS :<p>NTPDase-IN-3 inhibits NTPDase1/2/3/8 (IC50: 0.21/1.07/0.38/0.05 μM), useful for cancer and thrombosis research.</p>Formule :C22H24ClN3OS2Couleur et forme :SolidMasse moléculaire :446.03α-Glucosidase-IN-17
CAS :<p>α-Glucosidase-IN-17 (Compound 12B) is a potent and orally active inhibitor of α-glucosidase, demonstrating antidiabetic activity with an inhibitory</p>Formule :C30H27NO2SCouleur et forme :SolidMasse moléculaire :465.61Ranakinin
CAS :<p>Ranakinin is a novel tachykinin receptor agonist; from the brain of frog, Rana ridibunda.</p>Formule :C62H95N17O15SCouleur et forme :SolidMasse moléculaire :1350.59LXRβ agonist-3
CAS :<p>LXRβ agonist-3 is a potent and selective LXRβ (liver X receptor β) agonist (EC50: 0.095 μM).</p>Formule :C30H33N3O6SCouleur et forme :SolidMasse moléculaire :563.66G-479
CAS :<p>G-479, a potent MEK inhibitor and improved analogue of GDC-0623, has distributed polarity enhancing bioactivity.</p>Formule :C16H15FIN5O4Couleur et forme :SolidMasse moléculaire :487.22VEGFR-2-IN-25
CAS :<p>VEGFR-2-IN-25 (compound 5d) is a potent inhibitor of VEGFR-2 (IC50: 12.1 nM).</p>Formule :C24H22N6O2Couleur et forme :SolidMasse moléculaire :426.47NDT-30805
<p>NDT-30805, a triazolopyridine, blocks IL-1β in PBMC (IC50: 0.013μM) & NLRP3 inflammasome, for inflammation research.</p>Formule :C23H22N6SCouleur et forme :SolidMasse moléculaire :414.53CV 5975
CAS :<p>CV 5975 is a nonsulfhydryl ACE inhibitor that was investigated for use in hypertension and heart failure.</p>Formule :C22H31N3O5SCouleur et forme :SolidMasse moléculaire :449.56MSX-3
CAS :<p>MSX-3 is an antagonist of the A2A adenosine receptor and a prodrug of MSX-2.</p>Formule :C21H23N4Na2O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.389MMSET-IN-1
CAS :<p>MMSET-IN-1 is an inhibitor of multiple myeloma SET domain (MMSET, aka NSD2/WHSC1) .</p>Formule :C18H29N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :423.4716(S)-Iloprost
CAS :<p>Iloprost, a potent prostacyclin analog, binds to human IP & EP1 receptors with high affinity; inhibits platelet aggregation effectively.</p>Formule :C22H32O4Couleur et forme :SolidMasse moléculaire :360.49CI 992
CAS :<p>CI 992 is a novel potent inhibitor of primate renin.</p>Formule :C33H52N6O7S2Couleur et forme :SolidMasse moléculaire :708.93RSK4-IN-1
CAS :<p>RSK4-IN-1 is a compound exhibiting potent inhibition of RSK4, demonstrated by an IC50 value of 9.5 nM.</p>Formule :C19H20F2N4O3Couleur et forme :SolidMasse moléculaire :390.38RXR antagonist 1
<p>RXR antagonist 1 is a Retinoid X Receptor (RXR) modulator that exhibits high RXR antagonism (pA2: 8.06). RXR antagonist 1 can be used to study type 2 diabetes.</p>Formule :C28H33F3N2O3Couleur et forme :SolidMasse moléculaire :502.57PDHK-IN-4
<p>PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) & PDHK4 (IC50: 0.0122 μM), with potential for cancer research.</p>Formule :C24H25N5O3Couleur et forme :SolidMasse moléculaire :431.49KRAS G12D inhibitor 12
<p>KRAS G12D inhibitor 12 targets Ras protein for cancer research. (Patent WO2021108683A1, Compound 134)</p>Formule :C23H21ClFN5O3Couleur et forme :SolidMasse moléculaire :469.9LPM4870108
<p>LPM4870108: Potent, oral pan-Trk inhibitor, selective over ALK, with anti-tumor effects. TrkC IC50=0.2nM, TrkA IC50=2.4nM.</p>Formule :C20H19FN6O3Couleur et forme :SolidMasse moléculaire :410.4L 739749
CAS :<p>L 739749 is a CAAX peptidomimetic. It is also an inhibitor of farnesyl-protein transferase.</p>Formule :C24H41N3O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.73Deltasonamide 2 hydrochloride
<p>Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.</p>Formule :C30H40Cl2N6O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :683.71Anticancer agent 16
<p>Anticancer agent 16 showed good cytotoxic effects on HCT-116 cell line (IC50: 8.55 μM), NCI-H460 cell line (IC50: 5.41 μM) and SKOV3 cell line (IC50: 6.4 μM).</p>Formule :C27H33N5O6Couleur et forme :SolidMasse moléculaire :523.58Cathepsin K inhibitor 2
CAS :<p>Cathepsin K inhibitor 2 targets CTSK gene, may treat osteoporosis and osteoarthritis, detailed in patent WO2021147882A1.</p>Formule :C30H33F4N5O3Couleur et forme :SolidMasse moléculaire :587.61KRAS G12C inhibitor 46
CAS :<p>KRAS G12C inhibitor 46 is a potent inhibitor of KRAS G12C.</p>Formule :C32H33F2N7O2Couleur et forme :SolidMasse moléculaire :585.65Dehydrocrenatidine
CAS :<p>Dehydrocrenatidine (Kumujian G) is an inhibitor of JAK and induces cell apoptosis.</p>Formule :C15H14N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :254.28AKT-IN-3
CAS :<p>AKT-IN-3: potent oral Akt inhibitor with low hERG blockage. IC50: 1.4-1.7 nM for Akt1-3. Inhibits AGC kinases like PKA, PKC.</p>Formule :C23H23Cl2F2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :526.36MCTR1
CAS :<p>MCTR1, a pro-resolving mediator derived from DHA, promotes tissue repair and reduces inflammation by enhancing phagocytosis and decreasing eicosanoids.</p>Formule :C32H47N3O9SCouleur et forme :SolidMasse moléculaire :649.8TDI-11861
CAS :<p>TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.</p>Formule :C22H25ClF2N6O3Couleur et forme :SolidMasse moléculaire :494.92FCE-24379
CAS :<p>FCE-24379 is a selective antagonist of vascular serotonin receptors that has been shown to lowers blood pressure in hypertensive rats.</p>Formule :C20H22N4O2Couleur et forme :SolidMasse moléculaire :350.41264W94
CAS :<p>264W94 robustly inhibits IBAT, induces CYP7A1, and significantly reduces cholesterol.</p>Formule :C23H31NO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :417.56IRAK4-IN-18
<p>IRAK4-IN-18: Potent IRAK4 inhibitor (IC50: 15 nM), reduces IL23 in cells, prevents rat arthritis.</p>Formule :C24H25FN6O3Couleur et forme :SolidMasse moléculaire :464.49P-gp inhibitor 2
CAS :<p>Potent P-gp inhibitor 2 reverses Doxorubicin resistance in colorectal carcinoma cells with IC50 of 0.22 µM.</p>Formule :C29H26N2O6Couleur et forme :SolidMasse moléculaire :498.53FGFR4-IN-6
<p>FGFR4-IN-6: covalent, reversible FGFR4 blocker, 5.4 nM IC50, good oral bioavailability, reduces Hep3B2.1-7 tumors in mice, low toxicity.</p>Formule :C31H33N7O4Couleur et forme :SolidMasse moléculaire :567.64GKA50 quarterhydrate
<p>GKA50 quarterhydrate: glucokinase activator, EC50 of 33 nM, boosts insulin, cuts glucose in rats.</p>Formule :C26H30N2O7Couleur et forme :SolidMasse moléculaire :469.01Tubulin inhibitor 16
<p>Tubulin inhibitor 16 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 16 exhibits cytotoxicity in HepG2 cells [1].</p>Formule :C16H12FNO2Couleur et forme :SolidMasse moléculaire :269.27PTP1B-IN-21
<p>PTP1B-IN-21 inhibits PTP1B (IC50=1.56μM) selectively over TCPTP, a type 2 diabetes target.</p>Formule :C22H22O11Couleur et forme :SolidMasse moléculaire :462.4PqsR-IN-1
<p>PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.</p>Formule :C17H18ClN3OSCouleur et forme :SolidMasse moléculaire :347.86Bometolol Hydrochloride
CAS :<p>Bometolol Hydrochloride is a beta-adrenergic blocking compound used for the treatment of cardiovascular disease.</p>Formule :C25H33ClN2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.99HDAC1-IN-3
<p>HDAC1-IN-3 is a potent inhibitor of Pf HDAC1.</p>Formule :C22H24ClN7O2Couleur et forme :SolidMasse moléculaire :453.92EP4 receptor antagonist 2
CAS :<p>EP4 receptor antagonist 2 (compound 2-13) is a potent agonist of the EP4 receptor (IC50: 7.8 nM) and has antitumour effects.</p>Formule :C27H29N3O5Couleur et forme :SolidMasse moléculaire :475.54Cyclic-di-GMP sodium
<p>c-di-GMP sodium: STING activator, regulates bacteria biofilm, motility, virulence.</p>Formule :C20H24N10NaO14P2Couleur et forme :SolidMasse moléculaire :713.08464Gemilukast
CAS :<p>Gemilukast (ONO-6950) is a cysteinyl leukotriene 1 and 2 receptor inhibitor that inhibits bronchoconstriction and is used in the treatment of asthma.</p>Formule :C36H37F2NO5Degré de pureté :98.27% - 99.5%Couleur et forme :SolidMasse moléculaire :601.68HIV-1 inhibitor-52
CAS :<p>HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.</p>Formule :C46H72FNO5SCouleur et forme :SolidMasse moléculaire :770.13DMP 728
CAS :<p>DMP 728 is an antagonist of Glycoprotein IIb-IIIa.</p>Formule :C26H40N8O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :656.71Carbonic anhydrase inhibitor 3
<p>Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].</p>Formule :C15H17N3O3SCouleur et forme :SolidMasse moléculaire :319.38Taranabant
CAS :<p>Taranabant: potent CB1 receptor inverse agonist; inhibits agonists with 0.13 nM Ki in vitro.</p>Formule :C27H25ClF3N3O2Degré de pureté :99.06% - 99.06%Couleur et forme :SolidMasse moléculaire :515.9612(S)-HEPE
CAS :<p>12(S)-HEPE, made from EPA by 12-LO, is an anti-inflammatory ω-3 derivative affecting leukotriene formation.</p>Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.45Cathepsin C-IN-5
CAS :<p>Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.</p>Formule :C21H17ClN6OSCouleur et forme :SolidMasse moléculaire :436.92IRAK4-IN-11
<p>IRAK4-IN-11 (compound 6) is a potent inhibitor of IRAK4 with an IC 50 of 0.008 μM. IRAK4-IN-11 exhibits cell pIRAK4 potencies with an IC 50 of 0.19 μM [1].</p>Formule :C16H19N7OCouleur et forme :SolidMasse moléculaire :325.37LPA5 antagonist 1
<p>LPA5 antagonist 1: selective, potent (IC50=32 nM), high brain permeability, studies inflammatory/neuropathic pain.</p>Formule :C28H26N2O4SCouleur et forme :SolidMasse moléculaire :486.58Sulprostone
CAS :<p>EP3 and EP1 receptor agonist</p>Formule :C23H31NO7SDegré de pureté :98%Couleur et forme :White To Off-White SolidMasse moléculaire :465.56SARS-CoV-2-IN-22
CAS :<p>SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus inhibitor (IC50: 16.96 μM).</p>Formule :C27H24N2O3SCouleur et forme :SolidMasse moléculaire :456.56PDE4B/7A-IN-1
CAS :<p>5-HT1A antagonist; Ki=8nM, Kb=0.04nM. PDE4B IC50=80.4μM; PDE7A IC50=151.3μM. Good biofilm penetration, stable, anticognitive, antidepressant.</p>Formule :C25H35N3O3Couleur et forme :SolidMasse moléculaire :425.56U75302
CAS :<p>U75302 is an antagonist of thymosin beta-4 (TB4) receptor with a Ki value of 159 nM on guinea pig lung membranes.</p>Formule :C22H35NO3Degré de pureté :98%Couleur et forme :Light Yellow OilMasse moléculaire :361.52
