Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.524 produits)
- Apoptose(5.793 produits)
- Cycle cellulaire/point de contrôle(4.452 produits)
- Chromatine/Épigénétique(2.242 produits)
- Signalisation du cytosquelette(1.382 produits)
- Altération de l'ADN/réparation de l'ADN(2.826 produits)
- Endocrinologie/Hormones(3.507 produits)
- Enzyme(3.640 produits)
- GPCR/G-Protéine(8.333 produits)
- Immunologie et Inflammation(3.527 produits)
- Virus de la grippe(296 produits)
- Signalisation JAK/STAT(404 produits)
- Signalisation MAPK(1.203 produits)
- Transporteur membranaire/Canal ionique(2.792 produits)
- Métabolisme(9.449 produits)
- Microbiologie/Virologie(6.981 produits)
- Neuroscience(9.926 produits)
- Autres inhibiteurs(37.921 produits)
- Oxydation-Réduction(41 produits)
- Signalisation PI3K/Akt/mTOR(1.400 produits)
- Protéases/Protéasome(1.597 produits)
- Cellules souche et Dérivés(830 produits)
- Tyrosine Kinase/Adaptateurs(2.015 produits)
- Ubiquitination(1.650 produits)
Affichez 16 plus de sous-catégories
66639 produits trouvés pour "Inhibiteurs"
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WF-47-JS03
<p>WF-47-JS03: RET kinase inhibitor, crosses blood-brain barrier, 500x more selective for KDR, IC50: 1.7 nM in Ba/F3 cells, 5.3 nM in LC-2/ad lung cancer cells.</p>Formule :C30H38N6O2Couleur et forme :SolidMasse moléculaire :514.66E6201
CAS :<p>E6201, a dual kinase inhibitor, blocks MEK1/FLT3 and has anti-tumor/psoriasis effects with low IC50s: ERK2 (5.2 nM), JNK (91 nM), p38 MAPK (19 nM).</p>Formule :C21H27NO6Couleur et forme :SolidMasse moléculaire :389.44Disulergine
CAS :<p>Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.</p>Formule :C17H24N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.46MLKL-IN-1
<p>MLKL-IN-1 is a covalent inhibitor of MLKL with a Kd value of 50 μM.</p>Formule :C19H20N2O3Couleur et forme :SolidMasse moléculaire :324.37HPK1-IN-14
CAS :<p>HPK1-IN-14 is a potent inhibitor of HPK1. HPK1-IN-14 has potential for the study of HPK1-related diseases.</p>Formule :C24H23FN6O2Couleur et forme :SolidMasse moléculaire :446.48Cgs 25155
CAS :<p>Cgs 25155 is an orally active inhibitor of NEP 24.11.</p>Formule :C25H34N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.61PARP1-IN-5
<p>PARP1-IN-5 is a potent, selective, orally active, low-toxicity PARP-1 inhibitor with an IC50 value of 14.7 nM. PARP1-IN-5 can be used in cancer research.</p>Formule :C25H24N2O5SCouleur et forme :SolidMasse moléculaire :464.53Refametinib R enantiomer
CAS :<p>Refametinib R enantiomer (RDEA119 R enantiomer) is an MEK inhibitor with an EC50 of 2.0-15 nM.Refametinib (R enantiomer) has anticancer activity and can be used</p>Formule :C19H20F3IN2O5SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :572.34Meclocycline
CAS :<p>Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.</p>Formule :C22H21ClN2O8Couleur et forme :SolidMasse moléculaire :476.86HIV-1 inhibitor-18
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).</p>Formule :C27H31N3O6SCouleur et forme :SolidMasse moléculaire :525.62EGFR/HER2/DHFR-IN-1
<p>Potent EGFR/HER2/DHFR inhibitor for MCF-7 breast cancer; IC50: 0.153/0.108/0.291 μM; arrests G1/S phase, triggers apoptosis.</p>Formule :C14H11BrN4O2SCouleur et forme :SolidMasse moléculaire :379.23CXCR7 modulator 2
CAS :<p>CXCR7 modulator 2 is a 7-type C-X-C chemokine receptor (CXCR7) modulator with a Ki of 13 nM.</p>Formule :C29H42N6O3Couleur et forme :SolidMasse moléculaire :522.68USP7-IN-10
CAS :<p>USP7-IN-10 is a potent inhibitor of ubiquitin-specific protease 7 (USP7), exhibiting an inhibition concentration half-maximal (IC50) value of 13.39 nM.</p>Formule :C26H29ClN4O3SCouleur et forme :SolidMasse moléculaire :513.05Resolvin D1 methyl ester
CAS :<p>Resolvin D1, from docosahexaenoic acid via 15-/5-lipoxygenase, curbs acute inflammation; EC50 ~30 nM. Its methyl ester may enhance bioavailability.</p>Formule :C23H34O5Couleur et forme :SolidMasse moléculaire :390.51BRD7539
CAS :<p>BRD7539B: PfDHODH inhibitor, IC50 0.033μM; selective vs HsDHODH, IC50 >50μM.</p>Formule :C23H22FN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :391.44IRAK4-IN-14
CAS :<p>IRAK4-IN-14 is a selective, potent, orally active IRAK4 inhibitor (IC50: 0.003 μM) with favorable PK parameters in rats and mice. effect.</p>Formule :C25H28FN9OCouleur et forme :SolidMasse moléculaire :489.55TBK1/IKKε-IN-1
CAS :<p>TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).</p>Formule :C28H26N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.53OP-2507
CAS :<p>OP-2507, a prostacyclin agonist, is used potentially for the treatment of hepatic insufficiency and hypertension.</p>Formule :C25H41NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.6α-Glucosidase-IN-14
<p>α-Glucosidase-IN-14 is a potent inhibitor of α-glucosidase (IC50: 5.22 μM).</p>Formule :C24H27N5O4S2Couleur et forme :SolidMasse moléculaire :513.63Nikkomycin Z
CAS :<p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>Formule :C20H25N5O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.44Heme Oxygenase-2-IN-1
<p>Heme Oxygenase-2-IN-1 is a selective HO-2 inhibitor with IC50s: 14.9 μM (HO-1), 0.9 μM (HO-2).</p>Formule :C19H17N3O2Couleur et forme :SolidMasse moléculaire :319.36Beloxepin
CAS :<p>Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.</p>Formule :C19H21NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.38FXIa-IN-9
CAS :<p>FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.</p>Formule :C23H18Cl2F3N9O2Couleur et forme :SolidMasse moléculaire :580.35ATM Inhibitor-4
<p>ATM Inhibitor -4: selective, potent (IC50: 0.32 nM), inhibits PI3K family, stable, stops mTOR at 1 μM.</p>Formule :C26H29FN6O3Couleur et forme :SolidMasse moléculaire :492.55PptT-IN-3
<p>PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.</p>Formule :C16H27N5O3SCouleur et forme :SolidMasse moléculaire :369.48L 671776
CAS :<p>L 671776 is an inositol monophosphatase inhibitor.</p>Formule :C23H32O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :388.5JH-XVII-10
<p>JH-XVII-10: potent, oral DYRK1A/B inhibitor (IC50: 3/5 nM), shows antitumor activity in HNSCC.</p>Formule :C21H16F4N8OCouleur et forme :SolidMasse moléculaire :472.42R,4S-Sacubitril
CAS :<p>2R,4S-Sacubitril (Sacubitril Enantiomer) is the impurity of Sacubitril which is a neprilysin inhibitor.</p>Formule :C24H28NO51CaDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.49PI3K-IN-35
CAS :<p>PI3K-IN-35 (6l) selectively inhibits PI3K-α, β, δ (IC50: 13.98, 7.22, 10.94 μM), blocks G2/M phase, induces apoptosis, and is useful in leukemia research.</p>Formule :C25H23N7O2Couleur et forme :SolidMasse moléculaire :453.522-HDHA
CAS :<p>22-HDHA is an oxidation product of docosahexaenoic acid .</p>Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.49EGFR-IN-44
<p>EGFR-IN-44: potent EGFR kinase inhibitor, orally active, IC50 4.11 nM, 33.57% bioavailability, induces apoptosis, for lung cancer study.</p>Formule :C27H29ClN6O2SCouleur et forme :SolidMasse moléculaire :537.08YM-202074
CAS :<p>YM-202074: Selective mGlu1 antagonist, binds allosteric site (Ki=4.8 nM), inhibits mGlu1 (IC50=8.6 nM).</p>Formule :C22H30N4O2SCouleur et forme :SolidMasse moléculaire :414.56(S)-JDQ-443
CAS :<p>(S)-JDQ-443, an isomer of JDQ-443, is a selective, potent oral KRAS G12C inhibitor with antitumor properties.</p>Formule :C29H28ClN7OCouleur et forme :SolidMasse moléculaire :526.03GAT564
<p>GAT564, an allosteric CB1R modulator, shows EC50s of 87 nM (cAMP) & 320 nM (β-arrestin2) and lowers IOP effectively in glaucoma mice.</p>Formule :C20H16N2O2SCouleur et forme :SolidMasse moléculaire :348.42(2R,3S)-Azelaprag
CAS :<p>(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist</p>Formule :C25H29N7O4SDegré de pureté :97.47% - >99.99%Couleur et forme :SoildMasse moléculaire :523.61L-threo-Sphingosine C-18
CAS :<p>L-threo-Sphingosine C-18 is a protein kinase C inhibitor.</p>Formule :C18H37NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.49HDAC/Top-IN-1
CAS :<p>HDAC/Top-IN-1, an oral HDAC/Top inhibitor, targets HDAC1-3,6,8 with low IC50s; blocks S-phase & induces apoptosis in HEL cells.</p>Formule :C29H25FN4O4Couleur et forme :SolidMasse moléculaire :512.53LY 292728
CAS :<p>LY 292728 is a highly potent antagonist of leukotriene B4 receptor.</p>Formule :C34H29FO9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :600.59DMP-728 free base
CAS :<p>DMP-728 free base is a highly potent and selective GPIIbDIIa antagonist</p>Formule :C25H36N8O7Couleur et forme :SolidMasse moléculaire :560.60ATR-IN-11
<p>ATR-IN-11, a potent ATR kinase inhibitor, shows promise as a lead for DNA damage response-targeted cancer drugs.</p>Formule :C25H30N6O2Couleur et forme :SolidMasse moléculaire :446.54EGFR-IN-58
<p>EGFR-IN-58 is a potent, selective, ATP-competitive inhibitor of EGFR. EGFR-IN-58 exhibits significant cytotoxicity against melanoma, colon and blood cancers.</p>Formule :C31H30FN7OCouleur et forme :SolidMasse moléculaire :535.61Furaprevir
CAS :<p>Furaprevir is an HCV NS3/4A Inhibitor</p>Formule :C47H56N6O10SCouleur et forme :SolidMasse moléculaire :897.05Cacospongionolide B
CAS :<p>Cacospongionolide B from Fasciospongia cavernosa inhibits secretory phospholipase A2, curbing inflammation.</p>Formule :C25H36O4Couleur et forme :SolidMasse moléculaire :400.55CHF-6366
CAS :<p>CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.</p>Formule :C42H48N6O8Couleur et forme :SolidMasse moléculaire :764.87Saprisartan potassium
CAS :<p>Saprisartan potassium is an Angiotensin II Type 1 receptor antagonist and antihypertensive agent.</p>Formule :C25H21BrF3KN4O4SCouleur et forme :SolidMasse moléculaire :649.52Seco-Duocarmycin SA
CAS :<p>Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.</p>Formule :C25H24ClN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.93Vanin-1-IN-3
<p>Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC 50 of 0.038 μM [1].</p>Formule :C17H22F3NO5Couleur et forme :SolidMasse moléculaire :377.36COX-2-IN-6
CAS :<p>COX-2-IN-6: Potent, selective COX-2 inhibitor; oral; IC50 0.84μM, Ki 69nM; blocks PGE2 synthesis; prevents colorectal cancer.</p>Formule :C20H27NO6SDegré de pureté :99.29% - 99.69%Couleur et forme :SoildMasse moléculaire :409.5Idraparinux Na
CAS :<p>Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa Inhibitor</p>Formule :C38H55Na9O49S7Couleur et forme :SolidMasse moléculaire :1727.14CXN37378
CAS :<p>CXN37378, aka NAP, is a potent MOR-selective antagonist with no official name yet, termed per MedKoo Nomenclature.</p>Formule :C27H31N3O4Couleur et forme :SolidMasse moléculaire :461.55VEGFR-2-IN-16
<p>VEGFR-2-IN-16 (Compound 15b) is a potent inhibitor of VEGFR-2 (IC50: 86.36 nM) that exhibits antitumour effects.</p>Formule :C21H13Cl2N3O2Couleur et forme :SolidMasse moléculaire :410.25Elacestrant S enantiomer dihydrochloride
<p>Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.</p>Formule :C30H40Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.56MDL-27788
CAS :<p>MDL-27788 is a tricyclic inhibitor.</p>Formule :C24H26N2O5SCouleur et forme :SolidMasse moléculaire :454.54Galectin-8-IN-1
<p>Galectin-8-IN-1 selectively binds galectin-8N with 48 μM affinity, 15x more than galectin-3.</p>Formule :C16H18N2O6Couleur et forme :SolidMasse moléculaire :334.32ZD6021
CAS :<p>ZD6021 is an antagonist of neurokinin 1 receptor.</p>Formule :C35H35Cl2N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :632.64CDK9-IN-11
CAS :<p>CDK9-IN-11 is a potent CDK9 inhibitor that is the ligand for the PROTAC CDK9 Degrader-1 [1].</p>Formule :C20H25N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :371.43Ambuic acid
CAS :<p>Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.</p>Formule :C19H26O6Couleur et forme :SolidMasse moléculaire :350.41GnRH-R antagonist 1
CAS :<p>Compound 21a: Oral GnRH-R antagonist, IC50=0.57 nM, potent against prostate cancer/prevents LH surges.</p>Formule :C31H28F5N7O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :721.65HDAC-IN-35
<p>HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.</p>Formule :C17H13ClF3N3O3Couleur et forme :SolidMasse moléculaire :399.75Urease-IN-1
<p>Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).</p>Formule :C17H12BrFN4O2SCouleur et forme :SolidMasse moléculaire :435.27PF-5177624
CAS :<p>PF-5177624 is a selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells.</p>Formule :C25H25FN8O2Couleur et forme :SolidMasse moléculaire :488.52PDHK-IN-3
<p>PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].</p>Formule :C17H16N2O2Couleur et forme :SolidMasse moléculaire :280.32TRK-IN-12
CAS :<p>TRK-IN-12 (9e), a macrocyclic TRK inhibitor (G595R IC50=13.1 nM), outperforms LOXO-101 in Ba/F3-NTRK1 cells.</p>Formule :C18H19ClFN5O3SCouleur et forme :SolidMasse moléculaire :439.89JAK3-IN-13
<p>JAK3-IN-13: Oral JAK3 inhibitor, selective & potent. Acts on NK1, JNK2, JNK3, Tyk2. Anti-tumor. IC50: JNK3, 8 nM; Tyk2, 365 nM; JNK2, 2039 nM; NK1, 4728 nM.</p>Formule :C25H33ClN6O5Couleur et forme :SolidMasse moléculaire :533.02Piceid 6″-O-azelaic acid ester
<p>Piceid 6″-O-azelaic acid ester exhibited strong intracellular tyrosinase inhibition and decolorization activity.</p>Formule :C24H36O10Couleur et forme :SolidMasse moléculaire :484.54RAD51-IN-6
CAS :<p>RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)</p>Formule :C27H40N3O5PSCouleur et forme :SolidMasse moléculaire :549.66AM Toxin II
CAS :<p>AM Toxin II is a Cyclic tetradepsipeptide isolated from Alternaria mali.</p>Formule :C22H29N3O5Couleur et forme :SolidMasse moléculaire :415.49AM8936
<p>AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.</p>Formule :C25H33NO3Couleur et forme :SolidMasse moléculaire :395.53Trypanothione synthetase-IN-4
<p>Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).</p>Formule :C29H52INO2Couleur et forme :SolidMasse moléculaire :573.63TT15
CAS :<p>TT15 is an agonist of the GLP-1R.</p>Formule :C51H44Cl2N4O6Couleur et forme :SolidMasse moléculaire :879.82UK-432097
CAS :<p>UK 432097 is an adenosine A2A agonist.</p>Formule :C40H47N11O6Couleur et forme :SolidMasse moléculaire :777.87PD-1-IN-17
CAS :<p>PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at 100 nM.</p>Formule :C13H22N6O7Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :374.3520S Proteasome-IN-4
CAS :<p>20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.</p>Formule :C20H18ClF2N3O3Couleur et forme :SolidMasse moléculaire :421.83Iralukast (CGP 45715A)
CAS :<p>Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.</p>Formule :C38H37F3O8SCouleur et forme :SolidMasse moléculaire :710.76Acetomycin
CAS :<p>Acetomycin, a γ-lactone from S. ramulosus, halts HCT-8 colon and L1210 leukemia cell growth.</p>Formule :C10H14O5Couleur et forme :SolidMasse moléculaire :214.22BM635 mesylate
<p>BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.</p>Formule :C26H33FN2O4SCouleur et forme :SolidMasse moléculaire :488.61ORIC-101
CAS :<p>ORIC-101 is a highly effective and selective glucocorticoid receptor antagonist (EC50: 5.6 nM). It also has anti-cancer activity.</p>Formule :C34H47NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.74(RS)-AMPA
CAS :<p>(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.</p>Formule :C7H10N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :186.17Desacetylravidomycin
CAS :<p>Desacetylravidomycin is a new inhibitor of IL-4 signal transduction, produced by Streptomyces sp. WK-6326.</p>Formule :C29H31NO8Couleur et forme :SolidMasse moléculaire :521.56Tetrahydrouridine dihydrate
<p>THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.</p>Formule :C9H20N2O8Couleur et forme :SolidMasse moléculaire :284.26iNOS/PGE2-IN-1
<p>iNOS/PGE2-IN-1: iNOS/PGE2 inhibitor, reduces LPS-induced NO, low ulcer risk, anti-inflammatory.</p>Formule :C26H22ClN3O4Couleur et forme :SolidMasse moléculaire :475.92GNTI TFA
CAS :<p>GNTI TFA is a selective kappa opioid receptor antagonist.</p>Formule :C31H31F6N5O7Couleur et forme :SolidMasse moléculaire :699.60IDO1-IN-14
<p>IDO1-IN-14 is an IDO1 enzyme inhibitor with an IC50 of 396.9 nM and suppresses HeLa cell activity with an EC50 of 3393 nM.</p>Formule :C18H12Cl2FN3O2Couleur et forme :SolidMasse moléculaire :392.21YM 202074
CAS :<p>metabotropic glutamate receptor type 1 (mGlu1) antagonist</p>Formule :C56H72N8O16S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1177.34Dihydro-β-erythroidine hydrobromide
CAS :<p>Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs).</p>Formule :C16H22BrNO3Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :356.26Rodatristat ethyl
CAS :<p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.</p>Formule :C29H31ClF3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :590.04G108
CAS :<p>G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.</p>Formule :C16H14Cl2N4O2Degré de pureté :99.13% - 99.75%Couleur et forme :SolidMasse moléculaire :365.21SHP2-IN-9
<p>SHP2-IN-9: Potent SHP2 inhibitor, IC50=1.174 μM, 85x SHP1 selectivity, crosses blood-brain barrier, hampers cancer growth.</p>Formule :C20H20FN3O2SCouleur et forme :SolidMasse moléculaire :385.46UNC7467
CAS :<p>UNC7467, potent IP6K2/1/6 inhibitor (4.9/8.9/1320 nM); lowers inositol pyrophosphates, minimal impact on other inositol phosphates; for obesity research.</p>Formule :C20H13NO3Degré de pureté :98.28% - 98.64%Couleur et forme :SoildMasse moléculaire :315.32MS8815
CAS :<p>MS8815 is a selective EZH2 PROTAC degrader with IC50 of 8.6 nM, used in triple-negative breast cancer research.</p>Formule :C65H87N9O8SCouleur et forme :SolidMasse moléculaire :1154.51BRD-7880
CAS :<p>BRD-7880 is a potent and highly specific inhibitor of aurora kinases B and C.</p>Formule :C32H38N4O7Couleur et forme :SolidMasse moléculaire :590.67COX-2-IN-12
<p>COX-2-IN-12: Potent, selective COX-2 inhibitor, IC50=19.98μM, safe anti-inflammatory with low acute toxicity.</p>Formule :C17H19NO3Couleur et forme :SolidMasse moléculaire :285.34Cenicriviroc Sulfone
CAS :<p>Cenicriviroc Sulfone, a Cenicriviroc derivative, inhibits CCR2/CCR5 to block HIV entry into cells.</p>Formule :C41H52N4O5SCouleur et forme :SolidMasse moléculaire :712.94KRAS G12C inhibitor 56
CAS :<p>KRAS G12C inhibitor 56, a powerful inhibitor of SOS1 with an inhibitory concentration (IC50) of 1.6 nM, holds promise for use in cancer research.</p>Formule :C32H39N7O4SCouleur et forme :SolidMasse moléculaire :617.76PKCiota-IN-1
CAS :<p>PKCiota-IN-1: Strong PKC-ι inhibitor (IC50=2.7 nM); also blocks PKC-α/ε (IC50s=45/450 nM).</p>Formule :C25H22FN5OCouleur et forme :SolidMasse moléculaire :427.47VEGFR-2-IN-10
<p>VEGFR-2-IN-10 has enhanced antiangiogenic potency against VEGFR2 phosphorylation induced by VEGF with an IC50 value of 0.7 μM and no cytotoxic effects.</p>Formule :C20H21N3O2Couleur et forme :SolidMasse moléculaire :335.4Adecypenol
CAS :<p>Adecypenol is a unique adenosine deaminase inhibitor. It shows effective inhibitory activity against calf intestinal adenosine deaminase.</p>Formule :C12H16N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :280.28LXR agonist 2
<p>LXR agonist 2 is a potent agonist of the LXR (liver X receptor). LXR agonist 2 stabilises NCOA1 (coactivator), which in turn agonises the LXR.</p>Formule :C35H40ClN3O3Couleur et forme :SolidMasse moléculaire :586.16PD-L1-IN-1
<p>PD-L1-IN-1, potent PD-L1 inhibitor with 115 nM IC50, suppresses tumors, boosts immune response, and spares healthy cells.</p>Formule :C21H23N5O2Couleur et forme :SolidMasse moléculaire :377.44Ranakinin
CAS :<p>Ranakinin is a novel tachykinin receptor agonist; from the brain of frog, Rana ridibunda.</p>Formule :C62H95N17O15SCouleur et forme :SolidMasse moléculaire :1350.59Suloctidil HCl
CAS :<p>Suloctidil HCl is a peripheral vascular dilator.</p>Formule :C20H36ClNOSCouleur et forme :SolidMasse moléculaire :374.02LXRβ agonist-3
CAS :<p>LXRβ agonist-3 is a potent and selective LXRβ (liver X receptor β) agonist (EC50: 0.095 μM).</p>Formule :C30H33N3O6SCouleur et forme :SolidMasse moléculaire :563.66Retezorogant
CAS :<p>Retezorogant is a retinoic acid receptor-related orphan receptor gamma (RORγ) antagonist.</p>Formule :C23H33ClN2O3Couleur et forme :SolidMasse moléculaire :420.97ACHN-975 TFA
CAS :<p>ACHN-975 TFA is a selective LpxC inhibitor with a subnanomolar inhibitory. It is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL).</p>Formule :C22H24F3N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :483.4377VRT-18858
CAS :<p>VRT-18858 is a metabolite of VX-740.</p>Formule :C24H25N5O7Couleur et forme :SolidMasse moléculaire :495.48Fipravirimat
CAS :<p>Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.</p>Formule :C43H67FN2O4SCouleur et forme :SolidMasse moléculaire :727.07PF-06263276
CAS :<p>PF-06263276 selectively inhibits pan-JAK with IC50: JAK1 (2.2 nM), JAK2 (23.1 nM), JAK3 (59.9 nM), TYK2 (29.7 nM).</p>Formule :C31H31FN8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :566.63BM635 hydrochloride (1493762-74-5 free base)
<p>BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).</p>Formule :C25H30ClFN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.97BAY-7598
CAS :<p>BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).</p>Formule :C28H31N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.56HDAC10-IN-1
<p>HDAC10-IN-1 is a potent, selective HDAC10 inhibitor (IC50=58 nM) affecting autophagy in FLT3-ITD+ acute myeloid leukemia cells.</p>Formule :C18H23N3O2Couleur et forme :SolidMasse moléculaire :313.39Tubulin inhibitor 22
<p>Compound 4c: Strong tubulin inhibitor with anti-cancer & anti-angiogenic effects; halts MGC-803 cells in G2/M, triggers Caspase-mediated apoptosis.</p>Formule :C20H17BrFNO4Couleur et forme :SolidMasse moléculaire :434.26GNE684
CAS :<p>GNE684 inhibits RIP1; Ki app: 21 nM (human), 189 nM (mouse), 691 nM (rat).</p>Formule :C23H24N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.48MMSET-IN-1
CAS :<p>MMSET-IN-1 is an inhibitor of multiple myeloma SET domain (MMSET, aka NSD2/WHSC1) .</p>Formule :C18H29N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :423.47Triphen diol
CAS :<p>Triphen diol, a phenol diol, fights pancreatic cancer & cholangiocarcinoma, inducing apoptosis via caspase-dependent & -independent paths.</p>Formule :C22H20O4Couleur et forme :SolidMasse moléculaire :348.39Tarloxotinib bromide
CAS :Tarloxotinib bromide (TH-4000) is an irreversible inhibitor of EGFR/HER2.Formule :C24H24Br2ClN9O3Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :681.77EGFR/HER2-IN-7
<p>EGFR/HER2-IN-7: Potent, selective dual inhibitor for MCF-7 cancer; IC50: EGFR 0.18μM, HER2 0.146μM, DHFR 0.907μM.</p>Formule :C19H21N3O2SCouleur et forme :SolidMasse moléculaire :355.45Amrubicin HCl
CAS :<p>Amrubicin (SM-5887), an anthracycline, treats lung cancer by inhibiting DNA replication and topoisomerase II, with less cardiac toxicity.</p>Formule :C25H25NO9Couleur et forme :SolidMasse moléculaire :483.47Lavendomycin
CAS :<p>Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.</p>Formule :C29H50N10O8Couleur et forme :SolidMasse moléculaire :666.77Vibegron
CAS :<p>Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).</p>Formule :C26H28N4O3Couleur et forme :SolidMasse moléculaire :444.53LT-850-166
<p>LT-850-166 is a potent inhibitor of FLT3 and has shown efficacy in overcoming a wide range of FLT3 mutations.</p>Formule :C30H29Cl2N7OCouleur et forme :SolidMasse moléculaire :574.5M-89 MLL inhibitor
CAS :<p>M-89, a potent Menin-MLL blocker: Kd 1.4 nM, IC50 25 nM for MV4;11 cells, 55 nM for MOLM-13, >100x selective over HL-60.</p>Formule :C37H47N5O4SCouleur et forme :SolidMasse moléculaire :657.87YW3-56
CAS :<p>YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.</p>Formule :C27H32ClN5O2Couleur et forme :SolidMasse moléculaire :494.03Antitumor agent-78
<p>Antitumor agent-78 blocks GPx-4, raises COX2, triggers apoptosis, halts EMT, and stifles cancer cell growth and migration.</p>Couleur et forme :SoildRaloxifene N-Oxide
CAS :<p>Raloxifene N-Oxide is a Raloxifene oxidative degradation product.</p>Formule :C28H27NO5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :489.58(±)-HIP-B
CAS :<p>(±)-HIP-B is an excitatory amino acid transporter blocker.</p>Formule :C6H8N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :172.14BRD5631
CAS :<p>BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway.</p>Formule :C30H35N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.62BMS-554417
CAS :<p>BMS-554417 inhibits IGF-IR/insulin receptors, curbing cell proliferation and tumor growth, with IC50 values of 120 nm–>8.5 μmol/L.</p>Formule :C28H30ClN7O2Couleur et forme :SolidMasse moléculaire :532.049(S)-HEPE
CAS :<p>9(S)-HEPE is a monohydroxy fatty acid derived from EPA. The biological activity of 9(S)-HEPE has not been documented.</p>Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.45HDAC6/HSP90-IN-2
<p>HDAC6/HSP90-IN-2, a cancer research chemical, inhibits HDAC6 & Hsp90 with IC50s of 105.7 & 61 nM.</p>Formule :C19H22N2O5Couleur et forme :SolidMasse moléculaire :358.39HER2-IN-11
<p>HER2-IN-11 is a psoralen derivative that induces apoptosis. HER2-IN-11 shows light-activated cytotoxicity and also exhibits anti-breast cancer activity [1].</p>Formule :C17H11NO6Couleur et forme :SolidMasse moléculaire :325.27ND-654
CAS :<p>ND-654 is an acetyl CoA carboxylase inhibitor.</p>Formule :C29H33N3O8SCouleur et forme :SolidMasse moléculaire :583.65GC 14
CAS :<p>GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 200 nM and 35 nM for hTRα and hTRβ, respectively.</p>Formule :C26H27NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :449.511-Oxahomoaminopterin
CAS :<p>11-Oxahomoaminopterin exhibits antifolate activity against two folate-requiring microorganisms and inhibited Lactobacillus casei DHFR.</p>Formule :C20H21N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.42HBV-IN-11
CAS :<p>HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).</p>Formule :C21H24ClNO6Couleur et forme :SolidMasse moléculaire :421.87MI-1481
CAS :<p>MI-1481: potent MML1 inhibitor, IC50 3.6 nM; disrupts menin-MLL1, active in MLL leukemia.</p>Formule :C29H30F3N7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :597.65BU09059
CAS :<p>BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).</p>Formule :C28H37N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.61U92016A hydrochloride
CAS :<p>U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.</p>Formule :C19H26ClN3Couleur et forme :SolidMasse moléculaire :331.89Carumonam Sodium
CAS :<p>Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials.</p>Formule :C12H12N6Na2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.37Tubulin inhibitor 17
<p>Compound 3b inhibits tubulin polymerization, IC50 12.38 µM, with anticancer properties and promotes cell apoptosis.</p>Formule :C17H16N2OCouleur et forme :SolidMasse moléculaire :264.32BMS-986034
CAS :<p>BMS-986034 is a GPR119 agonist.</p>Formule :C24H24Cl2N6O4Couleur et forme :SolidMasse moléculaire :531.39MraY-IN-1
<p>MraY-IN-1 inhibits MraY (IC50: 140μM), fights E. coli K12, B. subtilis W23, P. fluorescens (MIC50: 7-46μg/ml), for antimicrobial research.</p>Formule :C35H46N3O5Couleur et forme :SolidMasse moléculaire :588.76ERK-IN-2
CAS :<p>ERK-IN-2, an ERK2 inhibitor, exhibits an IC50 value of 1.8 nM. At doses greater than 10 μM, it may induce off-target toxicity and/or activity [1].</p>Formule :C16H18ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.80TAK-828F
CAS :<p>TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.</p>Formule :C28H32FN3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.57BAY-899
CAS :<p>BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.</p>Formule :C25H19F2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.45Musettamycin
CAS :<p>Musettamycin triggers erythroid differentiation in blood cells, acts like anthracycline antibiotics, but only inhibits gram-positive bacteria.</p>Formule :C36H45NO14Couleur et forme :SolidMasse moléculaire :715.74Dopamine D3 receptor antagonist-2
<p>Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.</p>Formule :C23H27Cl2N3O3Couleur et forme :SolidMasse moléculaire :464.38FWM-1
<p>FWM-1 blocks SARS-CoV-2 NSP13, hinders ATP binding, with -328.6 kcal/mol binding energy.</p>Formule :C15H11ClN4O4S2Couleur et forme :SolidMasse moléculaire :410.86GNE-2256
CAS :<p>GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has</p>Formule :C24H27FN6O4Couleur et forme :SolidMasse moléculaire :482.51Glycyl H-1152 hydrochloride
CAS :<p>Glycyl-H-1152 is a potent ROCK-II inhibitor (IC50=11.8 nM) with high selectivity over CaMKII, PKG, Aurora A, PKA, and PKC. Better than Y-27632 and HA-1077.</p>Formule :C18H26Cl2N4O3SCouleur et forme :SolidMasse moléculaire :449.39M-COPA
CAS :<p>M-COPA disrupts Golgi, blocks MET & Arf1 activation, and inhibits angiogenesis via VEGFR & NF-kB pathways.</p>Formule :C25H34N2O2Couleur et forme :SolidMasse moléculaire :394.55DHFR-IN-4
CAS :<p>DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer.</p>Formule :C18H21N5O2SDegré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :371.46JBJ-02-112-05
CAS :<p>JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC 50 of 15 nM for EGFR L858R/T790M [1].</p>Formule :C27H20N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.54S-HP210
<p>S-HP210: selective GR modulator, blocks NF-κB (IC50: 1.92 μM), non-toxic to mouse fibroblasts.</p>Formule :C22H19N3O2S2Couleur et forme :SolidMasse moléculaire :421.54NSC381467
CAS :<p>NSC381467: Potent, oral EGFR-TK inhibitor with strong antiproliferative effects, promising for cancer research.</p>Formule :C20H16O7Couleur et forme :SolidMasse moléculaire :368.34GSK 932121
CAS :<p>GSK 932121: potent antimalarial, targets P. falciparum by inhibiting cytochrome bc1 in the electron transport chain.</p>Formule :C20H15ClF3NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :425.79NDM-1 inhibitor-3
<p>NDM-1 inhibitor-3 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor (Ki : 4 μM) widely found in nature and is associated with antibiotic resistance.</p>Formule :C16H12O4Degré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :268.26Z-FY-CHO
CAS :<p>Pyridoxal (Pyridoxaldehyde), a component of vitamin B6, is an aldehyde obtained by oxidizing pyridoxine and is widely found in plants and animals.</p>Formule :C26H26N2O5Degré de pureté :95.88%Couleur et forme :SolidMasse moléculaire :446.5ZLM-66
<p>ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.</p>Couleur et forme :SolidBET-IN-1
<p>BET-IN-1 is a potent inhibitor of BET, exhibiting good brain permeability and a reasonable metabolic stability.</p>Formule :C23H24ClFN4O3SCouleur et forme :SolidMasse moléculaire :490.98CDK4/6-IN-3
CAS :<p>CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM) used for the treatment of glioblastoma. It inhibits CDK1 with a Ki of 110 nM.</p>Formule :C25H31FN8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.57O4
CAS :<p>O4 is a novel stabilizer of amyloid- fibrils. O4 used for accelerating the formation of end-stage mature fibrils.</p>Formule :C24H15NO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :429.38Sacibertinib
CAS :<p>Sacibertinib inhibits Trk, targeting EGFR-TK (EC50 110 nM) & HER2 (EC50 244 nM), with anticancer properties.</p>Formule :C32H31ClN6O4Couleur et forme :SolidMasse moléculaire :599.08RTIOX-372
CAS :<p>RTIOX-372 is a potent and selective orexin-1 receptor antagonist.</p>Formule :C30H39N5O3Couleur et forme :SolidMasse moléculaire :517.66Orvepitant
CAS :<p>Orvepitant is a potent and selective NK1 antagonist, which may be potentially useful for patients with major depressive disorder (MDD), anxiety and insomnia.</p>Formule :C31H35F7N4O2Couleur et forme :SolidMasse moléculaire :628.62LRRK2-IN-2
CAS :<p>LRRK2-IN-2: selective, potent LRRK2 inhibitor, IC50 of 0.6 nM, oral, crosses blood-brain barrier, for Parkinson's research.</p>Formule :C23H23Cl2F3N6O2Couleur et forme :SolidMasse moléculaire :543.37Unoprostone isopropyl
CAS :<p>Unoprostone isopropyl, a prostanoid and synthetic docosanoid, is approved for the treatment of ocular hypertension and open-angle glaucoma.</p>Formule :C25H44O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.61S39625
CAS :<p>S39625 is a stable, potent topoisomerase I inhibitor with anticancer properties, resistant to efflux transporters, inducing gamma-H2AX at nanomolar levels.</p>Formule :C25H22N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.45BRD2879
CAS :<p>BRD2879 is a potent and cell-active inhibitor of IDH1-R132H (IC50 = 50 nM).</p>Formule :C30H38FN3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :571.70Antitubulin agent 1
<p>Antitubulin agents-1 disrupts microtubules, ups α-tubulin acetylation, and has anticancer properties.</p>Formule :C21H19N3O3Couleur et forme :SolidMasse moléculaire :361.39BI-2540
CAS :<p>BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .</p>Formule :C24H15ClF5NO5Couleur et forme :SolidMasse moléculaire :527.833'-Hydroxy Repaglinide
CAS :<p>'3'-Hydroxy Repaglinide, a CYP2C8 metabolite of Repaglinide, treats type II diabetes.</p>Formule :C27H36N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.59Oxeclosporin
CAS :<p>Oxeclosporin is a hydroxyethyl derivative of serine(8)-cyclosporine; inhibits proliferation and functions of lymphocytes.</p>Formule :C64H115N11O14Couleur et forme :SolidMasse moléculaire :1262.66Ro-24-4736
CAS :<p>Ro 24-4736 is an effective and selective platelet-activating factor antagonist.</p>Formule :C31H20ClN5OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :546.04Indoluidin E
<p>Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.</p>Formule :C28H30N4O2Couleur et forme :SolidMasse moléculaire :454.56Verrucarin A
CAS :<p>Verrucarin A, a mycotoxin from Myrothecium verrucaria, inhibits protein synthesis, leukemia growth, and triggers apoptosis.</p>Formule :C27H34O9Couleur et forme :SolidMasse moléculaire :502.55LXRβ agonist-2
CAS :LXRβ agonist-2 is a highly potent and β-selective liver X receptor (LXRβ) agonist with EC50 of 7 nM.Formule :C32H31F6N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :683.59SB-423557
CAS :<p>SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nM</p>Formule :C28H36N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.60P2X7 receptor antagonist-1
<p>P2X7 receptor antagonist-1 is a purinergic P2X7 receptor antagonist with anti-neuroinflammatory effects.</p>Formule :C22H20F4N2O3Couleur et forme :SolidMasse moléculaire :436.4Dinordrin I diacetate
CAS :<p>Dinordrin I diacetate is an implantation inhibitor and hormone.</p>Formule :C25H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.52MSX-3
CAS :<p>MSX-3 is an antagonist of the A2A adenosine receptor and a prodrug of MSX-2.</p>Formule :C21H23N4Na2O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.389Faldaprevir sodium
CAS :<p>Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.</p>Formule :C40H48BrN6NaO9SCouleur et forme :SolidMasse moléculaire :891.81Antitumor agent-76
CAS :<p>Antitumor agent-76 is a water-soluble, orally active, rapid-release prodrug of Triptolide that exhibits anticancer effects.</p>Formule :C28H36ClNO10Couleur et forme :SolidMasse moléculaire :582.04IRAK4-IN-11
<p>IRAK4-IN-11 (compound 6) is a potent inhibitor of IRAK4 with an IC 50 of 0.008 μM. IRAK4-IN-11 exhibits cell pIRAK4 potencies with an IC 50 of 0.19 μM [1].</p>Formule :C16H19N7OCouleur et forme :SolidMasse moléculaire :325.37SARS-CoV-2 nsp14-IN-1
<p>SARS-CoV-2 nsp14-IN-1 inhibits Nsp14 Mtase with an IC50 of 0.061 μM, affecting multiple substrates.</p>Formule :C20H20N6O5SCouleur et forme :SolidMasse moléculaire :456.48β-Secretase Inhibitor III
<p>β-Secretase Inhibitor III is a highly selective inhibitor of BACE1 with a Ki value of 0.13 nM.</p>Formule :C20H20F2N4O3SCouleur et forme :SolidMasse moléculaire :434.46Anticancer agent 64
CAS :<p>Anticancer agent 64 (5m) induces apoptosis, has IC50 2.4μM in CCRF-CEM, activates caspases, cleaves PARP, affects mitochondria.</p>Formule :C31H46N2O2SCouleur et forme :SolidMasse moléculaire :510.77LRRK2-IN-6
<p>LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).</p>Formule :C23H24F2N4O2SCouleur et forme :SolidMasse moléculaire :458.52nAChR antagonist 1
CAS :<p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>Formule :C19H22N4O2Couleur et forme :SolidMasse moléculaire :338.4MSK-195
CAS :<p>MSK-195 is an effective TRPV1 agonist.</p>Formule :C28H40N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.63AA 497 (Free Base)
CAS :<p>AA 497, a beta-2 agonist, causes relaxation and suppresses Ca spike frequency.</p>Formule :C14H21NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :251.32SCP1-IN-1
CAS :<p>SCP1-IN-1 (SH T-62) is a potent inhibitor of SCP1, promoting REST degradation and potentially aiding glioblastoma research.</p>Formule :C20H19F3N2O7S2Degré de pureté :99.53%Couleur et forme :SoildMasse moléculaire :520.5EGFR/HER2-IN-8
<p>EGFR/HER2-IN-8 inhibits EGFR, HER2, DHFR (IC50: 0.45, 0.244, 5.669 μM); useful in cancer research, safe and selective.</p>Formule :C16H16N4O2SCouleur et forme :SolidMasse moléculaire :328.39Antitumor agent-51
<p>Antitumor agent-51 targets osteosarcoma with 21.9 nM IC50, high selectivity, and low toxicity.</p>Formule :C23H25N5O2SCouleur et forme :SolidMasse moléculaire :435.54DNA crosslinker 1 dihydrochloride
CAS :<p>DNA Crosslinker 1 binds DNA minor groove with 1.1°C affinity increase; used in cancer research.</p>Formule :C15H22Cl2N8OCouleur et forme :SolidMasse moléculaire :401.29c(phg-isoDGR-(NMe)k)
CAS :<p>c (phg-isoDGR- (NMe) k) is a selective and effective α5β1-integrin ligand with IC50 of 2.9 nM.</p>Formule :C27H41N9O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.67QCA570
CAS :<p>QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 Protein).</p>Formule :C39H33N7O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :695.79LY 215840
CAS :<p>5-HT2/5-HT7 receptor antagonist</p>Formule :C24H33N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.54Beclabuvir
CAS :<p>Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.</p>Formule :C36H45N5O5SDegré de pureté :99.87% - 99.93%Couleur et forme :SolidMasse moléculaire :659.84ALK5-IN-7
CAS :<p>ALK5-IN-7 inhibits ALK5, useful in TGF-β disease research like cancer, fibrosis, and autoimmune disorders. See WO2021129621A1.</p>Formule :C26H28N4O3SCouleur et forme :SolidMasse moléculaire :476.59Antibacterial agent 76
<p>Antibacterial agent 76 (compound 9) is a potent antibacterial agent.</p>Formule :C23H27N3O2SCouleur et forme :SolidMasse moléculaire :409.54
