Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.838 produits)
- Apoptose(6.316 produits)
- Cycle cellulaire/point de contrôle(4.881 produits)
- Chromatine/Épigénétique(2.615 produits)
- Signalisation du cytosquelette(1.570 produits)
- Altération de l'ADN/réparation de l'ADN(2.868 produits)
- Endocrinologie/Hormones(3.753 produits)
- Enzyme(3.673 produits)
- GPCR/G-Protéine(9.023 produits)
- Immunologie et Inflammation(3.903 produits)
- Virus de la grippe(300 produits)
- Signalisation JAK/STAT(415 produits)
- Signalisation MAPK(1.258 produits)
- Transporteur membranaire/Canal ionique(3.159 produits)
- Métabolisme(10.130 produits)
- Microbiologie/Virologie(7.618 produits)
- Neuroscience(10.516 produits)
- Autres inhibiteurs(35.844 produits)
- Oxydation-Réduction(40 produits)
- Signalisation PI3K/Akt/mTOR(1.431 produits)
- Protéases/Protéasome(1.688 produits)
- Cellules souche et Dérivés(729 produits)
- Tyrosine Kinase/Adaptateurs(1.983 produits)
- Ubiquitination(1.727 produits)
Affichez 16 plus de sous-catégories
66513 produits trouvés pour "Inhibiteurs"
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AP5
CAS :AP5: GPR40 agonist, positive allosteric modulator; rat hIP1 EC50: 0.49 nM.Formule :C28H28FNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.52CXN37378
CAS :CXN37378, aka NAP, is a potent MOR-selective antagonist with no official name yet, termed per MedKoo Nomenclature.Formule :C27H31N3O4Couleur et forme :SolidMasse moléculaire :461.55nNOS-IN-25
CAS :nNOS-IN-25 is an effective, selective, and cell-permeable inhibitor of neuronal nitric oxide synthase.Formule :C21H22N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :330.43A25822B
CAS :A25822B is an antifungal agent.Formule :C28H45NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.66Npc 12626
CAS :Npc 12626 is a N-methyl-D-aspartate receptor antagonist; NPC 17742, the (2R,4R,5S)-isomer, is the most potent isomer in the mixture NPC 12626.Formule :C11H22NO5PCouleur et forme :SolidMasse moléculaire :279.27Atiratecan
CAS :Atiratecan (TP300), a CH0793076-based camptothecin prodrug, combats BCRP+/- tumors; doesn't affect AChE.Formule :C31H34N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.64PTP1B-IN-18
PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 35.2 μM).PTP1B-IN-18 can be used to study type 2 diabetes.Formule :C26H19N3O4SCouleur et forme :SolidMasse moléculaire :469.51Rubropunctatin
CAS :Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.Formule :C21H23NO4Couleur et forme :SolidMasse moléculaire :353.41Domitroban
CAS :Domitroban, also known as S-145, is a thromboxane (Tx) A2-receptor antagonist with partial agonistic activity in vascular smooth muscle.Formule :C20H27NO4SCouleur et forme :SolidMasse moléculaire :377.5CEase-IN-1
CEase-IN-1 (A1H3), potent CEase inhibitor, IC50 0.36μM, for hypercholesterolemia study.Formule :C13H15F3N2O2Couleur et forme :SolidMasse moléculaire :288.27Flurdihydroergotamine
CAS :Flurdihydroergotamine, a serotonin 5HT1 receptor agonist, is used as an antimigraine drug.Formule :C34H36F3N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :651.68E7090 succinate
CAS :E7090 succinate inhibits FGFR1, FGFR2, and FGFR3 with IC50: 0.71, 0.50, 1.2 nM; less so FGFR4 at 120 nM.Formule :C76H92N10O24Couleur et forme :SolidMasse moléculaire :1529.60Cryptopleurine
CAS :Cryptopleurine is an inhibitor of gene products associated with cell proliferation, survival, invasion and angiogenesis. It acts by targeting the NF-κB pathway.Formule :C24H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48Trypanothione synthetase-IN-4
Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).Formule :C29H52INO2Couleur et forme :SolidMasse moléculaire :573.63COTC
CAS :COTC is an anticancer bacterial metabolite; inhibits glyoxalase with GSH, halts HeLa cell growth, and fights tumor in Ehrlich murine model.Formule :C11H14O6Couleur et forme :SolidMasse moléculaire :242.23STAT3-IN-8
CAS :"STAT3-IN-8 (compound H172) is a potent inhibitor of STAT3 with potential applications in cancer research [1]."Formule :C19H7F7N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.26Ribocil-C R enantiomer
Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor.Formule :C21H21N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.5Geissoschizoline
CAS :Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.Formule :C19H26N2OCouleur et forme :SolidMasse moléculaire :298.42PARL-IN-1
PARL-IN-1: Strong PARL blocker, IC50 28 nM, boosts PINK1/Parkin mitophagy.Formule :C40H58N6O7Couleur et forme :SolidMasse moléculaire :734.92Antitrypanosomal agent 6
Compound 18a: potent vs. T. brucei (IC50: 0.47 μM), >2x efficacy compared to Nifurtimox, good ADME, binds AT-rich DNA.Formule :C22H29Cl2N5OCouleur et forme :SolidMasse moléculaire :450.4MEK4 inhibitor-2
CAS :MEK4 Inhibitor-2, a novel MEK4 inhibitor, demonstrates efficacy against pancreatic adenocarcinoma, exhibiting an IC50 value of 83 nM.Formule :C20H15FN4O3SCouleur et forme :SolidMasse moléculaire :410.42Zalunfiban dihydrochloride
Zalunfiban (RUC-4) is a potent αIIbβ3 platelet antagonist, IC50 45 nM, used in myocardial infarction research.Formule :C16H20Cl2N8O2SCouleur et forme :SolidMasse moléculaire :459.35AFP-07
CAS :AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor.Formule :C22H29F2NaO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.45PF-06648671
CAS :PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.Formule :C25H23ClF4N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.92HP590
CAS :HP590: potent oral STAT3 inhibitor, IC50=27.8 nM, blocks ATP, IC50=24.7 nM, hinders gastric cancer growth, triggers cell death.Formule :C29H24F6N4O3Couleur et forme :SolidMasse moléculaire :590.52SGLT1/2-IN-1
CAS :SGLT1/2-IN-1 is a dual SGLT1/SGLT2 inhibitor.Formule :C25H28O8Couleur et forme :SolidMasse moléculaire :456.48Antibacterial agent 81
CAS :Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.Formule :C33H28N2O8Couleur et forme :SolidMasse moléculaire :580.58P-gp modulator 2
P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic P-glycoprotein (P-gp) modulator.Formule :C22H20BrN3O4Couleur et forme :SolidMasse moléculaire :470.32Colistin adjuvant-1
Colistin adjuvant-1, inhibits NF-κB (IC50: 0.209 μM), boosts mucin against gram-negative bacteria.Formule :C16H7F9N2OCouleur et forme :SolidMasse moléculaire :414.23MSK-195
CAS :MSK-195 is an effective TRPV1 agonist.Formule :C28H40N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.63XY153
XY153 (8l) is a BD2 selective BET inhibitor targeting BRD4, 3 & 2 with IC50s: 0.79, 5.31 & 5.09 nM, useful in acute myeloid leukemia & cancer research.Formule :C33H34FN3O4Couleur et forme :SolidMasse moléculaire :555.64HIV-1 inhibitor-17
HIV-1 inhibitor-18 blocks HIV-1 capsid, acts on NL4-3 strain (EC50: 2.57 μM), has low cytotoxicity (MT-4 CC50: >8.55).Formule :C32H32N4O5SCouleur et forme :SolidMasse moléculaire :584.69CBP/p300-IN-18
CBP/p300-IN-18 (compound 8) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.056 μM) and LK2 H3K27 (IC50: 0.46 μM).Formule :C25H27FN4O3Couleur et forme :SolidMasse moléculaire :450.51Rezatapopt
CAS :Rezatapopt (PC14586) is a p53 reactivator with antitumor activity for the study of locally advanced or metastatic solid tumors.Formule :C28H31F4N5O2Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :545.57Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Formule :C23H22BrN3O5Couleur et forme :SolidMasse moléculaire :500.34NA 0346
CAS :NA 0346 is a derivative of SF 2370 that shows long lasting antihypertensive action as well as potent protein kinases inhibitory activity.Formule :C26H22N4O3Couleur et forme :SolidMasse moléculaire :438.48PSMA-1007
CAS :PSMA-1007 is a novel Glu-Ureido-type prostate-specific membrane antigen (PSMA) inhibitor.Formule :C49H55FN8O16Couleur et forme :SolidMasse moléculaire :1030.01GSK3739936
CAS :GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.Formule :C34H43FN2O4Couleur et forme :SolidMasse moléculaire :562.71Mimocine
CAS :Mimosine, a plant amino acid, is known to act as a normoxic inducer of hypoxia-inducible factor (HIF).Formule :C15H14N2O5Couleur et forme :SolidMasse moléculaire :302.28ONO-AE1-259 lysine
CAS :ONO-AE1-259 is a highly selective agonist of prostaglandin e2 receptor (ep2)Formule :C28H49ClN2O6Couleur et forme :SolidMasse moléculaire :545.15[D-Leu-4]-OB3
CAS :[D-Leu-4]-OB3 suppresses the expression of genes associated with inflammation, proliferation, and metastasis, as well as the expression of PD-L1.Formule :C29H50N8O12SCouleur et forme :SolidMasse moléculaire :734.82BAY-364
CAS :BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+Formule :C23H19N3O4Couleur et forme :SolidMasse moléculaire :401.41ADP-2341
ADP-2341 is a soluble analog of FiVe1.Formule :C24H29Cl2N5O3Couleur et forme :SolidMasse moléculaire :506.43MtTMPK-IN-3
CAS :MtTMPK-IN-3 inhibits Mycobacterium tuberculosis kinase with IC50 0.12μM, MIC 12.5μM on Mtb, cytotoxic EC50 12.5μM on MRC-5 cells.Formule :C23H23Cl2N3O3Couleur et forme :SolidMasse moléculaire :460.35(-)-15-Deoxyspergualin
CAS :(-)-15-Deoxyspergualin is a potent antitumor agent that demonstrates significant inhibition against mouse leukemia L-1210.Formule :C17H37N7O3Couleur et forme :SolidMasse moléculaire :387.52HDAC-IN-37
HDAC-IN-37 inhibits HDACs 1, 3, 8, & 6, induces histone acetylation, halts G1 to S phase, and triggers early apoptosis.Formule :C23H24ClN7OCouleur et forme :SolidMasse moléculaire :449.94IDO2-IN-1
CAS :IDO2-IN-1: potent oral IDO2 inhibitor, IC50 = 112 nM, for inflammatory autoimmunity research.Formule :C21H21BrN10O3Couleur et forme :SolidMasse moléculaire :541.36CCR1 antagonist 11 hydrochloride
Oral CCR1 antagonist A1B1 targets h/m/rCCR1 (IC50: 0.03/0.58/0.32 μM), potential for treating inflammatory diseases.Couleur et forme :SolidCXCR4 modulator-1
CAS :CXCR4 modulator-1 (ZINC72372983) is potent (EC50=100nM) with uses in anti-inflammatory, anticancer, and anti-HIV research.Formule :C23H27N5O2Couleur et forme :SolidMasse moléculaire :405.49Oncopterin
CAS :Oncopterin is found in urine from patients with solid and blood cancers.Formule :C12H18N6O3Couleur et forme :SolidMasse moléculaire :294.31SC13
CAS :SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.Formule :C26H30N2O5Couleur et forme :SolidMasse moléculaire :450.53Sucistil
Sucistil is an active biochemical. hemoglobin sucistil (bovine) is an oxygen carrier [1].Formule :C9H15NO4SCouleur et forme :SolidMasse moléculaire :233.28MA242 free base
CAS :MA242 free base is a dual MDM2/NFAT1 inhibitor that triggers apoptosis in pancreatic cancer cells.Formule :C24H20ClN3O3SCouleur et forme :SolidMasse moléculaire :465.95MDL-100240
CAS :MDL-100240 inhibits ACE/neprilysin, effective against hypertension-induced heart/vascular changes.Formule :C26H28N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :480.58TLR7/8 agonist 7
CAS :TLR7/8 agonist 7 activates immune cells, useful in ISAC synthesis and immunity research.Formule :C26H37N7O2Couleur et forme :SolidMasse moléculaire :479.62Mt KARI-IN-1
Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.Formule :C14H11N5O4S2Couleur et forme :SolidMasse moléculaire :377.4Emtricitabine triphosphate
CAS :Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.Formule :C8H13FN3O12P3SCouleur et forme :SolidMasse moléculaire :487.19EP4 receptor antagonist 2
CAS :EP4 receptor antagonist 2 (compound 2-13) is a potent agonist of the EP4 receptor (IC50: 7.8 nM) and has antitumour effects.Formule :C27H29N3O5Couleur et forme :SolidMasse moléculaire :475.54Everafenib
Everafenib: potent BRAF inhibitor, crosses blood-brain barrier, hinders MAPK, effective on V600EBRAF cells, outperforms other drugs in trials.Formule :C20H23ClFN5O2S2Couleur et forme :SolidMasse moléculaire :484.01trans-RdRP-IN-5
Trans-RdRP-IN-5 is a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), with applications in influenza virus research.Formule :C23H21N3O5Couleur et forme :SolidMasse moléculaire :419.43BAY-899
CAS :BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.Formule :C25H19F2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.45A1-Phytoprostane-I
CAS :A1-Phytoprostane-I: cyclopentenone from α-linolenic acid in plants, induces gene expression & increases phytoalexin synthesis.Formule :C18H28O4Couleur et forme :SolidMasse moléculaire :308.41MAO-B-IN-7
MAO-B-IN-7 inhibits MAO-B/AChE, crossing the blood-brain barrier; IC50: 41/87 nM (h/eel AChE), 0.3 μM (MAO-B). Reduces oxidative stress and neuroinflammation.Formule :C25H31NO4Couleur et forme :SolidMasse moléculaire :409.52BMS-554417
CAS :BMS-554417 inhibits IGF-IR/insulin receptors, curbing cell proliferation and tumor growth, with IC50 values of 120 nm–>8.5 μmol/L.Formule :C28H30ClN7O2Couleur et forme :SolidMasse moléculaire :532.04Topoisomerase I/II inhibitor 2
Compound 1a inhibits Topoisomerase I/II, shrinks mouse liver tumors, IC50: 6.83/9.82 μM for LM9/Huh7 cells.Formule :C19H16N2O4Couleur et forme :SolidMasse moléculaire :336.34MEIS-IN-2
MEIS-IN-2 is an inhibitor of MEIS1. MEIS-IN-2 can be used in studies of cardiac regeneration and haematopoietic stem cell (HSC) regulation.Formule :C23H21ClN2O4Couleur et forme :SolidMasse moléculaire :424.88Antiangiogenic agent 2
Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.
Formule :C26H26FN3O4Couleur et forme :SolidMasse moléculaire :463.5SG3199
CAS :SG3199, a PBD dimer, binds DNA's minor groove, forms covalent cross-links, and is cytotoxic to various human cancer cells.Formule :C33H36N4O6Couleur et forme :SolidMasse moléculaire :584.66PRMT5-IN-21
PRMT5-IN-21 (compound 1) is a potent inhibitor of cyclonucleoside PRMT5.Formule :C18H18F2N6O3Couleur et forme :SolidMasse moléculaire :404.37hDDAH-1-IN-2 sulfate
hDDAH-1-IN-2: selective oral hDDAH-1 inhibitor with low cell toxicity.Formule :C8H24N4O10S2Couleur et forme :SolidMasse moléculaire :400.43GLS1 Inhibitor-6
GLS1 Inhibitor-6: IC50=68nM, 220x more selective for GLS2, has anti-tumor and pro-apoptosis effects.Formule :C37H52N6O3SCouleur et forme :SolidMasse moléculaire :660.91SR 33805 oxalate
CAS :Ca2+ channel antagonistFormule :C34H42N2O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :654.77GSK-1264
CAS :GSK-1264: allosteric HIV integrase inhibitor, halts viral replication & abnormal protein multimerization.Formule :C26H28FNO5Couleur et forme :SolidMasse moléculaire :453.5YW3-56
CAS :YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.Formule :C27H32ClN5O2Couleur et forme :SolidMasse moléculaire :494.03Cdc7-IN-11
CAS :Cdc7-IN-11 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in the study of proliferative diseases.Formule :C20H22F2N4O2SCouleur et forme :SolidMasse moléculaire :420.48CY208-243 Mandelate
CAS :CY208-243 is a D1 agonist boosting memory in T-maze, enhances adenylate cyclase (EC50=125nM), and alters monkey electroretinogram.Formule :C27H26N2O3Couleur et forme :SolidMasse moléculaire :426.52SM-433 hydrochloride
SM-433 hydrochloride, a Smac mimetic & IAP inhibitor, binds XIAP BIR3; potent IC50 <1 μM. (Patent WO2008128171A2)Formule :C32H44ClN5O4Couleur et forme :SolidMasse moléculaire :598.18KR-67607
CAS :KR-67607, or NTX-101, is a novel 11β-HSD1 inhibitor that protects against eye injury by reducing cortisol and preserving eye structures.Formule :C24H29Cl2F3N4O4SCouleur et forme :SolidMasse moléculaire :597.48EB-0150
EB-0150 inhibits ER α-Glu I/II (IC50: 0.73/0.0337 μM), is an N-substituted valerian with antiviral effects, and has drug discovery potential.Formule :C19H30N6O7Couleur et forme :SolidMasse moléculaire :454.48Idraparinux Na
CAS :Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa InhibitorFormule :C38H55Na9O49S7Couleur et forme :SolidMasse moléculaire :1727.14EP-7041 HCl
CAS :EP-7041 is a novel, potent, and selective Factor XIa inhibitor.Formule :C19H27ClN4O4Couleur et forme :SolidMasse moléculaire :410.89PF-06462894
CAS :PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.Formule :C18H23N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.39GPBAR1-IN-3
CAS :GPBAR1-IN-3 (Compound 14) is both a selective agonist for GPBAR1, with an EC50 value of 0.17 μM, and an antagonist for CysLT1R [1].Formule :C21H23NO2Couleur et forme :SolidMasse moléculaire :321.4115-keto-Prostaglandin E2
CAS :15-keto-Prostaglandin E2, an endogenous metabolite, inhibits STAT3 activation through binding to Cys259 and regulates breast cancer cell growth and progression.Formule :C20H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.45Cyclophilin inhibitor 1
CAS :Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.Formule :C31H39N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.67SR121566A
CAS :SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).Formule :C20H25N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.51VU6005806
CAS :VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.Formule :C17H16F3N7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.411,9-Dideoxyforskolin
CAS :The compound is an inactive analog of forskolin(an adenylyl cyclase activator).Formule :C22H34O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.5p38 MAPK-IN-3
Compound 2c is a potent p38α MAPK inhibitor with antitumor effects, enhancing apoptosis and ROS.Formule :C22H17BrO2Couleur et forme :SolidMasse moléculaire :393.27J-104132
CAS :J-104132: potent human ETA/B antagonist; Ki: ETA=0.034nM, ETB=0.104nM; prevents ET-1 effects, ED50 i.v.=0.045mg/kg, p.o.=0.35mg/kg.Formule :C31H33NO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.60Antibacterial agent 66
Compound 6q, a trifluoromethylpyridine oxadiazole, targets Xanthomonas oryzae with EC50 of 7.2 μg/mL.Formule :C17H10ClF6N3O2SCouleur et forme :SolidMasse moléculaire :469.79Aurora/LIM kinase-IN-1
Aurora/LIM kinase-IN-1 (Compound F114) is a dual inhibitor targeting aurora and lim kinases, potentially useful in GBM cancer treatment efforts.Formule :C16H20N6OCouleur et forme :SolidMasse moléculaire :312.37BACE1-IN-8
BACE1-IN-8 is a potent inhibitor of BACE1 (β-site APP lyase 1) (IC50: 3.9 μM).Formule :C29H45N5O7Couleur et forme :SolidMasse moléculaire :575.7Calphostin B
CAS :Calphostins, PKC inhibitors from Cladosporium fungus, include A, B, C, D, I; C is most potent.Formule :C37H34O11Couleur et forme :SolidMasse moléculaire :654.66LRRK2-IN-6
LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).Formule :C23H24F2N4O2SCouleur et forme :SolidMasse moléculaire :458.52MS117
MS117 is a first-in-class and cell-active irreversible covalent inhibitor of protein arginine methyltransferase 6 (PRMT6) (IC50 = 18 nM) [1].Formule :C17H22N4OCouleur et forme :SolidMasse moléculaire :298.38QTX125 TFA
QTX125 TFA: Potent, selective HDAC6 inhibitor with antitumor effects.Formule :C25H20F3N3O7Couleur et forme :SolidMasse moléculaire :531.44Protopine hydrochloride
CAS :Protopine inhibits thromboxane, lowers intracellular calcium, and reduces cell adhesion by altering adhesive factors.Formule :C20H20ClNO5Degré de pureté :98%Couleur et forme :Prisms From Alc SolidMasse moléculaire :389.83Asimicin
CAS :Asimicin is a effective complex I inhibitor.Formule :C37H66O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :622.92EBOV-GP-IN-1
EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).Formule :C25H40ClN3O2Couleur et forme :SolidMasse moléculaire :450.06CXCR2 antagonist 7
CXCR2 antagonist 7 is a powerful blocker with IC50s: 0.044 μM for binding, 0.66 μM for calcium mobilization.Formule :C14H14F2N6OSCouleur et forme :SolidMasse moléculaire :352.36SARS-CoV-2 nsp3-IN-1
Compound 15c selectively inhibits SARS-CoV-2 nsp3 Mac1 with IC50 of 6.1 μM.Formule :C17H15N5O2Couleur et forme :SolidMasse moléculaire :321.33LJ-4517
LJ-4517 is an effective A2AAR antagonist (Ki=18.3 nM). LJ-4517 can effectively replace the binding of [3H] ZM241385 at WT A2AAR.Formule :C19H21N5O3SCouleur et forme :SolidMasse moléculaire :399.47HIV-1 inhibitor-13
HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).Formule :C30H32N6O3Couleur et forme :SolidMasse moléculaire :524.61EGFR-IN-35
CAS :EGFR-IN-35, an acrylamide-based EGFR inhibitor, shows promise for EGFR mutation-related cancers like NSCLC.Formule :C25H24ClN7O2Couleur et forme :SolidMasse moléculaire :489.96Glutaminyl cyclases-IN-1
Glutaminyl cyclase inhibitor IsoQC-IN-1: IC50=12 nM for QC, 73 nM for isoQC; blocks CD47/SIRPα; boosts THP-1, U937 macrophage phagocytosis.Formule :C25H30N6O2SCouleur et forme :SolidMasse moléculaire :478.61Fonsartan free acid
CAS :Fonsartan: Angiotensin receptor blocker, halts angiotensin II effects on rat vascular cells.Formule :C26H32N4O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :544.69M826
M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity inFormule :C28H45N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.7BM635 mesylate (1493762-74-5 free base)
BM635 mesylate is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).Formule :C26H33FN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :488.61MCTR2
CAS :MCTR2, synthesized from DHA in macrophages, aids in tissue repair and reduces inflammation by promoting eicosanoid PGD2 and PGF2α decrease.Formule :C27H40N2O6SCouleur et forme :SolidMasse moléculaire :520.68RN941
CAS :RN941 is a highly potent Bruton's tyrosine kinase (BTK) inhibitor.Formule :C34H34FN7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :639.68Ro-24-4736
CAS :Ro 24-4736 is an effective and selective platelet-activating factor antagonist.Formule :C31H20ClN5OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :546.04Antibacterial agent 76
Antibacterial agent 76 (compound 9) is a potent antibacterial agent.Formule :C23H27N3O2SCouleur et forme :SolidMasse moléculaire :409.54Ivaltinostat formic
Ivaltinostat (CG-200745) is an oral panHDAC inhibitor, inducing apoptosis and enhancing cancer drug sensitivity.Formule :C25H35N3O6Couleur et forme :SolidMasse moléculaire :473.56Isoleucyl tRNA synthetase-IN-1
CAS :Isoleucyl tRNA synthetase-IN-1 is a selective and potent inhibitor (Ki: 88 nM) that targets isoleucyl tRNA synthetase (IleRS).Formule :C23H35N5O7SCouleur et forme :SolidMasse moléculaire :525.62Aniline-MPB-amino-C3-PBD
CAS :Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised of the non-alkylating group. It is a sequence-selective DNA minor-groove binding agent.Formule :C42H46N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :758.86LASSBio-1632
LASSBio-1632: Novel anti-asthmatic, blocks PDE4A/D, reduces AHR & lung TNF-α, crosses BBB.Formule :C18H20N2O6SCouleur et forme :SolidMasse moléculaire :392.43EGFR-IN-18
EGFR-IN-18 strongly inhibits L858R/T790M/C797S mutant EGFR (4.9 nM) and also targets wild-type EGFR (47 nM).Formule :C33H28N6O3SCouleur et forme :SolidMasse moléculaire :588.68GENZ-882706
CAS :GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor.Formule :C26H25N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.51EGFR/HER2-IN-4
EGFR/HER2-IN-4: oral, irreversible dual EGFR inhibitor (IC50: 0.6 nM), targets L858R/T790M mutations, potent anti-lung cancer effects in vivo.Couleur et forme :SolidA 74273
CAS :A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition.Formule :C44H74N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :787.08NTU281
CAS :NTU281 inhibits transglutaminase-2, lowers creatinine in diabetic rats, reduces proteinuria, and fights glomerulosclerosis.Formule :C25H31N2O6SCouleur et forme :SolidMasse moléculaire :487.59CBP/p300-IN-2
CAS :CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc).Formule :C27H29F2N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.56Teslexivir
CAS :Teslexivir is a topical antiviral agent that is an effective and selective inhibitor of the interaction between two essential viral proteins, E1 and E2.Formule :C35H36BrN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :642.58RF9 hydrochloride
RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist that acts on hNPFF1R (Ki: 58 nM) and hNPFF2R (Ki: 7 nM).Formule :C26H39ClN6O3Couleur et forme :SolidMasse moléculaire :519.08SGK1-IN-3
CAS :SGK1-IN-3: Potent oral inhibitor of SGK1, may target osteoarthritis.Formule :C23H20Cl2N6O3SCouleur et forme :SolidMasse moléculaire :531.414SARS-CoV-2-IN-8
SARS-CoV-2-IN-8 is a major protease inhibitor of SARS-CoV-2 (IC50: 0.75 μM).Formule :C35H38N6O3Couleur et forme :SolidMasse moléculaire :590.71PF-06380101
CAS :PF-06380101, a potent auristatin analog and Dolastatin 10 derivative, shows strong anti-tumor activity and unique ADME attributes.Formule :C39H62N6O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :743.01Prohibitin ligand 1
Compound 22i, a prohibitin ligand, protects the heart at nanomolar levels by inducing STAT3 phosphorylation.Formule :C20H22N2OCouleur et forme :SolidMasse moléculaire :306.4Mibefradil
CAS :Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).Formule :C29H38FN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.63AMG-369
CAS :AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.Formule :C26H22FN3O2SDegré de pureté :98.04% - 98.92%Couleur et forme :SolidMasse moléculaire :459.54HDAC6/HSP90-IN-2
HDAC6/HSP90-IN-2, a cancer research chemical, inhibits HDAC6 & Hsp90 with IC50s of 105.7 & 61 nM.Formule :C19H22N2O5Couleur et forme :SolidMasse moléculaire :358.39Dexnebivolol
CAS :Dexnebivolol (R67138), a ß-adrenergic antagonist, is Nebivolol's enantiomer with β1 blocking and vasodilation properties.Formule :C22H25F2NO4Couleur et forme :SolidMasse moléculaire :405.43Difeterol
CAS :Difeterol is a biochemical.Formule :C25H29NO2Couleur et forme :SolidMasse moléculaire :375.50ROS1-IN-1
ROS1-IN-1, a potent ROS1 kinase inhibitor, has an IC50 of 0.097 μM.Formule :C17H15ClN6SCouleur et forme :SolidMasse moléculaire :370.86Carbonic anhydrase inhibitor 10
CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.Formule :C14H17N5O3SCouleur et forme :SolidMasse moléculaire :335.38CHK1-IN-4
CAS :CHK1-IN-4 is a potent inhibitor of checkpoint kinase 1 (chk1) and potently inhibits chk1 phosphorylation in the tumor cells with anti-tumor activity.Formule :C18H18BrN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.29Tyk2-IN-3
CAS :Tyk2-IN-3 is an inhibitor of Tyk2 pseudokinase (IC50: 485 nM).Formule :C25H24N6O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.63SHR902275
CAS :SHR902275: potent RAF inhibitor, hits RAS mutations, oral use. cRAF IC50=1.6 nM, bRAFwt IC50=10 nM, bRAFV600E IC50=5.7 nM, hinders cell growth.Formule :C26H23F3N4O4Couleur et forme :SolidMasse moléculaire :512.48SCP1-IN-1
CAS :SCP1-IN-1 (SH T-62) is a potent inhibitor of SCP1, promoting REST degradation and potentially aiding glioblastoma research.Formule :C20H19F3N2O7S2Degré de pureté :99.53%Couleur et forme :SoildMasse moléculaire :520.5Ref: TM-T60077
1mg49,00€5mg104,00€1mL*10mM (DMSO)119,00€10mg169,00€25mg311,00€50mg472,00€100mg707,00€MDL-27788
CAS :MDL-27788 is a tricyclic inhibitor.Formule :C24H26N2O5SCouleur et forme :SolidMasse moléculaire :454.54DGY-08-097
CAS :DGY-08-097: potent HCV NS3 degrader, low resistance risk, strong inhibition in cells, DC50 of 50nM at 4h.Formule :C60H76N10O14Couleur et forme :SolidMasse moléculaire :1161.3Tubulin inhibitor 13
CAS :Tubulin inhibitor 13 (E27), IC50 16.1 μM, blocks tubulin polymerization, cancer cell migration, and invasion, induces apoptosis.Formule :C25H21N3O4Couleur et forme :SolidMasse moléculaire :427.45Tubulin inhibitor 22
Compound 4c: Strong tubulin inhibitor with anti-cancer & anti-angiogenic effects; halts MGC-803 cells in G2/M, triggers Caspase-mediated apoptosis.Formule :C20H17BrFNO4Couleur et forme :SolidMasse moléculaire :434.26CDK5-IN-2
CAS :CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor that acts on CDK5/p25 (IC50: 0.2 nM) and CDK2/CycA (IC50: 23 nM).Formule :C29H28FN5OCouleur et forme :SolidMasse moléculaire :481.56ZD6021
CAS :ZD6021 is an antagonist of neurokinin 1 receptor.Formule :C35H35Cl2N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :632.64Mf 268
CAS :Mf 268 is a pseudo-reversible carbamate-type inhibitor which interacts with the catalytic and regulatory anionic site of the enzyme.Formule :C28H46N4O3Couleur et forme :SolidMasse moléculaire :486.69FXIa-IN-10
FXIa-IN-10 is a potent, orally bioavailable inhibitor of Activator XI (FXIa) (Ki: 0.17 nM).Formule :C23H18Cl2F3N9O2Couleur et forme :SolidMasse moléculaire :580.35BMT-052
CAS :BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).Formule :C30H17D9F4N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :635.61Ascofuranone
CAS :Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODHFormule :C23H29ClO5Couleur et forme :SolidMasse moléculaire :420.93BRD1991
CAS :BRD1991 is a chemical compound that specifically disrupts the interaction between Beclin 1 and Bcl-2, thereby inducing autophagy.Formule :C33H35Cl2N3O4Couleur et forme :SolidMasse moléculaire :608.55AZD-4121
CAS :AZD-4121 is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.Formule :C36H39F2N3O7SCouleur et forme :SolidMasse moléculaire :695.77S100A2-p53-IN-1
CAS :S100A2-p53-IN-1 inhibits S100A2-p53 in pancreatic cancer, stunting MiaPaCa-2 cell growth at 1.2-3.4 μM.Formule :C20H20F6N2O4SCouleur et forme :SolidMasse moléculaire :498.44Atorvastatin 3-Deoxyhept-2E-Enoic Acid
CAS :Atorvastatin 3-Deoxyhept-2E-Enoic Acid, an impurity in Atorvastatin, lowers blood lipids as an HMG-CoA reductase inhibitor.Formule :C33H33FN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.62Vulolisib
CAS :Vulolisib inhibits PI3K (α: IC50 0.2nM, β: 168nM, γ: 90nM, δ: 49nM), taken orally with anti-cancer properties.Formule :C18H19F2N5O3SCouleur et forme :SolidMasse moléculaire :423.44Antimalarial agent 2
Antimalarial agent 2 is an orally active, novel antimalarial agent that exhibits rapid in vitro killing effects.Formule :C27H25N3O5Couleur et forme :SolidMasse moléculaire :471.5CDK1-IN-4
CDK1-IN-4 inhibits CDK1 (IC50: 44.52 nM), CDK2/CDK5 less potently, impacts cell cycle, used in cancer studies.Formule :C26H24ClN5SCouleur et forme :SolidMasse moléculaire :474.02Dyrk1A/α-synuclein-IN-1
Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual inhibitor of Dyrk1A (IC50: 177 nM) and α-synuclein aggregation (IC50: 10.5 μM).Formule :C20H21N5O3SCouleur et forme :SolidMasse moléculaire :411.48MDL-27088
CAS :MDL-27088 is an angiotensin-covering enzyme inhibitor.Formule :C25H28N2O5Couleur et forme :SolidMasse moléculaire :436.50JAK2/FLT3-IN-1 TFA
JAK2/FLT3-IN-1 (TFA), an oral JAK2/FLT3 inhibitor, shows anticancer properties; IC50: JAK2 (0.7 nM), FLT3 (4 nM), JAK1 (26 nM), JAK3 (39 nM).Formule :C27H35F4N7O3Couleur et forme :SolidMasse moléculaire :581.61FGFR-IN-6
CAS :FGFR-IN-6 (Compound 5) is an FGFR inhibitor.Formule :C23H22N6O3Couleur et forme :SolidMasse moléculaire :430.46Mibefradil dihydrochloride hydrate
CAS :Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.Formule :C29H42Cl2FN3O4Couleur et forme :SolidMasse moléculaire :586.57Ceclazepide
CAS :Ceclazepide is an antagonist of cholecystokinin receptor.Formule :C30H32N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.61Topo I/COX-2-IN-2
Compound W10 is a dual inhibitor of Topo I (IC50: 0.90μM) and COX-2 (IC50: 2.31μM), inducing cancer cell apoptosis via mitochondria.Formule :C24H25ClN4OCouleur et forme :SolidMasse moléculaire :420.93Raloxifene N-Oxide
CAS :Raloxifene N-Oxide is a Raloxifene oxidative degradation product.Formule :C28H27NO5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :489.58M-89 MLL inhibitor
CAS :M-89, a potent Menin-MLL blocker: Kd 1.4 nM, IC50 25 nM for MV4;11 cells, 55 nM for MOLM-13, >100x selective over HL-60.Formule :C37H47N5O4SCouleur et forme :SolidMasse moléculaire :657.87Ambelline
CAS :Ambelline has antitumor activity.Formule :C18H21NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.36FW 34569
CAS :FW 34569, an enkephalin analog, boosts growth hormones and prolactin, reduces cortisol and LH; FSH stable.Formule :C30H43N5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :617.76SPR719
CAS :SPR719 is an inhibitor of gyrase B, has bactericidal activity.Formule :C21H25FN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.46HR-546
CAS :HR-546 is a prostaglandin E2 and prostaglandin F2alpha antagonist.Formule :C26H44O6Couleur et forme :SolidMasse moléculaire :452.62COX-2-IN-8
COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 μM) with a higher COX-2 selectivity than Celecoxib.Formule :C19H19N3O4S2Couleur et forme :SolidMasse moléculaire :417.5Diarylalkane derivative 1
CAS :Diarylalkane derivative 1 is used for the research of pancreatitis.Formule :C34H51NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :537.77LY 245769
CAS :LY 245769 is an inhibitor of leukotriene E4 (LTE4).Formule :C25H33F3N8OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.648(S),15(S)-DiHETE
CAS :8(S),15(S)-DiHETE, from 15(S)-HETE's oxidation by 15-LO, triggers eosinophil movement at 1.5 μM; it counteracts pain and LTB4 effects.Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47FY-56
FY-56: potent, selective LSD1/KDM1A inhibitor (IC50=42nM); differentiates MOLM-13/MV4-11 cells; promising for AML research.Formule :C23H19FN2O3Couleur et forme :SolidMasse moléculaire :390.41DMP-728 free base
CAS :DMP-728 free base is a highly potent and selective GPIIbDIIa antagonistFormule :C25H36N8O7Couleur et forme :SolidMasse moléculaire :560.60ALK5-IN-7
CAS :ALK5-IN-7 inhibits ALK5, useful in TGF-β disease research like cancer, fibrosis, and autoimmune disorders. See WO2021129621A1.Formule :C26H28N4O3SCouleur et forme :SolidMasse moléculaire :476.59NNC-11-1585
CAS :NNC-11-1585 is an M(1) and M(2) muscarinic acetylcholine receptor (mAChR) agonist.Formule :C18H19N3OSCouleur et forme :SolidMasse moléculaire :325.43FAPI-74
CAS :FAPI-74 is a PET (positron emission tomography) tracer involved in early FAPI-PET imaging.FAPI-74 can be used to study cancer tumors and degenerative diseases.
Formule :C36H49N9O8Couleur et forme :SolidMasse moléculaire :735.83hDHODH-IN-10
hDHODH-IN-10: selective oral inhibitor of hDHODH (IC50: 10.9 nM); blocks cancer cell growth, aids cancer research.Formule :C21H15ClF4N2O4Couleur et forme :SolidMasse moléculaire :470.8PPARγ agonist 1
PPARγ agonist 1 is a potent agonist of PPARγ that efficiently activates hPPARγ without causing full agonism, thereby avoiding adverse effects.Formule :C34H39NO3Couleur et forme :SolidMasse moléculaire :509.68Nomelidine
CAS :Nomelidine, the active N-demethylated metabolite of zimelidine, has been used as an antidepressant and analgesic.Formule :C15H15BrN2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :303.20BDZ-h
CAS :BDZ-h inhibits both closed/open states of all 4 homomeric & 2 GluA2R-complex AMPA receptors.Formule :C21H21N5O3SCouleur et forme :SolidMasse moléculaire :423.49AL-GDa62
AL-GDa62, a gastric cancer treatment lead, has EC50 of 3.2 μM (MCF10A-WT) and 2 μM (MCF10A-CDH1 -/-).Formule :C24H28FN3OCouleur et forme :SolidMasse moléculaire :393.5PRMT5-IN-18
CAS :PRMT5-IN-18 (Compound 002) is a potent inhibitor of PRMT5 and can be used in the study of PRMT5-mediated diseases, such as tumours.Formule :C32H42N4O4Couleur et forme :SolidMasse moléculaire :546.70LSD1/2-IN-3
LSD1/2-IN-3 selectively inhibits LSD1 (Ki 11 nM) over LSD2 (Ki 7 μM), and hinders tumor stem cell proliferation.Formule :C9H8BrF2NCouleur et forme :SolidMasse moléculaire :248.07FTO-IN-1 TFA
FTO-IN-1 TFA: FTO enzyme inhibitor, anti-obesity, IC50 < 1μM, potential cancer research tool.Formule :C20H17Cl2F3N4O4Couleur et forme :SolidMasse moléculaire :505.27LEO 134310
CAS :LEO 134310: Selective, non-steroidal GR agonist with 14 nM EC50, for topical skin disease treatment.Formule :C34H40N2O8Couleur et forme :SolidMasse moléculaire :604.69Multi-kinase-IN-1
CAS :Multi-kinase-IN-1, a powerful kinase inhibitor, exhibits antitumor properties by inducing cell apoptosis.Formule :C35H36F2N6O6SCouleur et forme :SolidMasse moléculaire :706.76Anti-MRSA agent 2
CAS :Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.Formule :C18H10Br2N2OCouleur et forme :SolidMasse moléculaire :430.09Inupadenant HCl
CAS :Inupadenant (EOS-850) is a selective A2a receptor antagonist, targeting immunosuppression in tumors.Formule :C25H27ClF2N8O4S2Couleur et forme :SolidMasse moléculaire :641.11Tauro-ω-muricholic acid sodium
Tauro-ω-muricholic acid sodium (TωMCA sodium) is an analogue of tauro-α-muricholic acid, a bile acid of hepatic origin.Formule :C26H44NNaO7SCouleur et forme :SolidMasse moléculaire :537.68SB 224289
CAS :SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.Formule :C32H32N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.62c(phg-isoDGR-(NMe)k)
CAS :c (phg-isoDGR- (NMe) k) is a selective and effective α5β1-integrin ligand with IC50 of 2.9 nM.Formule :C27H41N9O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.67MC2652
MC2652, a potent LSD1 inhibitor, suppresses leukemia (MV4-11, NB4) and impedes prostate cancer (LNCaP) cell growth.Formule :C22H20N2OCouleur et forme :SolidMasse moléculaire :328.41CARM1-IN-3 dihydrochloride
CARM1-IN-3 dihydrochloride (17b) is a potent CARM1 inhibitor (IC50: 0.07 μM) with selectivity over CARM3 (IC50 >25 μM).Formule :C24H34Cl2N4O2Couleur et forme :SolidMasse moléculaire :481.46KDOAM-25 trihydrochloride (2230731-99-2 free base)
KDOAM-25 trihydrochloride, a selective KDM5 inhibitor (IC50: 19-71 nM), boosts H3K4 methylation and hinders MM1S cell growth.Formule :C15H28Cl3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.77NLRP3-IN-4
NLRP3-IN-4 is an effective, oral NLRP3 inflammasome inhibitor with potent anti-inflammatory effects on colitis.Formule :C22H22N2O5Couleur et forme :SolidMasse moléculaire :394.42PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Formule :C33H33N3O4Couleur et forme :SolidMasse moléculaire :535.63Dazucorilant
CAS :Dazucorilant (CORT113176), a selective non-steroidal GR modulator, has high affinity with a K i <1 nM, useful for neurological research.Formule :C29H22F4N4O3SCouleur et forme :SolidMasse moléculaire :582.57
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