Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.523 produits)
- Apoptose(5.792 produits)
- Cycle cellulaire/point de contrôle(4.449 produits)
- Chromatine/Épigénétique(2.238 produits)
- Signalisation du cytosquelette(1.383 produits)
- Altération de l'ADN/réparation de l'ADN(2.825 produits)
- Endocrinologie/Hormones(3.507 produits)
- Enzyme(3.640 produits)
- GPCR/G-Protéine(8.333 produits)
- Immunologie et Inflammation(3.526 produits)
- Virus de la grippe(296 produits)
- Signalisation JAK/STAT(404 produits)
- Signalisation MAPK(1.202 produits)
- Transporteur membranaire/Canal ionique(2.790 produits)
- Métabolisme(9.448 produits)
- Microbiologie/Virologie(6.981 produits)
- Neuroscience(9.926 produits)
- Autres inhibiteurs(37.926 produits)
- Oxydation-Réduction(41 produits)
- Signalisation PI3K/Akt/mTOR(1.400 produits)
- Protéases/Protéasome(1.597 produits)
- Cellules souche et Dérivés(831 produits)
- Tyrosine Kinase/Adaptateurs(2.016 produits)
- Ubiquitination(1.650 produits)
Affichez 16 plus de sous-catégories
66641 produits trouvés pour "Inhibiteurs"
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PARP1-IN-5
<p>PARP1-IN-5 is a potent, selective, orally active, low-toxicity PARP-1 inhibitor with an IC50 value of 14.7 nM. PARP1-IN-5 can be used in cancer research.</p>Formule :C25H24N2O5SCouleur et forme :SolidMasse moléculaire :464.53α-Glucosidase-IN-18
<p>α-Glucosidase-IN-18 (7B) is an orally active inhibitor of α-glucosidase, displaying an IC 50 value of 3.96 μM.</p>Formule :C23H19NO2SCouleur et forme :SolidMasse moléculaire :373.47STAT3-IN-9
<p>STAT3-IN-9 hinders STAT3 at Tyr705, doesn't affect STAT1 Tyr701, induces apoptosis, and arrests cells in G2/M phase.</p>Formule :C22H21N3O4Couleur et forme :SolidMasse moléculaire :391.42FAK-IN-4
<p>FAK-IN-4 (Compound 7d) has anticancer activities that can induce cell apoptosis. FAK-IN-4 is potential inhibitor of FAK [1].</p>Formule :C20H22N4OCouleur et forme :SolidMasse moléculaire :334.41LY210073
CAS :<p>LY210073 is an antagonist of the Leukotriene B4 (LTB4) receptor (IC50: 6.2 nM).</p>Formule :C30H28O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :516.54MEK4 inhibitor-2
CAS :<p>MEK4 Inhibitor-2, a novel MEK4 inhibitor, demonstrates efficacy against pancreatic adenocarcinoma, exhibiting an IC50 value of 83 nM.</p>Formule :C20H15FN4O3SCouleur et forme :SolidMasse moléculaire :410.42cis-RdRP-IN-5
<p>Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.</p>Formule :C23H21N3O5Couleur et forme :SolidMasse moléculaire :419.43NS2B/NS3-IN-3
CAS :<p>NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .</p>Formule :C19H21N3O2Couleur et forme :SolidMasse moléculaire :323.39Sequoiaflavone
CAS :<p>Sequoiaflavone is a biflavone isolated from Ginkgo biloba.</p>Formule :C31H20O10Couleur et forme :SolidMasse moléculaire :552.48STING agonist-20
CAS :<p>STING agonist-20: potent, aids in XMT-2056 synthesis, used as a cancer vaccine adjuvant.</p>Formule :C36H39N11O8Couleur et forme :SolidMasse moléculaire :753.76PX-316
CAS :<p>PX-316: AKT inhibitor, reduces Akt activity by 78% in HT-29 xenografts, effective against MCF-7 and HT-29 cancers, well-tolerated intravenously.</p>Formule :C28H57O10PCouleur et forme :SolidMasse moléculaire :584.72UB 165
CAS :<p>Subtype-selective nicotinic agonist</p>Formule :C13H15ClN2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.72Holothurinogenin
CAS :<p>Holothurinogenin, as a lanosterol derivative, has toxic to nerve tissue.</p>Formule :C30H46O4Couleur et forme :SolidMasse moléculaire :470.68Antitubercular agent-23
<p>Antitubercular agent-23 combats Candida albicans (MIC: 1.1 μg/ml) and M. tuberculosis (MIC: 1 μg/ml).</p>Formule :C20H22FN5O8SCouleur et forme :SolidMasse moléculaire :511.48Cilobamine (free base)
CAS :<p>Cilobamine: a stimulant antidepressant, inhibits norepinephrine-dopamine reuptake, based on dichloroisoprenaline structure.</p>Formule :C17H23Cl2NOCouleur et forme :SolidMasse moléculaire :328.28GSK2945 hydrochloride
<p>GSK2945 HCl is a specific Rev-erbα antagonist, EC50: 21.5 μM (mouse), 20.8 μM (human), increases cholesterol 7α-hydroxylase.</p>Formule :C20H19Cl3N2O2SCouleur et forme :SolidMasse moléculaire :457.8SID 26681509 quarterhydrate
<p>SID 26681509 is a selective inhibitor of cathepsin L (IC50: 56 nM) and blocks Plasmodium falciparum (IC50: 15.4 μM) and Leishmania major (IC50: 12.5 μM).</p>Formule :C27H35N5O6SCouleur et forme :SolidMasse moléculaire :544.16Aurora inhibitor 1
CAS :<p>Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).</p>Formule :C23H25N9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.57Icariside F2
CAS :<p>Icariside F2 modestly inhibits α-glucosidase (4.6-12%) and has antioxidant properties, plus strong NF-κB inhibition (IC50: 16.25±2.19 μM).</p>Formule :C18H26O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.39M826
<p>M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity in</p>Formule :C28H45N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.7WM382
CAS :<p>WM382, a potent dual PMIX/X inhibitor, has IC50s of 1.4 nM/0.03 nM and effective against various malaria stages.</p>Formule :C29H36N4O4Couleur et forme :SolidMasse moléculaire :504.62Dehydelone
CAS :<p>Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer.</p>Formule :C27H39NO5SCouleur et forme :SolidMasse moléculaire :489.67E6201
CAS :<p>E6201, a dual kinase inhibitor, blocks MEK1/FLT3 and has anti-tumor/psoriasis effects with low IC50s: ERK2 (5.2 nM), JNK (91 nM), p38 MAPK (19 nM).</p>Formule :C21H27NO6Couleur et forme :SolidMasse moléculaire :389.44Antidepressant agent 2
<p>Antidepressant agent 2 showed significant antidepressant effects with a MED value of 0.1 mg/kg.</p>Formule :C21H22ClFN2O3SCouleur et forme :SolidMasse moléculaire :436.93Sargachromanol E
CAS :<p>Sargachromanol E is a compound isolated from the marine brown alga, Sargassum horneri. It has been studied for its inhibitory effect on skin ageing.</p>Formule :C27H40O4Couleur et forme :SolidMasse moléculaire :428.6TMC353121
CAS :<p>TMC353121 is an effective inhibitor of respiratory syncytial virus fusion (pEC50: 9.9).</p>Formule :C32H42N6O3Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :558.71RS 12254
CAS :<p>RS 12254 is a dopamine agonist and antihypertensive agent.</p>Formule :C28H40N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.63JAK2 JH2 binder-1
CAS :<p>JAK2 JH2 binder-1: potent, selective, Ki=37.1 nM, potential for studying myeloproliferative neoplasms.</p>Formule :C29H25N7O6SCouleur et forme :SolidMasse moléculaire :599.62ORP-101
CAS :<p>ORP-101: large, stable molecule with partial μ agonist, full κ antagonist properties.</p>Formule :C60H84N2O8Couleur et forme :SolidMasse moléculaire :961.3216(R)-Iloprost
CAS :<p>Iloprost, a potent prostacyclin analog, binds IP & EP1 receptors (Ki 11 nM), contains 16(S/R) isomers, and inhibits platelets (IC50 65 nM).</p>Formule :C22H32O4Couleur et forme :SolidMasse moléculaire :360.49Asimicin
CAS :<p>Asimicin is a effective complex I inhibitor.</p>Formule :C37H66O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :622.92LY 245769
CAS :<p>LY 245769 is an inhibitor of leukotriene E4 (LTE4).</p>Formule :C25H33F3N8OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.64Pparδ agonist 5
<p>Pparδ agonist 5 is a selective, orally active PPARδ agonist with an EC50 of 0.335 μM and better selectivity than GW0742.</p>Formule :C23H21F3N2O2SCouleur et forme :SolidMasse moléculaire :446.49Lentiginosine
CAS :<p>Lentiginosine is a selective amyloglucosidase inhibitor.</p>Formule :C8H15NO2Couleur et forme :SolidMasse moléculaire :157.21IDO2-IN-1
CAS :<p>IDO2-IN-1: potent oral IDO2 inhibitor, IC50 = 112 nM, for inflammatory autoimmunity research.</p>Formule :C21H21BrN10O3Couleur et forme :SolidMasse moléculaire :541.36Soyacerebroside II
CAS :<p>Soyacerebroside II is a Ca2+ ionophore; both I and II inhibit IL-18 in PBMCs and modulate immune responses.</p>Formule :C40H75NO9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :714.02BTK-IN-15
<p>BTK-IN-15: Oral BTK inhibitor, IC50 0.7 nM, induces cancer cell apoptosis, selective with anti-tumor effects.</p>Formule :C28H24FN5O2Couleur et forme :SolidMasse moléculaire :481.5216,16-Dimethyl prostaglandin E2
CAS :<p>16,16-Dimethyl prostaglandin E2 regulates hematopoietic stem cells via EP2/EP4 and Wnt, taken orally.</p>Formule :C22H36O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.52RWJ-56110
CAS :<p>protease-activated receptor-1 (PAR1) antagonist</p>Formule :C41H43Cl2F2N7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :790.73β-Glucuronidase/hCAII-IN-2
<p>β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.</p>Formule :C31H23NO8Couleur et forme :SolidMasse moléculaire :537.52α-Amylase-IN-1
CAS :<p>α-Amylase-IN-1 is an α-Amylase inhibitor (IC50: 0.5509 μM).</p>Formule :C18H18N2O3Degré de pureté :99.92%Couleur et forme :SoildMasse moléculaire :310.35HBV-IN-24
<p>HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.</p>Formule :C23H27NO6Couleur et forme :SolidMasse moléculaire :413.46HDAC10-IN-1
<p>HDAC10-IN-1 is a potent, selective HDAC10 inhibitor (IC50=58 nM) affecting autophagy in FLT3-ITD+ acute myeloid leukemia cells.</p>Formule :C18H23N3O2Couleur et forme :SolidMasse moléculaire :313.39VU6005806
CAS :<p>VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.</p>Formule :C17H16F3N7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.41MGAT2-IN-1
CAS :<p>MGAT2-IN-1 is an orally active monoacylglycerol acyltransferase (MGAT2)inhibitor (human and mouse MGAT2 with IC50 of 7.8 and 2.4 nM , respectively).</p>Formule :C27H21ClF5N7O3SCouleur et forme :SolidMasse moléculaire :654.01Anti-Influenza agent 3
<p>Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).</p>Formule :C16H22ClNOSCouleur et forme :SolidMasse moléculaire :311.87Protopine hydrochloride
CAS :<p>Protopine inhibits thromboxane, lowers intracellular calcium, and reduces cell adhesion by altering adhesive factors.</p>Formule :C20H20ClNO5Degré de pureté :98%Couleur et forme :Prisms From Alc SolidMasse moléculaire :389.83WW437
<p>WW437 is a histone deacetylase (HDAC) inhibitor that exhibits potent anti-breast cancer activity both in vitro and in vivo.</p>Formule :C23H27N5O4Couleur et forme :SolidMasse moléculaire :437.49TIY-7
<p>TIY-7 is a selective, orally active inhibitor of the promyosin receptor kinase (TRK) enzyme. TIY-7 exhibited anti-tumour effects in a mouse xenograft model.</p>Couleur et forme :SolidAntimalarial agent 3
<p>Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.</p>Formule :C15H16BrN3O2Couleur et forme :SolidMasse moléculaire :350.21Bleomycin Free Base
CAS :<p>Bleomycin Free Base, a glycopeptide antibiotic, halts DNA function and treats solid tumors.</p>Formule :C55H84N17O21S3Couleur et forme :SolidMasse moléculaire :1415.55Akt/NF-κB/JNK-IN-1
<p>Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signalling pathways.Akt/NF-κB/JNK-IN-1 exhibits an inhibitory effect on nitric oxide</p>Formule :C22H22N2O6Couleur et forme :SolidMasse moléculaire :410.42GSK-2878175
CAS :<p>GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formule :C27H23BClFN2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.81PIKfyve-IN-1
<p>PIKfyve-IN-1: potent, cell-active inhibitor for PIKfyve research, IC50=6.9 nM.</p>Formule :C20H21N5Couleur et forme :SolidMasse moléculaire :331.41KDOAM-25 trihydrochloride (2230731-99-2 free base)
<p>KDOAM-25 trihydrochloride, a selective KDM5 inhibitor (IC50: 19-71 nM), boosts H3K4 methylation and hinders MM1S cell growth.</p>Formule :C15H28Cl3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.77Elacestrant S enantiomer dihydrochloride
<p>Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.</p>Formule :C30H40Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.5615-keto-Prostaglandin E2
CAS :<p>15-keto-Prostaglandin E2, an endogenous metabolite, inhibits STAT3 activation through binding to Cys259 and regulates breast cancer cell growth and progression.</p>Formule :C20H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.45Tezampanel hydrate
CAS :<p>Tezampanel is used for the treatment of migraine, neuropathic pain.</p>Formule :C13H23N5O3Couleur et forme :SolidMasse moléculaire :297.35Dihydrophaseic acid
CAS :<p>Dihydrophaseic acid 3'-O-b-D-glucopyranoside (D3G) can increase the proliferation and differentiation of osteoblast cells and enhance bone formation, suggests</p>Formule :C15H22O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :282.33SHR902275
CAS :<p>SHR902275: potent RAF inhibitor, hits RAS mutations, oral use. cRAF IC50=1.6 nM, bRAFwt IC50=10 nM, bRAFV600E IC50=5.7 nM, hinders cell growth.</p>Formule :C26H23F3N4O4Couleur et forme :SolidMasse moléculaire :512.48SB 243213 dihydrochloride
CAS :<p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>Formule :C22H21Cl2F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.33Sekikaic Acid
CAS :<p>Sekikaic acid, a phenolic lichen metabolite in H. obscurata, has antioxidant and antiviral properties, inhibiting MLL1-CBP.</p>Formule :C22H26O8Couleur et forme :SolidMasse moléculaire :418.44ZK824859 hydrochloride
<p>ZK824859 hydrochloride: oral uPA inhibitor with IC50 of 79 nM (uPA), 1580 nM (tPA), 1330 nM (fibrin).</p>Formule :C23H23ClF2N2O4Couleur et forme :SolidMasse moléculaire :464.89MPro N3
CAS :<p>Mpro inhibitor blocks MHV-A29, HCoV-229E, FOPV (IC50: 2.7–8.8 μM), and SARS-CoV-2 (IC50: 16.8 μM) in plaque assays.</p>Formule :C35H48N6O8Couleur et forme :SolidMasse moléculaire :680.79RBM10-8
CAS :<p>RBM10-8 irreversibly inhibits human sphingosine-1- phosphate lyase (hS1PL) while behaving also as an enzyme substrate.</p>Formule :C17H36NO5PCouleur et forme :SolidMasse moléculaire :365.45Keap1-Nrf2-IN-5
CAS :<p>Keap1-Nrf2-IN-5 is a potent inhibitor of Keap1-Nrf2 PPI (Keap1-Nrf2 protein-protein interaction) (IC50: 4.1 μM, Kd: 3.7 μM).</p>Formule :C23H30N4O6SCouleur et forme :SolidMasse moléculaire :490.57SB-423557
CAS :<p>SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nM</p>Formule :C28H36N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.60ONO-9780307
CAS :<p>ONO-9780307 is a specific antagonist of LPA1 (lysophosphatidic acid receptor 1) (IC50: 2.7 nM).</p>Formule :C30H35NO7Couleur et forme :SolidMasse moléculaire :521.6HBV-IN-31
CAS :<p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>Formule :C23H18ClNO6Couleur et forme :SolidMasse moléculaire :439.85Fonadelpar
CAS :<p>Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.</p>Formule :C25H23F3N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.52AZD 4407
CAS :<p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>Formule :C19H21NO3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :375.5Laninamivir trifluoroacetate
CAS :<p>Laninamivir trifluoroacetate, a long-acting antiviral, treats and prevents Influenza A and B via nasal spray.</p>Formule :C15H23F3N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.363SLN124
<p>SLN124, a GalNAc-siRNA targeting TMPRSS6, may normalize iron balance by restoring ferroregulation.</p>Couleur et forme :SolidAFP-07
CAS :<p>AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor.</p>Formule :C22H29F2NaO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.45Musettamycin
CAS :<p>Musettamycin triggers erythroid differentiation in blood cells, acts like anthracycline antibiotics, but only inhibits gram-positive bacteria.</p>Formule :C36H45NO14Couleur et forme :SolidMasse moléculaire :715.74Seco-Duocarmycin SA
CAS :<p>Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.</p>Formule :C25H24ClN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.9322-HDHA
CAS :<p>22-HDHA is an oxidation product of docosahexaenoic acid .</p>Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.49GAT564
<p>GAT564, an allosteric CB1R modulator, shows EC50s of 87 nM (cAMP) & 320 nM (β-arrestin2) and lowers IOP effectively in glaucoma mice.</p>Formule :C20H16N2O2SCouleur et forme :SolidMasse moléculaire :348.42BMS-520
CAS :<p>BMS-520: potent oral S1P1 agonist, effective in rat arthritis and mouse multiple sclerosis model.</p>Formule :C23H17F3N4O4Couleur et forme :SolidMasse moléculaire :470.4PF-00489791
CAS :<p>PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.</p>Formule :C20H28N8O4SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :476.55NPEC-caged-(S)-3,4-DCPG
CAS :<p>mGlu8a agonist</p>Formule :C19H16N2O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.34Tetrahydrouridine dihydrate
<p>THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.</p>Formule :C9H20N2O8Couleur et forme :SolidMasse moléculaire :284.26(rel)-AR234960
CAS :<p>(rel)-AR234960 is an active relative configuration of AR234960. AR234960 is a non-peptide agonist of MAS.</p>Formule :C27H30FN5O5SCouleur et forme :SolidMasse moléculaire :555.63Complex III-IN-1
<p>Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.</p>Formule :C14H20ClNO2S2Couleur et forme :SolidMasse moléculaire :333.9CB1/2 agonist 1
<p>Potent CB1/2 agonist 1; crosses blood-brain barrier; anti-inflammatory, analgesic; for multiple sclerosis research.</p>Formule :C21H24BrFN2O2Couleur et forme :SolidMasse moléculaire :435.33L-365260 hemihydrate
<p>L-365260 hemihydrate: selective oral CCK-B/gastrin blocker, Ki=1.9/2.0 nM, competes with guinea pig receptors.</p>Formule :C24H24N4O3Couleur et forme :SolidMasse moléculaire :407.47H 218-54
CAS :<p>H 218-54 is a renin inhibitor.</p>Formule :C37H56N2O5SCouleur et forme :SolidMasse moléculaire :640.92Cap-dependent endonuclease-IN-2
<p>Cap-dependent endonuclease-IN-2 strongly blocks influenza A virus RNA polymerase; it's a CEN inhibitor.</p>Formule :C30H24FN3O7SCouleur et forme :SolidMasse moléculaire :589.59TH-6
<p>TH-6, a potent HDAC inhibitor (IC50: HDAC1-0.115, 2-0.135, 3-0.242, 6-0.138, 8-2.120 μM), blocks cell migration, invasion, and has anti-tumor properties.</p>Formule :C22H24FN3O5Couleur et forme :SolidMasse moléculaire :429.44BSc5367
CAS :<p>BSc5367 inhibits Nek1 kinase (IC50: 11.5 nM), key in cell cycle, DNA repair, impacting ALS, PKD, cancer.</p>Formule :C20H15N3O2Couleur et forme :SoildMasse moléculaire :329.35Amdinocillin methylacetate
CAS :<p>Amdinocillin methylacetate is a Synthetic penicillin.</p>Formule :C18H27N3O4SCouleur et forme :SolidMasse moléculaire :381.49Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Formule :C22H20Cl2N4SeCouleur et forme :SolidMasse moléculaire :490.29BTK-IN-6
<p>BTK-IN-6, a potent BTK inhibitor, may treat immune, cardiac, cancer, viral, inflammatory, metabolic, and neurological disorders.</p>Formule :C23H22FN5O3Couleur et forme :SolidMasse moléculaire :435.45AR antagonist 4
<p>AR antagonist 4 (Compound 67-b) is an orally active androgen receptor (AR) antagonist that acts on wild-type AR (IC50: 246.6 nM).</p>Formule :C29H36N4OCouleur et forme :SolidMasse moléculaire :456.62Mevidalen HBA
CAS :<p>Mevidalen (LY3154207), a potent D1 positive allosteric modulator, is in clinical trials for Lewy body dementia.</p>Formule :C31H35Cl2NO6Couleur et forme :SolidMasse moléculaire :588.52HPK1-IN-30
CAS :<p>HPK1-IN-30 is a potent inhibitor of HPK1. HPK1-IN-30 has potential for cancer disease research.</p>Formule :C25H23FN6Couleur et forme :SolidMasse moléculaire :426.49Chitin synthase inhibitor 12
<p>Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.</p>Formule :C23H21ClFN3O5Couleur et forme :SolidMasse moléculaire :473.88Lobaric acid
CAS :<p>Lobaric acid, from Stereocaulon lichen, has antioxidant and anticancer properties, inhibits PTP1B and 12(S)-LOX, and reduces TMV lesions in plants.</p>Formule :C25H28O8Couleur et forme :SolidMasse moléculaire :456.48Pefcalcitol
CAS :<p>Pefcalcitol is a novel antipsoriatic prodrug candidate containing a 16-en-22-oxa-vitamin D3 structure.</p>Formule :C26H34F5NO4Couleur et forme :SolidMasse moléculaire :519.54Amrubicin HCl
CAS :<p>Amrubicin (SM-5887), an anthracycline, treats lung cancer by inhibiting DNA replication and topoisomerase II, with less cardiac toxicity.</p>Formule :C25H25NO9Couleur et forme :SolidMasse moléculaire :483.471,9-Dideoxyforskolin
CAS :<p>The compound is an inactive analog of forskolin(an adenylyl cyclase activator).</p>Formule :C22H34O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.5EGFR/HER2-IN-7
<p>EGFR/HER2-IN-7: Potent, selective dual inhibitor for MCF-7 cancer; IC50: EGFR 0.18μM, HER2 0.146μM, DHFR 0.907μM.</p>Formule :C19H21N3O2SCouleur et forme :SolidMasse moléculaire :355.45L 668411
CAS :<p>L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.</p>Formule :C19H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.44MK-6913
CAS :<p>MK-6913 is a potent and selective agonist of estrogen receptor β.</p>Formule :C25H27N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.5MCTR1
CAS :<p>MCTR1, a pro-resolving mediator derived from DHA, promotes tissue repair and reduces inflammation by enhancing phagocytosis and decreasing eicosanoids.</p>Formule :C32H47N3O9SCouleur et forme :SolidMasse moléculaire :649.8EB-0156
<p>EB-0156: potent ER α-glucosidase inhibitor, IC50 of 0.0479/ <0.001 μM, N-substituted valerian, broad-spectrum antiviral potential.</p>Formule :C21H32N6O7Couleur et forme :SolidMasse moléculaire :480.51Antifungal agent 19
<p>Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).</p>Formule :C19H18F4O2Couleur et forme :SolidMasse moléculaire :354.34LasR-IN-2
<p>LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.</p>Formule :C21H16ClN3O2Couleur et forme :SolidMasse moléculaire :377.82Dihydrokainic acid
CAS :<p>EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake</p>Formule :C10H17NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :215.25TGR5 Receptor Agonist 3
CAS :<p>TGR5 Receptor Agonist 3 is a GPBAR1 agonist with EC50 of 16.4 nM (hTGR5) & 209 nM (mTGR5), ensures gallbladder safety and reduces filling.</p>Formule :C29H27N3O6Couleur et forme :SolidMasse moléculaire :513.54Sekdel sequence
CAS :<p>Sekdel sequence, as a signal, leads to retention of at least two proteins in the endoplasmic reticulum of animal cells.</p>Formule :C29H49N7O14Couleur et forme :SolidMasse moléculaire :719.74VEGFR-IN-3
CAS :<p>VEGFR-IN-3 inhibits cancer cell growth (OVCAR-4, MDA-MB-468) with IC50s: 0.29, 0.35μM. Used in cancer research.</p>Formule :C27H28N2O6Couleur et forme :SolidMasse moléculaire :476.52PD 134922
CAS :<p>PD 134922 is a HIV-1 protease inhibitors. Inactivation of the protease prevents infectious virion formation.</p>Formule :C37H61N5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :719.97Squalestatin 2
CAS :<p>Squalestatin 2 is an inhibitor of squalene synthase.</p>Formule :C33H44O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :648.6914α-Demethylase/DNA Gyrase-IN-1
<p>14α-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.</p>Formule :C26H22N4O4Couleur et forme :SolidMasse moléculaire :454.48LP-284
CAS :<p>LP-284 is a DNA alkylating agent effective against solid tumors and hematologic cancers like MCL.</p>Formule :C16H20N2O4Couleur et forme :SolidMasse moléculaire :304.34Tandutinib (MLN518) HCl
<p>Tandutinib antagonizes FLT3, PDGFR, and c-Kit with an IC50 of ~200 nM.</p>Formule :C31H43ClN6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :599.16BMS-066
CAS :<p>BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.</p>Formule :C19H21N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :379.42Ibafloxacine
CAS :<p>Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect against</p>Formule :C15H14FNO3Degré de pureté :97.67%Couleur et forme :SolidMasse moléculaire :275.27LSD1-IN-15
<p>LSD1-IN-15 inhibits LSD1, MAO-A/B with IC50s: 0.149, 0.028, 0.327 μM; arrests LNCaP cancer cell growth, IC50 9.9 μM.</p>Formule :C22H20N2OCouleur et forme :SolidMasse moléculaire :328.41PDE4-IN-12
<p>PDE4-IN-12 is a potent and safe PDE4 ubiquitous inhibitor that acts on PDE4 (IC50: 3.5 nM, SI: 2.71) and PDE7 (IC50: 15 nM, SI: 4.27).</p>Formule :C34H35NO6Couleur et forme :SolidMasse moléculaire :553.64Zurletrectinib
CAS :<p>Zurletrectinib is a tyrosine kinase inhibitor with potential as an antineoplastic agent.</p>Formule :C19H19F2N7O2Couleur et forme :SolidMasse moléculaire :415.4Mepixetil
<p>Mepixetil is a potent angiotensin II receptor antagonist[1].</p>Formule :C12H18N2O3Couleur et forme :SolidMasse moléculaire :238.28AChE-IN-10
<p>AChE-IN-10 (24r) inhibits AChE (IC50=2.4 nM), reducing amyloid buildup, tau phosphorylation, and promotes neuron health.</p>Formule :C23H27F2NO4SCouleur et forme :SolidMasse moléculaire :451.53Fosmanogepix
CAS :<p>Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.</p>Formule :C22H21N4O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.40S-HP210
<p>S-HP210: selective GR modulator, blocks NF-κB (IC50: 1.92 μM), non-toxic to mouse fibroblasts.</p>Formule :C22H19N3O2S2Couleur et forme :SolidMasse moléculaire :421.54MsbA-IN-2
<p>MsbA-IN-2 is a potent inhibitor of the lipopolysaccharide transporter MsbA and is able to act on E. coli MsbA (IC50: 2 nM).</p>Formule :C23H19Cl2NO3Couleur et forme :SolidMasse moléculaire :428.31Verrucarin A
CAS :<p>Verrucarin A, a mycotoxin from Myrothecium verrucaria, inhibits protein synthesis, leukemia growth, and triggers apoptosis.</p>Formule :C27H34O9Couleur et forme :SolidMasse moléculaire :502.55GSK789
CAS :<p>GSK789 is a selective inhibitor of the first bromodomains (BD1) of the bromo and extra terminal domain (BET) proteins.</p>Formule :C26H33N5O3Couleur et forme :SolidMasse moléculaire :463.57hAChE/Aβ1-42-IN-1
CAS :<p>Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and</p>Formule :C20H24N6OCouleur et forme :SolidMasse moléculaire :364.44KIRA9
<p>KIRA9 inhibits IRE1 with a 4.8 μM IC50, blocking ER-stress-induced mRNA decay and apoptosis by fully binding IRE1's ATP site.</p>Formule :C27H27F3N6O3SCouleur et forme :SolidMasse moléculaire :572.6Riminkefon
CAS :<p>Riminkefon is a kappa opioid receptor agonist .</p>Formule :C38H57N7O6Couleur et forme :SolidMasse moléculaire :707.9IRE1α kinase-IN-4
CAS :<p>IRE1α kinase-IN-4 (compound 6) is a potent inhibitor of IRE1α, exhibiting a Ki value of 140 nM. It acts as an ATP-competitive ligand for IRE1α [1].</p>Formule :C29H31N7O2Couleur et forme :SolidMasse moléculaire :509.6LasR-IN-3
<p>LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.</p>Formule :C22H19N3O2Couleur et forme :SolidMasse moléculaire :357.41RAD51-IN-5
CAS :<p>RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)</p>Formule :C26H38N4O5S2Couleur et forme :SolidMasse moléculaire :550.73Methyl 5-thia-6,8,11,14-eicosatetraenoate
CAS :<p>Methyl 5-thia-6,8,11,14-eicosatetraenoate is a bioactive chemical.</p>Formule :C20H32O2SCouleur et forme :SolidMasse moléculaire :336.53Mu opioid receptor antagonist 3
<p>Potent, selective MOR antagonist (compound 26); crosses blood-brain barrier. Ki: 0.24 nM, EC50: 0.54 nM; for studying OUD.</p>Formule :C25H28N2O4SCouleur et forme :SolidMasse moléculaire :452.57BChE-IN-2
<p>BChE-IN-2, a pyrimidine/pyridine derivative, potently inhibits BChE (Ki 0.099 μM) and shows promise in AD research.</p>Formule :C22H31N5Couleur et forme :SolidMasse moléculaire :365.52Geissoschizoline
CAS :<p>Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.</p>Formule :C19H26N2OCouleur et forme :SolidMasse moléculaire :298.42Alpibectir
CAS :<p>Alpibectir has antibacterial activity [1].</p>Formule :C12H14F6N2O2Couleur et forme :SolidMasse moléculaire :332.24HPK1-IN-3
<p>HPK1-IN-3: Selective HPK1 inhibitor, ATP-competitive, IC50=0.25nM; boosts IL-2 in PBMCs, EC50=108nM.</p>Formule :C23H22F4N6O2Couleur et forme :SolidMasse moléculaire :490.45Plasma kallikrein-IN-2
<p>Plasma kallikrein-IN-2: PKal inhibitor, IC50=0.1 nM. Used in angioedema, diabetic eye disease research.</p>Formule :C28H24ClF3N8O3Couleur et forme :SolidMasse moléculaire :612.99Cyclophilin inhibitor 1
CAS :<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formule :C31H39N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.67Antitubulin agent 1
<p>Antitubulin agents-1 disrupts microtubules, ups α-tubulin acetylation, and has anticancer properties.</p>Formule :C21H19N3O3Couleur et forme :SolidMasse moléculaire :361.39LSD1-IN-16
<p>LSD1-IN-16 (4b) inhibits LSD1, MAO-A/B; IC50: 0.015-0.366 μM. Halts prostate cancer cell growth; IC50: 15.2 μM.</p>Formule :C20H18N2OSCouleur et forme :SolidMasse moléculaire :334.43HPK1-IN-21
<p>HPK1-IN-21 is a potent, orally active HPK1 kinase inhibitor with a Ki value of 0.8 nM.</p>Formule :C22H25ClFN5O2Couleur et forme :SolidMasse moléculaire :445.925-HT7R antagonist 1
<p>5-HT7R antagonist 1 is a G protein-biased antagonist with Ki of 6.5 nM for 5-HT 7R.</p>Formule :C14H18Cl2N4Couleur et forme :SolidMasse moléculaire :313.23CD73-IN-7
CAS :<p>CD73-IN-7: potent inhibitor of CD73, blocks adenosine production to treat tumors.</p>Formule :C13H11ClN4O2Couleur et forme :SolidMasse moléculaire :290.7Ro 31-8472
CAS :<p>Ro 31-8472 is an angiotensin-converting enzyme (ACE) inhibitor and an analog of cilazaprilat.</p>Formule :C20H27N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.44MM-589
CAS :<p>MM-589 is a potent WD repeat domain 5 (WDR5) inhibitor and mixed lineage leukemia (MLL) protein-protein interaction.</p>Formule :C28H44N8O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.70LY 178210
CAS :<p>LY 178210 is a 5-hydroxytryptamine receptor agonist.</p>Formule :C18H25N3OCouleur et forme :SolidMasse moléculaire :299.41Anticancer agent 17
<p>Anticancer agent 17 was effective against HeLa cells (IC50: 0.19 μM) and A2780 cells (IC50: 0.09 μM).</p>Formule :C27H34BrN3OCouleur et forme :SolidMasse moléculaire :496.48Topo I/COX-2-IN-1
<p>Topo I/COX-2-IN-1: potent dual inhibitor; IC50 0.24μM (COX-2), 4.42μM (Topo I); anti-cancer; induces apoptosis, halts migration.</p>Formule :C21H18ClFN2O3Couleur et forme :SolidMasse moléculaire :400.83Lysyllysyllysine
CAS :<p>Lysyllysyllysine is a cationic moiety. It may be used in the construction of gene delivery vectors and DNA nanoparticles.</p>Formule :C18H38N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.53Tubulin polymerization-IN-33
<p>Tubulin-IN-33, an oxazoloisoindole, hinders microtubule assembly; effective against NCI cancer cells.</p>Formule :C27H28N2O6Couleur et forme :SolidMasse moléculaire :476.52GNE-616
CAS :<p>GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.</p>Formule :C24H23F4N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :537.53Tubulin inhibitor 22
<p>Compound 4c: Strong tubulin inhibitor with anti-cancer & anti-angiogenic effects; halts MGC-803 cells in G2/M, triggers Caspase-mediated apoptosis.</p>Formule :C20H17BrFNO4Couleur et forme :SolidMasse moléculaire :434.26JBJ-09-063
CAS :<p>JBJ-09-063: EGFR inhibitor, IC50s 0.147-0.396 nM for various mutants; hinders EGFR/Akt/ERK1/2 phosphorylation; targets TKI-sensitive/resistant lung cancer.</p>Formule :C31H29FN4O3SCouleur et forme :SolidMasse moléculaire :556.65SP4206
CAS :<p>SP4206 is an interaction inhibitor of IL-2/IL-2Rα (IL-2 and IL-2Rα with Kd of 70 nM and 10 nM,respectively)</p>Formule :C30H37Cl2N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :662.56BAY-850 HCl
<p>BAY-850 is a selective probe targeting Atad2A's bromine domain, displacing acetylated H4 peptides and detaching ATAD2 from chromatin at 1μm.</p>Formule :C38H48Cl5N5O3Couleur et forme :SolidMasse moléculaire :800.08Antimalarial agent 9
<p>Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.</p>Formule :C28H32BrN3O2Couleur et forme :SolidMasse moléculaire :522.48mTOR/HDAC6-IN-1
<p>mTOR/HDAC6-IN-1 inhibits HDAC6 (IC50: 56 nM) & mTOR (IC50: 133.7 nM), may treat TNBC by inducing autophagy and apoptosis.</p>Formule :C20H20ClN5O2Couleur et forme :SolidMasse moléculaire :397.86Esorubicin
CAS :<p>Esorubicin, a doxorubicin derivative, intercalates DNA, inhibits topoisomerase II, has less cardiotoxicity, but more myelosuppression.</p>Formule :C27H29NO10Couleur et forme :SolidMasse moléculaire :527.52DD04107
CAS :<p>DD04107 inhibits α-CGRP release, targets Synaptotagmin 1 in sensory neurons.</p>Formule :C48H88N14O12SCouleur et forme :SolidMasse moléculaire :1085.36NSC381467
CAS :<p>NSC381467: Potent, oral EGFR-TK inhibitor with strong antiproliferative effects, promising for cancer research.</p>Formule :C20H16O7Couleur et forme :SolidMasse moléculaire :368.34Fusarochromanone
CAS :<p>Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium oxysporum with potent antiangiogenic, anticancer and antimalarial activities.</p>Formule :C15H20N2O4Degré de pureté :95.31% - 96%Couleur et forme :SolidMasse moléculaire :292.33PDE4-IN-6
<p>PDE4-IN-6: Potent PDE4 inhibitor, IC50 - 0.125μM (B), 0.43μM (D), anti-inflammatory, for arthritis research.</p>Formule :C25H20FNO5SCouleur et forme :SolidMasse moléculaire :465.49CL656
CAS :<p>CL656 is a stimulator of interferon genes (STING) activator.</p>Formule :C20H21F2N9O9P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :695.51D4R antagonis-2
<p>Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.</p>Formule :C21H23ClF2N2O2Couleur et forme :SolidMasse moléculaire :408.87Epolactaene
CAS :<p>Epolactaene: neuritogenic, inhibits mammalian DNA polymerases & human DNA topoisomerase II.</p>Formule :C21H27NO6Couleur et forme :SolidMasse moléculaire :389.44L-I-OddU
CAS :<p>L-I-OddU: Selective anti-EBV, halts virus DNA/protein synthesis. EC50: 0.03 µM, low toxicity (CC50: 1000 nM).</p>Formule :C8H9IN2O5Couleur et forme :SolidMasse moléculaire :340.07Rostratin B
CAS :<p>Rostratin B, a cytotoxic disulfide, demonstrates in vitro cytotoxicity against human colon carcinoma (HCT-116), exhibiting an IC50 value of 1.9 μg/mL.</p>Formule :C18H20N2O6S2Couleur et forme :SolidMasse moléculaire :424.49EGFR-IN-45
<p>EGFR-IN-45: Strong EGFR/CDK2 inhibitor (IC50s: 0.4 & 1.6 μM), halts cancer cell cycle pre-G1, prompts apoptosis, also targets Topo I/II.</p>Formule :C28H23N7OCouleur et forme :SolidMasse moléculaire :473.53Diguanosine 5′-triphosphate lithium
<p>Diguanosine 5′-triphosphate (Gp3G) lithium is a dinucleoside triphosphate and a virus-specific oligonucleotide.Diguanosine 5′-triphosphate lithium is required</p>Formule :C20H27N10O18P3·xLiCouleur et forme :SolidIndoluidin E
<p>Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.</p>Formule :C28H30N4O2Couleur et forme :SolidMasse moléculaire :454.56ZBH-1205
CAS :<p>ZBH-1205, a camptothecin derivative, shows strong antitumor effects via apoptosis, outperforming cpt-11 and sn38 in topoisomerase-1 inhibition.</p>Formule :C29H31N3O8Couleur et forme :SolidMasse moléculaire :549.57DS69910557
<p>DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.</p>Formule :C32H33Cl2FN4O3Couleur et forme :SolidMasse moléculaire :611.53ONO-DI-004
CAS :<p>ONO-DI-004 is a selective EP1 Prostanoid receptor agonist.</p>Formule :C24H38O6Couleur et forme :SolidMasse moléculaire :422.55Aurora A inhibitor 1
CAS :<p>Aurora A inhibitor 1: potent, selective, targets cancer-linked Aurora A overexpression, potential for cancer research. (WO2021147974A1, 49)</p>Formule :C25H28ClF2N5O2Couleur et forme :SolidMasse moléculaire :503.97RSV-IN-5
CAS :<p>RSV-IN-5: Dual inhibitor for RSV fusion proteins, effective on wild-type A2 and D486N mutant with EC50s of 2.0 nM & 8.1 nM. Potent anti-RSV.</p>Formule :C28H37N7O2Couleur et forme :SolidMasse moléculaire :503.64HDAC6-IN-12
<p>HDAC6-IN-12 is a potent inhibitor of HDAC6 that binds in the DNA chain, causing DNA damage and exhibiting anticancer effects that can be used in cancer research</p>Formule :C24H39F2N3O5Couleur et forme :SolidMasse moléculaire :487.58KCa2 channel modulator 2
<p>Compound 2q is a potent, subtype-selective K/Ca 2 modulator, effective on human K Ca 2.3 and rat K Ca 2.2a with EC50s of 0.60 μM and 0.64 μM.</p>Formule :C16H15ClFN5Couleur et forme :SolidMasse moléculaire :331.78Carumonam Sodium
CAS :<p>Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials.</p>Formule :C12H12N6Na2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.37Pomaglumetad methionil
CAS :<p>Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.</p>Formule :C12H20N2O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.43JAK-IN-19
<p>JAK-IN-19 inhibits JAK (pIC50: 7.2, 7.7), less so for VEGFR2 (7.0) and Aurora B (5.8).</p>Formule :C26H36FN5O2Couleur et forme :SolidMasse moléculaire :469.59STAT3-IN-8
CAS :<p>"STAT3-IN-8 (compound H172) is a potent inhibitor of STAT3 with potential applications in cancer research [1]."</p>Formule :C19H7F7N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.26TGFβ1-IN-1
CAS :<p>TGFβ1-IN-1 is a TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in cancer research.</p>Formule :C22H24N2O3Degré de pureté :99.89% - 99.89%Couleur et forme :SolidMasse moléculaire :364.438LY 215890
CAS :<p>LY 215890 is a compound that exhibits potent Gram-negative and Gram-positive antibacterial activity.</p>Formule :C13H12ClN5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.78CXCR2 antagonist 6
<p>CXCR2 antagonist 6: strong CXCR2 affinity (IC50=0.044 μM), hinders calcium mobilization (IC50=0.66 μM).</p>Formule :C17H16F2N4OSCouleur et forme :SolidMasse moléculaire :362.4SB 258741 hydrochloride
<p>SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].</p>Formule :C19H31ClN2O2SCouleur et forme :SolidMasse moléculaire :386.98CK2-IN-3
<p>CK2-IN-3: potent, selective CK2 inhibitor; Kd=12 nM, IC50: 1.51 μM (CK2α), 7.64 μM (CK2α'). For cancer research.</p>Formule :C22H26N4O7Couleur et forme :SolidMasse moléculaire :458.46L 734217
CAS :<p>L 734217 is an antagonist of the fibrinogen receptor.</p>Formule :C18H31N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :353.46FPDT
<p>FPDT combats glioblastoma by inhibiting the AKT pathway; IC50: >100 μM (astrocytes), 45-68 μM (GBM cells).</p>Formule :C16H12FNO2SCouleur et forme :SolidMasse moléculaire :301.34PIM-1/HDAC-IN-1
<p>PIM-1/HDAC-IN-1 (4d): inhibits PIM-1 (IC50: 343.87nM), HDAC1 (63.65nM), HDAC6 (62.39nM); induces apoptosis in MCF-7 cells.</p>Formule :C22H19N3O3Couleur et forme :SolidMasse moléculaire :373.4AChE/GSK-3β-IN-1
CAS :<p>AChE/GSK-3β-IN-1 is a potent dual AChE/GSK-3β inhibitor that crosses the blood-brain barrier and acts on hAChE (IC50: 1.2 nM), hBChE (IC50: 149.8 nM) and hGSK-</p>Formule :C31H35N7O3SCouleur et forme :SolidMasse moléculaire :585.72Isobetanin
CAS :<p>Isobetanin is a betacyanin that has been shown to enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells.</p>Formule :C24H26N2O13Couleur et forme :SolidMasse moléculaire :550.47Symplostatin 1
CAS :<p>Symplostatin 1 is a dolastatin 10 analog from the marine cyanobacterium Symploca hydnoides.</p>Formule :C43H70N6O6SCouleur et forme :SolidMasse moléculaire :799.12DENV-IN-6
CAS :<p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>Formule :C23H26ClFN4OSCouleur et forme :SolidMasse moléculaire :461Ceclazepide
CAS :<p>Ceclazepide is an antagonist of cholecystokinin receptor.</p>Formule :C30H32N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.61KY-02327 acetate
<p>KY-02327 acetate inhibits Dvl-CXXC5, stabilizes Wnt/β-catenin signaling, and enhances osteoblast differentiation.</p>Formule :C22H31N3O6Couleur et forme :SolidMasse moléculaire :433.5
