Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.834 produits)
- Apoptose(6.315 produits)
- Cycle cellulaire/point de contrôle(4.878 produits)
- Chromatine/Épigénétique(2.613 produits)
- Signalisation du cytosquelette(1.568 produits)
- Altération de l'ADN/réparation de l'ADN(2.871 produits)
- Endocrinologie/Hormones(3.754 produits)
- Enzyme(3.672 produits)
- GPCR/G-Protéine(9.021 produits)
- Immunologie et Inflammation(3.904 produits)
- Virus de la grippe(300 produits)
- Signalisation JAK/STAT(415 produits)
- Signalisation MAPK(1.258 produits)
- Transporteur membranaire/Canal ionique(3.157 produits)
- Métabolisme(10.131 produits)
- Microbiologie/Virologie(7.620 produits)
- Neuroscience(10.484 produits)
- Autres inhibiteurs(35.844 produits)
- Oxydation-Réduction(40 produits)
- Signalisation PI3K/Akt/mTOR(1.429 produits)
- Protéases/Protéasome(1.689 produits)
- Cellules souche et Dérivés(731 produits)
- Tyrosine Kinase/Adaptateurs(1.982 produits)
- Ubiquitination(1.726 produits)
Affichez 16 plus de sous-catégories
66514 produits trouvés pour "Inhibiteurs"
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Chk1-IN-5
CAS :Chk1-IN-5 inhibits Chk1, blocking phosphorylation and suppressing colon cancer growth.Formule :C18H18FN7O2Couleur et forme :SolidMasse moléculaire :383.38CM-352
CAS :CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.Formule :C24H29N3O6SDegré de pureté :97.24%Couleur et forme :SolidMasse moléculaire :487.57DS17701585
DS17701585: Oral EP300/CBP inhibitor; potent on CBP, EP300, H3K27, & SOX2; useful for cancer research.Formule :C24H26N4O5SCouleur et forme :SolidMasse moléculaire :482.55RMI-18341
CAS :RMI-18341 is a Testosterone 5 alpha reductase inhibitor.Formule :C22H34N2O2Couleur et forme :SolidMasse moléculaire :358.52RET-IN-1
CAS :RET-IN-1 is a RET kinase inhibitor (IC50s: 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively).Formule :C29H31N9O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.61TAK-828F
CAS :TAK-828F: potent, selective RORγt inverse agonist. Oral. IC50=1.9 nM; reporter gene IC50=6.1 nM.Formule :C28H32FN3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :509.57Quinagolide hydrochloride
CAS :Quinagolide hydrochloride is a selective agonist of dopamine D2 receptor.Formule :C20H34ClN3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.02Antitumor agent-75
Antitumor agent-75 is a novel and potent antitumor agent.Formule :C26H23FN6Couleur et forme :SolidMasse moléculaire :438.5AM-3189
CAS :AM-3189: potent, selective GPR40 agonist with low CNS penetration, good pharmacokinetics, and efficacy mirroring AMG 837.Formule :C27H25ClN2O3Couleur et forme :SolidMasse moléculaire :460.95MDK6465
CAS :MDK6465 (PCSK9-IN-8b), CAS#1900686-46-5, is a liver-targeted PCSK9 synthesis inhibitor.Formule :C27H29ClFN9O4Couleur et forme :SolidMasse moléculaire :598.03Bizelesin
CAS :Bizelesin, a synthetic antineoplastic agent, binds DNA, disrupts replication, triggers cell-cycle arrest, and induces senescence.Formule :C43H36Cl2N8O5Couleur et forme :SolidMasse moléculaire :815.7Zorubicin
CAS :Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.Formule :C34H35N3O10Couleur et forme :SolidMasse moléculaire :645.66NSD2-IN-1
CAS :NSD2-IN-1: potent, selective NSD2-PWWP1 inhibitor, IC50 0.11 μM, induces gene expression changes, apoptosis, cell cycle arrest.Formule :C29H31N5Couleur et forme :SolidMasse moléculaire :449.59GSK2578999A
CAS :GSK2578999A is a betulin derivative with antitumor activity.Formule :C46H62ClNO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :776.44VEGFR-2-IN-5 hydrochloride
VEGFR-2-IN-5 hydrochloride is an effective VEGFR2 inhibitor.Formule :C19H25ClN8Couleur et forme :SolidMasse moléculaire :400.91Lp-PLA2-IN-6
CAS :Lp-PLA2-IN-6: Potent tetracyclic inhibitor of rhLp-PLA2, with pIC50 of 10.0, and potential in neurodegenerative research.Formule :C25H21F5N4O3Couleur et forme :SolidMasse moléculaire :520.45BAY-899
CAS :BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.Formule :C25H19F2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.45BM635 hydrochloride
BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.Formule :C25H30ClFN2OCouleur et forme :SolidMasse moléculaire :428.97Adafosbuvir
CAS :Adafosbuvir has antiviral activity.Formule :C22H29FN3O10PCouleur et forme :SolidMasse moléculaire :545.457SZ1676
CAS :SZ1676 is a derivative of SZ1677, which is an agent of neuromuscular blocking.Formule :C37H59BrN2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :707.78Scytonemin
CAS :Scytonemin, a cyanobacterial pigment, inhibits cancer cell growth by decreasing Plk1 activity, especially effective on U266 myeloma cells.Formule :C36H20N2O4Couleur et forme :SolidMasse moléculaire :544.55BU09059
CAS :BU09059 is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR).Formule :C28H37N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.61CHK1 inhibitor
CAS :CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.Formule :C17H21BrN4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.28(-)-Adenophorine
CAS :(-)-Adenophorine is a moderate alpha-l-fucosidase inhibitor.Formule :C8H17NO4Couleur et forme :SolidMasse moléculaire :191.22HIF-1α-IN-4
HIF-1α-IN-4 is an inhibitor of HIF-1α with IC50 of 24 nM in HEK293T cells which has potential antitumor effects.Formule :C16H12N2O3Couleur et forme :SolidMasse moléculaire :280.28MK-7128
CAS :MK-7128 is a CB1 receptor inverse agonist.Formule :C29H25ClF2N4O2Couleur et forme :SolidMasse moléculaire :534.98BET-IN-8
BET-IN-8 (Compound 27) is a potent inhibitor of BET (Ki: 0.83 μM, Kd: 0.571 μM), which ameliorates LPS-induced sepsis in vivo.BET-IN-8 has shown potential inFormule :C22H21N3O4SCouleur et forme :SolidMasse moléculaire :423.48(±)-ANAP hydrochloride
CAS :'(±)-ANAP hydrochloride, an unnatural amino acid analog of prodan, serves as a fluorescent probe with enhanced environmental sensitivity.'Formule :C15H17ClN2O3Couleur et forme :SolidMasse moléculaire :308.76Antibiotic MA 144M1
CAS :Antibiotic MA 144M1, an anthracycline, targets gram-positive bacteria and animal tumors; derived from Streptomyces fermentation or aclacinomycin A conversion.Formule :C42H55NO15Couleur et forme :SolidMasse moléculaire :813.88TTA-P1
CAS :TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.Formule :C19H27Cl2FN2OCouleur et forme :SolidMasse moléculaire :389.33Onfasprodil
CAS :Onfasprodil, NR2B inhibitor & GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)Formule :C20H23FN2O3Couleur et forme :SolidMasse moléculaire :358.41MI-1481
CAS :MI-1481: potent MML1 inhibitor, IC50 3.6 nM; disrupts menin-MLL1, active in MLL leukemia.Formule :C29H30F3N7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :597.65Lycopodine
CAS :Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of
Formule :C16H25NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :247.38GSD-11
GSD-11: Potent, selective anti-austerity agent; blocks Akt/mTOR pathway, hinders PANC-1 cell migration & colony growth. Promising for pancreatic cancer study.Formule :C20H28O2Couleur et forme :SolidMasse moléculaire :300.44GSK3368715
CAS :GSK3368715 is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50sFormule :C20H38N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.54GS-9822
CAS :GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.Formule :C36H39ClN4O4SCouleur et forme :SolidMasse moléculaire :659.24DHFR-IN-4
CAS :DHFR-IN-4 is a potent dihydrofolate reductase (DHFR) inhibitor with anti-tumour activity, inhibits EGFR and HER2 and can be used to study pancreatic cancer.Formule :C18H21N5O2SDegré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :371.46PROTAC CDK12/13 Degrader-1
PROTAC CDK12/13 Degrader-1 (7f) selectively degrades CDK12/13 at nanomolar potency, targeting breast cancer.Couleur et forme :Solidα-Glucosidase-IN-19
Alpha-Glucosidase-IN-19 (Compound 6B) is an orally active alpha-glucosidase inhibitor (IC50: 3.63 μM) with antidiabetic effects.Formule :C31H25NOSCouleur et forme :SolidMasse moléculaire :459.6Anticancer agent 14
Anticancer agent 14: a potent breast cancer inhibitor; induces cell death, disrupts mito. membrane potential (IC50: 0.20-0.65 μM).Formule :C29H34N2O3Couleur et forme :SolidMasse moléculaire :458.59Antileishmanial agent-4
Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].Formule :C17H18N4O4Couleur et forme :SolidMasse moléculaire :342.35NYX-2925
CAS :NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.Formule :C14H23N3O4Couleur et forme :SolidMasse moléculaire :297.35Glutaminyl cyclases-IN-1
Glutaminyl cyclase inhibitor IsoQC-IN-1: IC50=12 nM for QC, 73 nM for isoQC; blocks CD47/SIRPα; boosts THP-1, U937 macrophage phagocytosis.Formule :C25H30N6O2SCouleur et forme :SolidMasse moléculaire :478.61CDK9-IN-13
CDK9-IN-13 is a potent and selective CDK inhibitor (IC50<3 nM). CDK9-IN-13 has a very short half-life in rodents.Formule :C27H35N5O2Couleur et forme :SolidMasse moléculaire :461.6ERK2 IN-1
CAS :ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM.Formule :C36H34FN7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :647.76Terguride
CAS :Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.Formule :C20H28N4OCouleur et forme :SolidMasse moléculaire :340.46CPPG
CAS :CPPG: potent group II/III mGlu receptor antagonist, 20x more selective for group III (IC50: 2.2 nM) than II (46.2 nM) in rat cortex.Formule :C11H14NO5PCouleur et forme :SolidMasse moléculaire :271.21LTD4 antagonist 1
CAS :LTD4 antagonist 1 is a potent and orally active antagonist of leukotriene D4 (LTD4; Ki: 0.57 nM).Formule :C31H32F3N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :615.66Diacylglycerol acyltransferase inhibitor-1
CAS :Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.Formule :C21H23N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.44EGFR/HER2/DHFR-IN-1
Potent EGFR/HER2/DHFR inhibitor for MCF-7 breast cancer; IC50: 0.153/0.108/0.291 μM; arrests G1/S phase, triggers apoptosis.Formule :C14H11BrN4O2SCouleur et forme :SolidMasse moléculaire :379.23PRMT5-IN-3
CAS :PRMT5-IN-3 is a PRMT5 inhibitor.PRMT5-IN-3 is a combined DNA damaging agent that is synthetically lethal to tumor cells.Formule :C22H23F3N4O3Couleur et forme :SolidMasse moléculaire :448.44GNE-431
CAS :GNE-431: potent, selective noncovalent Btk inhibitor, IC50=3.2 nM; effective against C481R, T474I, T474M mutants, may counter ibrutinib resistance.Formule :C30H32N10O2Couleur et forme :SolidMasse moléculaire :564.64AFP-07
CAS :AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor.Formule :C22H29F2NaO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.45hCAIX/XII-IN-5
Coumarin 9a: Selective inhibitor of hCA IX/XII (Ki 93.3/85.7 nM), blocks cancer cell growth, and induces apoptosis.Formule :C18H13NO3Couleur et forme :SolidMasse moléculaire :291.3Aspochalasin M
CAS :Aspochalasin M shows moderate activity on HL-60 cells (IC50=20.0 μ M). Aspochalasin M has research potential in leukemia diseases.Formule :C24H35NO4Couleur et forme :SolidMasse moléculaire :401.54Tubulin inhibitor 22
Compound 4c: Strong tubulin inhibitor with anti-cancer & anti-angiogenic effects; halts MGC-803 cells in G2/M, triggers Caspase-mediated apoptosis.Formule :C20H17BrFNO4Couleur et forme :SolidMasse moléculaire :434.26Tubulin inhibitor 15
Tubulin inhibitor 15 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 15 exhibits cytotoxicity in HepG2 cells [1].Formule :C16H12FNO2Couleur et forme :SolidMasse moléculaire :269.27Ketomethylenebestatin
CAS :Ketomethylenebestatin, a weaker carba-analog of aminopeptidase inhibitor bestatin, is 10x less potent.Formule :C17H25NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :307.38hMAO-B/MB-COMT-IN-1
Dual hMAO-B/MB-COMT inhibitor, IC50: 2.5 μΜ (hMAO-B), 3.84 μΜ (MB-COMT); potential in Parkinson's research.Formule :C16H19NO3Couleur et forme :SolidMasse moléculaire :273.33AR-13324 M1 metabolite
CAS :AR-13324 M1 metabolite is a hydrolysis metabolite of AR-13324 mesylate.Formule :C19H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :321.37Calcipotriol Impurity C
CAS :Calcipotriol Impurity C is the impurity of Calcipotriol. Calcipotriol is a VDR-like receptors ligand.Formule :C27H40O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.614Resolvin D1 methyl ester
CAS :Resolvin D1, from docosahexaenoic acid via 15-/5-lipoxygenase, curbs acute inflammation; EC50 ~30 nM. Its methyl ester may enhance bioavailability.Formule :C23H34O5Couleur et forme :SolidMasse moléculaire :390.51H3R antagonist 2
Compound 23: H3R antagonist with 170 nM Ki; inhibits AChE, BChE, hMAO B; IC50s: 180, 880, 775 nM; anti-pain, memory boost; crosses BBB. [1]Formule :C24H29NO3Couleur et forme :SolidMasse moléculaire :379.49FAAH/MAGL-IN-2
CAS :FAAH/MAGL-IN-2: potent, reversible, oral FAAH & MAGL inhibitor, IC50: 11/36 nM, may research neuropathic pain, no locomotion issue.Formule :C15H13Cl2N3O3SCouleur et forme :SolidMasse moléculaire :386.25Nrf2/HO-1 activator 1
CAS :Compound 24: Potent Nrf2/HO-1 activator with neuroprotective, antioxidant properties; useful in PD research.Formule :C21H18O5Couleur et forme :SolidMasse moléculaire :350.36GSK3527497 HCl
CAS :GSK3527497: potent TRPV4 inhibitor, IC50=12 nM, targets heart/respiratory issues, for oral/IV use, low-dose effective.Formule :C17H17Cl2FN4O4SCouleur et forme :SolidMasse moléculaire :463.3054TIY-7
TIY-7 is a selective, orally active inhibitor of the promyosin receptor kinase (TRK) enzyme. TIY-7 exhibited anti-tumour effects in a mouse xenograft model.Couleur et forme :SolidCarbonic anhydrase inhibitor 4
CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.Formule :C21H18N2O4SCouleur et forme :SolidMasse moléculaire :394.44Befiradol hydrochloride
CAS :Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.Formule :C20H23Cl2F2N3ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :430.32GPX100 HCl
CAS :GPX-100, a non-cardiotoxic doxorubicin analog, intercalates DNA and inhibits replication, repair, and protein synthesis.Formule :C27H32ClNO10Couleur et forme :SolidMasse moléculaire :566LGB-321 HCl
CAS :LGB-321: potent, selective PIM kinase inhibitor, active against PIM2, halts diverse blood cancers' growth, orally effective in mice.Formule :C23H23ClF3N5O2Couleur et forme :SolidMasse moléculaire :493.91MDL-27788
CAS :MDL-27788 is a tricyclic inhibitor.Formule :C24H26N2O5SCouleur et forme :SolidMasse moléculaire :454.54Galectin-8-IN-1
Galectin-8-IN-1 selectively binds galectin-8N with 48 μM affinity, 15x more than galectin-3.Formule :C16H18N2O6Couleur et forme :SolidMasse moléculaire :334.32Antibacterial agent 99
CAS :Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.Formule :C27H27BrN2Couleur et forme :SolidMasse moléculaire :459.42MSA-2 dimer
CAS :MSA-2 dimer: selective oral non-nucleotide STING agonist, Kd=145 μM, long-term antitumor effect, non-covalent, higher permeability.Formule :C29H28O8S2Couleur et forme :SolidMasse moléculaire :568.66BMS-986339
CAS :BMS-986339: oral, potent FXR agonist; binds to His298/ASN287; for PBC, PSC, NASH, anti-fibrosis research.Formule :C35H41F4N3O4Couleur et forme :SolidMasse moléculaire :643.71CS-003 Free base
CAS :CS-003: Triple neurokinin receptor antagonist; Ki=2.3 nM (NK1), 0.54 nM (NK2), 0.74 nM (NK3); treats respiratory diseases.Formule :C34H38Cl2N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :673.65Eilatine
CAS :Eilatine is a novel marine alkaloid inhibits in vitro proliferation of progenitor cells in chronic myeloid leukemia patients.Formule :C24H12N4Couleur et forme :SolidMasse moléculaire :356.38ADU-S100 disodium salt
CAS :ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING).Formule :C20H22N10Na2O10P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :734.51Antibacterial agent 110
Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).Formule :C22H21N5O4SCouleur et forme :SolidMasse moléculaire :451.5Tabimorelin hemifumarate
CAS :orally active ghrelin receptor (GHS-R1a) agonistFormule :C32H40N403C4H404Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.72SB-423557
CAS :SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nMFormule :C28H36N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.60(-)-Mesembrine
CAS :Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4).Formule :C17H23NO3Couleur et forme :SolidMasse moléculaire :289.37NVP-CFC218
CAS :NVP-CFC218 is a novel potent and selective p53-HDM2 inhibitor.Formule :C37H45ClN4O4Couleur et forme :SolidMasse moléculaire :645.23GSK-2878175
CAS :GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.Formule :C27H23BClFN2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.81CXCR2 antagonist 4
CXCR2 antagonist 4 inhibits CXCR2 (IC50: 0.13 μM) and CXCL8-induced calcium rise (IC50: 27 μM), promising for cancer research.Formule :C15H14F2N4OS2Couleur et forme :SolidMasse moléculaire :368.42BAY 38-7271
CAS :BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) & 5.96 nM (CB2).Formule :C20H21F3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.44SC13
CAS :SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.Formule :C26H30N2O5Couleur et forme :SolidMasse moléculaire :450.53LLS30
CAS :LLS30 inhibits Gal-1, reduces its binding affinity, and may help treat advanced prostate cancer.Formule :C34H33Cl4N5O3Couleur et forme :SolidMasse moléculaire :701.47F 14679
CAS :F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.Formule :C21H25ClF2N4ODegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :422.9Imolamine hydrochloride
CAS :Imolamine hydrochloride is a blood platelet aggregation antagonist.Formule :C14H21ClN4OCouleur et forme :SolidMasse moléculaire :296.80MK-8318
CAS :MK-8318 is an effective and selective antagonist of the CRTh2 receptor (Ki: 5.0 nM).Formule :C27H26F4N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.5Macitentan (n-butyl analogue)
CAS :Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.Formule :C20H21Br2N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.2911-Oxahomoaminopterin
CAS :11-Oxahomoaminopterin exhibits antifolate activity against two folate-requiring microorganisms and inhibited Lactobacillus casei DHFR.Formule :C20H21N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.42FAK-IN-6
FAK-IN-6: Potent FAK inhibitor (IC50=1.415 nM), anti-cancer, for pancreatic studies.Formule :C25H31ClN5O6PSCouleur et forme :SolidMasse moléculaire :596.04DS-9300
CAS :DS-9300, an orally administered potent and selective inhibitor of EP300/CBP HAT, exhibits a significant inhibitory activity with an IC50 value of 28 nM.Formule :C25H26F3N5O3Couleur et forme :SolidMasse moléculaire :501.50Metoquizine
CAS :Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.Formule :C22H27N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48BMS-986120
CAS :BMS-986120: Oral, reversible PAR4 antagonist. IC50: 9.5 nM (human), 2.1 nM (monkey). Potent, selective antiplatelet.Formule :C23H23N5O5S2Couleur et forme :SolidMasse moléculaire :513.59Rostratin B
CAS :Rostratin B, a cytotoxic disulfide, demonstrates in vitro cytotoxicity against human colon carcinoma (HCT-116), exhibiting an IC50 value of 1.9 μg/mL.Formule :C18H20N2O6S2Couleur et forme :SolidMasse moléculaire :424.49L 734217
CAS :L 734217 is an antagonist of the fibrinogen receptor.Formule :C18H31N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :353.46XO/COX/LOX-IN-1
XO/COX/LOX-IN-1 targets XO/COX/LOX, used in research of inflammation, cancer, and metabolic disorders.Formule :C24H20N4O2SCouleur et forme :SolidMasse moléculaire :428.51Dopamine D3 receptor ligand-1
Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:Formule :C27H29N5OCouleur et forme :SolidMasse moléculaire :439.55Haspin-IN-2
CAS :Haspin-IN-2 is a potent haspin inhibitor (IC50: 50 nM) and also inhibits CLK1 (IC50: 445 nM) and DYRK1A (IC50: 917 nM).Formule :C12H8N4O3Couleur et forme :SolidMasse moléculaire :256.22Antitrypanosomal agent 5
Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).Formule :C30H30N6O4SCouleur et forme :SolidMasse moléculaire :570.66EB-0150
EB-0150 inhibits ER α-Glu I/II (IC50: 0.73/0.0337 μM), is an N-substituted valerian with antiviral effects, and has drug discovery potential.Formule :C19H30N6O7Couleur et forme :SolidMasse moléculaire :454.48Factor B-IN-3
CAS :Factor B-IN-3 is a potent inhibitor of complement factor B. Factor B-IN-3 can be used to study inflammatory and immune-related diseases.Formule :C24H29N3O4Couleur et forme :SolidMasse moléculaire :423.5Gepotidacin hydrochloride
CAS :Gepotidacin (GSK-2140944) is a potent DNA topoisomerase inhibitor, a novel antibacterial efficacious against various anaerobes.Formule :C24H29ClN6O3Couleur et forme :SolidMasse moléculaire :484.98Teslexivir
CAS :Teslexivir is a topical antiviral agent that is an effective and selective inhibitor of the interaction between two essential viral proteins, E1 and E2.Formule :C35H36BrN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :642.582,3-dinor-11β-Prostaglandin F2α
CAS :2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, whereFormule :C18H30O5Couleur et forme :SolidMasse moléculaire :326.43XY153
XY153 (8l) is a BD2 selective BET inhibitor targeting BRD4, 3 & 2 with IC50s: 0.79, 5.31 & 5.09 nM, useful in acute myeloid leukemia & cancer research.Formule :C33H34FN3O4Couleur et forme :SolidMasse moléculaire :555.64MK-7445
CAS :MK-7445 is a conformationally constrained inhibitor of non-nucleoside reverse transcriptase.Formule :C21H13Cl2N7OCouleur et forme :SolidMasse moléculaire :450.28CYP2C19-IN-1
CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.Formule :C26H26N2O6SCouleur et forme :SolidMasse moléculaire :494.56EGFR-IN-38
CAS :EGFR-IN-38: low-toxic acrylamide-derived EGFR inhibitor, targets NSCLC, patented for research on EGFR mutation-related diseases.Formule :C25H24ClN7O2Couleur et forme :SolidMasse moléculaire :489.96HP590
CAS :HP590: potent oral STAT3 inhibitor, IC50=27.8 nM, blocks ATP, IC50=24.7 nM, hinders gastric cancer growth, triggers cell death.Formule :C29H24F6N4O3Couleur et forme :SolidMasse moléculaire :590.52PRMT5-IN-18
CAS :PRMT5-IN-18 (Compound 002) is a potent inhibitor of PRMT5 and can be used in the study of PRMT5-mediated diseases, such as tumours.Formule :C32H42N4O4Couleur et forme :SolidMasse moléculaire :546.70Fusarochromanone
CAS :Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium oxysporum with potent antiangiogenic, anticancer and antimalarial activities.Formule :C15H20N2O4Degré de pureté :95.31% - 96%Couleur et forme :SolidMasse moléculaire :292.33SSR-241586
CAS :SSR-241586: Neurokinin antagonist, treats depression, schizophrenia, urinary issues, emesis, IBS.Formule :C32H42Cl2N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :601.61Hexedine
CAS :Hexedine is a biochemical.Formule :C22H45N3Couleur et forme :SolidMasse moléculaire :351.61CL656
CAS :CL656 is a stimulator of interferon genes (STING) activator.Formule :C20H21F2N9O9P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :695.51BDZ-h
CAS :BDZ-h inhibits both closed/open states of all 4 homomeric & 2 GluA2R-complex AMPA receptors.Formule :C21H21N5O3SCouleur et forme :SolidMasse moléculaire :423.49PDHK-IN-3
PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].Formule :C17H16N2O2Couleur et forme :SolidMasse moléculaire :280.32PPARγ agonist 1
PPARγ agonist 1 is a potent agonist of PPARγ that efficiently activates hPPARγ without causing full agonism, thereby avoiding adverse effects.Formule :C34H39NO3Couleur et forme :SolidMasse moléculaire :509.68Cav 3.2 inhibitor 1
Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.Formule :C32H39N3OCouleur et forme :SolidMasse moléculaire :481.67Ceclazepide
CAS :Ceclazepide is an antagonist of cholecystokinin receptor.Formule :C30H32N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.61DDCPPB-Glu
CAS :DDCPPB-Glu is a 6-5 fused ring heterocycle antifolate that shows antitumor activity.Formule :C22H27N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.48Mimocine
CAS :Mimosine, a plant amino acid, is known to act as a normoxic inducer of hypoxia-inducible factor (HIF).Formule :C15H14N2O5Couleur et forme :SolidMasse moléculaire :302.28CD73-IN-2
CD73-IN-2 is a potent inhibitor of CD73 (IC50: 0.09 nM).Formule :C17H25ClN5O7PCouleur et forme :SolidMasse moléculaire :477.84ZK-Thiazolidinone
CAS :ZK-Thiazolidinone (TAL), ATP-competitive PLK1 inhibitor, disrupts cell division processes in vitro and in vivo, targeting human/mouse tumors.Formule :C23H26F3N5O2SCouleur et forme :SolidMasse moléculaire :493.55Carmegliptin dihydrochloride
CAS :Carmegliptin dihydrochloride (RG-1579, RO4876904) is a salt of Camegliptin, a DPP-4 inhibitor for type 2 diabetes.Formule :C20H30Cl2FN3O3Couleur et forme :SolidMasse moléculaire :450.38GZN39838
CAS :GZN39838, a natural Kv1.2 blocker, induces C-type inactivation without blocking the outer pore.Formule :C22H30O6Couleur et forme :SolidMasse moléculaire :390.47DNA crosslinker 3 dihydrochloride
CAS :Compound 1: a DNA minor groove binder with 1.4°C ΔTm; useful in cancer research.Formule :C15H22Cl2N8OCouleur et forme :SolidMasse moléculaire :401.29FMK-MEA
CAS :FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.Formule :C21H26FN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.46Namitecan
CAS :Namitecan is an effective inhibitor of topoisomerase I. It has antitumor property.Formule :C23H22N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.44IL-17 modulator 1 disodium
CAS :Potent, orally active IL-17 Modulator 1 (disodium) from patent WO 2020127685, used in psoriasis and arthritis research.Formule :C28H37N6NaO6PCouleur et forme :SolidMasse moléculaire :607.604Luffariellolide
CAS :Luffariellolide is a terpene compound obtained from the marine sponge Hyrtios communis that is an HSF-PLA2 inhibitor and a RAR agonist.Formule :C25H38O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.57YKL-05-093
CAS :YKL-05-093 is a alt inducible kinase (SIK) inhibitor. YKL-05-093 increases bone formation and bone mass.Formule :C35H40N6O4Couleur et forme :SolidMasse moléculaire :608.73Glutaminyl Cyclase Inhibitor 3
CAS :Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.Formule :C24H32N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.61DNA-PK-IN-2
CAS :DNA-PK-IN-2 is an inhibitor of the DNA-PK enzyme complex, useful in cancer research.Formule :C20H23N5O3Couleur et forme :SolidMasse moléculaire :381.43GNTI dihydrochloride
CAS :κ opioid receptor antagonistFormule :C27H30ClN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.01S1PR1 agonist 1
CAS :S1PR1 agonist 1 is a potent agonist of S1PR1. S1PR1 agonist 1 has potential in autoimmune diseases.Formule :C29H30N4O4Couleur et forme :SolidMasse moléculaire :498.57I-BET282E
I-BET282E inhibits eight BET bromodomains (pIC50 6.4-7.7) with selectivity for other bromodomain proteins.Formule :C26H34N4O7SCouleur et forme :SolidMasse moléculaire :546.64Udifitimod
CAS :Udifitimod (BMS-986166) is a potent, selective, and orally active modulator of the S1P1R receptor, showing potential for research in autoimmune diseases.Formule :C25H33NO2Couleur et forme :SolidMasse moléculaire :379.54MY-875
MY-875 inhibits microtubule formation, binds like colchicine (IC50: 0.92 μM), activates Hippo pathway, and induces apoptosis with anticancer properties.Formule :C21H25NO6Couleur et forme :SolidMasse moléculaire :387.43CRV431
CAS :CRV431 is a novel Pan-Cyclophilin Inhibitor, potently inhibiting all cyclophilin isoforms tested - A, B, D, and G (IC50 values ranged from 1-7 nM).Formule :C67H122N12O13Couleur et forme :SolidMasse moléculaire :1303.76Gemilukast
CAS :Gemilukast (ONO-6950) is a cysteinyl leukotriene 1 and 2 receptor inhibitor that inhibits bronchoconstriction and is used in the treatment of asthma.Formule :C36H37F2NO5Degré de pureté :98.27% - 99.5%Couleur et forme :SolidMasse moléculaire :601.68Ref: TM-T11388
1mg109,00€5mg260,00€1mL*10mM (DMSO)344,00€10mg447,00€25mg865,00€50mg1.341,00€100mg2.385,00€TMC353121
CAS :TMC353121 is an effective inhibitor of respiratory syncytial virus fusion (pEC50: 9.9).Formule :C32H42N6O3Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :558.71Oberadilol
CAS :Oberadilol is a pyridazinone derivative with vasodilatory and beta-adrenergic blocking activities and type III phosphodiesterase inhibitory actionFormule :C25H30ClN5O3Couleur et forme :SolidMasse moléculaire :483.99CTX-712
CAS :CTX-712 is a potent inhibitor of cdc2-like kinase ( CLK ). CTX-712 inhibits inhibits cancer survival and cancer cell growth.Formule :C19H17FN8O2Couleur et forme :SolidMasse moléculaire :408.39Turoctocog alfa
CAS :Turoctocog alfa: recombinant FVIII from CHO cells for hemophilia A study.Couleur et forme :SolidFGFR-IN-6
CAS :FGFR-IN-6 (Compound 5) is an FGFR inhibitor.Formule :C23H22N6O3Couleur et forme :SolidMasse moléculaire :430.4616(S)-Iloprost
CAS :Iloprost, a potent prostacyclin analog, binds to human IP & EP1 receptors with high affinity; inhibits platelet aggregation effectively.Formule :C22H32O4Couleur et forme :SolidMasse moléculaire :360.49Pralatrexate, (R)-
CAS :Pralatrexate is a high-affinity DHFR inhibitor targeting RFC-1, used in cancer treatment and immunosuppression.Formule :C23H23N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.47Antibacterial agent 77
Antibacterial agent 77 (compound 12) is an antibacterial agent [1].Formule :C22H27N3OSCouleur et forme :SolidMasse moléculaire :381.53BM635 mesylate
BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.Formule :C26H33FN2O4SCouleur et forme :SolidMasse moléculaire :488.61COX-2-IN-9
COX-2-IN-9: potent oral COX-2 blocker, selective over Celecoxib, IC50 10.17 μM, less ulcers, strong anti-inflammatory.Formule :C25H23N5O4S2Couleur et forme :SolidMasse moléculaire :521.61Antibacterial agent 87
Antibacterial agent 87 is an effective antibacterial agent that acts on MRSA (MIC: 0.125 μg/ml), MRSE (MIC: 0.0625 μg/ml) and S. aureus (MIC: 0.0625 μg/ml).Formule :C31H46N2O6SCouleur et forme :SolidMasse moléculaire :574.77Acetomycin
CAS :Acetomycin, a γ-lactone from S. ramulosus, halts HCT-8 colon and L1210 leukemia cell growth.Formule :C10H14O5Couleur et forme :SolidMasse moléculaire :214.22Elacestrant S enantiomer dihydrochloride
Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.Formule :C30H40Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.56DIDS
CAS :DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.Formule :C16H10N2O6S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.52Merigolix
CAS :Merigolix is a potent gonadotrophin releasing hormone (GnRH) antagonist .Formule :C36H35F7N4O6Couleur et forme :SolidMasse moléculaire :752.68GSK1820795A
CAS :GSK1820795A: Telmisartan analog, selective hGPR132a antagonist, blocks yeast activation by N-acylamides, angiotensin II antagonist, partial PPARγ agonist.Formule :C35H34N8Couleur et forme :SolidMasse moléculaire :566.7Carbodine
CAS :Carbodine is an antiviral targeting CTP synthetase, effective against influenza A0/PR-8/34 and A2/Aichi/2/68.Formule :C10H15N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :241.24BI-44370
CAS :BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.Formule :C35H47N5O6Couleur et forme :SolidMasse moléculaire :633.78BRD4 D1-IN-1
BRD4 D1-IN-1 selectively inhibits BRD4 D1 (IC50 <0.092 μM, Kd 18 nM) with >500-fold specificity versus D2.Formule :C32H37F3N6OCouleur et forme :SolidMasse moléculaire :578.67Anticancer agent 45
Anticancer agent 46, potent and selective, induces apoptosis, is cytotoxic to cancer cells, with low toxicity to human lymphocytes.Formule :C22H14ClN3O6S2Couleur et forme :SolidMasse moléculaire :515.95K203
K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.Formule :C16H18Br2N4O2Couleur et forme :SolidMasse moléculaire :458.15Ascofuranone
CAS :Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODHFormule :C23H29ClO5Couleur et forme :SolidMasse moléculaire :420.93MRL-494
MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.Formule :C26H35FN16O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :622.66AM-9514
CAS :AM-9514: a potent Glucokinase activator with strong in vitro results, good pharmacokinetics, and efficacy in diabetes.Formule :C18H25N5O4Couleur et forme :SolidMasse moléculaire :375.42L-2'-Fd4C
CAS :L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].Formule :C9H10FN3O3Couleur et forme :SolidMasse moléculaire :227.19CXCR2 antagonist 5
CXCR2 antagonist 5 (compound 25) binds strongly (IC50=0.013μM) and mobilizes calcium (IC50=0.1μM).
Formule :C15H14F2N4O2SCouleur et forme :SolidMasse moléculaire :352.36SHR2415
SHR2415: Potent, selective ERK1/2 inhibitor, oral; ERK1 IC50: 2.8 nM, ERK2 IC50: 5.9 nM; effective in Colo205 (IC50: 44.6 nM), for cancer research.Formule :C23H22ClN7O2Couleur et forme :SolidMasse moléculaire :463.92Antitumor agent-58
Antitumor agent-58 suppresses tumor growth, colony formation, cell migration, and induces mitochondrial dysfunction in MGC-803 cells.Formule :C27H28F3N9SCouleur et forme :SolidMasse moléculaire :567.63Antibacterial agent 68
Antibacterial agent 68 targets drug-resistant E. coli at 0.007 mM with low cytotoxicity.Formule :C26H25BrN4O7Couleur et forme :SolidMasse moléculaire :585.4Seco-Duocarmycin SA
CAS :Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.Formule :C25H24ClN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.93Bcl-2-IN-7
Bcl-2-IN-7 inhibits Bcl-2, encourages apoptosis in cancer cells, and has anti-tumor activity with various IC50 values.Formule :C24H22N4O5S2Couleur et forme :SolidMasse moléculaire :510.59Cap-dependent endonuclease-IN-6
CAS :Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.Formule :C23H21N3O3SCouleur et forme :SolidMasse moléculaire :419.5Human carbonic anhydrase II-IN-2
Compound R-13, a potent inhibitor of hCA I/II/IV/IX with K i s of 60.7, 320.7, 2298, and 35.2 nM.Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5LPA5 antagonist 2
LPA5 antagonist 2, compound 65, water-soluble, reduces nociception, for inflammatory/neuropathic pain study.Formule :C26H25FN2O4SCouleur et forme :SolidMasse moléculaire :480.55SARS-CoV-2 nsp3-IN-1
Compound 15c selectively inhibits SARS-CoV-2 nsp3 Mac1 with IC50 of 6.1 μM.Formule :C17H15N5O2Couleur et forme :SolidMasse moléculaire :321.33Piceid 6″-O-azelaic acid ester
Piceid 6″-O-azelaic acid ester exhibited strong intracellular tyrosinase inhibition and decolorization activity.Formule :C24H36O10Couleur et forme :SolidMasse moléculaire :484.54GSK-1264
CAS :GSK-1264: allosteric HIV integrase inhibitor, halts viral replication & abnormal protein multimerization.Formule :C26H28FNO5Couleur et forme :SolidMasse moléculaire :453.5Calphostin B
CAS :Calphostins, PKC inhibitors from Cladosporium fungus, include A, B, C, D, I; C is most potent.Formule :C37H34O11Couleur et forme :SolidMasse moléculaire :654.66CD73-IN-12
CD73-IN-12, a compound from CN114437038A, shows strong anti-tumor activity by effectively inhibiting CD73 enzyme.Formule :C17H14F2N4O2Couleur et forme :SolidMasse moléculaire :344.32(RS)-AMPA
CAS :(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.Formule :C7H10N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :186.17(S)-JDQ-443
CAS :(S)-JDQ-443, an isomer of JDQ-443, is a selective, potent oral KRAS G12C inhibitor with antitumor properties.Formule :C29H28ClN7OCouleur et forme :SolidMasse moléculaire :526.03Dyrk1A/α-synuclein-IN-2
Dyrk1A/α-synuclein-IN-2 (Compound b20) is a dual inhibitor of Dyrk1A and α-synuclein aggregation that acts on α-synuclein (IC50: 7.8 μM).Formule :C21H16N4O4SCouleur et forme :SolidMasse moléculaire :420.44Npc 12626
CAS :Npc 12626 is a N-methyl-D-aspartate receptor antagonist; NPC 17742, the (2R,4R,5S)-isomer, is the most potent isomer in the mixture NPC 12626.Formule :C11H22NO5PCouleur et forme :SolidMasse moléculaire :279.27TRK-IN-12
CAS :TRK-IN-12 (9e), a macrocyclic TRK inhibitor (G595R IC50=13.1 nM), outperforms LOXO-101 in Ba/F3-NTRK1 cells.Formule :C18H19ClFN5O3SCouleur et forme :SolidMasse moléculaire :439.89PF-5177624
CAS :PF-5177624 is a selective and potent PDK1 inhibitor inducing anti-tumor activity in breast cancer cells.Formule :C25H25FN8O2Couleur et forme :SolidMasse moléculaire :488.52BET-IN-6
CAS :BET-IN-6: Potent BRD2/4 inhibitor and ligand for PROTAC BRD2/BRD4 degrader-1 synthesis.Formule :C22H20N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.47HDAC/Top-IN-1
CAS :HDAC/Top-IN-1, an oral HDAC/Top inhibitor, targets HDAC1-3,6,8 with low IC50s; blocks S-phase & induces apoptosis in HEL cells.Formule :C29H25FN4O4Couleur et forme :SolidMasse moléculaire :512.53D1R antagonist 1
CAS :Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].Formule :C22H26BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.35DSM705 hydrochloride
DSM705 hydrochloride: potent antimalarial, pyrrole-based DHODH inhibitor effective against Plasmodium, non-toxic to mammalian DHODH.Formule :C19H20ClF3N6OCouleur et forme :SolidMasse moléculaire :440.85HDAC-IN-35
HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.Formule :C17H13ClF3N3O3Couleur et forme :SolidMasse moléculaire :399.75Ambuic acid
CAS :Ambuic acid: cyclohexanone with antifungal, quorum-inhibiting, antibacterial properties, blocks cyclic peptides; reduces MRSA abscesses in mice.Formule :C19H26O6Couleur et forme :SolidMasse moléculaire :350.41Leukotriene B4 dimethyl amide
CAS :LTB4 dimethyl amide: inhibits human neutrophil degranulation and rat lysozyme release; antagonizes LTB4 receptor on guinea pig lung membranes (Ki = 130 nM).Formule :C22H37NO3Couleur et forme :SolidMasse moléculaire :363.53Nomelidine
CAS :Nomelidine, the active N-demethylated metabolite of zimelidine, has been used as an antidepressant and analgesic.Formule :C15H15BrN2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :303.20CD73-IN-13
CD73-IN-13, a potent CD73 inhibitor, may be developed for tumor-related disease treatment.Formule :C13H11F3N4O2Couleur et forme :SolidMasse moléculaire :312.25MALT1-IN-11
CAS :MALT1-IN-11: MALT1 inhibitor, IC50 <10-100 nM, reduces IL10, for cancer/autoimmune research.Formule :C20H16F4N8OCouleur et forme :SolidMasse moléculaire :460.39
