Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.834 produits)
- Apoptose(6.315 produits)
- Cycle cellulaire/point de contrôle(4.877 produits)
- Chromatine/Épigénétique(2.613 produits)
- Signalisation du cytosquelette(1.568 produits)
- Altération de l'ADN/réparation de l'ADN(2.871 produits)
- Endocrinologie/Hormones(3.754 produits)
- Enzyme(3.672 produits)
- GPCR/G-Protéine(9.020 produits)
- Immunologie et Inflammation(3.905 produits)
- Virus de la grippe(300 produits)
- Signalisation JAK/STAT(415 produits)
- Signalisation MAPK(1.257 produits)
- Transporteur membranaire/Canal ionique(3.155 produits)
- Métabolisme(10.133 produits)
- Microbiologie/Virologie(7.620 produits)
- Neuroscience(10.473 produits)
- Autres inhibiteurs(35.846 produits)
- Oxydation-Réduction(40 produits)
- Signalisation PI3K/Akt/mTOR(1.429 produits)
- Protéases/Protéasome(1.689 produits)
- Cellules souche et Dérivés(732 produits)
- Tyrosine Kinase/Adaptateurs(1.982 produits)
- Ubiquitination(1.726 produits)
Affichez 16 plus de sous-catégories
66515 produits trouvés pour "Inhibiteurs"
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D18
CAS :D18: Dual agonist for TLR7/8, boosts PD-L1, aids tumor sensitivity to PD-1/PD-L1 inhibitors, and is a cytotoxin for ADC HE-S2.Formule :C21H28N6Couleur et forme :SolidMasse moléculaire :364.49NusB-IN-1
NusB-IN-1 (22r) is an oral bacterial rRNA inhibitor, effective against MRSA and VRSA.Formule :C21H16N2O3Couleur et forme :SolidMasse moléculaire :344.36AKR1C3-IN-7
AKR1C3-IN-7 (Compound 13) is an effective and selective AKR1C3 inhibitor (IC50=0.19 μM). AKR1C3-IN-7 has antitumor activity.Formule :C24H20N2O4Couleur et forme :SolidMasse moléculaire :400.43TRK-IN-19
TRK-IN-19 (I-10) inhibits TRKA (1.1 nM IC50) & TRKAG595R (5.3 nM), promising for cancer research.Formule :C22H26FN5O2Couleur et forme :SolidMasse moléculaire :411.47ROPA
CAS :ROPA, a potent PKCalpha and PKCgamma activator, promotes tumor growth through PKC-activation.Formule :C28H32O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.55PDHK-IN-3
PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].Formule :C17H16N2O2Couleur et forme :SolidMasse moléculaire :280.32DNA crosslinker 4 dihydrochloride
CAS :DNA Crosslinker 4 binds DNA's minor groove, inhibits NCI-H460, A2780, MCF-7 cancer cells, and is used in cancer research.Formule :C16H24Cl2N8OCouleur et forme :SolidMasse moléculaire :415.32AChE-IN-22
AChE-IN-22 (10q) selectively inhibits AChE (IC50: 0.88 μM), less on BuChE (IC50: 10 μM), targets CAS and PAS, useful in Alzheimer's research.Formule :C21H20N4O5SCouleur et forme :SolidMasse moléculaire :440.47GG-43
GG-43 is a potent inhibitor of LIN28. The IC50 value of GG-43 against human LIN28A is 4 μM [1].Formule :C21H21NO3Couleur et forme :SolidMasse moléculaire :335.4MRTX-EX185
MRTX-EX185 inhibits GDP-KRAS/G12D; IC50=90 nM on G12D. It also binds GDP-HRAS.Formule :C33H33FN6O2Couleur et forme :SolidMasse moléculaire :564.65PF-06795071
CAS :PF-06795071 is an effective and selective covalent inhibitor of MAGL (IC50: 3 nM).Formule :C18H17F4N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.34Cap-dependent endonuclease-IN-5
CAS :Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.Formule :C27H21F2N3O4S2Couleur et forme :SolidMasse moléculaire :553.60PF-00446687
CAS :PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM).Formule :C28H36F2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.59Aβ-IN-2
Aβ-IN-2 is a peptide inhibitor of Aβ1-42.Formule :C37H51NOCouleur et forme :SolidMasse moléculaire :525.81Ten01
Ten01 exhibits a 5.0 nM inhibition of JAK1 kinase.Formule :C18H20F6N4OCouleur et forme :SolidMasse moléculaire :422.37LL-Z 1640-4
CAS :A signal-specific JNK/p38 pathway and TAK 1 inhibitorFormule :C19H24O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.39LY 215890
CAS :LY 215890 is a compound that exhibits potent Gram-negative and Gram-positive antibacterial activity.Formule :C13H12ClN5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.78Cemdomespib
CAS :Cemdomespib (KU-596) is a potent Hsp90 modulator with neuroprotective effects and can improve diabetic neuropathy.Formule :C24H30FNO6Couleur et forme :SolidMasse moléculaire :447.5Luffolide
CAS :Luffolide, a Luffariella sponge metabolite, shares manoalide's anti-inflammatory traits and fully inhibits PLA2's cleavage of phosphatidylcholine.Formule :C27H40O6Couleur et forme :SolidMasse moléculaire :460.60(+)-Sparteine sulfate pentahydrate
(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.Formule :C15H38N2O9SCouleur et forme :SolidMasse moléculaire :422.54DNA-PK-IN-8
CAS :DNA-PK-IN-8: Potent, selective oral DNA-PK inhibitor, IC50 = 0.8 nM, boosts anti-cancer effects with Doxorubicin.Formule :C19H22N8O2Couleur et forme :SolidMasse moléculaire :394.43P-gp/BCRP-IN-1
CAS :P-gp/BCRP-IN-1, safe and oral, inhibits P-gp/BCRP transporters, enhancing Paclitaxel bioavailability.Formule :C27H25ClN4O3Couleur et forme :SolidMasse moléculaire :488.97MK-8876
CAS :MK-8876 is an Inhibitor of HCV NS5B Site D.Formule :C32H24F2N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :614.624'-Ethynyl-2'-deoxyadenosine
CAS :4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).Formule :C12H13N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :275.26Sulprostone
CAS :EP3 and EP1 receptor agonistFormule :C23H31NO7SDegré de pureté :98%Couleur et forme :White To Off-White SolidMasse moléculaire :465.56Mimocine
CAS :Mimosine, a plant amino acid, is known to act as a normoxic inducer of hypoxia-inducible factor (HIF).Formule :C15H14N2O5Couleur et forme :SolidMasse moléculaire :302.283'-Hydroxy Repaglinide
CAS :'3'-Hydroxy Repaglinide, a CYP2C8 metabolite of Repaglinide, treats type II diabetes.Formule :C27H36N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.59264W94
CAS :264W94 robustly inhibits IBAT, induces CYP7A1, and significantly reduces cholesterol.Formule :C23H31NO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :417.56TLN-232
CAS :TLN-232, a synthetic heptapeptide, may inhibit cancer by targeting M2PK to disrupt tumor cell energy production.Formule :C36H49N9O7S2Couleur et forme :SolidMasse moléculaire :783.96TTA-P1
CAS :TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.Formule :C19H27Cl2FN2OCouleur et forme :SolidMasse moléculaire :389.33ACT-672125
CAS :ACT-672125: Potent CXCR3 blocker, may treat autoimmunity, safe with dose-dependent efficacy in lung inflammation.Formule :C25H25F3N10O2SCouleur et forme :SolidMasse moléculaire :586.59CTX-712
CAS :CTX-712 is a potent inhibitor of cdc2-like kinase ( CLK ). CTX-712 inhibits inhibits cancer survival and cancer cell growth.Formule :C19H17FN8O2Couleur et forme :SolidMasse moléculaire :408.39ZLMT-12
ZLMT-12: tacrine derivative, inhibits CDK2/CDK9, weak on AChE/BuChE, anti-proliferative, low toxicity, blocks S/G2/M phase, induces apoptosis.Formule :C26H31ClN6OCouleur et forme :SolidMasse moléculaire :479.02AA 497 (Free Base)
CAS :AA 497, a beta-2 agonist, causes relaxation and suppresses Ca spike frequency.Formule :C14H21NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :251.32GSK3368715 3HCl
CAS :GSK3368715, a potent inhibitor of type I protein arginine methyltransferases (PRMT), could inhibit PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81Formule :C20H41Cl3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :475.92JBJ-02-112-05
CAS :JBJ-02-112-05 is a potent, mutant-selective, allosteric and orally active inhibitor of EGFR with an IC 50 of 15 nM for EGFR L858R/T790M [1].Formule :C27H20N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.54Ro-24-4736
CAS :Ro 24-4736 is an effective and selective platelet-activating factor antagonist.Formule :C31H20ClN5OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :546.04GSK-3β inhibitor 6
GSK-3β inhibitor 6 is a highly potent inhibitor of GSK-3β, with an IC50 value of 24.4 μM.Formule :C20H17BrN4Couleur et forme :SolidMasse moléculaire :393.28MsbA-IN-3
MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).Formule :C24H22Cl2N2O4SCouleur et forme :SolidMasse moléculaire :505.41MraY-IN-3
MraY-IN-3 (12a) is a potent inhibitor of the bacterial translocase MraY (IC50: 140 μM). 46 μg/ml).Formule :C35H45N3O5Couleur et forme :SolidMasse moléculaire :587.75PD 140376
CAS :PD 140376: Selective CCK-B/gastrin receptor antagonist radioligand for guinea pig stomach & brain.Formule :C33H40N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.69Squalestatin 3
CAS :Squalestatin 3 is an inhibitor of squalene synthase.Formule :C25H30O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.5PAD-IN-2
CAS :PAD-IN-2, potent PAD4 inhibitor, IC50 <1 μM; targets autoimmune/cancer disorders.Formule :C27H28ClN5O2Couleur et forme :SolidMasse moléculaire :490KRAS G12C inhibitor 20
CAS :KRAS G12C inhibitor 20 is a KRAS G12C inhibitor.Formule :C33H37ClFN7O3Couleur et forme :SolidMasse moléculaire :634.14G092
G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter protein. G092 has potential for antibacterial drug research.Formule :C23H20Cl2N2O3Couleur et forme :SolidMasse moléculaire :443.32SHR902275
CAS :SHR902275: potent RAF inhibitor, hits RAS mutations, oral use. cRAF IC50=1.6 nM, bRAFwt IC50=10 nM, bRAFV600E IC50=5.7 nM, hinders cell growth.Formule :C26H23F3N4O4Couleur et forme :SolidMasse moléculaire :512.48Mal-PEG4-VA-PBD
CAS :Mal-PEG4-VA-PBD is a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), comprising the antitumor antibiotic Pyrrolobenzodiazepine (PBD), connectedFormule :C68H79N9O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1294.41ETX0282
CAS :ETX0282, oral class A/C β-lactamase inhibitor, developed by Entasis with cefpodoxime for bacterial infections.Formule :C13H18FN3O5Couleur et forme :SolidMasse moléculaire :315.30MRS2279
CAS :Selective, high affinity competitive antagonist of the P2Y1 receptorFormule :C13H18ClN5O8P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.71Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Formule :C16H11F2N3Couleur et forme :SolidMasse moléculaire :283.28Tribenuron
CAS :Tribenuron, a slow acting sulfonylurea herbicide, controls broadleaf weed.Formule :C14H15N5O6SCouleur et forme :SolidMasse moléculaire :381.36hDDAH-1-IN-2 sulfate
hDDAH-1-IN-2: selective oral hDDAH-1 inhibitor with low cell toxicity.Formule :C8H24N4O10S2Couleur et forme :SolidMasse moléculaire :400.43GC 14
CAS :GC 14 is a selective thyroid hormone receptor antagonist, with IC50 values of 200 nM and 35 nM for hTRα and hTRβ, respectively.Formule :C26H27NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :449.5FY-56
FY-56: potent, selective LSD1/KDM1A inhibitor (IC50=42nM); differentiates MOLM-13/MV4-11 cells; promising for AML research.Formule :C23H19FN2O3Couleur et forme :SolidMasse moléculaire :390.41hDHODH-IN-10
hDHODH-IN-10: selective oral inhibitor of hDHODH (IC50: 10.9 nM); blocks cancer cell growth, aids cancer research.Formule :C21H15ClF4N2O4Couleur et forme :SolidMasse moléculaire :470.8Antibacterial agent 62
Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.Formule :C24H33BrN2O2Couleur et forme :SolidMasse moléculaire :461.44Multi-kinase-IN-1
CAS :Multi-kinase-IN-1, a powerful kinase inhibitor, exhibits antitumor properties by inducing cell apoptosis.Formule :C35H36F2N6O6SCouleur et forme :SolidMasse moléculaire :706.76PD-1/PD-L1-IN-16
PD-1/PD-L1-IN-16 is a potent inhibitor of PD-1/PD-L1 (IC50: 53.2 nM) and has shown research potential for tumour immunotherapy.Formule :C34H30N4O4Couleur et forme :SolidMasse moléculaire :558.6311-trans Leukotriene E4
CAS :Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans LTE4 is equipotent to LTE4 in contracting guinea pig ileum.Formule :C23H37NO5SCouleur et forme :SolidMasse moléculaire :439.61KU 59403
CAS :KU 59403 is an effective ATM inhibitor (IC50: 3 nM, 9.1 μM, and 10 μM for ATM, DNA-PK, and PI3K, respectively).Formule :C29H32N4O4S2Degré de pureté :99.10%Couleur et forme :SolidMasse moléculaire :564.72Macitentan (n-butyl analogue)
CAS :Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.Formule :C20H21Br2N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.29Antitumor agent-43
Antitumor agent-43 (Compound 4B) is a potent antitumor agent that induces cell cycle arrest at G2/M phase.Formule :C16H8N2O3Couleur et forme :SolidMasse moléculaire :276.25Zanapezil fumarate
CAS :Zanapezil is an acetylcholinesterase (AChE) inhibitor. Zanapezil increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.Formule :C29H36N2O5Couleur et forme :SolidMasse moléculaire :492.619-cis-β-Carotene
CAS :9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal.Formule :C40H56Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :536.87Antibacterial agent 112
Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.Formule :C35H23N5O5Couleur et forme :SolidMasse moléculaire :593.59STING agonist-20
CAS :STING agonist-20: potent, aids in XMT-2056 synthesis, used as a cancer vaccine adjuvant.Formule :C36H39N11O8Couleur et forme :SolidMasse moléculaire :753.76BMS-986120
CAS :BMS-986120: Oral, reversible PAR4 antagonist. IC50: 9.5 nM (human), 2.1 nM (monkey). Potent, selective antiplatelet.Formule :C23H23N5O5S2Couleur et forme :SolidMasse moléculaire :513.59Bcl-2-IN-6
Bcl-2-IN-6 suppresses Bcl-2, upregulates p53/Bax/caspase-7, arrests cell cycle, and induces MCF-7 apoptosis; IC50s: MCF-7 20.91 μM, others <48 μM.Formule :C25H24N4O5S2Couleur et forme :SolidMasse moléculaire :524.61SARS-CoV-2-IN-8
SARS-CoV-2-IN-8 is a major protease inhibitor of SARS-CoV-2 (IC50: 0.75 μM).Formule :C35H38N6O3Couleur et forme :SolidMasse moléculaire :590.71D6808
D6808: selective c-Met inhibitor, IC50=2.9 nM, induces apoptosis and cell cycle arrest, for NSCLC/gastric cancer research.Formule :C30H25F3N6O2Couleur et forme :SolidMasse moléculaire :558.55Vimirogant hydrochloride
Vimirogant (VTP-43742) HCl: Oral, selective RORγt inhibitor (IC50: 17 nM, Ki: 3.5 nM), >1000x selectivity over RORα/β, targets Th17, not Th1/2/Treg.Formule :C27H36ClF3N4O3SCouleur et forme :SolidMasse moléculaire :588.21487BMS-751324
CAS :BMS-751324: p38α MAPK inhibitor with carbamyl-methyl, esters, phosphate from HPA. Reduces rat arthritis swelling and TNFα.Formule :C32H35N6O10PCouleur et forme :SolidMasse moléculaire :694.63Nnc 09-0026
CAS :Nnc 09-0026 is a neuronal calcium channel blockerFormule :C25H35Cl2F3N2OCouleur et forme :SolidMasse moléculaire :507.46YKL-1-116
CAS :YKL-1-116 is an effective, selective, and covalent CDK7 inhibitor.Formule :C34H38N8O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :606.72cis-4-Br-2,5-F2-PCPA
cis-4-Br-2,5-F2-PCPA (S1024) blocks LSD1/LSD2 (Ki: 94 nM/8.4 μM), hinders cancer stem cell growth, raises H3K4me2 in CCRF-CEM cells.Formule :C9H8BrF2NCouleur et forme :SolidMasse moléculaire :248.07CK156
CAS :CK156 inhibits DAPK with high selectivity; IC50: 182 nM (DRAK1), 34 μM (CK2a1), 39 μM (CK2a2); key in autoimmune/inflammation research.Formule :C21H25N5O3Couleur et forme :SolidMasse moléculaire :395.45CY208-243 Mandelate
CAS :CY208-243 is a D1 agonist boosting memory in T-maze, enhances adenylate cyclase (EC50=125nM), and alters monkey electroretinogram.Formule :C27H26N2O3Couleur et forme :SolidMasse moléculaire :426.52GRP78-IN-1
GRP78-IN-1 binds to GRP78 protein, inhibits cell growth, and triggers apoptosis in breast cancer; has -8.07 kcal/mol binding energy.Formule :C21H23FO3Couleur et forme :SolidMasse moléculaire :342.4L 156903
CAS :L 156903 is a bioactive chemical. It also inhibits the binding of neurotensin to brain tissue.Formule :C35H41N7O5SCouleur et forme :SolidMasse moléculaire :671.81AL-GDa62
AL-GDa62, a gastric cancer treatment lead, has EC50 of 3.2 μM (MCF10A-WT) and 2 μM (MCF10A-CDH1 -/-).Formule :C24H28FN3OCouleur et forme :SolidMasse moléculaire :393.5hCAII-IN-3
hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.Formule :C17H21N3O3SCouleur et forme :SolidMasse moléculaire :347.43C.I. Pigment Red 60
CAS :C.I. Pigment Red 60 is a bright, scarlet, semi-transparent red pigment.Formule :C17H9N2Na3O9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :518.35T-3764518
CAS :T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).Formule :C20H17F6N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.37EZH2-IN-12
EZH2-IN-12 (Compound 5) is a potent inhibitor of EZH2, which has potential for studies of CNS malignancies.Formule :C23H23Cl2N3O3Couleur et forme :SolidMasse moléculaire :460.35Antibacterial agent 69
Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 μM).Formule :C24H19N3O4SCouleur et forme :SolidMasse moléculaire :445.49Antifungal agent 43
Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.Formule :C24H26N4Se2Couleur et forme :SolidMasse moléculaire :528.412,3-dinor-11β-Prostaglandin F2α
CAS :2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, whereFormule :C18H30O5Couleur et forme :SolidMasse moléculaire :326.43AM-9514
CAS :AM-9514: a potent Glucokinase activator with strong in vitro results, good pharmacokinetics, and efficacy in diabetes.Formule :C18H25N5O4Couleur et forme :SolidMasse moléculaire :375.42Org-6906
CAS :DCB-3503, a tylophorine analog, may treat cancer and suppress immunity by blocking protein synthesis and modulating HSC70's ATPase activity.Formule :C13H16ClNDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :221.73AK-295
CAS :AK 295, also known as CX 295, is a dipeptide inhibitor of alpha-ketoamide calpain.Formule :C26H40N4O6Couleur et forme :SolidMasse moléculaire :504.62DAD
DAD is an ion channel blocker (blocks voltage-gated potassium channels) and is a third generation photoelectric switch that responds to visible light.Formule :C26H40N6OCouleur et forme :SolidMasse moléculaire :452.64KCa2 channel modulator 2
Compound 2q is a potent, subtype-selective K/Ca 2 modulator, effective on human K Ca 2.3 and rat K Ca 2.2a with EC50s of 0.60 μM and 0.64 μM.Formule :C16H15ClFN5Couleur et forme :SolidMasse moléculaire :331.78SB 258741 hydrochloride
SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].Formule :C19H31ClN2O2SCouleur et forme :SolidMasse moléculaire :386.98sEH inhibitor-4
Compound B15: potent sEH inhibitor (0.03 nm), reduces inflammation & pain.Formule :C27H28Cl2N4O3Couleur et forme :SolidMasse moléculaire :527.44Allosucrose
CAS :Allosucrose is a biochemical.Formule :C12H22O11Couleur et forme :SolidMasse moléculaire :342.30L 734217
CAS :L 734217 is an antagonist of the fibrinogen receptor.Formule :C18H31N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :353.46UCN-02
CAS :UCN-02 (7-epi-Hydroxystaurosporine) is a PKC inhibitor produced by Streptomyces N-126 strain, which inhibits PKA.Formule :C28H26N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :482.53Ro 0437626
CAS :P2X1 purinergic receptor antagonistFormule :C27H35N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :525.66Dihydrokainic acid
CAS :EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptakeFormule :C10H17NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :215.25Diospyrin
CAS :Diospyrin is a plant product that has significant inhibitory effect on the growth of Leishmania donovani promastigotes.Formule :C22H14O6Couleur et forme :SolidMasse moléculaire :374.34FTI-2628
CAS :FTI-2628 is a novel inhibitor of protein farnesyltransferase (FT), inhibiting the growth of P. falciparum in red blood cells and suppressing parasitemia.Formule :C31H34N4O3SCouleur et forme :SolidMasse moléculaire :542.69Antifungal agent 25
Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.Couleur et forme :SolidHS-731
CAS :HS-731 is a μ-Opioid Receptor Agonist.Formule :C20H26N2O5Couleur et forme :SolidMasse moléculaire :374.43(RS)-AMPA
CAS :(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.Formule :C7H10N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :186.17PTP1B-IN-3 diammonium
PTP1B-IN-3 diammonium, an oral enzyme inhibitor, has potent antidiabetic and anticancer effects, with a 120 nM IC50.Formule :C12H13BrF2N3O3PCouleur et forme :SolidMasse moléculaire :396.12FPDT
FPDT combats glioblastoma by inhibiting the AKT pathway; IC50: >100 μM (astrocytes), 45-68 μM (GBM cells).Formule :C16H12FNO2SCouleur et forme :SolidMasse moléculaire :301.34AFP464 free base
CAS :AFP464 (NSC710464) free base is an active HIF-1α inhibitor (IC50: 0.25 μM) and a potent aryl hydrocarbon receptor (AhR) activator.Formule :C22H23F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.44JAK3 covalent inhibitor-1
CAS :JAK3 Covalent Inhibitor-1 is a compound characterized by its potent and selective inhibition of Janus kinase 3 (JAK3), possessing an IC50 of 11 nM andFormule :C22H17FN6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.47MSK-195
CAS :MSK-195 is an effective TRPV1 agonist.Formule :C28H40N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.63SARS-CoV-2 nsp14-IN-1
SARS-CoV-2 nsp14-IN-1 inhibits Nsp14 Mtase with an IC50 of 0.061 μM, affecting multiple substrates.Formule :C20H20N6O5SCouleur et forme :SolidMasse moléculaire :456.48Henagliflozin
CAS :Henagliflozin (SHR3824): an oral, selective SGLT2 inhibitor, weak on SGLT1.Formule :C22H24ClFO7Couleur et forme :SolidMasse moléculaire :454.87SCP1-IN-1
CAS :SCP1-IN-1 (SH T-62) is a potent inhibitor of SCP1, promoting REST degradation and potentially aiding glioblastoma research.Formule :C20H19F3N2O7S2Degré de pureté :99.53%Couleur et forme :SoildMasse moléculaire :520.5Ref: TM-T60077
1mg49,00€5mg104,00€1mL*10mM (DMSO)119,00€10mg169,00€25mg311,00€50mg472,00€100mg707,00€Sinulatumolin E
CAS :Sinulatumolin E, a terpenoid, inhibits TNF-α (IC 50: 3.6 μM); has anti-inflammatory properties.Formule :C15H22O2Couleur et forme :SolidMasse moléculaire :234.33Hymenidin
CAS :Hymenidin, isolated from the Okinawan sponge Hymeniacidon sp., is a 5-hydroxytryptaminergic receptor antagonist and voltage-gated potassium channel inhibitor.Formule :C11H12BrN5ODegré de pureté :96.85% - 99.52%Couleur et forme :SolidMasse moléculaire :310.155-cis Carbaprostacyclin
CAS :5-cis Carbaprostacyclin: a PGI2 stable analog; poor human platelet aggregation inhibitor (IC50: 2.8 μM); weakens rabbit artery relaxation (EC50: 104 μM).Formule :C21H34O4Couleur et forme :SolidMasse moléculaire :350.49K027
K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer's disease.Formule :C15H18Br2N4O2Couleur et forme :SolidMasse moléculaire :446.14Antifungal agent 11
Antifungal agent 11 has a good antifungal effect.Formule :C21H19F2N7O3S2Couleur et forme :SolidMasse moléculaire :519.5512(S)-HETE
CAS :Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.
Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47(Rac)-OSMI-1
(Rac)-OSMI-1, a racemate, inhibits OGT (IC50: 2.7 μM) affecting O-GlcNAcylation without changing surface glycans.Formule :C28H25N3O6S2Couleur et forme :SolidMasse moléculaire :563.64PIM1-IN-3
PIM1-IN-3 (HL8) selectively blocks PIM1, induces Colo320 cell apoptosis, and may be researched for cancer.Formule :C27H25BrN6OCouleur et forme :SolidMasse moléculaire :529.43Trilobolide
CAS :Trilobolide is a natural counterpart of thapsigargin and an activator of cytokine secretion.Formule :C27H38O10Couleur et forme :SolidMasse moléculaire :522.58RWJ-445167
CAS :RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.Formule :C18H24N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.49PI3K-IN-23
PI3K-IN-23 is a (E)-9-oxooctadec-10-en-12-ynoic acid analogue that promotes glucose uptake (EC50: 7.00 μM).Formule :C24H33NO4SCouleur et forme :SolidMasse moléculaire :431.59rel-MDM2/4-p53-IN-3
rel-MDM2/4-p53-IN-3 inhibits MDM2/4-p53 PPI, IC50: MDM2 18.5nM, MDM4 14.8nM, targets cancer research.Formule :C25H24Cl2FN3O3Couleur et forme :SolidMasse moléculaire :504.38DSP-6952
CAS :DSP-6952 is a 5-HT4 receptor partial agonist, inhibiting visceral hypersensitivity and ameliorating gastrointestinal dysfunction.Formule :C21H32BrClN4O5Couleur et forme :SolidMasse moléculaire :535.86JAK-2/3-IN-3
JAK-2-/3-IN-3 (ST4j) is a potent JAK2/3 inhibitor for leukemia research, with IC50s: JAK2, 13 nM; JAK3, 14.86 nM; induces apoptosis.Formule :C13H10Cl2N4O2Couleur et forme :SolidMasse moléculaire :325.15MRS4738
MRS4738 is a potent antagonist with high affinity for the P2Y14R receptor. It demonstrates in vivo anti-hyperallodynic and antiasthmatic activity [1].Formule :C30H24F3NO2Couleur et forme :SolidMasse moléculaire :487.51FNDR-20123
FNDR-20123: First safe, effective anti-malarial HDAC inhibitor for Plasmodium (IC50: 31 nM) & human HDACs, with nanomolar potency across several subtypes.Formule :C21H24ClN5O2Couleur et forme :SolidMasse moléculaire :413.9Anti-TSWV agent 1
Anti-TSWV agent 1 is a highly effective inactivator (EC50:144 μg/mL) of tomato spotted wilt virus (TSWV).Formule :C22H27ClN4OS3Couleur et forme :SolidMasse moléculaire :495.12Antitubercular agent-16
Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.Formule :C21H27N3SCouleur et forme :SolidMasse moléculaire :353.52TMX-4113
TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1α(CK1α) degrader [1].Formule :C12H12N4O2S2Couleur et forme :SolidMasse moléculaire :308.38HDAC1-IN-5
HDAC1-IN-5 inhibits HDAC1 (IC50=15 nM) & HDAC6 (IC50=20 nM), promotes apoptosis, damages chromatin, and reduces tumor growth in mice.Formule :C20H21N3O2SCouleur et forme :SolidMasse moléculaire :367.46eeAChE-IN-1
eeAChE-IN-1 is a strong inhibitor of eeAChE (IC50: 23 nM).Formule :C27H30N6O5SCouleur et forme :SolidMasse moléculaire :550.63HER2-IN-7
CAS :HER2-IN-7 is a potent HER2 inhibitor with potential for researching ErbB-related diseases, especially cancer.Formule :C28H26F3N7O3Couleur et forme :SolidMasse moléculaire :565.55CDK9-IN-11
CAS :CDK9-IN-11 is a potent CDK9 inhibitor that is the ligand for the PROTAC CDK9 Degrader-1 [1].Formule :C20H25N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :371.43XN methyl pyrazole
XN methyl pyrazole exhibits beneficial effects on diet-induced obesity and enhances energy expenditure in mice fed with a high-fat diet [1].Formule :C22H24N2O4Couleur et forme :SolidMasse moléculaire :380.44Alpibectir
CAS :Alpibectir has antibacterial activity [1].Formule :C12H14F6N2O2Couleur et forme :SolidMasse moléculaire :332.24Deldeprevir Na
CAS :Deldeprevir Na is an Antiviral Polyprotein cleavage inhibitor. HCV NS3/4A inhibitor.Formule :C45H55F2N6NaO8S2Couleur et forme :SolidMasse moléculaire :933.08Tesirine
CAS :MP-PEG8-VA-PABC-PBD Dimer: ADC drug-linker for various cancers; DNA alkylating agent that blocks DNA replication.Formule :C75H101N9O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1496.65HOIPIN-8 sodium
CAS :HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.Formule :C23H15F2N4NaO3Degré de pureté :97.34%Couleur et forme :SolidMasse moléculaire :456.38Ref: TM-T62826
1mg66,00€5mg145,00€1mL*10mM (DMSO)146,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€200mg973,00€SDZ 220-040
CAS :SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂，可诱导根系生长的部分无重力模式 。Formule :C16H16Cl2NO6PDegré de pureté :98.13%Couleur et forme :SolidMasse moléculaire :420.18LLY-283
CAS :LLY-283, PRMT5 inhibitor, IC50 22 nM, Kd 6 nM, oral, selective, with antitumor effects.Formule :C17H18N4O4Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :342.35BE1218
CAS :BE1218 is a liver X receptor (LXR) inverse agonist active on LXRα and LXRβ with an IC50 of 9 nM and 7 nM, respectively.
Formule :C30H30FNO4S2Degré de pureté :99.7%Couleur et forme :SoildMasse moléculaire :551.69Darizmetinib
CAS :Darizmetinib (HRX215) is an MKK4 inhibitor.Formule :C21H17F2N5O3SDegré de pureté :98.03% - 99.57%Couleur et forme :SolidMasse moléculaire :457.45Ref: TM-T72956
1mg69,00€2mg89,00€5mg147,00€1mL*10mM (DMSO)148,00€10mg224,00€25mg324,00€50mg400,00€100mg587,00€Zelasudil
CAS :Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.Formule :C22H21F2N7ODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :437.445Ref: TM-T69665
1mg92,00€5mg168,00€1mL*10mM (DMSO)170,00€10mg248,00€25mg421,00€50mg587,00€100mg820,00€Dazostinag disodium
CAS :Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist.Cost-effective and quality-assured.Formule :C21H20F2N8Na2O10P2S2Degré de pureté :98.84% - 99.96%Couleur et forme :SolidMasse moléculaire :754.48Emprumapimod
CAS :Emprumapimod, an oral p38α MAPK inhibitor, targets RPMI-8226 cells, curbs LPS-induced IL-6; IC50: 100 pM; for cardiomyopathy, acute pain.Formule :C24H29F2N5O3Degré de pureté :99.21% - >99.99%Couleur et forme :SolidMasse moléculaire :473.52Umibecestat
CAS :Umibecestat inhibits human and mouse BACE-1 (IC50: 11 nM & 10 nM), potentially for Alzheimer's research.Formule :C19H15ClF7N5O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :513.8Ref: TM-T13253
1mg163,00€5mg334,00€1mL*10mM (DMSO)376,00€10mg485,00€25mg807,00€50mg1.099,00€100mg1.485,00€JNJ-6204
CAS :JNJ-6204 is a deuterated compound that efficiently inhibits CSNK1D and CSNK1E.Formule :C19H11D6FN6ODegré de pureté :97.42% - 99.87%Couleur et forme :SolidMasse moléculaire :370.41Moiramide B
CAS :Moiramide B is an acetyl coenzyme A carboxylase inhibitor with antimicrobial activity, strongly inhibiting Gram-positive bacteria.Formule :C25H31N3O5Degré de pureté :98.53% - 99.90%Couleur et forme :SolidMasse moléculaire :453.53DRB18
CAS :DRB18 inhibits GLUT proteins, altering glucose metabolism and inducing cancer cell death by G1/S arrest and oxidative stress.Formule :C22H23ClN2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :382.88Ref: TM-T22317
1mg89,00€5mg215,00€1mL*10mM (DMSO)236,00€10mg340,00€25mg687,00€50mg1.108,00€100mg1.485,00€500mg2.962,00€NRX-103095
CAS :NRX-103095 increases β-catenin binding to SCFβ-TrCP E3 ligase; EC50 is 163 nM for pSer33/Ser37 affinity boost.Formule :C22H16Cl2F3N3O3SDegré de pureté :99.85% - 99.95%Couleur et forme :SolidMasse moléculaire :530.35Ref: TM-T63730
1mg142,00€5mg344,00€1mL*10mM (DMSO)404,00€10mg557,00€25mg1.108,00€50mg1.783,00€100mg2.673,00€SJ6986
CAS :SJ6986 is a potent, selective and orally active GSPT1/2 degrader. SJ6986 degrades GSPT1 with a DC 50 of 2.1 nM (D max 99%) [1].Formule :C20H14F3N3O7SDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :497.4Ref: TM-T41257
5mg52,00€1mL*10mM (DMSO)59,00€10mg86,00€25mg140,00€50mg245,00€100mg378,00€500mg898,00€SY-5609
CAS :SY-5609 (CDK7-IN-3) is a selective non-covalent CDK7 inhibitor, with weak inhibitory activity against CDK2, CDK9 and CDK12.Cost-effective and quality-assured.Formule :C23H26F3N6OPDegré de pureté :99.34% - >99.99%Couleur et forme :SolidMasse moléculaire :490.46Ref: TM-T36038
25mgÀ demander50mgÀ demander1mg139,00€2mg200,00€5mg343,00€1mL*10mM (DMSO)373,00€10mg553,00€SB-423562
CAS :SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.Formule :C26H32N2O4Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :436.54Ref: TM-T12846
1mg37,00€5mg80,00€1mL*10mM (DMSO)89,00€10mg119,00€25mg210,00€50mg319,00€100mg442,00€200mg605,00€NRX-103094
CAS :NRX-103094 boosts β-catenin binding to SCFβ-TrCP ligase with EC50 62 nM and Kd 0.6 nM.Formule :C20H11Cl2F3N2O4SDegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :503.28Lometrexol
CAS :Lometrexol (LY 264618) is an antifolate that inhibits GARFT, blocks purine synthesis, induces apoptosis, and has anticancer properties.Formule :C21H25N5O6Degré de pureté :97.76% - 99.56%Couleur et forme :SolidMasse moléculaire :443.45Ref: TM-T15826
1mg84,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg505,00€50mg747,00€100mg1.035,00€200mg1.378,00€BODIPY FL prazosin
CAS :BODIPY FL prazosin is an α1-adrenergic antagonist that inhibits α1a-AR and α1b-AR.
Formule :C28H32BF2N7O3Degré de pureté :97.27%Couleur et forme :SolidMasse moléculaire :563.41AM103
CAS :AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).Formule :C36H38N3NaO4SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :631.76L-371,257
CAS :L-371,257 is a competitive antagonist of oxytocin receptor with pA2 of 8.4 and Ki of 19 nM. L-371,257 shows a Ki of 3.7 nM for vasopressin receptor 1a.Formule :C28H33N3O6Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :507.58Aleglitazar
CAS :Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.Formule :C24H23NO5SDegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :437.51Ref: TM-T14176
1mg233,00€5mg532,00€1mL*10mM (DMSO)538,00€10mg718,00€25mg1.099,00€50mg1.485,00€100mg1.998,00€INCB054329
CAS :INCB054329 is a BET inhibitor targeting BRD2/3/4 and BRDT with IC50s ranging from 1-119 nM.Formule :C19H16N4O3Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :348.36Vecabrutinib
CAS :Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.Formule :C22H24ClF4N7O2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :529.92Ref: TM-T17220
1mg82,00€5mg177,00€1mL*10mM (DMSO)207,00€10mg289,00€25mg470,00€50mg623,00€100mg874,00€MAO-B-IN-17
CAS :MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) for the study of central nervous system disorders like Parkinson's.Formule :C17H17F2NO2Degré de pureté :99.41%Couleur et forme :SoildMasse moléculaire :305.32NRX-252114
CAS :NRX-252114 promotes mutant β-catenin degradation, binding it to E3 ligase SCFβ-TrCP (EC50: 6.5 nM; Kd: 0.4 nM).Formule :C22H12Cl2F3N3O2SDegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :510.32STK-15
CAS :STK-15 is a candidate for use as a fatty acid binding protein 5 (FABP5) inhibitor.Formule :C34H29NO5Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :531.6BMS 299897
CAS :BMS 299897, a sulfonamide γ-secretase inhibitor, inhibits Aβ production with an IC50 of 7 nM in HEK293 cells overexpressing APP.Formule :C24H21ClF3NO4SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :511.94BAY-3827
CAS :BAY-3827 is an AMPK inhibitor with antiproliferative activity and antitumor activity. BAY-3827 inhibits the phosphorylation of acetyl CoA carboxylase 1.Formule :C27H25FN6ODegré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :468.53Ref: TM-T73350
1mg52,00€5mg113,00€1mL*10mM (DMSO)117,00€10mg177,00€25mg334,00€50mg560,00€100mg792,00€500mg1.575,00€AZD-5672
CAS :AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM.Formule :C32H38F2N2O5S2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :632.78Ref: TM-T30260
1mg192,00€5mg434,00€1mL*10mM (DMSO)530,00€10mg610,00€25mg888,00€50mg1.243,00€100mg1.693,00€Tuvusertib
CAS :Tuvusertib (M1774), an oral ATR inhibitor (Ki<1µM), selectively blocks CHK1 phosphorylation, disrupts DNA repair, and induces tumor cell apoptosis.Formule :C16H12F2N8ODegré de pureté :98.44% - 99.66%Couleur et forme :SolidMasse moléculaire :370.32Ref: TM-T10406
1mg58,00€5mg124,00€1mL*10mM (DMSO)142,00€10mg187,00€25mg363,00€50mg505,00€100mg717,00€(+)-Tetrabenazine
CAS :(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-foldFormule :C19H27NO3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :317.42Etamicastat hydrochloride
CAS :Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.Formule :C14H16ClF2N3OSDegré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :347.81Ref: TM-T11238L
1mg80,00€5mg173,00€1mL*10mM (DMSO)190,00€10mg259,00€25mg423,00€50mg577,00€100mg827,00€Vofopitant
CAS :Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).Formule :C21H23F3N6ODegré de pureté :97.86%Couleur et forme :SolidMasse moléculaire :432.44CCF0058981
CAS :CCF0058981: noncovalent inhibitor for SARS-CoV-2 & -1 proteases; IC50s: 68 nM (SC2) & 19 nM (SC1). Potential COVID-19 research use.
Formule :C24H19ClN6ODegré de pureté :98.94%Couleur et forme :SoildMasse moléculaire :442.9Ref: TM-T60095
500mgÀ demander1mg46,00€2mg60,00€5mg92,00€10mg160,00€25mg324,00€50mg449,00€100mg562,00€BMS-986141
CAS :BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614Formule :C27H23N5O5S2Degré de pureté :98.43% - 99.26%Couleur et forme :SolidMasse moléculaire :561.63Aldometanib
CAS :Aldometanib (LXY-05-029) is an oral aldolase inhibitor that maintains metabolic balance by blocking FBP and activating lysosomal AMPK.Formule :C27H43Cl2IN2Degré de pureté :99.32% - 99.55%Couleur et forme :SolidMasse moléculaire :593.46Tigemonam
CAS :Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.Formule :C12H15N5O9S2Degré de pureté :97.71% - >99.99%Couleur et forme :SolidMasse moléculaire :437.41NDI-034858
CAS :NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseasesFormule :C23H24N8O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :460.49PREP inhibitor-1
CAS :PREP inhibitor-1 is a prolyl oligopeptidase (PREP) inhibitor for the study of Alzheimer's disease.Formule :C22H28N4O2Degré de pureté :98.78%Couleur et forme :SoildMasse moléculaire :380.48BDZ-g
CAS :BDZ-g: potent, selective AMPA receptor antagonist; useful for researching neurological disorders.Formule :C21H21N5O2SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :407.49Eravacycline dihydrochloride
CAS :Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).Formule :C27H33Cl2FN4O8Degré de pureté :95% - 99.68%Couleur et forme :SolidMasse moléculaire :631.48AZ12601011
CAS :AZ12601011 is a TGFBR1 kinase inhibitor that inhibits the growth of breast tumors.Formule :C19H15N5Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :313.36Ref: TM-T10426
1mg99,00€5mg235,00€1mL*10mM (DMSO)259,00€10mg376,00€25mg728,00€50mg1.093,00€100mg1.510,00€ALOX15-IN-2
CAS :ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.Formule :C23H29N3O4SDegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :443.56Ref: TM-T62606
1mg46,00€5mg90,00€1mL*10mM (DMSO)100,00€10mg160,00€25mg313,00€50mg537,00€100mg767,00€500mg1.558,00€IDX184
CAS :IDX184 is a potent, orally active, targeted HCV polymerase inhibitor and nucleoside polymerase.IDX184 effectively inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3Formule :C25H35N6O9PSDegré de pureté :97.15%Couleur et forme :SolidMasse moléculaire :626.62Iclepertin
CAS :Iclepertin (BI-425809) is a GlyT1 inhibitor.Iclepertin is used for the treatment of Alzheimer;s disease and other CNS disorders.Formule :C20H18F6N2O5SDegré de pureté :98.89% - 98.93%Couleur et forme :SolidMasse moléculaire :512.42Ref: TM-T37089
1mg90,00€2mg114,00€5mg160,00€1mL*10mM (DMSO)173,00€10mg212,00€25mg349,00€50mg522,00€100mg783,00€200mg1.054,00€NB-360
CAS :NB-360: potent, brain-penetrant BACE1/2 inhibitor; IC50s: 5-6 nM; high selectivity vs pepsin, cathepsin E/D.Formule :C21H19F4N5O2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :449.4Ref: TM-T12188
1mg104,00€5mg215,00€1mL*10mM (DMSO)235,00€10mg318,00€25mg510,00€50mg692,00€100mg888,00€500mg1.783,00€FABPs ligand 6
CAS :FABPs ligand 6 (MF6) is an inhibitor of FABP5 and FABP7.Formule :C28H27FN2O3Degré de pureté :97.45%Couleur et forme :SolidMasse moléculaire :458.52Odevixibat
CAS :Odevixibat (A4250) is a selective oral inhibitor for ileal bile acid transport, potentially treating primary biliary cirrhosis.Formule :C37H48N4O8S2Degré de pureté :99.53% - 99.83%Couleur et forme :SolidMasse moléculaire :740.93Pocenbrodib
CAS :Pocenbrodib (FT-7051) is a potent inhibitor of the bromodomain of the CBP/p300 family with potential antitumour activity and is palatable for cancer research.Formule :C28H32FN3O6Degré de pureté :98.48% - 99.54%Couleur et forme :SolidMasse moléculaire :525.57USP5-IN-1
USP5-IN-1, a powerful USP5 deubiquitinase inhibitor, selectively binds with 2.8 μM affinity, blocking USP5's di-ubiquitin cleavage.
Formule :C19H20ClN3O5SDegré de pureté :99.76%Couleur et forme :SoildMasse moléculaire :437.9Dual FAAH/sEH-IN-1
CAS :Dual FAAH/sEH-IN-1 inhibits both sEH (IC50: 9.6 nM) and FAAH (IC50: 7 nM), offering potent anti-inflammatory effects.
Formule :C25H22ClN3O3S2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :512.04AZD 3147
CAS :AZD 3147 inhibits mTORC1 (40.7 nM), mTORC2 (5.75 nM), and PI3Kα/β/δ/γ (912/5495/9333/6310 nM IC50s).
Formule :C24H31N5O4S2Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :517.66HRO761
CAS :HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.Formule :C31H31ClF3N9O5Degré de pureté :98.74% - 99.62%Couleur et forme :SolidMasse moléculaire :702.08Ref: TM-T72107
1mg57,00€5mg118,00€10mg167,00€25mg280,00€50mg475,00€100mg708,00€1mL*10mM (DMSO)778,00€Gepotidacin mesylate dihydrate
CAS :Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an antibiotic and an inhibitor of bacterial type II topoisomerase.Formule :C25H36N6O8SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :580.65BQ-788
CAS :BQ-788 is an ETB receptor antagonist with potential hypertensive activity that inhibits exogenous ET-1-induced elevation of coronary perfusion pressure.Formule :C34H51N5O7Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :641.8Ref: TM-T10595
1mg130,00€2mg178,00€5mg313,00€1mL*10mM (DMSO)341,00€10mg447,00€25mg713,00€50mg964,00€100mg1.305,00€500mg2.592,00€Elacytarabine
CAS :Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.Formule :C27H45N3O6Degré de pureté :97.69%Couleur et forme :SolidMasse moléculaire :507.66LSN3318839
CAS :LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and canFormule :C26H23Cl2N3O2Degré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :480.39Treprostinil diethanolamine
CAS :Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1,Formule :C27H45NO7Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :495.65ELOVL1-IN-2
CAS :ELOVL1-IN-2 weakly inhibits ELOVL1 enzyme (IC50: 21 μM) and shows moderate potency in HEK293 cells (IC50: 6.7 μM).Formule :C18H15FN2ODegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :294.32KU-60019
CAS :KU-60019 is a specific inhibitor of ATM kinase (IC50: 6.3 nM).
Formule :C30H33N3O5SDegré de pureté :98.05% - 98.50%Couleur et forme :SolidMasse moléculaire :547.67
