Inhibiteurs
Les inhibiteurs sont des molécules qui se lient aux enzymes, récepteurs ou autres protéines pour réduire ou bloquer leur activité biologique. Ces composés sont largement utilisés en recherche pour étudier les voies biologiques, comprendre les mécanismes des maladies et développer des médicaments thérapeutiques. Les inhibiteurs jouent un rôle crucial dans le traitement de diverses maladies, y compris le cancer, les maladies cardiovasculaires et les infections. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité pour soutenir vos recherches en biochimie, biologie cellulaire et développement pharmaceutique.
Sous-catégories appartenant à la catégorie "Inhibiteurs"
- Angiogenèse(2.523 produits)
- Apoptose(5.792 produits)
- Cycle cellulaire/point de contrôle(4.449 produits)
- Chromatine/Épigénétique(2.238 produits)
- Signalisation du cytosquelette(1.383 produits)
- Altération de l'ADN/réparation de l'ADN(2.825 produits)
- Endocrinologie/Hormones(3.507 produits)
- Enzyme(3.640 produits)
- GPCR/G-Protéine(8.333 produits)
- Immunologie et Inflammation(3.526 produits)
- Virus de la grippe(296 produits)
- Signalisation JAK/STAT(404 produits)
- Signalisation MAPK(1.202 produits)
- Transporteur membranaire/Canal ionique(2.790 produits)
- Métabolisme(9.448 produits)
- Microbiologie/Virologie(6.981 produits)
- Neuroscience(9.926 produits)
- Autres inhibiteurs(37.926 produits)
- Oxydation-Réduction(41 produits)
- Signalisation PI3K/Akt/mTOR(1.400 produits)
- Protéases/Protéasome(1.597 produits)
- Cellules souche et Dérivés(831 produits)
- Tyrosine Kinase/Adaptateurs(2.016 produits)
- Ubiquitination(1.650 produits)
Affichez 16 plus de sous-catégories
66641 produits trouvés pour "Inhibiteurs"
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TAK-024
CAS :TAK-024 is an inhibitor of platelet(IC50s of 31, 79 and 51 nM in human, monkey and guinea pig, respectively).Formule :C27H34N10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.62HIF-1α-IN-4
<p>HIF-1α-IN-4 is an inhibitor of HIF-1α with IC50 of 24 nM in HEK293T cells which has potential antitumor effects.</p>Formule :C16H12N2O3Couleur et forme :SolidMasse moléculaire :280.28FLT3-IN-13
<p>FLT3-IN-13 inhibits topoisomerase II/FLT3 in leukemia with IC50 of 2.26 μM, causes G2/M arrest, and promotes apoptosis.</p>Formule :C20H14N4O2Couleur et forme :SolidMasse moléculaire :342.35PS-519
CAS :<p>PS-519 is a human tissue plasminogen activator and proteasome inhibitor.</p>Formule :C12H19NO4Couleur et forme :SolidMasse moléculaire :241.28Cemdomespib
CAS :<p>Cemdomespib (KU-596) is a potent Hsp90 modulator with neuroprotective effects and can improve diabetic neuropathy.</p>Formule :C24H30FNO6Couleur et forme :SolidMasse moléculaire :447.5Mevidalen HBA
CAS :<p>Mevidalen (LY3154207), a potent D1 positive allosteric modulator, is in clinical trials for Lewy body dementia.</p>Formule :C31H35Cl2NO6Couleur et forme :SolidMasse moléculaire :588.52KRAS G12D inhibitor 16
CAS :<p>KRAS G12D inhibitor 16 targets KRAS G12D with IC50 of 0.7 nM and mutant form at 0.35 μM, useful in various cancer studies.</p>Formule :C32H39IN6O3Couleur et forme :SolidMasse moléculaire :682.59SCH 563705
CAS :<p>SCH 563705 is a CXCR2 and CXCR1 antagonist used in the study of acute respiratory syndrome, chronic obstructive pulmonary disease, and inflammation.</p>Formule :C23H27N3O5Degré de pureté :98.03%Couleur et forme :SolidMasse moléculaire :425.48GDC-0339
CAS :<p>GDC-0339: oral Pim kinase inhibitor for multiple myeloma (Kis: Pim1 - 0.03 nM, Pim2 - 0.1 nM, Pim3 - 0.02 nM), well-tolerated.</p>Formule :C20H22F3N7OSCouleur et forme :SolidMasse moléculaire :465.5Valbenazine tosylate
CAS :<p>Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no</p>Formule :C38H54N2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :762.97HER2-IN-10
<p>HER2-IN-10 is a psoralen derivative that induces apoptosis. HER2-IN-10 shows anti-breast cancer activity and light-activated cytotoxicity [1].</p>Formule :C15H13NO5Couleur et forme :SolidMasse moléculaire :287.27AZ12971554
<p>AZ12971554: Human thrombin inhibitor, Ki=0.3nM; APTT IC50=0.68µM; ECT IC50=0.16µM.</p>Formule :C20H17ClFN7O3Couleur et forme :SolidMasse moléculaire :457.85AD5075
CAS :<p>AD5075 is a bioactive chemical.</p>Formule :C22H20N2O5SCouleur et forme :SolidMasse moléculaire :424.47GSK1820795A
CAS :<p>GSK1820795A: Telmisartan analog, selective hGPR132a antagonist, blocks yeast activation by N-acylamides, angiotensin II antagonist, partial PPARγ agonist.</p>Formule :C35H34N8Couleur et forme :SolidMasse moléculaire :566.7NS2B/NS3-IN-3
CAS :<p>NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .</p>Formule :C19H21N3O2Couleur et forme :SolidMasse moléculaire :323.39Lometrexol hydrate
CAS :<p>Lometrexol hydrate, an antipurine antifolate, inhibits GARFT and purine synthesis, leading to cancer cell apoptosis without causing DNA breaks.</p>Formule :C21H27N5O7Couleur et forme :SolidMasse moléculaire :461.475WS-898
<p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>Formule :C33H25N7OSCouleur et forme :SolidMasse moléculaire :567.66MK-3402
CAS :<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Formule :C15H19N9O5S2Couleur et forme :SolidMasse moléculaire :469.50SPR719
CAS :<p>SPR719 is an inhibitor of gyrase B, has bactericidal activity.</p>Formule :C21H25FN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.46SGLT inhibitor-1
CAS :<p>SGLT inhibitor-1 is a potentsodium glucose co-transporter proteins (SGLTs) dual inhibitor(hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively).</p>Formule :C24H27FO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.46JAK3-IN-7
CAS :<p>JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction after</p>Formule :C17H20N6ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :324.38NBD-10007
CAS :NBD-10007 is an inhibitor of HIV-1 entry.Formule :C20H25ClN4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.96Pibrozelesin
CAS :<p>Pibrozelesin, a water-soluble duocarmycin B2 derivative, binds AT-rich DNA, blocking replication and inducing cell death.</p>Formule :C32H36BrN5O8Couleur et forme :SolidMasse moléculaire :698.56c-Myc inhibitor 4
<p>Potent oral c-Myc inhibitor 4 reduces the proto-oncogene linked to tumor development.</p>Formule :C26H33FN6O3Couleur et forme :SolidMasse moléculaire :496.58TMX-4113
<p>TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1α(CK1α) degrader [1].</p>Formule :C12H12N4O2S2Couleur et forme :SolidMasse moléculaire :308.38eeAChE-IN-1
<p>eeAChE-IN-1 is a strong inhibitor of eeAChE (IC50: 23 nM).</p>Formule :C27H30N6O5SCouleur et forme :SolidMasse moléculaire :550.63MK-2748
CAS :<p>MK-2748 is an inhibitor of NS3 protease, hepatitis C virus.</p>Formule :C42H56N6O10SCouleur et forme :SolidMasse moléculaire :836.99TS010
<p>TS010 is a highly potent inhibitor of GLO-I, with an IC50 value of 0.57 μM. It holds significant promise for advancements in cancer research [1].</p>Formule :C16H12N4O4SCouleur et forme :SolidMasse moléculaire :356.36TRPV1 antagonist 3
<p>TRPV1 antagonist 3 (7q) strongly blocks TRPV1 at 2.66 nM IC50, is selective, 60% bioavailable, and crosses the blood-brain barrier.</p>Formule :C23H25N3OSCouleur et forme :SolidMasse moléculaire :391.53QPX7728 bis-acetoxy methyl ester
CAS :<p>QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.</p>Formule :C15H14BFO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.08BMS-986104 HCl
CAS :<p>BMS-986104 is a potent and selective S1P1 receptor modulator.</p>Formule :C22H36ClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.98Valopicitabine
CAS :<p>Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic</p>Formule :C15H24N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.37Thiolactomycin
CAS :<p>Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).</p>Formule :C11H14O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :210.29JAK3/BTK-IN-3
CAS :<p>JAK3/BTK-IN-3: strong dual JAK3/BTK suppressor, promising for autoimmune disease research.</p>Formule :C22H28N8OCouleur et forme :SolidMasse moléculaire :420.51MEIS-IN-3
<p>MEIS-IN-3 is a potent inhibitor of MEIS.</p>Formule :C25H26N2O4Couleur et forme :SolidMasse moléculaire :418.48DH376
CAS :<p>DH376 inhibits DAGLα in a time and dose dependent manner in mouse brain. DH376 shows picomolar activity.</p>Formule :C31H28F2N4O3Couleur et forme :SolidMasse moléculaire :542.58β-Glucuronidase/hCAII-IN-2
<p>β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.</p>Formule :C31H23NO8Couleur et forme :SolidMasse moléculaire :537.52CHK1-IN-4
CAS :<p>CHK1-IN-4 is a potent inhibitor of checkpoint kinase 1 (chk1) and potently inhibits chk1 phosphorylation in the tumor cells with anti-tumor activity.</p>Formule :C18H18BrN7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.29BTK-IN-6
<p>BTK-IN-6, a potent BTK inhibitor, may treat immune, cardiac, cancer, viral, inflammatory, metabolic, and neurological disorders.</p>Formule :C23H22FN5O3Couleur et forme :SolidMasse moléculaire :435.45Elacestrant S enantiomer
<p>Elacestrant S enantiomer is a selective and orally available estrogen receptor (ERR) degrader with IC50 values of 48 and 870 nM for ERα and ERβ, respectively.</p>Formule :C30H38N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.63ZIKV-IN-5
<p>ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.</p>Formule :C36H45NO4SiCouleur et forme :SolidMasse moléculaire :583.83DMP 728
CAS :<p>DMP 728 is an antagonist of Glycoprotein IIb-IIIa.</p>Formule :C26H40N8O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :656.71TP-030-2
CAS :<p>TP-030-2 is a RIPK1 inhibitor (human K i =0.43 nM ; mouse IC 50 =100 nM) .</p>Formule :C23H21BrN4O3Couleur et forme :SolidMasse moléculaire :481.34K203
<p>K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.</p>Formule :C16H18Br2N4O2Couleur et forme :SolidMasse moléculaire :458.15KRAS inhibitor-13
CAS :<p>KRAS inhibitor-13 blocks KRAS G12C (IC50: 0.883 μM) and p-ERK in some cancer cells; promising for pancreatic, colorectal, lung cancer research.</p>Formule :C25H19ClFN3O2SCouleur et forme :SolidMasse moléculaire :479.95TTA-P1
CAS :<p>TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.</p>Formule :C19H27Cl2FN2OCouleur et forme :SolidMasse moléculaire :389.33L 668411
CAS :<p>L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.</p>Formule :C19H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.44YKL-05-093
CAS :<p>YKL-05-093 is a alt inducible kinase (SIK) inhibitor. YKL-05-093 increases bone formation and bone mass.</p>Formule :C35H40N6O4Couleur et forme :SolidMasse moléculaire :608.73HG-12-6
CAS :<p>HG-12-6 is a type II IRAK4 inhibitor, targeting its inactive form with an IC50 of 165 nM, and is used in autoimmunity and inflammation.</p>Formule :C29H27F3N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :580.62PARP-1-IN-1
<p>PARP-1-IN-1: Selective, oral PARP-1 inhibitor with 0.96 nM IC50; well-tolerated and effective in single-dose MDA-MB-436 model.</p>Formule :C23H25FN4OCouleur et forme :SolidMasse moléculaire :392.47Rostratin B
CAS :<p>Rostratin B, a cytotoxic disulfide, demonstrates in vitro cytotoxicity against human colon carcinoma (HCT-116), exhibiting an IC50 value of 1.9 μg/mL.</p>Formule :C18H20N2O6S2Couleur et forme :SolidMasse moléculaire :424.49PTP1B-IN-19
<p>PTP1B-IN-19, a benzimidazole, selectively inhibits protein tyrosine phosphatase 1B with a Ki of 23.3 μM, potential for type 2 diabetes research.</p>Formule :C26H19N3O4SCouleur et forme :SolidMasse moléculaire :469.51HSP90-IN-10
<p>HSP90-IN-10 is a potent HSP90 inhibitor, targeting HCC1954 cells (IC50: 6 μM) and inducing apoptosis, sparing normal cells.</p>Formule :C30H26FN3O6Couleur et forme :SolidMasse moléculaire :543.541,9-Dideoxyforskolin
CAS :<p>The compound is an inactive analog of forskolin(an adenylyl cyclase activator).</p>Formule :C22H34O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.5GSK8814
CAS :<p>GSK8814 is a selective and ATAD2/2B bromodomain chemical probe and inhibitor (binding constant pKd=8.1 and a pKi=8.9 in BROMOscan).</p>Formule :C28H35F2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.61Sesamodil
CAS :<p>Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.</p>Formule :C29H32N2O6SDegré de pureté :98.58% - 99.01%Couleur et forme :SolidMasse moléculaire :536.64PPARγ agonist 2
<p>PPARγ agonist 2 is a highly effective compound that acts as a partial agonist for PPARγ.</p>Formule :C24H20O5Couleur et forme :SolidMasse moléculaire :388.41HBV-IN-19 TFA
CAS :<p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>Formule :C26H31F3N2O8Couleur et forme :SolidMasse moléculaire :556.53Cap-dependent endonuclease-IN-14
CAS :<p>Cap-dependent endonuclease-IN-14 hinders CEN and could treat influenza virus infections. (Patent CN113620948A, compound 1-c).</p>Formule :C30H23FN2O6SCouleur et forme :SolidMasse moléculaire :558.58ERα degrader 5
<p>ERα degrader 5 is an orally active, selective estrogen receptor (ER) reducer that acts on ERα (EC50: 1.1 nM). ERα degrader 5 shows anti-tumour effects in vivo.</p>Formule :C29H25F4N3O2SCouleur et forme :SolidMasse moléculaire :555.59ST362
CAS :<p>ST362, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.</p>Formule :C25H21NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :463.5Tuvatidine
CAS :<p>Tuvatidine is a histamine 2 receptor antagonist.</p>Formule :C10H17N9O2S3Couleur et forme :SolidMasse moléculaire :391.5KRAS G12D inhibitor 3
CAS :<p>KRAS G12D Inhibitor 3, a compound targeting the KRAS G12D mutation, demonstrates potent antitumor efficacy with an inhibitory concentration (IC50) of less than</p>Formule :C34H31ClF3N5O2Couleur et forme :SolidMasse moléculaire :634.09PI4KIIIbeta-IN-11
CAS :<p>PI4KIIIbeta-IN-11 is a PI4KIIIβ inhibitor (mean pIC50=9.1) that can be used to study diseases caused by RNA viruses and Plasmodium falciparum.</p>Formule :C33H39N7O3Couleur et forme :SolidMasse moléculaire :581.71Netupitant metabolite Monohydroxy Netupitant
CAS :<p>Monohydroxy Netupitant is a highly selective antagonist of NK1 receptor, and is Netupitant metabolite.</p>Formule :C30H32F6N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.59Carboxylesterase-IN-3
CAS :<p>Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.</p>Formule :C11H6Cl2N4OSDegré de pureté :97.49% - 98.47%Couleur et forme :SolidMasse moléculaire :313.16Trk-IN-8
<p>Trk-IN-8: TRK inhibitor with IC50 of 0.42 nM (TRKA), 0.89 nM (TRKA-G595R), 1.5 nM (TRKC-G623R).</p>Formule :C18H16F2N6O2Couleur et forme :SolidMasse moléculaire :386.36FPR2 agonist 2
<p>Potent FPR2 agonist, crosses blood-brain barrier, EC50: 0.13 nM; reduces inflammation and mitochondrial dysfunction, inhibits caspase-3.</p>Formule :C25H20F2N4O2Couleur et forme :SolidMasse moléculaire :446.45S1PR1 agonist 2
CAS :<p>S1PR1 agonist 2 is potent for autoimmune research (from WO2021175225A1).</p>Formule :C25H25N5O4Couleur et forme :SolidMasse moléculaire :459.50Naltrindole
CAS :<p>Naltrindole is a delta opioid receptor antagonist.</p>Formule :C26H26N2O3Couleur et forme :SolidMasse moléculaire :414.5Lysyllysyllysine
CAS :<p>Lysyllysyllysine is a cationic moiety. It may be used in the construction of gene delivery vectors and DNA nanoparticles.</p>Formule :C18H38N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.53GSK945237
CAS :<p>GSK945237 is a type IIA topoisomerase inhibitor, effective on Gram-positive and negative bacteria, with favorable pharmacokinetics and in vivo efficacy.</p>Formule :C24H26FN5O3Couleur et forme :SolidMasse moléculaire :451.49L 767679
CAS :<p>L 767679 is an antagonist of the fibrinogen receptors.</p>Formule :C20H24N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.43NR1H4 activator 1
CAS :<p>NR1H4 activator 1 is a potent and selective agonist of Famesoid X Receptor (FXR).</p>Formule :C34H53NO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :619.85BRD-9526
CAS :<p>BRD-9526 is a potent and selective inhibitor of Sonic Hedgehog (Shh).</p>Formule :C26H31Cl2N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :584.51OICR12694
CAS :<p>OICR12694 (JNJ-65234637) is an orally active inhibitor of B cell lymphoma 6 (BCL6) .</p>Formule :C29H28ClF3N8O4Couleur et forme :SolidMasse moléculaire :645.03Norbinaltorphimine dihydrochloride
CAS :<p>Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.</p>Formule :C40H45Cl2N3O6Degré de pureté :98.17% - 99.88%Couleur et forme :SolidMasse moléculaire :734.71ZM514
<p>ZM514 inhibits CD73 (hCD73 IC50: 1.39 μM, mCD73 IC50: 14.65 μM) with low cytotoxicity, suitable for cancer research.</p>Formule :C36H57NO4Couleur et forme :SolidMasse moléculaire :567.84AM-9514
CAS :<p>AM-9514: a potent Glucokinase activator with strong in vitro results, good pharmacokinetics, and efficacy in diabetes.</p>Formule :C18H25N5O4Couleur et forme :SolidMasse moléculaire :375.42SX 3202
CAS :<p>SX 3202 is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy.</p>Formule :C17H11BrFN3O4Couleur et forme :SolidMasse moléculaire :420.19BI-207524
CAS :<p>BI-207524 is a novel NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection.</p>Formule :C35H36ClN5O5Couleur et forme :SolidMasse moléculaire :642.14TAP311
<p>TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).</p>Formule :C34H40F6N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :710.71Dyrk1A-IN-1
<p>Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity, aggregation of tau and α-syn oligomers, with an IC50 value of 119 nM for Dyrk1A kinase.</p>Formule :C23H20N4O3SCouleur et forme :SolidMasse moléculaire :432.49Streptonigrin (racemate)
CAS :<p>Streptonigrin: aminoquinone antibiotic; antitumor, antibacterial; blocks β-Catenin/Tcf, cytotoxic; alters hamster chromosomes; (-)-isomer, CAS#3930-19-6.</p>Formule :C25H22N4O8Couleur et forme :SolidMasse moléculaire :506.462R,4R-Sacubitril
CAS :<p>2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.</p>Formule :C24H29NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.49Pexacerfont
CAS :<p>Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).</p>Formule :C18H24N6ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :340.42G-4120
CAS :<p>G-4120 is a biochemical that has been shown to have a dose-dependent complete inhibition of arterial and venous thrombosis.</p>Formule :C26H36N8O11SCouleur et forme :SolidMasse moléculaire :668.68Cyclophilin inhibitor 1
CAS :<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formule :C31H39N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.67Cathepsin C-IN-3
<p>Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).</p>Formule :C28H21F3N6OSCouleur et forme :SolidMasse moléculaire :546.57Cav 2.2/3.2 blocker 1
<p>Compound 9e is a Cav 2.2/3.2 blocker; IC50: 1.22 μM & 80 μM, respectively; penetrates CNS.</p>Formule :C28H30N2O3Couleur et forme :SolidMasse moléculaire :442.55MLKL-IN-1
<p>MLKL-IN-1 is a covalent inhibitor of MLKL with a Kd value of 50 μM.</p>Formule :C19H20N2O3Couleur et forme :SolidMasse moléculaire :324.37VRT-18858
CAS :<p>VRT-18858 is a metabolite of VX-740.</p>Formule :C24H25N5O7Couleur et forme :SolidMasse moléculaire :495.48RDN2150
CAS :<p>RDN2150 (Compound 25), a ZAP-70 inhibitor with an IC50 of 14.6 nM, covalently binds to the C346 residue of ZAP-70, suppressing the expression of CD25 and CD69</p>Formule :C28H29ClN8O4Couleur et forme :SolidMasse moléculaire :577.03GNE-886
CAS :<p>GNE-886 has a wide range of applications in life science related research.</p>Formule :C28H30N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.59Everafenib
<p>Everafenib: potent BRAF inhibitor, crosses blood-brain barrier, hinders MAPK, effective on V600EBRAF cells, outperforms other drugs in trials.</p>Formule :C20H23ClFN5O2S2Couleur et forme :SolidMasse moléculaire :484.01γ-Secretase modulator 11 hydrochloride
CAS :<p>γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM).</p>Formule :C28H23ClF2N4O2Couleur et forme :SolidMasse moléculaire :520.96α-Glucosidase-IN-18
<p>α-Glucosidase-IN-18 (7B) is an orally active inhibitor of α-glucosidase, displaying an IC 50 value of 3.96 μM.</p>Formule :C23H19NO2SCouleur et forme :SolidMasse moléculaire :373.47OncoFAP
CAS :<p>OncoFAP is an ultra-high affinity fibroblast activating protein (FAP) ligand with potential tumour targeting.</p>Formule :C21H19F2N5O5Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :459.40SARS-CoV-2-IN-24
<p>SARS-CoV-2-IN-24 blocks PLpro, altering its shape and stopping virus replication—useful for SARS-CoV-2 research.</p>Formule :C27H30N4O5Couleur et forme :SolidMasse moléculaire :490.55BMT-052
CAS :<p>BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).</p>Formule :C30H17D9F4N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :635.61AP5
CAS :<p>AP5: GPR40 agonist, positive allosteric modulator; rat hIP1 EC50: 0.49 nM.</p>Formule :C28H28FNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.52VGD071
CAS :<p>VGD071, a compound that targets sortilin, presents a promising avenue for forthcoming research utilizing mouse models of breast cancer.</p>Formule :C32H41N3O4S2Couleur et forme :SolidMasse moléculaire :595.82Kaitocephalin
CAS :<p>Kaitocephalin: naturally occurring, non-selective antagonist blocking glutamate receptors, made by Eupenicillium shearii fungus.</p>Formule :C18H21Cl2N3O9Couleur et forme :SolidMasse moléculaire :494.28PD-1/PD-L1-IN-23
CAS :<p>PD-1/PD-L1-IN-23: potent, oral PD-1/PD-L1 inhibitor; L7's ester prodrug; exhibits strong antitumor effects.</p>Formule :C32H30BrCl2N3O6Couleur et forme :SolidMasse moléculaire :703.41RMS-07
CAS :<p>RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.</p>Formule :C35H40N8O2Couleur et forme :SolidMasse moléculaire :604.74A25822B
CAS :<p>A25822B is an antifungal agent.</p>Formule :C28H45NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.66Pralatrexate, (R)-
CAS :<p>Pralatrexate is a high-affinity DHFR inhibitor targeting RFC-1, used in cancer treatment and immunosuppression.</p>Formule :C23H23N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.47Antibacterial synergist 1
<p>Compound 20P is a potent antibacterial, inhibits biofilms with IC50 4.5 μM, and reduces pyocyanin at IC50 8.6 μM.</p>Formule :C19H24N2O4Couleur et forme :SolidMasse moléculaire :344.4(R)-ZG197
<p>(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.</p>Formule :C28H35F3N4O3Couleur et forme :SolidMasse moléculaire :532.6GSK5852
<p>GSK5852, an HCV NS5B inhibitor, has IC50 of 50 nM; potently fights HCV with EC50 of 3.0 nM for GT1a and 1.7 nM for GT1b.</p>Formule :C27H27BF2N2O6SCouleur et forme :SolidMasse moléculaire :556.3911-Oxahomoaminopterin
CAS :<p>11-Oxahomoaminopterin exhibits antifolate activity against two folate-requiring microorganisms and inhibited Lactobacillus casei DHFR.</p>Formule :C20H21N7O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.42AZD-3199 dihydrobromide
CAS :<p>AZD-3199 dihydrobromide is a β2 adrenergic receptor agonist potentially for the treatment of asthma and chronic obstructive.</p>Formule :C32H44Br2N4O4SCouleur et forme :SolidMasse moléculaire :740.59OP-5244 sodium
<p>OP-5244 sodium: potent oral CD73 inhibitor (IC50: 0.25 nM), potential in cancer research by hindering adenosine, reversing immunosuppression.</p>Formule :C19H28ClN5NaO9PCouleur et forme :SolidMasse moléculaire :559.87BRD0418
CAS :<p>BRD0418 acts as an upregulator of TRIB1 expression by leading to reprogramming of hepatic lipoprotein metabolism from adipogenesis to clearance it.</p>Formule :C29H32N2O5Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :488.57MsbA-IN-1
<p>MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.</p>Formule :C23H18Cl2FNO3Couleur et forme :SolidMasse moléculaire :446.3BCL6-IN-9
CAS :<p>BCL6-IN-9 (compound 1) is a potent inhibitor of B-cell lymphoma 6 protein (BCL6) (IC50: 3.9 nM) and can be used to study cancer.</p>Formule :C22H18ClF2N5O2Couleur et forme :SolidMasse moléculaire :457.86CAII-IN-2
<p>CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.</p>Formule :C18H19BrN4SCouleur et forme :SolidMasse moléculaire :403.34BMS-248360
CAS :<p>BMS-248360: Oral dual hAT1/hETA antagonist with Kis of 10nM & 1.9nM, respectively; treats hypertension.</p>Formule :C36H45N5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :659.84SS-RJW100
<p>SS-RJW100 is an enantiomer of RJW100 targeting LRH-1, SF-1, enhances Tif2 interaction, and disrupts LRH-1 networks with lowered stability.</p>Formule :C28H34OCouleur et forme :SolidMasse moléculaire :386.57CH5447240
CAS :<p>CH5447240: potent hPTHR1 agonist, treats Hypoparathyroidism, EC50 12 nM, 55% oral bioavailability, raises rat serum calcium.</p>Formule :C26H39N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :517.68Squalamine
CAS :<p>Squalamine is an aminosterol compound, with potent broad spectrum antiviral activity.</p>Formule :C34H65N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :627.96DSM705 hydrochloride
<p>DSM705 hydrochloride: potent antimalarial, pyrrole-based DHODH inhibitor effective against Plasmodium, non-toxic to mammalian DHODH.</p>Formule :C19H20ClF3N6OCouleur et forme :SolidMasse moléculaire :440.85Streptothricin F
CAS :<p>Streptothricin F is a biochemical.</p>Formule :C19H34N8O8Couleur et forme :SolidMasse moléculaire :502.52Pyrromycin
CAS :<p>Pyrromycin is a monosaccharide anthracycline which can be used to inhibit cellular RNA synthesis.</p>Formule :C30H35NO11Couleur et forme :SolidMasse moléculaire :585.60KUS121
CAS :<p>KUS121: VCP ATPase activity inhibitor (IC50=330 nM), protects cells from ER stress, assists in cerebral ischemia, and preserves vision in retinitis pigmentosa.</p>Formule :C22H17FN4NaO3SCouleur et forme :SolidMasse moléculaire :459.45Lumirubin
CAS :<p>Lumirubin is a water-soluble photoproduct of bilirubin formed in vivo during phototherapy.</p>Formule :C33H36N4O6Couleur et forme :SolidMasse moléculaire :584.66Elacestrant S enantiomer dihydrochloride
<p>Elacestrant (RAD1901) dihydrochloride, an oral ERR degrader, has IC50 of 48 nM (ERα) and 870 nM (ERβ). Its S enantiomer has low activity.</p>Formule :C30H40Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :531.56LY 254155
CAS :<p>LY 254155, an antifolate,binds to mFBP and inhibits hGARFT with Kis of 1.7±0.1 and 2.1±0.2 nM, respectively.</p>Formule :C19H23N5O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :449.48Onalespib lactate
CAS :<p>Onalespib lactate is a second-generation, potent and selective HSP90 Inhibitor with antitumor activity.</p>Formule :C27H37N3O6Couleur et forme :SolidMasse moléculaire :499.6Antibacterial agent 76
<p>Antibacterial agent 76 (compound 9) is a potent antibacterial agent.</p>Formule :C23H27N3O2SCouleur et forme :SolidMasse moléculaire :409.54Encephalitic alphavirus-IN-1
<p>Alphavirus-IN-1 blocks VEEV (EC50: 0.24 μM) & EEEV (EC50: 0.16 μM), non-toxic, stable in mice plasma.</p>Formule :C27H25FN6O2Couleur et forme :SolidMasse moléculaire :484.52Anticancer agent 26
<p>Anticancer agent 26 is a promising candidate for cancer therapy and deserves further development.</p>Formule :C28H33NO5Couleur et forme :SolidMasse moléculaire :463.57GDC-6036-NH
CAS :<p>GDC-6036-NH is a precursor of compound 17a /b, which is a RAS inhibitor that can be used in cancer research.</p>Formule :C26H30ClF4N7ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :568.01DIDS
CAS :<p>DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.</p>Formule :C16H10N2O6S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.52SD-2590 HCl
CAS :<p>SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.</p>Formule :C22H26ClF3N2O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :554.96Thalicarpine
CAS :<p>Thalicarpine, a natural anticancer alkaloid, inhibits p-glycoprotein and induces DNA damage, arresting cell cycle.</p>Formule :C41H48N2O8Couleur et forme :SolidMasse moléculaire :696.83Ribocil-C R enantiomer
<p>Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective bacterial riboflavin riboswitches inhibitor.</p>Formule :C21H21N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.5Lapaquistat
CAS :<p>Lapaquistat: active TAK-475 metabolite; reduces cholesterol synthesis and statin myotoxicity.</p>Formule :C31H39ClN2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.1SCH-1473759
CAS :<p>SCH-1473759 is an inhibitor of the aurora (IC50s: 4 and 13 nM for Aurora A and B, respectively).</p>Formule :C20H26N8OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.54PF-03715455
CAS :<p>PF-03715455 is a potent p38 MAPK inhibitor, reducing TNFα in blood (IC50=1.7 nM) with selectivity for p38α, and may treat COPD.</p>Formule :C35H34ClN7O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :700.27Atorvastatin 3-Deoxyhept-2E-Enoic Acid
CAS :<p>Atorvastatin 3-Deoxyhept-2E-Enoic Acid, an impurity in Atorvastatin, lowers blood lipids as an HMG-CoA reductase inhibitor.</p>Formule :C33H33FN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.62(R)-ONO-2952
<p>(R)-ONO-2952 is the R-enantiomer of ONO-2952. ONO-2952 is selective and oral effective TSPO antagonist, with Kis of 0.330-9.30 nM inhibiting rat and human TSPO.</p>Formule :C22H20ClFN2O2Couleur et forme :SolidMasse moléculaire :398.86AChE-IN-11
<p>AChE-IN-11 aids Alzheimer's research, has neuroprotection/antioxidant properties (ORAC=2.5), and acts on AChE, MAO-B, BACE1 with IC50 values of 7.9-9.9 μM.</p>Formule :C18H28N2O4Couleur et forme :SolidMasse moléculaire :336.43Tubulin polymerization-IN-9
CAS :<p>Tubulin-IN-9 inhibits tubulin (IC50: 1.82 μM), halts K562 cells in G2/M, induces apoptosis, and has anti-cancer effects.</p>Formule :C19H19NO5SeCouleur et forme :SolidMasse moléculaire :420.32C108297
CAS :<p>C108297: glucocorticoid modulator, combats diet obesity/inflammation, reduces appetite/lipid storage, boosts fat burn.</p>Formule :C30H36FN3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.69AY 17,605
CAS :<p>AY 17,605 is an inhibitor of bovine heart and rat brain nucleoside-3',5'- monophosphate phosphodiesterase.</p>Formule :C25H36O5Couleur et forme :SolidMasse moléculaire :416.55Glutamate-5-kinase-IN-1
<p>Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.</p>Formule :C20H18N2OCouleur et forme :SolidMasse moléculaire :302.37RORγt modulator 5
CAS :<p>RORγt modulator 5, a potent RORγt modulator, exhibits a dissociation constant (K_i) of <100 nM.</p>Formule :C27H22F5N3O6SCouleur et forme :SolidMasse moléculaire :611.54(3S,4R)-Tofacitinib
CAS :<p>(3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).</p>Formule :C16H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.37Scytonemin
CAS :<p>Scytonemin, a cyanobacterial pigment, inhibits cancer cell growth by decreasing Plk1 activity, especially effective on U266 myeloma cells.</p>Formule :C36H20N2O4Couleur et forme :SolidMasse moléculaire :544.55U91356
CAS :<p>U91356 is an agonist of the dopamine receptors.</p>Formule :C13H17N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.29Cryptopleurine
CAS :<p>Cryptopleurine is an inhibitor of gene products associated with cell proliferation, survival, invasion and angiogenesis. It acts by targeting the NF-κB pathway.</p>Formule :C24H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48RET-IN-11
<p>RET-IN-11 selectively inhibits RET (IC50: 6.20 nM), promotes apoptosis, and hinders cell proliferation and migration.</p>Formule :C27H30FN9OCouleur et forme :SolidMasse moléculaire :515.59DC1SMe
CAS :<p>DC1, a CC-1065-like ADC cytotoxin, is used in cancer-targeting antibody-drug conjugates. DC1Sme, a derivative, has IC50s: 22-250 pm in various cancer cells.</p>Formule :C35H30ClN5O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :684.23COX-2-IN-9
<p>COX-2-IN-9: potent oral COX-2 blocker, selective over Celecoxib, IC50 10.17 μM, less ulcers, strong anti-inflammatory.</p>Formule :C25H23N5O4S2Couleur et forme :SolidMasse moléculaire :521.61LY 541850
CAS :<p>LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human</p>Formule :C9H13NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :199.2(S)-MALT1-IN-5
CAS :<p>(S)-MALT1-IN-5: Potent MALT1 protease inhibitor, may help in abnormal T/B-cell signalling and MALT1-linked diseases.</p>Formule :C17H17ClF2N6O3Couleur et forme :SolidMasse moléculaire :426.80UAWJ9-36-1
CAS :<p>UAWJ9-36-1: potent broad-spectrum coronavirus Protease inhibitor; IC50 = 51 nM.</p>Formule :C23H29N3O5Couleur et forme :SolidMasse moléculaire :427.49MIF2-IN-1
<p>MIF2-IN-1, potent inhibitor of MIF2 (IC50: 1μM), halts non-small cell lung cancer growth via MAPK pathway.</p>Formule :C26H19F3N2O2SCouleur et forme :SolidMasse moléculaire :480.5Iroxanadine hydrobromide
CAS :<p>Iroxanadine hydrobromide is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.</p>Formule :C14H21BrN4OCouleur et forme :SolidMasse moléculaire :341.25SHP2 IN-1
CAS :<p>SHP2 IN-1 is an allergic SHP2 (PTPN11) inhibitor(IC50 : 3 nM).</p>Formule :C18H22Cl2N6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.38ER272
CAS :<p>ER272 is a natural PKC activator, inducing hippocampal neurogenesis.</p>Formule :C24H34O6Couleur et forme :SolidMasse moléculaire :418.52Tezampanel hydrate
CAS :<p>Tezampanel is used for the treatment of migraine, neuropathic pain.</p>Formule :C13H23N5O3Couleur et forme :SolidMasse moléculaire :297.35Onfasprodil
CAS :<p>Onfasprodil, NR2B inhibitor & GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)</p>Formule :C20H23FN2O3Couleur et forme :SolidMasse moléculaire :358.41GP-1681
CAS :<p>GP-1681, a G-protein coupled receptor (GPCR) agonist, is used potentially for the treatment of influenza infection.</p>Formule :C24H30NaO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.48MA242
CAS :<p>MA242 is a nuclear factor of activated T cells 1 (NFAT1) for Pancreatic Cancer Therapy and dual inhibitor of murine double minute 2 (MDM2).</p>Formule :C26H21ClF3N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :579.98LY 235959
CAS :<p>LY 235959 is a NMDA receptor antagonist.</p>Formule :C11H20NO5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :277.25PNU-248686A
CAS :<p>PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).</p>Formule :C22H18ClNaO5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.95FLT3/ITD-IN-1
<p>FLT3/ITD-IN-1 inhibits FLT3-ITD with IC50s: 38.2 nM (FLT3) and 144.1 nM (ITD), and fights acute myeloid leukemia.</p>Formule :C19H22N6O2Couleur et forme :SolidMasse moléculaire :366.42RN941
CAS :<p>RN941 is a highly potent Bruton's tyrosine kinase (BTK) inhibitor.</p>Formule :C34H34FN7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :639.68VEGFR-2/DHFR-IN-2
<p>VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.</p>Formule :C21H21NO4Couleur et forme :SolidMasse moléculaire :351.4L2H2-6OTD
CAS :<p>L2H2-6OTD is a telomerase inhibitor with G-quadruplex loops; IC50: 15 nM.</p>Formule :C30H30N10O8Couleur et forme :SolidMasse moléculaire :658.62HSV-TK substrate
CAS :<p>HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells.</p>Formule :C11H15N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :281.27LDHA-IN-5
CAS :<p>LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primary</p>Formule :C27H22FN7O6S3Couleur et forme :SolidMasse moléculaire :655.7AXKO-0046
<p>AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.</p>Formule :C25H33N3Couleur et forme :SolidMasse moléculaire :375.55TY 11345
CAS :<p>TY 11345 is a proton pump inhibitor.</p>Formule :C18H18N3NaO2SCouleur et forme :SolidMasse moléculaire :363.41Antiangiogenic agent 2
<p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>Formule :C26H26FN3O4Couleur et forme :SolidMasse moléculaire :463.5FT001
CAS :<p>FT001: Oral BET Bromodomain inhibitor, IC50=0.46μM, suppresses MYC, anti-cancer, effective in vitro/vivo.</p>Formule :C25H29N3O4SDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :467.58SCP1-IN-1
CAS :<p>SCP1-IN-1 (SH T-62) is a potent inhibitor of SCP1, promoting REST degradation and potentially aiding glioblastoma research.</p>Formule :C20H19F3N2O7S2Degré de pureté :99.53%Couleur et forme :SoildMasse moléculaire :520.5SF0166
CAS :<p>SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.</p>Formule :C23H27F2N5O4Couleur et forme :SolidMasse moléculaire :475.49L 668750
CAS :<p>L 668750 is an inhibitor of platelet-activating factor.</p>Formule :C25H34O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :510.6F 14679
CAS :<p>F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.</p>Formule :C21H25ClF2N4ODegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :422.9CDK-IN-9
<p>CDK-IN-9: A potent CDK inhibitor, gels to enhance CDK12/DDB1 binding, targets CDK2/E (IC50: 4 nM), induces apoptosis via dephosphorylation.</p>Formule :C21H24N8SCouleur et forme :SolidMasse moléculaire :420.53BM635 hydrochloride (1493762-74-5 free base)
<p>BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).</p>Formule :C25H30ClFN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.97NITD-688
CAS :<p>NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.</p>Formule :C25H32N4O3S2Couleur et forme :SolidMasse moléculaire :500.68Lu 26-046
CAS :<p>Lu 26-046 is a muscarinic receptor agonist.</p>Formule :C10H12N2OSCouleur et forme :SolidMasse moléculaire :208.28Aβ42-IN-1
CAS :<p>Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).</p>Formule :C29H27ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :499Tubulin polymerization-IN-4
CAS :<p>Tubulin polymerization-IN-4: inhibits tubulin (IC50=4.6 μM), blocks G2/M phase, induces apoptosis, hinders cell cloning/migration, damages vasculature.</p>Formule :C21H21ClN2O4Couleur et forme :SolidMasse moléculaire :400.86(±)-ANAP hydrochloride (1185251-08-4 free base)
<p>(±)-ANAP hydrochloride is the amino acid analog of prodan. It can be used as a fluorescent probes and enhance environmental sensitivity.</p>Formule :C15H17ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.76Hsp90-IN-16
<p>Hsp90-IN-16, a selective HSP90 inhibitor, targets HER2+ cancers with 6 μM IC50 in HCC1954 cells, blocking client proteins and inducing apoptosis.</p>Formule :C30H26FN3O6Couleur et forme :SolidMasse moléculaire :543.54AMG-548 hydrochloride
<p>AMG-548 hydrochloride: orally active, p38α inhibitor (Ki=0.5 nM), 1000x less for p38γ/δ, also blocks TNFα (IC50=3 nM) & inhibits casein kinase 1 δ/ε.</p>Formule :C29H28ClN5OCouleur et forme :SolidMasse moléculaire :498.02Anti-inflammatory agent 18
<p>Anti-inflammatory agent 18: NO activity blocker (IC50: 15.94 μM), hampers HMGB1-induced inflammation, potential for COVID-19, sepsis study.</p>Formule :C30H50O6Couleur et forme :SolidMasse moléculaire :506.71Antileishmanial agent-5
<p>Antileishmanial agent-4, a ribonucleoside analogue, targets L.infantum and T.cruzi with EC50s of 0.68 μM and 0.83 μM.</p>Formule :C17H17ClN4O4Couleur et forme :SolidMasse moléculaire :376.79Murizatoclax
CAS :<p>AMG 397 is an oral MCL1 inhibitor .</p>Formule :C42H57ClN4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :765.44BAA473
<p>BAA473, a bile acid analog, activates the pyrin inflammasome, triggering IL-18 secretion in myeloid and intestinal cells.</p>Formule :C36H62O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :574.87Antibacterial agent 113
<p>Antibacterial agent 113 targets multiple bacteria including P. aeruginosa and E. coli, showing efficacy at MIC 15625 μM.</p>Formule :C29H18ClN5OCouleur et forme :SolidMasse moléculaire :487.94NVP-CGM097 sulfate
CAS :<p>NVP-CGM097 sulfate is a potent and selective inhibitor of MDM2 (hMDM2, IC50 of 1.7±0.1 nM).</p>Formule :C38H49ClN4O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :757.34WEHI-9625
CAS :<p>WEHI-9625 is a tricyclic sulfone small molecule apoptosis inhibitor (EC50: 69 nM).</p>Formule :C34H27NO5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.71BAY-899
CAS :<p>BAY-899, oral LH-R antagonist, IC50: 185 nM (hLH), 46 nM (rLH), lowers sex hormones in vivo.</p>Formule :C25H19F2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.45AM-6494
CAS :<p>AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).</p>Formule :C22H21F2N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.5
