Inhibiteurs

Questiomycin A derivatives 14 is a Questiomycin A derivative.

Arsenazo I is a calcium-sensitive, metallochromic dye used as reagent.

Melarsonyl dipotassium, also known as melarsonic acid dipotassium, is a potent anthelmintic agent with the ability to effectively inhibit parasites.

Thalidomide-NH-PEG4-Ms: cereblon ligand + linker, for PROTAC BCL-XL degrader XZ739.

Lupinine hydrochloride is a bioactive chemical.

Cap-dependent endonuclease-IN-12 (EXP-35) is a potent inhibitor with low toxicity, active against H1N1.

CYH33 methanesulfonate is a PI3Kα inhibitor with IC50 of 5.9 nM; halts breast and NSCLC cell growth, effective against solid tumors.

OVA Peptide (323-339) is an Ovalbumin epitope crucial for hypersensitivity in BALB/c mice.

MCAAD-3, a near-infrared Aβ imaging probe, exhibits blood-brain barrier permeability and strong affinity for Aβ polymers (Ki >106 nM).

Questiomycin A derivatives 12 is a Questiomycin A derivative.

Chol-N3 is a bioorthogonal chol probe capable of integrating with super-resolution fluorescence microscopy (SRM) to enable direct nanoscale imaging of lipid

PD-1/PD-L1-IN 5 is an inhibitor of PD-1/PD-L1 protein/protein interaction (IC50 of ≤100 nM).

Diacetoxyscirpenol: a fungal mycotoxin causing blood disorders in humans/animals.

HJM-561 is a potent and selective EGFR PROTAC with oral bioavailability, capable of overcoming osimertinib-resistant EGFR triple mutations and demonstrating

PROTAC MDM2 Degrader-4 targets MDM2 for degradation with E3 ligase via a linked inhibitor.

Thalidomide-based cereblon ligand-linker for selective dBRD9 synthesis, enabling BAF complex study.

Antibacterial agent 30 exhibits remarkable in vitro activity against Xoo, as evidenced by its EC50 value of 1.9 μg/mL.

Moxetumomab pasudotox (CAT 8015), an anti-CD22 immunotoxin for researching hairy cell leukemia.

(±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.

Taragarestrant (D-0502) is an oral SERD with potent activity against ER+ breast cancer.

(3,4-Dihydroxy-5-methoxybenzoyl)taraxerol is a natural products from plants

PROTAC MDM2 Degrader-1 uses PROTAC tech to break down MDM2 with an inhibitor, linker, and E3 ligase ligand.

Questiomycin A derivatives 20 is a Questiomycin A derivative.

Antiviral agent 8, surpassing lead compounds crocin-1 and crocin-2, has been identified as a potent and promising candidate with enhanced antiviral activities.

PROTAC BRD4 Degrader-16 is a potent degrader of BRD4, exhibiting IC50 values of 34.58 nM for BRD4 (BD1) and 40.23 nM for BRD4 (BD2).