Inhibiteurs

2', 3'-cGAMP-C2-SH is a ADC cytotoxin.

MCA17-1 exhibits superior bioactivity compared to the positive control, obeticholic acid (OCA), in the treatment of liver fibrosis.

Microcystin-LY, from Microcystis aeruginosa, is a heptapeptide toxin that triggers oxidative stress by activating the Nrf2 pathway, most effective at 3μM.

Patecibart is a humanized immunoglobulin G4-kappa monoclonal antibody that functions as an antagonist to the endothelin receptor A (EDNRA).

PROTAC BRD4 Degrader-16 is a potent degrader of BRD4, exhibiting IC50 values of 34.58 nM for BRD4 (BD1) and 40.23 nM for BRD4 (BD2).

ER degrader 2: Potent estrogen receptor disruptor; key for cancer research.

Compound 17h is a potent antibacterial against VRE and MRSA, reduces MRSA biofilms, and is stable in liver microsomes.

Zanamivir-cholesterol conjugate is an extended-duration neuraminidase inhibitor highly effective against drug-resistant influenza strains.

Questiomycin A derivatives 20 is a Questiomycin A derivative.

Kbz probe 1, an adaptable probe utilized for examining histone benzoylation and interactions within living cells, showcases extensive versatility.

9-Azido-Neu5DAz is a non-natural bifunctional carbohydrates as imaging agent.

Taragarestrant (D-0502) is an oral SERD with potent activity against ER+ breast cancer.