Inhibiteurs

Thalidomide-C2-amido-C2-COOH is a compound that includes a CRBN ligand for the E3 ubiquitin ligase, as well as a linker.

Compound 17h is a potent antibacterial against VRE and MRSA, reduces MRSA biofilms, and is stable in liver microsomes.

Microcystin-LY, from Microcystis aeruginosa, is a heptapeptide toxin that triggers oxidative stress by activating the Nrf2 pathway, most effective at 3μM.

PROTAC MDM2 Degrader-3 uses PROTAC tech to efficiently break down MDM2 with a potent inhibitor and E3 ligase ligand.

Thalidomide-based cereblon ligand-linker for selective dBRD9 synthesis, enabling BAF complex study.

Cap-dependent endonuclease-IN-12 (EXP-35) is a potent inhibitor with low toxicity, active against H1N1.

GEM-5, a gemcitabine conjugate with HIF-1α inhibitor YC-1 (IC50=30 nM), down-regulates HIF-1α, up-regulates p53, and induces A2780 cell apoptosis.

PROTAC MDM2 Degrader-2: A potent MDM2-targeting compound with PROTAC tech for E3 ligase-mediated degradation.

Diacetoxyscirpenol: a fungal mycotoxin causing blood disorders in humans/animals.

A031: PROTAC AR degrader, IC50 < 0.25 μM, inhibits prostate cancer growth in zebrafish.

Podoblastin A (D-mannitol) is a useful organic compound for research related to life sciences and the catalog number is TSP-41077145.