Inhibiteurs

Spiratisanin A is a natural product from Spiraea japonica.

Glabralide A is a natural product from plants

Compound 17h is a potent antibacterial against VRE and MRSA, reduces MRSA biofilms, and is stable in liver microsomes.

SH379, a 2-methylpyrimidine diterpene derivative, boosts testosterone synthesis enzymes and autophagy via AMPK/mTOR.

Ppack HCl is a peptide that binds thrombin, inhibiting platelet activation (Ki: 0.24 nM). Used as an anticoagulant and to research clotting and inflammation.

Compound 13i is a potent PROTAC BRD4 degrader with IC50s: 29.54 nM (BD1), 3.82 nM (BD2), impedes G2/M progression, and induces apoptosis in MV-4-11 cells.

Trk-IN-6 shows excellent in vitro potency on a panel of TRK mutants ( IC 50 = 0.2-0.7 nM).

2', 3'-cGAMP-C2-SH is a ADC cytotoxin.

C.I. Pigment Yellow 14 is a yellow dye.

Firefly Luciferase circRNA, originally isolated from Photinus pyralis (Firefly), expresses a luciferase protein and serves as an optimal marker for monitoring

CAY10736: Anticancer agent, blocks cell growth & migration in various cancers, effective in mouse models.

Fungicide5 is a fungicide candidate targeting succinate dehydrogenase ( K i = 0.095 μM).

PD-1/PD-L1 binder, Kd 0.51 μM; blocks interaction in flow cytometry at 1 mg/mL; inhibits tumors, extends mouse survival.