Inhibiteurs

Aflatoxin M1, a toxic metabolite of Aflatoxin B1, is produced by Aspergillus fungi, with a toxicity order: B1 > M1 > G1 > B2 > M2 > G2.

Thalidomide-C2-amido-C2-COOH is a compound that includes a CRBN ligand for the E3 ubiquitin ligase, as well as a linker.

BRD73842 is an inhibitor of Plasmodium PI4K .

Immuno-Oncology Screening Library with 90+ cancer/immunology compounds in 96-well format, 10 mM DMSO solutions, including various target modulators.

PD-1/PD-L1-IN 5 is an inhibitor of PD-1/PD-L1 protein/protein interaction (IC50 of ≤100 nM).

Chol-N3 is a bioorthogonal chol probe capable of integrating with super-resolution fluorescence microscopy (SRM) to enable direct nanoscale imaging of lipid

PROTAC MDM2 Degrader-3 uses PROTAC tech to efficiently break down MDM2 with a potent inhibitor and E3 ligase ligand.

Thalidomide-O-amido-PEG3-C2-NH2 TFA, a cereblon ligand-PEG linker for PROTAC, is synthesized.

SH379, a 2-methylpyrimidine diterpene derivative, boosts testosterone synthesis enzymes and autophagy via AMPK/mTOR.

CAY10735: Anticancer agent; inhibits growth/migration in various cancer cells; reduces tumor in mouse models. IC50=0.674-11.56μM.

Ppack HCl is a peptide that binds thrombin, inhibiting platelet activation (Ki: 0.24 nM). Used as an anticoagulant and to research clotting and inflammation.

Antibacterial agent 30 exhibits remarkable in vitro activity against Xoo, as evidenced by its EC50 value of 1.9 μg/mL.