Inhibiteurs de la réabsorption de la sérotonine et de la norépinéphrine (IRSN)
Les inhibiteurs de la recapture de la sérotonine-noradrénaline (IRSN) sont une classe de composés qui inhibent la recapture des neurotransmetteurs sérotonine et noradrénaline, augmentant ainsi leurs niveaux dans la fente synaptique. Cette action améliore la neurotransmission et est couramment utilisée dans le traitement de la dépression, de l'anxiété et de la douleur chronique. Les IRSN sont des outils essentiels pour étudier les troubles de l'humeur et le développement de thérapies antidépressives. Chez CymitQuimica, nous proposons une sélection d'IRSN pour soutenir vos recherches en psychopharmacologie, troubles de l'humeur et neurobiologie.
428 produits trouvés pour "Inhibiteurs de la réabsorption de la sérotonine et de la norépinéphrine (IRSN)"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
N,N-Didesmethyl Sibutramine HCl
CAS :Formule :C15H22ClN·HClCouleur et forme :White To Off-White SolidMasse moléculaire :251.80 36.46Atomoxetine EP Impurity G DiHCl (Mixture of Diastereomers)
CAS :Formule :C27H34N2O2·2HClCouleur et forme :White To Off-White SolidMasse moléculaire :418.58 2*36.46Desvenlafaxine Succinate (O-Desmethyl Venlafaxine Succinate)
CAS :Formule :C16H25NO2·C4H6O4Couleur et forme :White To Off-White SolidMasse moléculaire :263.38 118.09N-Desethyl L-Milnacipran HCl
Formule :C13H18N2O·HClCouleur et forme :Off-White SolidMasse moléculaire :218.30 36.465-Hydroxy-6-Methoxy Duloxetine Sulfate-d3 Triethylamine Salt
Formule :C19H18D3NO6S2·Et3NMasse moléculaire :426.52 101.19Duloxetine
CAS :<p>Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.</p>Formule :C18H19NOSDegré de pureté :99.71% - 99.89%Couleur et forme :SolidMasse moléculaire :297.41N,O-Didesmethyl Venlafaxine-13C-d3 ( (Mixture of Diastereomers)
Formule :C1413CH20D3NO2Masse moléculaire :253.36Venlafaxine EP Impurity D-13C-d3 HCl (Venlafaxine USP Related Compound A-13C-d3, N-Desmethyl Venlafaxine-13C-d3 HCl)
CAS :Formule :C1513CH22D3NO2·HClMasse moléculaire :267.39 36.46Venlafaxine Related Compound 4 (S-4-(1-(1-Hydroxycyclohexyl)-2-((4-hydroxyphenylethyl) amino) ethyl) phenol)
Formule :C22H29NO3Masse moléculaire :355.48rac-Duloxetine Oxalate
CAS :Formule :C18H19NOS·C2H2O4Couleur et forme :Off-White SolidMasse moléculaire :297.42 90.03Milnacipran Impurity 31
CAS :Formule :C11H10O2Couleur et forme :White To Off-White SolidMasse moléculaire :174.20Venlafaxine
CAS :<p>Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD),</p>Formule :C17H27NO2Degré de pureté :99.2%Couleur et forme :White Solid CrystallineMasse moléculaire :277.4N-Nitroso Atomoxetine EP Impurity B (N-Nitroso (S)-Atomoxetine)
Formule :C17H20N2O2Masse moléculaire :284.36Milnacipran
CAS :<p>Milnacipran, an SNRI with 85% bioavailability, treats fibromyalgia and is well absorbed orally.</p>Formule :C15H22N2OCouleur et forme :SolidMasse moléculaire :246.355-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane Hydrochloride
CAS :Produit contrôlé<p>Impurity Venlafaxine EP Impurity E<br>Applications 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane Hydrochloride (Venlafaxine EP Impurity E) is a useful building block in the synthesis of various pharmaceuticals.<br></p>Formule :C17H25NO2·ClHCouleur et forme :Beige To Light YellowMasse moléculaire :311.85ent Atomoxetine-d3, Hydrochloride
CAS :Produit contrôléFormule :C17H19D3ClNOCouleur et forme :NeatMasse moléculaire :294.83N-Nitroso Duloxetine
CAS :Formule :C18H18N2O2SCouleur et forme :Colourless To Light YellowMasse moléculaire :326.413Dehydro Venlafaxine
CAS :Produit contrôléFormule :C17H25NOCouleur et forme :NeatMasse moléculaire :259.39N-Nitroso Rac N-Desmethyl Tramadol
Formule :C15H22N2O3Couleur et forme :Colourless To Light YellowMasse moléculaire :278.347(E)-N-Methylcinnamylamine Hydrochloride
CAS :Produit contrôlé<p>Applications (E)-N-Methylcinnamylamine is an 3-amino-1-phenyl-prop-1-ene derivative with potential to inhibit and inactivate monoamine oxidase.<br>References Williams, C.H. et al.: Biochim. Biophys. Acta Prot. Struc. Mol. Enzymol., 119, 111 (1992);<br></p>Formule :C10H14ClNCouleur et forme :NeatMasse moléculaire :183.68Ethyl α-(p-Methoxyphenyl)-β-(dimethylamino)propionate
CAS :<p>Impurity Venlafaxine EP Impurity B<br>Applications Ethyl α-(p-Methoxyphenyl)-β-(dimethylamino)propionate (Venlafaxine EP Impurity B) is an impurity of Venlafaxine (impurity B).<br></p>Formule :C14H21NO3Couleur et forme :NeatMasse moléculaire :251.32rac,trans-Milnacipran Hydrochloride
CAS :Produit contrôlé<p>Applications rac,trans-Milnacipran Hydrochloride is an impurity of rac-Milnacipran Hydrochloride (M344600), an antidepressant and a selective norepinephrine and serotonin reuptake inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Moret, C., et al.: Neuropharmacology, 24, 1211 (1985), Palmier, C., et al.: Eur. J. Clin. Pharmacol., 37, 235 (1989), Spencer, C.M., et al.: Drugs, 56, 405 (1998)<br></p>Formule :C15H23ClN2OCouleur et forme :NeatMasse moléculaire :282.811-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride(rac N-Desmethyl Venlafaxine Hydrochloride)
CAS :<p>Impurity Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A<br>Applications 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride (Venlafaxine EP Impurity D; Venlafaxine USP Related Compound A) is a metabolite of Venlafaxine (V120000), which is a selective serotonin noradrenaline reuptake inhibitor, used as an antidepressant.<br>References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000);<br></p>Formule :C16H25NO2·ClHCouleur et forme :WhiteMasse moléculaire :299.84(±)-Sibutramine
CAS :Produit contrôlé<p>Applications (±)-Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.<br>References Hanotin, C., et al.: Int. J. Obesity, 22, 32 (1998)<br></p>Formule :C17H26ClNCouleur et forme :Off White SolidMasse moléculaire :279.85Hordenine
CAS :<p>Applications A phenethylamine alkaloid with antibacterial and antibiotic properties found mainly in plants from the cactaceae family. It showed effects similar to Cytosine (C998950) and acted as a depressant on the central nervous system (CNS) during animal testing.<br>References Aliev, K.U. et al.: Med. Zhur. Uzbek., 8, 71 (1966); Ghosal, S. et al. Planta Medica, 22, 434 (1972); Starha, R. et al.: Biochem. Sys. Ecol., 27, 839 (1999);<br></p>Formule :C10H15NOCouleur et forme :Light Yellow SolidMasse moléculaire :165.23(-)-O-Desmethyl Tramadol
CAS :Produit contrôlé<p>Applications A optically active metabolite of Tramadol.<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formule :C15H23NO2Couleur et forme :White To Off-WhiteMasse moléculaire :249.35Sibutramine, Hydrochloride Monohydrate
CAS :Produit contrôléFormule :C17H26ClN·ClH·H2OCouleur et forme :Off White SolidMasse moléculaire :334.32(R)-3-Chloro-1-phenyl-1-(2-methylphenoxy)propane
CAS :Produit contrôléFormule :C16H17ClOCouleur et forme :NeatMasse moléculaire :260.76N-Nitroso-Atomoxetine
Produit contrôléFormule :C17H20N2O2Couleur et forme :Off WhiteMasse moléculaire :284.353D,L-Venlafaxine-d6
CAS :Produit contrôléFormule :C17H21D6NO2Couleur et forme :Off-WhiteMasse moléculaire :283.44(-)-N,N-Bisdesmethyl Tramadol
CAS :Produit contrôlé<p>Applications A optically active metabolite of Tramadol.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lintz, V.W., et al.: Arzneim.-Forsch./Drug Res., 31, II, 11, 1932 (1981)<br></p>Formule :C14H21NO2Couleur et forme :NeatMasse moléculaire :235.32(-)-Tramadol Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications An analgesic. Used in the treatment of urinary incontinence.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Raffa, R.B., et al.: J. Pharmacol. Exp. Ther., 267, 331 (1993)<br></p>Formule :C16H25NO2·ClHCouleur et forme :NeatMasse moléculaire :299.84Desmethyl Sibutramine
CAS :Produit contrôlé<p>Applications Desmethyl Sibutramine is a metabolite of Sibutramine (S422500), a serotonin and noradrenaline reuptake inhibitor (SNR). Decreases calorie intake and increases energy expenditure.<br>References Hanotin, C., et al.: Int. J. Obesity, 22, 32 (1998); Woolard, J., et al.: J. Pharmacol. Exp. Ther., 308, 1102 (2004); Geranton, S., et al.: Neuropharmacol., 46, 511 (2004)<br></p>Formule :C16H24ClNCouleur et forme :Colourless To YellowMasse moléculaire :265.82(±)-Venlafaxine-d6 Hydrochloride (N,N-dimethyl-d6)
CAS :Produit contrôlé<p>Applications (±)-Venlafaxine-d6 HCl (N,N-dimethyl-d6) (CAS# 1062606-12-5) is a useful isotopically labeled research compound.<br></p>Formule :C172H6H21NO2·ClHCouleur et forme :NeatMasse moléculaire :319.90D,L-Venlafaxine
CAS :Produit contrôlé<p>Applications A selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant.<br>References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000)<br></p>Formule :C17H27NO2Couleur et forme :White To Off-WhiteMasse moléculaire :277.40rac N-Methyl Atomoxetine Oxalate
CAS :<p>Applications rac N-Methyl Atomoxetine Oxalate is a derivative of Atomoxetine which acts as a norepinephrine reuptake inhibitor.<br>References Farid, N.A., et al.: J. Clin. Pharmacol., 25, 296 (1985), Gehlert, D.R., et al.: J. Neurochem., 64, 2792 (1995), Hwamg. et al.: Neurosci. Lett., 265, 151 (1999), Ring, B.J., et al.: Drug Metab. Dispos., 30, 319 (2002),<br></p>Formule :C18H23NO·C2H2O4Couleur et forme :Off White SolidMasse moléculaire :359.42D,L-Venlafaxine-d11 Hydrochloride (Major)
CAS :Produit contrôlé<p>Applications D,L-Venlafaxine-d10 Hydrochloride is the labeled analogue of D,L-Venlafaxine Hydrochloride (V120000), a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant.<br>References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992); Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000)<br></p>Formule :C17H17D11ClNO2Couleur et forme :Off White SolidMasse moléculaire :324.93Desmethyl Atomoxetine Hydrochloride
CAS :Produit contrôléFormule :C16H20ClNOCouleur et forme :Off-WhiteMasse moléculaire :277.79(S)-Duloxetine succinamide
CAS :<p>Duloxetine succinamide is a chromatographic, solid, acidic compound. It has been synthesized by reacting (S)-duloxetine hydrochloride with succinic anhydride in the presence of triethylamine and acetonitrile. The reaction mixture was purified by high-performance liquid chromatography to produce the desired product. The purity of the compound was confirmed by postulating that it should have a reversed-phase HPLC profile similar to that of duloxetine succinate. Duloxetine succinamide is not soluble in water and is insoluble in organic solvents such as acetone, chloroform, ether, or benzene. The compound is stable at room temperature but decomposes when heated at higher temperatures.<br>!--</p>Formule :C22H23NO4SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :397.49 g/molN,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate
CAS :<p>N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate (DMNPA) is a synthetic compound with the molecular formula C14H17NO. DMNPA is used as an analytical reference standard for the quantification of N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2thienyl) propanamine HCl by HPLC. DMNPA has been shown to be a metabolite of the drug product, where it is formed from oxidation of the parent drug.</p>Formule :C19H21NOS·C4H6O6Degré de pureté :Min. 95%Masse moléculaire :461.53 g/molN-Methyl-3-(1-naphthalenyloxy)-3-(3-thienyl) propanamine tartrate
<p>N-Methyl-3-(1-naphthalenyloxy)-3-(3-thienyl) propanamine tartrate is an impurity standard used for the quantitative analysis of norephedrine in pharmaceutical products. It is also a metabolite of methamphetamine, which has been shown to have anti-inflammatory activities.</p>Formule :C18H19NOS·C4H6O6Degré de pureté :Min. 95%Masse moléculaire :447.5 g/mol3-(Dimethylamino)-1-(3-thienyl)propan-1-ol
CAS :<p>3-(Dimethylamino)-1-(3-thienyl)propan-1-ol (DMAT) is an impurity that was identified in a drug product and that is not found in the natural form. DMAT is an intermediate of the synthesis of DMH, which is used as a research and development tool. DMAT has been shown to be metabolized by cytochrome P450 enzymes and other oxidative reactions, such as oxidation by cytochrome P450 enzymes or conjugation with glucuronic acid. DMAT also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>Formule :C9H15NOSDegré de pureté :Min. 95%Couleur et forme :White to yellow solid.Masse moléculaire :185.29 g/molEthyl 3-(dimethylamino)-2-(4-methoxyphenyl)propanoate
CAS :<p>Ethyl 3-(dimethylamino)-2-(4-methoxyphenyl)propanoate is an impurity standard for drug product. It is a high purity, API impurity, HPLC standard and niche chemical that is found in the CAS No. 323176-93-8. This compound is used in drug development and analytical research. It is a synthetic compound that can be custom synthesized, natural or found in research and development.</p>Formule :C14H21NO3Degré de pureté :(%) Min. 95%Couleur et forme :Clear Viscous LiquidMasse moléculaire :251.32 g/mol2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene
CAS :<p>2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene is a synthetic compound that has been used as an impurity standard for the drug product and API. It has also been used for the pharmacopoeia, research and development, and analytical purposes. This compound is a metabolite of erythromycin.</p>Formule :C18H19NOSDegré de pureté :Min. 95%Couleur et forme :White To Pink Or Yellow SolidMasse moléculaire :297.42 g/molN-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride
CAS :<p>N-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride is a custom synthesis that has been shown to be a metabolite of naphthalene. It has been used as an impurity standard for N-methyl-3-(4-naphthol)-2-[(5-nitrofuran-2-yl)methyl] propanamine and in metabolism studies.</p>Formule :C18H19NOS•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :333.88 g/mol4-Methoxy-N,N-dimethyl-phenethylamine
CAS :Produit contrôlé<p>4-Methoxy-N,N-dimethylphenethylamine is a natural product that has been shown to inhibit the transfer of bacteria from the environment to food. It also has regulatory properties and can be used as a supplement in dietary drinks. 4-Methoxy-N,N-dimethylphenethylamine is an alkaloidal extract and has been shown to have antibacterial activity against Escherichia coli, Salmonella enterica, and Listeria monocytogenes. This compound was also found to have diffraction properties, which are related to its ability to bind DNA in bacterial cells.</p>Formule :C11H17NODegré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :179.26 g/molN-Desethyl Milnacipran-d5
CAS :Produit contrôlé<p>Applications A labelled metabolite of Milnacipran.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bonnaud, B., et al.: J. Med. Chem., 30, 318 (1987), Kazuta, Y., et al.: Bioorg. Med. Chem., 10, 3829 (2002), Iversen, L., et al.: Br. J. Pharmacol., 147, S82 (2006),<br></p>Formule :C13H13D5N2OCouleur et forme :NeatMasse moléculaire :223.33
![5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane Hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM265975.webp&w=3840&q=75)
![1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]cyclohexanol Hydrochloride(rac N-Desmethyl Venlafaxine…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM266250.webp&w=3840&q=75)
