Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65615 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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2-Des(acetylthiomethyl)-2-methylene Racecadotril
CAS :Produit contrôlé<p>Applications An impurity of the antidiarrheal Racecadotril (R070600).<br>References Reddy, K.M. et al.: Pharmazie, 61, 994 (2006);<br></p>Formule :C19H19NO3Couleur et forme :NeatMasse moléculaire :309.36Nor Mianserin
CAS :Produit contrôlé<p>Applications The active metabolites of Miansein (M341500) in plasma, an antidepressant.<br>References Kent, J., et al.: Lancet, 355, 911 (2000), Maurer, H., et al.: Ther. Drug Monit., 24, 117 (2002),<br></p>Formule :C17H18N2Couleur et forme :NeatMasse moléculaire :250.34Eltenac
CAS :<p>Applications Eltenac is a nonsteroidal anti-inflammatory drug.<br>References Allen, A., et al.: Gut, 21, 249 (1980), Tobin, T., et al.: J. Vet. Pharmacol. Therap., 9, 1 (1986),<br></p>Formule :C12H9Cl2NO2SCouleur et forme :NeatMasse moléculaire :302.181-(4-Hydroxy-3-methoxyphenyl)-1-propanone
CAS :<p>Applications 1-(4-Hydroxy-3-methoxyphenyl)-1-propanone is a derivative of Guaiacol, a precursor to various flavorants, such as eugenol and vanillin.<br>References Allen, C., et al.: Org. Synth., 3, 418 (1955); Esposito, L., et al.: Kirk-Othmer Encyclopedia of Chemical Technology, 4th edition, 24, 812 (1997)<br></p>Formule :C10H12O3Couleur et forme :NeatMasse moléculaire :180.20Riluzole 5-Trifluoromethoxy Isomer
CAS :Produit contrôlé<p>Stability Toxic<br>Applications Riluzole 5-Trifluoromethoxy Isomer is an impurity of Riluzole (R510000); a neuroprotective agent. Riluzole modulates glutamatergic transmission. It is a glutamate release inhibitor and an anticonvulsant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gunakkunru, A., et al.: Asian J. Chem., 19, 2843 (2007); Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985); Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993); Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Formule :C8H5F3N2OSCouleur et forme :NeatMasse moléculaire :234.21-Chloro Dihydro Dutasteride
CAS :<p>Impurity Dutasteride EP Impurity F<br>Applications 1-Chloro Dihydro Dutasteride (Dutateride EP Impurity F) is a 3-oxo-4-aza-5α-androstene-17β-carboxylic acid derivative and an impurity of Dutasteride (D735000).<br></p>Formule :C27H31ClF6N2O2Couleur et forme :NeatMasse moléculaire :564.99Omeprazole Sulfide
CAS :Produit contrôléFormule :C17H19N3O2SCouleur et forme :White To Light BrownMasse moléculaire :329.423-(1,3-benzodioxol-5-yl)-1-methyl-1{H}-pyrazole-5-carboxylic acid
CAS :Degré de pureté :95.0%Masse moléculaire :246.2220001220703rac Carprofen
CAS :Produit contrôléFormule :C15H12ClNO2Couleur et forme :NeatMasse moléculaire :273.713,3-Pentamethylene Glutarimide
CAS :Produit contrôlé<p>Applications Gabapentin intermediate.<br>References Leonardi, A., et al.: J. Med. Chem., 47, 1900 (2004),<br></p>Formule :C10H15NO2Couleur et forme :NeatMasse moléculaire :181.23N-(2-Propynyl)-2,3-dihydroinden-1-amine
CAS :Produit contrôlé<p>Applications N-(2-PROPYNYL)-2,3-DIHYDROINDEN-1-AMINE (cas# 1875-50-9) is a useful research chemical.<br></p>Formule :C12H13NCouleur et forme :Dark YellowMasse moléculaire :171.238Phenylephrone Hydrochloride
CAS :<p>Impurity Phenylephrine EP Impurity C; Phenylephrine USP Related Compound C (1-(3-Hydroxyphenyl)-2-(methylamin<br>Applications Phenylephrine Hydrochloride (Phenylephrine EP Impurity C; Phenylephrine USP Related Compound C (1-(3-Hydroxyphenyl)-2-(methylamino)ethan-1-one Hydrochloride)) is an impurity C of Phenylephrine.<br>References Bodor, N., et al.: J. Med. Chem., 31, 100 (1988), Goskonda, V., et al.: J. Pharm. Sci., 88, 180 (1999),<br></p>Formule :C9H11NO2·ClHCouleur et forme :Off-White To BeigeMasse moléculaire :201.65Propylthiouracil-d5
CAS :Produit contrôlé<p>Applications Labelled antihyperthyroid. Has been used to promote fattening. This substance is reasonably anticipated to be a human carcinogen.<br>References Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 6, 457 (1977), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984),<br></p>Formule :C7H5D5N2OSCouleur et forme :Off-WhiteMasse moléculaire :175.26Prothioconazole
CAS :<p>Applications Prothioconazole is an antifungal metabolite used in agricultural fungicides and herbicides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Aristimuno Ficoseco, M.E., et al.: Nat. Prod. Res (2016);<br></p>Formule :C14H15Cl2N3OSCouleur et forme :NeatMasse moléculaire :344.26rac N-Methyl Atomoxetine Oxalate
CAS :<p>Applications rac N-Methyl Atomoxetine Oxalate is a derivative of Atomoxetine which acts as a norepinephrine reuptake inhibitor.<br>References Farid, N.A., et al.: J. Clin. Pharmacol., 25, 296 (1985), Gehlert, D.R., et al.: J. Neurochem., 64, 2792 (1995), Hwamg. et al.: Neurosci. Lett., 265, 151 (1999), Ring, B.J., et al.: Drug Metab. Dispos., 30, 319 (2002),<br></p>Formule :C18H23NO·C2H2O4Couleur et forme :Off White SolidMasse moléculaire :359.422-(Pyridin-2-yl)-4H-benzo[e][1,3]thiazin-4-one
CAS :Degré de pureté :97.0%Masse moléculaire :240.27999877929688Ref: 10-F547198
5mgÀ demander10mgÀ demander25mgÀ demander50mgÀ demander100mgÀ demander250mgÀ demanderMethyl 2-Sulfamoylbenzoate
CAS :<p>Applications Methyl 2-Sulfamoylbenzoate is a building block used in various synthetic preparations. It is also classified as a pollutant found in a municipal wastewater treatment plant.<br>References Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009);<br></p>Formule :C8H9NO4SCouleur et forme :NeatMasse moléculaire :215.23Ritonavir-13C3
CAS :Produit contrôlé<p>Applications A stable labelled selective HIV protease inhibitor Ritonavir (R535000). It is a COVID19-related research product.<br>References Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994), Ammaranond, P., et al.: J. Clin. Virol., 26, 153(2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788 (2006)<br></p>Formule :C3C34H48N6O5S2Couleur et forme :NeatMasse moléculaire :723.92Amisulpride-d5
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Labelled Amisulpride (A633250). Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985), Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997),<br></p>Formule :C17D5H22N3O4SCouleur et forme :Off White SolidMasse moléculaire :374.51Desacetyl Triflusal
CAS :<p>Applications The active metabolite of Triflusal; inhibits cardiac hypertrophy in vitro and in vivo by blocking the NF-κB signaling pathway.<br>References Bayon, Y., et al.: Br. J. Pharmacol., 126, 1359 (1999), Cabrero, A., et al.: Diabetes, 50, 1883 (2001), Cabrero, A., et al.: J. Biol. Chem., 277, 10100 (2002), Culebras, A., et al.: Neurology, 62, 1073 (2004),<br></p>Formule :C8H5F3O3Couleur et forme :NeatMasse moléculaire :206.121-[2-(2,4-Difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole
CAS :<p>Impurity Fluconazole EP Impurity G<br>Applications 1-[2-(2,4-Difluorophenyl)-2,3-epoxypropyl]-1H-1,2,4-triazole (Fluconazole EP Impurity G) is an epoxy impurity of the antifungal agent Fluconazole (F421000).<br>References Bourichi, H. et al.: STP Pharm. Prat., 18, 285 (2008); Dongre, V.G. et al.: J. Pharmac. Biomed. Anal., 42, 334 (2006):<br></p>Formule :C11H9F2N3OCouleur et forme :NeatMasse moléculaire :237.21(S)-Crizotinib
CAS :Produit contrôlé<p>Applications (S)-Crizotinib is the S-isomer of Crizotinib (C785000) and a novel potent, selective, and cell permeable MTH1 inhibitor. (S)-Crizotinib can also serve as a promising anticancer agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Huber, K.V.M., et al.: Nature, 508, 222 (2014)<br></p>Formule :C21H22Cl2FN5OCouleur et forme :Off-White To Light YellowMasse moléculaire :450.34NN'-Bis(2-hydroxyethyl)urea
CAS :<p>Applications NN'-Bis(2-hydroxyethyl)urea (cas# 15438-70-7) is a useful research chemical.<br></p>Formule :C5H12N2O3Couleur et forme :NeatMasse moléculaire :148.16Quinoline Yellow (Technical Grade)
CAS :<p>Stability Hygroscopic<br>Applications Quinoline yellow, is a yellow powder used in lipstick, lotion, soap, shampoo, bubble bath, ingested drugs, and applied drugs applications.<br></p>Formule :C18H9NNa2O8S2Couleur et forme :NeatMasse moléculaire :477.384-Amino-N-(1,1-dimethylethyl)-4,5-dihydro-3-(1-methylethyl)-5-oxo-1H-1,2,4-triazole-1-carboxamide
CAS :Produit contrôlé<p>Applications 4-Amino-N-(1,1-dimethylethyl)-4,5-dihydro-3-(1-methylethyl)-5-oxo-1H-1,2,4-triazole-1-carboxamide is a triazolinone herbicide with a broad spectrum of weed control.<br>References Dayan, F., et al.: Weed Science, 57, 579 (2009); Elmore, M., et al.: Weed Technol., 27, 596 (2013)<br></p>Formule :C10H19N5O2Couleur et forme :NeatMasse moléculaire :241.29Ranolazine-d3
CAS :Produit contrôléFormule :C242H3H30N3O4Couleur et forme :NeatMasse moléculaire :430.56Avanafil
CAS :Produit contrôlé<p>Applications A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.<br>References Hatzimouratidis, K., et al.: Drugs, 68, 231 (2008);<br></p>Formule :C23H26ClN7O3Couleur et forme :WhiteMasse moléculaire :483.95(2-Amino-1H-benzimidazol-6-yl)(4-fluorophenyl)-methanone
CAS :Produit contrôlé<p>Applications The hydrolyzed form of Flubendazole (F418500), which is an anthelmintic.<br>References Thienpont, D., et al.: Arzneimittel-Forsch., 28, 605 (1978), Vanparijs, O., et al.: Vet. Parasitol, 5, 237 (1979),<br></p>Formule :C14H10FN3OCouleur et forme :Off-WhiteMasse moléculaire :255.25(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifl
CAS :Produit contrôlé<p>Applications Sitagliptin intermediate. A dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension.<br>References Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006)<br></p>Formule :C16H13F6N5OCouleur et forme :WhiteMasse moléculaire :405.305-Nitro-2-furaldehyde
CAS :Produit contrôlé<p>Applications 5-Nitro-2-furaldehyde is an intermediate in the synthesis of Nifurtimox (N458800), an antiprotozoal. Showing anti-Trypanosoma cruzi activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sastry, C.S.P., et. al.: Talanta, 41, 1957 (1994)<br></p>Formule :C5H3NO4Couleur et forme :NeatMasse moléculaire :141.08Dacarbazine-d6
CAS :Produit contrôlé<p>Applications Labelled Dacarbazine (D101400). Dacarbazine is used as an antineoplastic for treatment of malignant melanoma and sarcomas.<br>References Shealy, et al.: Biochem. Pharmacol., 11, 674 (1962), Carter, et al.: Eur. J. Cancer, 8, 85 (1972),<br></p>Formule :C62H6H4N6OCouleur et forme :Light Yellow SolidMasse moléculaire :188.2210α-Hydroxy Naloxone
CAS :Produit contrôlé<p>Impurity Naloxone EP Impurity C<br>Applications 10α-Hydroxy Naloxone is a hydroxylated analog of the opioid antagonist Naloxone (N285000(P)), which is a specific opioid antagonist; narcotic antagonist.<br>References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967), McNicholas, L.F., et al.: Drugs, 27, 81 (1984), Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985), Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)<br></p>Formule :C19H21NO5Couleur et forme :NeatMasse moléculaire :343.37Isoanastrozole
CAS :Produit contrôlé<p>Impurity Anastrozole EP Impurity G<br>Applications Isoanastrozole (Anastrozole EP Impurity G) is used in the preparation of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Zhu, Y., et. al.: Faming Zhuanli Shenqing, CN 103524439 A 20140122 (2014)<br></p>Formule :C17H19N5Couleur et forme :WhiteMasse moléculaire :293.371,2-Diisonicotinoylhydrazine
CAS :Produit contrôlé<p>Applications 1,2-Diisonicotinoylhydrazine is an iron chelator.<br>References Bernhardt, P.V., et. al.: J. Biol. Inorg. Chem., 10, 761 (2005)<br></p>Formule :C12H10N4O2Couleur et forme :NeatMasse moléculaire :242.23Nateglinide Ethyl Ester
CAS :Produit contrôlé<p>Applications The ethyl ester of the oral hypoglycemic agent Nateglinide (N379375). It showed no effects on gross behavior in mice.<br>References Maeda, K. et al.: Yak. Chir., 25, S157 (1997);<br></p>Formule :C21H31NO3Couleur et forme :NeatMasse moléculaire :345.48N-(2-Succinyl) Phenylephrine(Mixture of Diastereomers) ( >85%)
CAS :<p>Impurity N-(2-Succinyl) Phenylephrine Impurity<br>Applications The major degradation product identified in Acetaminophen, Phenylephrine hydrochloride, and Chlorpheniramine maleate.<br>References Wong, J., et al.: Anal. Chem., 78, 7891 (2006),<br></p>Formule :C13H17NO6Degré de pureté :>85%Couleur et forme :NeatMasse moléculaire :283.28Diazoxide-d3
CAS :Produit contrôlé<p>Applications Diazoxide-d3 is the labeled analogue of Diazoxide (D417305), which reduces status epilepticus neuron damage in diabetes.<br>References Baba, A., et al.: J. Neurosci., 23, 7737 (2003); Bancila, V., et al.: J. Neurochem., 90, 1243 (2004); Bancila, V., et al.: J. Biol. Chem., 280, 8793 (2005)<br></p>Formule :C8H4D3ClN2O2SCouleur et forme :NeatMasse moléculaire :233.694-Hydroxy Valsartan (Mixture of Diastereomers)
CAS :Produit contrôléFormule :C24H29N5O4Couleur et forme :NeatMasse moléculaire :451.52Ethyl p-Aminobenzoate-N-D-mannose
CAS :Produit contrôlé<p>Applications Ethyl p-Aminobenzoate-N-D-mannose is a derivative of Benzocaine (B202985) glucoside, a potential anaesthetic or potential screening agent.<br>References Rybczynska, B. et al.: Parfum. Kosm., 48, 125 (1967); Nikolin, A. et al.: Glas. Hemi. Tehnol. Bosne Herceg., 16, 93 (1968);<br></p>Formule :C15H21NO7Couleur et forme :NeatMasse moléculaire :327.335-Chloro-2-benzimidazolinone
CAS :Produit contrôléFormule :C7H5ClN2OCouleur et forme :GreyMasse moléculaire :168.58Chlorobenzene
CAS :Produit contrôlé<p>Applications Chlorobenzene is a halogenated benzene used in chemical toxicity QSAR research for agricultural pollution.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fielden, M., et al.: Curr. Opin. Drug Discovery Dev., 9, 84 (2006), Jonker, M., et al.: Carcinogenesis, 30, 1805 (2009), Jennen, D., et al.: Toxicol. Sci., 115, 66 (2010),<br></p>Formule :C6H5ClCouleur et forme :Clear ColourlessMasse moléculaire :112.56Lenalidomide
CAS :Produit contrôlé<p>Applications Lenalidomide is an immunomodulatory drug; analog of Thalidomide.<br>References Bartlett, J.B., et al.: Nature Rev., 4, 314 (2004), Mitsiades, C.S., et al.: Curr. Opin. Invest. Drugs, 5, 635 (2004), List, A., et al.: N. Engl. J. Med., 352, 549 (2005),<br></p>Formule :C13H13N3O3Couleur et forme :WhiteMasse moléculaire :259.26N,O-Dibenzoyl-DL-tyrosyl-N’,N’-dipropylamide
CAS :Produit contrôlé<p>Applications N,O-Dibenzoyl-DL-tyrosyl-N',N'-dipropylamide is a metabolite of the antispasmodic agent Tiropramide (T446900). Tiropramide impurity B.<br>References Janssen, et al.: J. Pharm. Pharmacol., 9, 381 (1956), Bertaccini, et al.: Br. J. Pharmac., 34, 310 (1968),<br></p>Formule :C29H32N2O4Couleur et forme :White To Light RedMasse moléculaire :472.58XL184
CAS :Produit contrôléFormule :C28H24FN3O5Couleur et forme :White To Off-WhiteMasse moléculaire :501.51N-[2-Chloro-3-(dimethylamino)-2-propen-1-ylidene]-N-methylmethanaminium Hexafluorophosphate
CAS :Formule :C7H14ClN2·F6PCouleur et forme :White To Light YellowMasse moléculaire :306.62Lacidipine
CAS :Produit contrôlé<p>Applications A dihydropyridine calcium channel blocker. Antihypertensive.<br>References Safar, M., et al.: Clin. Pharmacol. Ther., 46, 94 (1989), Kharat, V.R., et al.: J. Pharm. Biomed. Anal., 28, 789 (2002), McCormack, A.J., et al.: Drugs, 63, 2327 (2003),<br></p>Formule :C26H33NO6Couleur et forme :Light YellowMasse moléculaire :455.54Triallate
CAS :Produit contrôlé<p>Applications Triallate is a pesticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schneider, M., et al.: J. Environ. Qual., 42, 844 (2013); Busi, R., et al.: Pest Manag. Sci., 69, 1379 (2013)<br></p>Formule :C10H16Cl3NOSCouleur et forme :Light Brown To BrownMasse moléculaire :304.66N-Formyl Trimetazidine
CAS :<p>Stability Hygroscopic<br>Applications N-Formyl Trimetazidine is an impurity of Trimetazidine (T795610).<br>References Szwed, H., et al.: Clin. Drug Invest., 19, 1 (2000), Thoppil, S., et al.: J. Pharm. Biomed. Anal., 25, 15 (2001), Wang, Z., et al.: Pharmazie, 62, 27 (2007),<br></p>Formule :C15H22N2O4Couleur et forme :NeatMasse moléculaire :294.354’-(Bromomethyl)biphenyl-2-carboxylic Acid tert-Butyl Ester
CAS :Produit contrôlé<p>Impurity Telmisartan EP Impurity H<br>Applications 4’-(Bromomethyl)biphenyl-2-carboxylic Acid tert-Butyl Ester (Telmisartan EP Impurity H) is a biphenyl derivative used in the preparation of angiotensin II receptor antagonists. T017000<br>References Wahhab, A. et al.: Arzneim.-Forsch., 43, 1157 (1993); Yanagisawa, H. et al.: J. Med. Chem., 39, 323 (1996);<br></p>Formule :C18H19BrO2Couleur et forme :NeatMasse moléculaire :347.25Lansoprazole Sulfide N-Oxide
CAS :<p>Applications Used in the preparation of Lansoprazole and its metabolite and impurities.<br>References Reddy, G. et al.; Synthetic Commun. 38, 3477 (2008)<br></p>Formule :C16H14F3N3O2SCouleur et forme :Off White SolidMasse moléculaire :369.364-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone
CAS :Produit contrôlé<p>Impurity Rivaroxaban Impurity E<br>Applications 4-[4-[[(2R)-3-Chloro-2-hydroxypropyl]amino]phenyl]-3-morpholinone (Rivaroxaban Impurity E) is an impurity of Rivaroxaban (R538000), which is a antithrombotic agent and a FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formule :C13H17ClN2O3Couleur et forme :NeatMasse moléculaire :284.74Nateglinide
CAS :Produit contrôlé<p>Applications An amino-acid derivative that stimulates insulin secretion. Used as an antidiabetic.<br>References Shinkai, H., et al.: J. Med. Chem., 32, 1436 (1989), Sato, Y., et al.: Diabetes Res. Clin. Pract., 12, 53 (1991), Vicent, D., et al.: J. Clin. Invest., 111, 1373 (2003), Ceriello, A., et al.: Diabet. Med., 21, 171 (2004),<br></p>Formule :C19H27NO3Couleur et forme :White To Off-WhiteMasse moléculaire :317.421,2-Diphenyl Hydrazine
CAS :Produit contrôlé<p>Stability Air Sensitive (Oxidize)<br>Applications Impurity in the production of Phenylbutazone (P319570). Hydrazobenzene is a metabolic intermediate of Azobenzene.Carcinogenic.<br>References Chung, K., et al.: Mutation Res., 114, 269 (1983), Kawanishi, S., et al.: J. Biol. Chem., 261, 5952 (1986), Floyd, R., et al.: Carcinogenesis, 11, 1447 (1990), Shibutani, S., et al.: Nature, 349, 431 (1991),<br></p>Formule :C12H12N2Couleur et forme :OrangeMasse moléculaire :184.242-(4-Benzylpiperidin-1-yl)quinolin-8-ol
CAS :Degré de pureté :95.0%Masse moléculaire :318.42001342773443-Mercapto-2-methylpropanoic Acid
CAS :Produit contrôlé<p>Impurity Captopril EP Impurity C<br>Applications 3-Mercapto-2-methylpropanoic Acid (Captopril EP Impurity C) is a useful synthetic intermediate.<br>References Lewis, S.N. et al.: J. Het. Chem., 8, 571-580 (1971)<br></p>Formule :C4H8O2SCouleur et forme :NeatMasse moléculaire :120.17Desamino Chloroimiquimod
CAS :Produit contrôlé<p>Impurity Imiquimod USP Related Compound C<br>Applications Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.<br>References Megyeri, K., et al.: Mol. Cell Biol., 15, 2207, (1995), Witt, P.L., et al.: Cancer Res., 53, 5176 (1993), Edwards, L., et al.: Arch. Dermatol., 134, 25 (1998); Gerster, J. et al.: J. Med. Chem., 48, 3481 (2005);<br></p>Formule :C14H14ClN3Couleur et forme :NeatMasse moléculaire :259.73Atrazine
CAS :<p>Applications Selective herbicide. Potential symptoms of overexposure are irritation of eyes and skin; dermatitis, skin sensitization; dyspnea, weakness, incoordination, salivation; hypothermia; liver injury.This compound is a contaminant of emerging concern (CECs)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dalgaard-Mikkelsen, S., et al.: Pharmacol. Rev., 14, 225 (1962), Muller, K., et al.: J. Environ. Qual., 31, 309 (2002), Backhaus, T., et al.: Environ. Toxicol. Chem., 23, 258 (2004),<br></p>Formule :C8H14ClN5Couleur et forme :ColourlessMasse moléculaire :215.68Etiracetam Carboxylic Acid
CAS :<p>Impurity Levetiracetam EP Impurity A<br>Applications Etiracetam Carboxylic Acid (Levetiracetam EP Impurity A) is an Etiracetam (E932970) intermediate and a metabolite.<br></p>Formule :C8H13NO3Couleur et forme :White To Off-WhiteMasse moléculaire :171.192,6-Diamino-5-ethyl-5-phenyl-4(5H)-Pyrimidinone
CAS :Produit contrôléFormule :C12H14N4OCouleur et forme :NeatMasse moléculaire :230.27Efavirenz Pent-3-ene-1-yne (cis/trans Mixture)
Produit contrôlé<p>Applications Efavirenz Pen-3-ene-1-yne is an analog of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor and antiviral agent.<br>References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995)<br></p>Formule :C14H9ClF3NO2Couleur et forme :NeatMasse moléculaire :315.673-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline-d3
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of labelled Nilotinib.<br>References Zhang, G., et al.: Bioorg. Med. Chem. Lett., 19, 6691 (2009), Seeliger, M., et al.: Cancer Res., 69, 2384 (2009),<br></p>Formule :C11H7D3F3N3Couleur et forme :NeatMasse moléculaire :244.24Procymidox
CAS :Produit contrôlé<p>Applications Systemic agricultural fungicide.<br>References Ozer, N., et al.: J. Phytopathol., 158, 744 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),<br></p>Formule :C13H11Cl2NO2Couleur et forme :Off WhiteMasse moléculaire :284.145-Fluoro Risperidone
CAS :Produit contrôlé<p>Impurity Risperidone EP Impurity D<br>Applications 5-Fluoro Risperidone (Risperidone EP Impurity D) is a Risperidone (R525000) impurity.<br></p>Formule :C23H27FN4O2Couleur et forme :NeatMasse moléculaire :410.48Valsartan-d3
CAS :Produit contrôléFormule :C24H26D3N5O3Couleur et forme :Off-WhiteMasse moléculaire :438.5423-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol
CAS :Produit contrôlé<p>Impurity Metoprolol EP Impurity D<br>Applications 3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol (Metoprolol EP Impurity D) is a new byproduct detected in Metoprolol tartrate. Metoprolol (M338790) impurity.<br>References Erickson, M., et al.: J. Pharmac. Biomed. Anal., 13, 567 (1995),<br></p>Formule :C12H18O4Couleur et forme :WhiteMasse moléculaire :226.27Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid
CAS :Produit contrôlé<p>Applications Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid is a reactant used in the preparation of peptidase IV inhibitors.<br>References Park, W. et al.: Bioorg. Med. Chem. Lett., 21, 1366 (2011);<br></p>Formule :C15H18F3NO4Couleur et forme :NeatMasse moléculaire :333.3N-Nitrosomorpholine-d8
CAS :Produit contrôlé<p>Applications N-Nitrosomorpholine-d8 (CAS# 1219805-76-1) is a useful isotopically labeled research compound.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C42H8N2O2Couleur et forme :Light YellowMasse moléculaire :124.17Deshydroxyethoxy Ticagrelor
CAS :<p>Applications Deshydroxyethoxy Ticagrelor analog of Ticagrelor (T437700) an antiplatelet agent, and preventative in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases.<br>References Zhang, H. et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012);<br></p>Formule :C21H24F2N6O3SCouleur et forme :White To Off-WhiteMasse moléculaire :478.52Telmisartan-d4
CAS :Produit contrôlé<p>Applications Telmisartan-d4 is deuterium labelled Telmisartan (T017000). Telmisartan is an angiotensin II receptor antagonist.<br>References Wienen, W. et al.: Br. J. Pharmacol., 110, 245 (1993); Neutel, J.M. et al: Adv. Therap., 15, 206 (1998)<br></p>Formule :C33D4H26N4O2Couleur et forme :NeatMasse moléculaire :518.643-Hydroxy Medetomidine
CAS :Produit contrôlé<p>Applications A metabolite of Medetomidine (M203250).<br>References Salonen, J.S., et al.: Xenobiotica, 20, 471 (1990),<br></p>Formule :C13H16N2OCouleur et forme :NeatMasse moléculaire :216.28Methyl 5-chloro-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate
CAS :Produit contrôlé<p>Applications Methyl 5-chloro-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate (cas# 144172-24-7) is a useful research chemical. It is an intermediate in the synthesis of IN-KG 433 (I627995). IN-KG 433 is an impurity of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.<br>References Wang, H., et al.: Water. Sci. Technol., 61, 2733 (2010); Shono, T., et al.: Pesticide. Biochem. Physiol., 75, 1 (2003);<br></p>Formule :C11H9O4ClCouleur et forme :NeatMasse moléculaire :240.634’-(Trifluoromethyl)valerophenone-(E)-O-2-(2-aminoethyl) Oxime Maleate
Produit contrôlé<p>Applications 4’-(Trifluoromethyl)valerophenone(E)-O-2-(2-aminoethyl) Oxime Maleate is an impurity in the synthesis of Fluvoxamine (F603500), a selective serotonin reuptake inhibitor (SSRI) used as an anti-depressant. Antiobsessional.<br>References Claassen, V., et al.: Br. J. Pharmacol., 60, 505 (1977), Koran, L.M., et al.: J. Clin. Psychopharmacol., 16, 121 (1996), Ware, M.R., et al.: J. Clin. Psychiatry, 58, Suppl. 5, 15 (1997), Inazu, M., et al.: Neurochem. Int., 39, 39 (2001)<br></p>Formule :C20H28F3N3O5Couleur et forme :NeatMasse moléculaire :447.45Risperidone Z-Oxime Impurity
CAS :Produit contrôlé<p>Impurity Risperidone EP Impurity B<br>Applications Risperidone Z-Oxime (Risperidone EP Impurity B) is an impurity of Risperidone (R525000). Risperidone impurity per USP.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Formule :C23H28F2N4O2Couleur et forme :NeatMasse moléculaire :430.492-Chloro-10,11-dihydro-11-oxo-dibenzo[b,f][1,4]oxazepine
CAS :Produit contrôléFormule :C13H8ClNO2Couleur et forme :NeatMasse moléculaire :245.664-Nitrosopiperazine-1-ethanol
CAS :Formule :C6H13N3O2Couleur et forme :Light YellowMasse moléculaire :159.186Ofloxacin N-Oxide Acetic Acid Salt (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Applications A metabolite of Ofloxacin.<br>References Uematsu, T., et al.: Eur. J. Clin. Pharmacol., 40, 581 (1991), Uematsu, T., et al.: Ther. Drug Monit., 17, 101 (1995), Ballesteros, O., et al.: J. Pharm. Biomed. Anal., 30, 1103 (2002), Kitade, T., et al.: Chem. Pharm. Bull., 51, 53 (2003),<br></p>Formule :C18H20FN3O5·ClHCouleur et forme :NeatMasse moléculaire :437.419Firocoxib
CAS :<p>Applications A selective cyclooxygenase-2-(COX-2) inhibitor. Anti-inflammatory; analgesic.<br>References McCann, M.E., et al.: Am. J. Vet. Res., 65, 503 (2004),<br></p>Formule :C17H20O5SCouleur et forme :Off-WhiteMasse moléculaire :336.40Silodosin
CAS :<p>Applications Silodosin is an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertrophy.<br>References (1) Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995) (2) Murata, S., et al.: J. Urol., 164, 578 (2000)<br></p>Formule :C25H32F3N3O4Couleur et forme :NeatMasse moléculaire :495.532-Hydroxypyridine
CAS :Produit contrôlé<p>Applications 2-Hydroxypyridine (cas# 142-08-5) is a compound useful in organic synthesis.<br></p>Formule :C5H5NOCouleur et forme :White To Light BrownMasse moléculaire :95.10Propentofylline
CAS :Produit contrôléFormule :C15H22N4O3Couleur et forme :White To Off-WhiteMasse moléculaire :306.364-Desmethyl-2-methyl Celecoxib
CAS :Produit contrôlé<p>Applications 4-Desmethyl-2-methyl Celecoxib is an analog of Celecoxib (C251000). It is a cyclooxygenase 2 inhibitor.<br>References Penning, T., et al.: J. Med. Chem., 40, 1347 (1997); Wesolowski, S., et al.: Bioorg. Med. Chem. Lett., 12, 267 (2002)<br></p>Formule :C17H14F3N3O2SCouleur et forme :White To BeigeMasse moléculaire :381.37Nevirapine-d4 (cyclopropyl-2,2,3,3-d4)
CAS :Produit contrôlé<p>Applications Nevirapine-d4 (cyclopropyl-2,2,3,3-d4) (CAS# 1051418-95-1) is a useful isotopically labeled research compound. This can be prepared to use as non-nucleoside reverse transcriptase inhibitors.<br>References Gant, T., et.al., PCT Int.Appl., 113,(2008);<br></p>Formule :C15D4H10N4OCouleur et forme :NeatMasse moléculaire :270.33(1S,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
CAS :Produit contrôlé<p>Applications An intermediate in the synthesis of thephosphodiesterase 5 inhibitor Tadalafil (T004500).<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003),<br></p>Formule :C20H18N2O4Couleur et forme :White To YellowMasse moléculaire :350.37(R)-1-Boc-3-hydroxypiperidine
CAS :Produit contrôlé<p>Applications (R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. (R)-1-Boc-3-hydroxypiperidine has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kikuchi, T., et. al.: J. Labelled Comptd. Rad., 44, 31 (2001); Isakovic, L., et. al.: Bioorg. Med. Chem. Lett., 19, 2742 (2009)<br></p>Formule :C10H19NO3Couleur et forme :NeatMasse moléculaire :201.264-Chloromethyl-5-methyl-1,3-dioxol-2-one
CAS :Produit contrôlé<p>Applications 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an important reagent in the preparation of angiotensin II receptor antagonist such as Olmesratan Medoxomil (O550000). 4-Chloromethyl-5-methyl-1,3-dioxol-2-one is also used in the preparation of prodrugs of ampicillin.<br>References Ikeda, S. et al.: Chem. Pharmac. Bull., 32, 4316 (1984); Wu, T. Yaox. Xueb., 41, 537 (2006);<br></p>Formule :C5H5ClO3Couleur et forme :NeatMasse moléculaire :148.54Dibenzazepine-10,11-dione
CAS :Produit contrôlé<p>Applications Dibenzazepine-10,11-dione is an impurity of Oxcarbazepine (O869250). Dibenzazepine-10,11-dione is used as a reagent in the preparation of bifunctional dipolar electroluminescent template for optoelectronic applications.<br>References Chen, C.-T. et al.: Chem. Comm., 31, 3980 (2005); Heckendorn, R. et al.: Helv, Chim. Acta, 70, 1955 (1987);<br></p>Formule :C14H9NO2Couleur et forme :NeatMasse moléculaire :223.23Levosimendan Triazene Impurity
CAS :<p>Stability Light Sensitive<br>Applications Levosimendan Triazene is an impurity of Levosimendan (L378000); a positive inotropic agent with vasodilating activity. Also cardiotonic.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)<br></p>Formule :C22H23N7O2Couleur et forme :NeatMasse moléculaire :417.462-[3,5-Dichloro-4-(4-chlorobenzoyl)phenyl]-1,2,4-triazine-3,5(2H,4H)-dione
CAS :Produit contrôlé<p>Applications An anticoccidal triazine used for the treatment of coccidiosis in chickens. An impurity of Diclazuril (D436200).<br>References McFarland, J. et al.: J. Med. Chem., 35, 2543 (1992);<br></p>Formule :C16H8Cl3N3O3Couleur et forme :NeatMasse moléculaire :396.61Praziquantel
CAS :<p>Applications Anthelmintic, effective against flatworms.<br>References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),<br></p>Formule :C19H24N2O2Couleur et forme :White To Off-WhiteMasse moléculaire :312.41Olanzapine Pamoate Hydrate
CAS :Produit contrôlé<p>Applications A new Olanzapine pamoate formulation of a second-generation antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Davis, J., et al.: Arch. Gen. Psychiatry, 60, 553 (2003), Kahn, R., et al.: Lancet, 371, 1085 (2008), Lauriello, J., et al.: J. Clin. Psychiatry, 69, 790 (2008),<br></p>Formule :C23H16O6·C17H20N4S·H2OCouleur et forme :NeatMasse moléculaire :718.82(2-Piperidin-1-ylpyridin-4-yl)methylamine
CAS :Degré de pureté :97.0%Couleur et forme :SolidMasse moléculaire :191.2779998779297Hydrodolasetron
CAS :Produit contrôlé<p>Applications Hydrodolasetron, is the reduced form of Dolasetron (D528500), a specific serotonin (5HT3) receptor antagonist. Antiemetic.<br>References Boeijinga, P.H., et al.: Eur. J. Pharmacol., 219, 9 (1992), Miller, R.C., et al., Drug Dev. Res., 28, 87 (1993), Fauser, A.A., et al.: Eur. J. Cancer, 32, 1523 (1996), Graczyk, S.G., et al.: Anesth. Analg., 84, 325 (1997),<br></p>Formule :C19H22N2O3Couleur et forme :White To Off-WhiteMasse moléculaire :326.39
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