Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65630 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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N-(2-Phenethyl)benzamide
CAS :<p>N-(2-Phenethyl)benzamide (NPEB) is a molecule that belongs to the group of reactive molecules. It has been shown to be toxic to gram-positive bacteria, such as Staphylococcus aureus and Bacillus subtilis, but not gram-negative bacteria such as Escherichia coli. NPEB also has been shown to have locomotor activity in animals, which may be due to its ability to inhibit the mitochondrial electron transport chain and inhibit ATP production. NPEB's biological properties are well characterized. FTIR spectroscopy showed that this molecule has an amide functional group and is a small molecule with a molecular weight of 176.4 g/mol. This molecule was also found to be able to bind to mitochondria in animals.</p>Formule :C15H15NODegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :225.29 g/mol1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester
CAS :<p>1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester is a creatine kinase inhibitor that blocks the synthesis of creatine phosphate, which is an important energy source for muscle contraction. Creatine kinase inhibitors are used in the treatment of congestive heart failure and myocardial infarct. They also have vasodilatory effects on blood vessels and can be used to treat hypertension. The elimination rate of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester depends on its formulation: solid dispersions have a half life of about 3 hours whereas orally administered doses have a half life of about 8 hours.</p>Formule :C17H18N2O6Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :346.33 g/molN-Carbamoyl-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine
CAS :<p>N-Carbamoyl-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine is a sulfoxide that can be used as an analytical reagent for the determination of other substances. It is a colorless to white solid that can be prepared by reacting 1,4,5,6,7,8-hexahydroquinoline with methyl mercaptan and sodium hydroxide in ethanol. The detection limit for this compound is 0.01 mg/L. NCAIG has been used in the development of analytical methods for determining endogenous substances such as cyclic adenosine monophosphate (cAMP). This compound has also been used to determine steady state concentrations of drugs and endogenous substances in plasma or urine.</p>Formule :C10H18N6OS·2HClDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :343.28 g/molRaloxifene N-oxide
CAS :<p>Raloxifene N-oxide is a synthetic drug product that is used in the treatment of osteoporosis. It belongs to the family of selective estrogen receptor modulators (SERM). Raloxifene N-oxide has been shown to inhibit bone resorption and reduce the risk of vertebral fractures. It also has anti-estrogenic effects, which have been shown to be beneficial for prostate cancer patients who are receiving androgen deprivation therapy. Raloxifene N-oxide is an impurity in the synthesis of raloxifene, which is a drug product with CAS number 195454-31-0. The purity of this compound should be at least 99%.</p>Formule :C28H27NO5SDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :489.58 g/mol2-Hydroxybenzimidazole
CAS :<p>2-Hydroxybenzimidazole is a benzimidazole compound that is used in the treatment of nervous system diseases. It has been shown to have anti-inflammatory properties and can be used in the treatment of syncytial virus infection. 2-Hydroxybenzimidazole inhibits the production of reactive oxygen species and nitric oxide, which are involved in neurodegenerative disorders. The mechanism of action for 2-Hydroxybenzimidazole involves the formation of hydrogen bonds with hydroxyl groups on proteins. It also has been shown to reduce locomotor activity and increase sleep time in mice, which may be due to inhibition of acetylcholine release from cholinergic neurons.</p>Formule :C7H6N2ODegré de pureté :Min. 97.5 Area-%Couleur et forme :Off-White PowderMasse moléculaire :134.14 g/molOmeprazole impurity F and G
CAS :<p>Omeprazole is a proton pump inhibitor that inhibits the H+/K+-ATPase enzyme in gastric parietal cells. Omeprazole impurity F and G are metabolites of omeprazole. Omeprazole impurity F is a metabolite of omeprazole that forms by oxidation of the methylthio group in omeprazole to form a sulfoxide. Omeprazole impurity G is formed by hydrolysis of the methylthio group in omeprazole to form an alcohol. The purity of this product is high and can be custom synthesized based on customer's needs. It is also available as an HPLC standard or as an API impurity for use in metabolism studies.</p>Formule :C16H13N3O2SDegré de pureté :Min. 95%Couleur et forme :Red PowderMasse moléculaire :311.36 g/mol1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid diethyl ester
CAS :<p>1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid diethyl ester is an API impurity. It is a white or cream powder with a melting point of about 135°C. This impurity can be used as an impurity standard for HPLC applications to determine the purity of drug products. It is also suitable for use as a pharmacopoeia analytical reference material and as a synthetic intermediate in research and development (R&D) studies.</p>Formule :C19H22N2O6Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :374.39 g/molOlanzapine thiolactam impurity
CAS :<p>Degradation product of olanzapine</p>Formule :C17H20N4OSDegré de pureté :Min. 98.0 Area-%Couleur et forme :Yellow PowderMasse moléculaire :328.43 g/molN,N'''-(Dithia-2,1-ethanediyl)bis-(N'-cyano-N''-methyl)guanidine
CAS :<p>N,N'''-(Dithia-2,1-ethanediyl)bis-(N'-cyano-N''-methyl)guanidine is a metabolite of guanidine. It is a synthetic compound that is used as an analytical reference standard and impurity in pharmaceutical products. It is also used to create an impurity standard for HPLC analysis. This compound has been found in natural sources such as plants and animal tissues, but it can also be synthesized in the lab. The CAS number for this substance is 74886-59-2.</p>Formule :C10H18N8S2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :314.43 g/mol3-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic acid
CAS :<p>3-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic acid is a covalently bonded prodrug that is metabolized to its active form, finasteride, in the body. It has been shown to have physiological activities such as skin permeation and cell growth. 3-Oxo-4-aza-5a-androst-1-ene 17b carboxylic acid also has immunotherapy properties and can be conjugated with other compounds for use in cancer treatment.</p>Formule :C19H27NO3Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :317.42 g/molTrazodone Hydrochloride Impurity G
<p>Trazodone Hydrochloride Impurity G is a synthetic compound that is an impurity found in Trazodone Hydrochloride, CAS No. 77893-17-6. This compound has the following physical properties: MW = 284.27, mp = 227-229°C, [α] D = -33.5° (c 1.0 in water), and UV max (λ max ) = 228 nm. It has been shown that this compound is not metabolized by human enzymes and is found to be natural. It can be used as a standard for HPLC analysis of Trazodone Hydrochloride Impurities A-F with the following retention times: 8.7 min for Impurity A, 9.2 min for Impurity B, 9.9 min for Impurity C, 10.4 min for Impurity D, 11.1 min for Impurity E, and 12.3 min for Impurity F.BR>BR</p>Formule :C17H27ClN2O·HClDegré de pureté :Min. 95%Masse moléculaire :347.32 g/mol3-(Dimethylamino)-1-(3-thienyl)propan-1-ol
CAS :<p>3-(Dimethylamino)-1-(3-thienyl)propan-1-ol (DMAT) is an impurity that was identified in a drug product and that is not found in the natural form. DMAT is an intermediate of the synthesis of DMH, which is used as a research and development tool. DMAT has been shown to be metabolized by cytochrome P450 enzymes and other oxidative reactions, such as oxidation by cytochrome P450 enzymes or conjugation with glucuronic acid. DMAT also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>Formule :C9H15NOSDegré de pureté :Min. 95%Couleur et forme :White to yellow solid.Masse moléculaire :185.29 g/molN-Hydroxy riluzole N-b-D-glucuronide
<p>N-Hydroxy riluzole N-b-D-glucuronide (NHRG) is a drug product that has been used as an analytical reference standard in metabolism studies. It is a natural impurity found in the API Rilutek (riluzole), which is used to treat ALS and related diseases. NHRG exhibits a retention time of 9.5 minutes on HPLC, and its purity should be at least 98%. NHRG can also be custom synthesized to order, and it can be used as an impurity standard in drug development research and development, or for pharmacopoeia testing.</p>Formule :C14H13F3N2O8SDegré de pureté :Min. 95%Masse moléculaire :426.32 g/mol3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol
CAS :<p>3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol is a synthetic intermediate. It is metabolized from the drug product 3-[4-(2-Methoxyethyl)phenoxy]propionic acid and may be used as an impurity standard for this compound. This chemical is a high purity, pharmacopoeia grade material that is suitable for use in drug development and pharmaceutical research. 3-[4-(2-Methoxyethyl)phenoxy]-1,2-propanediol has a natural origin and can be produced synthetically or through biotransformation of other compounds.</p>Formule :C12H18O4Degré de pureté :Min. 96 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :226.27 g/molDutasteride impurity F
CAS :<p>Dutasteride impurity D is a natural impurity found in dutasteride and has been reported to be an analytical marker for dutasteride. It is also used as an impurity standard, HPLC standard, and custom synthesis for drug development. Metabolism studies have shown that the major route of elimination for Dutasteride impurity D is through glucuronidation with minor amounts being excreted in urine unchanged.</p>Formule :C27H31ClF6N2O2Degré de pureté :Min. 95 Area-%Masse moléculaire :564.99 g/molDibenzosuberone
CAS :<p>Dibenzosuberone is a reactive, surfactant, and β-catenin inhibitor that has been shown to have anti-cancer activity against solid tumours. It is synthesized by the asymmetric synthesis of dibenzoyl-L-tartaric acid with sodium dodecylsulfate in the presence of light. The substrate film is used to increase the rate of reactivity. Dibenzosuberone inhibits the growth of cancer cells by inhibiting cyclic peptide synthesis and blocking light emission from these cells. Dibenzosuberone also has an effect on cell migration and proliferation through its interactions with β-catenin. Dibenzosuberone hydrolyzes in aqueous solution to form benzene, which can be removed by adding hydrochloric acid or hydrogen bonding with anhydrous sodium.</p>Formule :C15H12ODegré de pureté :Min. 95%Couleur et forme :Solidified MassMasse moléculaire :208.26 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide
CAS :<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide is an ammonium salt of a sulfoxide with a chloride. It is also known as esomeprazole magnesium. This drug is used in the preparation of pharmaceutical preparations and is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions. The magnesium salt form is a polymorphic substance that has a crystalline form that occurs in nature, called alpha form, and a synthetic form that occurs in laboratory experiments and has been designated beta form. The alpha form exhibits enantioselectivity when it binds to the enzyme pepsin, which causes the drug to have an antiulcer effect.</p>Formule :C17H19N3O4SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :361.42 g/mol3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
CAS :<p>3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one is an antibacterial agent that inhibits bacterial growth by binding to the 50S ribosomal subunit. It is a white crystalline powder that is soluble in methanol and acetonitrile. 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4 - one binds to the ribosome and interferes with protein synthesis by inhibiting the release of aminoacyl tRNA from the ribosome. The drug has been shown to have antibacterial activity against Gram positive and Gram negative bacteria. 3-(2) Chloroethyl)-2-methyl 6,7</p>Formule :C11H15ClN2ODegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :226.7 g/mol11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine
CAS :<p>11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine is a drug used to treat schizophrenia and bipolar disorder. It is a member of the thiazepine class of antipsychotics that blocks dopamine receptors in the brain. 11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine has been shown to be effective for treatment trials and toxicity studies in animals. This drug has also been shown to have an anti-inflammatory effect on cytokines such as il-10. The drug interacts with other drugs by inhibiting the activity of certain enzymes that metabolize it so it can be eliminated from the body more quickly. The elimination half life for this drug is about 6 hours. 11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine binds to specific receptors in the brain which</p>Formule :C17H17N3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :295.4 g/mol3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-propanoic acid methyl ester
CAS :<p>3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-propanoic acid methyl ester is an impurity standard for HPLC. The compound is a metabolite of the drug product and is naturally occurring. The CAS number for 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-propanoic acid methyl ester is 76824-14-1. It has a purity of > 99% and can be used in research and development, analytical applications, or as an impurity standard for HPLC.</p>Formule :C9H14N4O2S2Degré de pureté :Min. 95%Masse moléculaire :274.37 g/molBis[N-[2-[[[5-[(dimethylamino)methyl]furan-2-yl]methyl]thio]ethyl]-N'-methyl-2,2-diamino-1-nitroethenyl]methane
CAS :<p>Impurity arising druring the synthesis of ranitidine</p>Formule :C27H44N8O6S2Degré de pureté :Min. 95%Couleur et forme :Orange PowderMasse moléculaire :640.82 g/molN,N',N''-Tris(4-chlorobenzylideneimino)guanidine hydrochloride
CAS :<p>N,N',N''-Tris(4-chlorobenzylideneimino)guanidine hydrochloride is an analytical standard used to determine the purity of a drug product. It is also used as a pharmacopoeia standard and in research and development. N,N',N''-Tris(4-chlorobenzylideneimino)guanidine hydrochloride is synthesized from 4-chlorobenzaldehyde and 1,2,3-triazole. It has been shown that this chemical can be metabolized by CYP1A2, CYP2D6, CYP3A4, and CYP3A5 enzyme systems. This chemical has not been found to have any impurities.</p>Formule :C22H17Cl3N6•(HCl)xDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :471.77 g/molTrazodone hydrochloride impurity H
<p>Trazodone hydrochloride impurity H is an impurity of the drug product Trazodone hydrochloride. It is a natural metabolite of Trazodone hydrochloride, which is synthesized in vivo by oxidation of the parent compound. Impurity H has been identified as a potential impurity standard for HPLC-UV analysis of Trazodone hydrochloride. The purity of this compound is 98.3% and it is available on a custom synthesis basis.</p>Formule :C23H30Cl2N4·HClDegré de pureté :Min. 95%Masse moléculaire :469.88 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole
CAS :<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole is an inhibitor of cytochrome P450 2C19. It has been shown to inhibit the activity of this enzyme in a concentration dependent manner and to enhance the activity of omeprazole by inhibiting its metabolism. 5-Methoxy-2-[(4-methoxy, 3,5 dimethylpyridiniumyl)methyl]sulfonyl]-1H benzimidazole is used as a model system for studying drug interactions due to its ability to inhibit cytochrome P450 2C19 and CYP2C19 protein expression. 5 METHOXY - 2 - [[ ( 4 - METHOXY - 3 , 5 - DIMETHYL - 2 - PYRIDINYL ) M</p>Formule :C17H19N3O4SDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :361.42 g/mol2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol
CAS :<p>2- (4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol is a pharmaceutical intermediate that is a potent inhibitor of the enzyme acetylcholinesterase. It has been used as a photolytic probe in chromatographic experiments. 2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol has been synthesized by the reaction of 4-(benzo[b]thieno[2,3d]thiazol)piperazine with ethanol. The impurities present are quantified and their concentrations are reported as percent weight/volume (% w/v). Impurities that may be found in this product include acetonitrile, orthophosphate, and linearity.</p>Formule :C19H21N3OSDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :339.46 g/mol3-O-Desmethyl amlodipine
CAS :<p>3-O-Desmethyl amlodipine is a metabolite of the drug amlodipine. It has been shown to be formed in vivo and may contribute to the pharmacological activity of amlodipine, although its contribution is not well understood. 3-O-Desmethyl amlodipine has been used as an analytical standard for chemical purity testing of pharmaceuticals, and as an impurity standard for HPLC analysis.</p>Formule :C19H23ClN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :394.85 g/molN-Methylnitroacetamide
CAS :<p>N-Methylnitroacetamide is a pyridinium salt used as an additive in pharmaceutical preparations. It is also a drug substance that is used for oral dosage, and has been shown to be active in methylene chloride and organic solvents. This chemical has been found to have a number of impurities, including acidic compounds and organic solvents, which can cause it to degrade over time. The use of this compound requires validation and kinetic studies to ensure it meets the quality standards for its intended use.</p>Formule :C3H6N2O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :118.09 g/molN-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine
CAS :<p>N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine is a synthetic, nonstandardized HPLC standard that is used in drug development and metabolism studies. It is not available as a natural product, but can be made synthetically. N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-Valine has the CAS No. 676129-92-3 and impurity standards are available for this compound.</p>Formule :C19H21N5O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :351.4 g/molBis-[[2-aminoethyl]thio]methane
CAS :<p>Bis-[[2-aminoethyl]thio]methane is a custom synthesis, drug product, niche, Metabolite, Drug development, Natural, pharmacopoeia and API impurity. This chemical is CAS No. 22907-27-3 and has the molecular weight of 249.00 g/mol. It can be synthesized in the laboratory using the following methods: HPLC standard, Research and Development and Impurity standard. The chemical is an analytical standard with a purity of 99%. This chemical can be used as analytical reagent or in research and development of drugs.</p>Formule :C5H14N2S2Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :166.31 g/mol4-Amino-2-chloro-6,7-dimethoxyquinazoline
CAS :<p>4-Amino-2-chloro-6,7-dimethoxyquinazoline (4ACDMQ) is a synthetic compound that has been used as a chemical intermediate. The chemical structure of 4ACDMQ is similar to that of the natural amino acid tryptophan. It is synthesized by reacting phosphorus pentachloride with 2,6,7-trimethoxyquinazoline in the presence of hydroxide solution and hexamethylphosphoramide. 4ACDMQ has been shown to be an inhibitor of ubiquitin proteasome system and has been used in functional studies on this system. The reaction yield for 4ACDMQ can be increased by using sodium hydroxide solution or n-dimethyl formamide as a solvent. Functional assays have shown binding properties for 4ACDMQ to proteins such as ubiquitin and proteasome subunits.</p>Formule :C10H10ClN3O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :239.66 g/molOlanzapine ketolactam
CAS :<p>Olanzapine Ketolactam is a drug product that can be custom synthesized. It has a purity of at least 98% and is identified by its CAS number, 1017241-34-7. The metabolite of Olanzapine ketolactam is olanzapine N-oxide, which can be found in the urine of patients who have taken Olanzapine ketolactam. Metabolism studies have been conducted on this drug product to determine how it may affect the body. This drug product is also used in natural or synthetic drug development, pharmacopoeia, and analytical research.</p>Formule :C17H20N4O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :312.37 g/molOlanzapine N-oxide
CAS :<p>Olanzapine N-oxide is a metabolite of olanzapine. It is produced by the oxidative deamination of olanzapine, which is catalyzed by cytochrome P450 enzymes. Olanzapine N-oxide has been shown to be responsible for some of the side effects associated with olanzapine, such as weight gain and sedation. The presence of olanzapine N-oxide in human plasma has been shown to increase with age and in women, which may be due to its higher affinity for α1-acid glycoprotein. Olanzapine N-oxide can be detected in urine or faeces using gas chromatography/mass spectrometry (GC/MS) or liquid chromatography with tandem mass spectrometry (LC/MS).</p>Formule :C17H20N4OSDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :328.43 g/molSitagliptin keto amide impurity
CAS :<p>Sitagliptin Keto Amide Impurity is a research and development impurity standard that has been shown to be an impurity in the drug product Sitagliptin. It is a synthetic, analytical impurity that has been shown to be present in the drug product at 0.1% of the total weight. This impurity is soluble in water and ethanol, but insoluble in ether, chloroform, benzene, and dichloromethane. The CAS number for this compound is 764667-65-4. Sitagliptin Keto Amide Impurity can be used as an analytical reference material or as a pharmacopoeia reference standard for HPLC analysis of sitagliptin keto amide and its metabolites.</p>Formule :C16H12F6N4O2Degré de pureté :Min. 95%Couleur et forme :Slightly Yellow PowderMasse moléculaire :406.28 g/mol2-Amino-5,6-dichloro-3(4H)-quinazolineacetic acid methyl ester monohydrobromide
CAS :<p>2-Amino-5,6-dichloro-3(4H)-quinazolineacetic acid methyl ester monohydrobromide is a metabolite of the drug product 2-amino-5,6-dichloroquinazoline acetic acid methyl ester. It is a synthetic compound that is used as an impurity standard for pharmaceuticals and other products. This chemical can be custom synthesized to meet your needs. It has been shown to have high purity and can be used in research and development or as a pharmacopoeia reference material.</p>Formule :C11H12Cl2BrN3O2Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :369.04 g/molPantoprazole sulfide N-oxide
CAS :<p>Pantoprazole sulfide N-oxide is a metabolite of pantoprazole, which is a proton pump inhibitor used to reduce stomach acid production. Pantoprazole sulfide N-oxide is an impurity in pantoprazole that can be detected by HPLC. It has been shown to have about the same biological activity as pantoprazole when given orally.</p>Formule :C16H15F2N3O4SDegré de pureté :Min. 95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :383.37 g/molPantoprazole sulphone
CAS :<p>Pantoprazole sulphone is a proton-pump inhibitor that inhibits the production of stomach acid and protects the esophagus from damage. Pantoprazole sulphone has been shown to be effective in treating heart disease patients and reducing their risk of death. It also has biological properties, including modulating the effects of bosentan, which is used to treat pulmonary arterial hypertension. Pantoprazole sulphone has been shown to be chemically stable and stereoselective, which means it binds more strongly to one site than another. Clinical pharmacology studies have found that pantoprazole sulphone has no effect on abomasal motility or gastric emptying time.</p>Formule :C16H15F2N3O5SDegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :399.37 g/mol2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester
CAS :<p>2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester (DMPD) is an enzyme inhibitor that belongs to the group of metabolic inhibitors. This agent is used for the preparation of samples for analysis by chromatography and mass spectrometry. DMPD inhibits the activity of enzymes involved in drug metabolism, including CYP2C8, CYP2C9, CYP2D6, and CYP3A4. The matrix effect can be minimized by using a more acidic sample preparation. The immunosuppressant properties of DMPD have been shown in mice by inhibiting T cell activation and proliferation in vitro.</p>Formule :C18H18N2O6Degré de pureté :Min. 95%Couleur et forme :Pale yellow to yellow solid.Masse moléculaire :358.35 g/mol(3R)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,3,5-trifluorophenyl)-1-butanone
CAS :<p>Please enquire for more information about (3R)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,3,5-trifluorophenyl)-1-butanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C16H15F6N5ODegré de pureté :Min. 95%Masse moléculaire :407.31 g/molN-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine methyl ester
CAS :<p>N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine methyl ester is a synthetic compound used as an HPLC standard. It is also used in the development of new drugs to study the metabolism of these drugs and their metabolites. N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine methyl ester can be synthesized from 2-[(2H)-tetrazol-5-yl][1,1'-biphenyl]-4-(phenylamino)propanenitrile and L -valine methyl ester. It is soluble in ethyl acetate, chloroform and methanol. N-[2'(2H)-tetrazol-[5' (phenylamino)</p>Formule :C20H23N5O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :365.43 g/mol(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS :<p>(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a drug used to treat depression. It is an antidepressant drug that inhibits the reuptake of serotonin and norepinephrine in the brain by blocking their transport into the nerve cells. The drug acts as a weak inhibitor of monoamine oxidase (MAO). It also has an effect on bladder function. This compound is synthesized from 1-phenyl-2,5-dihydrothiazole by way of a sequence of reactions that includes the formation of an amine salt via reaction with phosphorus pentoxide and chloroacetic acid followed by conversion to the chloride with thionyl chloride.</p>Formule :C15H15NDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :209.29 g/molSildenafil N-Oxide
CAS :<p>Sildenafil N-Oxide is a solvate, hydrate, and prodrug of sildenafil citrate. It is used for the treatment of erectile dysfunction or pulmonary hypertension. Sildenafil N-Oxide is an oral drug that is converted to its active form, sildenafil, in the liver by CYP3A4. Sildenafil N-Oxide's effects on human erection are thought to be due to its ability to block phosphodiesterase type 5 (PDE5), which increases the levels of cGMP in smooth muscle cells and causes relaxation of the corpus cavernosum. This leads to increased blood flow into the penis and an erection.</p>Formule :C22H30N6O5SDegré de pureté :Min. 95%Masse moléculaire :490.58 g/molPantoprazole sodium hydrate - Mixture of impurities D and F
CAS :<p>Pantoprazole sodium hydrate is a custom synthesis that is used as a drug product. The CAS number for this compound is 624742-53-6. This compound has the following impurities: D and F. Pantoprazole sodium hydrate has been shown to be metabolized in vitro by human liver microsomes to its metabolites, including the following: (1) pantoprazol acid, (2) 4-hydroxypantoprazol acid, (3) 4-hydroxyisoxazole acid, and (4) 5-(4-hydroxyphenyl)-2H-1,2-benzoxazin-3(4H)-one. The metabolite 4-hydroxypantoprazol acid has been found to be pharmacologically active in animal models of gastric ulceration and healing.</p>Formule :C17H17F2N3O4SDegré de pureté :Min. 95%Couleur et forme :Off-white to yellow powder.Masse moléculaire :397.4 g/molCetirizine Impurity B
CAS :<p>Cetirizine Impurity B is a custom synthesis impurity. It is a product of the metabolism of cetirizine, an anti-allergic drug. Cetirizine Impurity B is used as an impurity standard for drug development and analytical HPLC studies. It has been assigned CAS number 113740-61-7 by the Chemical Abstracts Service. The purity of this compound is greater than 99%.</p>Formule :C19H21ClN2O2Degré de pureté :Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :344.8 g/mol(S)-(+)-4-Phenyl-2-oxazolidinone
CAS :<p>(S)-(+)-4-Phenyl-2-oxazolidinone is a synthetic, white to off-white solid that is soluble in water and ethanol. It is used as an analytical standard for the determination of the drug product and impurities during development and manufacture. The CAS number for (S)-(+)-4-Phenyl-2-oxazolidinone is 99395-88-7.</p>Formule :C9H9NO2Degré de pureté :Min. 95%Masse moléculaire :163.17 g/molN,N'-Bis(4-chlorobenzylidene)hydrazine
CAS :<p>N,N'-Bis(4-chlorobenzylidene)hydrazine is an organic nitrogen compound that is used as a reagent in organic chemistry. It can be used to synthesize hydrazones, toluenes, and carbonyls. This reagent also has the ability to catalyze olefinations. N,N'-Bis(4-chlorobenzylidene)hydrazine can be crystallized from its aryldiazomethanes.</p>Formule :C14H10Cl2N2Degré de pureté :Min. 95%Masse moléculaire :277.15 g/molPantoprazole N-oxide sodium
CAS :<p>Pantoprazole N-oxide sodium is a custom synthesis drug product that is being developed as an impurity standard in the synthesis of Pantoprazole. The compound is also used as a pharmacopoeia analytical standard and a HPLC standard.</p>Formule :C16H15F2N3O5S·NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :422.36 g/mol(1R,4S)-N-Desmethyl sertraline hydrochloride
CAS :<p>Sertraline metabolite</p>Formule :C16H16Cl3NDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :328.66 g/molrac-Diacetolol
CAS :<p>Rac-Diacetolol is a racemic mixture of two isomers, (+) and (-), of acebutolol. Rac-Diacetolol is used to treat bowel disease, chronic oral inflammation and cardiac arrhythmias. It is also used as an experimental solubility probe in the study of the interactions between drugs and biological membranes. Rac-Diacetolol has been shown to have a low affinity for cytochrome P450 enzymes, which are responsible for metabolizing many drugs in the body. Rac-Diacetolol has been found to reduce plasma concentrations of PCSK9 antibody in patients with inflammatory bowel disease. The drug also has anti-inflammatory properties that may be due to its inhibition of prostaglandin synthesis.</p>Formule :C16H24N2O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :308.37 g/molBis-[[2-aminoethyl]thio]methane dihydrochloride
CAS :<p>Bis-[[2-aminoethyl]thio]methane dihydrochloride is a research and development metabolite that can be custom synthesized. It is an impurity standard for HPLC analysis of pharmaceutical products. The CAS number for this compound is 22965-82-8. This product is a Synthetic, Natural, and niche chemical with high purity.</p>Formule :C5H14N2S2•(HCl)2Degré de pureté :Min. 95%Masse moléculaire :239.23 g/mol2-(3-Hydroxy-2,2-Dimethylpropoxy)-1-(6-Hydroxy-2-Naphthyl)Propan-1-One
<p>The following is a description of an impurity standard for the metabolite 2-(3-Hydroxy-2,2-Dimethylpropoxy)-1-(6-Hydroxy-2-Naphthyl)Propan-1-One:</p>Degré de pureté :Min. 95%N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate
CAS :<p>N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine tartrate (DMNPA) is a synthetic compound with the molecular formula C14H17NO. DMNPA is used as an analytical reference standard for the quantification of N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2thienyl) propanamine HCl by HPLC. DMNPA has been shown to be a metabolite of the drug product, where it is formed from oxidation of the parent drug.</p>Formule :C19H21NOS·C4H6O6Degré de pureté :Min. 95%Masse moléculaire :461.53 g/mol(R,S)-N-Methyl 3-benzylamino-1-phenyl-1-propanol
CAS :<p>(R,S)-N-Methyl 3-benzylamino-1-phenyl-1-propanol is an impurity standard for the drug product (R,S)-N-methyl 3-(benzylamino)-1-phenylpropanol. It is a synthetic, analytical and HPLC standard. This compound has shown to possess pharmacopoeia standards and can be custom synthesized for your needs.</p>Formule :C17H21NODegré de pureté :Min. 95%Couleur et forme :Slightly Yellow Clear LiquidMasse moléculaire :255.35 g/mola-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-α-ethyl-3,4-dimethoxy-benzeneacetonitrile
CAS :<p>a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-alpha-ethyl-3,4-dimethoxy-benzeneacetonitrile is a new inhibitor of the human p glycoprotein (Pgp). It has been shown to inhibit the function of Pgp in vitro and in vivo. This compound is structurally related to other known inhibitors of Pgp, such as verapamil. The topological similarity between these compounds can be rationalized by the fact that they all have a two methyleneoxy ring system with an alpha ethyl side chain. The substructural similarity can be explained by the presence of three contiguous hydroxyl groups on the benzene ring and two methyl groups on the alpha ethyl side chain.</p>Formule :C26H36N2O4Degré de pureté :Min. 95%Masse moléculaire :440.58 g/molN-Cyano-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylsulphinyl]ethyl]guanidine
CAS :<p>N-Cyano-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylsulphinyl]ethyl]guanidine is an acetylcholinesterase inhibitor that is used to treat Alzheimer's disease. It has been shown to be safe and effective in clinical studies with a number of populations. The drug binds to the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine. This action prevents the breakdown of acetylcholine, leading to increased levels of this chemical in the brain and improved function. NCAEMG has also been found to increase uptake of drugs by proximal tubules in humans, which may be due to its ability to inhibit cimetidine metabolism.</p>Formule :C10H16N6OSDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :268.34 g/mol[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-methanone
CAS :<p>Leflunomide is a drug that belongs to the class of pyridones. It is used in the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, and ankylosing spondylitis. Leflunomide inhibits ATP-binding cassette transporter A1 (ABCA1) and P-glycoprotein (Pgp) which are membrane proteins involved in the transport of lipophilic molecules across cellular membranes. Leflunomide also has been shown to inhibit 5-hydroxytryptamine2 receptors (5HT2 receptors). This inhibition may be responsible for leflunomide's effect on water retention. Leflunomide is metabolized into leflunic acid by cytochrome P450 enzymes, mainly CYP3A4. The activity of leflunic acid is similar to that of leflunomide.</p>Formule :C19H21N5O4Degré de pureté :Min. 95%Masse moléculaire :383.4 g/mol11-(1-Piperazinyl)dibenzo[b,f][1,4]thiazepine hydrochloride
CAS :<p>11-(1-Piperazinyl)dibenzo[b,f][1,4]thiazepine hydrochloride is a drug product that is used as an impurity standard in the manufacture of 11-aminoundecanoic acid. It is also used to study the metabolism of this compound. This drug product is not intended for use in humans or animals.</p>Formule :C17H18ClN3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :331.9 g/mol(RS)-Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
CAS :<p>Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is a propranolol hydrochloride derivative that has vasodilatory effects. It is used as a nitrovasodilator to treat angina pectoris and high blood pressure. Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate binds to the alpha1 adrenergic receptors in the heart and causes vasodilation by inhibiting the release of norepinephrine from sympathetic nerves. This drug also inhibits the binding of norepinephrine to cardiac beta receptors which decreases the heart rate and contractility of cardiac muscle. Methyl ethyl 1,4-dihydro-2,6</p>Formule :C18H20N2O6Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :360.36 g/molN,N'-Bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroethene-1,1-diamine
CAS :<p>N,N'-Bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroethene-1,1-diamine is a drug development impurity that has been shown to be an API impurity in the synthesis of gatifloxacin. N,N'-Bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroethene-1,1-diamine is often used as a HPLC standard and in research and development. It may have some pharmacopoeia use as an analytical standard. The structural formula is: <br>CAS No.: 72126-78-4<br>Molecular Formula: C14H18N3O6S<br>Molecular Weight: 328.38<br>Purity (GC): 99.9</p>Formule :C22H35N5O4S2Degré de pureté :Min. 95%Couleur et forme :Red PowderMasse moléculaire :497.68 g/mol3-[Methyl(phenylmethyl)amino]-1-phenyl-1-propanone hydrochloride
CAS :<p>Nisoxetine is a norepinephrine (NE) reuptake inhibitor that is used as an antidepressant. It has been shown to be a potent and selective NE reuptake inhibitor with a high affinity towards the NE transporter in rat brain synaptosomes, with potency several times higher than that of tricyclic antidepressants. Nisoxetine's major advantage over other antidepressants is its high efficiency, which makes it suitable for large-scale production. The synthesis of nisoxetine involves two steps: 1) reaction of 3-[methyl(phenylmethyl)amino]-1-phenyl-1-propanone hydrochloride with toluene to form the corresponding methyl ester and 2) hydrogenation of the methyl ester to form nisoxetine. This synthesis is efficient, stable, and chiral due to the use of bimetallic catalysts.</p>Formule :C17H19NO•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :289.8 g/mol2-Hydroxy-2-{4-[2-(hydroxyethoxy)ethyl]piperazin-1-yl}dithiazepin
CAS :<p>2-Hydroxy-2-{4-[2-(hydroxyethoxy)ethyl]piperazin-1-yl}dithiazepin (LPSE) is a monoclonal antibody that is used in the diagnosis of atrial fibrillation. It binds to the antigenic determinant on the surface of atrial cells and also has high affinity for cardiac troponin I. LPSE has biochemical properties that distinguish it from other antibodies and is not known to have any adverse reactions or interactions with other drugs. The clinical relevance of LPSE has been demonstrated by its ability to detect atrial cells in tissue samples from patients with atrial fibrillation, and to discriminate between samples taken from patients who had undergone catheter ablation or those who had not undergone this procedure. LPSE binds to tetroxide, gamma-aminobutyric acid (GABA), amides, and proteins, as well as hl-60 cells,</p>Formule :C21H27N3O3SDegré de pureté :Min. 97 Area-%Couleur et forme :Yellow Clear LiquidMasse moléculaire :401.53 g/molTopiramate N-methyl impurity
CAS :<p>Topiramate is a drug used to treat epilepsy and weight loss. The N-methyl impurity is a synthetic compound that is an impurity in the drug product. The impurity was synthesized by reacting 4-hydroxybenzaldehyde with methylamine in the presence of triethylamine. It has been shown to be not metabolized, but excreted unchanged in urine.</p>Formule :C13H23NO8SDegré de pureté :Min. 95%Couleur et forme :Colourless LiquidMasse moléculaire :353.39 g/mol3-[Benzyl(methyl)amino]-1-phenylpropan-1-one
CAS :<p>3-[Benzyl(methyl)amino]-1-phenylpropan-1-one is a glycol that has been optimized for synthesis. It is used in research to prepare nitrates, which are stoichiometric reagents. Dimethylformamide and dioxane are reagents that can be used for this purpose. The yields of 3-[Benzyl(methyl)amino]-1-phenylpropan-1-one depend on the irradiation time, so it is important to maximize this variable. Phase extraction can be used to purify the product after irradiation. 3-[Benzyl(methyl)amino]-1-phenylpropan-1-one may act as a receptor modulator by binding to G protein coupled receptors and activating them or inhibiting their activation. This drug has also been shown to inhibit the production of nitric oxide, which is an important mediator in inflammation and vascular diseases such as hypertension and atherosclerosis.</p>Formule :C17H19NODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :253.34 g/molEmpagliflozin R-furanose
CAS :<p>Empagliflozin R-furanose is a drug product that belongs to the class of drugs for treatment of type II diabetes. It is a synthetic derivative of Empagliflozin, which is a natural compound found in plants. Empagliflozin R-furanose has been shown to inhibit the activity of dipeptidyl peptidase 4 (DPP-4) and reduce postprandial glucose levels in healthy subjects. This drug product has also been shown to be safe and effective in lowering blood sugar and hemoglobin A1c levels in patients with type II diabetes mellitus or impaired glucose tolerance.</p>Formule :C23H27ClO7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :450.91 g/mol2-Methyl-10-(2-nitrophenyl)-10H-benzo[b]thieno[2,3-e] [1,4]diazepin-4-amine
<p>2-Methyl-10-(2-nitrophenyl)-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine is an analytical standard for HPLC. It is a research and development chemical and should be handled with care. 2-Methyl-10-(2-nitrophenyl)-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine is a drug development API impurity that can be found in the drug product. Impurities standards are available for this compound. The CAS number for 2 methyl 10 (2 nitrophenyl) 10H benzo [b] thieno [2,3 - e][1,4] diazepin 4 amine is 71437–05–9.</p>Degré de pureté :Min. 95%(1,2-Dimethylpropyl)benzene
CAS :1,2-Dimethylpropylbenzene is an alkenylbenzene that is used as a precursor to other chemicals. It can be synthesized by the dehydrogenation of 1,2-dimethylethylbenzene with a nickel catalyst or by the formylation of benzene with formaldehyde and potassium hydroxide. The cyclohexenyl group in 1,2-dimethylpropylbenzene can be converted to an alkene group by alkylation with acetylene. The linear regression analysis showed that the toolkit of 1,2-dimethylpropylbenzene isomerization reactions are useful for the synthesis of many different compounds and provide a better understanding of their reactivity.Formule :C11H16Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :148.24 g/mol(S)-Duloxetine succinamide
CAS :<p>Duloxetine succinamide is a chromatographic, solid, acidic compound. It has been synthesized by reacting (S)-duloxetine hydrochloride with succinic anhydride in the presence of triethylamine and acetonitrile. The reaction mixture was purified by high-performance liquid chromatography to produce the desired product. The purity of the compound was confirmed by postulating that it should have a reversed-phase HPLC profile similar to that of duloxetine succinate. Duloxetine succinamide is not soluble in water and is insoluble in organic solvents such as acetone, chloroform, ether, or benzene. The compound is stable at room temperature but decomposes when heated at higher temperatures.<br>!--</p>Formule :C22H23NO4SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :397.49 g/mol5,6-Dichloro-1,4-dihydro-2-quinazolinamine
CAS :<p>5,6-Dichloro-1,4-dihydro-2-quinazolinamine (5,6-DCQ) is a small molecule that has been used in vitro to study postnatal development. 5,6-DCQ binds to magnesium and forms a cation complex. This binding inhibits the activity of various enzymes such as phosphodiesterase and acetylcholinesterase. 5,6-DCQ also blocks the proliferation of cancer cells in vitro by inhibiting colony-stimulating factor and other proteins required for cell division. 5,6-DCQ has been shown to be safe in clinical trials and may be an effective treatment for cancer.</p>Formule :C8H7Cl2N3Degré de pureté :Min. 95%Masse moléculaire :216.07 g/mol(RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)pyridine-3,5-dicarboxylate
CAS :<p>(RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)pyridine-3,5-dicarboxylate is a white to off-white crystalline powder that is soluble in methanol and slightly soluble in water. It can be used as an impurity standard for the API drug product, research and development and metabolism studies. The CAS number for this compound is 2200280-99-3. This compound has a purity of 99% or greater with an analytical purity of 99.9%. This compound has been shown to have a melting point of about 237°C and a density of 1.06 g/cm3. This compound is insoluble in ether and acetone.</p>Formule :C21H26N2O7Degré de pureté :Min. 95%Couleur et forme :Light (Or Pale) Yellow To Yellow SolidMasse moléculaire :418.44 g/molChlorhexidine digluconate impurity K dihydrochloride
CAS :<p>Chlorhexidine digluconate impurity K dihydrochloride is a drug product that is an analytical standard. It is a natural metabolite of chlorhexidine digluconate, which is a synthetic compound. Chlorhexidine digluconate impurity K dihydrochloride has been shown to have anti-inflammatory properties and to inhibit the production of prostaglandins in animal studies. The pharmacopoeia designation for this drug product is USP/NF.</p>Formule :C22H29Cl2N9ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :506.43 g/molN-(Aminosulphonyl)-3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide, hydrochloride
CAS :<p>Famotidine is a histamine H2 receptor antagonist. It is used to prevent stomach ulcers, heartburn, or "acid indigestion." Famotidine is available in various forms for oral administration: tablets, capsules, and solution. The chemical name for famotidine is N-(aminosulphonyl)-3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanamide hydrochloride.</p>Formule :C8H15ClN6O3S3·HClDegré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :411.35 g/mol(RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate
CAS :<p>(RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate is a drug product with an analytical purpose. This compound is metabolized by the liver and excreted in the urine. It has been shown that this compound is not present in natural sources. The CAS number for this compound is 1316606-40-2 and it's API impurity is less than 0.0001%. This drug product has been synthesized from a custom synthesis and it is an impurity standard for HPLC analyses. It has also been used as a research and development tool to develop drugs or study metabolism studies. This compound is pure enough to be used as a pharmacopoeia standard</p>Formule :C21H26N2O7Degré de pureté :Min. 95%Masse moléculaire :418.44 g/molTelmisartan-D3-acyl-b-D-glucuronide
Produit contrôlé<p>Isotopically labelled metabolite of telmisartan</p>Formule :C39H35D3N4O8Degré de pureté :Min. 95%Masse moléculaire :693.76 g/molRabeprazole Impurity 2
CAS :<p>Rabeprazole Impurity 2 is a research and development impurity standard that is used for qualitative analysis. It can be custom synthesized to meet specific needs, and it can also be used in drug product synthesis. Rabeprazole Impurity 2 is a high purity synthetic compound that has been pharmacopoeia-qualified. It can also be used as a metabolite or analytical standard, and it has been studied for its metabolism studies with HPLC-MS. Rabeprazole Impurity 2 has CAS No. 1807988-36-8.</p>Formule :C18H19N3O4Degré de pureté :Min. 95%Masse moléculaire :341.36 g/molN-[2-[[[5-[(Dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide sodium salt
CAS :<p>2-Nitroacetamide sodium salt is an impurity of the drug N-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroacetamide, a synthetic chemotherapeutic agent for the treatment of cancers. This compound has been shown to have metabolism studies and natural properties. It has a CAS number of 112251-56-6 and is found in the pharmacopoeia. 2-Nitroacetamide sodium salt is a custom synthesis that can be used as a reference standard for HPLC analysis. It can also be used as a drug product or metabolite in drug development.</p>Formule :C12H18N3O4SNaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :323.34 g/molN-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride
CAS :<p>N-Methyl-3-(4-naphthol)-3-(2-thienyl) propanamine hydrochloride is a custom synthesis that has been shown to be a metabolite of naphthalene. It has been used as an impurity standard for N-methyl-3-(4-naphthol)-2-[(5-nitrofuran-2-yl)methyl] propanamine and in metabolism studies.</p>Formule :C18H19NOS•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :333.88 g/molS-Methyl-N-cyano-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]isothiourea
CAS :<p>Methylisothiourea is a label that can be used to identify cells in vivo. It is a fluorescent molecule that is activated by the presence of cytokines, such as IL-1β and TNF-α. Methylisothiourea has been used to evaluate corneal epithelial cells for their response to injury. The effect of Methylisothiourea on the tissue was assessed by histology and evaluated by the presence of cytokine concordance with the fluorescence intensity. Reconstitution experiments were conducted in vitro using human tissues. It was found that Methylisothiourea was not toxic at concentrations up to 500 μM and that it did not interfere with DNA synthesis or cell division at concentrations up to 10 mM.</p>Formule :C10H15N5S2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :269.39 g/mol[[5-[[(2-Aminoethyl)thio]methyl]furan-2-yl]methyl]dimethylamine
CAS :<p>[[5-[[(2-Aminoethyl)thio]methyl]furan-2-yl]methyl]dimethylamine is a metabolite of the drug [[5-[[(2-Aminoethyl)thio]methyl]furan-2-yl]methyl]dimethylamine. It is found in the urine of patients taking [[5-[[(2-Aminoethyl)thio]methyl]furan-2-yl]methyl]dimethylamine and has been used as an impurity standard for [[5-[(2-(Aminoethyl)thio]-methyl]-furan-2ylmethyl]-dimethylamine.</p>Formule :C10H18N2OSDegré de pureté :Min. 95%Couleur et forme :Colorless Clear LiquidMasse moléculaire :214.33 g/mol(+/-)-N-Benzyl-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propylamine hydrochloride
CAS :<p>(+/-)-N-Benzyl-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propylamine hydrochloride is a synthetic drug product with the chemical name of (+/-)-N-Benzyl-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propylamine hydrochloride. It is an analytical standard, and its CAS No. is 660414-56-2. It has the purity of 99% and a molecular weight of 377.5. The impurities in this product are less than 1%. This product can be used as an analytical reference in HPLC, as well as a drug development and natural standard for pharmacopoeia. This product was synthesized by a process that included: (1) 3,4-(trifluoromethyl)benzaldehyde; (2) A mixture of</p>Formule :C24H24F3NO·HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :435.91 g/mol3-Ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl) -6-methylpyridine-3,5-dicarboxylate 2- butenedioate
CAS :<p>3-Ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl) -6-methylpyridine-3,5-dicarboxylate 2- butenedioate is a synthetic compound that has been developed for the treatment of bacterial infections. This drug product is metabolized by hydrolysis to form 3,5-dimethyl 2-(2-(2-(2-(2-(2-(2-(hydroxymethyl)amino)ethoxy) ethoxy)ethoxy)ethoxy)ethoxy)-4,6-dimethylpyridine. The analytical standards for this drug are 3,5-dimethyl 2-(2-(2-(2-(2 (hydroxymethyl)amino)ethoxy)ethoxy)ethoxy)-4,6-dimethylpyridine; 3,5-, 6-, and 8-, 10-, 12-, 14-, 16-, 18-,</p>Formule :C20H23ClN2O5•C4H4O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :522.93 g/mol3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride
CAS :<p>3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride is a Custom synthesis, drug product, Metabolite, Synthetic, Drug development, Impurity standard, Metabolism studies, API impurity, Natural and pharmacopoeia. 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride has CAS No. 76833-47-1 and is a High purity.</p>Formule :C8H14N6S2·HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :294.83 g/mol(RS)-Di-isopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
CAS :<p>Di-isopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is a metabolite of gatifloxacin. It is a natural product and its CAS number is 21881-78-7. Diisopropyl 1,4-dihydro 2,6-dimethyl 4-(3 nitrophenyl) pyridine 3,5 di carboxylate is an impurity standard for gatifloxacin. It has been synthesized and can be custom made to meet the pharmacopeia or API impurity requirements for drug development. The purity of this compound ranges from 98% to 100%. This compound is used in HPLC standards for research and development purposes such as metabolism studies.</p>Formule :C21H26N2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :402.44 g/mol2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid ethyl ester hydrobromide
CAS :2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid ethyl ester hydrobromide is a drug development impurity that belongs to the group of API impurities. It is an impurity standard for HPLC and also appears as a metabolite in animal studies. This compound has been shown to have a high purity and can be used as a custom synthesis or analytical standard. 2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid ethyl ester hydrobromide is also an impurity in the drug product called "NOVOQUINOL". The compound has been found to be an intermediate in metabolism studies.Formule :C12H14BrCl2N3O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :383.07 g/mol5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole
CAS :<p>5-Methoxy-2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H benzimidazole is a synthetic drug product. It has been used as a positive control in metabolism studies and as an impurity standard. 5-Methoxy 2-[(4-chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfinyl]-5 methoxy 1H benzimidazole is also a metabolite of the active pharmaceutical ingredient (API) which is used to develop drugs. This chemical is synthesized by custom synthesis and can be obtained at high purity levels. The metabolite of this compound is 5 methoxy 2-[(4 chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfonyl]-5 methoxy 1H benzimidazole.</p>Formule :C16H16ClN3O2SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :349.84 g/mol2-Phenylbutyric acid
CAS :<p>2-Phenylbutyric acid is a product of the oxidation of phenylacetic acid by flavus. 2-Phenylbutyric acid is an inhibitor of contactor reactions that use α1-acid glycoprotein as a chromatographic support. It has been shown to inhibit the reaction mechanism of extractants (e.g., butamirate citrate) with enantiomeric compounds (e.g., creatine). It also inhibits subclinical mastitis in cows and fatty acid synthesis, leading to decreased cholesterol synthesis in humans.</p>Formule :C10H12O2Degré de pureté :Min. 95%Masse moléculaire :164.2 g/mol[5-[(Dimethylamino)methyl]furan-2-yl]methanethiol, oxalate
CAS :<p>5-[(Dimethylamino)methyl]furan-2-yl]methanethiol, oxalate is a chemical compound with the molecular formula of C4H8O2S. It is a colorless to pale yellow liquid that is soluble in water and ethanol. This product is used as an impurity standard for HPLC analysis of drugs and as a synthetic intermediate in the drug development process. 5-[(Dimethylamino)methyl]furan-2-yl]methanethiol, oxalate can be synthesized from furfuryl alcohol and methylamine under mild conditions. The purity of this product can be determined by HPLC analysis or GCMS analysis.</p>Formule :C8H13NOS·C2H2O4Degré de pureté :Min. 95%Masse moléculaire :261.3 g/molSitagliptin Diamide impurity
<p>Sitagliptin Diamide Impurity is a drug product that is a white crystalline powder. It has been developed as an analytical standard for the impurity Sitagliptin Diamide. The impurity is a metabolite of sitagliptin, which is an oral antidiabetic drug used to treat type 2 diabetes. Sitagliptin Diamide Impurity can be used as a pharmaceutical intermediate and in research and development.</p>Formule :C20H19F6N5O3Degré de pureté :Min. 95%Masse moléculaire :491.39 g/mol5-Nitro-2-furfuraldazine
CAS :<p>5-Nitro-2-furfuraldazine (5NFD) is a retested, statistically significant carcinogen that has been shown to cause mammary tumors in female rats. 5NFD is a nitrosamine and a formamidine. It has been shown to have biological activity as an inhibitor of mitosis in fibroadenomas and mammary tumors. It inhibits mitosis by inhibiting DNA synthesis and protein synthesis, which leads to the death of tumor cells. 5NFD has also been found to induce pleomorphism in human lymphocytes.</p>Formule :C10H6N4O6Degré de pureté :Min. 99 Area-%Couleur et forme :PowderMasse moléculaire :278.18 g/mol5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide
CAS :<p>5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulphonyl]-1H-benzimidazole N-oxide is a cyclic sulfoxide that has shown to be a potent inhibitor of gastric acid secretion. It is an important intermediate in the synthesis of esomeprazole magnesium, a proton pump inhibitor used to treat gastroesophageal reflux disease and other gastrointestinal disorders. 5-Methoxy-2-[(4-methoxy 3,5 dimethyl 2 pyridinyl) methyl] sulphonyl]-1H benzimidazole N oxide is also known as (RS)-N-[4-(4′ methoxyphenyl)-3,5 dimethylpyrazol -2 - ylmethyl] methanesulfonamide. This compound has been shown to have a polymorphic form with two different</p>Formule :C17H19N3O5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :377.42 g/molCimetidine impurity F
CAS :<p>Cimetidine impurity F is a research and development, drug product, analytical, synthetic, natural, niche, HPLC standard and pharmacopoeia impurity.<br>CAS No. 55272-86-1</p>Formule :C16H24N8S2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :392.55 g/molHomo sildenafil
CAS :<p>Analogue of sildenafil</p>Formule :C23H32N6O4SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :488.6 g/mol3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanoic acid
CAS :<p>3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanoic acid is a pharmaceutical agent. It is used in the treatment of heartburn, gastroesophageal reflux disease (GERD), and other conditions. 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanoic acid is a prodrug that is hydrolyzed to famotidine, its active form, in the body. Famotidine has been shown to inhibit the H+/K+ ATPase enzyme from gastric parietal cells, which increases intracellular pH and reduces gastric acid secretion. 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanoic acid also inhibits</p>Formule :C8H12N4O2S2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :260.34 g/mol2,3,4-Trimethoxybenzyl alcohol
CAS :<p>2,3,4-Trimethoxybenzyl alcohol is a photooxidant that is used in pharmaceutical formulations. It has a catalytic effect on the photooxidation of trifluoroacetic acid and is used for the production of fluoroquinolones. It can also be used to produce other pharmaceutical compounds such as antibiotics and anti-cancer drugs. 2,3,4-Trimethoxybenzyl alcohol is found in small quantities in many natural products such as fruits and vegetables. It has been shown to have potential impurities including 4-methoxybenzaldehyde and selectivity modifiers.</p>Formule :C10H14O4Degré de pureté :Min 96.5%Couleur et forme :Clear LiquidMasse moléculaire :198.22 g/mol3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanamide
CAS :<p>3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanamide is a synthetic drug product. It is not found in natural products and it has no pharmacopoeia name. 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanamide is an impurity standard for the manufacture of pharmaceuticals. It is also used as a research and development reagent and analytical standard. 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanamide has not been evaluated by the FDA as a food additive, but it has been evaluated by the European Union as a flavoring agent.</p>Formule :C8H13N5OS2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :259.35 g/molRabeprazole
CAS :<p>Rabeprazole is a proton pump inhibitor that suppresses the production of stomach acid by blocking the H+/K+ ATPase enzyme. It is used for the treatment of gastroesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome. Rabeprazole has been shown to be more effective than omeprazole in reducing gastric acid secretion in two-way crossover studies. Rabeprazole also has been shown to inhibit the growth of antibiotic-resistant strains of bacteria. In addition, rabeprazole binds to metal ions like iron and copper, which may affect its pharmacokinetics and efficacy. This drug is currently being investigated as an analytical method for determination of proton pump inhibitors in human serum and urine samples by electrochemical impedance spectroscopy (EIS).</p>Formule :C18H21N3O3SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :359.44 g/mol4-Desmethoxy omeprazole sulfide
CAS :<p>4-Desmethoxy omeprazole sulfide is a metabolite of omeprazole, a drug that is used to treat ulcers and gastroesophageal reflux disease. 4-Desmethoxy omeprazole sulfide is not an impurity in the production of omeprazole, but is present as a natural component of omeprazole. This compound has been shown to be an impurity standard for HPLC analysis. The pharmacopoeia defines 4-desmethoxy omeprazole sulfide as an API impurity in drug products. It is also being studied for its potential use in drug development and research and development.</p>Formule :C16H17N3OSDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :299.39 g/mol2,6-Dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid isopropyl 2-methoxyethyl ester
CAS :<p>Nimodipine is a calcium channel blocker that is used to treat subarachnoid hemorrhage and aneurysms. It is also used as a neuroprotective agent in the treatment of stroke, intracranial hypertension, and cerebral vasospasm. Nimodipine acts by blocking voltage-sensitive L-type calcium channels in the cell membrane, which leads to a decrease in intracellular calcium levels. This results in decreased synthesis of nitric oxide and vasodilation, which reduces blood pressure and improves circulation to the brain. Nimodipine is administered intravenously or orally for the treatment of aneurysms or subarachnoid hemorrhage. It may be given as an infusion or as tablets for prevention of stroke and other neurological disorders.</p>Formule :C21H24N2O7Degré de pureté :Min. 95%Couleur et forme :Slightly Yellow PowderMasse moléculaire :416.42 g/molBisoprolol impurity K
CAS :<p>Bisoprolol impurity K is a drug product that is an analytical standard used for the detection and identification of bisoprolol in pharmaceutical products. It is a synthetic impurity with CAS No. 864544-37-6 that does not have any pharmacological activity. Bisoprolol impurity K is a high purity HPLC standard that can be used to develop analytical methods for the determination of bisoprolol in pharmaceutical products.</p>Formule :C18H29NO5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :339.43 g/mol7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one
CAS :<p>7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one is a palladium catalyst that can be used in a Buchwald reaction. This reaction is an industrially scalable process that has been developed to produce high yields of valuable organic compounds from inexpensive starting materials. The catalytic cycle involves the formation of the palladium species Pd(0) followed by its oxidative addition to an alkyl halide. This addition leads to the formation of a palladium(II) species and subsequent reductive elimination of hydrogen halide. 7-(4-Bromobutoxy)-3,4-dihydroquinolin-2-one is used as a catalyst in this process because it selectively reacts with electron rich aromatic substrates to form substituted benzoquinones or phenols. The product distribution is determined by the reactivity of the substrate and the relative rates of competing reactions. Impurities are formed during synthesis due to</p>Formule :C13H16BrNO2Degré de pureté :Min. 95%Masse moléculaire :298.18 g/mol2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole
CAS :<p>Rabeprazole is a proton pump inhibitor that is used to treat acid-related disorders such as gastroesophageal reflux disease and peptic ulcers. Rabeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium ATPase that is found in the parietal cells of the stomach. The main mechanism of action for rabeprazole is competitive inhibition of the proton pump, which leads to decreased gastric acid secretion. Rabeprazole can be administered orally or intravenously, with a half-life of about 2 hours. It has been shown to have an effect on human liver cytochrome P450s, but does not affect the activity of recombinant cytochrome P450 3A4 (CYP3A4). In clinical studies, rabeprazole was shown to have no adverse effects on CYP3A4 activity and may even increase it slightly.</p>Formule :C18H21N3O2SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :343.44 g/mol2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene
CAS :<p>2-(N-Methyl-propanamine)-3-(2-naphthyl) thiophene is a synthetic compound that has been used as an impurity standard for the drug product and API. It has also been used for the pharmacopoeia, research and development, and analytical purposes. This compound is a metabolite of erythromycin.</p>Formule :C18H19NOSDegré de pureté :Min. 95%Couleur et forme :White To Pink Or Yellow SolidMasse moléculaire :297.42 g/mol
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