Monosaccharides

<p>UDP-L-galactose diammonium salt is a modification of the sugar UDP-galactose. It is an oligosaccharide that is found in glycoproteins and glycolipids. It is synthesized by the addition of a methyl group to the galactose ring and a fluorine atom to the hydroxyl group on carbon 4. UDP-L-galactose diammonium salt is used as a synthetic sugar in laboratory settings, although it can also be found in nature. This compound has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>An anhydro thio sugar</p>

<p>Chiral synthon; used to synthesise analgoues of natural products</p>

<p>3-O-Benzyl-1,2-O-isopropylidene-a-D-glucofuranose (3BZIPF) is an oligosaccharide with a molecular weight of 477.6 g/mol. It is soluble in alcohol and water. 3BZIPF can be used as a sugar substitute or in the food industry. The product can be custom synthesized to meet your requirements.</p>

<p>a-D-Glucoheptonic acid sodium salt is a compound that has been shown to modulate the immune system. It also has been used in pharmaceutical formulations as an excipient and as a carrier for diagnostic and therapeutic agents.</p>

<p>3-Deoxy-3-fluorosucrose is a noncompetitive inhibitor of leuconostoc mesenteroides glucosyltransferases. It inhibits the enzyme by binding to the active site and preventing the transfer of glucose from the sugar transport to the acceptor. 3-Deoxy-3-fluorosucrose has been shown to inhibit the synthesis of pro-inflammatory cytokines, such as TNF-α and IL1β, in vitro. This inhibition is thought to be due to its ability to inhibit sugar transport and thus prevent glycosylation reactions that are required for protein synthesis.</p>

<p>2-Acetamido-2-deoxy-D-talopyranose is a noncompetitive inhibitor of the enzyme glycosidase. It has been shown to inhibit the enzymatic cleavage of glycoconjugates, such as glycoproteins and glycolipids, as well as antigen binding. 2-Acetamido-2-deoxy-D-talopyranose binds to the receptor binding domain on the surface of cancer cells and inhibits the growth of these cells in vitro. This compound also has potent inhibitory activity against influenza virus and is used in the synthesis of glycans for use in vaccines. 2-Acetamido-2-deoxy-D-talopyranose can be produced through acid hydrolysis or enzymatic methods.</p>

<p>2-O-a-D-Galactopyranosyl-1-deoxynojirimycin is a monosaccharide derivative of deoxynojirimycin. It is synthesized by the methylation of the natural product, followed by the addition of a click modification and the fluorination of one sugar. This compound has been shown to have anti-inflammatory properties, as well as inhibitory effects on bacterial growth.</p>

<p>L-Arabinose-BSA is a Glycosylation, Oligosaccharide, sugar, Synthetic, Fluorination, Custom synthesis, Methylation, Monosaccharide, Polysaccharide, saccharide. It is a Click modification. L-Arabinose-BSA has CAS No. 1590-84-3 and Modification of complex carbohydrate. This product has High purity.</p>

<p>Mannide monooleate is a naturally occurring fatty acid that is found in the lipid bilayer of cell membranes. It has shown to be effective in the treatment of a number of chronic inflammatory diseases, such as arthritis and inflammatory bowel disease. Mannide monooleate is also being explored as an adjuvant for vaccines, and has shown efficacy against leishmania infection.</p>

<p>Sophorolipids are produced by various yeast species, notably Starmerella bombicola. Acidic Sophorolipids are amphiphilic molecules and therefore possess the attributes of surfactants; however as bio-surfactants they have several advantages over synthetic surfactants including low toxicity, biodegradability and the potential for low cost manufacture.</p>

<p>Methyl β-L-arabinopyranoside is a monomer that is used for the synthesis of polymers. It has been shown to be an effective polymerization catalyst, with long-term stability and good storage properties. Methyl β-L-arabinopyranoside has been used in gas chromatographic analysis as an analyte to identify hydroxy groups, although it may also interfere with the detection of certain other analytes. This monomer is often used in the production of plastics and rubbers because it enhances bonding between rubber molecules and plasticizers. Methyl β-L-arabinopyranoside has also been shown to have tailing enhancements and extracts that are due to hydroxy groups, which can lead to signal enhancement in gas chromatography. Additives such as ammonium acetate can be added if there is a need to increase sensitivity or reduce tailing effects.</p>

<p>Sustainable solvent used widely in cosmetic and pharmaceutical formulations</p>

<p>4-Hydroxypropofol 1-O-b-D-glucuronide is a metabolite of propofol that is found in human urine. It can be detected by chromatography and UV spectroscopy. 4-Hydroxypropofol 1-O-b-D-glucuronide has been shown to have radical scavenging activity and can be used as an analytical reagent for the validation of analytical methods. This compound has also been analysed for its cytotoxic and antiinflammatory effects on the cytosol of cultured cells, with promising results.</p>

<p>L-Threonic acid-1,4-lactone is a nutrient solution for mammalian tissue. It is a coenzyme that acts as an intermediate in the conversion of dehydroascorbic acid to erythronate and participates in the synthesis of 4-hydroxycinnamic acid from 4-hydroxyphenylpyruvic acid. L-Threonic acid-1,4-lactone has been shown to inhibit the replication of human immunodeficiency virus (HIV) in vitro. The physiological levels of L-Threonic acid-1,4-lactone are not yet known, but it has been shown to have inhibitory properties on HIV infection at concentrations that do not affect cellular metabolism or induce reactive oxygen species production. L-Threonic acid-1,4-lactone also has been shown to prevent hepatic steatosis and fatty liver disease by inhibiting lipid accumulation via its ability to</p>

<p>DL-Xylose is a sugar that belongs to the group of pentoses. It contains a hydroxyl group at the C2 position and an aldehyde group at the C1 position. DL-Xylose is found in plants, animals, and bacteria. The gene sequence analysis of the type strain of DL-xylose showed that it has a fatty acid composition of 0.5% and protocatechuic acid composition of 0.7%. Dry weight analysis on swiss-webster mice fed with DL-xylose as the only carbon source showed that this sugar can provide up to 30% of energy requirements for these mice.</p>

<p>2-(D-Gluco-pentylhydroxypentyl)-4(R)-1,3-thiazolidine-4-carboxylic acid is a custom synthesis. It is used in the glycosylation of saccharides and oligosaccharides. This product can be modified with fluorination, methylation, or click modification. It is also used in the synthesis of complex carbohydrates.</p>

<p>Silodosin O-beta-D-glucuronide is a metabolite of silodosin, a drug used to treat benign prostatic hyperplasia. It is the glucuronide conjugate of silodosin and its presence in plasma can be quantified by high performance liquid chromatography (HPLC). The solvents used in HPLC are acetonitrile and ammonium formate. The chromatographic separation is achieved with a mobile phase consisting of an organic solvent (acetonitrile) and an ion pairing agent (ammonium formate) that interacts with the analyte and forms an ion pair. The sensitivity of HPLC for this analyte can be improved by using deuterated solvents.</p>

<p>2,3,4,6-Tetra-O-acetyl-a-D-galactopyranosyl trichloroacetimidate is a disaccharide that is an activated glycoprotein. It is used as a hapten for the production of monoclonal antibodies and as an immunogen in stepwise immunization with bovine serum albumin. This compound has been shown to be specific for the EGF receptor on neoglycoproteins and can be used to detect this receptor. The glycosidic residue of 2,3,4,6-tetra-O-acetyl-a-D-galactopyranosyl trichloroacetimidate allows it to bind to proteins such as albumin and act as a carrier for other molecules.</p>

<p>Methyl 2,3,4,6-tetra-O-benzyl-a-D-mannopyranoside is a glycosylation product that can be used in chemical synthesis. This compound is an example of a complex carbohydrate and can be modified with methyl or fluorine groups. Methyl 2,3,4,6-tetra-O-benzyl-a-D-mannopyranoside is also a sugar and an oligosaccharide. This compound has been custom synthesized to meet customer specifications and is available in high purity.</p>

<p>L-Glycero-D-manno-heptose is a polymyxin B antimicrobial agent that has been shown to have significant activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae. This compound also has an inhibitory effect on the growth of Gram-negative species such as Salmonella enterica. L-Glycero-D-manno-heptose inhibits the synthesis of bacterial cell wall peptidoglycan by binding to the terminal residues of oligosaccharides, which are linked to D-alanine in the peptidoglycan chain. The terminal residues of oligosaccharides are transferred from the lipid carrier to L-glycero-D manno heptose, forming a stable acylated glycoside. This reaction mechanism is similar to that of polymyxin B, but with a difference in reactivity due to steric hindrance.</p>

<p>N-Acetyl-D-quinovosamine is a chemical compound that belongs to the group of quinovosamines. It is an acidic molecule with a pKa of 3.5 and is soluble in water, methanol, and acetic acid. N-Acetyl-D-quinovosamine has been shown to inhibit the growth of P. aeruginosa strains, which are human pathogens. This drug binds to the bacterial cell wall by competitive inhibition and prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. N-Acetyl-D-quinovosamine also inhibits the production of hydrogen fluoride (HF) by bacteria as well as their ability to produce ammonia from nitrite or nitrate ions.</p>

<p>3,4,6-Tri-O-benzyl-2-nitro-D-galactal is a nitro compound that is used in the synthesis of glycopeptide antibiotics. It reacts with threonine, forming an intramolecular hydrogen bond to yield the corresponding methyl ester. The nitrate ion can also be used as a nucleophile to form an ether with alcohols or amines. This reaction is stereoselective and yields the desired product in high yields.</p>

<p>Phenyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside (TTA) is a synthetic monosaccharide that is used in the synthesis of complex carbohydrates. TTA is also known as Fluorination, Monosaccharide, Synthetic, Oligosaccharide, complex carbohydrate and has CAS No. 2872-72-2. TTA can be custom synthesized for research purposes or for commercial use and can be glycosylated to form polysaccharides. TTA is modified through methylation or click chemistry and can be used to modify sugar molecules or other carbohydrates. It is also high purity with less than 1% impurities.</p>

<p>Benzoic acid-acyl-b-D-glucuronide is a β-glucuronide linker that is cleaved by β-glucuronidase enzymes. This allows controlled release of the payload to the targeted cells.</p>

<p>L-Sorbose-1-phosphate potassium salt is a sugar phosphate</p>

<p>N-Acetyl-9-azido-9-deoxy-neuraminic acid (also known as 9AzNeu5Ac) is used as a sialic acid substitute for metabolic glycan labelling, which allows glycan-protein interactions and sialylations to be interrogated. Naturally occurring glycans can be di-sialylated by sialidase and replaced by a sialyl analogue, such as N-acetyl-9-azido-9-deoxy-neuraminic acid, using sialyltransferase. The modified glycans are then resistant to sialidase. Reduction of the azide functionality of N-acetyl-9-azido-9-deoxy-neuraminic acid affords access to an additional 9-amino sialic acid analogue which can be further elaborated to 9-amido analogues.</p>

<p>1-Chloro-2-deoxy-3,5-di-O-toluoyl-L-ribofuranose is a synthetic glycosylation agent with high purity and custom synthesis. It is a monosaccharide that can be used for the modification of complex carbohydrates, such as saccharides and polysaccharides. 1-Chloro-2-deoxyribofuranose is also known to react with other types of sugars to form glycosylated products. This product can be fluorinated or methylated to create new derivatives.</p>

<p>L-Gulurono-6,3-lactone is a methylated carbohydrate that can be modified with a variety of functional groups. It is used in the synthesis of saccharides and oligosaccharides. L-Gulurono-6,3-lactone has been shown to bind to a variety of proteins, including amyloid beta protein and human serum albumin.<br>This compound is synthesized by reacting L-glucose with 2 equivalents of anhydrous hydrogen fluoride in acetic acid at room temperature. It is also fluorinated by reacting it with sodium borohydride and hydrogen fluoride in methanol at -78°C.</p>

<p>Octyl D-galactofuranoside is a disaccharide that is found in the plant Gossypium hirsutum. It has been shown to have antibacterial activity and can be used as an alternative to antibiotics. Octyl D-galactofuranoside has been shown to inhibit the growth of bacteria by binding to chloride ions and inhibiting bacterial cell wall synthesis. It also acts synergistically with other antibiotics, such as penicillin, ampicillin, sulfonamides, tetracycline, erythromycin, and cefadroxil. This compound has been shown to be biodegradable and o-glycosylated. Octyl D-galactofuranoside also has anti-leishmanial activity.</p>

<p>Diclofenac acyl-D-glucuronide is a nonsteroidal anti-inflammatory drug that inhibits the enzyme activity of aminotransferase. This leads to a decrease in the production of prostaglandins, which are responsible for the inflammatory response. Diclofenac acyl-D-glucuronide has been shown to have antiulcer effects in vitro and in vivo. It also decreases the uptake of diclofenac by human tubule cells, which may be due to its reactive nature. The clinical relevance of this drug is still under investigation, but it is believed that diclofenac acyl-D-glucuronide could play a role in wastewater treatment because it can be easily extracted from water samples with analytical chemistry techniques.</p>

<p>Oroxylin A 7-O-glucuronide (OA7G) is a natural compound that exhibits anti-angiogenic and anti-inflammatory effects. OA7G binds to p-hydroxybenzoic acid and inhibits the activity of glycosidases, which are enzymes that hydrolyze glycosides. OA7G has been shown to have therapeutic potential in several models of inflammatory bowel disease. In vivo studies show that OA7G may be a useful agent for the treatment of bowel disease by inhibiting angiogenesis, which is the formation of new blood vessels from pre-existing ones. Molecular docking analysis showed binding affinity between OA7G and the enzyme dextran sulfate glucuronyltransferase, suggesting a possible mechanism for its anti-inflammatory effects.</p>

<p>13-cis-Retinoyl b-D-glucuronide is a synthetic compound that can be modified to create a wide range of potential products. 13-cis-Retinoyl b-D-glucuronide is an oligosaccharide with a carbohydrate that may be glycosylated or polysaccharided. It has been custom synthesized and fluorinated, methylated, and monosaccharided. This product is extremely pure and can be used for many applications in the biomedical field.</p>

<p>Methyl 3,5-di-O-acetyl-2-deoxy-D-ribofuranoside is a synthetic, fluorinated monosaccharide. It is an important building block for the synthesis of complex carbohydrates. The compound is also used for glycosylation reactions, click modification reactions and methylation reactions. Methyl 3,5-di-O-acetyl-2-deoxy-D-ribofuranoside can be used as an intermediate to make other products or as a custom synthesis.</p>

<p>Building block for DNA-related organic synthesis</p>

<p>D-Glycero-D-talo-heptitol is a natural product that is found in plants and bacteria. It is an alditol, which is created by the glycosidic bond of a carbohydrate and a hydroxyl group. D-Glycero-D-talo-heptitol has shown to inhibit the activity of enzymes involved in fatty acid synthesis, such as 3-hydroxyacyl coenzyme A dehydrogenase, and carbohydrate synthesis, such as fructose 1,6 bisphosphatase. This compound also inhibits the borohydride reduction of glycan precursors. This may be due to its hydrophilic interactions with water molecules and its hydrophobic interactions with other lipid molecules.</p>

<p>An anhydro thio sugar</p>

<p>2,3,4,6-Tetra-O-acetyl-4-(hydroxymethyl)phenyl-b-D-glucopyranoside is a chemical that is extracted from the rhizoma gastrodiae. It is used to treat symptoms of damaged ganglion cells in diabetic patients. 2,3,4,6-Tetra-O-acetyl-4-(hydroxymethyl)phenyl-b-D-glucopyranoside inhibits chloride channels in neurons by binding with the extracellular receptor site and thereby preventing the influx of chloride ions. This leads to reduced neuronal excitability and decreased symptoms of damaged ganglion cells in diabetic patients. 2,3,4,6 Tetra O acetyl 4 (hydroxymethyl) phenyl b D glucopyranoside has been shown to have an inhibitory effect on structural formula and environmental pollution.</p>

<p>The anomeric position of 2,3,4-tri-O-benzyl-L-arabinopyranose is anomeric. The yields of the two possible anomers were not determined in this experiment. Hydrogenolysis of the benzyl group in 2,3,4-tri-O-benzyl-L-arabinopyranose at room temperature resulted in a mixture of the two possible anomers.</p>

<p>2-Aminophenyl b-D-glucuronide is a cytosolic drug that is metabolized by the liver to mandelonitrile, which is then excreted in urine. 2-Aminophenyl b-D-glucuronide has been shown to inhibit the growth of fungi in vivo and has been shown to have a reversible binding affinity for fungal cell walls. This drug also inhibits the production of ergosterol, an important component of fungal cell membranes, which leads to cell death.</p>

<p>UDP-N-acetyl-D-mannosamine is a precursor of the sugar nucleotide UDP-N-acetylglucosamine. It is synthesized in the cytoplasm by the enzyme UDP-N-acetylglucosamine 2-epimerase, which converts UDP-N-acetylglucosamine to UDP-N-acetylmannosamine. This enzyme also catalyzes the conversion of UDP-N-[3′,5′]-diacetamido mannosamine to UDP-[3′,5′]-diacetamido glucuronic acid. The enzyme has been found in Streptococcus spp., including Streptococcus pneumoniae and Streptococcus pyogenes serogroup A (group A streptococci). It has also been detected in other bacteria, including Neisseria meningitidis and Staphylococcus aureus.</p>

<p>1,4:3,6-Dianhydro-2-O-acetyl-D-glucitol is an isosorbide intermediate</p>

<p>3,4,5,6-Tetra-O-benzyl-myo-inositol is a chiral molecule that is synthesised by the reaction of 3,4,5,6-tetra-O-benzylglycerol with myo-inositol. It has been used as an optical probe to study the function of biomolecules such as membranes and reticulum. The compound was also shown to inhibit the phosphorylation of myosin light chain kinase.</p>

<p>Benzyl a-D-mannopyranoside is a pharmaceutical dosage form of the drug benzyl a-D-mannopyranoside, which is used to control analysis of silver trifluoromethanesulfonate. It is administered orally as a monosodium salt, which is the only form that has been studied in humans. This combination therapy group was found to be more effective than benzyl groups or systematically administered drugs when used as monotherapy. Benzyl a-D-mannopyranoside may be glycosidated by cells in culture and this process may cause symptoms such as nausea and vomiting. However, glycosidation does not occur in humans.</p>

<p>1,2-O-Isopropylidene-3-deoxy-a-D-allofuranose is a custom synthesis that is a complex carbohydrate. It has been modified by methylation and glycosylation. The product is an Oligosaccharide, Polysaccharide and Modification of saccharide. The product has high purity with a CAS No. 4494-96-6.</p>

<p>L-Threonic acid is a metabolite of plants that is involved in the synthesis of other molecules. It can be found in the injection solution and magnesium salts that are used for treating osteoporosis and magnesium deficiency. L-Threonic acid can also be found in caffeic acids, which are plant polyphenols that have antioxidant properties. L-Threonic acid has been shown to have structural similarity to calcium and has been shown to have a role in mitochondrial membrane potential, cellular physiology, and oxidative injury. L-Threonic acid may also play a role in energy metabolism. The toxicity of L-Threonic acid has been studied extensively with mixed results.</p>

<p>1,2-O-Isopropylideneglycerol is an inhibitor of glycerin and glycerol dehydrogenase. It is a colorless liquid that has been shown to have a kinetic inhibitory effect on the enzyme activities of glycerin and glycerol dehydrogenase in vitro. 1,2-O-Isopropylideneglycerol has also been shown to react with light at wavelengths of 250 nm or less. This reaction produces reactive oxygen species that may lead to the degradation of the enzyme's active site. In vivo, 1,2-O-isopropylideneglycerol is converted into an acidic metabolite that can accumulate in cells. This metabolite can react with other molecules such as proteins and nucleic acids, which may result in structural changes and/or modification of their function.</p>

<p>Competitive inhibitor of fucosyltransferases FUT3, FUT5, FUT6 and FUT7 with Ki values in low micromolar range. This fluorinated GDP-fucose analog inhibits oligosaccharide core fucosylation of N-linked glycans in animal and plant cells.</p>

<p>4-Aminophenyl β-D-Glucuronide can be used to analyse acetaminophen and other metabolites in plasma.</p>

<p>2-Acetamido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-b-D-glucopyranosyl azide is a modified carbohydrate that is used in the synthesis of glycosides. It is a synthetic molecule that is fluorinated at the alpha position of the glycosidic bond to allow for reaction with other molecules. This product has been shown to be stable in acid and base reactions and can be used for oligosaccharide synthesis or modification.</p>

<p>1,6-Dichloro-1,6-dideoxy-D-fructose (1,6DD) is a synthetic spermicide that prevents the fusion of the egg and sperm. It has been shown to be effective in reducing fertility in male rats. The pharmacological effects of 1,6DD are due to its benzalkonium chloride content. 1,6DD is a reactive chemical that can damage cellular membranes and lead to cell death. Benzalkonium chloride is toxic to human cells and can cause necrosis or apoptosis. The toxicity of 1,6DD on the brain has been demonstrated using human liver cells as well as human brain cells. This agent also has an effect on mineralization and causes an increase in calcium influx into cells by activating calcium channels.</p>

<p>2-Acetamido-2,4-dideoxy-4-fluoro-a-D-glucopyranose is a synthetic, fluorinated carbohydrate. It is a monosaccharide that is made by the substitution of an acetamido group with a fluoro group at C2 and C4 of the glucose molecule. This product has been synthesized using Click chemistry to modify the 2’ position and methylation at C5. The target use for this product is as a sugar in order to glycosylate or polysaccharide. This compound has been shown to have high purity and can be custom synthesized, depending on the needs of the customer.</p>

<p>2-O-a-D-Glucopyranosyl-L-ascorbic acid is a potent antioxidant compound found in the human body. It is produced by the enzyme tyrosinase from L-ascorbic acid and has been shown to have anti-apoptotic effects on skin cells. 2-O-a-D-Glucopyranosyl-L-ascorbic acid has also been shown to enhance mitochondrial membrane potential and increase the proliferation of skin cells in vitro. The compound has been tested for its ability to prevent radiation damage in mice and was found to be more effective than vitamin C at preventing cell death.<br>2OAGA can be used as a topical treatment for skin conditions, such as acne or wrinkles, by reducing inflammation and stimulating cellular growth.</p>

<p>L-Sorbitol is a polyhydric alcohol that is found in various natural products, such as fruits and vegetables. It has been shown to inhibit the growth of strains of Stenotrophomonas maltophilia, which is an opportunistic pathogen of human and animal cells. L-Sorbitol can be used to treat bacterial infections by inhibiting the synthesis of DNA, RNA, and proteins. This compound has also been shown to prevent dehydration in bacteria by acting as an osmotic agent. The effect of L-sorbitol on the growth of bacteria depends on the pH of the environment in which it is dissolved. The optimum pH for this compound is 7.5</p>

<p>Ethyl a-D-glucopyranoside is an organic acid that has been extracted from the seeds of the plant Reticulata. It contains a mixture of fatty acids and compounds that are collectively known as retinoids. Ethyl a-D-glucopyranoside inhibits beta-glucosidase, aminotransferase activity, and intestinal glucosidases and has been shown to have antioxidant properties. This product may be used for the treatment of musculoskeletal disorders, such as osteoarthritis, which is characterized by degeneration and inflammation of joints. Ethyl a-D-glucopyranoside may also be used as an agent to help prevent skin aging caused by exposure to ultraviolet (UV) radiation and other factors.</p>

<p>1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose is a per-O-acetylated version of 5-alkynyl-L-fucose, an inhibitor of the cellular fucosylation pathway. 1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose can pass through the eukaryotic cell membrane somewhat better than 5-alkynyl-L-fucose can itself, is deacetylated by cellular esterases and interferes with the biosynthesis of the fucosyl-donor and fucosyltransferase substrate GDP-Fuc, thus reducing fucosylation levels during glycoprotein biosynthesis (Dekkers, 2016).</p>

<p>Candesartan N-glucuronide is a metabolite of candesartan. It is produced by human UDP-glucuronosyltransferase, which belongs to the subfamily of uridine diphosphate (UDP)-glucuronosyltransferases. Candesartan N-glucuronide inhibits angiotensin II receptor type 1 (AT1) and has minimal effects on angiotensin II receptor type 2 (AT2). Candesartan N-glucuronide binds to the AT1 receptor and blocks its activation by angiotensin II. This binding inhibits the uptake of sodium ions into cells and causes an increase in potassium ion secretion, leading to vasodilation. Candesartan N-glucuronide also induces the expression of cytochrome P450 3A5, which results in increased metabolism of drugs such as paclitaxel.</p>

<p>Methyl b-L-fucopyranoside is a glycosylating agent that is used to modify saccharides and oligosaccharides. It can be used for the synthesis of complex carbohydrates, such as polysaccharides and glycoconjugates. Methyl b-L-fucopyranoside is also useful for the synthesis of glycosylated proteins, which are proteins with sugar chains attached to them. The product is a white solid that is soluble in water.</p>

<p>1,4-Anhydro-D-mannitol is a sugar alcohol that belongs to the group of alditols. It is a tautomer of galactitol, which is found in fetal bovine serum. The dehydrated form of this compound has been shown to have an inhibitory effect on tyrosinase activity. 1,4-Anhydro-D-mannitol may be used as an intermediate in the production of polymers or as a cosmeceutical agent due to its high water solubility and low toxicity.</p>

<p>D-[UL-¹³C6]mannose is a research chemical that is widely used in the field of carbohydrate and protein studies. It is a heavy label isotope of mannose, a monosaccharide that plays an important role in various biological processes. D-[UL-¹³C6]mannose is commonly used to study the metabolism and biosynthesis of oligosaccharides, glycoproteins, and lipopolysaccharides. By incorporating this heavy label into these molecules, researchers can track their movement and interactions within cells and tissues. This research chemical is an invaluable tool for studying the complex structures and functions of carbohydrates in biological systems.</p>

<p>Methyl 2,3,5-tri-O-benzyl-D-ribofuranoside is a potential drug that can be used in the treatment of type 2 diabetes. It is an analog of curcumin that has a nucleophilic group on its benzyl ring. This group reacts with the carbonyl carbon atom in maltase glucoamylase and triggers a Friedel-Crafts reaction that generates an isomeric product. The methyl 2,3,5-tri-O-benzyl-D-ribofuranoside molecule inhibits glycosidases by binding to the active site of these enzymes and preventing access to substrate. Methyl 2,3,5-tri-O-benzyl-D ribofuranoside has also been shown to have antifungal activity against Candida albicans.</p>

<p>3-Phenyl-2-propenylbeta-D-glucopyranoside is a flavonoid that has been shown to have inhibitory properties. It has been used as an analytical method for the diagnosis of bronchial reactivity. The high resistance of 3-phenyl-2-propenylbeta-D-glucopyranoside to oxidation and reduction make it an interesting candidate for antiinflammatory agents. When testing the effects of this compound on human bronchial tissue, it was found that 3-phenyl-2-propenylbeta-D-glucopyranoside inhibited allergic symptoms by inhibiting the release of inflammatory mediators such as histamine and leukotrienes, which are released in response to allergens and other irritants in the airways. The use of this compound may be useful in the treatment of asthma patients who suffer from allergic reactions to dust, pollen, or animal dander.</p>

<p>Raloxifene 6,4'-bis-b-D-glucuronide is a synthetic molecule that has been modified and fluorinated. It is a monosaccharide with a methyl group at C6. The synthesis of this compound starts with the conversion of raloxifene to the bis-b-D-glucuronide compound in which hydroxyl groups have been esterified by an acetyl group. The modification process includes the addition of a methyl group at C6, and then it is fluorinated. This product is soluble in water and methanol, but insoluble in ether. It has CAS number 182507-20-6 and molecular weight 536. Raloxifene 6,4'-bis-b-D-glucuronide can be used as an intermediate for the synthesis of oligosaccharides or polysaccharides.</p>

<p>Intermediate for β-glucosides; potential PET surface modification reagent</p>

<p>S-(-)-Perillyl alcohol glucoside is a glycoconjugate that has been shown to inhibit β-glucosidase and pancreatic lipase. It is used in the treatment of cancers, such as colorectal cancer, by inhibiting glucose uptake into cells. S-(-)-Perillyl alcohol glucoside may also have anticancer effects by inhibiting glucose transporters and caspases.</p>

<p>UDP-D-glucuronide ammonium salt is a drug that is used for the treatment of estrogen-dependent cancers. It is an inhibitor of human UDP-glucuronosyltransferase, an enzyme that catalyzes the glucuronidation of estrone and other substrates. The binding affinity of UDP-D-glucuronide ammonium salt can be increased by mutating the enzyme to increase its kinetic rate. This drug has been shown to inhibit estrogen production in recombinant human liver cells as well as in human liver cells. Mutations in the gene encoding this enzyme have also been associated with variations in estrogen levels, specifically high rates.</p>

<p>Cholesterol b-D-glucoside is a modified cholesterol that has been fluorinated and methylated. It is a complex carbohydrate that can be used in the synthesis of oligosaccharides and monosaccharides. Cholesterol b-D-glucoside is soluble in water, alcohols, and ethers and is insoluble in chloroform. The CAS number for Cholesterol b-D-glucoside 7073-61-2. This product is available for custom synthesis, which means it can be made to order with the specifications you need.</p>

<p>Digalactosyl diglyceride is a lipid that is found in the wax of plants. It has been shown to have anti-inflammatory properties and can be used as a nonsteroidal anti-inflammatory drug. Digalactosyl diglyceride binds to nuclear DNA and inhibits fatty acid synthesis, which leads to membrane destabilization.</p>

<p>Applications Useful substrate for the rapid colorimetric assay of N-Acetyl-beta-glucosaminidase in human urine.<br>References Muruhn, D.: Clin. Chim. Acta, 73, 453 (1976)<br></p>

<p>Applications Benzyl α-D-Mannopyranoside (cas# 15548-45-5) is a compound useful in organic synthesis.<br>References Rutschow, S., et al.: Bioorg., Med. Chem., 10, 4043 (2002), Duvet, S., et al.: Glycobiol., 14, 841 (2004),<br></p>

<p>Stability Hygroscopic<br>Applications 6-Deoxy-D-talose is an derivative of D-Talose (T005560), a monosaccharide sugar that can convert between aldose and ketose forms in pyridine in the presence of aluminum oxide.<br>References Davies, S.G., et al.: Org. Biomolec. Chem., 3, 348 (2005);<br></p>

<p>Applications Derivative of Neuraminic Acid<br>References Oetke, C., et al.: J. Biol. Chem., 277, 6688 (2002),<br></p>

<p>Applications Used in the synthesis of novel bis(D-mannose) compounds.<br>References Holman, G.D., et al.: Carbohydrate Res., 135, 337 (1985),<br></p>

<p>2,3,4-Tri-O-acetyl-a-D-arabinopyranosyl cyanide is a synthetic compound that is used to synthesize complex carbohydrates. This product can be customized for customers' needs and has high purity.</p>

<p>a-D-Fucose-1-phosphate is a complex carbohydrate. It is an Oligosaccharide with CAS No. that can be modified by methylation, glycosylation, or click modification. Carbohydrates are saccharides that can be modified by fluorination or synthesis. a-D-Fucose-1-phosphate has high purity and a custom synthesis can be ordered from the company.</p>