Monosaccharides

Methyl 6-O-tert-butyldimethylsilyl-2,3,4-tri-O-pivaloyl-a-D-mannopyranoside is a synthetic glycosylation agent that can be used for the synthesis of complex carbohydrates. This product has been fluorinated and saccharide modified. Methyl 6-O-tert-butyldimethylsilyl-2,3,4-tri-O-pivaloyl-aDmannopyranoside is available in CAS number: 5756782.

6-Deoxy-L-psicose is a d-arabinose analog that can be used as a substrate in the enzymatic synthesis of L-arabinose. It has been shown to inhibit the activity of phosphatase and glutamicum enzymes in vitro. 6-Deoxy-L-psicose binds to the active site of the enzyme through its phosphate group, which prevents access by an incoming substrate. The phosphate group also acts as an electron donor for the enzyme, stabilizing it through hydrogen bonding interactions. X-ray structures of 6-deoxy-L-psicose bound to corynebacterium glutamicum have revealed a ternary complex with two molecules of corynebacterium glutamicum and one molecule of 6-deoxy-L-psicose.

6-Chloro-6-deoxy-D-mannono-1,4-lactone is a saccharide that belongs to the group of polysaccharides. It can be custom synthesized and modified to meet your needs. 6CMDL is a synthetic carbohydrate product with high purity, which can be used in the synthesis of glycosylations or as a fluorinated mannose analogue.
6CMDL has been shown to have a methylation activity that can be used for the modification of carbohydrates or oligosaccharides.

Allosamizoline is a potent inhibitor of bacterial enzyme that is produced by the bacteria. It inhibits viral replication and has been shown to inhibit the biosynthesis of other bioactive molecules, such as cyclohexane ring, nitrogen atoms, and growth regulators. Allosamizoline is a bicyclic compound with an acetylation at the carbon atom and a cyclohexane ring. This compound also has two nitrogen atoms in its structure that are important for inhibiting bacterial enzymes. In addition, allosamizoline can be conjugated to fluorescein via an ester linkage. The fluorescein-allosamizoline conjugate can be used as a fluorescent probe for the detection of bacterial enzymes in live cells and tissues.

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The synthesis of 1,2-ethanediol is accomplished by the reaction of benzaldehyde with ethanol. This product is a synthetic sugar that is used in the modification of polysaccharides and glycosylation. The molecular weight of this product ranges from 200 to 400 Daltons. It has a CAS number of 730-25-6.

Lactonamycin is a linker that contains an oxygenated functional group. It can be found in some active natural products and has been synthesized in the laboratory. Lactonamycin is used as a model system for biosynthesis, where it was shown to efficiently produce glycosidic bonds when supplied with carbon sources such as glucose. The biological properties of Lactonamycin include its ability to inhibit microbial infection and inflammation, which may be due to its hydroxy group.

1,2,3,4-Tetra-O-benzyl-6-O-tert-butyldiphenylsilyl-a-D-mannopyranose is a synthetic glycoside that can be used as a building block for the synthesis of complex carbohydrates. It is a fluorinated sugar that can be modified with methyl groups and other functional groups. This product is available in high purity and can be custom synthesized to meet your specific needs.

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L-Threose is a sugar molecule that is used as a structural component of DNA and RNA. It is also an important part of the energy metabolism in cells. L-Threose can be enzymatically inactivated by glycosidases, which are enzymes that hydrolyze glycosidic bonds. The inhibition of glycosidases by L-threose may be useful for the prevention or treatment of diseases associated with enzyme activity, such as diabetes mellitus type II. L-Threose has been shown to have inhibitory properties against sephadex G-100, a membrane protein found in bacteria. L-Threose may be useful as a control agent for research into the response element of polymerase chain reaction (PCR).

Methyl 2-deoxy-b-D-ribopyranoside is a synthetic monosaccharide that has been modified by fluorination, monosaccharide, and methylation. It is an oligosaccharide that belongs to the group of complex carbohydrates. This compound can be used for glycosylation reactions or as a sugar donor in click chemistry. Methyl 2-deoxy-b-D-ribopyranoside has CAS No. 17676-20-9 and it's purity is greater than 99%.

L-Fucose is a monosaccharide that is an important component of glycoproteins and glycolipids. L-Fucose is also found in the cell wall of bacteria. The most abundant sources of L-fucose are from the hydrolysis of lactose or sucrose by bacteria, or as a result of intestinal microbial fermentation. L-Fucose has been shown to be involved in the regulation of many metabolic processes, including the glomerular filtration rate and sephadex g-100 binding capacity in the kidney. It has also been shown to improve growth in infant rats with protein malnutrition. The enzyme that catalyzes the conversion of D-arabinose to L-fucose is known as fucokinase.

5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-L-ribono-1,4-lactone is a high purity custom synthesis and custom synthesis of complex carbohydrates. 5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-L-ribono--1,4--lactone is a fluorination and an oligosaccharide that contains methylated sugar. It is a polysaccharide with a click modification that can be used for glycosylation and methylation. This product has been shown to be effective in the synthesis of oligosaccharides.

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D-erythrulose is a monosaccharide with the chemical structure of erythrose. It is structurally related to glycolaldehyde, which is a precursor in the biosynthesis of ribose. D-Erythrulose has been used for diagnosis and identification of various bacteria, such as C. glutamicum and Brucella species, by serological tests, as well as for the detection of gene products in E. coli K-12 cells. The determination of ATP levels in Brucella species has also been performed using magnetic resonance spectroscopy (MRS) after incubation with D-erythrulose.

Diethylstilbestrol (DES) is an endogenous substance that has been shown to be a potent estrogen. It is metabolized in the body to form stilbestrol glucuronide, which is excreted in the urine. Radiolabeling studies have shown that DES has a chemical structure similar to estradiol, although its pharmacologic effects are not as potent. Diethylstilbestrol glucuronide can be used for the diagnosis of cancer and other diseases by using nuclear medicine techniques such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Studies have also demonstrated that DES can induce erythropoietic protoporphyria in animals.

Sophoricoside is a natural compound present in the fructus of Sophora flavescens and is used as an anti-diabetic medicine. It has been shown to have genotoxic effects, which may be due to its ability to induce reactive oxygen species (ROS) and DNA damage. Sophoricoside also has a matrix effect on radiation. This effect has been shown in rat cardiac cells and human serum. Sophoricoside also exhibits hepatoprotective properties by reducing hepatic steatosis, which may be due to its ability to inhibit lipogenesis and stimulate fat oxidation. In addition, sophoricoside has been shown to have anti-inflammatory activities.

6-Deoxy-L-talose is a sugar that is found in the cell walls of bacteria. It is a component of glycan, which are long chains of sugar molecules linked together. Glycans are important for the structural integrity and function of bacterial cell walls. 6-Deoxy-L-talose is a monosaccharide that has been detected in the type strain of Bacillus subtilis and in wild-type strains of Pseudomonas aeruginosa. This sugar can be chemically analyzed using gas chromatography and mass spectrometry to determine its structure and chemical composition. 6-Deoxy-L-talose can be used to detect specific monoclonal antibodies against it, which could be useful for detecting bacterial infections or determining how antibiotics affect bacteria.

N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. It has been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).

Thiogalactose is a naturally occurring disaccharide that has been shown to have anti-inflammatory properties. It inhibits the production of inflammatory cytokines, such as tumor necrosis factor-α (TNF-α), and suppresses the growth of experimental colitis in mice. Thiogalactose also denatures fatty acids and prevents 3t3-l1 preadipocytes from undergoing cellular transformation. This compound also inhibits the uptake of bovine serum albumin by macrophages, which may be due to its alkylthio group. Thiogalactose has been shown to inhibit proliferation of cultured human cells, including monocytic leukemia cells, when used at concentrations less than 10 mM.

Ethyl b-D-galactopyranoside is a galactosylated glycoside that can be synthesized by the transfer of an acetyl group from ethyl alcohol to a sugar. It has antibacterial activity and is used in solvents as a stabilizer. The chemical structure of this compound consists of two benzene rings with an -OH group on one end, which are linked together by a covalent bond. The spacing between these two benzene rings is important for the stability of this compound, and it will break down when there is not enough space for the electron clouds to interact with each other. Ethyl b-D-galactopyranoside has been shown to be effective against tuberculosis bacteria, Mycobacterium tuberculosis, and Mycobacterium avium complex.

Glucosylceramide (Glc-Cer) is the common precursor in the biosynthesis of most glycosphingolipids, with exception of some Gal-Cer derivatives, such as, GM4. Glucosylceramide consists of a glucosyl moiety which is β-O-glycosydically linked to ceramide, which itself, consists of the long-chain aminoalcohol sphingosine and a fatty acid. Glucosylceramide (also called glucocerebroside) is synthesised enzymatically, by the glucosylceramide synthase-catalysed with the addition of a glucose residue to ceramide. Glucosylceramide is involved in the regulation of various cellular events and also serves as a main constituent in liposome formulations.

4,6-O-Benzylidene-D-glucose is a potent inhibitor of the enzyme dibutyltin oxide, which is involved in the synthesis of energy. It has been shown to have clinical activity in rat cardiomyocytes and has been tested in clinical studies. 4,6-O-Benzylidene-D-glucose inhibits enzymes by forming hydrogen bonds with their substrates. This compound also interacts with hydrochloric acid to form a stable complex that prevents it from interacting with other molecules. 4,6-O-Benzylidene-D-glucose is rapidly broken down into glucose and benzaldehyde when it reacts with carbonyl groups or amines. The asymmetric synthesis of this compound can be achieved using an intramolecular hydrogen transfer reaction.
4,6-O-Benzylidene glucose is derived from D-mannose derivatives and contains a hydroxyl group on the central carbon

Methyl b-D-mannopyranoside isopropylate is a high purity synthetic oligosaccharide. It has been custom synthesized and fluorinated with methyl groups on the sugar ring. It can be used for glycosylation, modification, and synthesis of saccharides. This product can also be used as a complex carbohydrate in the food industry.

L(+)-Ascorbic acid sodium salt is the L-isomer of ascorbic acid. It is an essential nutrient for humans and animals, and a cofactor for many enzymes involved in cellular metabolism. Ascorbic acid is an effective metal chelator, which can be used to treat infectious diseases such as tuberculosis. L(+)-Ascorbic acid sodium salt has been shown to have antioxidant properties. It also has antineoplastic activity against skin tumors when used at optimum concentration.

2-Deoxy-2-fluoro-D-galactose, also called 3-fluoro-6-hydroxymethyl-tetrahydro-pyran-2,4,5-triol, can be added to the medium of primary cultured rat hepatocytes to inhibit N-glycosylation of proteins. Immunoglobulin G (IgG) is the most common antibody found in blood and 2-deoxy-2-fluoro-D-galactose modifies the galactosylation of the N-linked glycan in the IgG-Fc receptor.  We also have this product from a non-animal origin, MD71984.

3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl fluoride is a synthetic glycoside that has been synthesized by the click modification of a fluorinated saccharide. The compound has an acetyl group at C3 and C6 positions with an OCH3 group at the C4 position. This compound has been used in glycosylation reactions to modify the carbohydrate moiety of peptides and proteins. It has also been used in research on complex carbohydrate chemistry.

D-Glucosamine 6-phosphate is a non-essential amino acid that belongs to the group of nucleotide sugar phosphates. It is a metabolite of the sugar D-glucose and it plays an important role in the energy metabolism of bacteria, plants, and animals. It has been shown to have anti-cancer effects on prostate cancer cells. D-Glucosamine 6-phosphate inhibits methyltransferase activity by binding to the enzyme's active site. This inhibition prevents DNA synthesis, leading to cell death. The structural analysis has been done using NMR spectroscopy on d-arabinose as a model substrate.

Short-term marker of glycemic control

Alpha-Chloralose (max. 20% beta-anomer) is a chemical compound primarily used as a sedative and for rodent control. It is synthesized through a chemical reaction involving glucose and chloral, creating a substance with unique physiological properties. Its mode of action primarily involves depressing the central nervous system, leading to reduced responsiveness and hypothermia in targeted organisms. Alpha-Chloralose induces symptoms that facilitate its application as a tranquilizer, particularly in small mammals and birds during scientific research. Additionally, due to its efficacy in lowering metabolic rates, it is utilized as a rodenticide. Within this context, it serves to humanely control rodent populations by inducing hypothermic conditions, leading to a humane death. Its dual functionality—both as a sedative and a rodenticide—makes it a versatile tool in scientific research and pest management. The specification of a maximum 20% beta-anomer content ensures a standardized formulation, enhancing its reliability and consistency for experimental and practical applications.

1,3,4,6-Tetra-O-acetyl-N-propanoyl-D-mannosamine is a sugar that is used for the synthesis of novel glycosides. It is prepared by the methylation of D-mannose with acetic anhydride in the presence of sodium methoxide. This reaction can also be carried out on a variety of other sugars and carbohydrates, such as D-galactose, D-xylose, or L-arabinose. 1,3,4,6-Tetra-O-acetyl-N-propanoyl-D-mannosamine has been shown to react with 4-(pyridinium)butanoic acid to produce 4-(pyridinium)butanal (1), which reacts with glycine to produce 1-(pyridinium)butanediamide (2). The carbonyl group in 2 can

3, 4-Dihydroxy-5-(hydroxymethyl)pyrrolidinone (3R,4R,5S) is a custom synthesis of a fluorinated compound that has been modified through methylation and monosaccharide substitution. This product has been designed for use in Click chemistry applications. The CAS number for this product is 100906-64-6.

Water-soluble, nontoxic, enzyme-resistant polymer for biological applications

Simvastatin acyl-b-D-glucuronide is a modification of simvastatin that has been synthesized and modified to provide high purity. It is a white, crystalline solid with a melting point of about 200°C. This compound can be used as an intermediate in the synthesis of oligosaccharides, polysaccharides, or other carbohydrate derivatives.

Quinovosamine hydrochloride (QNH) is a fatty acid that belongs to the group of galacturonic acid. It has been shown to be biologically active in wild-type strains and in some bacterial strains, including Pseudomonas aeruginosa. QNH has also been used for preparation of monoclonal antibodies directed against receptor activity, which are activated by QNH.

Xylose (Xyl) is an aldopentose also known as wood sugar (Collins, 2006). The main sources of xylose are hemicelluloses found in hardwood and perennial plants, such as, grasses, cereals, and herbs (Petzold-Welcke, 2014) and some algae. Xylose is used in the production of xylitol, a low calory sugar substitute. Xylose is used in glycosaminoglycan (GAG) biosynthesis, which is initiated by peptide O-xylosyltransferases, which transfer xylose onto selected serine residues in the core proteins. The first enzyme in the pathway, peptide O-xylosyltransferase, catalyzes the transfer of xylose from uridine diphosphate (UDP)-α-D-xylose onto serine and thus determines the site(s) of GAG attachment on the core protein (Briggs, 2018).

2-O-b-D-glucopyranosylcucurbitacin E is a natural product that has been isolated from the roots of Cucurbita maxima. This compound has been shown to have bioactive properties, including antioxidant and antimicrobial activity. The extract was tested on chronic cough patients with type 2 diabetes mellitus. The treatment group showed significant improvements in symptoms and bioactive phytochemical levels compared to the control group.
2-O-b-D-glucopyranosylcucurbitacin E is a white powder that is soluble in methanol and water but not in chloroform or ether. It can be analyzed by liquid chromatography, which separates the different components of a sample by passing it through a column filled with an adsorbent material that retains some components more than others.

Used in synthetic organic chemistry and natural product synthesis. Induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. It is used for synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.

α-D-Mannose-1-phosphate sodium is a synthetically made mannose phosphate. This compound is used in the synthesis of oligosaccharides and glycoproteins.

a-Acetobromo-D-xylose is an oligosaccharide sugar used in glycosylation and polysaccharide modifications. It is synthesized by the fluorination of xylose with acetic acid, bromine, and a base. The product is purified by vacuum distillation and recrystallization. In addition to its use as a carbohydrate, this product can be modified using methylation or click chemistry to create derivatives.

L-Glucono-1,4-lactone is a substance that belongs to the group of compounds known as alpha hydroxy acids. It is produced in the body by an enzyme called l-gluconolactonase and is present in small quantities in many fruits and vegetables. L-Glucono-1,4-lactone has been shown to prevent skin aging and protect against UV light damage through its antioxidant properties. This compound can be found in sunscreens or it can be taken orally to provide protection from the sun. Clinical data on L-Glucono-1,4-lactone treatments are not yet available.

2-Deoxy-D-galactose is a metabolite of the carbohydrate galactose. It is found in the rat striatum and has been shown to inhibit glutamate dehydrogenase activity. 2-Deoxy-D-galactose also inhibits 2,3,4,5 tetrahydropyridine (MPTP) induced neurotoxicity in mice by increasing levels of uridine and nucleotides in the brain. This agent also has an effect on glomerular filtration rate and on protein synthesis. The glycoside derivatives of 2-deoxy-D-galactose are formed by joining a sugar molecule to hydroxyl group. These derivatives are then transported into cells via glucose transport proteins.

L-iduronic acid (IdoA) (Collins, 2006) is the major uronic acid component of the glycosaminoglycans dermatan sulfate, chondroitin sulfate and heparin. Iduronic acid is also present in heparan sulfate, although in a minor amount relative to glucuronic acid. Glycosaminoglycans represent a physiologically important group of molecules involved in a variety of biological functions, such as, cell proliferation, cell-to-cell communication, wound healing, coagulation, morphogenesis, and pathogenesis. Glycosaminoglycans present an intriguing target for the design of new approaches for diagnostic and therapeutic agents against various infectious diseases (Kamhi, 2013).

The polysaccharide Lentinan is isolated from the mushroom L. edodes (shitake mushroom). The primary structure is a β-(1–3)-glucose backbone with two (1–6)-β-glucose branches for each five glucose resiodues. Lentinan is clinically used for cancer treatment both in China and Japan. According to the clinical studies published in and outside of China, lentinan-based drugs are used for the treatment of various cancers, including lung, gastric, colorectal and other cancers. In addition, lentinan-based drugs are also used for treating HIV, hepatitis and malignant pleural effusion.

D-Xylonic acid-1,4-lactone is a substrate that participates in the synthesis of glyceric acid. It has been shown to be a synthetic substrate for benzyl groups and leukemia HL-60 cells. D-Xylonic acid-1,4-lactone can react with chloride ions to form D-xylose. The product of this reaction is an epimerization reaction that occurs when the hydroxyl group on the carbon atom adjacent to the carbonyl group (C1) reacts with a proton from water to form a double bond at C2. This conversion produces xylonic acid and lactone.

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Used in synthetic organic chemistry and natural product synthesis. Induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. It is used for synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.