APIs pour la recherche et les impuretés

<p>Procyanidin B2 3,3'-di-o-gallate (PB2DOG) is a gallotannin that can be found in the leaves of the dogwood tree. It has dose-dependent effects on the serine protease activity of butanol, which is used as a model for pancreatic lipase. PB2DOG also inhibits the activity of viruses such as hepatitis C and herpes simplex virus type 1, and cancer cells such as du145 and japonica. PB2DOG has been shown to induce apoptosis in cancer cells by reducing DNA synthesis and inhibiting protein synthesis. The mechanism behind this effect is not fully understood, but it may be related to its ability to inhibit cCAAT/enhancer binding protein (C/EBP), an important transcription factor for cell proliferation.</p>

<p>DL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.</p>

<p>Ethylenediamine p-toluenesulfonate is an inhibitor of various kinases that have been implicated in cancer cell replication and tumor growth. This chemical compound has been shown to induce apoptosis, or programmed cell death, in human cancer cells. Ethylenediamine p-toluenesulfonate has also been studied as a potential treatment for methotrexate-induced nephrotoxicity, a common side effect of chemotherapy. Additionally, it has been identified as a potent analog of astaxanthin, which is a naturally occurring carotenoid with antioxidant properties. The use of ethylenediamine p-toluenesulfonate as a kinase inhibitor may hold promise for the development of novel cancer therapies.</p>

<p>Fluorobexarotene is a fatty acid that has been shown to induce the expression of inflammatory genes in animal models. It has also been shown to inhibit the growth of human cancer cells in vitro and in vivo. Fluorobexarotene is used for the diagnosis of x-linked adrenoleukodystrophy and is currently being studied as a treatment for liver cancer. This molecule is also an agonist of retinoic acid receptors, which may be responsible for its effects on gene transcription.</p>

<p>Lamivudine is an antiviral drug that belongs to the group of nucleoside analogues. It can be used as a single agent or in combination with other antiviral drugs for the treatment of HIV infection. Lamivudine is a prodrug that is converted to its active form, which inhibits viral DNA synthesis by competing with natural substrates for incorporation into viral DNA by inhibiting viral polymerase activity and causing chain termination. The long-term toxicity of lamivudine has been studied in animals and humans. Although it does not cause any serious side effects, it can cause hepatitis and reactivation of hepatitis B virus (HBV). Lamivudine has been shown to inhibit the IL-2 receptor on T cells, which may contribute to its beneficial effect on HBV.</p>

<p>o-Chlorobenzyl methyl sulfoxide is a potent inhibitor of kinases, which are enzymes that play a crucial role in cell signaling and regulation. This compound has been shown to induce apoptosis, or programmed cell death, in human cancer cells. It is an analog of o-chlorobenzyl methyl sulfone, which has been found in urine samples from Chinese individuals with cancer. o-Chlorobenzyl methyl sulfoxide inhibits the activity of elastin kinase and other protein kinases, making it a potential anticancer agent. Its ability to inhibit tumor growth makes it a promising candidate for further research into cancer treatment.</p>

<p>1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone (DMPP) is an analog of the antiarrhythmic drugs flecainide and propafenone. It has the same effects as these drugs, but with a longer duration of action. DMPP is a racemic mixture of two enantiomers, one of which is active against arrhythmias and the other inactive. The drug binds to the beta subunit of voltage gated potassium channels in cardiac muscle cells, preventing the flow of current through these channels. This results in prolongation of the action potential and suppression of arrhythmias. DMPP also inhibits cellulase activity and may be used as an agent for treatment of bacterial infections caused by methicillin resistant Staphylococcus aureus (MRSA).</p>

<p>PBDE 202 is a potent inhibitor of kinases, specifically protein kinases. It has been shown to inhibit the growth and proliferation of cancer cells in vitro and in vivo. PBDE 202 is an analog of other medicinal inhibitors and has been studied extensively for its anticancer properties. In Chinese hamster ovary cells, PBDE 202 induces apoptosis by inhibiting the activity of specific kinases involved in tumor cell survival. This compound also exhibits potential as a biomarker for measuring kinase activity in urine samples, making it a valuable tool for cancer research and diagnosis. Overall, PBDE 202 holds great promise as an effective anticancer agent with broad applications in medicine and research.</p>

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<p>Benzylpenicillin diethylaminoethyl ester hydroiodide is a potent broad-spectrum antimicrobial agent that inhibits the growth of bacteria by inhibiting protein synthesis. It is used to treat microbial infections and has been shown to be effective against Streptococcus species, including Streptococcus pneumoniae, Streptococcus pyogenes, and Streptococcus viridans. Benzylpenicillin diethylaminoethyl ester hydroiodide binds to the 50S ribosome subunit of bacteria and prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis. This binding prevents protein synthesis and cell division.</p>

<p>Pioglitazone Pyridine-6-[4-[2-[5-ethyl-6-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]propionamido]-1,3,4-thiadiazol-2(3H)-ylidene]aminocarbonyl]-1,3,4-thiadiazole is a drug that belongs to the group of thiazolidinediones. It is an oral hypoglycemic agent that lowers blood sugar by stimulating insulin release from the pancreas and increasing peripheral tissue sensitivity to insulin. Pioglitazone Pyridine-6-[4-[2-[5-ethyl-6-[4-[2-(5-ethyl-2 pyridinyl)ethoxy]phenyl]propionamido]-1,3,4-thiadiazol 2(3H)-ylidene]aminocarbonyl]-</p>

<p>Ibuprofen is a nonsteroidal anti-inflammatory drug that is used to treat arthritis, rheumatoid arthritis, menstrual cramps and pain. Ibuprofen is a racemic mixture of two enantiomers, ibuprofen and S (+) -ibuprofen. The dextran sulfate method is an analytical method used to determine the concentration of ibuprofen in biological fluids such as human serum or urine. This test can be done by first treating the sample with trifluoroacetic acid (TFA) to convert ibuprofen to its glucuronide conjugate. The glucuronide conjugates are then deproteinized with hydrochloric acid, which converts them into their corresponding carboxylated derivatives. This conversion allows for the separation of ibuprofen from interfering substances using preparative hplc and quantification using mass spectrometry. Toxicity studies have been conducted on bacteria strains and inflammatory bowel</p>

<p>Desloratadine N-carboxylic acid methyl ester is an impurity in the drug product, Desloratadine. The chemical name for this impurity is desloratadine N-carboxylic acid methyl ester. This product can be found in the Metabolism studies section of our catalog under natural products. Desloratadine N-carboxylic acid methyl ester is a custom synthesis with a purity level of 99%. It is used as an analytical standard and has been shown to have similar retention times as the CAS No. 165740-03-4 reference standard.</p>

Rizatriptan impurity-A is an analog of Rizatriptan that has shown potential as an anticancer agent. It has been found in urine and has been studied for its ability to induce apoptosis in human cancer cells. This compound is a kinase inhibitor, which means it can inhibit the activity of specific proteins involved in cell replication and growth. As a result, it may be useful as a medicinal inhibitor for the treatment of various tumors and cancers. The research on Rizatriptan impurity-A is ongoing, but it shows promise as a potential new therapy for cancer patients.

<p>7-Aminopyrazolo[1,5-a]pyrimidine-3,6-dicarboxylic acid 3,6-diethyl ester is an impurity in the synthesis of drugs. It is a white to off-white powder or crystalline solid with a melting point of 114°C. 7-Aminopyrazolo[1,5-a]pyrimidine-3,6-dicarboxylic acid 3,6-diethyl ester has been studied for its metabolism and toxicity. It is not naturally occurring and was synthesized in the laboratory. It may be used as a reference material for pharmacopoeia standards.</p>

<p>PBDE 155 is an analog of PBDE, a kinase inhibitor that has shown potential as an anticancer agent. It induces apoptosis in cancer cells and inhibits the activity of kinases involved in tumor growth. PBDE 155 has been studied extensively in Chinese hamster ovary cells and human urine samples, where it has demonstrated potent anticancer activity. It has also been shown to be effective against a variety of cancer types and may be useful as a therapeutic agent for the treatment of cancer. Additionally, PBDE 155 has been found to have cysteamine-like properties, which may contribute to its ability to inhibit protein kinases and induce apoptosis.</p>

<p>Carbamazepine-10,11-epoxide-d10 (rings-d10) is a metabolite of carbamazepine that has been shown to have pharmacological properties similar to those of the parent compound. It is used in drug development, metabolism studies, and as an impurity standard for pharmaceutical products. Carbamazepine-10,11-epoxide-d10 (rings-d10) is not found in nature and can be synthesized from carbamazepine. This metabolite has a purity of at least 98% and may be used as an analytical standard or as a research and development compound for pharmacopoeia.</p>

<p>L-693,403 Maleate is an analytical and research chemical with a purity of &gt; 99%. L-693,403 Maleate is used as an impurity standard for HPLC analysis and drug development. It can also be used as a reference standard in the production of APIs. L-693,403 Maleate is an impurity in the synthesis of several drugs, including clozapine, fluoxetine, and loratadine. The natural form of L-693,403 Maleate can be found in the leaves of the plant Acacia holosericea. Synthetic L-693,403 Maleate can be synthesized from 3-(4'-chlorophenyl)propionic acid.</p>

<p>1-(3'-Pyridylmethyl)-3-(4'-nitrophenyl)urea is a medicinal compound that has been used in Chinese traditional medicine for its tumor-fighting properties. It acts as a potent inhibitor of protein kinases, which are enzymes involved in cell signaling and proliferation. This analog has been shown to induce apoptosis, or programmed cell death, in cancer cells by inhibiting the activity of specific kinases. The compound has also demonstrated anticancer activity in human cancer cell lines and may have potential as a therapeutic agent for the treatment of various types of cancer. Additionally, 1-(3'-Pyridylmethyl)-3-(4'-nitrophenyl)urea can be detected in urine and may serve as a biomarker for kinase inhibitor activity.</p>

<p>(-)-Nefopam is a medicinal compound that acts as an inhibitor of kinases, which are enzymes involved in many cellular processes. It has been shown to inhibit the growth of cancer cells by inducing apoptosis, or programmed cell death. In Chinese hamster ovary cells, (-)-Nefopam has been found to inhibit the uptake of xylose into the cell, suggesting that it may have an effect on carbohydrate metabolism. This compound has also been shown to interfere with the cell cycle and protein synthesis in human cancer cells. Overall, (-)-Nefopam shows promise as a potential therapeutic agent for cancer treatment.</p>

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<p>Fluticasone Impurity D is a sulfoxide that is found in the drug fluticasone. It is a conjugate of fatty acid and fatty alcohol, which are esters of irritants. Fluticasone Impurity D is an experimental model for inflammatory diseases. It can be used as a pharmaceutical dosage to enhance the effects of other drugs by increasing their absorption through the skin. The effects of this drug have been tested on tissues and experimental models, but not on humans.</p>

<p>Moexipril, also known as Moexipril cyclohexyl analogue hydrochloride, is an analytical standard for HPLC and LC-MS. It is a white to off-white powder with a molecular weight of 461.84. Moexipril is soluble in ethanol and methanol, but insoluble in water. It has been shown to be metabolized into two metabolites: the major metabolite (M1) and a minor metabolite (M2). The CAS number for Moexipril is 1356019-89-0.</p>

<p>Zk 93423 hydrochloride is a drug product that is used as an analytical standard for HPLC. It belongs to the class of natural products and has been shown to be effective against gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). Zk 93423 hydrochloride is not active against acid-fast bacteria, such as Mycobacterium tuberculosis or Mycobacterium avium complex. Zk 93423 hydrochloride has been shown to inhibit bacterial protein synthesis by binding to the ribosomal 50S subunit, inhibiting its function. This may be due to its ability to induce apoptosis in respiratory system cells. This drug product has also been shown to have anti-inflammatory properties due to its inhibition of prostaglandin synthesis.</p>

<p>6-Iodo-2-propoxy-3-propylquinazolin-4(3H)-one is a potent anticancer agent that inhibits the activity of specific kinases involved in cancer cell growth and proliferation. It has been shown to induce apoptosis, or programmed cell death, in cancer cells by blocking the activity of certain proteins. This compound is structurally similar to other kinase inhibitors used in medicinal chemistry, such as gefitinib and erlotinib. 6-Iodo-2-propoxy-3-propylquinazolin-4(3H)-one has been tested on human and Chinese hamster ovarian cells and has demonstrated significant antitumor activity. It is a promising candidate for the development of new cancer therapies due to its potent inhibitory effects on kinases involved in tumor growth and progression. Additionally, this chemical analog can be detected in urine samples, making it a useful tool for studying kinase activities in vivo.</p>

<p>NRX-252262 is an inhibitor that has shown potent anticancer activity in various types of cancer cells. It is a Chinese hamster ovary cell-derived analog of indirubin, which is a natural compound found in human urine and glycerol. NRX-252262 inhibits kinases, which are enzymes that play a role in cell division and proliferation. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. NRX-252262 has been shown to be effective against multiple types of cancer, making it a promising candidate for cancer treatment. Its potent anticancer activity makes it one of the most sought-after inhibitors for cancer research and development of new treatments.</p>

<p>2,12-Dihydro-1,3-dimethyl-8-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a metabolite of the drug 2-[2-(4,5,-dihydroimidazo[1,2a]imidazol -2(3H)-yl)ethoxy]-N-(methylsulfonyl)benzamide. It can be used as an impurity standard for the manufacture of drugs and as a research chemical.</p>

<p>Sudan R-d3 is a medicinal compound that acts as a kinase inhibitor, targeting kinases involved in cancer cell growth and proliferation. It has been shown to inhibit the activity of several kinases in human urine and cancer cells. Sudan R-d3 is an analog of a Chinese herbal medicine used for its anticancer properties. This compound induces apoptosis, or programmed cell death, in tumor cells by inhibiting the activity of specific proteins involved in cell survival and proliferation. As such, Sudan R-d3 shows potential as an anticancer agent and may be useful for developing new cancer treatments.</p>

<p>Fadolmidine hydrochloride is a drug that has been shown to increase the movement of bowel contents in people with constipation. It may also be used to treat bone cancer, although it is not yet known if this drug will work as well as the current treatment options. Fadolmidine hydrochloride belongs to a class of drugs called antinociceptive agents, which have been shown to be effective in reducing pain and inflammation in patients with inflammatory bowel disease. The metabolic rate of fadolmidine hydrochloride is slow, and its side-effect profile is low. Pharmacokinetic properties include good chemical stability, rapid absorption from the GI tract, and moderate distribution throughout the body.</p>

<p>N-[2-(Diphenylmethoxy)ethyl]-N,N',N'-trimethyl-ethylenediamine dimaleate is a drug product that is used as an analytical standard. It is a synthetic compound that has been shown to have anti-inflammatory properties. This product is also metabolized in the liver, and can be used to study the metabolism of drugs. CAS No. 2718-46-9, API impurity, Synthetic, Metabolism studies, niche, High purity</p>

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Acetamido-5-benzylthio-1,3,4-thiadiazole is an impurity that is found in the drug product acetamido-5-(2,6-dichlorobenzyl)thio-1,3,4-thiadiazole. It has been used as an analytical standard for HPLC and as a pharmacopoeia impurity standard. Acetamido-5-benzylthio-1,3,4-thiadiazole is also a metabolite of acetamido-5-(2,6 dichlorobenzyl)thio-1,3,4 thiadiazole. This compound has been detected in natural sources such as plants and animals. Acetamido-5-(2,6 dichlorobenzyl)thio 1,3,4 thiadiazole can be synthesized by reacting 2 chloroacet

<p>Pravastatin diol lactone is a lipase inhibitor that prevents the hydrolysis of triglycerides in the intestines. It also inhibits the synthesis of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Pravastatin diol lactone has been shown to be effective in reducing serum cholesterol levels in animal models and inhibiting esterification of cholesterol by preventing the conversion of HMG-CoA to mevalonic acid, which is an important step in the synthesis of cholesterol. Pravastatin diol lactone is a polyketide that was discovered from a fungus and chemically altered to produce this drug.</p>

<p>Ornidazole-hydroxy is a drug product that is manufactured using HPLC. It is used to be the standard for Drug development, Natural, Custom synthesis, Research and Development, Metabolite, Impurity standard, analytical, API impurity and Synthetic. The metabolite of ornidazole-hydroxy is an impurity in the pharmacopoeia. Ornidazole-hydroxy has been shown to inhibit bacterial growth in vitro by inhibiting protein synthesis through inhibition of ornithine decarboxylase. Ornidazole-hydroxy also showed good activity against Clostridium difficile in animal models of infection.</p>

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<p>25-Hydroxyvitamin D2 3-hemisuccinate is a drug product that belongs to the group of natural products. It is a metabolite of vitamin D2 and has been shown to have anti-inflammatory properties. 25-Hydroxyvitamin D2 3-hemisuccinate is used as an analytical standard for HPLC, but it is also used in research and development for drug development. This product can be used as an impurity standard for API's because it is easily purified and stable in storage. Research has shown that this compound may be effective in protecting against osteoporosis, cardiovascular disease, and cancer.</p>

<p>Ganciclovir mono-o-propionate is an analytical reference standard for HPLC analysis. It is also a drug development intermediate, an API impurity, and a metabolite of ganciclovir. Ganciclovir mono-o-propionate is a crystalline solid with a melting point of 119°C and a molecular weight of 312.5. This compound can be found in the USP/NF (2009) as an impurity in the ganciclovir product. Ganciclovir mono-o-propionate has been used by companies to synthesize ganciclovir or other analogues for research purposes. The natural form of this compound can be found in plants such as apple leaves and grape leaves, but it can also be synthesized from chloroacetic acid and propionic acid.</p>

<p>Triacontanol is a medicinal compound that has been shown to have inhibitory activity against cancer cells, particularly breast cancer. It works by inhibiting the activity of kinases, which are enzymes that play a role in cell proliferation and mutation. Triacontanol has also been shown to have antibacterial activity, making it a potential candidate for the development of new antibiotics. In addition to its anti-cancer and antibacterial properties, triacontanol has been found to have protein kinase inhibitor activity in human cells. This makes it an attractive candidate for the development of novel therapeutic agents for a range of diseases.</p>

<p>Albendazole is an anti-helminthic drug that is structurally classified as a benzimidazole. It has been shown to be effective against a variety of helminths, including roundworms, pinworms, hookworms, and tapeworms. Albendazole impurity F is an analytical standard for the determination of albendazole in pharmaceutical products by HPLC. It also serves as a reference substance to establish the purity of drug products containing albendazole and its metabolites. Albendazole impurity F is not considered to be a metabolite of albendazole because it has been shown to be stable under acidic conditions and can be synthesized from other starting materials.</p>

<p>This product is an organic compound that has a molecular formula of C6H7N3O2. It is a white solid with a melting point of 76.5 °C and an elution time of 7 minutes (range, 1-10 minutes). The detection method is based on the color change from yellow to blue in the presence of dimethylformamide (DMF). This product is used as a solvent for various chemical reactions and can be used in the synthesis of other products. 3-(Formylamino)-1H-pyrazole-4-carboxamide is used in analytical chemistry to determine substances such as pH, ionic strength, and concentration. In addition, this product can be used to quantify substances such as drugs or pharmaceuticals.</p>

<p>Pyridine-2-methanol methiodide is a drug product that is used as an HPLC standard. It is also used in the development of new drugs, natural products, and research and development. Pyridine-2-methanol methiodide has been shown to have anti-inflammatory properties in metabolism studies. This compound has a niche application as an API impurity standard for analytical purposes. The CAS number for this compound is 3313-51-7. Synthetic methods are required to produce this substance. It is a high purity chemical with pharmacopoeia applications.</p>

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<p>Bazedoxifene 5-β-D-glucuronide is an analog of bazedoxifene, a selective estrogen receptor modulator used in the treatment of osteoporosis. This compound has shown promising anticancer properties and has been studied extensively in Chinese hamster ovary cells. Bazedoxifene 5-β-D-glucuronide has been found to induce apoptosis in cancer cells and inhibit the activity of kinases involved in tumor growth. It is a potent inhibitor of several human protein kinases, including cyclin-dependent kinase 2 (CDK2) and glycogen synthase kinase 3 beta (GSK3β), which are important targets for medicinal chemists developing kinase inhibitors. This compound is excreted primarily in urine and may have potential as a therapeutic agent for various types of cancer.</p>

<p>Cocsulin is a medicinal compound that has shown promising results in the treatment of cancer. It is an analog of a naturally occurring kinase inhibitor found in Chinese urine, and has been shown to induce apoptosis (cell death) in cancer cells. Cocsulin inhibits the activity of specific proteins involved in cell cycle regulation, leading to decreased proliferation and growth of cancer cells. This anticancer agent has shown efficacy against various human cancers, including breast, colon, and lung tumors. Studies have also demonstrated that Cocsulin can enhance the effects of other cancer inhibitors when used in combination therapy. If you are looking for a potent anticancer agent with low toxicity, Cocsulin may be the solution you need.</p>

<p>Desdifluoromethoxy hydroxy pantoprazole is a synthetic compound that is used as an impurity standard for the drug product Pantoprazole. It has a purity of ≥98% and is stable under ambient conditions. Desdifluoromethoxy hydroxy pantoprazole is not active on its own, but it is a metabolite of pantoprazole. It can be used to study the metabolism of pantoprazole.</p>

3'-Deoxy-3'-chlorothymidine is an antiviral compound that is synthesized by the on-line coupling of 2,4-dichlorobenzoyl chloride with 3,4-dideoxycytidine. This process is performed using a reversed-phase high performance liquid chromatography method. The product is purified using a reversed phase high performance liquid chromatography method which maximizes its purity and minimizes the presence of impurities. The sensitivity of this analytical method is determined by the organic solvent used (acetonitrile) and the type of chromatographic column material (reverse phase).

<p>Lincomycin impurity B is a chemical substance which is the result of the metabolism of lincomycin. It is found in the urine and feces of patients who have taken lincomycin orally. Lincomycin impurity B has been detected in various commercial formulations of lincomycin, but its concentration varies with different batches. The HPLC standard purity for lincomycin impurity B is up to 99%. Lincomycin impurity B can be used as an analytical standard for HPLC analysis and as an API impurity in drug development. It also may be used as a research metabolite or pharmacopoeia reference material.</p>

<p>3-Hydroxy deoxy dihydro artemisinin is a drug product that is an analytical standard for the determination of artemisinin in natural and synthetic samples. It is a metabolite of artemisinin, which is a natural compound extracted from Artemisia annua L. (Asteraceae). 3-Hydroxy deoxy dihydro artemisinin is also an impurity found in commercial preparations of artemisinins. 3-Hydroxy deoxy dihydroartemisinin has been used as an API impurity standard, and has been synthesized as part of drug development research and development. The purity of this substance was determined by HPLC analysis, and it complies with the pharmacopoeia requirements.</p>

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<p>Rhubofix is a medicinal product that contains xylose, a natural sugar found in human urine and protein. It has been shown to be an inhibitor of tumor kinases, which are enzymes involved in the growth and proliferation of cancer cells. Rhubofix has been found to induce apoptosis, or programmed cell death, in cancer cells, making it a potential treatment for various types of cancer. This product also acts as an inhibitor of the cell cycle, preventing cancer cells from dividing and multiplying. Rhubofix has been used traditionally in Chinese medicine as an inhibitor of kinase activity and has shown promising results in preclinical studies as a potential anti-cancer agent.</p>

<p>2,3,6,7-Tetrachlorobiphenylene is a potent inhibitor of kinases that are involved in cancer cell growth and proliferation. It is an analog of tolvaptan, a drug used to treat hyponatremia by increasing urine output. This compound has been shown to induce apoptosis in cancer cells and inhibit tumor growth. Studies have found that 2,3,6,7-Tetrachlorobiphenylene inhibits the activity of human protein kinases and may be effective against various types of cancer. This Chinese compound has promising anticancer properties and could potentially be used as a therapeutic agent for cancer treatment.</p>

<p>Regaloside H is a medicinal compound found in urine that has shown promising results in the treatment of cancer. It works by inducing apoptosis, or programmed cell death, in cancer cells. Regaloside H has been shown to inhibit kinase activity, which is involved in cell cycle regulation and proliferation. This inhibitor effect makes it a potential candidate for anticancer therapy. In Chinese medicine, Regaloside H has been used as an herbal remedy for treating tumors. Studies have shown that it can target specific kinases that are overexpressed in certain types of human cancers, making it a potentially effective treatment option for cancer patients. Overall, Regaloside H represents a promising new avenue for the development of novel anticancer therapies.</p>

<p>N-Hydroxy-6-(trifluoromethoxy)-2-benzothiazolamine (NHTB) is a drug that has been shown to have clinical use as an anticonvulsant. NHTB is a metabolite of diazepam, which is used to treat seizures and anxiety. It binds to the GABA receptor and increases the duration of time that the chloride channel remains open, leading to inhibition of neural activity and in turn seizure control. NHTB has been found to be more potent than diazepam and has also been shown to bind to other receptors, such as dopamine receptors.</p>

<p>2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid 2-(carboxymethoxy)-2-oxoethyl ester is a drug product that belongs to the class of Custom synthesis. It is a metabolite of loratadine, an antihistamine drug. The compound is a metabolite of loratadine, which is an antihistamine drug used for the treatment of allergies. It is produced by the oxidation of loratadine by cytochrome P450 enzymes and can be detected in urine at concentrations up to 5 ng/mL. 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid 2-(carboxymethoxy)-2-oxoethyl ester has been shown to be effective in inhibiting the growth of bacteria that are resistant to penicillin and erythromycin.</p>

<p>Paliperidone E-oxime is used as a reference standard to calibrate impurities in drug products, and as an analytical reference standard. Paliperidone E-oxime is also used in the synthesis of other drugs. Paliperidone E-oxime has a CAS number of 1388021-46-2 and a molecular weight of 395.37 g/mol.</p>

<p>5-Eicosene is an analog that has been shown to have potent anticancer properties. It acts as an inhibitor of various protein kinases, including cyclin-dependent kinases, which are essential for cancer cell growth and division. Studies have demonstrated that 5-Eicosene induces apoptosis in Chinese hamster ovary cells and human cancer cells, suggesting its potential as an effective anticancer agent. Additionally, this compound inhibits the activity of certain urinary protein kinases, which may be valuable in the diagnosis and treatment of cancer. Overall, 5-Eicosene shows promise as a potent inhibitor with therapeutic potential against various types of cancer.</p>

<p>Enrofloxacin impurity E is a product of the synthesis of enrofloxacin, with high purity and analytical standards. It is synthesized from natural products, and it can be used as an impurity standard for HPLC analysis. Enrofloxacin impurity E also has pharmacopoeia and CAS number 1369495-59-9. This substance is used in drug development and research to study metabolism.</p>

<p>K-(D-1-Nal)-fwll-NH2 is a drug product that is custom synthesized to order. It has been shown to have high purity, analytical and metabolic studies. The metabolite of K-(D-1-Nal)-fwll-NH2 is D-1-nal. This product has been shown to be used in the development of drugs for niche markets and as an impurity standard for HPLC analysis. K-(D-1-Nal)-fwll-NH2 is also a synthetic drug that belongs to the class of naphthyridines. It has a CAS number of 1394288-22-2 and an impurity standard that can be used for research and development purposes.</p>

<p>R401553 is a potent protein kinase inhibitor that has been shown to induce apoptosis and arrest the cell cycle in various human cancer cell lines. It belongs to the class of indole derivatives and has been found to be particularly effective against leukemia and tumor cells. R401553 selectively inhibits kinases that are involved in cell proliferation, survival, and angiogenesis. This inhibitor has been tested on Chinese hamster ovary (CHO) cells and human cancer cell lines, showing promising results in inhibiting tumor growth. R401553 may have potential as a therapeutic agent for the treatment of various cancers.</p>

<p>Please enquire for more information about 1-[2,3,4-Tris(methoxymethoxy)phenyl]-ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit</p>

Tetramethylrhodamine cadaverine is a medicinal compound that has shown promising results in the treatment of cancer. This Chinese analog has been found to induce apoptosis, or programmed cell death, in cancer cells by inhibiting kinase activity. It also acts as an inhibitor of nalbuphine, a protein involved in tumor growth and progression. Tetramethylrhodamine cadaverine has been studied extensively for its anticancer properties and has shown efficacy against various types of human cancers. Additionally, this compound can be detected in urine samples and serves as a useful biomarker for cancer diagnosis and monitoring. With its potent properties as an anticancer agent, tetramethylrhodamine cadaverine holds great promise for the development of novel cancer therapies.

<p>Amlodipine besilate impurity A is a low-energy impurity that is formed in the crystallization process. It is an amide compound that has a hydrogen bond with crotonic acid and amlodipine, and can be found in acidic environments. The structural formula for this impurity is C8H14NO2S·C4H6O4·CH3OH.</p>

<p>GPI-16552 is an inhibitor that has shown potential as an anticancer agent. It induces apoptosis in cancer cells by disrupting the cell cycle and inhibiting the activity of certain proteins. Studies have shown that GPI-16552 can inhibit tumor growth in human cancer cell lines, making it a promising candidate for future cancer treatments. Additionally, this inhibitor has been found in Chinese urine samples and may have potential as a natural source of vitamin-like compounds. Overall, GPI-16552 is a powerful inhibitor with exciting potential for both cancer research and health supplementation.</p>

<p>Mono-(4-methyl-7-oxooctyl)phthalate (MMP) is a metabolite of the phthalate esters, which are synthetic chemicals used in plastics and other materials. MMP has been detected in the urine of neonates and preschool children, suggesting that it can be absorbed through skin contact. This compound is also found in wastewater, where it may cause estrogenic effects on human cells. The reaction solution of MMP with insulin-like growth factor (IGF) was studied by kinetic analysis and logistic regression to determine its binding affinity for IGF binding proteins. MMP has shown to be biodegradable under aerobic conditions.</p>

<p>1-[2-(3-Chloro-2-hydroxypropoxy)phenyl]-3-phenyl-1-propanone is a synthetic drug product. It is an impurity standard for HPLC, and drug development and research. This compound is also used as an analytical reference. The CAS number for this chemical is 165279-79-8.</p>

<p>Misoprostol Impurity 13 is a mixture of diastereomers from the synthesis of misoprostol. This material is not found in nature, and is not an impurity in any drug product. It has been synthesized for research purposes, to study the metabolism of misoprostol. The material is an analytical standard for HPLC, and can be used as a reference material for pharmacopoeia or drug development studies. Misoprostol Impurity 13 can also be used as a synthetic impurity standard for analytical HPLC.</p>

<p>Irinotecan is a drug product that is used in the treatment of cancer. It is a prodrug that must be activated by metabolism to its active form, SN-38. Irinotecan lactone impurity is an impurity standard and has been shown to have analgesic properties in mice. It has also been shown to inhibit the growth of colon cancer cells.</p>

<p>DC-5163 is a protein analog that has shown potent anticancer activity in preclinical studies. It inhibits the activity of kinases, which are enzymes involved in cancer cell growth and survival. DC-5163 has been shown to induce apoptosis, or programmed cell death, in various types of cancer cells, including those from human tumors and Chinese hamster ovary cells. This compound also acts as a toxin for cancer cells by interfering with their ability to divide and grow. In addition, DC-5163 has shown promising results as an inhibitor of tumor growth in animal models. Its potential as a therapeutic agent for cancer treatment is currently being investigated.</p>

<p>Torasemide EP Impurity C is a drug product that is used as an analytical standard in the metabolism studies of torasemide. Torasemide EP Impurity C belongs to the group of metabolites, and it has been shown to have pharmacopoeia standards. Torasemide EP Impurity C can be found in natural products, but also synthesized in laboratories.</p>

<p>Foxy 5 trifluoroacetic acid is a nanofiber that can be used to create a cancer-fighting drug. It is made of polymers and has been shown to have the ability to absorb electromagnetic fields from all directions. Foxy 5 trifluoroacetic acid is packaged in a small, easy-to-handle container that releases the drug when the package is positioned against the tumor. This drug can be used for colon cancer and colorectal cancer because it targets only cells with efflux proteins, which are proteins that promote cancer cell metastasis. In addition, Foxy 5 trifluoroacetic acid has been shown to be effective against prostate and breast cancers by targeting specific receptors on these cells.</p>

<p>Profluthrin is a potent analog of the Chinese medicinal herb, Chrysanthemum indicum. It acts as an inhibitor of protein kinases involved in the regulation of cell cycle and apoptosis. Profluthrin has been shown to have anticancer properties by inducing apoptosis in cancer cells and inhibiting tumor growth. This compound also shows potential as a urinary inhibitor for the prevention of urinary tract infections. Its unique chemical structure allows it to act selectively on specific protein kinases, making it a promising candidate for targeted cancer therapy.</p>

<p>6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide is a high purity drug product. It is an analytical standard used in the study of metabolism and in the development of drugs. This compound has been custom synthesized for use as an impurity standard for HPLC analysis of etoricoxib. 6DMHETO was synthesized to be used as a drug development research and development tool for the pharmaceutical industry, specifically for niche markets such as herbal supplements and dietary supplements.</p>

<p>Please enquire for more information about 4-[(3-Chlorophenyl)sulfonyl]benzenamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-[2-[4-[(2,4-Dioxo-5-thiazolidinyl)methyl]phenoxy]ethyl]-3-pyridineacetic acid is a drug product that has been custom synthesized by our in-house chemists. It is a high purity chemical with an analytical purity of 98%. It is also CAS No. 146062-48-8 and can be found in the pharmacopoeia. This compound has been studied for metabolism studies and drug development. The metabolite is natural and its impurity standard is met by HPLC standards.</p>

<p>N-(Aminosulphonyl)-2-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methylsulphinyl]propanimidamide (NTSX) is an analytical standard and a metabolite of the drug product N-(aminosulphonyl)-2-[[[2-[(aminothiazolyl)methyl]sulfinyl]propanimidamide (NTST). The CAS number is 109467-06-3. NTSX is a white to off-white crystalline powder that is soluble in water and has a molecular weight of 296.37. It has been shown to be active against ampicillin resistant strains of Staphylococcus aureus, but not against methicillin resistant strains. NTSX can be synthesized from the drug NTST or obtained as an impurity from the synthesis of NTST.</p>

<p>Rosuvastatin is a natural, synthetic and semi-synthetic drug product. It is the active ingredient in an investigational drug called Iressa. Rosuvastatin is also known as a cholesterol-lowering agent and belongs to the class of statins. Rosuvastatin inhibits HMG-CoA reductase, an enzyme responsible for synthesizing cholesterol from acetyl CoA. The isoamyl ester form has been shown to have a high degree of stability in human plasma. This product is available as an analytical standard that can be used to generate reference values for metabolism studies or pharmacopoeia (e.g., USP).</p>

<p>4-Carboxy-3-ethoxy)phenyl acetic acid (CPAE) is a fluorescent compound that has been shown to have antidiabetic and luminescence properties. It absorbs light at wavelengths of 340, 405, and 455 nm and emits light at 525 nm. It also absorbs UV light at 310 nm and emits fluorescence at 495 nm. CPAE is formed by the condensation of two molecules of 4-carboxybenzaldehyde with one molecule of ethyl 3-ethoxypropanoate in the presence of a base. The crystals are monoclinic, with space group P2/c and lattice constants a = 12.872(1) Å, b = 7.319(1) Å, c = 17.814(2) Å, β = 98.664(9)°, Z = 2. The molecular weight is 182.24 g/mol and its molecular</p>

<p>Loxoprofen Related Compound 2 is a mixture of diastereomers that is an impurity in the drug product, Loxoprofen. Loxoprofen Related Compound 2 is a metabolite of loxoprofen and its concentration in blood plasma after administration of loxoprofen can be used as an indicator for pharmacokinetics. The compound has been shown to inhibit the activity of bacterial dna gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. Loxoprofen Related Compound 2 was found to be less active than loxoprofen against MRSA and Clostridium perfringens, although it was more active than loxoprofen against Mycobacterium tuberculosis, Mycobacterium avium complex, and methicillin-resistant Staphylococcus aureus (MRSA).</p>

<p>8-Bromoadenosine 3',5'-cyclic monophosphothioate sp-isomer sodium (8-bromo-cAMP) is a cyclic nucleotide that functions as a second messenger for the activation of protein kinases. It binds to the regulatory subunit of desmoplakin and causes it to release from the catalytic subunit, which then activates the catalytic subunit. 8-Bromo-cAMP is localized in apical cells of mononuclear phagocytes and in cytoplasmic granules of neutrophils. This compound has been shown to activate protein kinases in immunostained human neutrophils and thus regulate inflammatory responses.</p>

<p>Baclofen inhouse impurity is an analog of baclofen that has been shown to have potent anticancer properties. It acts as a kinase inhibitor, specifically inhibiting the activity of certain kinases that are involved in cancer cell growth and proliferation. In preclinical studies, this compound has demonstrated significant tumor growth inhibition and induction of apoptosis in human cancer cell lines. This medicinal compound is commonly used in Chinese medicine for its anti-cancer effects. Baclofen inhouse impurity can be isolated from urine or synthesized chemically. Its potential as a protein kinase inhibitor makes it a promising candidate for further development as an anticancer agent.</p>

<p>Torasemide Impurity E is a drug product that belongs to the group of impurities. It is a natural product and can be found in the environment. Torasemide Impurity E has been shown to inhibit bacterial growth in vitro and also antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus. Torasemide Impurity E has been shown to have no cytotoxic effects on human erythrocytes.</p>

(R,R)-Dihydro bupropion hydrochloride is a synthetic compound that has been developed for the treatment of depression and nicotine addiction. This drug is metabolized by liver enzymes to form two metabolites: (S,S)-dihydro bupropion and (R,S)-hydroxybupropion. The pharmacopoeia defines the purity of this product as > 98%, with an impurity standard of 1%. This compound is not found in nature. It is available as a research and development grade product or as a custom synthesis upon request.

<p>HSL-IN-1 is an inhibitor analog of nalbuphine that has shown potential as an anticancer agent. It works by inhibiting the activity of certain kinases that are involved in tumor growth and survival. HSL-IN-1 induces apoptosis, or programmed cell death, in cancer cells by disrupting their protein synthesis and causing DNA damage. This compound has been found to be effective against a variety of human cancers, including breast, lung, and colon cancer. HSL-IN-1 is derived from Chinese medicinal urine and is one of several promising inhibitors currently being studied for their potential use as anticancer agents.</p>

<p>N-Propyl-1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-2-propenamide is a drug that belongs to the group of beta blockers. It inhibits the action of catecholamines on β receptors, which in turn reduces cardiac output, heart rate and myocardial oxygen consumption. N-Propyl-1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-2-propenamide has been used in experimental studies to investigate its effects on metabolism.</p>

<p>Please enquire for more information about N-Desmethyl eletriptan hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-Chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester is a synthetic compound that has not been evaluated in humans. Studies have shown that the drug can be hydrolyzed to 7-chloro-6-fluoroquinoline 1,1′-(ethylenedioxy)bis(ethane), which is an impurity of norfloxacin. The ethyl esters of 7-chloroquinoline are also known to condense with formaldehyde and hydrolyze to 7-chloroquinolinic acid. This product may contain solvents such as acetone, chloroform, and alcohols that are used during the synthesis process. Decarboxylation of the drug occurs when it is heated at high temperatures in the presence of a catalyst, such as pyridine or sodium methoxide. It decarboxyl</p>