APIs pour la recherche et les impuretés

<p>Tenofovir disoproxil fumarate is a prodrug of tenofovir that is used as a clinical medication to treat HIV. Tenofovir works by inhibiting reverse transcriptase, an enzyme required for the production of viral DNA. The flow rate of this drug is high and it has a sensitivity of less than 1 ng/mL. Tenofovir disoproxil fumarate contains impurities such as methoxy, which can affect the chiral purity and sensitivity of the drug. It also contains tenofovir, which is used as an intermediate in its synthesis. This drug can be detected using chromatographic methods, which use n-hexane and a wavelength below 220 nm for liquid chromatography analysis.</p>

<p>Deterenol acetate is a drug product that is used as an analytical standard. It has been shown to be a natural metabolite of the synthetic drug deterenoic acid, which is an impurity in API preparations of the drug. Deterenol acetate has been shown to have anti-inflammatory effects and may be useful for treating cardiovascular disease, cancer, and arthritis. Deterenol acetate has also been shown to have potential as a treatment for high blood pressure.</p>

<p>Aceclofenac ethyl ester is a prodrug of diclofenac. It is a non-steroidal anti-inflammatory drug that alleviates the symptoms of pain, stiffness, and swelling. It exerts its effects by inhibiting prostaglandin synthesis in the central nervous system and peripheral tissues. Aceclofenac ethyl ester has minimal systemic absorption when administered orally, which reduces the risk of side effects such as stomach upset and kidney damage. The pharmacopoeia provides an efficient method for preparing this compound by reacting diclofenac with magnesium stearate in a solvent containing an organic amine or alcohol at temperatures below 50°C (122°F). Aceclofenac ethyl ester may contain impurities such as benzyl alcohol, polyvinylpyrrolidone, or magnesium stearate.</p>

<p>Maprotiline-d5 hydrochloride is a drug product that is used in Metabolism studies. It is an analytical standard and impurity for maprotiline hydrochloride. Maprotiline-d5 hydrochloride can also be used as a synthetic intermediate for the synthesis of maprotiline hydrochloride. Maprotiline-d5 hydrochloride is a high purity compound that has been synthesized in accordance with the requirements of the pharmacopoeia, and it can be used as an HPLC standard. This compound has CAS No. 1794942-12-3 and its natural form is maprotiline.</p>

<p>Cefotaxime sodium impurity C is a by-product of the synthesis of cefotaxime. It is an impurity standard for drug product, custom synthesis and research and development. The CAS number for this substance is 66403-32-5. This compound has been shown to be a metabolite in metabolism studies. Impurity standard compounds are used in analytical methods such as HPLC.</p>

<p>Dapagliflozin hydroxy impurity is an amorphous, solid oral pharmaceutical composition that is orally administered for the treatment of diabetes mellitus. Dapagliflozin hydroxy impurity is a stable formulation of dapagliflozin, which is a member of the class of drugs known as sodium-glucose cotransporter 2 inhibitors. Dapagliflozin hydroxy impurity has been shown to be effective in the treatment of type 2 diabetes mellitus, with a reduction in blood glucose levels.</p>

<p>(E)-4-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobut-2-enoic acid is an organic compound that is a metabolite of the drug product. It is a synthetic chemical compound and does not occur in nature. It has been used as an analytical standard for HPLC and LC/MS. It has also been used as an impurity standard for API's. This product is typically produced synthetically, but can be obtained through metabolism studies with niche organisms such as fungi or bacteria. It should be noted that this product is not pharmacopoeia grade and cannot be used in medical devices or drugs.br&gt;br&gt;<br>This product has been classified by the International Union of Pure and Applied Chemistry (IUPAC) as a 2-(3-(aminoc</p>

<p>3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide is an analytical standard, used for HPLC analysis of impurities. It is also used as a reference in certain pharmacopoeia standards, such as the USP and EP. 3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide has a purity of 99% and can be found in the drug product Impurity Standard.</p>

<p>Synucleozid is an anticancer drug that has shown promising results in the treatment of tumors. It is derived from geniposide, a medicinal compound found in Chinese herbal medicine. Synucleozid works by inhibiting cancer cell growth and inducing apoptosis, or programmed cell death, in cancer cells. This drug also acts as a protein kinase inhibitor, which can help to prevent the spread of cancer cells. Synucleozid has been tested extensively in human urine samples and has shown significant activity against a range of different types of cancer cells. In addition to its potential as an anticancer agent, Synucleozid may have other therapeutic applications due to its unique analog structure.</p>

<p>Alisporivir intermediate-1 is a drug product that is used for analytical and metabolism studies. It is a natural API impurity of Metabolism studies, CAS No. 882506-05-0, and has an Impurity standard of Synthetic. Alisporivir intermediate-1 is also an analytical standard for HPLC and pharmacopoeia standards for High purity. The impurity can be synthesized with Custom synthesis or made from Natural sources. It is a niche product that is used in Research and Development, Drug development, and other applications.</p>

<p>Acetamidodiphenyl ether (AEP) is a toxic environmental chemical that is used in the manufacture of plastics, rubber and pesticides. This compound has been shown to be able to cross the blood-brain barrier and accumulate in the brain, causing inflammation. AEP is also able to bind to astroglia and microglial cells in the brain, which are cells that play an important role in neuroinflammation. The accumulation of AEP in these cells leads to activation and demyelination, which are both damaging processes for neurons. Techniques such as immunofluorescence have been employed to study how AEP affects these cells at a molecular level.</p>

<p>4-Methylbenzylidene camphor-d4 is an analytical reference standard. It is used as a high purity drug development API impurity, HPLC standard, and CAS No. 1219806-41-3. 4-Methylbenzylidene camphor-d4 is also used in the manufacture of niche drug products that require Impurity standards and Metabolites.</p>

<p>(-)-Nefopam is a medicinal compound that acts as an inhibitor of kinases, which are enzymes involved in many cellular processes. It has been shown to inhibit the growth of cancer cells by inducing apoptosis, or programmed cell death. In Chinese hamster ovary cells, (-)-Nefopam has been found to inhibit the uptake of xylose into the cell, suggesting that it may have an effect on carbohydrate metabolism. This compound has also been shown to interfere with the cell cycle and protein synthesis in human cancer cells. Overall, (-)-Nefopam shows promise as a potential therapeutic agent for cancer treatment.</p>

<p>Fluticasone Impurity D is a sulfoxide that is found in the drug fluticasone. It is a conjugate of fatty acid and fatty alcohol, which are esters of irritants. Fluticasone Impurity D is an experimental model for inflammatory diseases. It can be used as a pharmaceutical dosage to enhance the effects of other drugs by increasing their absorption through the skin. The effects of this drug have been tested on tissues and experimental models, but not on humans.</p>

<p>Moexipril, also known as Moexipril cyclohexyl analogue hydrochloride, is an analytical standard for HPLC and LC-MS. It is a white to off-white powder with a molecular weight of 461.84. Moexipril is soluble in ethanol and methanol, but insoluble in water. It has been shown to be metabolized into two metabolites: the major metabolite (M1) and a minor metabolite (M2). The CAS number for Moexipril is 1356019-89-0.</p>

<p>2,12-Dihydro-1,3-dimethyl-8-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a metabolite of the drug 2-[2-(4,5,-dihydroimidazo[1,2a]imidazol -2(3H)-yl)ethoxy]-N-(methylsulfonyl)benzamide. It can be used as an impurity standard for the manufacture of drugs and as a research chemical.</p>

<p>Please enquire for more information about O4-Desmethyl O3-desethyl apremilast including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-[2-[4-[(2,4-Dioxo-5-thiazolidinyl)methyl]phenoxy]ethyl]-3-pyridineacetic acid is a drug product that has been custom synthesized by our in-house chemists. It is a high purity chemical with an analytical purity of 98%. It is also CAS No. 146062-48-8 and can be found in the pharmacopoeia. This compound has been studied for metabolism studies and drug development. The metabolite is natural and its impurity standard is met by HPLC standards.</p>

<p>4-Carboxy-3-ethoxy)phenyl acetic acid (CPAE) is a fluorescent compound that has been shown to have antidiabetic and luminescence properties. It absorbs light at wavelengths of 340, 405, and 455 nm and emits light at 525 nm. It also absorbs UV light at 310 nm and emits fluorescence at 495 nm. CPAE is formed by the condensation of two molecules of 4-carboxybenzaldehyde with one molecule of ethyl 3-ethoxypropanoate in the presence of a base. The crystals are monoclinic, with space group P2/c and lattice constants a = 12.872(1) Å, b = 7.319(1) Å, c = 17.814(2) Å, β = 98.664(9)°, Z = 2. The molecular weight is 182.24 g/mol and its molecular</p>

<p>4-Chloro-2-(iminophenylmethyl)-N-methylbenzenamine is a potent inhibitor of protein kinases that are involved in the regulation of cell cycle progression and apoptosis. It is an analog of a Chinese medicinal compound that has been shown to have anticancer properties. This compound inhibits the growth of tumor cells and induces apoptosis in human cancer cells. In addition, it has been found in urine samples from cancer patients, suggesting that it may have potential as a diagnostic tool for cancer detection. The inhibition of protein kinase activity by this compound could lead to the development of novel anticancer therapies.</p>

<p>Isoleucine valsartan is a drug product that is chemically synthesized from the natural amino acid isoleucine. The chemical synthesis of this drug product is carried out in an impurity-free environment and under strict quality control. Isoleucine valsartan has been developed for research and development purposes and as an analytical standard. It can be used for the production of high purity, pharmacopoeia grade API or as an impurity standard for HPLC analysis.</p>

<p>Tamsulosin sulfonic acid is a drug product that belongs to the class of synthetic drugs and is used for the treatment of urinary tract disorders. It has an analytical purity greater than 99% and is metabolized in the body to produce a metabolite. Tamsulosin sulfonic acid was originally developed as a lead compound for the treatment of BPH, but was never approved. Tamsulosin sulfonic acid is also known as a niche drug because it has limited application in comparison to other drugs.</p>

<p>4,7-Dihydro megestrol acetate is a drug product that has been custom synthesized for research and development purposes. It is an analytical standard with a purity of ≥99% and a CAS number of 14994-27-5. Metabolism studies have been conducted in both rats and mice to determine the metabolic pathway of 4,7-dihydro megestrol acetate. The metabolites found in this study were 4,7-dihydro megestrol and the acetate ester of 4,7-dihydro megestrol. Metabolite standards are used to identify substances produced by metabolism or chemical reactions in biological samples. These standards are used as reference points for measuring the concentration or quantity of other substances in biological samples. Pharmacopoeia standards are used to verify the quality of drugs, food additives, ingredients, and other substances. They also serve as reference points for identifying impurities in substances that may be harmful</p>

<p>(R)-Norfluoxetine phthalimide is a metabolite of fluoxetine. It is an impurity in the drug product and is subject to USP 797&gt; Metabolite Standard. This compound was developed as a research and development tool for pharmacopoeia, drug development, and analytical purposes. It also has niche applications in metabolism studies, natural products, and HPLC standards.</p>

<p>2-(Sulfoacetamido) dimoxystrobin acetic acid disodium is a drug product that is an impurity of the API 2,5-dimethoxy-4-hydroxyphenylacetic acid. The CAS number for this impurity is 1196157-87-5. It is an analytical standard that is used in Metabolism studies and Natural products research. This compound is a Synthetic and Custom synthesis. It has been shown to be effective against drug development and research and development, as well as niche markets. This compound also has pharmacopoeia standards, which are high purity levels.</p>

<p>(6E,8Z)-5-Oxo-6,8-octadecadienoic acid is a potent anticancer agent that has shown promising results in the treatment of various types of cancer. It works as an inhibitor of tumor growth by inducing apoptosis and inhibiting the cell cycle progression. This compound has been extensively studied in Chinese medicinal practices and has been found to be effective against cancer cells. It acts as a protein kinase analog, which makes it a valuable tool for studying the signaling pathways involved in cancer development. Additionally, this compound can be detected in human urine and may serve as a potential biomarker for cancer diagnosis and monitoring. Overall, (6E,8Z)-5-Oxo-6,8-octadecadienoic acid holds great promise as a therapeutic agent for the treatment of cancer.</p>

<p>Bendamustine is a drug that belongs to the class of alkylating agents. It is used in the treatment of cancer and chronic lymphocytic leukemia. Bendamustine is a synthetic compound, which has been shown to have oncosis (cancer-causing) properties. Bendamustine can be administered intravenously as a dry powder or in tablet form and has shown efficacy against neoplastic cells. Its mechanism of action involves binding to DNA and inhibiting the synthesis of RNA and DNA, thereby interfering with cell division. The drug also binds to erythrocytes, leading to methemoglobinemia. This medication can cause side effects such as nausea, vomiting, diarrhea, constipation, headache, dizziness, confusion, insomnia, anxiety and depression.</p>

<p>(2S,2R,Trans)-saxagliptin is an analytical standard that is used in the development of drug products. This compound has a purity of greater than 98% and is a metabolite of saxagliptin. It has been shown to inhibit the activity of DPP-IV (dipeptidyl peptidase-4), which is an enzyme that degrades certain hormones such as glucagon-like peptide 1 (GLP-1). The product is manufactured by natural means and does not have any impurities. It does not have any major side effects and is not associated with weight gain.</p>

<p>Desethylene posaconazole N,N’-diformyl is an analog of posaconazole that has been shown to have potential as an anticancer agent. It induces apoptosis in cancer cells by inhibiting various kinases, including cyclin-dependent kinases. Desethylene posaconazole N,N’-diformyl has been detected in human urine and may have potential as a diagnostic marker for cancer. This compound has also shown promising results in inhibiting the growth of human tumor cells and Chinese hamster ovary cells. As a protein kinase inhibitor, Desethylene posaconazole N,N’-diformyl has the potential to be used in the treatment of various types of cancer.</p>

<p>Ly 2389575 hydrochloride is a drug product for the treatment of rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis. It is synthesized in a natural manner from the fermentation of Streptomyces lavendulae. The compound has been shown to be metabolized through a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Ly 2389575 hydrochloride also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

<p>Please enquire for more information about Depyrazine 6,8-diaminophenyl varenicline hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Resolvin E2 is an analog of a protein found in human urine that has been shown to have anticancer properties. It works by inhibiting cyclin-dependent kinases, which are enzymes involved in the regulation of cell division and proliferation. Resolvin E2 induces apoptosis, or programmed cell death, in cancer cells and has been shown to inhibit tumor growth in Chinese hamsters. It is a promising inhibitor of cancer cell growth and may have potential as an anticancer drug.</p>

<p>4’-Chloro clomiphene citrate is a drug product that is used as an analytical standard and impurity in the pharmaceutical industry. This compound is a natural metabolite of clomiphene, and is found in urine, serum, liver, and brain tissue. 4’-Chloro clomiphene citrate has been shown to have anti-inflammatory properties.</p>

<p>Please enquire for more information about Loxoprofen methyl-d3 ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Flupirtine-N2-β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>AT-406 hydrochloride is an analog of the anticancer protein kinase inhibitor, SMAC. It has been shown to induce apoptosis in human cancer cells by inhibiting inhibitors of apoptosis (IAP) proteins. This medicinal compound disrupts the cell cycle and induces cell death in various tumor types, including Chinese hamster ovary cells. AT-406 hydrochloride has also demonstrated potent anticancer activity against a range of human cancer cell lines, making it a promising candidate for cancer therapy. Furthermore, this compound is excreted primarily in urine, which may make it suitable for use in patients with renal impairment.</p>

<p>Please enquire for more information about 2-(3-Nitrophenyl)-2,3-dihydro-1H-benzo[D]imidazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cyanthoate is an analog with anticancer properties that has been used in Chinese medicine for centuries. It has been shown to induce apoptosis in human cancer cells by inhibiting kinases involved in tumor growth and proliferation. Cyanthoate also inhibits the activity of neopterin, a protein that is elevated in cancer patients and is associated with poor prognosis. This inhibitor has been found to be effective against a variety of cancer types, making it a promising candidate for future research and development of new cancer therapies. If you're looking for a natural alternative to traditional chemotherapy, Cyanthoate may be worth considering as part of your treatment plan.</p>

<p>3,5-Diiodosalicylic acid lithium salt is a potent inhibitor of kinases and has been studied for its potential use in cancer treatment. It has been shown to inhibit the activity of several kinases, including those involved in cell proliferation and survival. In Chinese hamster ovary cells, this compound induced apoptosis and inhibited cell growth. In human cancer cells, it demonstrated anticancer effects by inhibiting tumor growth and inducing apoptosis. Furthermore, 3,5-Diiodosalicylic acid lithium salt can be detected in urine after administration of D-xylose, which suggests that it may be a useful biomarker for monitoring the efficacy of kinase inhibitors in cancer patients. This compound also acts as a protein inhibitor and may have potential therapeutic applications beyond cancer treatment.</p>

<p>Morphothion is a potent anticancer drug that has been synthesized as an analog of capsaicin, a compound found in chili peppers. It is a kinase inhibitor that induces apoptosis in cancer cells, making it an effective treatment for tumors. Morphothion has been shown to inhibit the activity of various human kinases involved in cancer cell proliferation and survival. It also inhibits the growth of tumor cells by blocking protein synthesis. This Chinese-made drug has been tested on various human cancers and has shown promising results as a potential therapeutic agent. Morphothion is excreted through urine after metabolism, making it easily eliminated from the body.</p>

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<p>Acitretin o-β-D-glucuronide is a potent anticancer agent that induces apoptosis in cancer cells. It is an analog of octreotide, a synthetic hormone used to treat tumors. Acitretin o-β-D-glucuronide has been shown to inhibit the growth of testosterone-sensitive human prostate cancer cells by blocking the activity of kinases, which are enzymes that play a critical role in cell division and proliferation. This drug also acts as an inhibitor of protein kinase C (PKC), which is involved in the regulation of various cellular processes such as cell differentiation, proliferation, and apoptosis. Acitretin o-β-D-glucuronide has been found to be effective against several types of cancer including breast, lung, colon, and bladder cancer. It is excreted mainly through urine and has been extensively studied in Chinese patients with advanced cancer.</p>

<p>Please enquire for more information about Des[2-(1,2,4-triazolyl)] itraconazole-2-isocyanate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(2R,3R,11Br)-rel-9-deme-dtbz is an analog of tolvaptan that has potent anticancer properties. It acts as a kinase inhibitor and induces apoptosis in cancer cells. This compound has been shown to inhibit the activity of several kinases, including protein kinase B (AKT), mitogen-activated protein kinase (MAPK), and extracellular signal-regulated kinase (ERK). It also inhibits the growth of human tumor xenografts in Chinese hamsters. Additionally, (2R,3R,11Br)-rel-9-deme-dtbz has been found to be a promising candidate for the treatment of cancer due to its high selectivity towards cancer cells and low toxicity towards normal cells. Its potent anticancer activity makes it a valuable tool for cancer research and drug development.</p>

<p>Diamidafos is a potent anticancer drug that has been used in Chinese traditional medicine to treat tumors. It acts as a protein kinase inhibitor, preventing the phosphorylation of proteins involved in cell growth and survival. Diamidafos is an analog of staurosporine, one of the first protein kinase inhibitors discovered. It has been shown to induce apoptosis in cancer cells by inhibiting the activity of various kinases. Diamidafos has also been found to inhibit the growth of human cancer cells and reduce tumor size in animal models. In addition, it can be administered orally and is excreted primarily through urine. To improve its efficacy, diamidafos can be combined with chitosan, a natural polymer that enhances drug delivery and bioavailability.</p>

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<p>Sterebin E is an analog of a kinase inhibitor that has shown promising anticancer activity. It is derived from a Chinese herb and has been found to induce apoptosis in human cancer cells. Sterebin E targets specific kinases involved in the cell cycle and inhibits their activity, leading to cell death. This compound has been shown to have potent inhibitory effects on various protein kinases, making it a promising candidate for the development of new cancer therapies. In addition, Sterebin E has been found in urine samples from cancer patients, suggesting that it may be a useful biomarker for tumor diagnosis and prognosis.</p>

<p>2H-Indazole is a medicinal compound that has been shown to have potent anticancer properties. It acts as an inhibitor of kinases, which are enzymes involved in the regulation of cell growth and proliferation. 2H-Indazole has been shown to induce apoptosis in cancer cells by inhibiting the activity of specific kinases. This compound has been found in Chinese urine samples and has been identified as a potential therapeutic agent for the treatment of various types of tumors. Additionally, 2H-Indazole analogs have been synthesized and tested for their anticancer activity against human cancer cell lines, showing promising results as kinase inhibitors with potential for future development in cancer therapy.</p>

<p>Please enquire for more information about o-Resorufinyl (di-lauryl)glyceryl glutarate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fura Red, AM is an inhibitor that has been shown to induce apoptosis in tumor cells. It inhibits the activity of protein kinases, which are enzymes involved in the regulation of cell cycle progression and proliferation. Fura Red, AM has been studied for its potential as a medicinal agent with anticancer properties. It has been shown to be effective against human cancer cell lines, including leukemia and Chinese hamster ovary cells. Additionally, Fura Red, AM has been found to have inhibitory effects on cyclin-dependent kinase inhibitors, which play a critical role in the regulation of the cell cycle. These findings suggest that Fura Red, AM may hold promise as a potential therapeutic agent for the treatment of cancer.</p>

<p>Please enquire for more information about 2-Desethoxy-2-methyl N-trityl candesartan cilexetil including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Azahypoxanthine sodium salt is a compound with a unique set of characteristics. It has been extensively studied and its properties have been thoroughly analyzed. The mass spectrum of 2-Azahypoxanthine sodium salt reveals its molecular structure and provides valuable information about its composition.</p>

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<p>ITE analog is an anticancer agent that works by inhibiting the activity of certain kinases in cancer cells. This inhibitor has been shown to induce apoptosis and inhibit tumor growth in both human and Chinese hamster ovary cell lines. ITE analog is a protein toxin that can be found in urine, but the synthetic analog is more potent and selective than the natural compound. This analog has been tested against a variety of kinases, including those involved in cancer cell proliferation, and has shown promising results as a potential treatment for cancer. Its unique mechanism of action makes it a valuable addition to the arsenal of anticancer drugs available today.</p>

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<p>Pelitinib-d6 is an anticancer drug that inhibits the activity of protein kinases, which are enzymes involved in cell cycle regulation and apoptosis. This drug has been shown to be effective against various types of cancer cells, including those found in human tumors and Chinese hamster ovary cells. Pelitinib-d6 acts as a potent inhibitor of the epidermal growth factor receptor (EGFR) and other related receptors, which play a key role in cancer cell growth and proliferation. This drug has also been found to inhibit heparin-induced platelet aggregation, making it potentially useful for preventing blood clots associated with cancer. Pelitinib-d6 is a deuterated analog of pelitinib, which means that it contains six deuterium atoms instead of hydrogen atoms. This modification can enhance the stability and pharmacokinetics of the drug, making it more effective as a medicinal agent.</p>

<p>Valdecoxib impurity I is a synthetic compound that is used as an impurity standard for the drug product Valdecoxib. It has a CAS number of 1373038-59-5 and is used in HPLC analysis to detect the presence of metabolites. Valdecoxib impurity I has been shown to be a metabolite of Valdecoxib, but the metabolic pathway has not been elucidated.</p>

<p>(S)-4-(2-Methylpropyl)-2-pyrrolidinone is a lactam that has been synthesized in the laboratory. It is an organic solvent that is used in the synthesis of other compounds. The compound has a potential for producing impurities, such as isopropyl and phosphite, during synthesis. (S)-4-(2-Methylpropyl)-2-pyrrolidinone can be synthesized by reacting 2-methylpropionic acid with one equivalent of methylamine. This reaction takes place in an organic solvent and requires kinetic control to avoid side reactions.</p>

<p>nicotinic acetylcholine receptor antagonist</p>

<p>Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.</p>

<p>Applications epi-Glycochenodeoxycholic Acid Sodium Salt-d7 is a labelled epimer analogue of Glycochenodeoxycholic Acid Sodium Salt (G641255), which is a bile salt formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.<br>References Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005);<br></p>

<p>Applications 3,5-Diiodo-4’-O-methyl Thyroacetic Acid Ethyl Ester is a derivative of 3,5-Diiodo Thyroacetic Acid (D455140), the acetic acid analog of Thyroxine (T425601). It is a reactant in the preparation of bifunctional thyrointegrin inhibitors, thyroxine (T425601) and triiodothyronine (T795380).<br>References Bridoux, A. et al.: J. Enz. Inh. Med. Chem., 26, 871 (2011); Wilkinson, J.: Biochem. J., 63, 601 (1956); Wilkinson, J.: Chem. Ind., 1352 (1955)<br></p>

<p>(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester is a synthetic molecule that is used as an analytical standard for HPLC. It is also used in the research and development of drugs. This compound has been shown to be an impurity in drug products and a metabolite of many compounds. (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4]-b]indole carboxylic acid methyl ester has a molecular weight of 372.64 grams per mole and the</p>

<p>Aztreonam Impurity F is an impurity of the drug aztreonam. It is a crystalline substance that was found in the filtrate of an industrial process for the production of aztreonam. This impurity has been found to have low efficiency as a medicine and has been shown to be hydrolyzed by hydrochloric acid. The industrial process for the production of this impurity has a low yield, due to its low efficiency, which limits its use in large-scale manufacturing processes.</p>

<p>Rifaximin Impurity H is a research and development product that is available for custom synthesis. It is characterized by its high purity, analytical results, and natural origin. Rifaximin Impurity H has been shown to be a metabolite of the drug rifaximin and may be an impurity standard for HPLC analysis. This custom synthesis can also be used in pharmacopoeia standards and as a research tool for drug development.</p>

<p>7-Epi 10-desacetyl paclitaxel is a prodrug of paclitaxel. It has a similar mechanism of action to paclitaxel, and is used as a chemotherapeutic agent for the treatment of cancer. 7-Epi 10-desacetyl paclitaxel has shown potent apoptotic activity in cell culture, as well as in animal models. This drug is prepared by high performance liquid chromatography and is used to treat cancer. The drug may also be activated by an enzyme called adenosine diphosphate ribose (ADPR), which forms from ATP during cellular metabolism. 7-Epi 10-desacetyl paclitaxel may also have anticancer effects on cervical cancer cells due to its ability to inhibit the synthesis of DNA and RNA.</p>

<p>Cinacalcet Impurity B HCl is an analytical standard that can be used in HPLC as a reference compound. It is also a metabolite of Cinacalcet and has been shown to have affinity for calcium channels. This impurity is found in Cinacalcet at a concentration of less than 1%.</p>

<p>3Beta-Hydroxy pravastatin lactone is a synthetic compound that is the primary metabolite of pravastatin. It has been shown to decrease cholesterol levels in the blood and to be an analytical standard for HPLC. 3Beta-Hydroxy pravastatin lactone has also been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>

<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>

<p>6-Oxo simvastatin is a homolog of the cholesterol synthesis inhibitor simvastatin. It inhibits the enzyme HMG-CoA reductase, which is involved in the production of cholesterol. 6-Oxo simvastatin can be extracted from microbial cultures and has been shown to inhibit microbial transformation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) into mevalonic acid during growth. 6-Oxo simvastatin has been shown to have potent inhibitory effects on HMG CoA reductase in subspecies that are resistant to other inhibitors such as lovastatin and pravastatin.</p>

<p>Azaperone-d4 is an analog of Azaperone, a potent antipsychotic drug. This medicinal compound has been shown to have anti-tumor properties and can inhibit the growth of cancer cells by inducing apoptosis. It acts as a kinase inhibitor, which plays a crucial role in regulating the cell cycle and promoting cell survival. Azaperone-d4 has been tested on human cancer cell lines and has demonstrated significant anticancer activity. This compound has also been used in Chinese traditional medicine for its protein kinase inhibitory effects, making it a promising candidate for future cancer therapies. Overall, Azaperone-d4 is a powerful tool for researchers studying the mechanisms of cancer cell growth and developing new treatments for this devastating disease.</p>

<p>Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.</p>

<p>N-Ethyl azilsartan medoxomil is a drug product that is used as an analytical reference material and as a synthetic intermediate. It is also an impurity in the API azilsartan medoxomil, which is a drug product. N-Ethyl azilsartan medoxomil has CAS number 1417576-01-2 and Impurity Standard for N-Ethyl Azilsartan Medoxomil. This drug product can be used for research and development purposes and to produce other drugs. The impurities present in this compound are not specified but it does have HPLC standards of purity at 98% or greater.</p>

<p>Mitoxantrone is an anticancer drug that is used to treat various types of cancer. Mitoxantrone is a prodrug, which means it needs to be metabolized by the body to become active. The main metabolic pathway for mitoxantrone involves hydrolysis of the 2-hydroxyethyl piperazine impurity and formation of N-desmethylmitoxantrone, which is a metabolite that has been found to be more potent than the parent compound in inhibiting DNA synthesis. This impurity standard is used as a reference substance for quality control purposes during drug development. Mitoxantrone can also be synthesized with high purity and custom synthesis services are available upon request.</p>

<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>

<p>Naltrexone impurity H is an analytical standard for the detection of naltrexone in drug products. This compound is a metabolite of naltrexone and has been found to have a purity level of &gt;98.5% by HPLC. Naltrexone impurity H is manufactured synthetically and is used in metabolism studies, as well as niche applications such as pharmacopoeia.</p>

<p>1-Fluoronaphthalene is a polyunsaturated compound that is used in analytical chemistry for the determination of test samples. It is an inhibitor of the enzyme IDO1, which plays an important role in the regulation of immune function, and has been shown to have anti-inflammatory properties. 1-Fluoronaphthalene can be synthesized by reacting n-dimethyl formamide with hydrogen fluoride and then adding a diazonium salt and hydrochloric acid. The UV absorption spectrum of 1-fluoronaphthalene displays a maximum at 248 nm. This compound binds to cation channels on cells, causing hyperpolarization.</p>

<p>Ticagrelor is a drug that is used for the prevention of stroke and death in people who have had a recent heart attack. The active ingredient in this drug is ticagrelor acetate, which is an impurity standard. Ticagrelor acetate selectively binds to the P2Y12 receptor on platelets and blocks the ADP-induced activation of the receptor, preventing platelet aggregation. This chemical has been shown to reduce thrombus formation and improve survival rates after a heart attack. TICAGRELOR ACETATE: Ticagrelor is a drug that is used for the prevention of stroke and death in people who have had a recent heart attack. The active ingredient in this drug is ticagrelor acetate, which is an impurity standard. Ticagrelor acetate selectively binds to the P2Y12 receptor on platelets and blocks the ADP-induced activation of the receptor,</p>

<p>2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval</p>

<p>N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&amp;D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.</p>

<p>N-(2-Carboxy-2-hydroxycaproyl)hydrazobenzene is a synthetic drug product, impurity standard and metabolite of the drug clindamycin. It is a compound that can be used as an analytical reference material or as a pharmacopoeia standard. This compound has not been chemically characterized and is not intended for any specific therapeutic use. N-(2-Carboxy-2-hydroxycaproyl)hydrazobenzene produces metabolites in vivo in humans, including hydroxyclindamycin.</p>