Peptides

SK channels blocker

Ovotransferrin 328-332, also called Conalbumin 328-332, is a part of the egg white albumen.

Insects paralysis and death

Muscle-type nAChRs blocker

Angiotensin-converting enzyme 2 (ACE2) is an enzyme involved in the cardiovascular system by decreasing arterial pressure by catalyzing the conversion of angiotensin II to angiotensin (1-7). Angiotensin II is a vasoconstrictor and angiotensin (1-7) is a vasodilatator. This effect makes ACE2 a therapeutic target for cardiovascular disease.

NERP-1 (Human) modulates body fluid homeostasis and suppresses vasopressin release

Primary SIL peptide for Dinutuximab detection and quantification

The Nucleocapsid Protein (N-protein), also called coronavirus nucleocapsid (N), is the most abundant protein in coronavirus. It is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus transcription and assembly.

mouse Beta-Defensin 3 peptide (mBD3), a homolog of human beta-defensin 2 (hBD2), is a cysteine-rich cationic antimicrobial peptide of 41 amino acids which belongs to the defensins family.
Defensin peptides are cationic peptides originally produced in various organs. They are involved in the protection against different kinds of pathogens like bacteria, fungi, and several viruses and play an important role in inflammation and wound repair.
mBD3 peptide showed antimicrobial activity against Gram-negative bacteria S.Aureus and S.pyogenes and against Gram-positive bacteria like certain strains of P.Aeruginosa (MIC of 8 µg/mL) and E.coli (MIC of 16 µg/mL). Antimicrobial activity has also been demonstrated against C.Albicans.
The in vivo and in vitro efficiency of mBD3 against viruses like influenza was also shown. mBD3 can be interesting for therapeutic use.

Myelin Basic Protein (MBP)
MBP-B (84-102) DRB1*15:01 is a short part of the myelin basic peptide. Myelin basic protein is one of the major protein found in myelin.
MBP-B (84-102) DRB1*15:01
MBP-B (84-102) DRB1*15:01 is used to stimulate immune response and T cell activity. MBP-B (84-102) DRB1*15:01 is also considered as a reference positive control in binding affinity with DRB1*15:01 molecules.

Selective blocker of Kv1.4

Blocker of voltage-gated sodium channels and T-type Cav

Chromogranin A (Human, 286-301 Amide) is a protein that belongs to the class of peptides. It is a major component of the chromaffin granules in the adrenal medulla and in neuroendocrine cells in various parts of the brain. There are two types of chromogranin A, which have 286-301 amino acids. Chromogranin A is an activator for G-protein coupled receptors, ion channels, and ligands. This protein has been used as a research tool in Cell Biology and as an inhibitor in Pharmacology.

Azido-dPEG® 11-amine is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Azido-dPEG® 11-amine is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Oxytocin is a peptide hormone that is produced by the hypothalamus and released by the pituitary gland. It is used to induce labor, control postpartum bleeding and stimulate milk production. Oxytocin also plays a role in sexual arousal, social recognition, and trust. It has been shown to have an inhibitory effect on many types of ion channels, including those found in the heart, central nervous system, and blood vessels. Oxytocin binds to receptors that are found throughout the body and brain. The receptor for oxytocin is known as OXT. This receptor belongs to the G-protein coupled receptor family of receptors. Oxytocin was first isolated from sheep serum in 1906 by Henry Dale and Charles Robert Harington. It was later synthesized in 1953 by Vincent du Vigneaud. This product has disulfide bonds between Cys1-Cys6.

Bis-ACV is a synthetic compound that has the ability to act as a carbon source for filamentous fungi. It can also be used to regulate the expression of genes and enzymes in filamentous fungi. Bis-ACV has been shown to increase the production of cytosolic calcium, thereby stimulating enzyme activities in various organisms. It is an oligosaccharide with a molecular weight of 548 Daltons and contains two acetyl groups, which are attached to glucose residues on the same side of the molecule. The biological sample was purified by HPLC and the subunits were identified by mass spectrometry. The sequence analysis revealed that Bis-ACV is composed of repeating units that have the structure of N-acetylglucosamine linked via alpha (1->4) glycosidic bonds.

Cl-Ac-(OH)Leu-Ala-Gly-NH₂ is a peptide with a molecular weight of 736.2 Da. It is an inhibitor of the enzyme protein kinase C (PKC). Cl-Ac-(OH)Leu-Ala-Gly-NH₂ has been shown to activate PKC by binding to specific domains in the enzyme, which leads to the phosphorylation and activation of PKC's regulatory subunits. This peptide can be used as a research tool in studies involving PKC and also as an antibody carrier for Western blotting and immunohistochemistry.

m-dPEG®24-MAL is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®24-MAL is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

MOCAc-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg is a peptide with ion channel activity. It is a potent activator of potassium channels and has been used in research as a tool for studying ion channel function. MOCAc is not an inhibitor of voltage sensitive sodium channels but does inhibit calcium currents. MOCAc also has been shown to be a ligand for the nicotinic acetylcholine receptor and is able to bind to the beta subunit of this receptor. This peptide binds to the alpha subunit of the calcium channel, leading to inhibition of calcium currents and activation of potassium channels.

Azido-dPEG®36-Alcohol is a PEG polymer categorised as monofunctional (OH-PEG-X). Used as a linker, azido-dPEG®36-Alcohol is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.

Amino-dPEG®12-ODMT is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®12-ODMT is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Bz-Arg-AMC is a fluorescent probe that binds to the nicotinic acetylcholine receptor (nAChR) in the presence of calcium ions and emits light when excited by ultraviolet light. It can be used to study the activation of nAChRs, as well as their interactions with other proteins such as peptides. Bz-Arg-AMC has a molecular weight of 551.9 g/mol, with a purity of > 98% and an optical purity of > 99%. This product can be used for research purposes only, not for diagnostic or therapeutic purposes.

Met-Met is a dipeptide that is synthesized from the amino acids methionine and methyltetrahydrofolate. It is used in the synthesis of peptides and biochemicals, as well as in pharmacological treatments for diseases including bacterial infections. Met-Met has significant interactions with dopamine, catechol-o-methyltransferase, and energy metabolism. The enzyme catechol-o-methyltransferase catalyzes the conversion of dopamine to 3,4-dihydroxyphenylacetic acid (DOPAC), which may lead to a decrease in dopamine levels. Met-Met also inhibits the metabolism of catecholamines, leading to an increase in cellular levels of catecholamines such as dopamine and norepinephrine. This inhibition may be responsible for metabolic disorders such as obesity or low body mass index (BMI)

Azido-dPEG®4-NHS ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Azido-dPEG®4-NHS ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Amylin is a peptide that belongs to the group of activators. It has been shown to be an inhibitor of ion channels, and has also been demonstrated to activate cell signaling pathways. Amylin can be used as a research tool for studying protein interactions, receptor ligands, and pharmacology. Amylin can be used in antibody production or as a high-purity reagent for life science or cell biology applications.

Boc-Leu-Gly-Arg-AMC is a peptide that binds to the receptor for N-methyl-D-aspartate (NMDA) and inhibits the ion channel. It has been used as a research tool to study NMDA receptor interactions, as well as in cell biology and pharmacology. Boc-Leu-Gly-Arg-AMC is a high purity, ionic analog of glutamate that binds to the NMDA receptor without activating it, thereby inhibiting ion flow through the channel. This inhibition can be reversed by adding excess glutamate or glycine. The binding of this compound to the NMDA receptor has been shown to block activation of voltage gated calcium channels and reduce neuronal excitation, which may provide an alternative therapeutic strategy for controlling seizures or other neurological disorders.

2-NBDG is a fluorescent dye that exhibits high affinity for nucleic acid and protein. It has been used as an inhibitor of protein interactions, activator of ligands, and research tool in the study of ion channels. 2-NBDG has also been used as an antibody to identify receptors, and can be used to measure the concentration of proteins, lipids, and carbohydrates. 2-NBDG is listed by CAS No. 186689-07-6.

Dnp-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg is a peptide that has been shown to be an inhibitor of protein interactions. It has been shown to activate the G protein and inhibit the enzyme phospholipase C, which may provide a potential treatment for Alzheimer's Disease. Dnp-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg also has a high purity and is used as a research tool in life science.

FRETS-25Gln is a peptide that can be used as a research tool in the fields of pharmacology and protein interactions. FRETS-25Gln binds to ion channels and activates them, which makes it useful for researching ligand-receptor interactions. The peptide has been shown to bind to the receptor P2X7 and activate the receptor, which may be useful for treating various diseases including arthritis and cancer. FRETS-25Gln also binds to the receptor P2Y1 and inhibits its activity, which may be useful for studying how activation of this receptor leads to increased vascular permeability.

Carboxyl-dPEG®4-(m-dPEG®24)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Carboxyl-dPEG®4-(m-dPEG®24)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

(Z-Leu-Leu-NHCH2)2CO is a research tool that activates the receptor. It is a ligand which binds to the receptor and can be used as an inhibitor of ion channels or as a reagent for protein interactions. The molecular weight is 584.8 g/mol and the chemical formula is C10H16N4O3. (Z-Leu-Leu-NHCH2)2CO has been shown to bind to antibodies, ion channels, and cell biology. This product has high purity and can be used in pharmacology, peptides, and life science research.

Bz-DL-Arg-pNA • HCl [DL-BAPA] is a trypsin and trypsin-like protease substrate. It is used as a tool in biochemical studies to investigate the degradation of proteins by these enzymes. Bz-DL-Arg-pNA • HCl [DL-BAPA] is also used as an experimental model for diseases that affect enzyme activity, such as rheumatoid arthritis and multiple sclerosis.

MAL-dPEG®6-NHS Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. MAL-dPEG®6-NHS Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Cyclo(Thr-Pro) is a flavonol glycoside that has been shown to have neuroprotective activity. Cyclo(Thr-Pro) binds to the mitochondrial membrane potential, which is important in the regulation of the cell's life and death. Cyclo(Thr-Pro) has also been shown to inhibit tumor growth and induce apoptosis in cancer cells. Cyclo(Thr-Pro) has been shown to be reactive with gamma-aminobutyric acid (GABA), an inhibitor of neurotransmitter release from neurons, which may contribute to its anti-inflammatory properties. Cyclo(Thr-Pro) is found in the genus Fusarium, and its natural compounds profile includes caffeine.

Des-Pro2-Bradykinin is a synthetic peptide that has been shown to be an activator of ion channels, which are proteins that regulate the flow of ions across the cell membrane. Des-Pro2-Bradykinin can also inhibit the binding of ligands (e.g., neurotransmitters) to their receptors and can activate certain G protein coupled receptors. The inhibition of these interactions may have therapeutic potential for a variety of disorders, including pain and inflammation. Des-Pro2-Bradykinin is also an inhibitor of protein interactions with antibodies or ligands and is a pharmacological tool for research in cell biology, pharmacology, and life science.

Z-Gly-Leu-NH2 is a peptide that has been shown to have specificities against the bacteria Staphylococcus. It was obtained by the synthesis of a synthetic peptide with a sequence corresponding to the amino acid sequence of casein, which is a protein found in milk. The peptide contains four amino acids and has been shown to induce cytopathic effect in staphylococci, which are rod-shaped bacteria. This peptide also has high thermostability, which means it can be heated up to 100°C for 10 minutes without changing its activity. Z-Gly-Leu-NH2 is stable at pH 5 and is resistant to proteolytic degradation by subtilisin, making it an ideal candidate for use as a food additive.

Tyrosyl-Bradykinin is a peptide that is used as a research tool. It can activate an antibody or receptor and is used in the study of protein interactions. Tyrosyl-Bradykinin has been shown to be an inhibitor of ion channels and can block the activity of ligands and receptors. This peptide has also shown pharmacological properties, such as preventing platelet aggregation and inhibiting the release of histamine from mast cells.

CoV-2 S1 (319-529) is a recombinant peptide that was derived from the CoV-2 S1 protein. It is an activator of ion channels and can be used as a research tool in pharmacology and cell biology. This peptide has been shown to bind to the Na+ channel, which is involved in the generation and propagation of nerve impulses, and to modulate its gating properties. It can also inhibit voltage-gated K+ channels, which are involved in the regulation of neuron excitability. CoV-2 S1 (319-529) is purified at > 98% purity and has a CAS number.

Amino acids 13-34 of the Parathyroid Hormone (PTH) which is a peptide hormone that is secreted from the parathyroid gland in the event of abnormal serum calcium levels and it ultimately regulates calcium and phosphate levels in the body. The PTH exerts its activity through binding to the G-protein coupled receptor type 1 PTH receptor, which activates adenylate cyclase or phospholipase C thus activating pathways involved in the mediation of bone resorption and bone formation. This product is suitable for life science applications and is available as a 0.5mg vial.

m-dPEG®36-MAL is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®36-MAL is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

A molluscan cardioexcitatory neuropeptide which has the potential to be used itn cell biology, pharmacological, and protein-protein interaction studies.

m-dPEG®12-Azide (Azido-m-dPEG®12) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®12-Azide (Azido-m-dPEG®12) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

NHS-dPEG®4-( m-dPEG®24)3-Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. NHS-dPEG®4-( m-dPEG®24)3-Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly is a peptide with the molecular formula C14H20N4O2. It is an inhibitor of protein interactions, activator of ligands and receptor, and has a CAS number of 2382-80-1. This product is used in research to study ion channels and antibodies.

4,7,8,9-Ac4-Neu5Troc(2→O)-O-C(CF3)=NPh Methyl Ester is a glycosylated peptide that is conjugated with an acetate ester. This compound is a member of the Acetyl Neu5Ac family of glycoconjugates that are found on the surface of cells and are involved in cell-cell interactions and immune responses. 4,7,8,9-Ac4-Neu5Troc(2→O)-O-C(CF3)=NPh Methyl Ester has been shown to inhibit bacterial growth by interfering with the synthesis of bacterial cell walls.

Insulin Wakayama is a recombinant human insulin that is made from genetically engineered bacteria. This product's amino acid sequence is identical to that of human insulin, and it has been shown to be active in humans. Insulin Wakayama has a high degree of purity and can be used as an immunological reagent, research tool, or pharmaceutical agent. It is also useful for studying protein interactions and the pharmacology of peptides. Insulin Wakayama has an ion channel activity and binds to receptors on the cell surface through its ligand-binding domain. This interaction activates the receptor by opening ion channels in the membrane, resulting in changes in cellular metabolism. Insulin Wakayama is not an inhibitor of tyrosine kinase enzymes such as protein tyrosine phosphatases or protein tyrosine kinases.

Gamma-Endorphin is a peptide that is used in the field of cell biology, pharmacology, and life science. It is a potent activator of opioid receptors and has been shown to be effective as an analgesic for pain relief.
This product is available as a 0.5mg vial.

Pentraxin-3 is a peptide that is an inhibitor of the activator protein. It is used in pharmacology and cell biology research to identify ligands, receptors, and ion channels. Pentraxin-3 has shown to be a useful research tool for learning about the activation of various types of ion channels, including nicotinic acetylcholine receptors, glutamate receptors, and voltage-gated potassium channels. It can also be used as an antibody to identify cells that have been activated by specific ligands or signaling pathways.