Peptides

<p>Peptide H-DLPLTFGGGTK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Ac-CSEDAIEEEGEDGVGSPRS-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>MeO-Suc-Arg-Pro-Tyr-pNA is a peptide that is used as an enzyme substrate for chymotrypsin and other proteases. It contains the amino acid sequence of methoxy (MeO), succinyl (Suc), arginine (Arg), proline (Pro), tyrosine (Tyr) and p-nitroanilide (pNA). The MeO group on the N-terminus is important for inhibiting proteolysis by chymotrypsin. This peptide is also a substrate for chymotrypsin-like enzymes.</p>

<p>Z-Arg-Arg-AMC hydrochloride salt is a versatile compound that acts as a catalyst and forms strong hydrogen bonds. It exhibits proteolytic activity and has been found to be effective in breaking down proteins. In addition, Z-Arg-Arg-AMC hydrochloride salt has been shown to possess neuroprotective properties, making it a potential candidate for the treatment of neurological disorders. It also demonstrates anthelmintic activity, which means it can be used to combat parasitic worm infections. Furthermore, this compound has antioxidant activity and can help reduce lipid peroxidation, protecting cells from oxidative damage. With its diverse range of characteristics, Z-Arg-Arg-AMC hydrochloride salt holds great promise in various research fields such as biochemistry and medicine.</p>

<p>H-Glu-Ser-OH is a tryptic fragment of the protein hormone erythropoietin that is produced by the kidneys. It is one of the major hormones involved in regulating red blood cell production. Erythropoietin stimulates the proliferation of hematopoietic cells, which are responsible for making new blood cells, and also plays an important role in wound healing. The amino acid sequence of this peptide consists of two alpha helices and four beta sheets. Structural analysis has shown that H-Glu-Ser-OH can be cleaved by proteases to produce the amino acid sequence H-Glu-Arg-OH. This fragment has been shown to have a bitter taste receptor binding activity and may play a role in casein coagulation.</p>

<p>H-Gly-Pro-Hyp-OH is a collagen gel that is extracted from bovine skin. Collagen gel is a dietary supplement that can be applied to wounds and burns to promote healing. Collagen gel contains the amino acids glycine, proline, hydroxyproline, and hypochlorous acid. It also has an anti-inflammatory cytokine called IL-10. Hydrogen bonds form between the amino acids in collagen gel to give it its strength and stability. The LC-MS/MS method was used to identify the sequences of this peptide in order to confirm its identity. Collagen gel is neutral at pH 7 and has no effect on cellular function at this pH. The carboxy terminal of collagen gel is trifluoroacetic acid which can cause liver cells to die when ingested orally or intravenously due to its toxicity.</p>

<p>H-Orn-AMC hydrochloride salt is a white solid with a melting point of about 150°C. It is used as a reactant in the manufacture of pharmaceuticals, research chemicals and other speciality chemicals. H-Orn-AMC hydrochloride salt is also an intermediate for the synthesis of complex compounds, useful as building blocks for chemical synthesis, and can be used as a reagent in analytical chemistry.</p>

<p>Please enquire for more information about rec Stem Cell Factor (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Angiotensin II is a peptide hormone that is involved in the regulation of blood pressure and fluid and electrolyte balance. It also acts as a vasoconstrictor by binding to angiotensin receptors on vascular smooth muscle cells. Angiotensin II is produced from angiotensin I by the action of renin. The high-resolution linear reformulating (HRLR) technique is used to estimate the spectrum and parameters of this molecule. This technique uses iterative methods for estimating the frequency response function and parameters for each frequency, including nonlinear ones. HRLR has been shown to be an accurate estimator with a frequency range from 0 to 10 kHz, which has not been achieved with other techniques.</p>

<p>Ghrelin is a peptide hormone that regulates appetite and has been shown to have potent anti-cachectic effects in animal models. It is thought to be an important regulator of body weight, insulin resistance, and metabolism. Ghrelin is synthesized in the stomach and released into the bloodstream when the stomach is empty. Ghrelin binds to ghrelin receptors in the hypothalamus, which stimulate growth hormone release from the pituitary gland. This hormone also binds to other cells in the hypothalamus, such as neurons that produce orexin, which may account for its effects on sleep patterns. Ghrelin has been shown to inhibit tumor growth by suppressing angiogenesis and inducing apoptosis. The molecular weight of ghrelin is 3497 Da. The sequence of ghrelin consists of 28 amino acids: Gly-Ser-Ser(octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala</p>

<p>H-Ile-Val-OH is an inhibitor of the enzyme catalysis in cancer cells. The mechanism of inhibition is likely to be competitive with respect to the substrate and reversible by addition of exogenous substrate. The IC50 values for H-Ile-Val-OH were determined in uptake assays and found to be around 100 μM. The IC50 values for H-Ile-Val-OH were also determined in x-ray diffraction data and found to be around 10 μM. H-Ile-Val-OH has been shown to inhibit squamous carcinoma cell growth, which may be due to its ability to inhibit protein synthesis.</p>

<p>Glutamate is a nonessential amino acid that is an important neurotransmitter in the central nervous system. It is found in many foods and can be synthesized by the body from other amino acids. Glutamate is also an excitatory neurotransmitter that binds to glutamate receptors, causing depolarization of the postsynaptic cell. This leads to increased intracellular calcium levels and eventually to neuronal death. Glutamate can be taken up by cells through both facilitated diffusion and active transport and converted into glutamine by glutaminase. The uptake of glutamate into cells may have clinical relevance in diseases such as hepatic steatosis, schizophrenia, or Alzheimer's disease.<br>Glu(Gln-OH)-OH (HGG) is a synthetic compound that has been shown to inhibit enzymes involved in the shikimate pathway, which converts chorismate into aromatic amino acids such as phenylalanine, tyrosine, and tryptophan. HGG has been</p>

<p>Ac-Ala-Ser-Thr-Asp-AMC is a versatile building block that can be used as an intermediate in organic synthesis, a reagent, or a speciality chemical. It is also a useful scaffold for drug discovery and development. Ac-Ala-Ser-Thr-Asp-AMC has been shown to be an effective inhibitor of phosphodiesterase 3 (PDE3) and cyclic nucleotide phosphodiesterases (PDEs).</p>

<p>Please enquire for more information about Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-gamma-carboxy-Glu-OH is a synthetic peptide with the amino acid sequence H-gamma-Carboxy-Glu. It is a glp-1 analogue and its function is to regulate glucose homeostasis. The protein has been shown to have antiapoptotic effects in human osteosarcoma cells. H-gamma-carboxy-Glu-OH has also been shown to regulate mitochondrial membrane potential, which is required for cell signaling pathways and calcium binding. H-gamma-carboxy-Glu-OH's receptor molecule is known as the GPCR, which plays an important role in the regulation of cell signaling pathways and calcium binding. H gamma carboxy Glu OH is a cyclic peptide that contains disulfide bonds. This compound has the basic structure of an alpha helix, which consists of many turns of amino acids bonded together by hydrogen bonds between individual amino acids</p>

<p>Neuropeptide W-23 (human) is an antibody that recognizes the neuropeptide receptor, specifically the Neuropeptide Y receptor 1. The antibody binds to the Npy1 receptor and inhibits its activity. Neuropeptide W-23 (human) can be used as a research tool in cell biology and pharmacology studies.</p>

<p>Gluten Exorphin B5 H-Tyr-Gly-Gly-Trp-Leu-OH is a synthetic opioid peptide that has been shown in animal models to reduce food intake and body weight. This peptide is an analog of the endogenous opioid peptides Met-enkephalin and Leu-enkephalin, which have been implicated in the regulation of food intake and energy expenditure. Gluten exorphin B5 H-Tyr-Gly-Gly-Trp-Leu-OH binds to the μ opioid receptor, which is involved in drug safety. It also binds to the prolactin receptor, which plays a role in drug absorption and distribution.</p>

<p>H-Ser-Asp-OH is a peptide that is the product of the prokaryotic gene, mycobacterium avium. It has been shown to inhibit the translation of mRNA into protein in mycobacteria. H-Ser-Asp-OH also has an anti-inflammatory effect on human cells by inhibiting the synthesis of prostaglandins. This peptide also has antiviral properties and can be used as a treatment for chronic kidney disease (CKD) and hepatitis C. The drug is not effective against HIV infection or hepatitis B virus, however, because it does not inhibit reverse transcriptase or bind to viral DNA.</p>

<p>Fluorescent substrate for angiotensin-converting enzyme 2</p>

<p>H-Glu[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2 is a peptide that is used as a targeting agent for tumor imaging. It has been shown to be an effective imaging agent for tumors by binding to the RGD sequence in the extracellular matrix of the tumor. This peptide can be derivatized with fluorochromes and other functional groups for use as a contrast agent or as a labeling reagent. H-Glu[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2 has also been shown to inhibit angiogenesis and induce apoptosis, which may be due to its ability to bind to integrin receptors on endothelial cells and block their proliferation.</p>

<p>This resin is for use in combinatorial chemistry.<br>TentaGel is a gelatinous resin and an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. Particle size 130 µm; capacity: 0.2-0.35 meq/g<br>Substitution Functional Group: -O-CH2-CH2-NH2</p>

<p>CATH-2 is a monoclonal antibody that inhibits the enterotoxin activity of E. coli, which is mediated by several strains of the bacteria. CATH-2 has been shown to be effective against enteritidis, an E. coli strain that causes food poisoning. It is not active against other strains of E. coli or Salmonella species and does not have any antibiotic effects. CATH-2 also has immunomodulatory effects and boosts chemokines such as MCP-3 and IL-8, which are chemokine receptors expressed in intestinal epithelial cells that may contribute to its anti-inflammatory properties.</p>

<p>Please enquire for more information about Cys-Ala-Thr-Lys-Val-Asn(NGA2)-Phe-Thr-Glu-Ala-Gln-Lys-Ala-Ala-Leu-Asp-Val including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>AF488 DBCO is a water-soluble, green-fluorescent probe for copper-less detection of azide-tagged biomolecules.  This probe is water-soluble and its fluorescence is pH independent over a wide pH range. The brightness and photostability of blue dyes are best suited to direct imaging of low-abundance targets.</p>

<p>Please enquire for more information about AF488 NHS Ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Somatostatin-28 is the 28 amino acid isoform of somatostatin and has similar activity to the 14 amino acid isoform. While the 14 amino acid form mainly acts in the brain, somatostatin-28 mainly operates in the gastrointestinal tract. Somatostatin is a peptide hormone that is widely expressed throughout the body for example in the gastrointestinal (GI) tract, hypothalamus, pancreas and the central nervous system. It has been found to inhibit pituitary growth hormone release as well as endocrine, pancreatic and GI secretions. In the central nervous system somatostatin plays a role in neurotransmission modification and it has also demonstrated to be effective against a number of cancers such as squamous carcinoma.</p>

<p>Fmoc-D-Leu-Wang Resin (100-200 mesh) is a research tool that is an activator, ligand, and receptor. It is used in the study of cell biology, antibody production, ion channels, and protein interactions. Fmoc-D-Leu-Wang Resin (100-200 mesh) can be used to make peptides or as a pharmacological inhibitor. This product is high purity and has CAS No.</p>

<p>A synthetic scorpion toxin, sourced from the Scorpion, Buthus martensi which has the following disulfide bonds: Cys8-Cys29, Cys14-Cys34, and Cys18-Cys36. This product is available in the trifluoroacetate salt form.<br>One-Letter-Code: FGLIDVKCFA SSECWTACKK VTGSGQGKCQ NNQCRCY</p>

<p>Peptide H-DCP-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Serum Amyloid A protein is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>H-Pro-Ile-OH is an amino acid that is found in the mitochondria of cells. It is a prodrug that binds to angiotensin and blocks its conversion to angiotensin II, which has been shown to have blood pressure lowering effects. H-Pro-Ile-OH has been shown to be a competitive inhibitor of oligopeptidase, with a half maximal inhibitory concentration (IC50) of 0.5 mM, and has also been shown to have antihypertensive properties.</p>

<p>Modified HIV TAT Sequence 49-57 for Click Chemistry. Product available as a trifluoroacetate salt</p>

<p>Please enquire for more information about rec IL-2 (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Lys-Lys-Lys-Asp-Lys-Val-Lys-Lys-Gly-Gly-Pro-Gly-Ser-Glu-Cys-Ala-Glu-Trp-Ala-Trp-Gly-Pro-Cys-Thr-Pro-Ser-Ser-Lys-Asp-Cys-Gly-Val-Gly-Phe-Arg-Glu-Gly-Thr-Cys-Gly-Ala-Gln-Thr-Gln-Arg-Ile-Arg-Cys-Arg-Val-Pro-Cys-Asn-Trp-Lys-Lys-Glu-Phe-Gly-Ala-Asp-Cys-Lys-Tyr-Lys-Phe-Glu-Asn-Trp-Gly-Ala-Cys-Asp-Gly-Gly-Thr-Gly-Thr-Lys-Val-Arg-Gln-Gly-Thr-Leu-Lys-Lys-Ala-Arg-Tyr-Asn-Ala-Gln-Cys-Gln-Glu-Thr-Ile-Arg-Val-Thr-Lys-Pro-Cys-Thr-Pro-Lys-Thr-Lys-Ala-Lys-Ala-Lys-Ala-Lys-Lys-Gly-Lys-Gly-Lys-Asp (Disulfide bonds between Cys15-Cys39, Cys23-Cys48, Cys30-Cys52, Cys62-Cys94, and Cys72-Cys104)</p>

<p>HsTX1 is a peptide toxin obtained from the venom of the scorpion Heterometrus spinnifer. It blocks potassium channels and inhibits the activity of Kv1.3 channels, which are responsible for neuronal repolarization and firing. This peptide is also a blocker of voltage-gated sodium channels, but has no effect on calcium channels. HsTX1 is used in medical research as a tool to study ion channel function.</p>

<p>This synthetic peptide is a hydrophobic RGD Fibronectin Peptide which enhances cell attachment and adhesion. This is due to it containing the Arg-Gly-Asp (RGD) sequence, is a highly conserved integrin recognition sequence within fibronectin. As a result it can promote the adhesion of cells to fibronectin, a protein found in the extracellular matrix and also promotes adhesin of cells to collagen and laminin.<br>One-Letter Formula: Ac-GrGDSPASSKGGGGSrLLLLLLr-Amide</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CALCRL antibody, catalog no. 70R-6003</p>

<p>Body Protecting Compound (BPC) 157 is a pentadecapeptide gut peptide with free radical scavenging activity.  As a gastric juice pentadecapeptide fragment, BPC 157 stimulates nitric oxide synthase generation, offering significant gastric cytoprotection. It has been shown to heal lesions in experimental models of bowel disease, Unlike many other peptides, BPC 157 effectively acts without a carrier, notably aiding in muscle healing, such as in the treatment of gastrocnemius muscle complex injuries.  BPC 157 is also an anti-inflammatory agent that has been shown to have clinical relevance in patients with congestive heart failure. BPC 157 has been shown to inhibit inflammation by blocking the production of proinflammatory mediators such as prostaglandins and leukotrienes. It also suppresses the production of proinflammatory cytokines such as tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). BPC 157 also downregulates genes that are involved in liver fibrosis, which may account for its efficacy in patients with liver cirrhosis. BPC 157 increases the production of hepatocyte growth factors (HGFs), which stimulate cell proliferation and promote tissue repair. It also upregulates genes involved in wound healing. Additionally, BPC 157 displays antianxiety and antidepressant effects. At the cellular level, it fosters proliferation, migration, and tube formation in human umbilical vein endothelial cells by activating ERK1/2 phosphorylation.</p>

<p>H-Phe-Ile-Arg-Gly-Gly-Met-Tyr-Glu-Gly-Lys-Lys is a peptide that has biological activity. It is a member of the class of Biologically Active Peptides, which are biochemicals that have been shown to have cardioprotective effects. This peptide was found to reduce cardiac injury and dysfunction in animal models of myocardial infarction.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of TRPM4 antibody, catalog no. 70R-5157</p>

<p>A synthetic AT2 Blocking peptide for use as a blocking control in assays to test for specificity of AT2 antibody, catalog no. 70R-AR006</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of CBP tag antibody, catalog no. 70R-12226</p>

<p>Dnp-Pro-Cha-Abu-Cys(Me)-His-Ala-Lys(N-Me-Abz)-NH2 is a peptide that has shown to be a potent inhibitor of MMP-1. It may also inhibit other proteases such as collagenase, stromelysin and cathepsins. Dnp-Pro-Cha-Abu-Cys(Me)-His-Ala-Lys(N-Me)-NH2 has a fluorogenic property, which makes it useful for high throughput screening of protease inhibitors. This peptide can be used in the development of new drugs for the treatment and prevention of various diseases such as cancer, cardiovascular disease and arthritis.</p>

<p>Please enquire for more information about Nesfatin-1 (mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ac-Tyr-Val-Nle-Gly-His-D-Phe-Arg-Trp-Asp-Arg-Phe-Gly-NH2 is a peptide that is a melanocortin receptor agonist. It has been shown to have biochemically active properties and can be used as a research tool in the study of peptides and their receptors.</p>

<p>Please enquire for more information about Angiotensin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Suc-Gly-Pro-Leu-Gly-Pro-AMC (SGLP) is a synthetic substrate that is hydrolyzed by proteases and has been used as a model substrate in protease studies. It has been shown to be cleaved by a number of enzymes, including chymotrypsin, trypsin, elastase, and cathepsin D. The hydrolysis products are sucrose glycolate, glycerol phosphate, leucine amino acid ester, and proline amino acid ester. SGLP has been shown to have low bioavailability in human liver cells and heart tissue. Studies have also shown that SGLP can stimulate the production of myelocytic cells in vitro. This activity may be due to its ability to act as an immunomodulator or by targeting tissue enzyme activities.</p>

<p>Dansyl-Gly-Cys-Val-Leu-Ser-OH is an α subunit of the enzyme farnesyl diphosphate synthase. Dansyl-Gly-Cys-Val-Leu-Ser-OH is a substrate for this enzyme, which catalyzes the conversion of prenyl pyrophosphates to farnesyl pyrophosphate. The biological function of this peptide is not well understood, but it may be involved in cholesterol synthesis or cellular signaling. This peptide binds to cell membranes and has been shown to have a fluorescent property. Dansyl-Gly-Cys-Val-Leu-Ser OH can also bind to peptides and proteins, including the protein receptor for the HIV virus (CD4).</p>

<p>IsoDTB (Isotopically labeled Desthoibiotin Azide) probes take advantage of the mass shift of stable heavy isotope labels (SHLs) to enable mass-independent chemical proteomics platform that helps to address unique challenges of the proteome characterization. In this approach a unique isotopic signature is embedded exclusively into the peptides and it serves as a computationally recognizable full-scan MS reporter. By using desthiobiotin, these probes circumvented the need to use cleavable linkers for peptide elution and thus simplifies the chemoproteomic protocol, while allowing quantification of the proteome. IsoTDB pack contains 2 mg of light (IsoDTB-L) and heave (IsoDTB) probe.</p>

<p>Biotinylated RGD peptide</p>