Modulateurs d'enzymes
Les modulateurs d'enzymes sont des composés qui peuvent augmenter ou inhiber l'activité des enzymes, régulant ainsi la vitesse des réactions biochimiques. Ces modulateurs jouent un rôle essentiel dans le contrôle des voies métaboliques, de la signalisation cellulaire et de divers processus physiologiques. Les modulateurs d'enzymes sont largement utilisés dans la recherche et le développement de médicaments pour étudier les fonctions enzymatiques et développer des agents thérapeutiques. Chez CymitQuimica, nous proposons une gamme complète de modulateurs d'enzymes de haute qualité pour soutenir vos recherches sur la régulation enzymatique et la découverte de médicaments.
Sous-catégories appartenant à la catégorie "Modulateurs d'enzymes"
643 produits trouvés pour "Modulateurs d'enzymes".
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Surfen
CAS :Small molecule antagonist of heparan sulfate that binds to glycosaminoglycans electrostatically. Surfen neutralised anti-coagulant activity of unfractionated and low molecular weight heparins, inhibited enzymatic sulfation and degradation reactions. Surfen also blocked signalling and cell adhesion to fibronectin that was triggered by heparan sulphate.Formule :C21H22Cl2N6ODegré de pureté :Min. 95%Masse moléculaire :445.34 g/molRapamycin-13C,d3 (contains d0) - Technical Grade
CAS :Produit contrôléBinds to FK506 binding proteins (FKBPs) to form a complex that inhibits mammalian targets of rapamycin (mTOR). Blocks p70 S6 kinase activation by interleukin-2 and thereby inhibits proliferation of T cells. Induces differentiation of human pluripotent stem cells (hPSCs) to mesendoderm and blood progenitor cells.Formule :C50CH76D3NO13Degré de pureté :Min. 95%Masse moléculaire :918.18 g/molAcetildenafil
CAS :Synthetic phosphodiesterase inhibitor
Formule :C25H34N6O3Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :466.58 g/molOzagrel HCl - Bio-X ™
CAS :Ozagrel is an antiplatelet agent that is also a thromboxane A2 synthetase inhibitor. It is used for the treatment of bronchial asthma and cerebral ischemia. It blocks platelet aggregation and reduces hypersensitivity of bronchial muscles.Formule :C13H12N2O2·HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :264.71 g/molBMS 777607
CAS :A potent Met kinase inhibitor (IC50 = 3.9 nM). Also inhibits Axl, Ron, and Tyro-3 (IC50 = 1.1, 1.8 and 4.3 nM, respectively). Anti-proliferative in Met-driven tumors in vitro and in vivo. Induces polyploidy in breast cancer cells and thereby chemoresistance.Formule :C25H19ClF2N4O4Degré de pureté :Min. 95%Masse moléculaire :512.10629MLN 0905
CAS :Inhibitor of Polo-like kinase 1Formule :C24H25F3N6SDegré de pureté :Min. 95%Masse moléculaire :486.56 g/molPemetrexed - Bio-X ™
CAS :Pemetrexed is a chemotherapy drug that belongs to the class of drugs called folate antimetabolites. It is used for the treatment of various cancers such as non-small cell lung cancer and pleural mesothelioma. Pemetrexed targets the enzymes thymidylate synthase, dihydrofolate reductase and glycinamide ribonucleotide formyltransferase. The drug works by inhibiting those enzymes so that the formation of DNA and RNA is prevented.Formule :C20H21N5O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :427.41 g/molConcanamycin A
CAS :Inhibitor of vacuolar ATP-ases
Formule :C46H75NO14Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :866.09 g/molSpirapril hydrochloride
CAS :Spirapril hydrochloride is an antihypertensive agent, which is a synthetic pharmaceutical compound designed to treat high blood pressure. The compound is derived from laboratory synthesis aimed at modulating the renin-angiotensin-aldosterone system. Its mode of action involves the inhibition of angiotensin-converting enzyme (ACE), which is crucial for the conversion of angiotensin I to the vasoconstrictor peptide angiotensin II. Angiotensin II is responsible for the constriction of blood vessels and an increase in blood pressure. By inhibiting this enzyme, Spirapril hydrochloride effectively reduces vascular resistance and lowers blood pressure.Formule :C22H30N2O5S2•HClDegré de pureté :Min. 95%Masse moléculaire :503.08 g/molAS 2863619
CAS :Cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor
Formule :C16H14Cl2N8ODegré de pureté :Min. 95%Masse moléculaire :405.24 g/molLapatinib ditosylate monohydrate
CAS :Inhibitor of EGFR (ErbB1) and HER2 (ErbB2) receptor tyrosine kinases. Used for sensitization of HER2-overexpressing cancer cells to radiation as well as chemotherapy to tamoxifen- and trastuzumab-resistant cell lines. The compound blocks signalling via Akt and mitogen-activated protein kinase (MAPK) pathways leading to reduced cell survival. In trastuzumab resistant cancer cells, it inhibits HER2 phosphorylation, prevents receptor ubiquitination and causes accumulation of inactive HER2 dimers on the cell surface.Formule :C29H26ClFN4O4S•(C7H8O3S)2•H2ODegré de pureté :Min. 95%Masse moléculaire :943.48 g/molGI 254023X
CAS :Inhibitor of ADAM10 metalloproteaseFormule :C21H33N3O4Degré de pureté :Min. 95%Masse moléculaire :391.5 g/molCCT 241533 hydrochloride
CAS :Potent and specific inhibitor of checkpoint kinase CHK2 with IC50 of 3 nM. CCT 241533 binds to the ATP pocket of CHK2 and shows minimal cross-reactivity against related kinases. CCT 241533 blocked the activity of CHK2 and impaired DNA repair in response to DNA damage in human tumoral cell lines. The compound did not potentiate genotoxicity of several genotoxic compounds but it did potentiate the cytotoxicity of a PARP inhibitor olaparib.
Formule :C23H27FN4O4•HClDegré de pureté :Min. 95%Masse moléculaire :478.94 g/molZanubrutinib
CAS :Inhibitor of Bruton's tyrosine kinase (BTK)Formule :C27H29N5O3Degré de pureté :Min. 95%Masse moléculaire :471.55 g/molTolcapone - Bio-X ™
CAS :Produit contrôléTolcapone is a catechol-O-methyltransferase (COMT) inhibitor that is used as adjunct therapy to manage symptoms of Parkinson’s disease. Although its precise mechanism is unknown, it is thought to be an inhibitor of COMT and allows for a greater reduction in the symptoms of Parkinson’s.Formule :C14H11NO5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :273.24 g/molErlotinib base
CAS :Tyrosine kinase inhibitor; affects EGFR receptor; pancreatic cancer treatmentFormule :C22H23N3O4Degré de pureté :Min. 99 Area-%Couleur et forme :PowderMasse moléculaire :393.44 g/molLGX 818
CAS :Inhibitor of B-Raf mutant (V600E); anti-neoplasticFormule :C22H27ClFN7O4SDegré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :540.01 g/molTPPB
CAS :TPPB is a small molecule inhibitor, which is synthetically derived for targeted biochemical studies. It functions by selectively modulating G-protein-coupled receptor (GPCR) signaling pathways through the inhibition of specific protein-protein interactions. This mode of action makes TPPB an insightful tool for dissecting the complex mechanisms by which G-proteins relay extracellular signals to intracellular responses.
Formule :C27H30F3N3O3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :501.54 g/molLifirafenib
CAS :Lifirafenib is a targeted anticancer therapy, which is a small molecule inhibitor sourced through pharmaceutical development processes. Its mode of action involves the selective inhibition of the RAF kinase family, including B-RAF, which plays a critical role in the MAPK/ERK signaling pathway. By targeting these kinases, Lifirafenib effectively disrupts the aberrant signaling that contributes to tumor growth and survival in certain cancers with mutations such as BRAF V600E.
Formule :C25H17F3N4O3Degré de pureté :Min. 95%Masse moléculaire :478.42 g/molAtorvastatin sodium
CAS :HMG-CoA reductase antagonist
Formule :C33H35FN2O5•NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :581.63 g/mol
