CAS: 1110813-31-4 - dacomitinib

Formula: C₂₄H₂₅ClFN₅O₂

InChI: InChI=1S/C24H25ClFN5O2/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31/h5-8,12-15H,2-4,9-11H2,1H3,(H,30,32)(H,27,28,29)/b6-5+

InChI key: InChIKey=LVXJQMNHJWSHET-AATRIKPKSA-N

SMILES: O=C(C=CCN1CCCCC1)NC2=CC=3C(=NC=NC3NC4=CC=C(F)C(Cl)=C4)C=C2OC

Sinonimi:

• (2E)-N-(4-((3-Chloro-4-Fluorophenyl)Amino)-7-Methoxy-6-Quinazolinyl)-4-(1-Piperidinyl)-2-Butenamide
• (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-Methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide
• 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-, (2E)-
• Pf 00299804
• Pf 299804
• Pf-00299804-03
• Pf-299
• Pf299804

Dacomitinib

CAS: 1110813-31-4

• Formula: C₂₄H₂₇ClFN₅O₃
• Peso molecolare: 487.95

Dacomitinib

CAS: 1110813-31-4

• Formula: C₂₄H₂₅ClFN₅O₂
• Peso molecolare: 469.95

Dacomitinib-d10

CAS: 1110813-31-4

• Formula: C₂₄H₁₅D₁₀ClFN₅O₂
• Colore e forma: Pale Yellow Solid
• Peso molecolare: 480.01

Dacomitinib

CAS: 1110813-31-4

Dacomitinib (PF299)(PF299804; PF-00299804) is a highly selective, orally bioavailable small-molecule inhibitor of the HER family …

• Formula: C₂₄H₂₅ClFN₅O₂
• Purezza: 100%
• Colore e forma: Solid
• Peso molecolare: 469.94

Dacomitinib-13C-d3

CAS: 1110813-31-4

• Formula: C₂₃₁₃CH₂₂D₃ClFN₅O₂
• Peso molecolare: 473.96

Dacomitinib

CAS: 1110813-31-4

Applications Dacomitinib is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth …

• Formula: C₂₄H₂₅ClFN₅O₂
• Colore e forma: White to Pale Yellow Solid
• Peso molecolare: 469.94

Dacomitinib

CAS: 1110813-31-4

Pan-EGFR inhibitor (HER1, HER2 and HER4); antineoplastic

• Formula: C₂₄H₂₅ClFN₅O₂
• Purezza: Min. 98 Area-%
• Colore e forma: Powder
• Peso molecolare: 469.95 g/mol