CAS 1177-87-3

Acetato di desametasone

Descrizione:

Acetato di desametasone è un corticosteroide sintetico con proprietà anti-infiammatorie e immunosoppressive. È un derivato della dexametasona, caratterizzato dall'aggiunta di un gruppo acetato, che ne migliora la solubilità e la biodisponibilità. Questo composto viene tipicamente somministrato per iniezione o come formulazione orale ed è utilizzato per trattare una varietà di condizioni, tra cui allergie, disturbi autoimmuni e alcuni tipi di cancro. Acetato di desametasone agisce inibendo il rilascio di mediatori infiammatori e modulando la risposta immunitaria. Ha una vita media relativamente lunga rispetto ad altri corticosteroidi, consentendo una somministrazione meno frequente. La sostanza è nota per la sua potenza e efficacia, ma può anche portare a effetti collaterali come l'aumento dei livelli di zucchero nel sangue, aumento di peso e possibile soppressione della ghiandola surrenale con l'uso prolungato. Come con tutti i corticosteroidi, un attento monitoraggio è essenziale per mitigare gli effetti avversi e garantire l'efficacia terapeutica.

Formula: C₂₄H₃₁FO₆

InChI: InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1

InChI key: InChIKey=AKUJBENLRBOFTD-RPRRAYFGSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](F)([C@]4(C)C(CC3)=CC(=O)C=C4)[C@@H](O)C1)[H])(C[C@@H](C)[C@@]2(C(COC(C)=O)=O)O)[H]

Sinonimi:

• (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• (11Beta,16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Acetate
• (11β,16α)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
• (16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• (8Xi,11Beta,14Xi,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• 16α-Methyl-9α-fluoroprednisolone 21-acetate
• Dalalone DP
• Dalalone LA
• Decadron LA
• Decadronal
• Dectancyl
• Dex-Cortidelt acetate
• Dexa-Cortisyl
• Dexamethasone Acetate
• Dexamethasone-17-acetate
• Dexamethasoneacetate
• Fortecortin
• Fortecortin (crystal suspension)
• NSC 39471
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-

Dexamethasone 21-Acetate

CAS: 1177-87-3

Formula: C₂₄H₃₁FO₆

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 434.50

Ref: 3B-D3628

DEXAMETHASONE ACETATE RS

CAS: 1177-87-3

DEXAMETHASONE ACETATE RS

Formula: C₂₄H₃₁FO₆

Peso molecolare: 434.4977

Ref: 41-ICRS0268

DEXAMETHASONE ACETATE CRS

CAS: 1177-87-3

DEXAMETHASONE ACETATE CRS

Ref: 41-D0710000

DEXAMETHASONE ACETATE FOR PEAK IDENTIFICATION CRS

CAS: 1177-87-3

DEXAMETHASONE ACETATE FOR PEAK IDENTIFICATION CRS

Formula: C₂₄H₃₁FO₆

Colore e forma: Crystalline Powder. Whitish. Powder.

Peso molecolare: 434.4977

Ref: 41-Y0001842

Dexamethasone Acetate

CAS: 1177-87-3

Halogenated derivatives of adrenal cortical hormones

Formula: C₂₄H₃₁FO₆

Colore e forma: White Powder

Peso molecolare: 434.21047

Ref: 45-1176506

Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-

CAS: 1177-87-3

Formula: C₂₄H₃₁FO₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 434.4977

Ref: IN-DA00HE12

Dexamethasone acetate

CAS: 1177-87-3

Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.

Formula: C₂₄H₃₁FO₆

Purezza: 99.22% - 99.65%

Colore e forma: White Or Almost White Crystalline Powder

Peso molecolare: 434.50

Ref: TM-T0947

Dexamethasone acetate

CAS: 1177-87-3

Dexamethasone acetate

Purezza: ≥98%

Peso molecolare: 434.5g/mol

Ref: 54-BUP18470

Dexamethasone 21-acetate, USP grade

CAS: 1177-87-3

Formula: C₂₄H₃₁FO₆

Purezza: (HPLC) 97.0 - 102.0 %

Colore e forma: White to off-white crystalline powder

Peso molecolare: 434.50

Ref: 7W-GP9188

Dexamethasone Acetate (Dexamethasone EP Impurity G, Betamethasone Acetate EP Impurity B)

CAS: 1177-87-3

Formula: C₂₄H₃₁FO₆

Colore e forma: White To Off-White Solid

Peso molecolare: 434.50

Ref: 4Z-D-161001

Dexamethasone Acetate

CAS: 1177-87-3

Dexamethasone Acetate

Purezza: 98%

Peso molecolare: 434.5g/mol

Ref: 54-PC109193

Dexamethasone 21-acetate

CAS: 1177-87-3

Formula: C₂₄H₃₁FO₆

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 434.50

Ref: 7W-GP5107

Dexamethasone 21-acetate

Prodotto controllato

CAS: 1177-87-3

Formula: C₂₄H₃₁FO₆

Colore e forma: Neat

Peso molecolare: 434.50

Ref: 04-C12170410

Dexamethasone acetate

CAS: 1177-87-3

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 434.210466932

Ref: 10-F987610

Dexamethasone Acetate

Prodotto controllato

CAS: 1177-87-3

Formula: C₂₄H₃₁FO₆

Colore e forma: Neat

Peso molecolare: 434.50

Ref: 86-MM0445.00

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

Prodotto controllato

CAS: 105102-22-5, 1177-87-3, 124-94-7, 13609-67-1, 14484-47-0, 1524-88-5, 2135-17-3, 2152-44-5, 25122-46-7, 25122-57-0, 3093-35-4, 33564-31-7, 356-12-7, 378-44-9, 3801-06-7, 3870-07-3, 426-13-1, 4419-39-0, 50-02-2, 50-03-3, 50-04-4, 50-23-7, 50-24-8, 51022-69-6, 51333-22-3, 514-36-3, 53-06-5, 5534-09-8, 5593-20-4, 57524-89-7, 66734-13-2, 67-78-7, 73771-04-7, 76-25-5, 80474-14-2, 83-43-2, 987-24-6

Colore e forma: Mixture

Ref: 04-A50000094ME

Dexamethasone Acetate-13C3 (Dexamethasone EP Impurity G-13C3, Betamethasone Acetate EP Impurity B-13C3)

CAS: 1177-87-3

Formula: C₂₁₁₃C₃H₃₁FO₆

Peso molecolare: 437.48

Ref: 4Z-D-161008

21-O-Acetyl Dexamethasone

Prodotto controllato

CAS: 1177-87-3

Impurity Betamethasone Acetate EP Impurity B
Applications 21-O-Acetyl Dexamethasone (Betamethasone Acetate EP Impurity B) is a protected Dexamethasone, a glucocorticoid anti-inflammatory agent.
References Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009), Rodgers, A., et al.: Chem. Res. Toxicol., 23, 724 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Formula: C₂₄H₃₁FO₆

Colore e forma: White

Peso molecolare: 434.50

Ref: TR-A168480

21-O-Acetyl Dexamethasone-d5

Prodotto controllato

CAS: 1177-87-3

Applications Isotope labelled intermediate in the synthesis of Dexamethasone (D298800), a glucocorticoid anti-inflammatory agent.
References Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009), Rodgers, A., et al.: Chem. Res. Toxicol., 23, 724 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Formula: C₂₄D₅H₂₆FO₆

Colore e forma: Neat

Peso molecolare: 439.53

Ref: TR-A168482

21-O-Acetyl dexamethasone

Prodotto controllato

CAS: 1177-87-3

21-O-Acetyl dexamethasone is a synthetic glucocorticoid that acts as a potent anti-inflammatory and immunosuppressive agent. It is used in the treatment of a wide range of conditions, including allergic reactions, skin disorders, and inflammatory bowel disease. The biological properties of this drug have been studied using an experimental model in rats. 21-O-Acetyl dexamethasone was found to be more effective than dexamethasone acetate in reducing allergic symptoms. The surface methodology has also been studied for the detection of this drug. This method is based on the reaction mechanism between the drug and matrix effect to produce fluorescent compounds that can be detected by ultraviolet (UV) light.

Formula: C₂₄H₃₁FO₆

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 434.50 g/mol

Ref: 3D-FA17017