CAS: 121584-18-7 - Valspodar

Formula: C₆₃H₁₁₁N₁₁O₁₂

InChI: InChI=1/C63H111N11O12/c1-26-27-28-41(16)53(76)52-57(80)67-49(38(10)11)61(84)68(19)33-48(75)69(20)44(29-34(2)3)56(79)66-50(39(12)13)62(85)70(21)45(30-35(4)5)55(78)64-42(17)54(77)65-43(18)58(81)71(22)46(31-36(6)7)59(82)72(23)47(32-37(8)9)60(83)73(24)51(40(14)15)63(86)74(52)25/h26-27,34-47,49-52H,28-33H2,1-25H3,(H,64,78)(H,65,77)(H,66,79)(H,67,80)/b27-26+/t41-,42+,43-,44+,45+,46+,47+,49+,50+,51+,52+/m1/s1

Sinonimi:

• Valspodar [USAN:INN]
• Sdz psc 833
• 3'-Keto-bmt(1)-val(2)-cyclosporin A
• Cyclo(((2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoyl)-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl)
• Cyclosporin D, 6-((2S,4R,6E)-4-methyl-2-methylamino)-3-oxo-6-octenoic acid)-
• Psc 833
• Unii-Q7Zp55Kf3X
• Cyclosporin A, 6-((R-(E))-6,7-didehydro-N,4-dimethyl-3-oxo-L-2-aminooctanoic acid)-7-L-valine-
• (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-1,4,7,10,12,15,19,25,28-nonamethyl-3,21,30-tris(1-methylethyl)-33-[(2R,4E)-2-methylhex-4-enoyl]-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone

Cyclosporin A, 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-

CAS: 121584-18-7

• Formula: C₆₃H₁₁₁N₁₁O₁₂
• Purezza: 98%
• Colore e forma: Solid
• Peso molecolare: 1214.6219

Valspodar

CAS: 121584-18-7

Valspodar (PSC 833) is a specific P-glycoprotein inhibitor and MDR regulator often used as a …

• Formula: C₆₃H₁₁₁N₁₁O₁₂
• Purezza: 100% - 95%
• Colore e forma: Solid
• Peso molecolare: 1214.62

Valspodar

CAS: 121584-18-7

• Formula: C₆₃H₁₁₁N₁₁O₁₂
• Peso molecolare: 1214.65

Valspodar

CAS: 121584-18-7

Applications Antineoplastic adjunct (chemosensitizer). References Boesch, D., et al.: exp. Cell Res., 196, 26 (1991), …

• Formula: C₆₃H₁₁₁N₁₁O₁₂
• Colore e forma: Neat
• Peso molecolare: 1214.62

Valspodar

CAS: 121584-18-7

P-glycoprotein (MDR1) inhibitor; non-immunosuppressive cyclosporin A analog

• Formula: C₆₃H₁₁₁N₁₁O₁₂
• Purezza: Min. 98 Area-%
• Colore e forma: Powder
• Peso molecolare: 1,214.62 g/mol