CAS 356-12-7

Fluocinonide

Descrizione:

Fluocinonide è un corticosteroide sintetico utilizzato principalmente per le sue proprietà anti-infiammatorie e immunosoppressive, rendendolo efficace nel trattamento di varie condizioni della pelle come eczema, psoriasi e dermatite. È classificato come un corticosteroide topico potente, il che significa che è progettato per essere applicato direttamente sulla pelle. La struttura chimica di Fluocinonide include uno scheletro steroideo fluorurato, che ne aumenta la potenza e l'efficacia rispetto ai corticosteroidi non fluorurati. Di solito appare come una polvere cristallina bianca o bianco sporco ed è scarsamente solubile in acqua ma solubile in solventi organici. Fluocinonide agisce inibendo il rilascio di mediatori infiammatori e riducendo la proliferazione delle cellule della pelle, alleviando così sintomi come arrossamento, prurito e gonfiore. A causa della sua potenza, è importante utilizzare Fluocinonide sotto supervisione medica per evitare potenziali effetti collaterali, come assottigliamento della pelle o assorbimento sistemico, specialmente con un uso prolungato. Come con tutti i farmaci, è necessario seguire le linee guida appropriate per il dosaggio e l'applicazione per garantire sicurezza ed efficacia.

Formula: C₂₆H₃₂F₂O₇

InChI: InChI=1/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1

InChI key: InChIKey=WJOHZNCJWYWUJD-IUGZLZTKSA-N

SMILES: C(COC(C)=O)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)(C)O2)[H])([C@]4([C@](F)([C@@H](O)C3)[C@]5(C)C([C@@H](F)C4)=CC(=O)C=C5)[H])[H]

Sinonimi:

• (6α,11β,16α)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
• 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregna-1,4-diene-3,20-dione deriv.
• Biscosal
• Dermaplus
• Flucetonide
• Flucinar
• Fluocinolide
• Fluocinolide acetate
• Fluocinolone acetonide 21-acetate
• Fluocinolone acetonide acetate
• Fluocinonid
• Fluocinonide
• Fluocinonido
• Lidex
• Lidex E
• Metosyn
• Nsc 101791
• Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, 21-acetate
• Straderm
• Topsym
• Topsymin
• Topsyn
• Topsyne
• Vanos
• 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS,12S)-4b,12-difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl acetate
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11β,16α)-
• 2-(4b,12-difluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl)-2-oxoethyl acetate
• Fluocinonideacetate
• Lonide
• Fluocinolone Acetonide EP Impurity M
• FLUOCINOMIDE
• Fluocinonide Acetonide
• Fluocinonide USP/EP/BP
• Fluorocarbon acetate
• lidexe
• fluocinolideacetate
• Gelisyn
• 1,4-PREGNADIEN-6-ALPHA, 9-ALPHA-DIFLUORO-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE 21-ACETATE
• Lidemol
• Fluocinolone Acetonide Impurity 13 (Fluocinolone Acetonide EP Impurity M）(Fluocinonide)
• Cortalar
• pregna-1,4-diene-3,20-dione, 6-alpha, 9-difluoro-11-beta,16-alpha,17,21-tetrahy droxy-, cyclic 17-acetal with acetone, 21-acetate flucinar fluocinolide fluocinolide acetate fluocinolone acetonide 21-acetate fluocinolone acetonide acetate fluocinonide lidex e Fluocinonide acetate 21-Acatyloxy-6,9-diflulro-11-hydroxy-16,17-[(1-methyl-ethylidene)bis(oxy)]pregna-1,4-di-ene-3,20-dione
• droxy-,cyclic17-acetalwithacetone,21-acetate
• Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, 21-acetate (7CI, 8CI)
• Fluocinoide acetonide
• Fluocinonide, Micronized
• Fluocinonide Solution, 100ppm
• 2-chloroethoxy(diphenyl)phosphine
• FLUOCINONIDE ACETONIDE 21-ACETATE
• Fluoxetine acetate
• Fluocinonide (100 mg)
• fluocinoloneacetonideacetate
• Fluocinonide RS
• pregna-1,4-diene-3,20-dione,6-alpha,9-difluoro-11-beta,16-alpha,17,21-tetrahy
• FLUOCINONIDE,MICRONIZED,USP

Fluocinolone Acetonide EP Impurity M

CAS: 356-12-7

Formula: C₂₆H₃₂F₂O₇

Peso molecolare: 494.5

Ref: ST-EA-CP-F56024

Fluocinonide

CAS: 356-12-7

Fluocinonide

Formula: C₂₆H₃₂F₂O₇

Purezza: 98.1%

Colore e forma: White

Peso molecolare: 494.21161

Ref: 47-489

Fluocinonide

CAS: 356-12-7

Halogenated derivatives of adrenal cortical hormones

Formula: C₂₆H₃₂F₂O₇

Colore e forma: White Cream Powder

Peso molecolare: 494.21161

Ref: 45-1276001

Fluocinonide

CAS: 356-12-7

Fluocinonide

Purezza: ≥98%

Peso molecolare: 494.52g/mol

Ref: 54-BUP15757

Fluocinonide (Fluocinolone Acetonide EP Impurity M)

CAS: 356-12-7

Formula: C₂₆H₃₂F₂O₇

Colore e forma: White To Off-White Solid

Peso molecolare: 494.53

Ref: 4Z-F-271

Fluocinonide, micronised

CAS: 356-12-7

Formula: C₂₆H₃₂F₂O₇

Purezza: ≤ 1.0%

Colore e forma: White powder

Peso molecolare: 494.52

Ref: 7W-GP3657

Fluocinonide

Prodotto controllato

CAS: 356-12-7

Formula: C₂₆H₃₂F₂O₇

Colore e forma: Neat

Peso molecolare: 494.52

Ref: 04-C13729000

Fluocinonide

CAS: 356-12-7

Colore e forma: Neat

Ref: 86-MM3001.00

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

Prodotto controllato

CAS: 105102-22-5, 1177-87-3, 124-94-7, 13609-67-1, 14484-47-0, 1524-88-5, 2135-17-3, 2152-44-5, 25122-46-7, 25122-57-0, 3093-35-4, 33564-31-7, 356-12-7, 378-44-9, 3801-06-7, 3870-07-3, 426-13-1, 4419-39-0, 50-02-2, 50-03-3, 50-04-4, 50-23-7, 50-24-8, 51022-69-6, 51333-22-3, 514-36-3, 53-06-5, 5534-09-8, 5593-20-4, 57524-89-7, 66734-13-2, 67-78-7, 73771-04-7, 76-25-5, 80474-14-2, 83-43-2, 987-24-6

Colore e forma: Mixture

Ref: 04-A50000094ME

Fluocinonide

CAS: 356-12-7

Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.

Formula: C₂₆H₃₂F₂O₇

Purezza: 98.33% - 99.70%

Colore e forma: Solid

Peso molecolare: 494.52

Ref: TM-T6502

Fluocinonide RS

CAS: 356-12-7

Colore e forma: White

Ref: 2K-1132000021

Fluocinolone Acetonide Acetate

CAS: 356-12-7

Applications Glucocorticoid; anti-inflammatory.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Brunmair, B., et al.: J. Pharmacol. Exp. Therap., 311, 109 (2004), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),

Formula: C₂₆H₃₂F₂O₇

Colore e forma: White To Off-White

Peso molecolare: 494.52

Ref: TR-F455805

Fluocinonide

CAS: 356-12-7

Fluocinonide is a synthetic corticosteroid that inhibits the production of inflammatory mediators and has anti-inflammatory effects. It is used to treat mild to moderate eczema, psoriasis, and other skin disorders. Fluocinonide is also used topically to relieve eye irritation caused by seasonal allergies or infections. This drug has minimal toxicity and does not cause major side effects in the gastrointestinal tract. Fluocinonide is a biocompatible polymer with antimicrobial properties. It binds to bacterial cell walls and disrupts their structure, causing them to rupture. The reaction solution can be used for wastewater treatment as it is able to remove organic matter from water, including bacteria and viruses.

Formula: C₂₆H₃₂F₂O₇

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 494.54 g/mol

Ref: 3D-FF08245