CAS 3801-06-7

Acetato di fluorometolone

Descrizione:

Acetato di fluorometolone è un corticosteroide sintetico utilizzato principalmente in formulazioni oftalmiche per le sue proprietà anti-infiammatorie e immunosoppressive. È caratterizzato dalla sua capacità di ridurre l'infiammazione e alleviare i sintomi associati a varie condizioni oculari, come la congiuntivite allergica e l'infiammazione post-operatoria. Il composto presenta una struttura steroidea fluorurata, che ne aumenta la potenza e riduce gli effetti collaterali sistemici rispetto ai corticosteroidi non fluorurati. Acetato di fluorometolone viene tipicamente somministrato come soluzione per colliri, consentendo un trattamento localizzato con un'assorbimento sistemico minimo. Il suo meccanismo d'azione implica l'inibizione dei mediatori infiammatori e la modulazione delle risposte immunitarie. La sostanza è generalmente ben tollerata, ma gli effetti collaterali potenziali possono includere un aumento della pressione intraoculare e la formazione di cataratte con l'uso prolungato. Come con qualsiasi corticosteroide, un attento monitoraggio è essenziale per mitigare i rischi associati alla terapia a lungo termine. In generale, Acetato di fluorometolone è un agente terapeutico prezioso nella gestione dell'infiammazione oculare.

Formula: C₂₄H₃₁FO₅

InChI: InChI=1/C24H31FO5/c1-13-10-19-17-7-9-23(14(2)26,30-15(3)27)22(17,5)12-20(29)24(19,25)21(4)8-6-16(28)11-18(13)21/h6,8,11,13,17,19-20,29H,7,9-10,12H2,1-5H3/t13-,17-,19-,20-,21-,22-,23-,24-/m0/s1

InChI key: InChIKey=YRFXGQHBPBMFHW-SBTZIJSASA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@@](OC(C)=O)(C(C)=O)CC3)[H])(C[C@H](C)C=4[C@]2(C)C=CC(=O)C4)[H]

Sinonimi:

• (6Alpha,11Beta)-9-Fluoro-11,17-Dihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione
• (6Alpha,11Beta)-9-Fluoro-11-Hydroxy-6-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Acetate
• (6α,11β)-17-(Acetyloxy)-9-fluoro-11-hydroxy-6-methylpregna-1,4-diene-3,20-dione
• 6α-Methyl-9α-fluoro-17-acetoxy-21-deoxyprednisolone
• 6α-Methyl-9α-fluoro-21-desoxyprednisolone-17-acetate
• 9-Fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate
• Ai3-52814
• Eflone
• Flarex
• Fluorometholone 17-acetate
• Nsc 47438
• Oxylone acetate
• Pregna-1,4-diene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-6-methyl-, (6alpha,11beta)-
• Pregna-1,4-diene-3,20-dione, 17-(acetyloxy)-9-fluoro-11-hydroxy-6-methyl-, (6α,11β)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17-dihydroxy-6α-methyl-, 17-acetate
• Tobrasone
• U 17,323
• Unii-9I50C3I3Ok
• FLUROMETHOLONE ACETATE
• fluorometholone acetate
• Nolpitantium
• 17-(Acetyloxy)-9-fluoro-11β-hydroxy-6α-methylpregna-1,4-diene-3,20-dione
• Eflone USP/EP/BP
• FLUOROMETHOLONE ACETATE (200 MG)
• 9-fluoro-11β,17-dihydroxy-6α-methylpregna-1,4-diene-3,20-dione 17-acetate
• FLUOROMETHALONE ACETATE
• 9-fluoro-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione 17-acetate

Fluorometholone Acetate

CAS: 3801-06-7

Halogenated derivatives of adrenal cortical hormones

Formula: C₂₄H₃₁FO₅

Colore e forma: White Powder

Peso molecolare: 418.21555

Ref: 45-1278109

Eflone

CAS: 3801-06-7

Formula: C₂₄H₃₁FO₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 418.4983

Ref: IN-DA00BXNQ

Fluorometholone Acetate

CAS: 3801-06-7

Fluorometholone Acetate

Purezza: ≥98%

Peso molecolare: 418.5g/mol

Ref: 54-BUP11720

Fluorometholone acetate

Prodotto controllato

CAS: 3801-06-7

Formula: C₂₄H₃₁FO₅

Colore e forma: Neat

Peso molecolare: 418.50

Ref: 04-C13793600

Fluorometholone Acetate

CAS: 3801-06-7

Colore e forma: Neat

Ref: 86-MM0870.01

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

Prodotto controllato

CAS: 105102-22-5, 1177-87-3, 124-94-7, 13609-67-1, 14484-47-0, 1524-88-5, 2135-17-3, 2152-44-5, 25122-46-7, 25122-57-0, 3093-35-4, 33564-31-7, 356-12-7, 378-44-9, 3801-06-7, 3870-07-3, 426-13-1, 4419-39-0, 50-02-2, 50-03-3, 50-04-4, 50-23-7, 50-24-8, 51022-69-6, 51333-22-3, 514-36-3, 53-06-5, 5534-09-8, 5593-20-4, 57524-89-7, 66734-13-2, 67-78-7, 73771-04-7, 76-25-5, 80474-14-2, 83-43-2, 987-24-6

Colore e forma: Mixture

Ref: 04-A50000094ME

Fluorometholone Acetate

CAS: 3801-06-7

Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.

Formula: C₂₄H₃₁FO₅

Purezza: 99.76%

Colore e forma: Solid

Peso molecolare: 418.50

Ref: TM-T6503

Fluorometholone Acetate

Prodotto controllato

CAS: 3801-06-7

Applications Fluorometholone Acetate is a glucocorticoid; anti-inflammatory.
References Kupferman, A., et al.: Arch. Ophthalmol., 100, 640 (1982), Tokunaga, H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),

Formula: C₂₄H₃₁FO₅

Colore e forma: Off White To Light Yellow

Peso molecolare: 418.5

Ref: TR-F593150

Fluorometholone acetate

Prodotto controllato

CAS: 3801-06-7

Fluorometholone acetate is a fluorinated corticosteroid that is used in ophthalmology to treat eye disorders. It has been shown to reduce intraocular pressure in patients with glaucoma and other eye diseases. Fluorometholone acetate inhibits the activity of the glucocorticoid receptor, which prevents it from binding to DNA and altering gene expression. This leads to a decrease in inflammatory responses by decreasing the production of cytokines and chemokines that are involved in inflammation. Fluorometholone acetate also binds to other receptors, such as the mineralocorticoid receptor, which may lead to its use as a potential biomarker for infectious diseases.

Formula: C₂₄H₃₁FO₅

Purezza: Min. 95%

Peso molecolare: 418.5 g/mol

Ref: 3D-FF23441