CAS 4419-39-0
:Beclometasone
Descrizione:
Beclometasone è un corticosteroide sintetico utilizzato principalmente per le sue proprietà anti-infiammatorie e immunosoppressive. Viene comunemente somministrato sotto forma di inalatori, spray nasali o formulazioni topiche per trattare condizioni come asma, rinite allergica e vari disturbi della pelle. La sostanza agisce inibendo il rilascio di mediatori infiammatori, riducendo così gonfiore e irritazione nei tessuti colpiti. Beclometasone ha una biodisponibilità sistemica relativamente bassa quando inalato, il che minimizza i potenziali effetti collaterali rispetto ai corticosteroidi sistemici. La sua struttura chimica presenta uno scheletro steroideo con gruppi funzionali specifici che contribuiscono alla sua potenza e selettività per i recettori dei glucocorticoidi. Il composto è generalmente ben tollerato, sebbene l'uso a lungo termine possa portare a effetti collaterali come soppressione surrenalica o irritazione locale. Come per qualsiasi farmaco, è essenziale utilizzare Beclometasone sotto supervisione medica per garantire un dosaggio appropriato e monitorare eventuali effetti avversi.
Formula:C22H29ClO5
InChI:InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
InChI key:InChIKey=NBMKJKDGKREAPL-DVTGEIKXSA-N
SMILES:Cl[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Sinonimi:- (11β,16β)-9-Chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
- (8S,10S,11S,13S,16S)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
- 4419-39-0
- 9-Chloro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Dipropanoate
- 9-Chloro-11β,17,21-trihydroxy-16β-methyl-pregna-1,4-diene-3,20-dione
- 9-Chloro-16β-methylprednisolone
- 9α-Chloro-16β-methylprednisolone
- Beclometason
- Beclometasona
- Beclometasone
- Beclometasone 17,21-Dipropionate
- Becolvent
- Pregna-1,4-diene-3,20-dione, 9-chloro-11,17,21-trihydroxy-16-methyl-, (11β,16β)-
- Vedi altri sinonimi
Ordinare per
Purezza (%)
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100
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50
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90
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95
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100
10 prodotti.
Beclomethasone (9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione)
CAS:<p>Halogenated derivatives of adrenal cortical hormones</p>Formula:C22H29ClO5Colore e forma:White PowderPeso molecolare:408.17035Beclometasone (Beclomethasone)
CAS:Formula:C22H29ClO5Colore e forma:White To Off-White SolidPeso molecolare:408.92GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
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Colore e forma:Mixture9-Chloro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione (Beclometasone)
CAS:Prodotto controllatoFormula:C22H29ClO5Colore e forma:NeatPeso molecolare:408.92Beclometasone
CAS:<p>Beclometasone is a prototype glucocorticoid receptor agonist. It is used topically as an anti-inflammatory agent and in aerosol form for the treatment of asthma.</p>Formula:C22H29ClO5Purezza:99.41% - 99.68%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:408.92Beclomethasone
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Glucocorticoid. Used in chronic asthma and allergic rhinitis. Antiallergic, antiasthmatic (inhalant). Anti-inflammatory (topical).<br>References Malfitan, V.A., et al.: Clin. Ther., 4, 472 (1982), Rao, M., et al.: J. Asthma, 19, 21 (1982), Small, P., et al.: Ann. Allergy, 49, 127 (1982), Brogden, R.N., et al.: Drugs, 28, 99 (1984),<br></p>Formula:C22H29ClO5Colore e forma:Off-WhitePeso molecolare:408.92Beclomethasone - 98% min
CAS:Prodotto controllato<p>Beclomethasone is a synthetic glucocorticoid that has significant effects on the bronchial system. It is used for the treatment of bronchial asthma and other diseases of the airways. Beclomethasone may be administered by inhalation, orally, or topically. Beclomethasone binds to cytoplasmic receptors in target cells and inhibits phospholipases, which are enzymes that release arachidonic acid from cell membranes. This process inhibits the production of leukotrienes, prostaglandins, and thromboxanes-all compounds that have been implicated in inflammation and bronchial asthma. The pharmacokinetic profile of Beclomethasone includes a high volume of distribution and low protein binding. Beclomethasone has been shown to inhibit nuclear receptors such as PPARα and GR, which regulate gene transcription for lipid metabolism.</p>Formula:C22H29ClO5Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:408.92 g/molBeclomethasone - 95% min
CAS:Prodotto controllato<p>Beclomethasone is a synthetic glucocorticoid that has been approved for the treatment of asthma and inflammatory bowel disease. It reduces inflammation by suppressing the immune system response. Beclomethasone has also been used in clinical studies to treat bronchial, bowel disease, and natriuretic effects due to its ability to increase magnesium levels in the body. Clinical trials have shown that beclomethasone can be used as an effective therapy for asthma. This drug also has anti-inflammatory properties and may be useful in treating infectious diseases such as tuberculosis. Beclomethasone has been shown to be effective against many different types of bacteria including Mycobacterium tuberculosis and Streptococcus pneumoniae.</p>Formula:C22H29ClO5Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:408.92 g/mol
