CAS 50-03-3

Acetato di idrocortisone

Descrizione:

Acetato di idrocortisone, con il numero CAS 50-03-3, è un corticosteroide sintetico comunemente usato per le sue proprietà anti-infiammatorie e immunosoppressive. È una polvere cristallina bianca a quasi bianca che è praticamente insolubile in acqua ma solubile in solventi organici come etanolo e acetone. La sostanza è spesso utilizzata in formulazioni topiche, come creme e unguenti, per trattare varie condizioni della pelle, tra cui eczema e dermatite, così come in forme iniettabili per effetti sistemici. Acetato di idrocortisone funziona mimando gli effetti del cortisolo, un ormone naturale prodotto dalle ghiandole surrenali, riducendo così l'infiammazione e sopprimendo la risposta immunitaria. I suoi effetti farmacologici includono vasocostrizione, inibizione dell'infiltrazione dei leucociti e soppressione della produzione di citochine. Sebbene generalmente ben tollerato, gli effetti collaterali potenziali possono includere assottigliamento della pelle, irritazione locale ed effetti sistemici con uso prolungato. Un dosaggio e una somministrazione adeguati sono cruciali per minimizzare gli effetti avversi e massimizzare i benefici terapeutici.

Formula: C₂₃H₃₂O₆

InChI: InChI=1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1

InChI key: InChIKey=ALEXXDVDDISNDU-JZYPGELDSA-N

SMILES: C[C@@]12[C@]([C@]3([C@]([C@@H](O)C1)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])(CC[C@@]2(C(COC(C)=O)=O)O)[H]

Sinonimi:

• (11β)-21-(Acetyloxy)-11,17-dihydroxypregn-4-ene-3,20-dione
• 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-acetate
• 17-Hydroxycorticosterone 21-acetate
• 17α-Hydroxycorticosterone acetate
• 21-Acetate d'hydrocortisone
• 21-Acetato De Hidrocortisona
• 21-Acetoxy-11β,17-dihydroxypregn-4-en-3,20-dione
• 21-Acetoxy-11β,17-dihydroxypregn-4-ene-3,20-dione
• 21-Acetoxy-11β,17α-dihydroxypregn-4-ene-3,20-dione
• 4-Pregnene-11β,17,21-triol-3,20-dione 21-acetate
• Abbocort
• Anusol HC
• Bambicort
• Berlison F
• Biocortar
• CaldeCort
• Chemysone
• Colifoam
• Colofoam
• Cordes
• Cortacream
• Cortaid
• Cortef acetate
• Cortell
• Corticaine
• Cortifoam
• Cortisol acetate
• Cortisol, 21-acetate
• Cortril acetate
• Cortril acetate AS
• Efcolin
• HA
• Hc 45
• Hycortole acetate
• Hydrin 2
• Hydrocal
• Hydrocort acetate
• Hydrocortisat
• Hydrocortison-21-acetat
• Hydrocortisone 21-Acetate
• Hydrocortisone acetate
• Hydrocortistab
• Hydrocortone acetate
• Hydroxycorticosterone acetate
• Isopto-Hydrocortisone
• Lanacort
• Lenirit
• Nsc 741
• Pabracort
• Proctocort
• Sigmacort
• Sintotrat
• Velopural
• Wycort
• 11-beta,17-alpha-dihydroxy-21-acetoxypregesterone
• Acetate-as
• 11beta17alpha-Dihydroxy-21-acetoxypregesterone
• (8xi,9xi,11beta,14xi)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl acetate
• Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11β)-
• (11beta)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl acetate
• 21-acetoxy-4-pregnene-11b,17a-diol-3,20-dione

Hydrocortisone Acetate

CAS: 50-03-3

Formula: C₂₃H₃₂O₆

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 404.50

Ref: 3B-H0184

Hydrocortisone acetate, 97+%

CAS: 50-03-3

Hydrocortisone acetate is used to treat hemorrhoids and itching/swelling in the rectum and anus. It is used to treat certain intestinal problems (such as ulcerative colitis of the rectum and other rectal/anal inflammatory conditions). This Thermo Scientific Chemicals brand product was originally par

Formula: C₂₃H₃₂O₆

Purezza: 97+%

Colore e forma: White to cream, Powder or crystals or crystalline powder

Peso molecolare: 404.51

Ref: 02-A18089

Hydrocortisone Acetate

CAS: 50-03-3

Colore e forma: Neat

Ref: 61-FOR0187.00

HYDROCORTISONE ACETATE CRS

CAS: 50-03-3

HYDROCORTISONE ACETATE CRS

Formula: C₂₃H₃₂O₆

Colore e forma: Powder

Peso molecolare: 404.4966

Ref: 41-H1400000

HYDROCORTISONE ACETATE FOR PEAK IDENTIFICATION CRS

CAS: 50-03-3

HYDROCORTISONE ACETATE FOR PEAK IDENTIFICATION CRS

Formula: C₂₃H₃₂O₆

Colore e forma: Powder

Peso molecolare: 404.4966

Ref: 41-Y0001482

HYDROCORTISONE ACETATE RS

CAS: 50-03-3

HYDROCORTISONE ACETATE RS

Formula: C₂₃H₃₂O₆

Colore e forma: Powder

Peso molecolare: 404.4966

Ref: 41-ICRS0326

Hydrocortisone acetate

CAS: 50-03-3

Hydrocortisone acetate

Formula: C₂₃H₃₂O₆

Purezza: 98.8%

Colore e forma: White To Off-White

Peso molecolare: 404.21989

Ref: 47-584

Hydrocortisone Acetate

CAS: 50-03-3

Adrenal cortical hormones and their derivatives nesoi

Formula: C₂₃H₃₂O₆

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 404.21989

Ref: 45-1317007

Hydrocortisone Acetate

CAS: 50-03-3

Formula: C₂₃H₃₂O₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 404.4966

Ref: IN-DA003QYO

Hydrocortisone acetate

CAS: 50-03-3

Hydrocortisone acetate (Cortisol 21-acetate) is the synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive

Formula: C₂₃H₃₂O₆

Purezza: 98.89% - 99.22%

Colore e forma: White To Off-White Crystalline Powder

Peso molecolare: 404.5

Ref: TM-T1243

Hydrocortisone Acetate

CAS: 50-03-3

Hydrocortisone Acetate

Purezza: 98%

Peso molecolare: 404.5g/mol

Ref: 54-OR1029275

Hydrocortisone acetate

CAS: 50-03-3

Formula: C₂₃H₃₂O₆

Purezza: ≤ 1.0%

Colore e forma: White to almost white crystalline powder

Peso molecolare: 404.51

Ref: 7W-GA8586

Hydrocortisone EP Impurity C (Cortisone Acetate EP Impurity A, Hydrocortisone Acetate)

CAS: 50-03-3

Formula: C₂₃H₃₂O₆

Peso molecolare: 404.51

Ref: 4Z-H-103035

Hydrocortisone acetate

CAS: 50-03-3

Hydrocortisone acetate

Purezza: ≥98%

Peso molecolare: 404.5g/mol

Ref: 54-BUP19932

Hydrocortisone acetate

CAS: 50-03-3

Hydrocortisone acetate

Purezza: ≥98%

Peso molecolare: 404.5g/mol

Ref: 54-BUP19145

Hydrocortisone Acetate

CAS: 50-03-3

Colore e forma: Neat

Ref: 86-MM0187.00

Hydrocortisone acetate

Prodotto controllato

CAS: 50-03-3

Formula: C₂₃H₃₂O₆

Colore e forma: Neat

Peso molecolare: 404.50

Ref: 04-C14224020

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

Prodotto controllato

CAS: 105102-22-5, 1177-87-3, 124-94-7, 13609-67-1, 14484-47-0, 1524-88-5, 2135-17-3, 2152-44-5, 25122-46-7, 25122-57-0, 3093-35-4, 33564-31-7, 356-12-7, 378-44-9, 3801-06-7, 3870-07-3, 426-13-1, 4419-39-0, 50-02-2, 50-03-3, 50-04-4, 50-23-7, 50-24-8, 51022-69-6, 51333-22-3, 514-36-3, 53-06-5, 5534-09-8, 5593-20-4, 57524-89-7, 66734-13-2, 67-78-7, 73771-04-7, 76-25-5, 80474-14-2, 83-43-2, 987-24-6

Colore e forma: Mixture

Ref: 04-A50000094ME

Hydrocortisone Acetate RS

CAS: 50-03-3

Colore e forma: White

Ref: 2K-1122000021

Hydrocortisone EP Impurity C

CAS: 50-03-3

Formula: C₂₃H₃₂O₆

Peso molecolare: 404.5

Ref: ST-EA-CP-H9017

Prednisolone acetate EP Impurity A

CAS: 50-03-3

Formula: C₂₃H₃₂O₆

Peso molecolare: 404.5

Ref: ST-EA-CP-P212001

Hydrocortisone 21-Acetate-D3

Prodotto controllato

CAS: 50-03-3

Applications Hydrocortisone 21-Acetate-D3 is the labeled compound form of Hydrocortisone 21-Acetate (H714620) which is a glucocorticoid.
References Middleton, B., et al.: J. Biol. Chem., 256, 4827 (1981), Moore, A., et al.: Ann. Clin. Biochem., 22, 435 (1985).

Formula: C₂₃H₂₉D₃O₆

Colore e forma: Neat

Peso molecolare: 407.52

Ref: TR-H714622

Hydrocortisone 21-Acetate

Prodotto controllato

CAS: 50-03-3

Impurity Hydrocortisone EP Impurity C
Applications Hydrocortisone 21-Acetate (Hydrocortisone EP Impurity C) is a glucocorticoid.
References Middleton, B., et al.: J. Biol. Chem., 256, 4827 (1981), Moore, A., et al.: Ann. Clin. Biochem., 22, 435 (1985)

Formula: C₂₃H₃₂O₆

Colore e forma: Neat

Peso molecolare: 404.50

Ref: TR-H714620

Hydrocortisone acetate

CAS: 50-03-3

Purezza: 95.0%

Colore e forma: Solid, White powder

Peso molecolare: 404.50299072265625

Ref: 10-F091494

Hydrocortisone acetate

Prodotto controllato

CAS: 50-03-3

Hydrocortisone acetate is a synthetic corticosteroid, which is a product derived from the modification of natural adrenal cortex hormones. It functions as an anti-inflammatory and immunosuppressive agent through its interaction with glucocorticoid receptors, leading to the modulation of gene expression involved in immune and inflammatory responses. This interaction inhibits the release of pro-inflammatory mediators and reduces the permeability of capillaries, thereby diminishing inflammation and immune activity.

Formula: C₂₃H₃₂O₆

Purezza: Min. 97 Area-%

Colore e forma: Powder

Peso molecolare: 404.5 g/mol

Ref: 3D-FH32127