CAS 55-03-8

Levotiroxina sodica

Descrizione:

Levotiroxina sodica, con il numero CAS 55-03-8, è una forma sintetica dell'ormone tiroideo tiroxina (T4) utilizzata principalmente nel trattamento dell'ipotiroidismo. È una polvere cristallina bianca o bianco sporco solubile in acqua e ha una formula molecolare di C15H11I4NNaO4. La sostanza agisce aumentando il tasso metabolico dei tessuti, influenzando la sintesi proteica e regolando il metabolismo di carboidrati e grassi. Levotiroxina sodica viene tipicamente somministrato per via orale ed è caratterizzato dalla sua alta biodisponibilità e lunga emivita, consentendo una somministrazione una volta al giorno nella maggior parte dei casi. È essenziale per mantenere una crescita e uno sviluppo normali, in particolare nei bambini, e gioca un ruolo critico nel metabolismo energetico. La potenza del farmaco può essere influenzata da vari fattori, tra cui la presenza di cibo, altri farmaci e caratteristiche individuali del paziente. Come con qualsiasi farmaco, il monitoraggio dei livelli di ormone tiroideo è cruciale per garantire l'efficacia terapeutica e per evitare potenziali effetti collaterali associati a un trattamento eccessivo o insufficiente.

Formula: C₁₅H₁₁I₄NO₄·Na

InChI: InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/t12-;/m0./s1

InChI key: InChIKey=BRLSOHUOWVCKNI-YDALLXLXSA-N

SMILES: O(C1=CC(I)=C(O)C(I)=C1)C2=C(I)C=C(C[C@@H](C(O)=O)N)C=C2I.[Na]

Sinonimi:

• <span class="text-smallcaps">L</span>-Thyroxin Henning
• <span class="text-smallcaps">L</span>-Thyroxine monosodium salt
• <span class="text-smallcaps">L</span>-Thyroxine sodium
• <span class="text-smallcaps">L</span>-Thyroxine sodium salt
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)
• Berlthyrox
• Dathroid
• Droxine
• Eferox
• Elthyrone
• Elthyroxine
• Eltroxin
• Euthyrox
• Eutirox
• L-Thyroxine sodium
• L-Thyroxine sodium salt
• Laevoxin
• Letrox
• Letter
• Levaxin
• Leventa
• Levo-T
• Levolet
• Levoroxine
• Levothroid
• Levothyrox
• Levotirox
• Levotiroxina
• Levoxyl
• Monosodium thyroxine
• NSC 259940
• Novothyrox
• Oroxine
• Puran T 4
• Sodium 2-Amino-3-[4-(4-Hydroxy-3,5-Diiodophenoxy)-3,5-Diiodophenyl]Propanoate
• Sodium 4-O-(4-Hydroxy-3,5-Diiodophenyl)-3,5-Diiodo-L-Tyrosine
• Sodium <span class="text-smallcaps">L</span>-thyroxine
• Sodium levothyroxine
• Sodium thyroxin
• Sodium thyroxinate
• Sodium thyroxine
• Synthroid
• Synthroid sodium
• Synthrox
• T 4Kp
• T4 Montpellier 100
• Thevier
• Throxinique
• Thyradin
• Thyradin S
• Thyrax Duotab
• Thyrex
• Thyro 4
• Thyrosit
• Thyroxevan
• Thyroxine sodium
• Thyroxine sodium salt
• Thyroxine, monosodium salt, <span class="text-smallcaps">L</span>-
• Tiroidine
• Tirosint
• Unithroid
• tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)
• L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt
• L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1)

L-Thyroxine Sodium Salt Pentahydrate

CAS: 51-48-9, 55-03-8, 6106-07-6

Formula: C₁₅H₁₀I₄NNaO₄·5H₂O

Purezza: >98.0%(T)

Colore e forma: White to Yellow to Orange powder to crystal

Peso molecolare: 888.94

Ref: 3B-T0245

Levothyroxine sodium impurity standard

CAS: 55-03-8

Levothyroxine sodium impurity standard

Colore e forma: White To Off-White

Ref: 47-1284

L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodiumsalt

CAS: 55-03-8

Formula: C₁₅H₁₀I₄NNaO₄

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 798.8518

Ref: IN-DA00I9TF

L-Thyroxine sodium

CAS: 55-03-8

L-Thyroxine sodium

Purezza: ≥98%

Peso molecolare: 798.85g/mol

Ref: 54-BUP18449

L-Thyroxine sodium

CAS: 55-03-8

L-Thyroxine sodium (LT4 sodium), the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.

Formula: C₁₅H₁₀I₄NO₄·Na

Purezza: 98.74%

Colore e forma: Yellowish To Buff-Colored Amorphous Powder Solid

Peso molecolare: 798.85

Ref: TM-T22355

Thyroxine Sodium Salt

Prodotto controllato

CAS: 55-03-8

Stability Hygroscopic
Applications One of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976), Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988), Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996), Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997),

Formula: C₁₅H₁₀I₄NO₄·Na

Colore e forma: Neat

Peso molecolare: 798.85

Ref: TR-T425601

Levothyroxine sodium

CAS: 55-03-8

Levothyroxine sodium is a thyroid hormone that is used to treat hypothyroidism. It is also used to treat goiter and other thyroid problems. Levothyroxine sodium comes in three different forms: tablets, oral solution, and levothyroxine sodium for injection. The tablet form of levothyroxine sodium is taken by mouth once daily with or without food. Oral solution is taken by mouth twice daily (morning and evening) with or without food. Injection should be given as directed by a physician or healthcare provider. Levothyroxine sodium can interact with many drugs, especially ones that affect the heart or blood sugar levels, such as potassium supplements, diuretics, beta blockers, calcium channel blockers, erythromycin, clarithromycin and ketoconazole. Levothyroxine sodium can also interact with certain foods such as soybean flour and grapefruit juice. Levothyroxine sodium has been shown to have a linear calibration curve in vivo

Formula: C₁₅H₁₀I₄NNaO₄

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 798.85 g/mol

Ref: 3D-FL32108