CAS 71989-31-6

Fmoc-Pro-OH

Descrizione:

Fmoc-Pro-OH, o 9-fluorenilmetossicarbonile-prolina, è un amminoacido protetto comunemente usato nella sintesi di peptidi. Presenta un gruppo fluorenilmetossicarbonile (Fmoc), che funge da gruppo protettivo per la funzionalità amminica della prolina, consentendo reazioni selettive durante l'assemblaggio dei peptidi. Il gruppo Fmoc è stabile in condizioni basiche, ma può essere rimosso in condizioni acide leggere, facilitando il passaggio di deprotezione nella sintesi dei peptidi. Fmoc-Pro-OH è caratterizzato dalla sua relativamente alta solubilità in solventi organici, come dimetilformammide (DMF) e diclorometano, mentre è meno solubile in acqua. Questo composto è cruciale nella sintesi di peptidi in fase solida, dove aiuta nell'aggiunta sequenziale di amminoacidi per formare peptidi. La sua struttura include uno scheletro di prolina, che introduce proprietà conformazionali uniche a causa della sua struttura ciclica, influenzando la struttura secondaria complessiva del peptide. Il numero CAS 71989-31-6 identifica in modo univoco questo composto, garantendo una comunicazione precisa nella letteratura scientifica e nelle banche dati.

Formula: C₂₀H₁₉NO₄

InChI: InChI=1S/C20H19NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,22,23)/t18-/m0/s1

InChI key: InChIKey=ZPGDWQNBZYOZTI-SFHVURJKSA-N

SMILES: C(OC(=O)N1[C@H](C(O)=O)CCC1)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Sinonimi:

• (2S)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acid
• (2S)-1-[[(9H-Fluoren-9-yl)methoxy]carbonyl]pyrrolidine-2-carboxylic acid
• (S)-N-(9-Fluorenylmethoxycarbonyl)proline
• (S)-hidrogenopirrolidina-1,2-dicarboxilato de 1-(9H-fluoren-9-ilmetilo)
• (S)-hydrogenopyrrolidine-1,2-dicarboxylate de 1-(9H-fluorene-9-ylmethyle)
• 1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (S)-
• 1-(9H-fluoren-9-ylmethyl) hydrogen (S)-pyrrolidine-1,2-dicarboxylate
• 1-(9H-fluoren-9-ylmethyl)-(S)-hydrogenpyrrolidin-1,2-dicarboxylat
• Fluorenylmethoxycarbonylproline
• Fmoc-<span class="text-smallcaps">L</span>-Pro-OH
• Fmoc-<span class="text-smallcaps">L</span>-proline
• Fmoc-L-proline
• Fmoc-Pro-OH
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• N-(9-Fluorenylmethoxycarbonyl)-L-proline
• N-(9-Fluorenylmethoxycarbonyl)proline
• N-FMOC-<span class="text-smallcaps">L</span>-proline
• N-FMOC-L-proline
• Nsc 334294

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-proline

CAS: 71989-31-6

Formula: C₂₀H₁₉NO₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 337.38

Ref: 3B-F0298

N-Fmoc-L-proline, 98%

CAS: 71989-31-6

It is used as pharmaceutical intermediate. Fmoc method is used for the synthesis of the new polymeric support for the preparation of C-terminal peptide amides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label inform

Formula: C₂₀H₁₉NO₄

Purezza: 98%

Colore e forma: Crystals or powder or crystalline powder, White to pale cream

Peso molecolare: 337.38

Ref: 02-B21081

Fmoc-Pro-OH

CAS: 71989-31-6

M03372 - Fmoc-Pro-OH

Formula: C₂₀H₁₉NO₄

Purezza: 98%

Colore e forma: Solid, Crystalline or Powder

Peso molecolare: 337.375

Ref: 10-M03372

Fmoc-Pro-OH

CAS: 71989-31-6

Bachem ID: 4003150.

Formula: C₂₀H₁₉NO₄

Purezza: 99.8%

Colore e forma: White

Peso molecolare: 337.38

Ref: 01-4003150

Fmoc-Pro-OH

CAS: 71989-31-6

Formula: C₂₀H₁₉NO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 337.3692

Ref: IN-DA003QO0

Fmoc-L-Proline

CAS: 71989-31-6

Fmoc-L-Proline (Fmoc-Pro-OH) is a proline derivative.

Formula: C₂₀H₁₉NO₄

Purezza: 99.22%

Colore e forma: Solid

Peso molecolare: 337.37

Ref: TM-T64331

Fmoc-L-Proline, 10mM (in DMSO)

CAS: 71989-31-6

Fmoc-L-Proline, 10mM (in DMSO)

Purezza: ≥98%

Peso molecolare: 337.37g/mol

Ref: 54-BUP19106

Fmoc-Pro-OH

CAS: 71989-31-6

Formula: C₂₀H₁₉NO₄

Purezza: ≥ 99.0%

Colore e forma: White to off-white or pale yellow crystalline powder

Peso molecolare: 337.38

Ref: 7W-GM2265

FMOC-Pro-OH

CAS: 71989-31-6

FMOC-Pro-OH

Formula: C₂₀H₁₉NO₄

Purezza: 98%

Colore e forma: white to off white powder

Peso molecolare: 337.37g/mol

Ref: 54-OR54567

L-Proline-2,5,5-d3-N-FMOC

CAS: 71989-31-6

Purezza: 98 atom % D

Colore e forma: White Solid

Peso molecolare: 340.39

Ref: 3U-D7565

Fmoc-Pro-OH

CAS: 71989-31-6

Formula: C₂₀H₁₉NO₄

Peso molecolare: 337.38

Ref: 4Z-P-166009

Fmoc-Pro-OH

CAS: 71989-31-6

Fmoc-Pro-OH is a synthetic cyclic peptide with the amino acid sequence (Fmoc-Lys-Lys-Ala-Glu)n. Fmoc-Pro-OH binds to the androgen receptor and can be used as a research tool to identify other molecules that bind to the same receptor. It has been shown to inhibit the activity of ester hydrochloride, trifluoroacetic acid, and superparamagnetic iron in coordination complexes.

Formula: C₂₀H₁₉NO₄

Purezza: Min. 95 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 337.37 g/mol

Ref: 3D-FF15871

Fmoc-Pro-OH

CAS: 71989-31-6

Fmoc-Pro-OH is a peptide that contains the Fmoc protecting group. It is used in the synthesis of peptides and has been shown to be effective against microbial infections with marine sponges. The synthesis of this compound can be carried out on an on-line automated peptide synthesizer. The Fmoc protecting group is removed by treatment with trifluoroacetic acid (TFA) in dichloromethane, which leaves the side chain unprotected. This compound has a high binding affinity for the receptor site of fibrinogen and can potentially inhibit the growth of bacteria that cause bacterial infection, such as Staphylococcus aureus and Pseudomonas aeruginosa.
Fmoc-Pro-OH can also be used to synthesize other functional groups such as sulfamoyl groups or acetonitrile groups, depending on the desired outcome.

Formula: C₂₀H₁₉NO₄

Purezza: Min. 98 Area-%

Peso molecolare: 337.38 g/mol

Ref: 3D-FLP-1731-PI

FMOC-L-Proline extrapure, 99%

CAS: 71989-31-6

Formula: C₂₀H₁₉NO₄

Purezza: min. 99%

Colore e forma: White to Off white, Crystalline powder

Peso molecolare: 337.38

Ref: SR-12047

L-Proline-N-Fmoc

Prodotto controllato

CAS: 71989-31-6

Applications L-Proline-N-Fmoc is N-Fmoc protected L-Proline (P755995) which is an amino acid and precursor (with vitamin C) for collagen, the building block of the structure of tendons, ligaments, arteries, veins and muscles. It is important in wound healing.
References Bondarenko, L.B., et al.: Int. J. Peptides., 2, 1687 (2012); Rimer, T., et al.: Biomacromolecules, 13, 2110 (2012);

Formula: C₂₀H₁₉NO₄

Colore e forma: Neat

Peso molecolare: 337.37

Ref: TR-P756005

L-Proline-d3-N-Fmoc

Prodotto controllato

CAS: 71989-31-6

Applications L-Proline-d3-N-Fmoc was used to prepare potent bombesin-like peptides for GRP-receptor targeting of tumors. It was also used to synthesize tetrapeptide aldehyde inhibitors of dengue virus NS3 protease.
References Nock, B., et al.: J. Med. Chem., 48, 100 (2005); Yin, Z., et al.: Bioorg. Med. Chem. Lett., 16, 40 (2006)

Formula: C₂₀D₃H₁₆NO₄

Colore e forma: Neat

Peso molecolare: 340.39

Ref: TR-P756007