CAS 84625-61-6

Itraconazolo

Descrizione:

Itraconazolo è un agente antifungino triazolico utilizzato principalmente per trattare varie infezioni fungine, comprese quelle causate da dermatofiti, lieviti e alcuni muffe. Funziona inibendo la sintesi dell'ergosterolo, un componente essenziale delle membrane cellulari fungine, interrompendo così la loro integrità e funzione. Itraconazolo è caratterizzato dalla sua relativamente bassa solubilità in acqua, ma è più solubile in solventi organici, il che influisce sulla sua biodisponibilità. Il composto ha una formula molecolare di C35H38Cl2N8O4S e presenta una struttura complessa che include un anello triazolico. Viene tipicamente somministrato per via orale o endovenosa, con la sua farmacocinetica influenzata da fattori come l'assunzione di cibo e i livelli di pH. Itraconazolo è noto per il suo ampio spettro di attività contro vari funghi, ma può anche interagire con altri farmaci a causa dei suoi effetti sugli enzimi epatici. Gli effetti collaterali comuni possono includere disturbi gastrointestinali, elevazioni degli enzimi epatici e potenziali effetti cardiovascolari, richiedendo monitoraggio durante il trattamento.

Formula: C₃₅H₃₈Cl₂N₈O₄

InChI: InChI=1/C35H38Cl2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3/t25?,31-,35-/s2

InChI key: InChIKey=VHVPQPYKVGDNFY-WGEGMAFPNA-N

SMILES: C([C@]1(O[C@@H](COC2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)N5C(=O)N(C(CC)C)N=C5)CO1)C6=C(Cl)C=C(Cl)C=C6)N7C=NC=N7

Sinonimi:

• 2-Butan-2-Yl-4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1,2,4-Triazol-1-Yl Methyl)-1,3-Dioxolan-4-Yl]Methoxy]Phenyl]Piperazin-1-Yl]Phenyl]-1,2,4-Triazol-3-One
• 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-, rel-
• 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-
• Candistat
• Canditral
• Cladosal 100
• Fungitraxx
• Itrac
• Itraconozole
• Itralek
• Itrizole
• Oriconazole
• Orungal
• Orungamin
• Pur 1900
• R 51211
• SUBA Itraconazole
• Sempera
• Spherazole CR
• Spherazole IR
• Sporal
• Sporamelt
• Sporanox
• Sporanox IV
• Sporonox
• Traconal
• Triasporin
• cis-Itraconazole
• rel-4-[4-[4-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

Itraconazole, 98%

CAS: 84625-61-6

Itraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It?s different formulations are used to study Candida strains in murine

Formula: C₃₅H₃₈Cl₂N₈O₄

Purezza: 98%

Colore e forma: White to cream, Powder or crystalline powder

Peso molecolare: 705.64

Ref: 02-J66390

Itraconazole

CAS: 84625-61-6

Colore e forma: Neat

Ref: 61-FOR0258.00

Itraconazole 2.0 mg/ml in Dimethyl Sulfoxide

CAS: 84625-61-6

Colore e forma: Single Solution

Ref: 61-AMP0258.00-36

ITRACONAZOLE CRS

CAS: 84625-61-6

ITRACONAZOLE CRS

Formula: C₃₅H₃₈Cl₂N₈O₄

Colore e forma: White. Powder.

Peso molecolare: 705.6334

Ref: 41-I7000000

Itraconazole

CAS: 84625-61-6

Itraconazole

Formula: C₃₅H₃₈CI₂N₈O₄

Purezza: 99.7%

Colore e forma: White To Off-White

Peso molecolare: 900.11055

Ref: 47-1199

ITRACONAZOLE FOR SYSTEM SUITABILITY CRS

CAS: 84625-61-6

ITRACONAZOLE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001100

Itraconazole

CAS: 84625-61-6

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₃₅H₃₈ClN₈O₄

Colore e forma: White Powder

Peso molecolare: 669.27045

Ref: 45-1354251

Itraconazole

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 705.6334

Ref: IN-DA003R60

Itraconazole

CAS: 84625-61-6

Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.

Formula: C₃₅H₃₈Cl₂N₈O₄

Purezza: 98% - 99.90%

Colore e forma: Off-White Crystalline Solid

Peso molecolare: 705.63

Ref: TM-T1011

Itraconazole

CAS: 84625-61-6

Itraconazole

Purezza: ≥98%

Peso molecolare: 705.63g/mol

Ref: 54-BUP15992

Itraconazole-d3

CAS: 84625-61-6

Formula: C₃₅H₃₅D₃Cl₂N₈O₄

Colore e forma: Off-White Solid

Peso molecolare: 708.67

Ref: 4Z-I-032

Itraconazole-d9

CAS: 84625-61-6

Formula: C₃₅H₂₉D₉Cl₂N₈O₄

Colore e forma: Off-White Solid

Peso molecolare: 714.70

Ref: 4Z-I-036

Itraconazole Impurity 5

CAS: 1217510-38-7, 84625-61-6

Formula: C₃₄H₃₅Cl₂N₈O₄·Cl

Colore e forma: Yellow Solid

Peso molecolare: 690.61 35.45

Ref: 4Z-I-0331

Itraconazole N-Oxide

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₅

Colore e forma: White To Off-White Solid

Peso molecolare: 721.64

Ref: 4Z-I-0329

Itraconazole

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₄

Purezza: 99.0 - 101.0 % (dried basis)

Colore e forma: White or almost white powder

Peso molecolare: 705.63

Ref: 7W-GA0307

Itraconazole

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₄

Colore e forma: White To Off-White Solid

Peso molecolare: 705.64

Ref: 4Z-I-031

Itraconazole

CAS: 84625-61-6

Itraconazole

Purezza: 98%

Peso molecolare: 705.63g/mol

Ref: 54-OR1029174

Itraconazole

CAS: 84625-61-6

Colore e forma: Neat

Ref: 86-MM0258.00

Itraconazole

Prodotto controllato

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₄

Colore e forma: Neat

Peso molecolare: 705.63

Ref: 04-C14485000

Itraconazole

CAS: 84625-61-6

Formula: C₃₅H₃₈Cl₂N₈O₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 705.64

Ref: 3B-I0732