Angiogenesi
Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.
Sottocategorie di "Angiogenesi"
- BTK(158 prodotti)
- Bcr-Abl(113 prodotti)
- EGFR(598 prodotti)
- FAK(72 prodotti)
- FLT(90 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(182 prodotti)
- JAK(246 prodotti)
- PDGFR(126 prodotti)
- RAAS(90 prodotti)
- Src(81 prodotti)
- Syk(37 prodotti)
- Trombina(53 prodotti)
- VDA(2 prodotti)
- VEGFR(250 prodotti)
Mostrare 6 più sottocategorie
Trovati 2040 prodotti di "Angiogenesi"
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ON 146040
CAS:ON 146040 is an effective inhibitor of PI3K isoforms with IC50s of 14 and 20 nM for PI3Kα and PI3Kδ, respectively.Formula:C24H23N7O3SPurezza:97.39%Colore e forma:SolidPeso molecolare:489.55Tyrphostin AG 112
CAS:Tyrphostin AG 112 is an inhibitor of EGFR phosphorylation.Formula:C13H8N4OPurezza:99.14%Colore e forma:SolidPeso molecolare:236.23PDGFRα kinase inhibitor 1
CAS:PDGFRα kinase inhibitor 1 is a type II PDGFRα kinase inhibitor that inhibits both PDGFRα and PDGFRβ.Formula:C34H34N8O2Purezza:99.78%Colore e forma:SolidPeso molecolare:586.69Mutated EGFR-IN-2
CAS:Mutated EGFR-IN-2 is an inhibitor of mutant-selective EGFR.Formula:C29H35FN8O3Purezza:98%Colore e forma:SolidPeso molecolare:562.64PP2 Analog
CAS:PP2 Analog is an analog of PP2. It also acts as a protein trafficking modulator.Formula:C16H17ClN4Purezza:98%Colore e forma:SolidPeso molecolare:300.79Cyt-PTPε Inhibitor-1
CAS:Cyt-PTPε Inhibitor-1 (A Inhibitor-1) is an inhibitor of cytosolic protein tyrosine phosphatase ε.Formula:C19H20N4O2SPurezza:99.55% - 99.82%Colore e forma:SolidPeso molecolare:368.45CGP60474
CAS:CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.Formula:C18H18ClN5OPurezza:98.81%Colore e forma:SolidPeso molecolare:355.82FGFR2-IN-1
CAS:FGFR2-IN-1 is an FGFR inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used to study FGFR2-associated cancers.Formula:C22H19N3O2Purezza:98.71%Colore e forma:SolidPeso molecolare:357.41EAI001
CAS:EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.Formula:C19H15N3O2SPurezza:99.94%Colore e forma:SolidPeso molecolare:349.41ZK-304709 HCl
CAS:ZK-304709 is an oral multitarget tumor growth inhibitor with activity against cell-cycle progression and angiogenesis.Formula:C22H29ClN6O2Colore e forma:SolidPeso molecolare:444.96UniPR1331
CAS:UniPR1331 is a novel selective antagonist of the Eph-ephrin system.Formula:C35H48N2O4Colore e forma:SolidPeso molecolare:560.77BPIQ-II (hydrochloride)
CAS:BPIQ-II, a selective EGFR inhibitor with an IC50 of 8 pM, targets ATP sites and halts EGF signals inside cells.Formula:C15H11BrClN5Colore e forma:SolidPeso molecolare:376.64TYRA-200
CAS:TYRA-200 is an effective oral inhibitor of FGFR1/2/3. In both wild-type FGFR2 and FGFR2 mutant models, TYRA-200 can produce tumor regression effects in a dose-dependent manner. TYRA-200 can be used in the research of advanced or metastatic intrahepatic cholangiocarcinoma and other solid tumors driven by FGFR2.Formula:C23H24FN7O2Peso molecolare:449.48JNJ-64264681
CAS:JNJ-64264681 is a potent, orally active, selective, and irreversible covalent inhibitor of Bruton's tyrosine kinase (BTK).Formula:C27H30N6O3SPurezza:98%Colore e forma:SolidPeso molecolare:518.63RK-20448
CAS:RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2. It also inhibits BLK, Csk, Fyn, and Lyn. RK-20448 is the cis isomer of A-419259Formula:C29H34N6OColore e forma:SolidPeso molecolare:482.62Antiproliferative agent-20
CAS:Antiproliferative agent-20: potent oral anticancer drug with anti-angiogenic properties.Formula:C23H18N2O6Colore e forma:SolidPeso molecolare:418.4Atrinositol
CAS:Atrinositol improves energy homeostasis in a mouse model of pancreatic cancer.Formula:C6H15O15P3Colore e forma:SolidPeso molecolare:420.1EphB1-IN-1
CAS:EphB1-IN-1 is a potent inhibitor of EphB1, exhibiting IC50 values of 3.0 nM for EphB1 G703C, 15 nM for EphB1 T697G, and 220 nM for EphB1 WT.Formula:C16H12Cl2N4O2Colore e forma:SolidPeso molecolare:363.2Tec-IN-6
CAS:Tec-IN-6 is an inhibitor of Tec kinase, it also blocks unconventional secretion of fibroblast growth factor 2 (FGF2).Formula:C19H19N3O5Purezza:98%Colore e forma:SolidPeso molecolare:369.37EGFR/HER2-IN-12
CAS:EGFR/HER2-IN-12 (compound 14b) serves as a dual inhibitor targeting EGFR and HER2, demonstrating 81% and 51% inhibition respectively at a concentration of 10 μM. This compound exhibits minimal toxicity towards A431 and MDA-MB-361 cancer cells [1].Formula:C25H17ClN4O3SPeso molecolare:488.95SPH5030
CAS:SPH5030 is an irreversible, selective inhibitor of HER2.Formula:C31H31FN8O3Colore e forma:SolidPeso molecolare:582.63MTX-531
CAS:MTX-531 is a selective inhibitor of EGFR and PI3K with IC50 of 14.7 nM and 1.1-233 nM (PI3Kα, PI3Kβ...), respectively. It also acts as a weak agonist of PPARγ, with an EC50 of 3.4 μM in 293H cells.Formula:C22H20ClN5O2SColore e forma:SoildPeso molecolare:453.94RSH-7
CAS:RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducingFormula:C22H25FN8OPurezza:99.43%Colore e forma:SolidPeso molecolare:436.49R-932348 choline
CAS:R-932348 choline, a dual JAK/SYK inhibitor, is used potentially for treatment of dry eye disease.Formula:C28H35FN6O5SPurezza:98%Colore e forma:SolidPeso molecolare:586.68Z118332870
CAS:Z118332870 is a potent inhibitor of EGFR and BRD4.Formula:C18H18FN3O3Colore e forma:SolidPeso molecolare:343.35BCR-ABL-IN-7
CAS:BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.Formula:C19H16FN3O3SPurezza:98.28%Colore e forma:SolidPeso molecolare:385.41PF-6422899
CAS:PF-6422899 irreversibly inhibits EGFR kinase activity by binding covalently to active-site cysteine residues in the ATP binding pocket of EGFR.Formula:C20H14ClFN4O2Colore e forma:SolidPeso molecolare:396.8MJ04
CAS:MJ04 is a selective inhibitor of Janus Kinase 3 (JAK3) with an IC50 of 2.03 nM. It hinders T cell differentiation and suppresses pro-inflammatory cytokines in macrophages induced by Lipopolysaccharides. In mice, MJ04 exhibits favorable pharmacokinetic properties and promotes hair growth in a DHT-induced alopecia model in athymic mice, without notable toxicity (LD50>2 g/kg).Formula:C20H16FN5Colore e forma:SolidPeso molecolare:345.37KBP-7018 HCl
CAS:KBP-7018 Hydrochloride is a novel, tyrosine kinase-selective inhibitor with potent effects on three fibrotic kinases (c-KIT, PDGFR, and RET).Formula:C31H31ClN4O5Colore e forma:SolidPeso molecolare:575.06TG-46
CAS:TG-46 (TG46) inhibits JAK2, FLT3, RET, JAK3 and can be used to study glaucoma.Formula:C26H34N6O3SPurezza:98.82% - 99.86%Colore e forma:SolidPeso molecolare:510.65PF-06672131
CAS:PF-06672131 is a selective EGFR kinase inhibitor.Formula:C23H21ClFN5O2Colore e forma:SolidPeso molecolare:453.9Lanraplenib monosuccinate
CAS:Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Formula:C27H31N9O5Purezza:98%Colore e forma:SolidPeso molecolare:561.59NAMI-A
CAS:NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.Formula:C8H15Cl4N4ORuSPurezza:98%Colore e forma:SolidPeso molecolare:458.18Sovleplenib
CAS:Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.Formula:C24H30N6O3SPurezza:99.71%Colore e forma:SolidPeso molecolare:482.6ALK5-IN-26
CAS:ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 (IC50 ≤ 1 nM).Formula:C24H25FN8Colore e forma:SolidPeso molecolare:444.51EGFR-IN-73
CAS:EGFR-IN-73 (Compound 3f) effectively inhibits the prevalent EGFR mutation, EGFR Del19, exhibiting an IC50 value of 119 nM [1].Formula:C19H17ClFN3O4Purezza:98%Colore e forma:SolidPeso molecolare:405.81ER-27319
CAS:ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosineFormula:C20H22N2O5Purezza:98%Colore e forma:SolidPeso molecolare:370.4A-420983
CAS:A-420983 is a novel potent Lck inhibitor, exhibiting oral efficacy in animal models of delayed-type hypersensitivity and organ transplant rejection.Formula:C33H39N9O2Colore e forma:SolidPeso molecolare:593.72Mutated EGFR-IN-3
CAS:Mutated EGFR-IN-3: ATP-competitive, selective dibenzodiazepinone inhibitor for EGFR mutations, IC50 12-13 nM.Formula:C31H29FN4O2Purezza:98%Colore e forma:SolidPeso molecolare:508.59PF-719 free base
CAS:PF-719 is a potent, selective Pyk2 inhibitor with IC50 of 17 nM.Formula:C22H27F3N6OColore e forma:SolidPeso molecolare:448.48PH11
CAS:PH11, a FAK inhibitor, reactivates TRAIL apoptosis in PANC-1 cells by reducing c-FLIP and inhibiting FAK/PI3K/AKT.Formula:C22H22N6O5Colore e forma:SolidPeso molecolare:450.45SDZ281-977
CAS:SDZ 281-977 is a derivative of Lavendustin A which is the EGF receptor tyrosine kinase inhibitor.Formula:C18H20O5Purezza:99.64%Colore e forma:SolidPeso molecolare:316.35AXL-IN-13
CAS:AXL-IN-13: potent, oral AXL inhibitor, IC50=1.6nM, Kd=0.26nM, anti-cancer, inhibits EMT, cell migration & invasion.Formula:C34H41FN6O5Purezza:99.95%Colore e forma:SolidPeso molecolare:632.72ZD4190 HCl
CAS:ZD-4190, a potent VEGFR inhibitor, prevents tumour outgrowth in a model of minimal residual carcinoma in deep tissues.Formula:C19H17BrClFN6O2Purezza:98%Colore e forma:SolidPeso molecolare:495.73RTC-5
CAS:RTC-5 (TRC-382) is a phenothiazine compound that has been specifically enhanced for its potent anti-cancer properties.Formula:C24H22ClF3N2O3SPurezza:98.14%Colore e forma:SolidPeso molecolare:510.96AC710 Mesylate
CAS:AC710 Mesylate is a potent PDGFR inhibitor (Kds: 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRα and PDGFRβ).Formula:C32H46N6O7SPurezza:98%Colore e forma:SolidPeso molecolare:658.81MMPP
CAS:MMPP is a VEGFR2 inhibitor with anti-inflammatory activity, inhibits STAT3 , inhibits angiogenesis, and can be used to alleviate myocardial injury.Formula:C17H18O3Purezza:99.31% - 99.83%Colore e forma:SolidPeso molecolare:270.32FAK inhibitor 2
CAS:FAK inhibitor 2, antitumor and anti-angiogenesis activitiesis ,is a potent focal adhesion kinase (FAK) inhibitor with an IC50 of 0.07 nM .Formula:C29H33F3N8O2S2Colore e forma:SolidPeso molecolare:646.75CS12192
CAS:CS12192 enhances survival, boosts weight, and shows promise in GVHD research per patent CN112773802A.Formula:C25H23ClFN7O2Colore e forma:SolidPeso molecolare:507.95AFN941
CAS:AFN941 is a staurosporine analog, acting as a Jak3-specific inhibitor.Formula:C28H30N4O3Colore e forma:SolidPeso molecolare:470.56FLT3-IN-4
CAS:FLT3-IN-4 (FLT3 inhibitor 9u) is a potent and orally effective Fms-like tyrosine receptor kinase 3 (FLT3; IC50=7 nM) inhibitor ,for treating acute myelogenousFormula:C23H25N7O2Purezza:99.9%Colore e forma:SolidPeso molecolare:431.49RO9021
CAS:RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).Formula:C18H25N7OPurezza:99.90%Colore e forma:SolidPeso molecolare:355.44RG 14467
CAS:RG 14467 is an antagonist of epidermal growth factor-urogastrone.Formula:C14H14N2O3Colore e forma:SolidPeso molecolare:258.27(E/Z)-CP-724714
CAS:(E/Z)-CP-724714, comprising racemic mixtures of (E)-CP-724714 and (Z)-CP-724714 isomers, is a potent, selective, and orally active inhibitor of ErbB2 (HER2)[1].Formula:C27H27N5O3Purezza:98%Colore e forma:SolidPeso molecolare:469.54Cenisertib benzoate
CAS:Cenisertib benzoate is an orally bioavailable, synthetic, small-molecule multi-Aurora kinase inhibitor with potential antineoplastic activity.Formula:C31H36FN7O3Colore e forma:SolidPeso molecolare:573.66RG 14921
CAS:RG 14921 is a pyridone analog of erbstatin, epidermal growth factor (EGF) receptor tyrosine kinase, and cAMP-dependent kinase.Formula:C11H9NO3Colore e forma:SolidPeso molecolare:203.19OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Formula:C18H15N3O3SPurezza:98%Colore e forma:Dark Orange SolidPeso molecolare:353.39TOP1210
CAS:TOP1210, a narrow spectrum kinase inhibitor, potently inhibits P38α, Src, and Syk kinase activities.Formula:C45H48N8O6Colore e forma:SolidPeso molecolare:796.91DBPR112
CAS:DBPR112: oral furanopyrimidine EGFR inhibitor; IC50: 15 nM (EGFRWT), 48 nM (L858R/T790M); blocks ATP site, strong antitumor effects.Formula:C32H31N5O3Purezza:99.25%Colore e forma:SolidPeso molecolare:533.62Antiproliferative agent-34
CAS:Antiproliferative Agent-34 (Compound A14), a multitarget kinase inhibitor, demonstrates IC50 values of 177 nM for EGFR L858R/T790M and 1567 nM for EGFR WT.Formula:C27H27N7O5Purezza:98%Colore e forma:SolidPeso molecolare:529.55FGFR-IN-13
CAS:FGFR-IN-13 (compound III-30), an irreversible covalent inhibitor of the fibroblast growth factor receptor (FGFR), effectively modulates signaling through FGFR1 (IC 50 = 0.20 ± 0.02 nM) and FGFR4 (IC 50 = 0.40 ± 0.03 nM). It suppresses the expression of crucial proteins such as total-PARP and Bcl-2, while enhancing the expression of Cleaved-PARP and Bax in a dose-dependent manner. Notably, FGFR-IN-13 demonstrates considerable antitumor and oral activity [1].Formula:C23H21N5O3Peso molecolare:415.44Zotiraciclib HCl
CAS:Zotiraciclib (TG02/SB1317) is a CDK/JAK2/FLT3 inhibitor potentially treating Myc-overexpressing cancers, including glioblastoma.Formula:C23H26Cl2N4OColore e forma:SolidPeso molecolare:445.388AMG-Tie2-1
CAS:AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.Formula:C25H20F3N5O2Purezza:98.9%Colore e forma:SolidPeso molecolare:479.45Infigratinib phosphate
CAS:Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, andFormula:C26H34Cl2N7O7PPurezza:99.24% - 99.6%Colore e forma:SolidPeso molecolare:658.47AC430
CAS:AC430, a specific JAK2 inhibitor for cancer and autoimmune therapy, excels in preclinical trials with low doses. Developed by Ambit.Formula:C19H16FN5OColore e forma:SolidPeso molecolare:349.36Aminoquinuride
CAS:Surfen, or Aminoquinuride, reduces inflammation but blocks remyelination in MS mouse models and regulates murine T cell activation.Formula:C21H20N6OColore e forma:SolidPeso molecolare:372.42HKI-357 dimaleate
CAS:HKI-357 dimaleate is an irreversible dual inhibitor of EGFR and ERBB2. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.Formula:C39H37ClFN5O11Colore e forma:SolidPeso molecolare:806.2Spebrutinib besylate
CAS:Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s).Formula:C28H28FN5O6SPurezza:98%Colore e forma:SolidPeso molecolare:581.62EGFR T790M/L858R-IN-5
CAS:EGFR T790M/L858R-IN-5 (example 52) functions as a potent EGFR T790M/L858R inhibitor, demonstrating a 92.9% inhibition rate at a concentration of 0.05 μM [1].Formula:C28H31N9OPeso molecolare:509.61JAK3-IN-1
CAS:JAK3-IN-1 is an orally active, selective and potent JAK3 inhibitor for the study of immune system disorders.Formula:C26H30ClN7O2Colore e forma:SolidPeso molecolare:508.02Rogaratinib
CAS:<p>Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR).</p>Formula:C23H26N6O3SPurezza:99.54%Colore e forma:SolidPeso molecolare:466.56FGFR2-IN-2
CAS:<p>FGFR2-IN-2 is a specific FGFR2 inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used in the study of cancer and cardiovascular disease.</p>Formula:C23H22N4OPurezza:98.09%Colore e forma:SolidPeso molecolare:370.45Tarlox-TKI
CAS:Tarlox-TKI (Kinase inhibitor-1) is a pan-ErbB inhibitor, the active ingredient of Tarloxotinib, which has antitumor activity.Formula:C19H18BrClN6OPurezza:97.03%Colore e forma:SolidPeso molecolare:461.74VEGFR-2-IN-6
CAS:VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].Formula:C20H21N7O2SPurezza:99.01%Colore e forma:SolidPeso molecolare:423.49c-Fms-IN-3
CAS:c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.Formula:C23H30N6OPurezza:99.87%Colore e forma:SolidPeso molecolare:406.52LY 456236 hydrochloride
CAS:LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM.Formula:C16H16ClN3O2Purezza:99.95%Colore e forma:SolidPeso molecolare:317.77A-935142
CAS:A-935142 enhances hERG (Kv 11.1) channels, slows inactivation, promotes activation, and shortens repolarization.Formula:C18H19F3N2O2Purezza:98.97% - 99.91%Colore e forma:SolidPeso molecolare:352.35CTA 056
CAS:CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.Formula:C35H34N6OPurezza:97.22% - 97.76%Colore e forma:SolidPeso molecolare:554.68CHMFL-EGFR-202
CAS:<p>CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase (IC50s: 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases).</p>Formula:C25H24ClN7O2Purezza:99.66%Colore e forma:SolidPeso molecolare:489.96H-9 dihydrochloride
CAS:H-9 dihydrochloride: Strong PKA inhibitor, curbs 5-HT response and EGF signaling, affects pharyngeal function.Formula:C11H15Cl2N3O2SPurezza:97.3%Colore e forma:SolidPeso molecolare:324.23A 419259 trihydrochloride
CAS:A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).Formula:C29H37Cl3N6OPurezza:99.75% - 99.96%Colore e forma:SolidPeso molecolare:592Tafetinib
CAS:Tafetinib (SIM-010603) is a novel potent and orally available tyrosine kinase inhibitor with anti-angiogenic and anti-tumour activity.Formula:C24H29FN4O2Purezza:96.23%Colore e forma:SolidPeso molecolare:424.51Defactinib hydrochloride
CAS:Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.Formula:C20H22ClF3N8O3SPurezza:98.06% - 98.78%Colore e forma:SolidPeso molecolare:546.95Cloperastine fendizoate
CAS:Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).Formula:C40H38ClNO5Purezza:99.97%Colore e forma:SolidPeso molecolare:648.19SU16f
CAS:SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.Formula:C24H22N2O3Purezza:97.69%Colore e forma:SolidPeso molecolare:386.44NX-2127
CAS:NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferativeFormula:C39H45N9O5Purezza:99.07%Colore e forma:SolidPeso molecolare:719.83Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Formula:C26H27NO6Purezza:98.99%Colore e forma:SolidPeso molecolare:449.5(±)-Zanubrutinib
CAS:(±)-Zanubrutinib ((±)-BGB-3111) is a potent and orally available Bruton's tyrosine kinase (Btk) inhibitor that demonstrates superior oral bioavailability,Formula:C27H29N5O3Purezza:99.09%Colore e forma:SolidPeso molecolare:471.55PD 174265
CAS:PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.Formula:C17H15BrN4OPurezza:99.51%Colore e forma:SolidPeso molecolare:371.23TC-S 7009
CAS:TC-S 7009: Strong HIF-2α inhibitor (Kd 81 nM), weak for HIF-1α; disrupts dimerization & gene expression.Formula:C12H6ClFN4O3Purezza:99.46% - 99.71%Colore e forma:SolidPeso molecolare:308.65MBM-55
CAS:MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.Formula:C28H27FN6O2Purezza:99.83%Colore e forma:SolidPeso molecolare:498.55BMS-605541
CAS:<p>BMS-605541 is a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) kinase activity(Ki=49 nM).</p>Formula:C19H17F2N5OSPurezza:98.07%Colore e forma:SolidPeso molecolare:401.43Butyzamide
CAS:<p>Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.</p>Formula:C29H32Cl2N2O5SPurezza:99.51% - 99.83%Colore e forma:SoildPeso molecolare:591.55PP58
CAS:PP58 is an inhibitor of PDGFR, FGFR and Src family.Formula:C22H19Cl2N5O2Purezza:99.21%Colore e forma:SolidPeso molecolare:456.32(R)-Zanubrutinib
CAS:(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).Formula:C27H29N5O3Purezza:99.55%Colore e forma:SolidPeso molecolare:471.55ARN25068
CAS:ARN25068 inhibits GSK-3β, FYN, DYRK1A kinases; acts in sub-micromolar range; combats tau hyperphosphorylation.Formula:C19H18N6SPurezza:99.75%Colore e forma:SolidPeso molecolare:362.45P505-15 Acetate
CAS:<p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>Formula:C21H27N9O3Purezza:99.99%Colore e forma:SolidPeso molecolare:453.5STS-E412
CAS:STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.Formula:C15H15ClN4O2Purezza:99.01%Colore e forma:SolidPeso molecolare:318.76VEGFR-3-IN-1
CAS:VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.Formula:C29H29ClF3N7OSPurezza:99.95%Colore e forma:SolidPeso molecolare:616.1EGFR-IN-11
CAS:EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.Formula:C29H35N9O2SPurezza:99.93%Colore e forma:SolidPeso molecolare:573.71
