Angiogenesi

Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.

Sottocategorie di "Angiogenesi"

Mostrare 6 più sottocategorie

Trovati 2121 prodotti di "Angiogenesi"

Purezza (%)

100

prodotti per pagina.

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Anticancer agent 133
Compound Rh2 (Anticancer agent 133) is a cytotoxic and antimetastatic agent that induces cell cycle arrest, apoptosis, and autophagy.
Formula:C₂₄H₁₉Cl₃N₅ORh
Purezza:98%
Colore e forma:Solid
Peso molecolare:602.71
Ref: TM-T78743
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Conbercept
CAS:
- 1227158-72-6
Conbercept (KH902) is a fusion protein comprising the second immunoglobulin C-like domain of FLT1 and the third and fourth immunoglobulin C-like domains of KDR
Purezza:98%
Colore e forma:Liquid
Ref: TM-T80595
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Lyn peptide inhibitor
CAS:
- 222018-18-0
Inhibits Lyn kinase, blocks IL-5 receptor, prevents eosinophil differentiation and reduces asthma-related inflammation in mice.
Formula:C₁₁₅H₁₈₄N₃₀O₂₄
Purezza:98%
Colore e forma:Solid
Peso molecolare:2370.91
Ref: TM-TP2008
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SIAIS100
SIAIS100, a potent BCR-ABL PROTAC degrader, demonstrates a DC50 value of 2.7 nM, highlighting its efficacy.
Formula:C₄₄H₅₀ClF₂N₉O₅S
Colore e forma:Solid
Peso molecolare:890.44
Ref: TM-T75012
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JAK 3 inhibitor IV
CAS:
- 58753-54-1
JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to
Formula:C₁₆H₁₉NO
Purezza:98%
Colore e forma:Solid
Peso molecolare:241.33
Ref: TM-T2460
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AT-533
CAS:
- 908112-37-8
AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and HUVEC activities.
Formula:C₂₃H₃₀N₄O₃
Purezza:99.67%
Colore e forma:Soild
Peso molecolare:410.51
Ref: TM-T67836
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VEGFR-2-IN-36
VEGFR-2-IN-36 (compound 15) serves as a potent VEGFR-2 inhibitor, exhibiting an IC50 value of 0.067 μM, and acts as an apoptosis inducer with demonstrated
Formula:C₂₄H₂₃N₇O₅
Purezza:98%
Colore e forma:Solid
Peso molecolare:489.48
Ref: TM-T79403
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SNIPER(ABL)-039
CAS:
- 2222354-29-0
SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of
Formula:C₅₄H₆₈ClN₁₁O₉S₂
Purezza:98%
Colore e forma:Solid
Peso molecolare:1114.77
Ref: TM-T18690
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Tephrosin
CAS:
- 76-80-2
Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors, has potent antitumor activities.
Formula:C₂₃H₂₂O₇
Purezza:98%
Colore e forma:Solid
Peso molecolare:410.42
Ref: TM-T13126
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Tyrosinase-IN-16
CAS:
- 126651-85-2
Tyrosinase-IN-16 inhibited tyrosinase.
Formula:C₈H₆BrN₃S
Purezza:99.94%
Colore e forma:Solid
Peso molecolare:256.12
Ref: TM-T67939
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Bevasiranib
CAS:
- 959961-96-7
Bevasiranib is a siRNA targeting VEGF production, key in choroidal neo-vascularization and wet AMD.
Colore e forma:Solid
Ref: TM-T75156
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Wu-5
CAS:
- 2630378-05-9
Wu-5 is a potent USP10 inhibitor that inhibits FLT3 and AMPK pathways, promoting the breakdown of FLT3-ITD and inducing apoptosis.
Formula:C₁₅H₁₃NO₇S
Purezza:99.65%
Colore e forma:Soild
Peso molecolare:351.33
Ref: TM-T77763
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Varlitinib
CAS:
- 845272-21-1
Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively.
Formula:C₂₂H₁₉ClN₆O₂S
Purezza:99.7%
Colore e forma:Solid
Peso molecolare:466.94
Ref: TM-T6719
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Laprituximab
CAS:
- 1622327-38-1
Laprituximab (J2898A) is a humanized anti-EGFR antibody used for synthesizing ADC compound Laprituximab emtansine.
Purezza:>95%
Colore e forma:Liquid
Ref: TM-T77050
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SJ10542
CAS:
- 2789678-92-6
SJ10542: potent JAK2/3-targeting PG-PROTAC; DC50s: JAK2 - 14 nM, JAK3 - 11 nM, JAK2-fusion ALL - 24 nM; CRBN recruiter.
Formula:C₄₁H₄₆N₁₂O₅S
Colore e forma:Solid
Peso molecolare:818.95
Ref: TM-T74429
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BCR-ABL-IN-3
CAS:
- 2240191-12-0
BCR-ABL-IN-3 irreversibly inhibits Bcr-Abl with <100 nM IC50, showing significant anti-cancer effects.
Formula:C₂₀H₁₇ClF₂N₄O₃S
Colore e forma:Solid
Peso molecolare:466.89
Ref: TM-T39732
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SC209
CAS:
- 1977557-86-0
SC209, a STRO-002 metabolite from patent WO2021247798, synthesizes anti-EGFR ADCs.
Formula:C₂₇H₄₄N₄O₄
Colore e forma:Solid
Peso molecolare:488.66
Ref: TM-T74367
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SJF 1521
CAS:
- 2230821-40-4
SJF 1521 is an EGFR degrader belonging to the PROTAC class that selectively degrades EGFR while preserving HER2.
Formula:C₅₇H₆₁ClFN₇O₉S
Purezza:99.20%
Colore e forma:Solid
Peso molecolare:1074.65
Ref: TM-T36244
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Coprelotamab
CAS:
- 2348469-84-9
<p>Coprelotamab (GB-221) is an IgG-κ monoclonal antibody that targets EGFR2, frequently produced in CHO DG44 (Chinese Hamster Ovary) cells [1].</p>
Purezza:98%
Colore e forma:Liquid
Ref: TM-T80596
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Dacomitinib metabolite M2
CAS:
- 1262034-38-7
Dacomitinib metabolite M2 is also known as Dacomitinib cysteine conjugate. Dacomitinib inhibits both the wild-type (WT) EGFR and EGFR T790M.
Formula:C₂₇H₃₂ClFN₆O₄S
Colore e forma:Solid
Peso molecolare:591.1
Ref: TM-T23950