Angiogenesi

Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.

Sottocategorie di "Angiogenesi"

Mostrare 6 più sottocategorie

Trovati 2040 prodotti di "Angiogenesi"

Purezza (%)

100

prodotti per pagina.

+ Info
AG490
CAS:
- 133550-30-8
AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.
Formula:C₁₇H₁₄N₂O₃
Purezza:98.6% - 99.85%
Colore e forma:Yellow Solid
Peso molecolare:294.3
Ref: TM-T2600
+ Info
Crizotinib acetate
CAS:
- 877399-53-6
Crizotinib is an oral c-met/HGFR tyrosine kinase inhibitor with potential cancer-fighting properties.
Formula:C₂₃H₂₆Cl₂FN₅O₃
Colore e forma:Solid
Peso molecolare:510.39
Ref: TM-T1661L
+ Info
CA-4948
CAS:
- 1801344-14-8
CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.
Formula:C₂₄H₂₅N₇O₅
Purezza:99.35% - 99.88%
Colore e forma:Solid
Peso molecolare:491.5
Ref: TM-T9027
+ Info
Olverembatinib dimesylate
CAS:
- 1421783-64-3
Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).
Formula:C₂₉H₂₇F₃N₆O·2CH₄O₃S
Purezza:97.66% - >99.99%
Colore e forma:Solid
Peso molecolare:724.77
Ref: TM-T2429
+ Info
Tivozanib
CAS:
- 475108-18-0
Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.
Formula:C₂₂H₁₉ClN₄O₅
Purezza:98.08% - 99.67%
Colore e forma:Solid
Peso molecolare:454.86
Ref: TM-T2456
+ Info
SU6656
CAS:
- 330161-87-0
SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.
Formula:C₁₉H₂₁N₃O₃S
Purezza:98.21% - 98.73%
Colore e forma:Solid
Peso molecolare:371.45
Ref: TM-T6997
+ Info
XL228
CAS:
- 898280-07-4
XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).
Formula:C₂₂H₃₁N₉O
Purezza:99.07%
Colore e forma:Solid
Peso molecolare:437.54
Ref: TM-T17267
+ Info
Pacritinib hydrochloride
CAS:
- 1228923-43-0
Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.
Formula:C₂₈H₃₂N₄O₃·xClH
Colore e forma:Solid
Ref: TM-T64283
+ Info
CEP-37440
CAS:
- 1391712-60-9
CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).
Formula:C₃₀H₃₈ClN₇O₃
Purezza:98.86% - 99.98%
Colore e forma:Solid
Peso molecolare:580.12
Ref: TM-T2655
+ Info
PF-562271
CAS:
- 717907-75-0
PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
Formula:C₂₁H₂₀F₃N₇O₃S
Purezza:97.17% - >99.99%
Colore e forma:Solid
Peso molecolare:507.49
Ref: TM-T2465
+ Info
VEGFR-2-IN-5
CAS:
- 1430089-64-7
VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.
Formula:C₁₉H₂₄N₈
Purezza:99.92%
Colore e forma:Solid
Peso molecolare:364.45
Ref: TM-T2056
+ Info
Lapatinib tosylate
CAS:
- 1187538-35-7
Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).
Formula:C₃₆H₃₄ClFN₄O₇S₂
Colore e forma:Solid
Peso molecolare:753.26
Ref: TM-T72577
+ Info
EHop-016
CAS:
- 1380432-32-5
EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.
Formula:C₂₅H₃₀N₆O
Purezza:98.99% - >99.99%
Colore e forma:Solid
Peso molecolare:430.55
Ref: TM-T2427
+ Info
Oritinib mesylate
CAS:
- 2180164-79-6
Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.
Formula:C₃₂H₄₁N₇O₅S
Colore e forma:Solid
Peso molecolare:635.78
Ref: TM-T39670
+ Info
(S)-Afatinib
CAS:
- 439081-18-2
(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, L858R, L858R/T790M, HER2, and HER4, respectively.
Formula:C₂₄H₂₅ClFN₅O₃
Purezza:99.22% - >99.99%
Colore e forma:Off-White Solid
Peso molecolare:485.94
Ref: TM-T2303
+ Info
MELK-8a
CAS:
- 1922153-17-0
MELK-8a inhibits MELK kinase crucial for cancer cell mitosis (IC50: 2 nM).
Formula:C₂₅H₃₂N₆O
Colore e forma:Solid
Peso molecolare:432.56
Ref: TM-T62417
+ Info
ZM-447439
CAS:
- 331771-20-1
ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.
Formula:C₂₉H₃₁N₅O₄
Purezza:99.11% - 99.59%
Colore e forma:Pale Yellow Solid
Peso molecolare:513.59
Ref: TM-T6077
+ Info
2-(1,8-naphthyridin-2-yl)phenol
CAS:
- 65182-56-1
2-NP is a STAT1 enhancer.
Formula:C₁₄H₁₀N₂O
Purezza:99.33% - 99.82%
Colore e forma:Solid
Peso molecolare:222.24
Ref: TM-T2168
+ Info
AZ-5104
CAS:
- 1421373-98-9
AZ5104 is a potent EGFR inhibitor.
Formula:C₂₇H₃₁N₇O₂
Purezza:98.40% - 99.59%
Colore e forma:Solid Powder
Peso molecolare:485.58
Ref: TM-T2491
+ Info
Pamufetinib mesylate
CAS:
- 1688673-09-7
Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.
Formula:C₂₈H₂₇FN₄O₇S₂
Purezza:98.91%
Colore e forma:Solid
Peso molecolare:614.67
Ref: TM-T13108L