Angiogenesi
Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.
Sottocategorie di "Angiogenesi"
- BTK(162 prodotti)
- Bcr-Abl(117 prodotti)
- EGFR(594 prodotti)
- FAK(72 prodotti)
- FLT(90 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(183 prodotti)
- JAK(247 prodotti)
- PDGFR(127 prodotti)
- RAAS(90 prodotti)
- Src(81 prodotti)
- Syk(37 prodotti)
- Trombina(53 prodotti)
- VDA(2 prodotti)
- VEGFR(245 prodotti)
Mostrare 6 più sottocategorie
Trovati 2154 prodotti di "Angiogenesi"
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VEGFR-2-IN-23
CAS:VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.Formula:C22H15N5O2Colore e forma:SolidPeso molecolare:381.39Lck-IN-1
CAS:Lck-IN-1 is a potent inhibitor of lymphocyte protein tyrosine kinase (Lck) [1].Formula:C14H15N5Colore e forma:SolidPeso molecolare:253.3AGL 2043
CAS:AGL 2043 is a potent, reversible, ATP-competitive inhibitor of type III receptor tyrosine kinases.Formula:C15H12N4SColore e forma:SolidPeso molecolare:280.35α7 nAchR-JAK2-STAT3 agonist 1
CAS:α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM).Formula:C25H30O6Colore e forma:SolidPeso molecolare:426.5BCR-ABL-IN-5
CAS:BCR-ABL-IN-5: Bcr-Abl kinase inhibitor, IC50: Bcr-AblWT 0.014 μM, Bcr-AblT315I 0.45 μM; anti-leukemia cell growth.Formula:C25H21Cl2N5O2Colore e forma:SolidPeso molecolare:494.37Luxeptinib
CAS:Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.Formula:C25H17F4N5O2Colore e forma:SolidPeso molecolare:495.43GDC-4379
CAS:GDC-4379 is a JAK1 inhibitor that can be used to study asthma.Formula:C21H18ClF2N7O3Colore e forma:SolidPeso molecolare:489.86PHA-680626
CAS:PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).Formula:C23H26N6O2SColore e forma:SolidPeso molecolare:450.56EGFR-IN-63
CAS:EGFR- IN-63 is an EGFR inhibitor with an IC50 value of 0.096 μM. EGFR- IN-63 exhibited anticancer effects on MCF-7 cells (IC50: 2.49 μM).Formula:C20H12BrN5SColore e forma:SolidPeso molecolare:434.31BTK-IN-22
CAS:BTK-IN-22 is a selective BTK inhibitor with IC50 of 0.9 nM; also targets BLX, BMX (IC50s: 1.4, 1.2 nM); better selectivity than Ibrutinib.Formula:C26H26N6O2Colore e forma:SolidPeso molecolare:454.52pan-HER-IN-2
CAS:pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50Formula:C19H15BrClN5OColore e forma:SolidPeso molecolare:444.71EGFR/C797S-IN-1
CAS:EGFR/C797S-IN-1: Potent EGFR-C797S inhibitor, IC50 of 0.128 µM, dose-dependent p-EGFR suppression, anti-tumor properties.Formula:C28H30N4O3Colore e forma:SolidPeso molecolare:470.56PDGFRα/FLT3-ITD-IN-3
CAS:PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα (IC50: 0.153 μM), FLT3 (IC50: 0.004 μM) and PDGFRα/FLT3-ITD-IN-3 has the potential to beFormula:C26H39N9Colore e forma:SolidPeso molecolare:477.65CHMFL-ABL-053
CAS:CHMFL-ABL-053: potent, selective BCR-ABL/SRC/p38 inhibitor (IC50: 70/90/62 nM). Orally available, potential CML drug.Formula:C28H26F3N7O2Colore e forma:SolidPeso molecolare:549.55EGFR/HER2-IN-9
CAS:EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFRFormula:C25H25ClFN5O4Colore e forma:SolidPeso molecolare:513.95Ebselen oxide
CAS:Ebselen oxide (EB-2) is a HER2 inhibitor with antibacterial and antifungal activity and has shown cytoprotective effects against HN2 in vitro.Formula:C13H9NO2SePurezza:98%Colore e forma:SolidPeso molecolare:290.18SMU-B
CAS:SMU-B is a well-tolerated c-Met/ALK dual inhibitor.Formula:C26H25Cl2FN4O2Purezza:98%Colore e forma:SolidPeso molecolare:515.41BTK-IN-23
CAS:BTK-IN-23: BTK inhibitor, IC50=12.8 nM; also blocks BLX (35.6 nM), BMX (5.7 nM); better selectivity than Ibrutinib.Formula:C27H28N6O2Colore e forma:SolidPeso molecolare:468.55EGFR/CDK2-IN-1
CAS:EGFR/CDK2-IN-1, an inhibitor of both EGFR and CDK2, demonstrates effective cytotoxicity towards MCF7 and HepG2 cells, suggesting its potential application inFormula:C19H12BrClO2Colore e forma:SolidPeso molecolare:387.65Ficonalkib
CAS:Ficonalkib is a potent antineoplastic agent that inhibits the Anaplastic Lymphoma Kinase (ALK) tyrosine kinase receptor.Formula:C29H39N7O3SColore e forma:SolidPeso molecolare:565.73
