CymitQuimica logo
Angiogenesi

Angiogenesi

Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.

Sottocategorie di "Angiogenesi"

Mostrare 6 più sottocategorie

Trovati 2061 prodotti di "Angiogenesi"

Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • D-69491 hydrochloride
    Targetmol
    + Info

    D-69491 hydrochloride

    CAS:
    D-69491 hydrochloride is an inhibitor of HER-2 tyrosine kinase activity, blocking the phosphorylation of HER-2 and inhibiting the proliferation of SKOV-3 cells. It exhibits antitumor activity.
    Formula:C25H26Cl2FN7O3
    Colore e forma:Solid
    Peso molecolare:562.42

    Ref: TM-T201568

  • ALK ligand-Linker Conjugate 1
    Targetmol
    + Info

    ALK ligand-Linker Conjugate 1

    CAS:
    ALK ligand-Linker Conjugate 1 is an ALK ligand-connector conjugate used for the synthesis of PROTACALK degrader-4.
    Formula:C36H45N5O3
    Colore e forma:Solid
    Peso molecolare:595.77

    Ref: TM-T212133

  • Logo CymitQuimica
    Targetmol
    + Info

    Lazertinib mesylate

    CAS:
    <p>Lazertinib (mesylate) (YH25448 (mesylate); GNS-1480 (mesylate)) is an orally active EGFR inhibitor capable of crossing the blood-brain barrier. It suppresses the p-EGFR, p-AKT, and p-ERK signaling pathways, leading to apoptosis. Lazertinib (mesylate) demonstrates antitumor activity in the H1975-luc BM xenograft model in mice and is applicable for researching non-small cell lung cancer.</p>
    Formula:C31H38N8O6S
    Peso molecolare:650.75

    Ref: TM-T207270

  • NSC381467
    Targetmol
    + Info

    NSC381467

    CAS:
    NSC381467: Potent, oral EGFR-TK inhibitor with strong antiproliferative effects, promising for cancer research.
    Formula:C20H16O7
    Colore e forma:Solid
    Peso molecolare:368.34

    Ref: TM-T61441

  • VEGFR-2-IN-25
    Targetmol
    + Info

    VEGFR-2-IN-25

    CAS:
    VEGFR-2-IN-25 (compound 5d) is a potent inhibitor of VEGFR-2 (IC50: 12.1 nM).
    Formula:C24H22N6O2
    Colore e forma:Solid
    Peso molecolare:426.47

    Ref: TM-T62314

  • Tesevatinib tosylate
    Targetmol
    + Info

    Tesevatinib tosylate

    CAS:
    Tesevatinib tosylate (XL-647 tosylate) is an orally administered epidermal growth factor receptor (EGFR) inhibitor that can cross the blood-brain barrier. It significantly reduces cell viability with IC50 values of 11 nM and 102 nM in GBM12 and GBM6, respectively. Additionally, Tesevatinib tosylate inhibits HER2 (IC50=16.1 nM), VEGFR2 (IC50=1.5 nM), and Src (IC50=10.3 nM), demonstrating antitumor activity by inhibiting tumor proliferation.
    Formula:C31H33Cl2FN4O5S
    Colore e forma:Solid
    Peso molecolare:663.59

    Ref: TM-T201865

  • Logo CymitQuimica
    Targetmol
    + Info

    VEGFR-2/DHFR-IN-1

    Compound 8b inhibits VEGFR-2/DHFR, combats various bacteria, and fights cancer cells.
    Formula:C20H18ClNO4
    Colore e forma:Solid
    Peso molecolare:371.81

    Ref: TM-T61489

  • Logo CymitQuimica
    Targetmol
    + Info

    EGFR/HER2-IN-8

    EGFR/HER2-IN-8 inhibits EGFR, HER2, DHFR (IC50: 0.45, 0.244, 5.669 μM); useful in cancer research, safe and selective.
    Formula:C16H16N4O2S
    Colore e forma:Solid
    Peso molecolare:328.39

    Ref: TM-T60938

  • AZD0424
    Targetmol
    + Info

    AZD0424

    CAS:
    AZD0424: oral Src/Abl kinase inhibitor; potential anticancer; induces apoptosis, cell cycle arrest in lymphoma.
    Formula:C25H29ClN6O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:528.99

    Ref: TM-T14370

  • DDO-02267
    Targetmol
    + Info

    DDO-02267

    CAS:
    <p>DDO-02267 is a selective lysine-targeted covalent inhibitor of ALKBH5, with an IC50 value of 0.49 μM. It increases levels of N6-methyladenosine (m6A) and targets the ALKBH5-AXL signaling axis. DDO-02267 serves as a probe for studying the biological function of mRNA demethylases.</p>
    Formula:C18H12N2O7S
    Colore e forma:Solid
    Peso molecolare:400.362

    Ref: TM-T204967

  • Logo CymitQuimica
    Targetmol
    + Info

    FLT3/TrKA-IN-1

    FLT3/TrKA-IN-1: Potent dual kinase inhibitor for FLT3 & TrKA, promising for AML research.
    Formula:C28H30N4O2
    Colore e forma:Solid
    Peso molecolare:454.56

    Ref: TM-T62801

  • CEE321
    Targetmol
    + Info

    CEE321

    CAS:
    CEE321 is an effective pan-JAK inhibitor with an IC50 of 54 nM. It effectively inhibits biomarkers associated with atopic dermatitis.
    Formula:C18H16ClN5O
    Colore e forma:Solid
    Peso molecolare:353.806

    Ref: TM-T204824

  • Hypothemycin
    Targetmol
    + Info

    Hypothemycin

    CAS:
    Hypothemycin, a fungal polyketide, inhibits multiple kinases (VEGFR, MEK, FLT-3, PDGFR, ERK) with Kis ranging from 10 nM to 2.4 μM.
    Formula:C19H22O8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:378.37

    Ref: TM-T15542

  • PP487
    Targetmol
    + Info

    PP487

    CAS:
    PP487 is a dual tyrosine kinase/PI(3)K inhibitor, exhibiting IC50 values of 0.017 μM, 0.072 μM, 0.004 μM, 0.01 μM, 0.55 μM, 0.22 μM, and < 0.01 μM against DNA-PK, mTOR, Hck, Src, EGFR, EphB4, and PDGFR, respectively. It is applicable in cancer research [1].
    Formula:C14H14BrN5O
    Colore e forma:Solid
    Peso molecolare:348.2

    Ref: TM-T87238

  • Logo CymitQuimica
    Targetmol
    + Info

    Ten01

    Ten01 exhibits a 5.0 nM inhibition of JAK1 kinase.
    Formula:C18H20F6N4O
    Colore e forma:Solid
    Peso molecolare:422.37

    Ref: TM-T62257

  • Tyrphostin 63
    Targetmol
    + Info

    Tyrphostin 63

    CAS:
    Tyrphostin 63 (compound 13) is an epidermal growth factor receptor (EGFR) inhibitor, with an IC50 of 375 μM and a Ki of 123 μM.
    Formula:C10H8N2O
    Colore e forma:Solid
    Peso molecolare:172.183

    Ref: TM-T204167

  • UNC9750
    Targetmol
    + Info

    UNC9750

    CAS:
    UNC9750 is an inhibitor of inositol phosphate multikinase (IPMK), with IC50 values of 31.6 nM for IPMK and 374 nM for IP6K2. It effectively suppresses the accumulation of InsP5, a direct product of IPMK kinase activity, without affecting InsP6 or InsP7 levels. Additionally, UNC9750 inhibits over 75% of the activity of four kinases: DAPK1, DYRK1B, PDGFR, and KDR. This compound is applicable in glioblastoma research.
    Formula:C23H24N6O
    Colore e forma:Solid
    Peso molecolare:400.48

    Ref: TM-T212123

  • VVD-118313
    Targetmol
    + Info

    VVD-118313

    CAS:
    VVD-118313 (5a) is a potent JAK1 inhibitor targeting allosteric cysteine, blocking cytokine signaling for cancer research.
    Formula:C19H22Cl2N2O3S
    Colore e forma:Solid
    Peso molecolare:429.36

    Ref: TM-T62361

  • EGFR-IN-135
    Targetmol
    + Info

    EGFR-IN-135

    EGFR-IN-135 (compound 3d) is an EGFR inhibitor with an IC50 value of 0.086 µM. It inhibits cell growth and arrests the cell cycle in the S phase in breast cancer cell lines.
    Formula:C12H14N4OS2
    Colore e forma:Solid
    Peso molecolare:294.4

    Ref: TM-T201484

  • EGFR-IN-133
    Targetmol
    + Info

    EGFR-IN-133

    CAS:
    EGFR-IN-133 (Compound 24) serves as an inhibitor targeting various mutations of the EGFR, including the wild type, L858R/T790M, d19/T790M, L858R/T790M/C797S, and d19/T790M/C797S with respective IC50 values of 0.1, 0.044, 0.036, 0.04, and 0.054 nM. The compound exhibits favorable pharmacokinetic properties and high oral bioavailability.
    Formula:C27H29F2N7O3
    Colore e forma:Solid
    Peso molecolare:537.56

    Ref: TM-T201790