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Angiogenesi

Angiogenesi

Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.

Sottocategorie di "Angiogenesi"

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Trovati 2040 prodotti di "Angiogenesi"

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  • Logo CymitQuimica
    Targetmol
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    EGFR-IN-62

    EGFR-IN-62: IC50 of 10-242 nM for various EGFR mutations, blocks A549/H1975 cell cycle, induces apoptosis, and inhibits cell motility and proliferation.
    Formula:C30H33N9O2
    Colore e forma:Solid
    Peso molecolare:551.64

    Ref: TM-T63895

  • PF-06463922 acetate
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    PF-06463922 acetate

    CAS:
    PF-06463922 acetate: ALK/ROS1 inhibitor, brain- penetrable, active vs crizotinib-resistant mutants, in NSCLC trials.
    Formula:C23H23FN6O4
    Colore e forma:Solid
    Peso molecolare:466.46

    Ref: TM-T70060

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    FGFR1 inhibitor-6

    FGFR1 inhibitor-6, IC50: 16.31 nM, blocks cell cycle at pro-G1/G2/M and induces apoptosis.
    Formula:C27H19N5O4S2
    Colore e forma:Solid
    Peso molecolare:541.6

    Ref: TM-T63816

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    ALK-IN-23

    ALK-IN-23 inhibits ALK (IC50: 1.6-0.71 nM), hinders cancer cell spread, forms colonies in vitro, and reduces tumors in mice with low toxicity.
    Formula:C26H29ClN8O3S
    Colore e forma:Solid
    Peso molecolare:569.08

    Ref: TM-T64027

  • BTK-IN-10
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    BTK-IN-10

    CAS:
    BTK-IN-10 is a potent inhibitor of BTK, acting on wild-type BTK (IC50<5 nM) or mutant BTK (C481S) (IC50<5 nM).
    Formula:C25H24F2N4O2
    Colore e forma:Solid
    Peso molecolare:450.48

    Ref: TM-T62716

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    VEGFR-2-IN-14

    VEGFR-2-IN-14 (Compound 5) is a potent inhibitor of VEGFR-2, which inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.
    Formula:C24H23N3O3S
    Colore e forma:Solid
    Peso molecolare:433.52

    Ref: TM-T62439

  • (S)-3-Hydroxy Midostaurin
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    (S)-3-Hydroxy Midostaurin

    CAS:
    (S)-3-Hydroxy Midostaurin is a potent inhibitor of kinases(IC50 of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et)).
    Formula:C35H30N4O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:586.64

    Ref: TM-T12791

  • HER2-IN-7
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    HER2-IN-7

    CAS:
    HER2-IN-7 is a potent HER2 inhibitor with potential for researching ErbB-related diseases, especially cancer.
    Formula:C28H26F3N7O3
    Colore e forma:Solid
    Peso molecolare:565.55

    Ref: TM-T64003

  • NSC381467
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    NSC381467

    CAS:
    NSC381467: Potent, oral EGFR-TK inhibitor with strong antiproliferative effects, promising for cancer research.
    Formula:C20H16O7
    Colore e forma:Solid
    Peso molecolare:368.34

    Ref: TM-T61441

  • AZD0424
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    AZD0424

    CAS:
    AZD0424: oral Src/Abl kinase inhibitor; potential anticancer; induces apoptosis, cell cycle arrest in lymphoma.
    Formula:C25H29ClN6O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:528.99

    Ref: TM-T14370

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    Ten01

    Ten01 exhibits a 5.0 nM inhibition of JAK1 kinase.
    Formula:C18H20F6N4O
    Colore e forma:Solid
    Peso molecolare:422.37

    Ref: TM-T62257

  • VVD-118313
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    VVD-118313

    CAS:
    VVD-118313 (5a) is a potent JAK1 inhibitor targeting allosteric cysteine, blocking cytokine signaling for cancer research.
    Formula:C19H22Cl2N2O3S
    Colore e forma:Solid
    Peso molecolare:429.36

    Ref: TM-T62361

  • FGFR3-IN-4
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    FGFR3-IN-4

    CAS:
    FGFR3-IN-4 is a selective inhibitor targeting FGFR3, demonstrating an IC50 value of under 50 nM.
    Formula:C26H24ClN7O
    Colore e forma:Solid
    Peso molecolare:485.97

    Ref: TM-T73145

  • EGFR-IN-23
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    EGFR-IN-23

    CAS:
    EGFR-IN-23, identified as compound 8 in WO2021244502A1, is a potent EGFR tyrosine kinase inhibitor (TKI) demonstrating an inhibitory concentration (IC50) of 8.
    Formula:C36H44BrN10O3P
    Colore e forma:Solid
    Peso molecolare:775.68

    Ref: TM-T73104

  • Multi-kinase-IN-1
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    Multi-kinase-IN-1

    CAS:
    Multi-kinase-IN-1, a powerful kinase inhibitor, exhibits antitumor properties by inducing cell apoptosis.
    Formula:C35H36F2N6O6S
    Colore e forma:Solid
    Peso molecolare:706.76

    Ref: TM-T72604

  • JAK3/BTK-IN-3
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    JAK3/BTK-IN-3

    CAS:
    JAK3/BTK-IN-3: strong dual JAK3/BTK suppressor, promising for autoimmune disease research.
    Formula:C22H28N8O
    Colore e forma:Solid
    Peso molecolare:420.51

    Ref: TM-T62234

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    BTK inhibitor 18

    BTK inhibitor 18 is a selective, potent, covalent, orally active Btk inhibitor (IC50: 142 nM) that exhibits anti-inflammatory effects.
    Formula:C29H25N5O4S2
    Colore e forma:Solid
    Peso molecolare:571.67

    Ref: TM-T64042

  • JAK1-IN-9
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    JAK1-IN-9

    CAS:
    JAK1-IN-9 (compound 23a) is a potent, selective inhibitor of JAK1, demonstrating an IC50 of 72 nM.
    Formula:C16H13IN6
    Colore e forma:Solid
    Peso molecolare:416.22

    Ref: TM-T62155

  • FAK inhibitor 6
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    FAK inhibitor 6

    CAS:
    Compound 26F: potent enzyme inhibitor (IC50=28.2nM), low cytotoxicity (IC50=3.32μM), induces dose-dependent apoptosis in MDA-MB-231, blocks G0/G1 phase.
    Formula:C25H24FN5O2S
    Colore e forma:Solid
    Peso molecolare:477.55

    Ref: TM-T63123

  • JAK2-IN-11
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    JAK2-IN-11

    CAS:
    JAK2-IN-11 (Example 6) is a JAK2 kinase inhibitor with potent antitumor activity, exhibiting an IC50 of ≤10 nM against JH2 BIND WT/V617F. This compound effectively suppresses tumor growth.
    Formula:C31H31F3N8O4
    Colore e forma:Solid
    Peso molecolare:639.64

    Ref: TM-T201601