Angiogenesi
Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.
Sottocategorie di "Angiogenesi"
- BTK(159 prodotti)
- Bcr-Abl(115 prodotti)
- EGFR(594 prodotti)
- FAK(72 prodotti)
- FLT(90 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(182 prodotti)
- JAK(246 prodotti)
- PDGFR(126 prodotti)
- RAAS(90 prodotti)
- Src(81 prodotti)
- Syk(37 prodotti)
- Trombina(53 prodotti)
- VDA(2 prodotti)
- VEGFR(249 prodotti)
Mostrare 6 più sottocategorie
Trovati 2061 prodotti di "Angiogenesi"
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Trichilinin D
CAS:Trichilinin D is a natural product that can be used in related research in the field of life sciences. Its product number is TN8637.Formula:C37H44O8Peso molecolare:616.74Cediranib maleate
CAS:Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.Formula:C29H31FN4O7Colore e forma:SolidPeso molecolare:566.58Disitamab
CAS:Disitamab (RC48-0) is a humanized anti-HER2 monoclonal antibody used in ADC synthesis.Purezza:95.00%Colore e forma:LiquidN-piperidine Ibrutinib hydrochloride
CAS:N-piperidine Ibrutinib hydrochloride is a BTK inhibitor that inhibits WT BTK and C481S BTK , which inhibits the growth and proliferation of cancer cells.Formula:C22H23ClN6OPurezza:98.83%Colore e forma:SolidPeso molecolare:422.91Surfen dihydrochloride
CAS:Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a heparin sulfate antagonist with antimicrobial properties and inhibits blockade of signaling.Formula:C21H22Cl2N6OPurezza:97.08%Colore e forma:SolidPeso molecolare:445.35Gefitinib-d8
CAS:Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.Formula:C22H24ClFN4O3Purezza:98%Colore e forma:SolidPeso molecolare:454.95Ribociclib-d6
CAS:Ribociclib-d6 is a deuterated compound of Ribociclib (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.Formula:C23H30N8OColore e forma:SolidPeso molecolare:440.57Regorafenib-d3
CAS:<p>Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.</p>Formula:C21H15ClF4N4O3Purezza:98%Colore e forma:SolidPeso molecolare:485.83Pentagamavunon-1
CAS:PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.Formula:C23H24O3Colore e forma:SolidPeso molecolare:348.43KG-548
CAS:KG-548 is a dual inhibitor of ARNT/TACC3 and HIF-1α, inhibiting lactate production, and can be used in cancer research.Formula:C9H4F6N4Purezza:99.62%Colore e forma:SolidPeso molecolare:282.15A-770041
CAS:A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.Formula:C34H39N9O3Purezza:99.23% - 99.86%Colore e forma:SolidPeso molecolare:621.73Lck inhibitor 2
CAS:Lck inhibitor 2 blocks tyrosine kinases LCK, BTK, LYN, SYK, TXK with IC50s: Lck 13nM, Btk 9nM/26nM, Lyn 3nM, Txk 2nM.Formula:C18H17N5O2Colore e forma:SolidPeso molecolare:335.36GDC-0834
CAS:GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse andFormula:C33H36N6O3SColore e forma:SolidPeso molecolare:596.74AP23846
CAS:AP23846 is an Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines.Formula:C24H34N5OPPurezza:97.83%Colore e forma:SolidPeso molecolare:439.53AV-412 free base
CAS:AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).Formula:C27H28ClFN6OColore e forma:SolidPeso molecolare:507Elsubrutinib
CAS:Elsubrutinib (ABBV-105) is an orally active, selective, and irreversible BTK inhibitor with an IC50 of 0.18 μM for the catalytic domain of BTK.Formula:C17H19N3O2Purezza:99.77%Colore e forma:SolidPeso molecolare:297.36Aflibercept
CAS:Aflibercept has a wide range of applications in life science related research.Colore e forma:LiquidSM1-71
CAS:SM1-71 is a TAK1 inhibitor that inhibits MKNK2 and RSK2.SM1-71 acts as a kinase probe with anticancer activity.Formula:C24H26ClN7OPurezza:96%Colore e forma:SolidPeso molecolare:463.96SU14813 maleate
CAS:SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).Formula:C27H31FN4O8Purezza:98%Colore e forma:SolidPeso molecolare:558.56Rilematovir
CAS:Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.Formula:C21H20ClF3N4O3SPurezza:99.95%Colore e forma:SolidPeso molecolare:500.92Momelotinib sulfate
CAS:Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.Formula:C23H26N6O10S2Purezza:98%Colore e forma:SolidPeso molecolare:610.62Rociletinib hydrobromide
CAS:Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).Formula:C27H29BrF3N7O3Purezza:98%Colore e forma:SolidPeso molecolare:636.46N-Desethyl Sunitinib
CAS:N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,Formula:C20H23FN4O2Purezza:98%Colore e forma:SolidPeso molecolare:370.42Conteltinib tetrahydrochloride
Conteltinibtetrahydrochloride (CT-707 tetrahydrochloride) is the tetrahydrochloride form of Conteltinib. It acts as an inhibitor for FAK (IC50=1.6 nM), ALK, and Pyk2. When used in combination with Cabozantinib, Conteltinib tetrahydrochloride exhibits a synergistic antitumor effect.Formula:C32H49Cl4N9O3SColore e forma:SolidPeso molecolare:781.667Afatinib D6
CAS:Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.Formula:C24H25ClFN5O3Colore e forma:SolidPeso molecolare:491.98BPR1K871
CAS:BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values ofFormula:C25H28ClN7O2SColore e forma:SolidPeso molecolare:526.05SM27
CAS:SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.Formula:C21H16N2O9S2Purezza:98.83%Colore e forma:SolidPeso molecolare:504.49Tirbanibulin dihydrochloride
CAS:Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C26H31Cl2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:504.45EW-7195
CAS:<p>EW-7195 inhibits ALK5/TGFβR1 (>300x selective over p38α) with 4.83 nM IC50, blocking TGF-β1 signaling, EMT, and breast cancer lung metastasis.</p>Formula:C23H18N8Purezza:98.76%Colore e forma:SolidPeso molecolare:406.44iHCK-37
CAS:iHCK-37 (ASN05260065) is an Hck inhibitor with antitumor activity and blocks HIV-1 replication, used in chronic myelogenous leukemia (CML) research.Formula:C30H32N4O2S2Purezza:99.97%Colore e forma:SolidPeso molecolare:544.73(3S,4S)-PF-06459988
CAS:(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.Formula:C19H22ClN7O3Colore e forma:SolidPeso molecolare:431.88FLT3-IN-16
CAS:FLT3-IN-16 is a potent FLT3 inhibitor (IC50 = 1.1 μM) for acute myeloid leukemia research.Formula:C15H15N3O2SPurezza:99.21%Colore e forma:SolidPeso molecolare:301.36Imatinib D4
CAS:Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.Formula:C29H31N7OPurezza:98%Colore e forma:SolidPeso molecolare:497.63Telatinib mesylate
CAS:Telatinib mesylate is a potent, orally active inhibitor of VEGFR2 (IC50: 6 nM), VEGFR3 (IC50: 4 nM), PDGFα (IC50: 15 nM) and c-Kit (IC50: 1 nM).Formula:C21H20ClN5O6SColore e forma:SolidPeso molecolare:505.93Asciminib hydrochloride
CAS:Asciminib hydrochloride is a STAMP inhibitor targeting the ABL myristoyl pocket, applied in Ph+ CML research for selective oncogenic signaling modulation.Formula:C20H19Cl2F2N5O3Purezza:99.91%Colore e forma:SolidPeso molecolare:486.3(Z)-Orantinib
CAS:(Z)-Orantinib ((Z)-SU6668) is an orally active ATP-competitive inhibitor of Flk-1/KDR, PDGFRβ, and FGFR1, acting as a potent anti-angiogenic and anti-tumor agent.Formula:C18H18N2O3Purezza:98.05%Colore e forma:SolidPeso molecolare:310.35Itacitinib adipate
CAS:Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.Formula:C32H33F4N9O5Colore e forma:SolidPeso molecolare:699.66BI-3663
CAS:<p>BI-3663 is a selective PTK2/FAK PROTAC with cereblon ligands, degrading PTK2 (IC50: 18 nM), and shows anti-cancer properties.</p>Formula:C44H42F3N7O12Purezza:98%Colore e forma:SolidPeso molecolare:917.84Lestaurtinib
CAS:Lestaurtinib (CEP 701) is a FLT3 inhibitor that inhibits the phosphorylation of RPTKs and can be used to study leukemia.Formula:C26H21N3O4Purezza:99.17%Colore e forma:Off-White SolidPeso molecolare:439.46GMB-475
CAS:GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.Formula:C43H46F3N7O7SPurezza:98.78% - >99.99%Colore e forma:SolidPeso molecolare:861.93Gefitinib-based PROTAC 3
CAS:Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).Formula:C47H57ClFN7O8SPurezza:97.29% - 98.25%Colore e forma:SolidPeso molecolare:934.51AZ-5104
CAS:AZ5104 is a potent EGFR inhibitor.Formula:C27H31N7O2Purezza:98.40% - 99.59%Colore e forma:Solid PowderPeso molecolare:485.58AMP-945
CAS:AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.Formula:C28H32F3N5O2Purezza:99.76%Colore e forma:SolidPeso molecolare:527.58N-piperidine Ibrutinib
CAS:<p>N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively.</p>Formula:C22H22N6OPurezza:96.65%Colore e forma:SolidPeso molecolare:386.45Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formula:C25H27FN4O3Purezza:97.21% - 99.94%Colore e forma:SolidPeso molecolare:450.51CUDC-101
CAS:CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50s of 4.4, 2.4 and 15.7 nM, respectively.Formula:C24H26N4O4Purezza:95.76% - 99.17%Colore e forma:SolidPeso molecolare:434.49Pamufetinib mesylate
CAS:Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.Formula:C28H27FN4O7S2Purezza:98.91%Colore e forma:SolidPeso molecolare:614.67PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formula:C25H26F3N5O3Purezza:99.14% - 99.75%Colore e forma:SolidPeso molecolare:501.5Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Formula:C24H21BrFN5O2Purezza:99.07% - 99.62%Colore e forma:SolidPeso molecolare:510.36Dasatinib N-oxide
CAS:<p>Dasatinib N-oxide is a key metabolite and potential impurity of the kinase inhibitor dasatinib.</p>Formula:C22H26ClN7O3SPurezza:98.54% - 99.94%Colore e forma:SolidPeso molecolare:504
