Angiogenesi
Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.
Sottocategorie di "Angiogenesi"
- BTK(158 prodotti)
- Bcr-Abl(113 prodotti)
- EGFR(598 prodotti)
- FAK(72 prodotti)
- FLT(90 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(182 prodotti)
- JAK(246 prodotti)
- PDGFR(126 prodotti)
- RAAS(90 prodotti)
- Src(81 prodotti)
- Syk(37 prodotti)
- Trombina(53 prodotti)
- VDA(2 prodotti)
- VEGFR(250 prodotti)
Mostrare 6 più sottocategorie
Trovati 2040 prodotti di "Angiogenesi"
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(E/Z)-Zotiraciclib
CAS:(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formula:C23H24N4OPurezza:97.75% - 99.92%Colore e forma:SolidPeso molecolare:372.46Crizotinib acetate
CAS:Crizotinib is an oral c-met/HGFR tyrosine kinase inhibitor with potential cancer-fighting properties.Formula:C23H26Cl2FN5O3Colore e forma:SolidPeso molecolare:510.39Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurezza:97.56% - >99.99%Colore e forma:SolidPeso molecolare:498.64URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formula:C27H27N5Purezza:99.32% - 99.98%Colore e forma:SolidPeso molecolare:421.54(E)-AG 99
CAS:(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).Formula:C10H8N2O3Purezza:99.23%Colore e forma:SolidPeso molecolare:204.18ZM323881
CAS:ZM323881 is a potent and selective inhibitor of VEGFR2 with an IC 50 of less than 2 nM.Formula:C22H18FN3O2Colore e forma:SolidPeso molecolare:375.4Osimertinib
CAS:Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.Formula:C28H33N7O2Purezza:99.32% - >99.99%Colore e forma:SolidPeso molecolare:499.61PRT-060318
CAS:PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Formula:C18H24N6OPurezza:99.98%Colore e forma:SolidPeso molecolare:340.42Vandetanib hydrochloride
CAS:Vandetanib hydrochloride is an oral VEGFR2 inhibitor with an IC50 of 40 nM, also targeting VEGFR3 (110 nM) and EGFR (500 nM).Formula:C22H25BrClFN4O2Colore e forma:SolidPeso molecolare:511.81Tyrphostin B44, (+) enantiomer
CAS:Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)Formula:C18H16N2O3Purezza:97.18%Colore e forma:SolidPeso molecolare:308.33CA-4948
CAS:CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Formula:C24H25N7O5Purezza:99.35% - 99.88%Colore e forma:SolidPeso molecolare:491.5SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFormula:C17H15NO2Purezza:99.46%Colore e forma:SolidPeso molecolare:265.31Vatalanib free base
CAS:Vatalanib is a VEGFR2/KDR inhibitor (IC50: 37 nM).Formula:C20H15ClN4Purezza:99.52%Colore e forma:SolidPeso molecolare:346.81Tivozanib
CAS:Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.Formula:C22H19ClN4O5Purezza:98.08% - 99.67%Colore e forma:SolidPeso molecolare:454.86Nocodazole
CAS:Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formula:C14H11N3O3SPurezza:98% - 99.91%Colore e forma:Physical Description White Powder (Ntp 1992)Peso molecolare:301.32Mubritinib
CAS:Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.Formula:C25H23F3N4O2Purezza:98.61% - 99.85%Colore e forma:SolidPeso molecolare:468.47Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:266.29Tyrphostin A1
CAS:Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .Formula:C11H8N2OPurezza:98.32%Colore e forma:SolidPeso molecolare:184.19Saracatinib difumarate
CAS:Saracatinib difumarate is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities.Formula:C35H40ClN5O13Colore e forma:SolidPeso molecolare:774.18EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formula:C25H30N6OPurezza:98.99% - >99.99%Colore e forma:SolidPeso molecolare:430.55(S)-Afatinib
CAS:(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, L858R, L858R/T790M, HER2, and HER4, respectively.Formula:C24H25ClFN5O3Purezza:99.22% - >99.99%Colore e forma:Off-White SolidPeso molecolare:485.94JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Formula:C15H17ClN6O3Purezza:97.08%Colore e forma:SolidPeso molecolare:364.79CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Formula:C14H18N2O5Purezza:99.68%Colore e forma:White To Off-White SolidPeso molecolare:294.3SCR-1481B1
CAS:SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitorFormula:C32H40ClF2N6O13PPurezza:98.07%Colore e forma:SolidPeso molecolare:821.12Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormula:C31H33N5O4·C2H6O3SPurezza:99.43% - 99.98%Colore e forma:SolidPeso molecolare:649.76MELK-8a
CAS:MELK-8a inhibits MELK kinase crucial for cancer cell mitosis (IC50: 2 nM).Formula:C25H32N6OColore e forma:SolidPeso molecolare:432.56Almonertinib mesylate
CAS:Almonertinib mesylate: EGFR tyrosine kinase inhibitor, targets EGFR-mutant non-small cell lung cancer.Formula:C31H39N7O5SPurezza:99.92%Colore e forma:SolidPeso molecolare:621.75CHIR-124
CAS:CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.Formula:C23H22ClN5OPurezza:96.33% - 98.35%Colore e forma:SolidPeso molecolare:419.91Alectinib
CAS:Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.Formula:C30H34N4O2Purezza:98% - 99.38%Colore e forma:SolidPeso molecolare:482.62Crenolanib
CAS:Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).Formula:C26H29N5O2Purezza:98.40% - 99.73%Colore e forma:SolidPeso molecolare:443.54UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Formula:C19H25ClN8Purezza:99.52%Colore e forma:SolidPeso molecolare:400.91ODM-203
CAS:ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormula:C26H21F2N5O2SPurezza:99.85%Colore e forma:SolidPeso molecolare:505.54Crizotinib hydrochloride
CAS:Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formula:C21H23Cl3FN5OPurezza:98.73% - 98.87%Colore e forma:SolidPeso molecolare:486.8Zoligratinib
CAS:Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.Formula:C20H16N6OPurezza:95.28% - 99.51%Colore e forma:SolidPeso molecolare:356.38Vandetanib
CAS:Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formula:C22H24BrFN4O2Purezza:99.7% - >99.99%Colore e forma:White SolidPeso molecolare:475.35MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formula:C9H7NO4Purezza:98.53%Colore e forma:Yellow PowderPeso molecolare:193.16SU6656
CAS:SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.Formula:C19H21N3O3SPurezza:98.21% - 98.73%Colore e forma:SolidPeso molecolare:371.45Olverembatinib dimesylate
CAS:Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).Formula:C29H27F3N6O·2CH4O3SPurezza:97.66% - >99.99%Colore e forma:SolidPeso molecolare:724.774SC-203
CAS:<p>4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.</p>Formula:C33H38N8O4SPurezza:96.4% - 99.67%Colore e forma:SolidPeso molecolare:642.775-phenylthieno[2,3-d]pyrimidin-4-amine
CAS:5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.Formula:C12H9N3SPurezza:97%Colore e forma:SolidPeso molecolare:227.29Blu-782
CAS:<p>Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)</p>Formula:C31H42N6O4Purezza:99.51%Colore e forma:SolidPeso molecolare:562.7Ribociclib
CAS:Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50：10/39 nM).Formula:C23H30N8OPurezza:97.91% - >99.99%Colore e forma:SolidPeso molecolare:434.54AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formula:C17H14N2O3Purezza:98.6% - 99.85%Colore e forma:Yellow SolidPeso molecolare:294.3FIIN-3
CAS:FIIN-3 is an irreversible inhibitor of FGFR.Formula:C34H36Cl2N8O4Purezza:97.63% - 98.92%Colore e forma:SolidPeso molecolare:691.61Momelotinib HCl
CAS:<p>Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.</p>Formula:C23H24Cl2N6O2Colore e forma:SolidPeso molecolare:487.38Nazartinib
CAS:Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (Formula:C26H31ClN6O2Purezza:98.63% - ≥95%Colore e forma:Solid PowderPeso molecolare:495.02Pamufetinib mesylate
CAS:Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.Formula:C28H27FN4O7S2Purezza:98.91%Colore e forma:SolidPeso molecolare:614.67AZ-5104
CAS:AZ5104 is a potent EGFR inhibitor.Formula:C27H31N7O2Purezza:98.40% - 99.59%Colore e forma:Solid PowderPeso molecolare:485.58AC1NS4RE
CAS:It is a tyrosine kinase inhibitor.Formula:C15H13ClN2OPurezza:99.53%Colore e forma:SolidPeso molecolare:272.73PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formula:C26H35Cl2N7OPurezza:99.92%Colore e forma:SolidPeso molecolare:532.51
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