Angiogenesi
Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.
Sottocategorie di "Angiogenesi"
- BTK(162 prodotti)
- Bcr-Abl(117 prodotti)
- EGFR(593 prodotti)
- FAK(72 prodotti)
- FLT(90 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(183 prodotti)
- JAK(247 prodotti)
- PDGFR(127 prodotti)
- RAAS(90 prodotti)
- Src(81 prodotti)
- Syk(37 prodotti)
- Trombina(53 prodotti)
- VDA(2 prodotti)
- VEGFR(245 prodotti)
Mostrare 6 più sottocategorie
Trovati 2156 prodotti di "Angiogenesi"
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Rociletinib hydrobromide
CAS:Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).Formula:C27H29BrF3N7O3Purezza:98%Colore e forma:SolidPeso molecolare:636.46N-Desethyl Sunitinib
CAS:N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,Formula:C20H23FN4O2Purezza:98%Colore e forma:SolidPeso molecolare:370.42AV-412 free base
CAS:AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).Formula:C27H28ClFN6OColore e forma:SolidPeso molecolare:507Conteltinib tetrahydrochloride
Conteltinibtetrahydrochloride (CT-707 tetrahydrochloride) is the tetrahydrochloride form of Conteltinib. It acts as an inhibitor for FAK (IC50=1.6 nM), ALK, and Pyk2. When used in combination with Cabozantinib, Conteltinib tetrahydrochloride exhibits a synergistic antitumor effect.Formula:C32H49Cl4N9O3SColore e forma:SolidPeso molecolare:781.667Pentagamavunon-1
CAS:PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.Formula:C23H24O3Colore e forma:SolidPeso molecolare:348.43Afatinib D6
CAS:Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.Formula:C24H25ClFN5O3Colore e forma:SolidPeso molecolare:491.98SM27
CAS:SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.Formula:C21H16N2O9S2Purezza:98.83%Colore e forma:SolidPeso molecolare:504.49Tirbanibulin dihydrochloride
CAS:Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C26H31Cl2N3O3Purezza:98%Colore e forma:SolidPeso molecolare:504.45EW-7195
CAS:<p>EW-7195 inhibits ALK5/TGFβR1 (>300x selective over p38α) with 4.83 nM IC50, blocking TGF-β1 signaling, EMT, and breast cancer lung metastasis.</p>Formula:C23H18N8Purezza:98.76%Colore e forma:SolidPeso molecolare:406.44Imatinib D4
CAS:Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.Formula:C29H31N7OPurezza:98%Colore e forma:SolidPeso molecolare:497.63(3S,4S)-PF-06459988
CAS:(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.Formula:C19H22ClN7O3Colore e forma:SolidPeso molecolare:431.88iHCK-37
CAS:iHCK-37 (ASN05260065) is an Hck inhibitor with antitumor activity and blocks HIV-1 replication, used in chronic myelogenous leukemia (CML) research.Formula:C30H32N4O2S2Purezza:99.97%Colore e forma:SolidPeso molecolare:544.73FLT3-IN-16
CAS:FLT3-IN-16 is a potent FLT3 inhibitor (IC50 = 1.1 μM) for acute myeloid leukemia research.Formula:C15H15N3O2SPurezza:99.21%Colore e forma:SolidPeso molecolare:301.36Ref: TM-T9843
2mg37,00€5mg56,00€10mg90,00€25mg182,00€50mg274,00€100mg389,00€200mg513,00€1mL*10mM (DMSO)62,00€Asciminib hydrochloride
CAS:Asciminib hydrochloride is a STAMP inhibitor targeting the ABL myristoyl pocket, applied in Ph+ CML research for selective oncogenic signaling modulation.Formula:C20H19Cl2F2N5O3Purezza:99.91%Colore e forma:SolidPeso molecolare:486.3Ref: TM-T63226
1mg60,00€5mg137,00€10mg187,00€25mg305,00€50mg432,00€100mg655,00€1mL*10mM (DMSO)145,00€Telatinib mesylate
CAS:Telatinib mesylate is a potent, orally active inhibitor of VEGFR2 (IC50: 6 nM), VEGFR3 (IC50: 4 nM), PDGFα (IC50: 15 nM) and c-Kit (IC50: 1 nM).Formula:C21H20ClN5O6SColore e forma:SolidPeso molecolare:505.93Itacitinib adipate
CAS:Itacitinib adipate: oral JAK1 inhibitor, tested in phase II myelofibrosis trial.Formula:C32H33F4N9O5Colore e forma:SolidPeso molecolare:699.66BI-3663
CAS:BI-3663 is a selective PTK2/FAK PROTAC with cereblon ligands, degrading PTK2 (IC50: 18 nM), and shows anti-cancer properties.Formula:C44H42F3N7O12Purezza:98%Colore e forma:SolidPeso molecolare:917.84Lestaurtinib
CAS:Lestaurtinib (CEP 701) is a FLT3 inhibitor that inhibits the phosphorylation of RPTKs and can be used to study leukemia.Formula:C26H21N3O4Purezza:99.17%Colore e forma:Off-White SolidPeso molecolare:439.46SU14813 maleate
CAS:SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).Formula:C27H31FN4O8Purezza:98%Colore e forma:SolidPeso molecolare:558.56GMB-475
CAS:GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.Formula:C43H46F3N7O7SPurezza:98.78% - >99.99%Colore e forma:SolidPeso molecolare:861.93Ref: TM-T8488
1mg49,00€2mgPrezzo su richiesta5mg104,00€10mg169,00€25mg298,00€50mg439,00€100mg632,00€200mg882,00€1mL*10mM (DMSO)160,00€
