Angiogenesi
Gli inibitori dell'angiogenesi sono composti che interferiscono con la formazione di nuovi vasi sanguigni, un processo cruciale nella crescita e metastasi del cancro. Inibendo l'angiogenesi, questi composti possono limitare l'apporto di sangue ai tumori, rallentandone o arrestando la crescita. Gli inibitori dell'angiogenesi sono fondamentali nella ricerca sul cancro e nello sviluppo terapeutico, offrendo approfondimenti sui meccanismi di progressione tumorale e potenziali trattamenti per il cancro e altre malattie legate all'angiogenesi. Presso CymitQuimica, offriamo un'ampia gamma di inibitori dell'angiogenesi di alta qualità per supportare le tue ricerche in oncologia e biologia vascolare.
Sottocategorie di "Angiogenesi"
- BTK(162 prodotti)
- Bcr-Abl(117 prodotti)
- EGFR(591 prodotti)
- FAK(72 prodotti)
- FLT(90 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(183 prodotti)
- JAK(247 prodotti)
- PDGFR(127 prodotti)
- RAAS(90 prodotti)
- Src(81 prodotti)
- Syk(37 prodotti)
- Trombina(53 prodotti)
- VDA(2 prodotti)
- VEGFR(246 prodotti)
Mostrare 6 più sottocategorie
Trovati 2160 prodotti di "Angiogenesi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Benidipine hydrochloride
CAS:Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formula:C28H32ClN3O6Purezza:99.80%Colore e forma:SolidPeso molecolare:542.03Regorafenib monohydrate
CAS:Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormula:C21H17ClF4N4O4Purezza:99.69%Colore e forma:SolidPeso molecolare:500.83Ref: TM-T1792L
5mg35,00€10mg48,00€25mg69,00€50mg88,00€100mg140,00€200mg207,00€500mg348,00€1mL*10mM (DMSO)58,00€Vemurafenib
CAS:Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently.Formula:C23H18ClF2N3O3SPurezza:98% - 99.65%Colore e forma:SolidPeso molecolare:489.92SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFormula:C17H15NO2Purezza:99.46%Colore e forma:SolidPeso molecolare:265.31Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:266.29Ref: TM-T6711
2mg40,00€5mg58,00€10mg90,00€25mg180,00€50mg279,00€100mg411,00€200mg585,00€1mL*10mM (DMSO)81,00€AZD3759 hydrochloride
CAS:AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formula:C22H24Cl2FN5O3Purezza:99.62%Colore e forma:SolidPeso molecolare:496.36Ref: TM-T4249
2mg35,00€5mg48,00€10mg65,00€25mg99,00€50mg170,00€100mg280,00€200mg406,00€1mL*10mM (DMSO)51,00€Mubritinib
CAS:Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.Formula:C25H23F3N4O2Purezza:98.61% - 99.85%Colore e forma:SolidPeso molecolare:468.47CEP-28122 mesylate salt
CEP-28122 mesylate, a diaminopyrimidine, selectively inhibits ALK with IC50 of 1.9 nM and exhibits antitumor effects.Formula:C29H39ClN6O6SColore e forma:SolidPeso molecolare:635.17JK-P3
CAS:JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formula:C18H17N3O3Purezza:99.57%Colore e forma:SolidPeso molecolare:323.35Almonertinib mesylate
CAS:Almonertinib mesylate: EGFR tyrosine kinase inhibitor, targets EGFR-mutant non-small cell lung cancer.Formula:C31H39N7O5SPurezza:99.92%Colore e forma:SolidPeso molecolare:621.75Ref: TM-T9865
1mg55,00€5mg116,00€10mg187,00€25mg319,00€50mg449,00€100mg638,00€200mg840,00€1mL*10mM (DMSO)170,00€KX2-361
CAS:KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastomaFormula:C24H24FN3O2Purezza:99.64% - 99.68%Colore e forma:SolidPeso molecolare:405.46Ref: TM-T9411
1mg81,00€5mg170,00€10mg235,00€25mg386,00€50mg543,00€100mg730,00€200mg938,00€1mL*10mM (DMSO)182,00€PP1
CAS:PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.Formula:C16H19N5Purezza:99% - 99.88%Colore e forma:Off-White To Grey SolidPeso molecolare:281.36Ref: TM-T6196
1mg40,00€2mg52,00€5mg88,00€10mg118,00€25mg202,00€50mg283,00€100mg444,00€500mg998,00€1mL*10mM (DMSO)94,00€ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formula:C29H31N5O4Purezza:99.11% - 99.59%Colore e forma:Pale Yellow SolidPeso molecolare:513.59CHIR-124
CAS:CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.Formula:C23H22ClN5OPurezza:96.33% - 98.35%Colore e forma:SolidPeso molecolare:419.91Ref: TM-T6350
1mg42,00€2mg51,00€5mg81,00€10mg104,00€25mg170,00€50mg240,00€100mg359,00€1mL*10mM (DMSO)87,00€Blu-782
CAS:<p>Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)</p>Formula:C31H42N6O4Purezza:99.51%Colore e forma:SolidPeso molecolare:562.7MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formula:C9H7NO4Purezza:98.53%Colore e forma:Yellow PowderPeso molecolare:193.16Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFormula:C31H33N5O4·C2H6O3SPurezza:99.43% - 99.98%Colore e forma:SolidPeso molecolare:649.76Filgotinib
CAS:Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formula:C21H23N5O3SPurezza:98.03% - ≥95%Colore e forma:SolidPeso molecolare:425.5Ribociclib
CAS:Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50：10/39 nM).Formula:C23H30N8OPurezza:97.91% - >99.99%Colore e forma:SolidPeso molecolare:434.54Ref: TM-T6199
2mg43,00€5mg64,00€10mg86,00€25mg97,00€50mg116,00€100mg168,00€500mg420,00€1mL*10mM (DMSO)69,00€squarunkinA
CAS:squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-Formula:C25H32F3N5O4Purezza:99.29%Colore e forma:SolidPeso molecolare:523.55
